CN106442904B - A kind of drug dissolution tester - Google Patents
A kind of drug dissolution tester Download PDFInfo
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- CN106442904B CN106442904B CN201610847759.2A CN201610847759A CN106442904B CN 106442904 B CN106442904 B CN 106442904B CN 201610847759 A CN201610847759 A CN 201610847759A CN 106442904 B CN106442904 B CN 106442904B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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Abstract
The invention discloses a kind of drug dissolution testers, relate generally to drug inspection technical field.Including pedestal, four adjusting bolts are arranged in the edge of the pedestal, reference block is set on the pedestal, the reference block is equipped with air level, cylindrical boss is arranged in the top of the pedestal, heater box, annular water bath is arranged on the cylindrical boss, the annular lid of top setting of the annular water bath, elevating mechanism is set on the cylindrical boss, cylindrical housings are arranged in the top of the elevating mechanism, driving motor is arranged in the top of the cylindrical housings, annular array is equipped with several shafts in the cylindrical housings, stirring slurry is arranged in the bottom of the shaft, it is equipped with stripping rotor in the annular water bath.The beneficial effects of the present invention are：It can reduce the disturbing factor of Dissolution Rate Testing, can ensure the confidence level of testing result, can reduce dissolution tester and be corrected the required time, can improve working efficiency.
Description
Technical field
The present invention relates to drug inspection technical field, specifically a kind of drug dissolution tester.
Background technology
Dissolution rate refers to the speed and degree that drug is dissolved out from solid pharmaceutical preparations such as tablets in regulation solvent, and dissolution rate is piece
One important indicator of agent quality control.Currently, mostly using dissolution tester to test to the dissolution rate of drug, dissolve out
The testing result of degree tester is easily influenced by many factors, the axial line and the axle center line skew of stripping rotor, dissolution rate of shaft
Tester do not place horizontal, shaft verticality deviated big city cause stripping quantity increase (《Northwest pharmacy impurity》2010
Year December volume 25 the 6th is interim related record), it to solve such interference, needs before experiment, using level meter, square
Deng being corrected to dissolution tester, correction course occupies a large amount of time, and working efficiency is low, and existing dissolution rate tries
The water bath for testing instrument uses the electric-heating-wire-heating for being mounted on bottom, its surface will produce incrustation scale during heating wire long-time use
(application number：201420243202.4 patent name：A kind of modified Dissolution Rate Testing device), it easily causes different in water bath
The water temperature of position generates difference, and then influences the testing result of dissolution tester.
Invention content
The purpose of the present invention is to provide a kind of drug dissolution tester, it can reduce the interference of Dissolution Rate Testing because
Element can ensure the confidence level of testing result, can reduce dissolution tester and be corrected the required time, can improve work
Make efficiency.
The present invention to achieve the above object, is achieved through the following technical solutions：
Four adjusting bolts, the pedestal is arranged in the edge of a kind of drug dissolution tester, including pedestal, the pedestal
Upper setting reference block, the reference block are equipped with air level, and the top setting cylindrical boss of the pedestal, heater box are described
It is arranged with annular water bath on cylindrical boss, heating coil is wound in the heater box, is connected on the heating coil
Circulating pump is arranged in the heater box, passes through piping connection structure between the circulating pump, annular water bath, heater box for relay
At circulation loop, temperature sensor, the annular lid of top setting of the annular water bath, institute are equipped in the annular water bath
It states and elevating mechanism is set on cylindrical boss, cylindrical housings are arranged in the top of the elevating mechanism, the cylindrical housings
Driving motor is arranged in top, and the driving motor is located at the center of cylindrical housings, circular array in the cylindrical housings
Row are equipped with several shafts, and the axial line of the shaft is vertical with the top surface of reference block, and the top of the cylindrical housings is equipped with
The first support tube being adapted with shaft, the shaft are connect by first bearing with the first support tube, the cylindrical housings
Bottom be equipped with shaft be adapted the second support tube, the shaft is connect by second bearing with the second support tube, described
First bevel gear is set on driving motor, second bevel gear is set in the shaft, the first bevel gear, second bevel gear are equal
Positioned at the inside of cylindrical housings, the transmission shaft being adapted with shaft, the transmission shaft and circle are equipped in the circular cylindrical shell body
Cylindrical shell is rotatablely connected, and one end of the transmission shaft is equipped with the third hand tap gear engaged with first bevel gear, and the other end is equipped with
Stirring slurry is arranged in the 4th bevel gear engaged with second bevel gear, the bottom of the shaft, be equipped in the annular water bath with
The adaptable stripping rotor of stirring slurry, the annular lid are equipped with the through-hole being adapted with stripping rotor, the top of the stripping rotor
Equipped with the collar stop being adapted with through-hole, the bottom of the collar stop is arranged locating piece, the annular lid be equipped with
The adaptable location hole of locating piece, the shaft are equipped with the stripping cup cap being adapted with stripping rotor, the bottom of the stripping cup cap
The groove being adapted with collar stop is arranged in portion, and the axial line of the stripping cup cap is conllinear with the axial line of shaft, the dissolution
Cup lid is slidably connected with shaft, and touch screen is arranged in the cylindrical housings, and setting microcontroller controls in the circular cylindrical shell body
Device, the relay, temperature sensor, driving motor, touch screen are connect with singlechip controller signal.
The circulating pump is equipped with strainer.
Card slot is set on the cylindrical boss, the annular water bath is equipped with the first fixture block being adapted with card slot,
The annular lid is equipped with the second fixture block being adapted with card slot.
Guide post is arranged in the bottom of the cylindrical housings, and the cylindrical boss is equipped with leads with what guide post was adapted
To set.
Stop nut is set in the shaft, the stop nut is located at the top of stripping cup cap, the stop nut with
Spring is set between stripping cup cap, and one end of the spring is contacted with stop nut, and the other end is contacted with stripping cup cap, the bullet
Spring is set in shaft.
The prior art is compared, the beneficial effects of the present invention are：
1, temperature sensor of the invention is for detecting the temperature in annular water bath and testing result being sent to monolithic
Machine controller, singlechip controller are worked by controlling the actuation of relay to control heating coil, and heating coil is to heater box
Interior water heating constitutes circulation loop between circulating pump, annular water bath, heater box by piping connection, can be annular water
Bath cabinet provides constant water temperature, can avoid influence of the water temperature difference to testing result, horizontal base of the reference block as the present invention
Standard adjusts different adjusting bolts, can determine whether the top surface of reference block is horizontal by air level, the first support tube, second
Support tube can increase the support distances of shaft, can ensure that the verticality of shaft, bottom setting and the annular of stripping cup cap are kept off
The adaptable groove of block, the axial line of stripping cup cap is conllinear with the axial line of shaft, can ensure axial line and the dissolution of shaft
The axial line of cup is conllinear, can reduce the disturbing factor of Dissolution Rate Testing, can ensure the confidence level of testing result, can reduce
Dissolution tester is corrected the required time, can improve working efficiency.
2, driving motor of the invention can drive multiple shafts to rotate by Bevel Gear Transmission, can ensure annular water-bath
In case in multiple stripping rotors mixing speed consistency, the rotating speed different band of shaft in different stripping rotors can be avoided dry
It disturbs, locating piece is matched with location hole, and stripping rotor in checkout procedure can be avoided to deviate.
3, circulating pump of the invention is equipped with strainer, can be filtered, can keep away to entering the water in annular water bath
Exempt from incrustation scale and enters annular water bath.
4, card slot is set on cylindrical boss of the invention, the annular water bath is equipped with first be adapted with card slot
Fixture block, the annular lid are equipped with the second fixture block being adapted with card slot, and the first fixture block, the second fixture block are caught in card slot, energy
Annular water bath shakes with annular lid during enough avoiding experiment, can avoid shaking the interference to inspection result.
5, guide post is arranged in the bottom of cylindrical housings of the invention, and the cylindrical boss is equipped with and is mutually fitted with guide post
The guide sleeve answered can ensure that shaft vertically moves, and can improve the same of the axial line of shaft and the axial line of stripping rotor
Heart degree.
6, stop nut is set in shaft of the invention, the stop nut is located at the top of stripping cup cap, the limit
Spring is set between nut and stripping cup cap, one end of the spring is contacted with stop nut, and the other end is contacted with stripping cup cap,
The spring is set in shaft, and the pressing force of spring can be adjusted by stop nut, and elevating mechanism falls cylindrical housings
When lower, stripping cup cap is firmly pressed on stripping rotor by spring, can effectively avoid the evaporation of the liquid in stripping rotor.
Description of the drawings
Attached drawing 1 is the structural schematic diagram of the present invention；
Attached drawing 2 is the structural schematic diagram of annular water bath in embodiment；
Attached drawing 3 is the structural schematic diagram of annular lid in embodiment；
Attached drawing 4 is the internal drive structure chart of cylindrical housings in embodiment；
Attached drawing 5 is the structural schematic diagram of stripping rotor in embodiment.
Attached figure label：1, pedestal；2, adjusting bolt；3, reference block；4, cylindrical boss；5, heater box；6, annular water
Bath cabinet；7, circulating pump；8, temperature sensor；9, annular lid；10, elevating mechanism；11, cylindrical housings；12, driving motor；
13, shaft；14, the first support tube；15, the second support tube；16, first bevel gear；17, second bevel gear；18, transmission shaft；19、
Third hand tap gear；20, the 4th bevel gear；21, stirring slurry；22, stripping rotor；23, through-hole；24, collar stop；25, locating piece；
26, location hole；27, stripping cup cap；28, touch screen；29, the first fixture block；30, the second fixture block；31, guide post；32, guide sleeve；
33, stop nut；34, spring.
Specific implementation mode
Present invention will be further explained below with reference to specific examples.It should be understood that these embodiments are merely to illustrate the present invention
Rather than it limits the scope of the invention.In addition, it should also be understood that, after reading the content taught by the present invention, people in the art
Member can make various changes or modifications the present invention, and such equivalent forms equally fall within range defined herein.
Of the present invention is a kind of drug dissolution tester, including pedestal 1, and four tune are arranged in the edge of the pedestal 1
Bolt 2 is saved, reference block 3 is set on the pedestal 1, and the upper surface of reference block 3 is as horizontal reference of the invention, the reference block
3 are equipped with air level, adjust different adjusting bolts 2, can determine whether the top surface of reference block 3 is horizontal by air level.Institute
Top setting cylindrical boss 4, the heater box 5 of pedestal 1 are stated, annular water bath 6 is arranged on the cylindrical boss 4, it is described
It is wound with heating coil in heater box 5, relay is connected on the heating coil, circulating pump 7 is set in the heater box 5,
Circulation loop is constituted by piping connection between the circulating pump 7, annular water bath 6, heater box 5, in the annular water bath 6
Equipped with temperature sensor 8, temperature sensor 8 is for detecting the temperature in annular water bath 6 and testing result being sent to monolithic
Machine controller, singlechip controller are worked by controlling the actuation of relay to control heating coil, and heating coil is to heater box 5
Interior water heating constitutes circulation loop between circulating pump 7, annular water bath 6, heater box 5 by piping connection, can be annular
Water bath 6 provides constant water temperature, can avoid influence of the water temperature difference to testing result.The top of the annular water bath 6
Annular lid 9 is set, elevating mechanism 10 is set on the cylindrical boss 4, the top setting of the elevating mechanism 10 is cylindrical
Shell 11, elevating mechanism 10 is for driving cylindrical housings 11 to move up and down.The top setting driving of the cylindrical housings 11
Motor 12, the driving motor 12 are located at the center of cylindrical housings 11, and annular array is set in the cylindrical housings 11
There are several shafts 13, the axial line of the shaft 13 is vertical with the top surface of reference block 3, and the top of the cylindrical housings 11 is set
There is the first support tube 14 being adapted with shaft 13, the shaft 13 is connect by first bearing with the first support tube 14, described
The bottom of cylindrical housings 11 is equipped with the second support tube 15 being adapted with shaft 13, and the shaft 13 passes through second bearing and the
Two support tubes 15 connect, and the first support tube 14, the second support tube 15 can increase the support distances of shaft 13, can ensure shaft
13 verticality.First bevel gear 16 is set on the driving motor 12, second bevel gear 17 is set in the shaft 13, it is described
First bevel gear 16, second bevel gear 17 are respectively positioned on the inside of cylindrical housings 11, are equipped with and turn in the cylindrical housings 11
The adaptable transmission shaft 18 of axis 13, the transmission shaft 18 are rotatablely connected with cylindrical housings 11, and one end of the transmission shaft 18 is set
There are the third hand tap gear 19 engaged with first bevel gear 16, the other end to be equipped with the 4th bevel gear engaged with second bevel gear 17
20, driving motor 12 can drive multiple shafts 13 to rotate by Bevel Gear Transmission, can reduce energy consumption, can ensure annular water
In bath cabinet 6 in multiple stripping rotors 22 mixing speed consistency, the rotating speed of shaft 13 in different stripping rotors 22 can be avoided different
The interference brought.Stirring slurry 21 is arranged in the bottom of the shaft 13, is equipped in the annular water bath 6 and is adapted with stirring slurry 21
Stripping rotor 22, it is described annular lid 9 be equipped with stripping rotor 22 be adapted through-hole 23, the top of the stripping rotor 22 is equipped with
The collar stop 24 being adapted with through-hole 23, collar stop 24 can avoid stripping rotor 22 from sliding.The bottom of the collar stop 24
Locating piece 25 is arranged in portion, and the annular lid 9 is equipped with the location hole 26 being adapted with locating piece 25, locating piece 25 and location hole
26 match, and stripping rotor 22 in checkout procedure can be avoided to deviate.The shaft 13 is molten equipped with being adapted with stripping rotor 22
Go out cup lid 27, the groove that the bottom setting of the stripping cup cap 27 and collar stop 24 are adapted, the axis of the stripping cup cap 27
Heart line is conllinear with the axial line of shaft 13, and the stripping cup cap 27 is slidably connected with shaft 13, and stripping cup cap 27 is fallen, annular gear
Block 24 is caught in groove, can ensure that the axial line of shaft 13 is conllinear with the axial line of stripping rotor 22, can reduce dissolution rate examination
The disturbing factor tested can ensure the confidence level of testing result, can reduce dissolution tester and be corrected the required time,
Working efficiency can be improved.Touch screen 28 is set in the cylindrical housings 11, microcontroller is set in the cylindrical housings 11
Controller, the relay, temperature sensor 8, driving motor 12, touch screen 28 are connect with singlechip controller signal, are led to
Human-computer interaction can be carried out with the present invention by crossing touch screen 28.
In order to avoid incrustation scale enters annular water bath 6, the circulating pump 7 is equipped with strainer, can be to entering annular water-bath
Water in case 6 is filtered, and incrustation scale can be avoided to enter annular water bath 6.
In order to avoid shaking the interference to inspection result, card slot, the annular water bath are set on the cylindrical boss 4
6 are equipped with the first fixture block 29 being adapted with card slot, and the annular lid 9 is equipped with the second fixture block 30 being adapted with card slot,
First fixture block 29, the second fixture block 30 are caught in card slot, and annular water bath 6 shakes with annular lid 9 during capable of avoiding experiment,
It can avoid shaking the interference to inspection result.
In order to improve the concentricity of the axial line of shaft 13 and the axial line of stripping rotor 22, the bottom of the cylindrical housings 11
Guide post 31 is arranged in portion, and the cylindrical boss 4 is equipped with the guide sleeve 32 being adapted with guide post 31, can ensure shaft 13
It vertically moves, the concentricity of the axial line of shaft 13 and the axial line of stripping rotor 22 can be improved.
In order to effectively avoid the evaporation of the liquid in stripping rotor 22, stop nut 33, the limit are set in the shaft 13
Position nut 33 is located at the top of stripping cup cap 27, and spring 34, the bullet are arranged between the stop nut 33 and stripping cup cap 27
One end of spring 34 is contacted with stop nut 33, and the other end is contacted with stripping cup cap 27, and the spring 34 is set in shaft 13, is led to
The pressing force of spring 34 can be adjusted by crossing the position of stop nut 33, when elevating mechanism 10 falls cylindrical housings 11, spring
34 are firmly pressed on stripping cup cap 27 on stripping rotor 22, can effectively avoid the evaporation of the liquid in stripping rotor 22.
Embodiment：Of the present invention is a kind of drug dissolution tester, including pedestal 1, the edge setting of the pedestal 1
Four adjusting bolts 2, four adjusting bolts 2 are uniformly arranged at the edge of pedestal 1, and reference block 3, benchmark are arranged on the pedestal 1
Horizontal reference of the upper surface of block 3 as the present invention, the upper surface of the reference block 3 is inlaid with air level, adjusts different tune
Bolt 2 is saved, can determine whether the top surface of reference block 3 is horizontal by air level.Cylindrical boss is arranged in the top of the pedestal 1
4, heater box 5 are arranged with annular water bath 6 on the cylindrical boss 4, and the top of the cylindrical boss 4 is machined with and base
Card slot is arranged on the cylindrical boss 4 in the parallel top surface of quasi- block 3, and card slot is vertical with the top surface of cylindrical boss 4, the ring
Shape water bath 6 is equipped with the first fixture block 29 being adapted with card slot, and the first fixture block 29 is inserted into card slot, can avoid annular water-bath
Case 6 shakes, and can ensure that the bottom surface of annular water bath 6 is horizontal.Heating coil, the heating are wound in the heater box 5
It is connected with relay on coil, circulating pump 7 is set in the heater box 5, the water inlet end of the circulating pump 7 is inserted into heater box 5,
Water outlet be connected to the top of annular water bath 6, the bottom of annular water bath 6 far from the side of 7 water outlet of circulating pump equipped with
It is recycled back to by piping connection composition between the circulating pump 7, annular water bath 6, heater box 5 communicating pipe that heater box 5 is connected to
Road, the annular water bath 6 is interior to install four temperature sensors 8, and four temperature sensors 8 array in annular water bath is set
It sets, temperature sensor 8 is for detecting the temperature in annular water bath 6 and testing result being sent to singlechip controller, monolithic
Machine controller controls heating coil work by controlling the actuation of relay, and heating coil heats the water in heater box 5, follows
Circulation loop is constituted by piping connection between ring pump 7, annular water bath 6, heater box 5, can be that annular water bath 6 provides perseverance
Fixed water temperature can avoid influence of the water temperature difference to testing result.The water inlet end of the circulating pump 7 is equipped with strainer, can
It is filtered to entering the water in annular water bath 6, incrustation scale can be avoided to enter annular water bath 6.The annular water bath 6
The annular lid 9 of top setting, the annular lid 9 are equipped with the second fixture block 30 being adapted with card slot, and the second fixture block 30 is caught in
In card slot, annular lid 9 can be avoided to shake, and can ensure that the upper surface of annular lid 9 is horizontal.The cylindrical boss 4
Jack can be used in upper setting elevating mechanism 10, elevating mechanism 10, and the upper and lower surface of elevating mechanism 10 is parallel, the elevating mechanism
10 top is arranged cylindrical housings 11, and the center of the bottom of cylindrical housings 11 is machined with to be connect with elevating mechanism 10
Horizontal plane, elevating mechanism 10 is for driving cylindrical housings 11 to move up and down.The bottom of the cylindrical housings 11 is arranged four
Guide post 31, the cylindrical boss 4 are equipped with the guide sleeve 32 being adapted with guide post 31, can ensure that shaft 13 is vertical on
Lower movement can improve the concentricity of the axial line of shaft 13 and the axial line of stripping rotor 22.The top of the cylindrical housings 11
Driving motor 12 is installed in portion, and the driving motor 12 is located at the center of cylindrical housings 11, in the cylindrical housings 11
Annular array is set there are four shaft 13, and the axial line of the shaft 13 is vertical with the top surface of reference block 3, the cylindrical housings 11
Top be equipped with the first support tube 14 being adapted with shaft 13, the shaft 13 passes through first bearing and the first support tube 14 and connects
It connects, the bottom of the cylindrical housings 11 is equipped with the second support tube 15 being adapted with shaft 13, and the shaft 13 passes through second
Bearing is connect with the second support tube 15, and the first support tube 14, the second support tube 15 can increase the support distances of shaft 13, can
Ensure the verticality of shaft 13.First bevel gear 16 is set on the driving motor 12, the second cone tooth is set in the shaft 13
Wheel 17, the first bevel gear 16, second bevel gear 17 are respectively positioned on the inside of cylindrical housings 11, in the cylindrical housings 11
Equipped with the transmission shaft 18 being adapted with shaft 13, the transmission shaft 18 is rotatablely connected with cylindrical housings 11, the transmission shaft 18
One end be equipped with the third hand tap gear 19 that engage with first bevel gear 16, the other end is equipped with the 4th engaged with second bevel gear 17
Bevel gear 20, driving motor 12 can drive multiple shafts 13 to rotate, can reduce energy consumption, can ensure by Bevel Gear Transmission
In annular water bath 6 in multiple stripping rotors 22 mixing speed consistency, turning for shaft 13 in different stripping rotors 22 can be avoided
The interference that fast different band is come.Stirring slurry 21 is installed in the bottom of the shaft 13, is equipped with and stirring slurry 21 in the annular water bath 6
Adaptable stripping rotor 22, the annular lid 9 are equipped with the through-hole 23 being adapted with stripping rotor 22, the top of the stripping rotor 22
Portion is equipped with the collar stop 24 being adapted with through-hole 23, and collar stop 24 can avoid stripping rotor 22 from sliding.The collar stop
24 bottom is arranged locating piece 25, and the annular lid 9 is equipped with the location hole 26 being adapted with locating piece 25, locating piece 25 with
Location hole 26 matches, and stripping rotor 22 in checkout procedure can be avoided to deviate, can ensure the verticality of stripping rotor 22.Described turn
Axis 13 is equipped with the stripping cup cap 27 being adapted with stripping rotor 22, bottom setting and 24 phase of collar stop of the stripping cup cap 27
The axial line of the groove of adaptation, the stripping cup cap 27 is conllinear with the axial line of shaft 13, the stripping cup cap 27 and shaft 13
It is slidably connected, stripping cup cap 27 is fallen, and collar stop 24 is caught in groove, can ensure the axial line and stripping rotor 22 of shaft 13
Axial line it is conllinear, the disturbing factor of Dissolution Rate Testing can be reduced, can ensure the confidence level of testing result, can be reduced molten
Out-degree tester is corrected the required time, can improve working efficiency.The shaft 13 is multi-diameter shaft, in the shaft 13
Stop nut 33 is set, and the stop nut 33 is located at the top of stripping cup cap 27, the stop nut 33 and stripping cup cap 27
Between spring 34 is set, one end of the spring 34 contacts with stop nut 33, and the other end is contacted with stripping cup cap 27, the bullet
Spring 34 is set in shaft 13, and the pressing force of spring 34 can be adjusted by the position of stop nut 33, and elevating mechanism 10 will be justified
When cylindrical shell 11 is fallen, stripping cup cap 27 is firmly pressed on stripping rotor 22 by spring 34, can effectively avoid stripping rotor
The evaporation of liquid in 22.Touch screen 28 is set in the cylindrical housings 11, microcontroller is set in the cylindrical housings 11
Controller, the touch screen 28, temperature sensor 8 are connect with the input terminal of singlechip controller, the relay, driving motor
12 connect with the output end of singlechip controller, and human-computer interaction can be carried out with the present invention by touch screen 28.
Claims (5)
1. a kind of drug dissolution tester, including pedestal (1), it is characterized in that：Four adjustings are arranged in the edge of the pedestal (1)
Bolt (2), setting reference block (3) on the pedestal (1), the reference block (3) are equipped with air level, the top of the pedestal (1)
Cylindrical boss (4), heater box (5) is arranged in portion, and annular water bath (6), the heating are arranged on the cylindrical boss (4)
It is wound with heating coil on case (5), relay is connected on the heating coil, circulating pump is set on the heater box (5)
(7), circulation loop, the ring are constituted by piping connection between the circulating pump (7), annular water bath (6), heater box (5)
Temperature sensor (8), the annular lid (9) of top setting of the annular water bath (6), the circle are equipped in shape water bath (6)
Elevating mechanism (10), the top setting cylindrical housings (11) of the elevating mechanism (10), the circle are set in cylindrical end tangs (4)
The top setting driving motor (12) of cylindrical shell (11), the driving motor (12) are located at the centre bit of cylindrical housings (11)
It sets, annular array is equipped with several shafts (13), the axial line and benchmark of the shaft (13) on the cylindrical housings (11)
The top surface of block (3) is vertical, and the top of the cylindrical housings (11) is equipped with the first support tube (14) being adapted with shaft (13),
The shaft (13) is connect by first bearing with the first support tube (14), and the bottom of the cylindrical housings (11) is equipped with and turns
Adaptable the second support tube (15) of axis (13), the shaft (13) are connect by second bearing with the second support tube (15), institute
It states and first bevel gear (16) is set on driving motor (12), setting second bevel gear (17) on the shaft (13), described first
Bevel gear (16), second bevel gear (17) are respectively positioned on the inside of cylindrical housings (11), are equipped in the cylindrical housings (11)
The transmission shaft (18) being adapted with shaft (13), the transmission shaft (18) are rotatablely connected with cylindrical housings (11), the transmission
One end of axis (18) is equipped with the third hand tap gear (19) engaged with first bevel gear (16), and the other end is equipped with and second bevel gear
(17) the 4th bevel gear (20) engaged, the bottom setting stirring slurry (21) of the shaft (13), the annular water bath (6) are interior
Equipped with stirring slurry (21) be adapted stripping rotor (22), it is described annular lid (9) be equipped with stripping rotor (22) be adapted
Through-hole (23), the top of the stripping rotor (22) are equipped with the collar stop (24) being adapted with through-hole (23), the collar stop
(24) bottom setting locating piece (25), the annular lid (9) are equipped with the location hole (26) being adapted with locating piece (25),
The shaft (13) is equipped with the stripping cup cap (27) being adapted with stripping rotor (22), the bottom setting of the stripping cup cap (27)
The groove being adapted with collar stop (24), the axial line of the stripping cup cap (27) is conllinear with the axial line of shaft (13), institute
It states stripping cup cap (27) to be slidably connected with shaft (13), touch screen (28), the cylinder is set on the cylindrical housings (11)
Singlechip controller, the relay, temperature sensor (8), driving motor (12), touch screen (28) are set in shape shell (11)
It is connect with singlechip controller signal.
2. a kind of drug dissolution tester according to claim 1, it is characterized in that：The circulating pump (7) is equipped with filter
Net.
3. a kind of drug dissolution tester according to claim 1, it is characterized in that：It is set on the cylindrical boss (4)
Card slot is set, the annular water bath (6) is equipped with the first fixture block (29) being adapted with card slot, is set on the annular lid (9)
There is the second fixture block (30) being adapted with card slot.
4. a kind of drug dissolution tester according to claim 1, it is characterized in that：The bottom of the cylindrical housings (11)
Guide post (31) is arranged in portion, and the cylindrical boss (4) is equipped with the guide sleeve (32) being adapted with guide post (31).
5. a kind of drug dissolution tester according to claim 1, it is characterized in that：Limit is set on the shaft (13)
Nut (33), the stop nut (33) are located at the top of stripping cup cap (27), the stop nut (33) and stripping cup cap
(27) spring (34) is set between, and one end of the spring (34) is contacted with stop nut (33), the other end and stripping cup cap
(27) it contacts, the spring (34) is set in shaft (13).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610847759.2A CN106442904B (en) | 2016-09-23 | 2016-09-23 | A kind of drug dissolution tester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610847759.2A CN106442904B (en) | 2016-09-23 | 2016-09-23 | A kind of drug dissolution tester |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106442904A CN106442904A (en) | 2017-02-22 |
| CN106442904B true CN106442904B (en) | 2018-08-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610847759.2A Active CN106442904B (en) | 2016-09-23 | 2016-09-23 | A kind of drug dissolution tester |
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| CN (1) | CN106442904B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107020170B (en) * | 2017-05-13 | 2019-06-21 | 广州国标检验检测有限公司 | A kind of medical treatment detection monitor station of culture dish |
| CN109164015A (en) * | 2018-08-23 | 2019-01-08 | 沈阳奥吉娜药业有限公司 | PH meter drives calibration assemblies |
| CN110907616B (en) * | 2019-12-10 | 2022-04-12 | 上海信谊天平药业有限公司 | Medicine dissolution instrument for analyzing medicine dissolution rate |
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