CN106421507A - Medicine for treating toothache, and preparation method of medicine - Google Patents

Abstract

The invention discloses a medicine for treating toothache, and a preparation method of the medicine. The medicine is mainly prepared from the following components by a certain weight ratio: gypsum fibrosum, bittersweet herb, radix gentianae, folium mori, herba verbenae, herba ophioglossi, radix saposhnikoviae, cortex lycii radicis, herba asari, fructus piperis longi, bamboo leaves, radix rehmanniae, rhizoma cimicifugae, radix sophorae tonkinensis, liquorice root, achyranthes aspera, lotus stamen, black nightshade herb, spinyleaf pricklyash root, herb of lulek czarny, herba serissae, radix puerariae and pericarpium zanthoxyli. The medicine provided by the invention has the functions of clearing fire and detoxifying, dispelling wind and heat, relieving swelling and pain as well as dispelling wind and eliminating dampness; after being used for treating the toothache, the medicine has the advantages of quick effect, good treatment effect and no replase.

Description

A kind of treat medicine of toothache and preparation method thereof

Technical field

The present invention relates to a kind of treat medicine of toothache and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Toothache refers to the pain that tooth causes because of a variety of causes, is one of common symptom in oral disease, it is seen that in dental caries Tooth, pulpitiss, periapical periodontitiss, tooth trauma, dentin hypersensitiveness, wedge shaped defect etc..The traditional Chinese medical science then thinks and wind heat, stomach-fire, asthenic fire etc. Relevant, belong to gingival atrophy, osteomyelitis of the maxillary bone category.Due to western medicine large side effects, the Chinese medicines that therefore people are had a toothache to effectively treatment There is great demand in thing, up to now, it has not been found that the relevant report with regard to the present invention.

Content of the invention

The present inventor have found effectively treatment toothache finally according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial Medicine, so as to complete the present invention.

It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment toothache.

Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.

Medicine of the present invention be select Gypsum Fibrosum, Herba Solani Lyrati, Radix Gentianae, Rhizoma Paridis, Folium Mori, Herba Verbenae, Herba Ophioglossi, Radix Saposhnikoviae, Cortex Lycii, Herba Asari, Piper longum, Folium Bambusae, Radix Rehmanniae, Rhizoma Cimicifugae, Radix Sophorae Tonkinensiss, Radix Glycyrrhizae, Radix Achyranthis, Stamen Nelumbiniss, Herba Solani Nigri, Radix Zanthoxyli Spinifolii, Herba monochasmatis, Radix Serissae, Herba Plantaginiss, Thalictrum aquilegifolium L. var. sibiricum Regel, Fructus Viticises, the Radix Angelicae Dahuricae, Herba Menthae, Folium Nelumbinis, Radix Puerariae, Pericarpium Zanthoxyli, Herba Schizonepetae medicine are combined preparation, by these medicines Thing combination causes each efficacy of drugs to produce synergism such that it is able to which effectively treatment is had a toothache.Wherein from Gypsum Fibrosum, its property is because Acrid-sweet flavor, trembles with fear, enters lung, stomach, raw with there is expelling pathogenic factors from muscles for clearing heat, and the function that relieving restlessness is quenched the thirst is controlled calentura high fever and do not moved back, vexed coma, raves Language is gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach headache due to fire-evil, toothache, hyperactivity of toxic heat, spot dermexanthesis, and aphtha of the mouth and tongue is forged Deposited promoting tissue regeneration and ulcer healing, external treatment ulcer sores, burst and do not withdraw, the burning hot wound of soup.Its nature and flavor sweetness and bitterness is because from Herba Solani Lyrati, trembles with fear have clear Heat, dampness removing, wind-dispelling, the function of removing toxic substances, control malaria, jaundice, edema, gonorrhea, rheumatic arthritis, erysipelas, furuncle.From Radix Gentianae it is Because its nature and flavor hardship, trembles with fear, enter liver, gallbladder meridian have eliminating pathogen in the liver excess-fire, except the function of damp-heat in lower-JIAO, control Liver Channel intenseness of heat, and mania and irritation is hot-tempered, second Type encephalitis, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, carbuncle swells sore, scrotum swells and ache, pudendum pruritus due to damp pathogen.Its property is because from Rhizoma Paridis Bitter in the mouth, is slightly cold, slightly poisonous, return liver warp, has a heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the function of cool liver arresting convulsion, controls furuncle carbuncle, swelling throat Bitterly, venom, the pain of injury caused by falling and tumbling, convulsion with spasms.Its nature and flavor bitter sweet is because from Folium Mori, trembles with fear, enter lung, Liver Channel, have wind-dispelling clear Heat, the function of cooling blood for improving eyesight, dispelling the wind and dampness pathogens generate heat, headache, conjunctival congestion, thirsty, cough due to lung-heat, migratory arthralgia, urticaria, lower limb elephatiasis.Choosing Its nature and flavor hardship is because with Herba Verbenae, cool, enter liver, spleen channel, there is a heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, the function of inducing diuresis to remove edema, control diseases caused by exogenous pathogenic factor Heating, jaundice due to damp-heat, edema, dysentery, malaria, diphtheria, sore throat, gonorrhea, amenorrhea, abdominal mass, carbuncle sore tumefacting virus ulcerative gingivitis.From Herba Ophioglossi Its nature and flavor hardship is because, sweet, cool, enter Liver Channel, have a heat-clearing and toxic substances removing, the function of promoting blood circulation to remove blood stasis, control acute mastitis, furuncle, scabies itching over the body, falls Beat and damage, swelling and pain due to blood stasis.Its property acrid-sweet flavor is because from Radix Saposhnikoviae, temperature, enter bladder, lung, spleen channel, deliver, wind-dispelling, victory is wet, The function of pain relieving, controls affection of exogenous wind-cold, headache, dizzy, stiffness of the nape, anemofrigid-damp arthralgia, joint is ached, extremity contraction urgency, tetanus.Optionally Cortex Lycii is because that its nature and flavor is sweet, trembles with fear, enters lung, liver and kidney channel, has a heat clearing away, the function of removing heat from blood, controls asthenia hectic fever night sweat, lung heat cough and asthma, Spit blood, epistaxis, stranguria with blood, quench one's thirst, hypertension, carbuncle, malignant boil.It is because that its nature and flavor is pungent from Herba Asari, temperature, enter lung, kidney channel, dispel Wind, cold expelling, row water, function surreptitiously is opened, controls air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.It is because from Piper longum Its nature and flavor is pungent, heat, enters spleen, stomach, has a warming middle-JIAO, cold expelling, the therapeutic method to keep the adverse QI flowing downwards, and the function of pain relieving controls trusted subordinate's crymodynia, vomits acid regurgitation, and borborygmus are let out Rush down, cold-dysentery, scrotal hernia, headache, nasal sinusitis, toothache.Its property slightly sweet flavor is because from Folium Bambusae, trembles with fear that enter the heart, lung, gallbladder, stomach have clear Evanescence of heat is tired of, the function of diuresis of promoting the production of body fluid, and controls that calentura is tired to drink, and children shy, and cough with dyspnea tells nosebleed, flushed complexion, oliguria with reddish urine, erosion of the oral mucosa tongue boil.Choosing It is because that its nature and flavor is sweet with Radix Rehmanniae, trembles with fear that GUIXIN, liver and kidney channel have a clearing away heat and cooling blood, yin nourishing, the function of promoting the production of body fluid, pyreticosis polydipsia is controlled, Yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, Heat Diabetes, spit blood, epistaxis, spot dermexanthesis.The sweet pungent slight bitter of its nature and flavor is because from Rhizoma Cimicifugae, Cool, enter lung, spleen, stomach, have yang invigorating, deliver, rash, the function of removing toxic substances, seasonal epidemic pathogens epidemic disease labor is controlled, cold and heat of having a headache, laryngalgia, aphtha scar, Macule is impermeable, sinking of QI of middle-JIAO, protracted dysentery and diarrhea, proctoptosis, women's metrorrhagia and leukorrhagia, and uterus drops, carbuncle sore tumefacting virus.Which is because from Radix Sophorae Tonkinensiss Nature and flavor hardship, trembles with fear, and enter the heart, lung, three warp of large intestine relieve inflammation or internal heat, removing toxic substances, detumescence, and the function of pain relieving controls retropharyngeal abscess, acute throat trouble, sore throat, gingiva Swell and ache, dyspnea with fullness of the chest heat syndrome cough, jaundice, dysentery, haemorrhoids, heat is swollen, tinea alba, scabies, Serpentiss, worm, lyssodexis.Its nature and flavor is because from Radix Glycyrrhizae Gan Ping, enters spleen, stomach, lung meridian, has and middle emergency, lung moistening, removing toxic substances, and the function of coordinating the actions of various ingredients in a prescription is processed with controlling weakness of the spleen and stomach, lack of appetite, abdomen Pain loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, solution poison of drug And alimentary toxicosis.Its nature and flavor hardship is because from Radix Achyranthis, sour, put down, Return liver, kidney channel, have promoting blood circulation to remove blood stasis, damp eliminating diuresis, heat clearing away The function of removing toxic substances, controls gonorrhea, hematuria, women's amenorrhea, lump in the abdomen, rheumatic arthritis, tinea pedis, edema, dysentery, malaria, diphtheria, carbuncle Swollen, traumatic injury.Its property sweet-puckery flavor is because from Stamen Nelumbiniss, puts down, enter the heart, kidney channel, have and clear away heart-fire, kidney tonifying, arresting seminal emission, the work(of hemostasis Can, nocturnal emission lingering diarrhea is controlled, told, be defeated in battle, collapse, carry, dysentery.It is because that its nature and flavor is bitter, cold from Herba Solani Nigri, has heat clearing away, removing toxic substances, promoting blood circulation, disappear Swollen function, controls furuncle, carbuncle, erysipelas, osteopatia sprain, chronic tracheitiss, acute nephritiss.Its nature and flavor is because from Radix Zanthoxyli Spinifolii Pungent, temperature, Return liver, lung meridian, there is an expelling wind and cold, relaxing muscles and tendons to promote blood circulation, analgesic function, control cough due to wind and cold, rheumatic numbness, traumatic injury, Traumatic hemorrhage, constipation.Its nature and flavor hardship is because from Herba monochasmatis, puts down have a The flat liver of heat-clearing, the function of reducing swelling and alleviating pain, control anxious, Chronic hepatitiss, gastroenteritiss, stomatitis, laryngopharynx swelling and pain, toothache.Its nature and flavor hardship, pungent, cool, enter liver, spleen are because from Radix Serissae Warp, has wind-dispelling, dampness removing, heat clearing away, the function of removing toxic substances, dispelling the wind and dampness pathogens lumbago and skelalgia, dysentery, edema, conjunctival congestion and swelling pain, laryngalgia, toothache, women Leucorrhea, carbuncle, scrofula.It is because that its nature and flavor is sweet from Herba Plantaginiss, trembles with fear that enter liver, two warp of spleen have diuretic, heat clearing away, improving eyesight, eliminating the phlegm Function, control urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, jaundice, edema, hematodiarrhoea, have loose bowels, epistaxis, conjunctival congestion and swelling pain, sore throat tonsillitis, Cough, skin ulcer.Its nature and flavor hardship is because from Thalictrum aquilegifolium L. var. sibiricum Regel, trembles with fear that GUIXIN, liver, large intestine channel have clearing away heat-fire, dampness is detoxified Function, control Vexed, damp and hot rush down, lung-heat is coughed, conjunctival congestion and swelling pain, carbuncle furuncle.Its nature and flavor toil is because from Fructus Viticises, Cool, enter liver, stomach, bladder warp, there is dispelling wind and heat pathogens, the function of the clear profit head, anemopyretic cold is controlled, just, migraine, and toothache, acute conjunctivitis, mesh Pain, dim many tears, arthralgia chiefly caused by damp pathogen contracture in eyeball.It is because that its nature and flavor is pungent from the Radix Angelicae Dahuricae, temperature, enter lung, spleen, stomach, have a wind-dispelling, dampness, Detumescence, the function of pain relieving, control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-dampness stomachache, intestines wind anal fistula, leucorrhea with red and white discharge, carbuncle skin ulcer Infectionss, skin is dry itches, scabies.Be because that its nature and flavor is pungent from Herba Menthae, cool, enter lung, Liver Channel, have dispelling wind, radiating, ward off dirty, removing toxic substances Function, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, sore scabies, urticaria.From Folium Nelumbinis be because For its nature and flavor bitterness, put down, enter the heart, liver, spleen channel, have a clearing away summer-heat and eliminating dampness, sending up the lucid YANG, the function of hemostasis, diarrhea due to summer heat and dampness, dizziness is controlled, Aqueous vapor edema, thunder-headache, spit blood, epistaxis, metrorrhagia, have blood in stool, puerperal blood faintss.It is because that its nature and flavor is sweet pungent from Radix Puerariae, puts down, enter Spleen, stomach, have a yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, the function that relieving restlessness is only drunk, and control typhoid fever, control typhoid fever, warm headache stiffness of the nape, and dysphoria with smothery sensation disappears Yearningly, have loose bowels, dysentery, skin eruption is impermeable, hypertension, angina pectoriss, deaf.Be because that its nature and flavor is pungent from Pericarpium Zanthoxyli, temperature, poisonous, enter spleen, Lung, kidney channel, have warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, and parasite killing solves the function of fish raw meat poison, control food stagnation and stop drinking, trusted subordinate's crymodynia, vomiting, Oh, cough with dyspnea, anemofrigid-damp arthralgia, have loose bowels, dysentery, colic, toothache, ascariasis, enterobiasiss, pudendal pruritus, sore scabies.From Herba Schizonepetae be because Pungent for its nature and flavor, temperature, enter lung, Liver Channel, deliver, wind-dispelling, the function for the treatment of blood disorderss, fries charcoal hemostasis, cure cold heating, headache, throat Swell and ache, apoplexy locked mouth, spit blood, epistaxis, have blood in stool, metrorrhagia, puerperal blood faintss, carbuncle, sore scabies, scrofula.

Specific embodiment

The drug dose of instant component is also that inventor is drawn through groping in a large number to summarize, and the consumption of each component is following heavy All there is in the range of amount preferable curative effect：

12-18 gram of Gypsum Fibrosum, 10-15 gram of Herba Solani Lyrati, 8-12 gram of Radix Gentianae, 6-10 gram of Rhizoma Paridis, 8-12 gram of Folium Mori, 8-12 gram of Herba Verbenae, 8-12 gram of Herba Ophioglossi, 10-15 gram of Radix Saposhnikoviae, 8-12 gram of Cortex Lycii, 10-15 gram of Herba Asari, 12-18 gram of Piper longum, 8-12 gram of Folium Bambusae, the Radix Rehmanniae Yellow 10-15 gram, 8-12 gram of Rhizoma Cimicifugae, 15-25 gram of Radix Sophorae Tonkinensiss, 12-18 gram of Radix Glycyrrhizae, 8-12 gram of Radix Achyranthis, 8-12 gram of Stamen Nelumbiniss, Herba Solani Nigri 8- 12 grams, 8-12 gram of Radix Zanthoxyli Spinifolii, 12-18 gram of Herba monochasmatis, 15-25 gram of Radix Serissae, 8-12 gram of Herba Plantaginiss, 10-15 gram of Thalictrum aquilegifolium L. var. sibiricum Regel, wild pepper Sub- 15-25 gram, 12-18 gram of the Radix Angelicae Dahuricae, 15-25 gram of Herba Menthae, 8-12 gram of Folium Nelumbinis, 8-12 gram of Radix Puerariae, 6-10 gram of Pericarpium Zanthoxyli, Herba Schizonepetae 8-12 Gram.

Preferably：

15 grams of Gypsum Fibrosum, 12 grams of Herba Solani Lyrati, 10 grams of Radix Gentianae, 8 grams of Rhizoma Paridis, 10 grams of Folium Mori, 10 grams of Herba Verbenae, 10 grams of Herba Ophioglossi, Radix Saposhnikoviae 12 grams, 10 grams of Cortex Lycii, 12 grams of Herba Asari, 15 grams of Piper longum, 10 grams of Folium Bambusae, 12 grams of Radix Rehmanniae, 10 grams of Rhizoma Cimicifugae, 20 grams of Radix Sophorae Tonkinensiss, sweet 15 grams of grass, 10 grams of Radix Achyranthis, 10 grams of Stamen Nelumbiniss, 10 grams of Herba Solani Nigri, 10 grams of Radix Zanthoxyli Spinifolii, 15 grams of Herba monochasmatis, 20 grams of Radix Serissae, Herba Plantaginiss 10 Gram, 12 grams of Thalictrum aquilegifolium L. var. sibiricum Regel, 20 grams of Fructus Viticises, 15 grams of the Radix Angelicae Dahuricae, 20 grams of Herba Menthae, 10 grams of Folium Nelumbinis, 10 grams of Radix Puerariae, 8 grams of Pericarpium Zanthoxyli, Herba Schizonepetae 10 Gram.

The preparation method of medicine of the present invention is as follows

First, get the raw materials ready

1st, Gypsum Fibrosum：Remove miscellaneous stone, clean soil, it is broken into fritter；

2nd, Herba Solani Lyrati：Crude drug is taken, impurity is removed, clean, slightly moisten, cutting, dry；

3rd, Radix Gentianae：Impurity is picked, residual stem is removed, clean, rear cutting is run through, is dried；

4th, Rhizoma Paridis：Remove fibrous root, cleaning, drying；

5th, Folium Mori：Impurity is picked, stranding is broken, winnows with a dustpan destemming, weeds out spare；

6th, Herba Verbenae：Net impurity is picked, is cleaned, cutting is softened, is dried；

7th, Herba Ophioglossi：Spring, summer excavation whole herb with root, remove soil, clean, dry in the shade or using fresh herb；

8th, Radix Saposhnikoviae：Residual stem is removed, is soaked in water, pull out, section is run through, is dried；

9th, Cortex Lycii：Impurity and core is picked, is slightly washed, cutting, dry；

10th, Herba Asari：Cleared impurity, with water spray profit, timely cutting, dries；

11st, Piper longum：The removal of impurity is picked, handle is removed, well sifted ash is considered to be worth doing, and the used time smashs to pieces；

12nd, Folium Bambusae：Net impurity is picked, except destemming leaf, is dried；

13rd, Radix Rehmanniae：Crude drug is taken, impurity is removed, clean, slightly moisten, sheet is cut, dry, weed out chip；

14th, Rhizoma Cimicifugae：Impurity is picked, slightly foam washing is net, pulls out, runs through, section is dried；

15th, Radix Sophorae Tonkinensiss：Pick net impurity, thickness stepping, it is soaked in water, pulls out, cuts into slices after running through, dry；

16th, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant saturating when, pull out, run through, section, airing；

17th, Radix Achyranthis：Impurity is picked, is cleaned, cutting is run through, is dried；

18th, Stamen Nelumbiniss：Crude drug is taken, removes impurity；

19th, Herba Solani Nigri：Crude drug is taken, old stalk, impurity is removed, is cleaned, slightly moisten, cutting, dry；

20th, Radix Zanthoxyli Spinifolii：Spring, summer, Qiu Sanji can all be excavated, and dry, or take root bark and dry；

21st, Herba monochasmatis：Summer, autumn harvesting, dry；

22nd, Radix Serissae：Clean, cutting, using fresh herb or dry；

23rd, Herba Plantaginiss：Most soil is removed, is dried；

24th, Thalictrum aquilegifolium L. var. sibiricum Regel：Spring, autumn uproot stem and root, remove ground stem and leaf, wash away soil, dry；

25th, Fructus Viticises：Impurity is removed, is dried；

26th, the Radix Angelicae Dahuricae：Pick net impurity, wash, soak, pull out and run through, slightly shine to crust no soapy feeling when, then after moistening, cut Piece dries；

27th, Herba Menthae：Pick net impurity, remove undesirable root, first by leaf tremble lower separately put, then stem is sprayed clear water, runs through rear cutting, shine Dry, then with leaf and even；

28th, Folium Nelumbinis：Cleaned with water, cut off the base of a fruit and edge, shredding, dry；

29th, Radix Puerariae：Impurity is picked, is cleaned, be soaked in water, pull out, run through, cut into slices in time, dry；

30th, Pericarpium Zanthoxyli：Remove fruit stem and seed（Semen zanthoxyli）, put in pot fry to making sound, oil goes out, take out, cool；

31st, Herba Schizonepetae：Net impurity is picked, is slightly steeped with water, pull cutting out, dry.

2nd, prepare

1st, by the Gypsum Fibrosum of the weight, Herba Solani Lyrati, Radix Gentianae, Rhizoma Paridis, Folium Mori, Herba Verbenae, Herba Ophioglossi, Radix Saposhnikoviae, Cortex Lycii, Herba Asari, Piper longum, Folium Bambusae, Radix Rehmanniae, Rhizoma Cimicifugae, Radix Sophorae Tonkinensiss, Radix Glycyrrhizae, Radix Achyranthis, Stamen Nelumbiniss, Herba Solani Nigri, Radix Zanthoxyli Spinifolii, Herba monochasmatis, Radix Serissae, Herba Plantaginis Grass, Thalictrum aquilegifolium L. var. sibiricum Regel, Fructus Viticises, the Radix Angelicae Dahuricae, Herba Menthae, Folium Nelumbinis, Radix Puerariae, Pericarpium Zanthoxyli, Herba Schizonepetae are put in decocting container, and add water 8 times amount for the first time, After soaking 100 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time is decocted Liquid is poured in container；

2nd, the medicinal residues of filtration are added water 6 times amount, boils by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；

3rd, will decoction liquor mixing and stirring twice, be divided into 4 doses and take.

In prescription, Radix Sophorae Tonkinensiss relieve inflammation or internal heat, removing toxic substances, detumescence, and the function of pain relieving is monarch drug；Herba Menthae dispelling wind, radiating, ward off dirty, solution Poison；Fructus Viticises have dispelling wind and heat pathogens, the function of the clear profit head, and the two is that relieve inflammation or internal heat jointly by performance for ministerial drug, three taste medicines, removing toxic substances, and dispelling wind dissipates Heat, detumescence, the effect of pain relieving, treatment toothache effect is comprehensive, and to relieve inflammation or internal heat, can effect a permanent cure based on removing toxic substances, and Radix Serissae has wind-dispelling, profit Wet, heat clearing away, the function of removing toxic substances is adjuvant drug, and Radix Glycyrrhizae has and middle emergency, lung moistening, removing toxic substances, and the function of coordinating the actions of various ingredients in a prescription is to make medicine, with remainder All medicines are to take stopgap measures.

Medicine of the present invention has a Qinghuo Jiedu, dispelling wind and heat pathogens, reducing swelling and alleviating pain, the function of expelling wind and removing dampness, for treating toothache, Short treating period, instant effect, non-relapse after healing.

The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include this The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.

The animal toxicity test report of [test example 1] medicine of the present invention：

Take rabbit 30, male and female dual-purpose, 2.0 2.5kg of body weight, points two groups, per group 15, one of which is overdose test Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is that 10ml/kg, administering mode is given for administration by gavage Medicine, twice daily, serve on 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is no bad Toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1st, physical data

Accept toothache out-patient totally 30 for medical treatment.

2nd, diagnostic criteria

The feature of patient is shown as based on toothache, swelling and aching of gum, dysmasesises, thirsty halitosis, or when pain when stop, Spurs to the cold Severe Pain, buccal swelling etc.；Gingiva is scarlet or purplish red, swelling, soft, and gum edge has erosion or granulation tissue hyperplasia to turn up sometimes, Gingiva easy bleeding when brushing teeth or eating, but general no hematostaxises, patient's no obvious subjective symptomss, can have sometimes and itch Or sense of swelling.

3rd, Therapeutic Method

From above-mentioned medicament, take to patient, 1 dose is each taken, early daily, evening respectively takes 1 time, is within 5 days a course for the treatment of, continuously takes With 5 courses for the treatment of.

4th, efficacy assessment standard

Effective：Toothache symptom disappears, and body constitution recovers normal, recovery from illness；

Take a turn for the better：Patient's swelling and aching of gum phenomenon mitigates, and toothache symptom is clearly better, and body constitution is progressively recovered；

Invalid：Improvement standard person is not reached.

5th, therapeutic outcome（See the table below）

In above-mentioned treatment, with Drug therapy patient with toothache of the present invention 30, as a result effective 27, obvious effective rate is 90%, to take a turn for the better 2 Example, improvement rate is 6.67%, invalid 1, and total effective rate is 96.67%.

Claims (3)

1. a kind of medicine for treating toothache, it is characterised in that：It is made up of the crude drug in following weight range：

12-18 gram of Gypsum Fibrosum, 10-15 gram of Herba Solani Lyrati, 8-12 gram of Radix Gentianae, 6-10 gram of Rhizoma Paridis, 8-12 gram of Folium Mori, 8-12 gram of Herba Verbenae, 8-12 gram of Herba Ophioglossi, 10-15 gram of Radix Saposhnikoviae, 8-12 gram of Cortex Lycii, 10-15 gram of Herba Asari, 12-18 gram of Piper longum, 8-12 gram of Folium Bambusae, the Radix Rehmanniae Yellow 10-15 gram, 8-12 gram of Rhizoma Cimicifugae, 15-25 gram of Radix Sophorae Tonkinensiss, 12-18 gram of Radix Glycyrrhizae, 8-12 gram of Radix Achyranthis, 8-12 gram of Stamen Nelumbiniss, Herba Solani Nigri 8- 12 grams, 8-12 gram of Radix Zanthoxyli Spinifolii, 12-18 gram of Herba monochasmatis, 15-25 gram of Radix Serissae, 8-12 gram of Herba Plantaginiss, 10-15 gram of Thalictrum aquilegifolium L. var. sibiricum Regel, wild pepper Sub- 15-25 gram, 12-18 gram of the Radix Angelicae Dahuricae, 15-25 gram of Herba Menthae, 8-12 gram of Folium Nelumbinis, 8-12 gram of Radix Puerariae, 6-10 gram of Pericarpium Zanthoxyli, Herba Schizonepetae 8-12 Gram.

2. medicine according to claim 1, the consumption of wherein each crude drug is：

15 grams of Gypsum Fibrosum, 12 grams of Herba Solani Lyrati, 10 grams of Radix Gentianae, 8 grams of Rhizoma Paridis, 10 grams of Folium Mori, 10 grams of Herba Verbenae, 10 grams of Herba Ophioglossi, Radix Saposhnikoviae 12 grams, 10 grams of Cortex Lycii, 12 grams of Herba Asari, 15 grams of Piper longum, 10 grams of Folium Bambusae, 12 grams of Radix Rehmanniae, 10 grams of Rhizoma Cimicifugae, 20 grams of Radix Sophorae Tonkinensiss, sweet 15 grams of grass, 10 grams of Radix Achyranthis, 10 grams of Stamen Nelumbiniss, 10 grams of Herba Solani Nigri, 10 grams of Radix Zanthoxyli Spinifolii, 15 grams of Herba monochasmatis, 20 grams of Radix Serissae, Herba Plantaginiss 10 Gram, 12 grams of Thalictrum aquilegifolium L. var. sibiricum Regel, 20 grams of Fructus Viticises, 15 grams of the Radix Angelicae Dahuricae, 20 grams of Herba Menthae, 10 grams of Folium Nelumbinis, 10 grams of Radix Puerariae, 8 grams of Pericarpium Zanthoxyli, Herba Schizonepetae 10 Gram.

3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：

（One）Get the raw materials ready

（1）Gypsum Fibrosum：Remove miscellaneous stone, clean soil, it is broken into fritter；

（2）Herba Solani Lyrati：Crude drug is taken, impurity is removed, clean, slightly moisten, cutting, dry；

（3）Radix Gentianae：Impurity is picked, residual stem is removed, clean, rear cutting is run through, is dried；

（4）Rhizoma Paridis：Remove fibrous root, cleaning, drying；

（5）Folium Mori：Impurity is picked, stranding is broken, winnows with a dustpan destemming, weeds out spare；

（6）Herba Verbenae：Net impurity is picked, is cleaned, cutting is softened, is dried；

（7）Herba Ophioglossi：Spring, summer excavation whole herb with root, remove soil, clean, dry in the shade or using fresh herb；

（8）Radix Saposhnikoviae：Residual stem is removed, is soaked in water, pull out, section is run through, is dried；

（9）Cortex Lycii：Impurity and core is picked, is slightly washed, cutting, dry；

（10）Herba Asari：Cleared impurity, with water spray profit, timely cutting, dries；

（11）Piper longum：The removal of impurity is picked, handle is removed, well sifted ash is considered to be worth doing, and the used time smashs to pieces；

（12）Folium Bambusae：Net impurity is picked, except destemming leaf, is dried；

（13）Radix Rehmanniae：Crude drug is taken, impurity is removed, clean, slightly moisten, sheet is cut, dry, weed out chip；

（14）Rhizoma Cimicifugae：Impurity is picked, slightly foam washing is net, pulls out, runs through, section is dried；

（15）Radix Sophorae Tonkinensiss：Pick net impurity, thickness stepping, it is soaked in water, pulls out, cuts into slices after running through, dry；

（16）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant saturating when, pull out, run through, section, airing；

（17）Radix Achyranthis：Impurity is picked, is cleaned, cutting is run through, is dried；

（18）Stamen Nelumbiniss：Crude drug is taken, removes impurity；

（19）Herba Solani Nigri：Crude drug is taken, old stalk, impurity is removed, is cleaned, slightly moisten, cutting, dry；

（20）Radix Zanthoxyli Spinifolii：Spring, summer, Qiu Sanji can all be excavated, and dry, or take root bark and dry；

（21）Herba monochasmatis：Summer, autumn harvesting, dry；

（22）Radix Serissae：Clean, cutting, using fresh herb or dry；

（23）Herba Plantaginiss：Most soil is removed, is dried；

（24）Thalictrum aquilegifolium L. var. sibiricum Regel：Spring, autumn uproot stem and root, remove ground stem and leaf, wash away soil, dry；

（25）Fructus Viticises：Impurity is removed, is dried；

（26）The Radix Angelicae Dahuricae：Pick net impurity, wash, soak, pull out and run through, slightly shine to crust no soapy feeling when, then after moistening, cut Piece dries；

（27）Herba Menthae：Pick net impurity, remove undesirable root, first by leaf tremble lower separately put, then stem is sprayed clear water, runs through rear cutting, shine Dry, then with leaf and even；

（28）Folium Nelumbinis：Cleaned with water, cut off the base of a fruit and edge, shredding, dry；

（29）Radix Puerariae：Impurity is picked, is cleaned, be soaked in water, pull out, run through, cut into slices in time, dry；

（30）Pericarpium Zanthoxyli：Remove fruit stem and seed, Semen zanthoxyli, put in pot fry to making sound, oil goes out, take out, cool；

（31）Herba Schizonepetae：Net impurity is picked, is slightly steeped with water, pull cutting out, dry；

（Two）Prepare

（1）By the Gypsum Fibrosum of the weight, Herba Solani Lyrati, Radix Gentianae, Rhizoma Paridis, Folium Mori, Herba Verbenae, Herba Ophioglossi, Radix Saposhnikoviae, Cortex Lycii, Herba Asari, Piper longum, Folium Bambusae, Radix Rehmanniae, Rhizoma Cimicifugae, Radix Sophorae Tonkinensiss, Radix Glycyrrhizae, Radix Achyranthis, Stamen Nelumbiniss, Herba Solani Nigri, Radix Zanthoxyli Spinifolii, Herba monochasmatis, Radix Serissae, Herba Plantaginis Grass, Thalictrum aquilegifolium L. var. sibiricum Regel, Fructus Viticises, the Radix Angelicae Dahuricae, Herba Menthae, Folium Nelumbinis, Radix Puerariae, Pericarpium Zanthoxyli, Herba Schizonepetae are put in decocting container, and add water 8 times amount, are soaked After 100 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is fallen Enter in container；

（2）The medicinal residues of filtration are added water 6 times amount, is boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；

（3）Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 4 doses and takes.