CN106421409A - Traditional Chinese medicine preparation for treating stomach illness and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating stomach illness and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine preparation for treating stomach illness, which is prepared from the following raw materials in parts by weight: 35 to 45 parts of fructus evodiae, 5 to 10 parts of hedgehog fungus powder, 2 to 5 parts of rhizoma corydalis, 6 to 12 parts of ossa sepiae, 10 to 20 parts of danshen root, 15 to 25 parts of hemsleya amabilis, 3 to 6 parts of radix inulae, 20 to 30 parts of wasabia japonica, 10 to 16 parts of bletilla striata, 3 to 10 parts of radix ophiopogonis, 2 to 5 parts of radix scutellariae, 4 to 8 parts of lobedfruit schizocapsa rhizome, 10 to 20 parts of rhizoma cimicifugae, 2 to 5 parts of taraxacum, and 4 to 12 parts of rodgersflower rhizome. The medicines adopted by the invention are organically combined and synergized according to a monarch, minister, assistant and guide principle, so that the traditional Chinese medicine preparation has a better curative effect on various symptoms of digestive tract, treats both symptoms and root causes, and has major functions on treating acute gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, gastrorrhagia and non-ulcer dyspepsia. The traditional Chinese medicine preparation provided by the invention is prepared from pure traditional medicines, is convenient to use, safe and reliable, has no toxic or side effects on liver, kidney, lungs, stomach or spleen, and can be taken for a long time.
Description
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of treat Chinese medicine preparation of gastropathy and preparation method thereof.
Background technology
The general designation of gastropathy, actually various disease conditions；They have similar symptom, such as epigastric discomfort or pain, nausea,
Vomiting, diarrhoea, inappetence, the symptom of gastric and duodenal ulcers is then epigastrium burning pain, and severe patient can have tarry stool, black
Just or hemafecia etc..Clinically common gastropathy has acute gastritiss, chronic gastritiss, gastric ulcer, duodenal ulcer, stomach 12 finger
Intestinal complex ulcer, polyp of stomach, gastric calculus, the innocent and malignant tumour of stomach, also prolapse of gastric mucosa, acute gastric dilatation, pyloric obstruction
Deng.It is reported that：In Chinese society population, 10% people is had to suffer from gastric ulcer, nearly 25% patient has various gastritis, at present
National patients with gastric disease total number of persons rough estimate has nearly 300,000,000 people, the height of the sickness rate of China's gastropathy, as many as number of the infected Yi Ju world
First of, existing multiple Western medicine or Chinese medicine or other treatment method are used for the treatment of gastropathy both at home and abroad, but therapeutic process is mostly more
Very long, produced by drug accumulation, toxic and side effects are appeared in the newspapers repeatly, and patient bears higher security risk and inconvenience.
In prior art, the Chinese patent medicine for treating gastropathy is more, but mostly just for topical condition, digests for whole
The physical recovery that the recovery of systemic-function and system organic disease become then acts on poor, and is easy to after symptom eliminates recur.《Chinese medicine
Prescribed preparation》Under 8th WS3-B-1590-93 item, " FUFANG WEINING PIAN " is exactly the medicine treating gastric abscess, and its prescription consists of：
Rhizoma Corydalis, hedgehog hydnum mycopowder, Endoconcha Sepiae, clinically application achieves certain effect, but it clinically there is also significantly
Shortcoming, the physical recovery that the recovery for whole digestive system function and system organic disease become then acts on poor, and symptom
It is easy to after elimination recur；And it is coated tablet, complex process, the easy moisture absorption goes bad, and diabetic can not be taken.But the traditional Chinese medical science
Treatment chronic gastritiss curative effect is rather good, and effective percentage is up to 40%-73%.Chinese medicine thinks that chronic gastritiss belong to " stomach painful abdominal mass disease " category,《Interior
Warp》Stomach painful abdominal mass disease is referred to as " painful abdominal mass " " feeling of fullness " " painful abdominal mass plug " etc..As《The big opinion of Plain Questions 5 constant virtues political affairs》Say：" its disease that standby turns to discipline ...
Painful abdominal mass ", " its disease of the discipline ... of inferior prison stays full painful abdominal mass plug ".Written by Zhang Zhongjing it《Treatise on Febrile Diseases》Then stomach painful abdominal mass disease is called " epigastric oppression ", and right
This sick principle-method-recipe-medicines is discussed in detail, and says：" but feeling fullness but no pain person, be cited as painful abdominal mass ", " diseases occurring in YIN meridians or ZANG FU-organs and anti-purgation, because making
Painful abdominal mass ".The position that next explicitly points out painful abdominal mass location is gastral cavilty portion under the heart, and its primary symptom has the sense of stifled vexed painful abdominal mass plug for gastral cavilty portion, by it
Soft.Stomach be reservoir of food and drink, master received, lead to drop diet water paddy, be energy and blood of human body the source of vital function spring, the vital organs of the human body be all bullied in
Stomach, so stomach is for the vital organs of the human body originally.Gastropathy then affects human body and is received, and digests diet water paddy, and QI and blood metaplasia is not enough and it is all to become life
Disease.Symptom difference between atrophic gastritis individuality, not outer fullness and oppression in the stomach distending pain, indigestion and loss of appetite lack of appetite, heating installation is noisy, weak tired etc.
Digestive system and General Symptomies.
Content of the invention
For solving the problems, such as existing treatment stomach medicine, the invention discloses one kind has no side effect, treats stable, relapse rate
Low Chinese medicine preparation, this Chinese medicine preparation low cost, treatment acute gastritiss, chronic gastritiss, gastric ulcer, duodenal ulcer, non-
Exedens dyspepsia, cures thoroughly, evident in efficacy.
For solving the above problems, the technical solution used in the present invention is：
A kind of Chinese medicine preparation treating gastropathy, is made up of the raw material of following weight proportioning：35～45 parts of Fructus Evodiae, Hericium erinaceus (Bull. Ex Fr.) Pers.
5～10 parts of powder, 2～5 parts of Rhizoma Corydalis, 6～12 parts of Endoconcha Sepiae, 10～20 parts of Radix Salviae Miltiorrhizae, 15～25 parts of Radix Hemsleyae Macrospermae, 3～6 parts of Radix Inulae,
20～30 parts of Wasabia japonic (Euterma Wasabi), 10～16 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 3～10 parts of Radix Ophiopogonis, 2～5 parts of Radix Scutellariae, 4～8 parts of Rhizoma Schizocapsae Plantagineae, 10～20 parts of Rhizoma Cimicifugae, Pu
2～5 parts of Herba Taraxaci, 4～12 parts of Rhizoma Rodgersiae.
Preferably, being made up of the raw material of following weight proportioning：38～42 parts of Fructus Evodiae, 6～9 parts of hedgehog hydnum mycopowder, Rhizoma Corydalis
3～4 parts of rope, 8～10 parts of Endoconcha Sepiae, 12～16 parts of Radix Salviae Miltiorrhizae, 18～22 parts of Radix Hemsleyae Macrospermae, 4～5 parts of Radix Inulae, 22～27 parts of Wasabia japonic (Euterma Wasabi), in vain
12～14 parts of splendid achnatherum, 5～8 parts of Radix Ophiopogonis, 3～4 parts of Radix Scutellariae, 5～7 parts of Rhizoma Schizocapsae Plantagineae, 12～16 parts of Rhizoma Cimicifugae, 3～4 parts of Herba Taraxaci, Rhizoma Rodgersiae 6
～10 parts.
Further preferably, it is made up of the raw material of following weight proportioning：40 parts of Fructus Evodiae, 7 parts of hedgehog hydnum mycopowder, 4 parts of Rhizoma Corydalis,
9 parts of Endoconcha Sepiae, 14 parts of Radix Salviae Miltiorrhizae, 20 parts of Radix Hemsleyae Macrospermae, 4 parts of Radix Inulae, 25 parts of Wasabia japonic (Euterma Wasabi), 13 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 6 parts of Radix Ophiopogonis, 3 parts of Radix Scutellariae, paddy field
76 parts, 14 parts of Rhizoma Cimicifugae, 4 parts of Herba Taraxaci, 8 parts of Rhizoma Rodgersiae.
Wherein, the dosage form of described Chinese medicine preparation is solution, capsule, tablet or drop pill.
In addition, the preparation method of Chinese medicine preparation of the present invention, comprise the steps：
(1) Fructus Evodiae, hedgehog hydnum mycopowder, Rhizoma Corydalis, Endoconcha Sepiae are weighed by formula, Radix Salviae Miltiorrhizae adds 80% alcohol dipping 12 hours,
Reflux, extract, 4 times, 2 hours every time, filtration, filtrate merges, and decompression recycling ethanol is simultaneously concentrated into the leaching that relative density is 1.2-1.3
Cream, standby；
(2) weigh Radix Hemsleyae Macrospermae by formula, Radix Inulae, Wasabia japonic (Euterma Wasabi), the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ophiopogonis, Radix Scutellariae, Rhizoma Schizocapsae Plantagineae, Rhizoma Cimicifugae, Herba Taraxaci, Rhizoma Rodgersiae,
Add 50-90% ethanol after being ground into coarse powder, soak 3-24 hour, seepage pressure effects, united extraction liquid, decompression recycling ethanol is simultaneously dense
Shorten extractum into, add suitable quantity of water to heat 30-60 DEG C of stirring and dissolving, filter, filtrate is crossed macroporous resin column, used 5-30% ethanol elution
Impurity, then with 50-70% ethanol desorbing, collect stripping liquid, reclaim ethanol concentrate drying, dissolved with ethanol after pulverizing, filtration, filter
Liquid adds silica gel dries, and silicagel column in dry method is used ethyl acetate eluting, collected eluent, recycling design, concentrate drying must be mixed into
The extract dividing, standby；
(3) step (1) and the product of step (2) is taken to merge, heating, mix, dry, pulverize into fine powder, obtain final product；Can also
Fine powder is made further capsule, tablet, granule, soft capsule, oral liquid, soft extract, powder, pill, syrup, stream leaching
Unguentum.
The present invention is to identify and correct the principle treating according to Chinese medicine, the many doctor chiefs of collection, based on Chinese medicine to gastropathy, enteritis,
The pathogenetic understanding of cholecystitis and Therapeutic Principle, emphasis with function of spleen and stomach regulating liver and gall, dredging and pleasant machine, eliminating cold-damp disappears diet
Thinking, with reference to the achievement of pharmacological research at all times, the clinical practice through long-term diagnosis and treatment case is summarized and is formed.Gastropathy, enteritis and cholecystitis
Subordination, in digestive system disease, belongs to the categories such as the traditional Chinese medical science " stomachache ", " hypochondriac pain ", " stomachache ", " having loose bowels ".Although doctor trained in Western medicine is to this several disease
The cause of disease, pathology and diagnosis and treatment widely different, though the traditional Chinese medical science thinks that these sick causes of disease are many, its pathogeny truly has something in common,
Though disease is different, and how same the cause of disease is, according to the principle of the traditional Chinese medical science " treating different diseases with the same therapeutic principle ", all can use function of spleen and stomach regulating liver and gall in treatment, dredges
Logical and pleasant machine, eliminating cold-damp disappears the Therapeutic Principle of diet.
The medicine of the present invention be screening function of spleen and stomach regulating liver and gall, dredging and pleasant machine, eliminating cold-damp disappear diet function 15 tastes in
Medicine, is formed by theory of Chinese medical science prescription.Wherein, Fructus Evodiae acrid in the mouth heat, Return liver taste kidney, can stomach warming preventing or arresting vomiting, warming the liver sending down the abnormal ascending QI, cold expelling stop
Bitterly；Hedgehog hydnum mycopowder has soothing liver-QI stomach function regulating, effect of regulating QI to relieve pain；Rhizoma Corydalis have functions that promoting blood circulation, promoting the circulation of QI, pain relieving；Endoconcha Sepiae
There is astringing to arrest bleeding, sore；Pseudobulbus Bletillae (Rhizoma Bletillae) QI and blood regulating；Rhizoma Schizocapsae Plantagineae heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, regulating QI to relieve pain, can be effective
Preventing and treating gastric ulcer；Radix Scutellariae have cure mainly epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery, hemoptysis,
Conjunctival congestion, frequent fetal movement, hypertension, effect of carbuncle swells furuncle sore；Rhizoma Rodgersiae, bitter in the mouth, puckery, mild-natured, there are antipyretic, wind-dispelling, convergence；
Herba Taraxaci, sweet in the mouth, slight bitter, cold in nature, Return liver, stomach, there are heat-clearing and toxic substances removing, dispersing swelling and dissipating binds；Radix Salviae Miltiorrhizae, bitter in the mouth, it is slightly cold, return
The heart, Liver Channel, have the effect of promoting blood circulation to restore menstrual flow, cool blood detumescence, relieving restlessness that clears away heart-fire；Radix Ophiopogonis, sweet in the mouth, slight bitter, cold nature, GUIXIN, lung, stomach
Warp, has the effect of YIN nourishing and the production of body fluid promoting, moistening lung clears away heart-fire；Rhizoma Cimicifugae, acrid in the mouth, slight bitter, cool in nature, return lung, spleen, stomach, there is yang invigorating, deliver, thoroughly
Rash, merit of removing toxic substances effect；Radix Inulae substitutes has liver-smoothing, qi-regulating, benefiting stomach and stopping pain, anastaltic effect；Radix Hemsleyae Macrospermae has heat clearing away solution
Poison, benefiting stomach and stopping pain, can be used for having a stomachache, Peptic Ulcerss；Isothiocyanate is contained, this salt can suppress the growth of microorganism in Wasabia japonic (Euterma Wasabi),
So the acute gastritiss causing for bacterium infection, chronic gastritiss have the curative effect of thorough healing, usually take this Chinese medicine and also can make
Health product for prevention and control escherichia coli, streptococcus etc..In addition, Wasabia japonic (Euterma Wasabi) may additionally facilitate the secretion of gastric juice in itself, helps food
Digestion, thus along stomach, qi-regulating, alleviate flatulence, stomachache, etc. symptom.
Medicine of the present invention presses the principle organic assembling of monarch, synergism, and various gastral syndromes are all had relatively
Good curative effect, treating both the principal and secondary aspects of a disease, the function of the present invention is, promoting digestion and invigorating the stomach, the intestines and stomach coordinating, and anti-inflammatory and choleretic, more infectionss stop blooding, and the fat that disappears subtracts
Fertilizer, maintenance liver.Cure mainly acute gastritiss, chronic gastritiss, gastric ulcer, duodenal ulcer, gastrorrhagia, non-ulcerative digestion not
Good.The present invention is made using pure Chinese medicine, esy to use, safe and reliable, and liver, kidney, lung, stomach or spleen are all had no toxic side effect, and can grow
Phase uses.
Specific embodiment
With reference to embodiment, technical scheme is further elaborated：
Embodiment 1
A kind of Chinese medicine preparation treating gastropathy, is made up of the raw material of following weight proportioning：35 parts of Fructus Evodiae, hedgehog hydnum mycopowder 5
Part, 2 parts of Rhizoma Corydalis, 6 parts of Endoconcha Sepiae, 10 parts of Radix Salviae Miltiorrhizae, 15 parts of Radix Hemsleyae Macrospermae, 3 parts of Radix Inulae, 20 parts of Wasabia japonic (Euterma Wasabi), 10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 3 parts of Radix Ophiopogonis,
2 parts of Radix Scutellariae, 4 parts of Rhizoma Schizocapsae Plantagineae, 10 parts of Rhizoma Cimicifugae, 2 parts of Herba Taraxaci, 4 parts of Rhizoma Rodgersiae.
Embodiment 2
A kind of Chinese medicine preparation treating gastropathy, is made up of the raw material of following weight proportioning：45 parts of Fructus Evodiae, hedgehog hydnum mycopowder 10
Part, 5 parts of Rhizoma Corydalis, 12 parts of Endoconcha Sepiae, 20 parts of Radix Salviae Miltiorrhizae, 25 parts of Radix Hemsleyae Macrospermae, 6 parts of Radix Inulae, 30 parts of Wasabia japonic (Euterma Wasabi), 16 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ophiopogonis 10
Part, 5 parts of Radix Scutellariae, 8 parts of Rhizoma Schizocapsae Plantagineae, 20 parts of Rhizoma Cimicifugae, 5 parts of Herba Taraxaci, 12 parts of Rhizoma Rodgersiae.
Embodiment 3
A kind of Chinese medicine preparation treating gastropathy, is made up of the raw material of following weight proportioning：40 parts of Fructus Evodiae, hedgehog hydnum mycopowder 7
Part, 4 parts of Rhizoma Corydalis, 9 parts of Endoconcha Sepiae, 14 parts of Radix Salviae Miltiorrhizae, 20 parts of Radix Hemsleyae Macrospermae, 4 parts of Radix Inulae, 25 parts of Wasabia japonic (Euterma Wasabi), 13 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 6 parts of Radix Ophiopogonis,
3 parts of Radix Scutellariae, 6 parts of Rhizoma Schizocapsae Plantagineae, 14 parts of Rhizoma Cimicifugae, 4 parts of Herba Taraxaci, 8 parts of Rhizoma Rodgersiae.
Embodiment 4
A kind of Chinese medicine preparation treating gastropathy, is made up of the raw material of following weight proportioning：38 parts of Fructus Evodiae, hedgehog hydnum mycopowder 6
Part, 3 parts of Rhizoma Corydalis, 8 parts of Endoconcha Sepiae, 12 parts of Radix Salviae Miltiorrhizae, 18 parts of Radix Hemsleyae Macrospermae, 4 parts of Radix Inulae, 22 parts of Wasabia japonic (Euterma Wasabi), 12 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 5 parts of Radix Ophiopogonis,
3 parts of Radix Scutellariae, 5 parts of Rhizoma Schizocapsae Plantagineae, 12 parts of Rhizoma Cimicifugae, 3 parts of Herba Taraxaci, 6 parts of Rhizoma Rodgersiae.
Embodiment 5
A kind of Chinese medicine preparation treating gastropathy, is made up of the raw material of following weight proportioning：42 parts of Fructus Evodiae, hedgehog hydnum mycopowder 9
Part, 4 parts of Rhizoma Corydalis, 10 parts of Endoconcha Sepiae, 16 parts of Radix Salviae Miltiorrhizae, 22 parts of Radix Hemsleyae Macrospermae, 5 parts of Radix Inulae, 27 parts of Wasabia japonic (Euterma Wasabi), 14 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ophiopogonis 8
Part, 4 parts of Radix Scutellariae, 7 parts of Rhizoma Schizocapsae Plantagineae, 16 parts of Rhizoma Cimicifugae, 4 parts of Herba Taraxaci, 10 parts of Rhizoma Rodgersiae.
Embodiment 6
A kind of Chinese medicine preparation treating gastropathy, is made up of the raw material of following weight proportioning：45 parts of Fructus Evodiae, hedgehog hydnum mycopowder 5
Part, 5 parts of Rhizoma Corydalis, 6 parts of Endoconcha Sepiae, 10 parts of Radix Salviae Miltiorrhizae, 25 parts of Radix Hemsleyae Macrospermae, 6 parts of Radix Inulae, 20 parts of Wasabia japonic (Euterma Wasabi), 16 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 3 parts of Radix Ophiopogonis,
5 parts of Radix Scutellariae, 8 parts of Rhizoma Schizocapsae Plantagineae, 20 parts of Rhizoma Cimicifugae, 2 parts of Herba Taraxaci, 4 parts of Rhizoma Rodgersiae.
The preparation method of the Chinese medicine preparation of embodiment 1-6 comprises the steps：
(1) Fructus Evodiae, hedgehog hydnum mycopowder, Rhizoma Corydalis, Endoconcha Sepiae are weighed by formula, Radix Salviae Miltiorrhizae adds 80% alcohol dipping 12 hours,
Reflux, extract, 4 times, 2 hours every time, filtration, filtrate merges, and decompression recycling ethanol is simultaneously concentrated into the extractum that relative density is 1.2,
Standby；
(2) weigh Radix Hemsleyae Macrospermae by formula, Radix Inulae, Wasabia japonic (Euterma Wasabi), the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ophiopogonis, Radix Scutellariae, Rhizoma Schizocapsae Plantagineae, Rhizoma Cimicifugae, Herba Taraxaci, Rhizoma Rodgersiae,
Add 70% ethanol after being ground into coarse powder, soak 16 hours, seepage pressure effects, united extraction liquid, decompression recycling ethanol is simultaneously condensed into
Extractum, adds suitable quantity of water to heat 50 DEG C of stirring and dissolving, filters, filtrate crosses macroporous resin column, with 20% ethanol elution impurity, then uses
60% ethanol desorbing, collects stripping liquid, reclaims ethanol concentrate drying, is dissolved with ethanol, filtration after pulverizing, and filtrate adds silica gel and dries
Dry, silicagel column in dry method, use ethyl acetate eluting, collect eluent, recycling design, concentrate drying obtains the extraction of blending constituent
Thing, standby；
(3) step (1) and the product of step (2) is taken to merge, heating, mix, dry, pulverize into fine powder, obtain final product；Can also
Fine powder is made further capsule, tablet, granule, soft capsule, oral liquid, soft extract, powder, pill, syrup, stream leaching
Unguentum.
Clinical trial I：
To 60 Patients with Chronic Gastritis as treatment group, most of case have stomachache, abdominal distention, heartburn, acid regurgitation, nausea,
The different symptom of digestive tract of the degree such as vomiting, inappetence, through gastroscopy and pathological biopsy meet chronic gastritiss diagnosis, separately with
Diagnosis does matched group with the same period inpatient 28 of chronic gastritiss.
The Chinese medicine preparation of the embodiment of the present invention 1 is taken by treatment group, three times a day, half an hour taken with boiled water before meals.Except indivedual
Take a small amount of Chinese medicine of short-term between patient and become outside pill, during general treatment, withdraw any Pharmaceuticalss.Matched group is to Hericium Evimaccus slice (city
Sell), three times a day, four plus traditional Chinese medicine placebo Pericarpium Citri Reticulatae Massa Medicata Fermentata water or Chinese medicine (by the dialectical prescription of Chinese medicine), one daily every time, point
Secondary clothes., with 30 days for a course for the treatment of, individuals patients' symptom does not subtract and can carry out second course for the treatment of for treatment group and matched group.All cases are controlled
By supervisor's doctor's routine observation record change of illness state during treatment, the course for the treatment of terminate to carry out in latter 5 days gastroscope check and (or)
Substantially former position takes disease inspection tissue, and specimen send Pathology Deparment to check.Treatment group 15-62 days, average 34 days, matched group 20-120
My god, average 46 days.
Therapeutic outcome is：
1st, clinical efficacy：Criterion of therapeutical effect be effective, take a turn for the better, invalid three.(1) effective, clinical symptoms and sign disappear substantially
Lose or notable mitigation, food recovers normal.(2) take a turn for the better：Clinical symptoms and the most of disappearance of sign or mitigation, diet substantially increases
Plus.(3) invalid：Any improvement after clinical symptoms or sign treatment, or even increase.
According to above standard determination, treatment group：Effective 39, take a turn for the better 19, invalid 2；Matched group：Effective 9, take a turn for the better
10, no effect 9, through statistical disposition, there were significant differences.
2nd, stomach mirror image and Mucosa Biopsy change：After the course for the treatment of terminates, treatment group 60 has all done gastroscope disease inspection tissue and has cut
Piece is checked.Matched group 28 has all done gastroscope check, its 14 done simultaneously sick inspection check, its criterion of therapeutical effect divide effective, take a turn for the better,
Unchanged, increase level Four.(1) effective：Stomach mirror image has clear improvement before relatively treating, and Biopsy Gastric Mucosa major part index is different degrees of
Improvement person.(2) take a turn for the better：Stomach mirror image is improved in varying degrees before relatively treating, the Biopsy Gastric Mucosa part index number person of taking a favorable turn.(3) no
Effect：Stomach mirror image and disease inspection indices relatively treat front no any progressive person.(4) increase：Adding occur in stomach mirror image and Biopsy Gastric Mucosa
Change tendency person again.Review result, effective 34 for the treatment of group, take a turn for the better 6, no effect 9, increases 1.Effective 6 of matched group, takes a turn for the better
5, no effect 9, increases 8.It is statistically analyzed that there were significant differences.
A kind of Chinese medicine preparation of gastropathy and preparation method thereof for the treatment of above the invention being implemented to be provided is carried out
Detailed introduction, for one of ordinary skill in the art, according to the thought of the invention embodiment, in specific embodiment
And all will change in range of application, in sum, this specification content should not be construed as the restriction to the invention.
Claims (5)
1. a kind of Chinese medicine preparation treating gastropathy is it is characterised in that be made up of the raw material of following weight proportioning：Fructus Evodiae 35～45
Part, 5～10 parts of hedgehog hydnum mycopowder, 2～5 parts of Rhizoma Corydalis, 6～12 parts of Endoconcha Sepiae, 10～20 parts of Radix Salviae Miltiorrhizae, 15～25 parts of Radix Hemsleyae Macrospermae, building
Fragrant 3～6 parts, 20～30 parts of Wasabia japonic (Euterma Wasabi), 10～16 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 3～10 parts of Radix Ophiopogonis, 2～5 parts of Radix Scutellariae, 4～8 parts of Rhizoma Schizocapsae Plantagineae, Rhizoma Cimicifugae 10
～20 parts, 2～5 parts of Herba Taraxaci, 4～12 parts of Rhizoma Rodgersiae.
2. Chinese medicine preparation as claimed in claim 1 is it is characterised in that be made up of the raw material of following weight proportioning：Fructus Evodiae 38
～42 parts, 6～9 parts of hedgehog hydnum mycopowder, 3～4 parts of Rhizoma Corydalis, 8～10 parts of Endoconcha Sepiae, 12～16 parts of Radix Salviae Miltiorrhizae, 18～22 parts of Radix Hemsleyae Macrospermae, soil
4～5 parts of the Radix Aucklandiae, 22～27 parts of Wasabia japonic (Euterma Wasabi), 12～14 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae), 5～8 parts of Radix Ophiopogonis, 3～4 parts of Radix Scutellariae, 5～7 parts of Rhizoma Schizocapsae Plantagineae, Rhizoma Cimicifugae
12～16 parts, 3～4 parts of Herba Taraxaci, 6～10 parts of Rhizoma Rodgersiae.
3. Chinese medicine preparation as claimed in claim 2 is it is characterised in that be made up of the raw material of following weight proportioning：Fructus Evodiae 40
Part, 7 parts of hedgehog hydnum mycopowder, 4 parts of Rhizoma Corydalis, 9 parts of Endoconcha Sepiae, 14 parts of Radix Salviae Miltiorrhizae, 20 parts of Radix Hemsleyae Macrospermae, 4 parts of Radix Inulae, 25 parts of Wasabia japonic (Euterma Wasabi), the Pseudobulbus Bletillae (Rhizoma Bletillae)
13 parts, 6 parts of Radix Ophiopogonis, 3 parts of Radix Scutellariae, 6 parts of Rhizoma Schizocapsae Plantagineae, 14 parts of Rhizoma Cimicifugae, 4 parts of Herba Taraxaci, 8 parts of Rhizoma Rodgersiae.
4. the Chinese medicine preparation as described in any one of claim 1-3 it is characterised in that described Chinese medicine preparation dosage form be solution,
Capsule, tablet or drop pill.
5. the preparation method of the Chinese medicine preparation according to any one of claim 1-3 is it is characterised in that comprise the steps：
(1) Fructus Evodiae, hedgehog hydnum mycopowder, Rhizoma Corydalis, Endoconcha Sepiae are weighed by formula, Radix Salviae Miltiorrhizae adds 80% alcohol dipping 12 hours, backflow
Extract 4 times, 2 hours every time, filter, filtrate merges, decompression recycling ethanol is simultaneously concentrated into the extractum that relative density is 1.2-1.3,
Standby；
(2) weigh Radix Hemsleyae Macrospermae, Radix Inulae, Wasabia japonic (Euterma Wasabi), the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Ophiopogonis, Radix Scutellariae, Rhizoma Schizocapsae Plantagineae, Rhizoma Cimicifugae, Herba Taraxaci, Rhizoma Rodgersiae by formula, pulverize
Add 50-90% ethanol after becoming coarse powder, soak 3-24 hour, seepage pressure effects, united extraction liquid, decompression recycling ethanol is simultaneously condensed into
Extractum, adds suitable quantity of water to heat 30-60 DEG C of stirring and dissolving, filters, filtrate crosses macroporous resin column, miscellaneous with 5-30% ethanol elution
Matter, then with 50-70% ethanol desorbing, collect stripping liquid, reclaim ethanol concentrate drying, dissolved with ethanol after pulverizing, filtration, filtrate
Plus silica gel drying, silicagel column in dry method, use ethyl acetate eluting, collect eluent, recycling design, concentrate drying obtains blending constituent
Extract, standby；
(3) step (1) and the product of step (2) is taken to merge, heating, mix, dry, pulverize into fine powder, obtain final product；Can also carefully
Powder makes capsule, tablet, granule, soft capsule, oral liquid, soft extract, powder, pill, syrup, fluid extract further
Agent.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1189366A (en) * | 1997-01-29 | 1998-08-05 | 唐贵贤 | Gastritis pills |
| CN101874874A (en) * | 2010-07-01 | 2010-11-03 | 夏黎明 | Chinese medicinal preparation for treating helicobacter pylori concerned chronic gastritis and preparation method thereof |
| CN102274401A (en) * | 2011-06-30 | 2011-12-14 | 贵州三仁堂药业有限公司 | Traditional Chinese medicine preparation for treating gastropathy and preparation method and detection method thereof |
| CN104107315A (en) * | 2014-04-06 | 2014-10-22 | 王悦阳 | Panax Notoginseng gastritis treatment pill |
-
2016
- 2016-12-20 CN CN201611182336.XA patent/CN106421409A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1189366A (en) * | 1997-01-29 | 1998-08-05 | 唐贵贤 | Gastritis pills |
| CN101874874A (en) * | 2010-07-01 | 2010-11-03 | 夏黎明 | Chinese medicinal preparation for treating helicobacter pylori concerned chronic gastritis and preparation method thereof |
| CN102274401A (en) * | 2011-06-30 | 2011-12-14 | 贵州三仁堂药业有限公司 | Traditional Chinese medicine preparation for treating gastropathy and preparation method and detection method thereof |
| CN104107315A (en) * | 2014-04-06 | 2014-10-22 | 王悦阳 | Panax Notoginseng gastritis treatment pill |
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Application publication date: 20170222 |