CN103520395A - Traditional Chinese medicine composition for treating lung cancer - Google Patents
Traditional Chinese medicine composition for treating lung cancer Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating lung cancer. The traditional Chinese medicine composition for treating the lung cancer is prepared from the following medicinal raw materials by weight: 9-20g of sculellaria barbata, 3-10g of dahurian patrinia herb, 9-20g of nightshade, 9-20g of fructus forsythiae, 3-10g of fiveleaf akebia fruit, 3-10g of dysosma versipellis, 3-10g of selaginella doederleinii hieron, 3-10g of folium cycas, 9-20g of poria cocos, 5-20g of bighead atractylodes rhizome, 5-20g of codonopsis pilosula and 3-20g of wolfberry fruit. The traditional Chinese medicine composition for treating the lung cancer has the beneficial effects that poria cocos, codonopsis pilosula, bighead atractylodes rhizome and wolfberry fruit are combined so as to achieve the effects of strengthening healthy energy and enhancing efficacy, improve the immunity of the organism and reduce the toxic and side effect; sculellaria barbata, dahurian patrinia herb, nightshade, fructus forsythiae, fiveleaf akebia fruit, dysosma versipellis, selaginella doederleinii hieron and folium cycas have the effects of clearing heat and removing toxicity without damaging the lung and are capable of inhibiting the growth of tumors and effectively killing tumor cells.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of pulmonary carcinoma.
Background technology
Pulmonary carcinoma is the highest cancer of world today's mortality rate, it is clinical take cough, uncomfortable in chest, chest pain, generate heat, breathe hard as cardinal symptom, expectoration is rare or thick, even expectoration is with the blood streak or hemoptysis and occur with constipation symptom.The advantage of western medical treatment is instant effect, but normal because over-treatment causes the adverse consequences that things turn out contrary to one's wishes, and side effect severe patient can cause single system or multisystem nonfunction.Advantages of TCM is the successful of relief of symptoms, and to the secondary in the middle of carcinosis radiotherapy and chemotherapy, iatrogenic infringement has good auxiliary therapeutic action, can treat for cause of disease.
In prior art, the herbal species for the treatment of pulmonary carcinoma is a lot, for example application number is 200910102870.9, and name is called the Chinese medicine of treat pulmonary carcinoma, its raw material by Rhizoma Coptidis, the Rhizoma Anemarrhenae, Euphorbia chrysocoma Levl.et Vant., Rhizoma Curcumae Longae, bamboo root Huang, Scolopendra, golden scorpion, roll mountain pearl, thousand worms enough etc. 9 taste medical materials form; Application number is 201210086685.7, name is called Chinese medicine and the application thereof for the treatment of pulmonary carcinoma, and raw material is comprised of 18 taste Chinese crude drugs such as Bufo siccus, Scolopendra, Gekko Swinhonis, the Radix Astragali, Radix Codonopsis, Fructus Lycii, the Rhizoma Atractylodis Macrocephalae, the Rhizoma Atractylodis Macrocephalae, Periostracum Cicadae, Pheretima, Spica Prunellae, Radix Notoginseng powder, Olibanum, Myrrha, Herba Hedyotidis Diffusae, Fructus Ligustri Lucidi, Moschus, Radix Platycodoniss; Application number is 201210476145.X, name is called a kind of patent application for the treatment of the Chinese medicine composition of pulmonary carcinoma, and its medicine is made by the Radix Astragali, Herba Solani Lyrati, Fructus Akebiae, Bulbus Fritillariae Cirrhosae, Herba Scutellariae Barbatae, Poria, Bulbus Lilii, Radix Platycodonis, Herba Houttuyniae, Gekko Swinhonis, Cordyceps, Hirudo, the Radix Stemonae, Bungarus Parvus, Radix Glehniae and 16 kinds of Chinese medicines of Radix Sophorae Tonkinensis.From upper example, can find out, the medicine of existing treatment pulmonary carcinoma, raw material variety is various mostly, and preparation technology is comparatively complicated, adds that some raw material is rare valuable medicinal, and to cause the price of medicine higher, patient is difficult to bear.In addition, because some crude drug itself just has very large toxicity, to cause medicine with certain toxicity, often patient is produced to certain side effect.At present, there is no the medicine with same materials compatibility of the present invention.
Summary of the invention
Object of the present invention is exactly, in order to address the above problem, to provide a kind of Chinese medicine composition for the treatment of pulmonary carcinoma, and it has, and good effect, expense are low, the advantage such as have no side effect.
To achieve these goals, the present invention adopts following technical scheme:
A kind of Chinese medicine composition for the treatment of pulmonary carcinoma, crude drug by following weight forms: Herba Scutellariae Barbatae 9-20 gram, Herba Patriniae 3-10 gram, Herba Solani Nigri 9-20 gram, Fructus Forsythiae 9-20 gram, Fructus Akebiae 3-10 gram, Radix et Rhizoma Dysosmatis 3-10 gram, Herba Selaginellae Doederleinii 3-10 gram, Folium cordylines fruticosae 3-10 gram, Poria 9-20 gram, Rhizoma Atractylodis Macrocephalae 5-20 gram, Radix Codonopsis 5-20 gram, Fructus Lycii 3-20 gram.
Preferably, a kind of Chinese medicine composition for the treatment of pulmonary carcinoma, crude drug by following weight forms: Herba Scutellariae Barbatae 10-18 gram, Herba Patriniae 4-8 gram, Herba Solani Nigri 11-17 gram, Fructus Forsythiae 10-18 gram, Fructus Akebiae 5-9 gram, Radix et Rhizoma Dysosmatis 5-10 gram, Herba Selaginellae Doederleinii 5-8 gram, Folium cordylines fruticosae 3-8 gram, Poria 12-20 gram, Rhizoma Atractylodis Macrocephalae 10-20 gram, Radix Codonopsis 10-18 gram, Fructus Lycii 5-18 gram.
More preferred, a kind of Chinese medicine composition for the treatment of pulmonary carcinoma, crude drug by following weight forms: 16 grams of Herba Scutellariae Barbataes, 7 grams of Herba Patriniae, 15 grams of Herba Solani Nigris, 16 grams of Fructus Forsythiaes, 8 grams of Fructus Akebiaes, 8 grams of Radix et Rhizoma Dysosmatiss, 7 grams of Herba Selaginellae Doederleiniis, 5 grams of Folium cordylines fruticosaes, 18 grams, Poria, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 16 grams of Radix Codonopsis, 16 grams of Fructus Lycii.
Why pulmonary carcinoma forms, and is that pathogen is taken advantage of a weak point because of positive QI-insufficiency, and long-pending one-tenth also.Healthy energy comprises several aspects such as gas, blood, yin, yang, and positive QI-insufficiency is weak, no matter is that whole weakness or a certain internal organs are weak, is all the prerequisite of tumor formation and development.From the angle of prevention, people should constantly note protection, foster healthy energy, and from the angle for the treatment of, certain positive QI-insufficiency, answers tonification, helps certain healthy energy, eliminates paathogenic factor simultaneously, i.e. " righting method is evil ".
The pharmacological action of each component is as follows:
Herba Scutellariae Barbatae: cool in nature, mildly bitter flavor.Return lung, liver, kidney channel.Tool heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the function such as anticancer.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, edema, jaundice.
Herba Patriniae: acrid in the mouth, hardship, be slightly cold.Return liver, stomach, large intestine channel.Heat-clearing and toxic substances removing, removing heat from blood, eliminating carbuncle evacuation of pus, stasis-dispelling and pain-killing.For acute appendicitis, the high heat of lung abscess, coughs vomiting bloody pus, pyretic toxicity skin ulcer furuncle, and furuncle is bitterly swollen, breast abdomen pain, appendicitis, enteritis, dysentery, puerperal abdonimal pain, dysmenorrhea.
Herba Solani Nigri: cold in nature, bitter in the mouth, micro-sweet; Slightly poisonous.Heat-clearing and toxic substances removing, promoting blood circulation and detumescence.Heat clearing away, removing toxic substances, invigorates blood circulation, detumescence.Control furuncle, carbuncle, erysipelas, osteopatia sprain, chronic tracheitis, acute nephritis.For sore and toxic, skin eczema, dysuria, chronic senile tracheitis, leukorrhagia, prostatitis, dysentery, cat fever, toothache, urinary system infection, mastitis, leucorrhea, cancer; Carbuncle furuncle furuncle, pemphigus, injury from falling down, venom are controlled in external.。
Fructus Forsythiae: Chinese medicine bitter in the mouth, cold nature.Heat-clearing and toxic substances removing, mass dissipating and swelling eliminating.Mongolian medicine bitter in the mouth, cool in nature." association day " clearly, antidiarrheal.Chinese medicine is controlled calentura from the beginning of, anemopyretic cold, and heating is vexed, laryngopharynx swelling and pain, macule, erysipelas, scrofula, carbuncle pyogenic infections from tumour or sore, acute nephritis, pyretic stranguria.The mongolian medicine subcutaneous ulcer of harnessing the Yellow River, intestinal twinge, " association day " disease, intestinal heat.
Fructus Akebiae: bitter in the mouth, cold in nature.Return liver, spleen channel.There is liver-smoothing, qi-regulating, the effect of removing obstruction for relieving pain.Cure mainly: tumor and the cancerous pain such as hepatocarcinoma, gastric cancer, pulmonary carcinoma, breast carcinoma.
Radix et Rhizoma Dysosmatis: bitter in the mouth; Pungent; Cool in nature; Poisonous.Lung; Liver Channel.Dissipating phlegm and resolving masses; Stasis-dispelling and pain-killing; Heat-clearing and toxic substances removing.For cough; Laryngopharynx swelling and pain; Scrofula; Goiter; Carbuncle; Furuncle; Venom; Traumatic injury; Arthromyodynia.
Herba Selaginellae Doederleinii: Zhang Zhongqian report, forms compound treatment Senile Advanced primary lung cancer 34 examples, four types such as minute qi-deficiency type, YIN-deficiency type, type of deficiency of both QI and YIN and the hot stasis-toxin type of expectorant with anticarcinogens such as Herba Selaginellae Doederleiniis, dialectical plus-minus, treats result 4 months: partial rcsponse 1 example, stablize 30 examples, worsen 3 examples; 1 year 27 example of surviving, 1 year above 6 example, 2 years above 1 examples; Dead 6 examples.Clinical treatment presentation of results also can be obtained good therapeutic effect by treatment by Chinese herbs pulmonary carcinoma merely.
Folium cordylines fruticosae: heat clearing away, hemostasis, dissipating blood stasis.Control dysentery, spit blood, have blood in stool, stomachache, hematuria, menorrhagia, treating swelling and pain by traumatic injury.
Poria: sweet in the mouth, light, property are flat.Enter the heart, lung, spleen channel.The function with promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach, dampness diuretic; Reduce phlegm, hidroschesis; Antiabortive; Increase appetite.The vitamin A that the Rhizoma Atractylodis Macrocephalae contains volatile oil, atractylol, Rhizoma Atractylodis ketone and health had to benefiting action.
Radix Codonopsis: property is flat, sweet in the mouth, micro-acid.Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Fructus Lycii: its sweet in the mouth, the flat effect with the liver and the kidney tonifying of property, in Compendium of Material Medica, say and " take for a long time hard muscles and bones, make light of one's life by commiting suicide not old, cold-resistant summer-heat." traditional Chinese medical science conventional it treat hepatic and renal YIN deficiency, soreness of the waist and knees, dizziness, forgetful, dizzy, the many tear of blurred vision, quench one's thirst, the disease such as seminal emission.Modern pharmacology studies confirm that Fructus Lycii scalable body's immunity, can effectively suppress tumor growth and cell mutation, has slow down aging, the effect of anti-fatty liver, adjusting blood fat and the aspect such as blood glucose, energy, and is applied to clinical.
Beneficial effect of the present invention: Poria, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Fructus Lycii four medicines merge, and have the effect of Fuzheng Zengxiao, can improve immunity of organisms, reduce toxic and side effects; Herba Scutellariae Barbatae, Herba Patriniae, Herba Solani Nigri, Fructus Forsythiae, Fructus Akebiae, Radix et Rhizoma Dysosmatis, Herba Selaginellae Doederleinii, Folium cordylines fruticosae heat-clearing and toxic substances removing and non-impairing the lung can suppress tumor to grow up, effectively kill tumor cell.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described; but be not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various modifications that creative work can make or distortion still in protection scope of the present invention.
Embodiment 1:
A kind of Chinese medicine composition for the treatment of pulmonary carcinoma, crude drug by following weight forms: 9 grams of Herba Scutellariae Barbataes, 3 grams of Herba Patriniae, 9 grams of Herba Solani Nigris, 9 grams of Fructus Forsythiaes, 3 grams of Fructus Akebiaes, 3 grams of Radix et Rhizoma Dysosmatiss, 3 grams of Herba Selaginellae Doederleiniis, 3 grams of Folium cordylines fruticosaes, 9 grams, Poria, 5 grams of the Rhizoma Atractylodis Macrocephalaes, 5 grams of Radix Codonopsis, 3 grams of Fructus Lycii.
Above-mentioned medical material is put into marmite, add the water soaking 2 hours of 4 times of doses, after water is boiled, with slow fire boiling 1 hour, filtering liquid medicine, can take.
Embodiment 2:
A kind of Chinese medicine composition for the treatment of pulmonary carcinoma, crude drug by following weight forms: 20 grams of Herba Scutellariae Barbataes, 10 grams of Herba Patriniae, 20 grams of Herba Solani Nigris, 20 grams of Fructus Forsythiaes, 10 grams of Fructus Akebiaes, 10 grams of Radix et Rhizoma Dysosmatiss, 10 grams of Herba Selaginellae Doederleiniis, 10 grams of Folium cordylines fruticosaes, 20 grams, Poria, 20 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Radix Codonopsis, 20 grams of Fructus Lycii.
Above-mentioned medical material is put into marmite, add the water soaking 2 hours of 4 times of doses, after water is boiled, with slow fire boiling 1 hour, filtering liquid medicine, can take.
Embodiment 3:
A kind of Chinese medicine composition for the treatment of pulmonary carcinoma, crude drug by following weight forms: 16 grams of Herba Scutellariae Barbataes, 7 grams of Herba Patriniae, 15 grams of Herba Solani Nigris, 16 grams of Fructus Forsythiaes, 8 grams of Fructus Akebiaes, 8 grams of Radix et Rhizoma Dysosmatiss, 7 grams of Herba Selaginellae Doederleiniis, 5 grams of Folium cordylines fruticosaes, 18 grams, Poria, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 16 grams of Radix Codonopsis, 16 grams of Fructus Lycii.
Above-mentioned medical material is put into marmite, add the water soaking 2 hours of 4 times of doses, after water is boiled, with slow fire boiling 1 hour, filtering liquid medicine, can take.
Clinical data:
1, physical data
Through histopathology and cytolgical examination, be diagnosed as patients with advanced NSCLC, the age is between 32-65; Important organ function of organization normal.The patient who meets this research inclusion criteria is 100 examples.Man's 55 examples, female's 45 examples, 56.21 years old mean age.
2, Western medicine diagnose standard
Specified standard in " Chinese common cancer diagnosis and treatment standard " that Department of Medical Administration of Diagnosis of Non-Small Cell Lung standard employing Ministry of Health of the People's Republic of China writes.
Tcm diagnosis standard
With reference to Ministry of Public Health " new Chinese medicine guideline of clinical investigations " (2002 editions), formulate, distinguish as accumulateing disease in ecchymosis: cough, out of breath, chest pain, expectorant Huang or expectorant blood are dark red, can be with low grade fever, purplish tongue or have petechia, ecchymosis, yellow and thin fur, hesitant pulse or stringy and thready pulse.
3, Therapeutic Method
Be decocted in water for oral dose, the potion embodiment of the present invention 3 Chinese medicine compositions, divided and sooner or later took for twice every day, within 1 week, were a course for the treatment of.
4, criterion of therapeutical effect
Clinical disease criterion of therapeutical effect by cough, cough up phlegm, the common sympton such as expectorant blood, uncomfortable in chest, chest pain, out of breath, heating by light, in, be heavily divided into 3 grades (with reference to Ministry of Public Health " new Chinese medicine guideline of clinical investigations "), be designated as respectively 2,4,6 minutes, before and after treatment, accumulate contrast, press integration than method Estimating curative effect.Effective: after treatment, symptom and sign integrated value declines >=2/3; Effective: after treatment, symptom and sign integrated value declines >=1/3, but ﹤ 2/3; Invalid: not reach effective standard person.
5, therapeutic effect
Clinical observation patients with lung cancer 100 examples, fill a prescription and treat after 4 courses for the treatment of through the present invention, and disease is improved effective 40 examples, effective 48 examples, effective percentage 88%.
Claims (3)
1. a Chinese medicine composition for the treatment of pulmonary carcinoma, it is characterized in that, crude drug by following weight forms: Herba Scutellariae Barbatae 9-20 gram, Herba Patriniae 3-10 gram, Herba Solani Nigri 9-20 gram, Fructus Forsythiae 9-20 gram, Fructus Akebiae 3-10 gram, Radix et Rhizoma Dysosmatis 3-10 gram, Herba Selaginellae Doederleinii 3-10 gram, Folium cordylines fruticosae 3-10 gram, Poria 9-20 gram, Rhizoma Atractylodis Macrocephalae 5-20 gram, Radix Codonopsis 5-20 gram, Fructus Lycii 3-20 gram.
2. a kind of Chinese medicine composition for the treatment of pulmonary carcinoma as claimed in claim 1, crude drug by following weight forms: Herba Scutellariae Barbatae 10-18 gram, Herba Patriniae 4-8 gram, Herba Solani Nigri 11-17 gram, Fructus Forsythiae 10-18 gram, Fructus Akebiae 5-9 gram, Radix et Rhizoma Dysosmatis 5-10 gram, Herba Selaginellae Doederleinii 5-8 gram, Folium cordylines fruticosae 3-8 gram, Poria 12-20 gram, Rhizoma Atractylodis Macrocephalae 10-20 gram, Radix Codonopsis 10-18 gram, Fructus Lycii 5-18 gram.
3. a kind of Chinese medicine composition for the treatment of pulmonary carcinoma as claimed in claim 1, it is characterized in that, crude drug by following weight forms: 16 grams of Herba Scutellariae Barbataes, 7 grams of Herba Patriniae, 15 grams of Herba Solani Nigris, 16 grams of Fructus Forsythiaes, 8 grams of Fructus Akebiaes, 8 grams of Radix et Rhizoma Dysosmatiss, 7 grams of Herba Selaginellae Doederleiniis, 5 grams of Folium cordylines fruticosaes, 18 grams, Poria, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 16 grams of Radix Codonopsis, 16 grams of Fructus Lycii.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104523740A (en) * | 2014-12-04 | 2015-04-22 | 福建医科大学 | Method for preparing selaginella doederleinii hieron polysaccharide extract product and application thereof |
| CN104524374A (en) * | 2014-12-30 | 2015-04-22 | 潘振奎 | Traditional Chinese medicine formula for treating lung cancer and preparation method of traditional Chinese medicine formula |
| CN105596845A (en) * | 2016-01-26 | 2016-05-25 | 宋秀磊 | Traditional Chinese medicine combination for treating lung cancer |
| CN105596915A (en) * | 2015-12-31 | 2016-05-25 | 崔鹏 | Traditional Chinese medicine composition for treating lung cancer |
| CN105853618A (en) * | 2016-04-14 | 2016-08-17 | 黑龙江中医药大学 | Traditional Chinese medicine composition with broad-spectrum anti-cancer effect as well as preparation method and application thereof |
| CN106214707A (en) * | 2016-11-04 | 2016-12-14 | 谭淞文 | A kind of method of Folium cordylines fruticosae among the people treatment cancer |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101491663A (en) * | 2009-02-26 | 2009-07-29 | 杨杰生 | Traditional Chinese medicine composition for treating various cancer |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101491663A (en) * | 2009-02-26 | 2009-07-29 | 杨杰生 | Traditional Chinese medicine composition for treating various cancer |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104523740A (en) * | 2014-12-04 | 2015-04-22 | 福建医科大学 | Method for preparing selaginella doederleinii hieron polysaccharide extract product and application thereof |
| CN104523740B (en) * | 2014-12-04 | 2017-08-25 | 福建医科大学 | A kind of selaginella doederlleini polyoses extract preparation method and applications |
| CN104524374A (en) * | 2014-12-30 | 2015-04-22 | 潘振奎 | Traditional Chinese medicine formula for treating lung cancer and preparation method of traditional Chinese medicine formula |
| CN105596915A (en) * | 2015-12-31 | 2016-05-25 | 崔鹏 | Traditional Chinese medicine composition for treating lung cancer |
| CN105596845A (en) * | 2016-01-26 | 2016-05-25 | 宋秀磊 | Traditional Chinese medicine combination for treating lung cancer |
| CN105853618A (en) * | 2016-04-14 | 2016-08-17 | 黑龙江中医药大学 | Traditional Chinese medicine composition with broad-spectrum anti-cancer effect as well as preparation method and application thereof |
| CN106214707A (en) * | 2016-11-04 | 2016-12-14 | 谭淞文 | A kind of method of Folium cordylines fruticosae among the people treatment cancer |
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