CN103520395B - Traditional Chinese medicine composition for treating lung cancer - Google Patents
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Abstract
The invention discloses a traditional Chinese medicine composition for treating lung cancer. The traditional Chinese medicine composition for treating the lung cancer is prepared from the following medicinal raw materials by weight: 9-20g of sculellaria barbata, 3-10g of dahurian patrinia herb, 9-20g of nightshade, 9-20g of fructus forsythiae, 3-10g of fiveleaf akebia fruit, 3-10g of dysosma versipellis, 3-10g of selaginella doederleinii hieron, 3-10g of folium cycas, 9-20g of poria cocos, 5-20g of bighead atractylodes rhizome, 5-20g of codonopsis pilosula and 3-20g of wolfberry fruit. The traditional Chinese medicine composition for treating the lung cancer has the beneficial effects that poria cocos, codonopsis pilosula, bighead atractylodes rhizome and wolfberry fruit are combined so as to achieve the effects of strengthening healthy energy and enhancing efficacy, improve the immunity of the organism and reduce the toxic and side effect; sculellaria barbata, dahurian patrinia herb, nightshade, fructus forsythiae, fiveleaf akebia fruit, dysosma versipellis, selaginella doederleinii hieron and folium cycas have the effects of clearing heat and removing toxicity without damaging the lung and are capable of inhibiting the growth of tumors and effectively killing tumor cells.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition for the treatment of pulmonary carcinoma.
Background technology
Pulmonary carcinoma is the cancer that world today's mortality rate is the highest, its clinical with cough, uncomfortable in chest, chest pain, generate heat, breathe hard as cardinal symptom, expectoration is rare or thick, and even expectoration occurs with constipation symptom with the blood streak or hemoptysis.The advantage of western medical treatment is instant effect, but often causes because of over-treatment the adverse consequences that things turn out contrary to one's wishes, and side effect severe patient can cause single system or multisystem nonfunction.Advantages of TCM is the successful of relief of symptoms, has good auxiliary therapeutic action, can treat for cause of disease the iatrogenic infringement of the secondary in the middle of carcinosis radiotherapy and chemotherapy.
In prior art, the herbal species for the treatment of pulmonary carcinoma is a lot, such as application number is 200910102870.9, and name is called the Chinese medicine for the treatment of pulmonary carcinoma, its raw material by Rhizoma Coptidis, the Rhizoma Anemarrhenae, Euphorbia chrysocoma Levl.et Vant., Rhizoma Curcumae Longae, bamboo root Huang, Scolopendra, golden scorpion, roll mountain pearl, thousand worms enough etc. 9 taste medical materials form; Application number is 201210086685.7, name is called Chinese medicine and the application thereof for the treatment of pulmonary carcinoma, and raw material is made up of 18 taste Chinese crude drugs such as Bufo siccus, Scolopendra, Gekko Swinhonis, the Radix Astragali, Radix Codonopsis, Fructus Lycii, the Rhizoma Atractylodis Macrocephalae, the Rhizoma Atractylodis Macrocephalae, Periostracum Cicadae, Pheretima, Spica Prunellae, Radix Notoginseng powder, Olibanum, Myrrha, Herba Hedyotidis Diffusae, Fructus Ligustri Lucidi, Moschus, Radix Platycodoniss; Application number is 201210476145.X, name is called a kind of patent application for the treatment of the Chinese medicine composition of pulmonary carcinoma, and its medicine is made up of the Radix Astragali, Herba Solani Lyrati, Fructus Akebiae, Bulbus Fritillariae Cirrhosae, Herba Scutellariae Barbatae, Poria, Bulbus Lilii, Radix Platycodonis, Herba Houttuyniae, Gekko Swinhonis, Cordyceps, Hirudo, the Radix Stemonae, Bungarus Parvus, Radix Glehniae and Radix Sophorae Tonkinensis 16 kinds of Chinese medicines.As can be seen from upper example, the medicine of existing treatment pulmonary carcinoma, most raw material variety is various, and preparation technology is comparatively complicated, and add that some raw material is rare valuable medicinal, to cause the price of medicine higher, patient is difficult to bear.In addition, because some crude drug inherently has very large toxicity, to cause medicine with certain toxicity, often certain side effect is produced to patient.At present, there is no the medicine with same materials compatibility of the present invention.
Summary of the invention
Object of the present invention is exactly to solve the problem, and provides a kind of Chinese medicine composition for the treatment of pulmonary carcinoma, and it has, and good effect, expense are low, the advantage such as have no side effect.
To achieve these goals, the present invention adopts following technical scheme:
A kind of Chinese medicine composition for the treatment of pulmonary carcinoma, be made up of the crude drug of following weight: Herba Scutellariae Barbatae 9-20 gram, Herba Patriniae 3-10 gram, Herba Solani Nigri 9-20 gram, Fructus Forsythiae 9-20 gram, Fructus Akebiae 3-10 gram, Radix et Rhizoma Dysosmatis 3-10 gram, Herba Selaginellae Doederleinii 3-10 gram, Folium cordylines fruticosae 3-10 gram, Poria 9-20 gram, Rhizoma Atractylodis Macrocephalae 5-20 gram, Radix Codonopsis 5-20 gram, Fructus Lycii 3-20 gram.
Preferably, a kind of Chinese medicine composition for the treatment of pulmonary carcinoma, be made up of the crude drug of following weight: Herba Scutellariae Barbatae 10-18 gram, Herba Patriniae 4-8 gram, Herba Solani Nigri 11-17 gram, Fructus Forsythiae 10-18 gram, Fructus Akebiae 5-9 gram, Radix et Rhizoma Dysosmatis 5-10 gram, Herba Selaginellae Doederleinii 5-8 gram, Folium cordylines fruticosae 3-8 gram, Poria 12-20 gram, Rhizoma Atractylodis Macrocephalae 10-20 gram, Radix Codonopsis 10-18 gram, Fructus Lycii 5-18 gram.
More preferred, a kind of Chinese medicine composition for the treatment of pulmonary carcinoma, be made up of the crude drug of following weight: Herba Scutellariae Barbatae 16 grams, Herba Patriniae 7 grams, Herba Solani Nigri 15 grams, Fructus Forsythiae 16 grams, Fructus Akebiae 8 grams, Radix et Rhizoma Dysosmatis 8 grams, Herba Selaginellae Doederleinii 7 grams, Folium cordylines fruticosae 5 grams, 18 grams, Poria, the Rhizoma Atractylodis Macrocephalae 15 grams, Radix Codonopsis 16 grams, Fructus Lycii 16 grams.
Why pulmonary carcinoma is formed, and be that pathogen is taken advantage of a weak point because positive QI-insufficiency, long-pending one-tenth also.Healthy energy comprises several aspects such as gas, blood, yin, yang, and positive QI-insufficiency is then weak, and no matter being that overall weakness or a certain internal organs are weak, is all the prerequisite of tumor formation and development.From the angle of prevention, people should note protection the moment, foster healthy energy, and from the angle for the treatment of, certain positive QI-insufficiency, then answer tonification, help certain healthy energy, eliminate paathogenic factor simultaneously, i.e. " righting method is evil ".
The pharmacological action of each component is as follows:
Herba Scutellariae Barbatae: cool in nature, mildly bitter flavor.Return lung, liver, kidney channel.Tool heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the function such as anticancer.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, edema, jaundice.
Herba Patriniae: acrid in the mouth, hardship, be slightly cold.Return liver, stomach, large intestine channel.Heat-clearing and toxic substances removing, removing heat from blood, eliminating carbuncle evacuation of pus, stasis-dispelling and pain-killing.For acute appendicitis, the high heat of lung abscess, coughs vomiting bloody pus, pyretic toxicity skin ulcer furuncle, and furuncle pain is swollen, breast abdomen pain, appendicitis, enteritis, dysentery, puerperal abdonimal pain, dysmenorrhea.
Herba Solani Nigri: cold in nature, bitter in the mouth, micro-sweet; Slightly poisonous.Heat-clearing and toxic substances removing, promoting blood circulation and detumescence.Heat clearing away, removing toxic substances, invigorates blood circulation, detumescence.Control furuncle, carbuncle, erysipelas, osteopatia sprain, chronic tracheitis, acute nephritis.For sore and toxic, skin eczema, dysuria, chronic senile tracheitis, leukorrhagia, prostatitis, dysentery, cat fever, toothache, urinary system infection, mastitis, leucorrhea, cancer; Carbuncle furuncle furuncle is controlled in external, pemphigus, injury from falling down, venom.。
Fructus Forsythiae: Chinese medicine bitter in the mouth, cold nature.Heat-clearing and toxic substances removing, mass dissipating and swelling eliminating.Mongolian medicine bitter in the mouth, cool in nature.Clearly " association's day ", antidiarrheal.Chinese medicine controls calentura from the beginning of, anemopyretic cold, and heating is vexed, laryngopharynx swelling and pain, macule, erysipelas, scrofula, carbuncle pyogenic infections from tumour or sore, acute nephritis, pyretic stranguria.Mongolian medicine is harnessed the Yellow River subcutaneous ulcer, intestinal twinge, and " association's day " is sick, intestinal heat.
Fructus Akebiae: bitter in the mouth, cold in nature.Return liver, spleen channel.There is liver-smoothing, qi-regulating, effect of removing obstruction for relieving pain.Cure mainly: tumor and the cancerous pain such as hepatocarcinoma, gastric cancer, pulmonary carcinoma, breast carcinoma.
Radix et Rhizoma Dysosmatis: bitter in the mouth; Pungent; Cool in nature; Poisonous.Lung; Liver Channel.Dissipating phlegm and resolving masses; Stasis-dispelling and pain-killing; Heat-clearing and toxic substances removing.For cough; Laryngopharynx swelling and pain; Scrofula; Goiter; Carbuncle; Furuncle; Venom; Traumatic injury; Arthromyodynia.
Herba Selaginellae Doederleinii: Zhang Zhongqian reports, by four types such as anticarcinogen composition compound treatment Senile Advanced primary lung cancer 34 examples such as Herba Selaginellae Doederleinii, point qi-deficiency type, YIN-deficiency type, type of deficiency of both QI and YIN and the hot stasis-toxin types of expectorant, dialectical plus-minus, treats 4 months, result: partial rcsponse 1 example, stablize 30 examples, worsen 3 examples; To survive 1 year 27 example, more than 1 year 6 example, more than 2 years 1 are routine; Dead 6 examples.Clinical treatment outcome illustrates also can obtain good therapeutic effect by treatment by Chinese herbs pulmonary carcinoma merely.
Folium cordylines fruticosae: heat clearing away, hemostasis, dissipating blood stasis.Control dysentery, spit blood, have blood in stool, stomachache, hematuria, menorrhagia, treating swelling and pain by traumatic injury.
Poria: sweet in the mouth, light, property are put down.Enter the heart, lung, spleen channel.There is the function of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach, dampness diuretic; Reduce phlegm, hidroschesis; Antiabortive; Increase appetite.The Rhizoma Atractylodis Macrocephalae contains volatile oil, atractylol, Rhizoma Atractylodis ketone and health is had to the vitamin A of benefiting action.
Radix Codonopsis: property is put down, sweet in the mouth, micro-acid.Return spleen, lung meridian.Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Fructus Lycii: the flat effect with the liver and the kidney tonifying of its sweet in the mouth, property, says in Compendium of Material Medica and " takes hard muscles and bones for a long time, make light of one's life by commiting suicide not old, resistance to cold and summer-heat." traditional Chinese medical science commonly use it treating hepatic and renal YIN deficiency, soreness of the waist and knees, dizziness, forgetful, dizzy, the many tear of blurred vision, quench one's thirst, the disease such as seminal emission.Modern pharmacology research confirms Fructus Lycii scalable body's immunity, can effectively grow and cell mutation, have the effect of slow down aging, anti-fatty liver, adjusting blood lipid and the aspect such as blood glucose, energy by Tumor suppression, and is applied to clinical.
Beneficial effect of the present invention: Poria, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Fructus Lycii four medicine merge, and have the effect of Fuzheng Zengxiao, can improve immunity of organisms, reduces toxic and side effects; Herba Scutellariae Barbatae, Herba Patriniae, Herba Solani Nigri, Fructus Forsythiae, Fructus Akebiae, Radix et Rhizoma Dysosmatis, Herba Selaginellae Doederleinii, Folium cordylines fruticosae heat-clearing and toxic substances removing and non-impairing the lung, can grow up by Tumor suppression, effectively kill tumor cell.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described; but not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various amendment or distortion that creative work can make still within protection scope of the present invention.
Embodiment 1:
A kind of Chinese medicine composition for the treatment of pulmonary carcinoma, be made up of the crude drug of following weight: Herba Scutellariae Barbatae 9 grams, Herba Patriniae 3 grams, Herba Solani Nigri 9 grams, Fructus Forsythiae 9 grams, Fructus Akebiae 3 grams, Radix et Rhizoma Dysosmatis 3 grams, Herba Selaginellae Doederleinii 3 grams, Folium cordylines fruticosae 3 grams, 9 grams, Poria, the Rhizoma Atractylodis Macrocephalae 5 grams, Radix Codonopsis 5 grams, Fructus Lycii 3 grams.
Above-mentioned medical material is put into marmite, and add the water soaking 2 hours of 4 times of doses, after water is boiled, with slow fire boiling 1 hour, filtering liquid medicine, can take.
Embodiment 2:
A kind of Chinese medicine composition for the treatment of pulmonary carcinoma, be made up of the crude drug of following weight: Herba Scutellariae Barbatae 20 grams, Herba Patriniae 10 grams, Herba Solani Nigri 20 grams, Fructus Forsythiae 20 grams, Fructus Akebiae 10 grams, Radix et Rhizoma Dysosmatis 10 grams, Herba Selaginellae Doederleinii 10 grams, Folium cordylines fruticosae 10 grams, 20 grams, Poria, the Rhizoma Atractylodis Macrocephalae 20 grams, Radix Codonopsis 20 grams, Fructus Lycii 20 grams.
Above-mentioned medical material is put into marmite, and add the water soaking 2 hours of 4 times of doses, after water is boiled, with slow fire boiling 1 hour, filtering liquid medicine, can take.
Embodiment 3:
A kind of Chinese medicine composition for the treatment of pulmonary carcinoma, be made up of the crude drug of following weight: Herba Scutellariae Barbatae 16 grams, Herba Patriniae 7 grams, Herba Solani Nigri 15 grams, Fructus Forsythiae 16 grams, Fructus Akebiae 8 grams, Radix et Rhizoma Dysosmatis 8 grams, Herba Selaginellae Doederleinii 7 grams, Folium cordylines fruticosae 5 grams, 18 grams, Poria, the Rhizoma Atractylodis Macrocephalae 15 grams, Radix Codonopsis 16 grams, Fructus Lycii 16 grams.
Above-mentioned medical material is put into marmite, and add the water soaking 2 hours of 4 times of doses, after water is boiled, with slow fire boiling 1 hour, filtering liquid medicine, can take.
Clinical data:
1, physical data
Be diagnosed as patients with advanced NSCLC through histopathology and cytolgical examination, the age is between 32-65; Important organ function of organization is normal.The patient meeting this research inclusion criteria is 100 examples.Man 55 example, female 45 example, 56.21 years old mean age.
2, Western medicine diagnose standard
Specified standard in " Chinese common cancer diagnosis and treatment specification " that Diagnosis of Non-Small Cell Lung standard adopts Department of Medical Administration of Ministry of Health of the People's Republic of China to write.
Tcm diagnosis standard
Formulating with reference to Ministry of Public Health " new Chinese medicine guideline of clinical investigations " (2002 editions), distinguishing as accumulateing disease in ecchymosis: cough, out of breath, chest pain, expectorant is yellow or expectorant blood is dark red, can with low grade fever, purplish tongue or have petechia, ecchymosis, yellow and thin fur, hesitant pulse or stringy and thready pulse.
3, Therapeutic Method
Be decocted in water for oral dose, every day, the potion embodiment of the present invention 3 Chinese medicine composition, point sooner or later took for twice, within 1 week, was a course for the treatment of.
4, criterion of therapeutical effect
Clinical disease criterion of therapeutical effect by cough, cough up phlegm, expectorant blood, uncomfortable in chest, chest pain, the common sympton such as out of breath, heating by light, in, be heavily divided into 3 grades (with reference to Ministry of Public Health " new Chinese medicine guideline of clinical investigations "), be designated as 2,4,6 points respectively, carry out accumulation contrast before the treatment afterwards, by integration than method Estimating curative effect.Effective: after treatment, symptom and sign integrated value declines >=2/3; Effective: after treatment, symptom and sign integrated value declines >=1/3, but ﹤ 2/3; Invalid: not reach effective standard person.
5, therapeutic effect
Clinical observation patients with lung cancer 100 example, treats after 4 courses for the treatment of through formula of the present invention, and disease improves effective 40 examples, effective 48 examples, effective percentage 88%.
Claims (3)
1. treat the Chinese medicine composition of pulmonary carcinoma for one kind, it is characterized in that it is made up of the crude drug of following weight proportioning: Herba Scutellariae Barbatae 9-20 gram, Herba Patriniae 3-10 gram, Herba Solani Nigri 9-20 gram, Fructus Forsythiae 9-20 gram, Fructus Akebiae 3-10 gram, Radix et Rhizoma Dysosmatis 3-10 gram, Herba Selaginellae Doederleinii 3-10 gram, Folium cordylines fruticosae 3-10 gram, Poria 9-20 gram, Rhizoma Atractylodis Macrocephalae 5-20 gram, Radix Codonopsis 5-20 gram, Fructus Lycii 3-20 gram.
2. a kind of Chinese medicine composition for the treatment of pulmonary carcinoma as claimed in claim 1, it is characterized in that it is made up of the crude drug of following weight proportioning: Herba Scutellariae Barbatae 10-18 gram, Herba Patriniae 4-8 gram, Herba Solani Nigri 11-17 gram, Fructus Forsythiae 10-18 gram, Fructus Akebiae 5-9 gram, Radix et Rhizoma Dysosmatis 5-10 gram, Herba Selaginellae Doederleinii 5-8 gram, Folium cordylines fruticosae 3-8 gram, Poria 12-20 gram, Rhizoma Atractylodis Macrocephalae 10-20 gram, Radix Codonopsis 10-18 gram, Fructus Lycii 5-18 gram.
3. a kind of Chinese medicine composition for the treatment of pulmonary carcinoma as claimed in claim 1, it is characterized in that it is made up of the crude drug of following weight proportioning: Herba Scutellariae Barbatae 16 grams, Herba Patriniae 7 grams, Herba Solani Nigri 15 grams, Fructus Forsythiae 16 grams, Fructus Akebiae 8 grams, Radix et Rhizoma Dysosmatis 8 grams, Herba Selaginellae Doederleinii 7 grams, Folium cordylines fruticosae 5 grams, 18 grams, Poria, the Rhizoma Atractylodis Macrocephalae 15 grams, Radix Codonopsis 16 grams, Fructus Lycii 16 grams.
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| CN105853618A (en) * | 2016-04-14 | 2016-08-17 | 黑龙江中医药大学 | Traditional Chinese medicine composition with broad-spectrum anti-cancer effect as well as preparation method and application thereof |
| CN106214707A (en) * | 2016-11-04 | 2016-12-14 | 谭淞文 | A kind of method of Folium cordylines fruticosae among the people treatment cancer |
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