CN103768541A - Medicine for treating chronic bronchitis - Google Patents

Medicine for treating chronic bronchitis Download PDF

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CN103768541A
CN103768541A CN201410065141.1A CN201410065141A CN103768541A CN 103768541 A CN103768541 A CN 103768541A CN 201410065141 A CN201410065141 A CN 201410065141A CN 103768541 A CN103768541 A CN 103768541A
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medicine
chronic bronchitis
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CN103768541B (en
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胡士万
尹燕东
侯庆喜
冯衍红
贾传斌
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PINGYIN COUNTY RENMIN HOSPITAL
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PINGYIN COUNTY RENMIN HOSPITAL
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Abstract

The invention discloses a medicine for treating chronic bronchitis. The medicine comprises the following bulk drugs: 10-15g of pinellia ternata, 10-15g of dried tangerine peel, 10-15g of poria, 6-9 g of liquorice, 6-10g of bulbus fritillariae cirrhosae, 10-20g of white mulberry root-bark, 10-15g of apricot kernel, 6-10g of fructus schizandrae, 10-20g of curcuma zedoary, 10-20g of Chinese angelica, 20-30g of fructus forsythiae, 20-30g of honeysuckle, 20-30g of isatis root, 20-30g of astragalus membranaceus, 10-15g of codonopsis pilosula, 10-15g of bighead atractylodes rhizome, 10-20g of divaricate saposhnikovia root, 10-20g of paniculate swallowwort root, 10-20g of schizonepeta, 10-20g of cicada slough, and 6-10g of platycodon grandiflorum. The medicine has the beneficial effect of high cure rate, relapse prevention, immunity regulation and no drug tolerance, and is a novel medicine for treating chronic bronchitis at present.

Description

A kind of medicine for the treatment of chronic bronchitis
Technical field
The present invention relates to a kind of Chinese medicine compound, particularly relate to a kind of medicine for the treatment of chronic bronchitis.
Background technology
" chronic bronchitis " is modern doctor trained in Western medicine name of disease, is called for short " chronic bronchitis ", refers to the chronic non-specific inflammation of trachea, bronchus and surrounding tissue thereof.Clinically take cough, expectoration or with pant and the chronic process of outbreak repeatedly as feature, Relapse rate outbreak, slow progress, Chang Bingfa obstructive emphysema, even pulmonary hypertension, pulmonary heart disease.It is clinical the most common, chronic respiratory system diseases that serious harm people are healthy, and especially middle-aged and elderly people is common.Cause great pain, caused huge financial burden to patient and his family to patient.Along with scientific and technical develop rapidly, western medical treatment acute respiratory infection effect still can, but treatment chronic bronchitis way is few.We were through the continuous exploration of more than 30 years, dialectical treatment primary disease has accumulated abundant treatment experience, the present invention treats chronic bronchitis and has instant effect, cure rate is high, be difficult for the advantage of recurrence, and do not produce drug resistance, save antibiotic, significant to current clinical antibiotics abuse phenomenon and bacterial resistance.
Summary of the invention
The technical problem that the present invention solves is: a kind of medicine for the treatment of chronic bronchitis is provided.Not only instant effect of this Drug therapy chronic bronchitis, cure rate is high, is difficult for recurrence, but also does not produce drug resistance, saves antibiotic.
Technical scheme of the present invention is: a kind of medicine for the treatment of chronic bronchitis, it is characterized in that, its crude drug consists of: Rhizoma Pinelliae 10-15 gram, Pericarpium Citri Reticulatae 10-15 gram, Poria 10-15 gram, Radix Glycyrrhizae 6-9 gram, Bulbus Fritillariae Cirrhosae 6-10 gram, Cortex Mori 10-20 gram, Semen Armeniacae Amarum 10-15 gram, Fructus Schisandrae Chinensis 6-10 gram, Rhizoma Curcumae 10-20 gram, Radix Angelicae Sinensis 10-20 gram, Fructus Forsythiae 20-30 gram, Flos Lonicerae 20-30 gram, Radix Isatidis 20-30 gram, Radix Astragali 20-30 gram, Radix Codonopsis 10-15 gram, Rhizoma Atractylodis Macrocephalae 10-15 gram, Radix Saposhnikoviae 10-20 gram, Radix Cynanchi Paniculati 10-20 gram, Herba Schizonepetae 10-20 gram, Periostracum Cicadae 10-20 gram, Radix Platycodonis 6-10 gram.
The preferred technical scheme of the present invention is: a kind of medicine for the treatment of chronic bronchitis, it is characterized in that, and its crude drug consists of: 15 grams of the Rhizoma Pinelliaes, 15 grams of Pericarpium Citri Reticulataes, 15 grams, Poria, 6 grams, Radix Glycyrrhizae, 6 grams of Bulbus Fritillariae Cirrhosaes, 20 grams of Cortex Mori, 15 grams, Semen Armeniacae Amarum, 6 grams of Fructus Schisandrae Chinensis, 10 grams of Rhizoma Curcumae, 10 grams of Radix Angelicae Sinensis, 30 grams of Fructus Forsythiaes, 20 grams of Flos Loniceraes, 30 grams of Radix Isatidis, 30 grams of the Radixs Astragali, 15 grams of Radix Codonopsis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Radix Saposhnikoviaes, 10 grams of Radix Cynanchi Paniculatis, 20 grams of Herba Schizonepetae, 20 grams of Periostracum Cicadaes, 10 grams of Radix Platycodoniss.
The further preferred technical scheme of the present invention is: a kind of medicine for the treatment of chronic bronchitis, it is characterized in that, and its crude drug composition also comprises: 10 grams of Pheretimas, 10 grams of Radix Scutellariaes, 10 grams of Fructus Gardeniaes.
Described a kind of medicine for the treatment of chronic bronchitis, is characterized in that: described medicine can be made decoction, powder, pill, unguentum, syrup, tablet, granule or powder preparation to be taken after being infused in boiling water, granule, capsule.
Described pill can be honeyed pill, the watered pill, paste pill or concentrated pill, and described unguentum can be fluid extract, extractum or soft extract.
The decoction of described decoction is: decoct first with 800-1000 milliliters, cold water, soak 30 points to 60 minutes, 30 minutes at a simmer, leach medicine juice; Two decoct and add cold water or boiled water 500-800 milliliter, and slow fire is decocted 20-25 minute again, leaches medicine juice for twice and mixes even.
Instructions of taking: will decoct the Chinese herbs decoction mixing, sooner or later point 2 warm taking orally.The potion on the one of adding medicine to, ten days courses for the treatment of, takes 2 courses for the treatment of.Add and subtract with card according to the state of an illness.Period in a medicine diet is excessively sweet, over-salty, greasy, raw food and maror, notes warmingly, avoid suffering from cold, and restraining sexual life.
One, the effect of each material medicine and mechanism
The present invention is by adopting the forward position means of modern scientific research, study with reference to herbal pharmacology with differential diagnosis in tcm theory, both strictly deferred to the dialectical system of principle-method-recipe-medicines of the traditional Chinese medical science, emphasize again take the etiology and pathology of doctor trained in Western medicine as basis, in conjunction with Chinese medicine active chemical, according to herbal pharmacology, drug effect and pharmacokinetics basis further investigated Chinese traditional treatment rule.Inventor thinks: chronic bronchitis morbidity, and with spleen insufficiency, the main pathomechanism of phlegm dampness in lungs, the sick position of primary disease, at lung, relates to spleen.And chronic bronchitis is the chronic non-specific inflammation of trachea, bronchus and surrounding tissue thereof, with the passing of time, respiratory mucosa and column Ciliated epithelium are impaired, tie hoof hamartoplasia under mucosa for the course of disease, and disturbance of blood circulation, has further increased the weight of this pathology process.Therefore the present invention has established air making-up and spleen enlivening, and preventing phlegm from forming and stopping coughing is primary treatment method, takes into account other pathological factors.The Chinese medicine that the present invention selects can air making-up and spleen enlivening, preventing phlegm from forming and stopping coughing; Sterilizing and anti-virus; Blood circulation promoting and blood stasis dispelling, improves respiratory tract blood circulation; Health invigorating, regulates immunity, and prevention is suffered from cold and repeated flu.
The Rhizoma Pinelliae: nature and flavor are pungent, warm, poisonous, attach to the lung and stomach meridians.Effect: antitussive, eliminate the phlegm.
Pericarpium Citri Reticulatae: nature and flavor acrid, bitter, warm.Return spleen lung meridian.Effect: antiinflammatory, relaxing smooth muscle.
Poria: property slightly sweet flavor is flat.GUIXIN, spleen, lung meridian.Effect: the ethanol extraction of Poria has bactericidal action, can kill leptospira.
Radix Glycyrrhizae: nature and flavor are sweet, returns spleen, stomach, lung meridian.Effect: antiinflammatory and anti-allergy action, there is the effect of glucocorticoid sample, antitussive effect simultaneously, promote the recovery of respiratory inflammation, the alleviation of symptom.
Bulbus Fritillariae Cirrhosae: nature and flavor hardship, sweet, cool, return lung meridian.Effect: there is relaxing smooth muscle effect.
Cortex Mori: nature and flavor are sweet, cold, return lung, spleen channel.Effect: eliminating pathogen from the lung for relieving asthma, line water detumescence.
Semen Armeniacae Amarum: nature and flavor hardship, temperature, poisonous, return lung, large intestine channel.Effect: expelling phlegm for arresting cough, relieving asthma, intestine moistening.
Fructus Schisandrae Chinensis: nature and flavor acid, temperature, return lung, kidney channel.Effect: astringe the lung, nourishing kidney, promotes the production of body fluid, receives antiperspirant, arresting seminal emission.
Radix Angelicae Sinensis: nature and flavor are sweet, pungent, warm, GUIXIN, liver, spleen channel.Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturizes laxation.
Pheretima: nature and flavor are salty, cold, return liver, spleen, lung meridian.Effect: heat clearing away, suppressing the hyperactive liver, Zhichuan, dredging collateral.
Flos Lonicerae; Nature and flavor are sweet, cold, attach to the lung and stomach meridians.Effect: heat-clearing and toxic substances removing.Cure mainly: epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, dripping, anal fistula.
Fructus Forsythiae: nature and flavor hardship, cool, GUIXIN, liver, gallbladder meridian.Effect: heat-clearing and toxic substances removing, mass dissipating and swelling eliminating.
Radix Isatidis: nature and flavor hardship, cold, return liver, stomach warp.Effect: heat clearing away, removing toxic substances, removing heat from blood
The Radix Astragali: nature and flavor are sweet, tepor, return lung, spleen channel.Effect: invigorating QI to consolidate the body surface resistance, inducing diuresis to remove edema, poison holding, granulation promoting.
Radix Codonopsis: nature and flavor are sweet, flat, return lung, spleen channel.Effect: invigorating middle warmer, QI invigorating, promotes the production of body fluid.
The Rhizoma Atractylodis Macrocephalae: nature and flavor hardship, sweet, warm, return spleen, stomach warp.Effect: spleen reinforcing, stomach reinforcing, dampness, and in.
Radix Saposhnikoviae: nature and flavor acrid, sweet, warm, return bladder, lung, spleen channel.Effect: deliver, dispel the wind, victory is wet, pain relieving.
Radix Cynanchi Paniculati: nature and flavor are pungent, warm, return bladder, spleen channel.Effect: analgesia, cough-relieving, inducing diuresis to remove edema, promoting blood circulation and detoxication.
Herba Schizonepetae: nature and flavor are pungent, warm, return lung, Liver Channel.Effect: deliver, dispel the wind, treating blood disorders.
Periostracum Cicadae: property sweet-salty, cool, return lung, Liver Channel.Effect: loose wind heat, lung qi dispersing, determines convulsion.
Radix Platycodonis: nature and flavor toil, flat, return lung, stomach warp.Effect: open lung qi dispersing gas, the evacuation of pus of eliminating the phlegm.Effect.
As mentioned above, the main pathomechanism of chronic bronchitis is spleen insufficiency, phlegm dampness in lungs, and the selected above-mentioned Radix Codonopsis of the present invention, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Glycyrrhizae four taste Chinese medicines are decoction of four noble drugs, Radix Codonopsis invigorating the spleen and benefiting QI in decoction of four noble drugs, is principal agent; The Rhizoma Atractylodis Macrocephalae can be strengthened the function of invigorating spleen of Radix Codonopsis, and the energy dampness of holding concurrently, is accessory drugs; Poria dampness removing, raw wet to remove spleen insufficiency, can assist Rhizoma Atractylodis Macrocephalae spleen invigorating simultaneously, be adjuvant drug; Radix Glycyrrhizae can help Radix Codonopsis invigorating the spleen and replenishing QI, simultaneously can nourishing the lung to arrest cough, and coordinating the actions of various ingredients in a prescription, for making medicine.Decoction of four noble drugs adds Pericarpium Citri Reticulatae, the Rhizoma Pinelliae is Liujunzi Tang, Pericarpium Citri Reticulatae activating QI to eliminate phlegm, the spleen strengthening and damp drying; Rhizoma Pinelliae drying dampness to eliminate phlegm.The spleen being the source of producing phlegm, lung is the device of storage expectorant.Six medicines share, function air making-up and spleen enlivening, and building up the spleen to supplement the lung, to remove the source of producing phlegm; Simultaneously can resolving phlegm and drying damp, with the expectorant of dispelling in lung.Liujunzi Tang is the primary treatment part during the present invention writes out a prescription, the principal agent of writing out a prescription for composition the present invention altogether.In side, Cortex Mori, Bulbus Fritillariae Cirrhosae, Semen Armeniacae Amarum, Pheretima assist principal agent to reduce phlegm, the energy relieving cough and asthma of holding concurrently; The Radix Astragali is assisted principal agent QI invigorating tonifying the lung, and with the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae compatibility, composition prescription YUPINGFENG SAN, can invigorating QI to consolidate the body surface resistance, and have and strengthen the ability of resisting exopathogen invasion and attack, be accessory drugs altogether.Fructus Forsythiae, Flos Lonicerae, Radix Isatidis lung-heat clearing and detoxification, can ferment heat-transformation by prophylactic treatment phlegm-damp, and exopathogen closes lung heat-transformation, wind-heat invading the lung; Radix Angelicae Sinensis, Pheretima blood circulation promoting and blood stasis dispelling, the prophylactic treatment cough illness lung network of a specified duration of using becomes silted up and hinders; Herba Schizonepetae, Radix Saposhnikoviae, Periostracum Cicadae, Radix Cynanchi Paniculati expelling pathogenic wind from the body surface, with the passing of time the treatment cough with asthma of using, feels ailment said due to cold or exposure again; Fructus Schisandrae Chinensis astringing lung-QI and relieving cough; Be adjuvant drug altogether.Radix Platycodonis is introduced lung, and assists principal agent lung qi dispersing to eliminate the phlegm, and is for making medicine.
All medicines share, can air making-up and spleen enlivenings, and preventing phlegm from forming and stopping coughing; Lung qi dispersing dispels the wind; Lung-heat clearing and detoxification; Blood circulation promoting and blood stasis dispelling, dredging lung network; Invigorating QI to consolidate the body surface resistance, prevention is suffered from cold and is repeated flu.Thereby treating both the principal and secondary aspects of a disease, deficiency and excess is also adjusted, treatment primary disease, temper is good for fortune, and phlegm-damp loses source; Tu Wang gold is hard, and lung qi a surname falls again normal, cough with asthma spontaneous recovery; Table Gu Wei fills, and in healthy energy is deposited, heresy can not be done, and primary disease is difficult for recurrence.
Two, the medicine modern pharmacology pharmacodynamic action of above-mentioned treatment chronic bronchitis shows in the following areas:
Relieving cough and expelling phlegm: the present invention selects the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Poria, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae, Cortex Mori, Semen Armeniacae Amarum, Radix Platycodonis, Fructus Schisandrae Chinensis, all medicines of Pheretima, has respectively excited respiratory center, alleviates respiratory tract smooth muscle spasm, promotes respiratory mucosa secretion, antitussive, the effect such as eliminate the phlegm.
Anti-bacteria and anti-virus: the present invention selects the heat-clearing and toxic substances removing medicines such as Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, there is significantly antibacterial, antivirus action, respectively various bacteria, virus and leptospira are had to obvious killing action, thereby there is obvious antiinflammatory action.
Improve respiratory tract blood circulation: Radix Angelicae Sinensis in the present invention, Pheretima can blood circulation promoting and blood stasis dispelling, improve respiratory tract blood circulation, thereby promote the reparation of respiratory tract injury tissue.
Enhancing immunity: show according to pharmacological research and a large amount of clinical practices, Radix Codonopsis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae in the present invention, Radix Saposhnikoviae can health invigorating, strengthening superficial resistance to stop perspiration, preventing cold, thus avoid the repeated infection of respiratory tract, reduce damage frequency and the degree of injury of respiratory tract.
Anti-allergic effects: observe the Chronic Cough Patients of significant proportion, the symptom that has itching throat to cough according to a large amount of clinical practices; According to pathological study, there is sensitized cell in chronic bronchitis patient respiratory mucosa.According to pharmacological research, in the present invention, Herba Schizonepetae, Radix Saposhnikoviae, Periostracum Cicadae, Radix Cynanchi Paniculati have respectively anti-allergic effects in various degree, can eliminate respiratory tract congestion and edema, promote inflammation to recover, and accelerate the improvement of symptom and sign.
Three, observation of curative effect method of the present invention
In research process of the present invention, all select traditional Chinese medical science clinic outpatients, all chronic bronchitis and acute episode of chronic bronchitis patient all meet the diagnostic criteria of in November, 1979 whole nation chronic bronchitis clinical speciality meeting revision, screen altogether 195 patients, wherein male patient 117 people, female patient 78 people, the age between 10~72 years old, mean age (46.7 ± 5.3) year; The course of disease between 1~31 year, average course of disease 12.7.Be divided at random treatment group and matched group, wherein treatment group 130 people, matched group 65 people in the ratio of 1.5:1 by medical priority.Two groups of chronic bronchitis people, at basic document contrast there was no significant differences such as the weights of sex, age, the course of disease, the state of an illness, have comparability (P > 0.05).
Therapeutic Method: treatment group Therapeutic Method is as above-mentioned; The control group Juhong Wan, each two balls, every day three times, LIFEI PIAN, each two, every day twice, acute attack person is according to feelings fit applications antibiotic.Two groups of patients treat two weeks continuously, observe the curative effect.
Criterion of therapeutical effect: all chronic bronchitis and acute episode of chronic bronchitis patient's criterion of therapeutical effect is all according to the standard of in November, 1979 whole nation chronic bronchitis clinical speciality meeting revision.
Its result is as follows.
Table 1 liang group patient summary sheet
Figure BDA0000469462700000081
Table 2 liang group patient treatment effect comparison
Figure BDA0000469462700000082
The situation of change of immunologic function before and after table 3 liang group patient treatment
Figure BDA0000469462700000083
Before and after two groups of patient treatments, immune function contrast has significant difference P ﹤ 0.05
Can find out from the data of above table, adopt Chinese medicine provided by the invention, in treatment chronic bronchitis and acute episode of chronic bronchitis, aspect clinic control rate and total effective rate (50.77%; 92.31%) be all better than matched group (33.85%; 84.62%); Treatment group and matched group contrast and also have significant difference aspect immunologic function before and after treatment in addition.
Four, medical record for example;
1, patient king so-and-so, man, 51 years old, because of recurrent cough 11 years, the postemphasis of suffering from cold before month remaining, successively apply quiet of penicillin, amikacin, cefazolin, ambroxol in conjunction with oral FUFANG GANCAO PIAN, aminophylline, intensified loquet distillate etc. at local hospital, more than treatment month, curative effect is not obvious and examine.Patient's itching throat cough when medical, uttering phlegm amount is many, accompanies asthma uncomfortable in chest.Have a medical check-up: patient chest is tubbiness, two lungs are heard and dry moist rale; Rabat shows the broadening of bilateral intercostal space, two increased bronchovascular shadows disorders; Light red tongue, greasy after tongue is white, rolling pulse.Routine blood test: leukocyte 8600, neutrophilic leukocyte 72%.Immunologic function: LgA0.66g/L; LgG6.4g/L; LgM0.51g/L.Prescription: 15 grams of the Rhizoma Pinelliaes, 15 grams of Pericarpium Citri Reticulataes, 15 grams, Poria, 6 grams, Radix Glycyrrhizae, 6 grams of Bulbus Fritillariae Cirrhosaes, 20 grams of Cortex Mori, 15 grams, Semen Armeniacae Amarum, 6 grams of Fructus Schisandrae Chinensis, 10 grams of Rhizoma Curcumae, 10 grams of Radix Angelicae Sinensis, 30 grams of Fructus Forsythiaes, 20 grams of Flos Loniceraes, 30 grams of Radix Isatidis, 30 grams of the Radixs Astragali, 15 grams of Radix Codonopsis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Radix Saposhnikoviaes, 10 grams of Radix Cynanchi Paniculatis, 20 grams of Herba Schizonepetae, 20 grams of Periostracum Cicadaes, 10 grams of Radix Platycodoniss.Decoct first with 900 milliliters, cold water, soak 30 minutes, 30 minutes at a simmer, leach medicine juice; Two decoct and add 600 milliliters of slow fire of boiled water to decoct 25 minutes again, leach for twice medicine juice mix even, sooner or later points 2 times warm for oral administration, potion on the one.Take medicine 14, itching throat cough is spat, asthma uncomfortable in chest, and the dry moist rale of two lungs disappears; Check routine blood test: leukocyte 6500, neutrophilic leukocyte 53%.Immunologic function: LgA1.01g/L:LgG12.03g/L:LgM1.11g/L; Follow up a case by regular visits to three months without recurrence.
2, patient Zhang, man, 59 years old, because of recurrent cough 15 years, the postemphasis of suffering from cold before first quarter moon, treated more than ten days in conjunction with oral antisussive and expectorant agent quiet of local hospital application penicillin, and curative effect is not obvious and examine.When medical, patient's itching throat is coughed, and in uttering phlegm amount, accompanies asthma uncomfortable in chest.Have a medical check-up: patient chest is tubbiness, two lungs are heard and rale sound; Rabat shows the broadening of bilateral intercostal space, two increased bronchovascular shadows disorders; Light red tongue, white and greasy fur, rolling pulse.Routine blood test: leukocyte 9700, neutrophilic leukocyte 79%.Immunologic function: LgA0.71g/L; LgG6.9g/L; LgM0.53g/L.Prescription: 10 grams of the Rhizoma Pinelliaes, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Poria, 6 grams, Radix Glycyrrhizae, 6 grams of Bulbus Fritillariae Cirrhosaes, 10 grams of Cortex Mori, 10 grams, Semen Armeniacae Amarum, 6 grams of Fructus Schisandrae Chinensis, 10 grams of Pheretimas, 10 grams of Radix Angelicae Sinensis, 15 grams of Fructus Forsythiaes, 15 grams of Flos Loniceraes, 15 grams of Radix Isatidis, 20 grams of the Radixs Astragali, 10 grams of Radix Codonopsis, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Radix Saposhnikoviaes, 10 grams of Radix Cynanchi Paniculatis, 20 grams of Herba Schizonepetae, 10 grams of Periostracum Cicadaes, 10 grams of Radix Platycodoniss.Decoct first with 900 milliliters, cold water, soak 30 minutes, 30 minutes at a simmer, leach medicine juice; Two decoct and add 600 milliliters of slow fire of boiled water to decoct 25 minutes again, leach for twice medicine juice mix even, sooner or later points 2 times warm for oral administration, potion on the one.Take medicine 14, itching throat cough is spat, asthma uncomfortable in chest, and two lung rale sounds disappear; Check routine blood test: leukocyte 7100, neutrophilic leukocyte 55%.Immunologic function: LgA1.02g/L:LgG11.10g/L:LgM1.21g/L; Follow up a case by regular visits to three months without recurrence.
3, grandson patient so-and-so, female, 45 years old, because of recurrent cough 7 years, the postemphasis of suffering from cold before 20 days,, treated more than ten days in conjunction with oral antisussive and expectorant agent at quiet cefoperazone sodium of local hospital, curative effect is not obvious and examine.When medical, patient's cough, tells in yellow sputum amount, pharyngeal gargalesthesia sometimes, and itching throat is coughed, companion's chest distress.Have a medical check-up: patient chest is tubbiness, two lungs are heard and wheezing sound; Red tongue, yellowish fur, stringy and rolling pulse; Rabat shows the broadening of bilateral intercostal space, two increased bronchovascular shadows disorders.Routine blood test: leukocyte 12600, neutrophilic leukocyte 81%.Immunologic function: LgA0.69g/L; LgG6.7g/L; LgM0.55g/L.Prescription: 10 grams of the Rhizoma Pinelliaes, 10 grams of Pericarpium Citri Reticulataes, Poria 10-gram, 6 grams, Radix Glycyrrhizae, 10 grams of Radix Codonopsis, 6 grams of Bulbus Fritillariae Cirrhosaes, 20 grams of Cortex Mori, 10 grams, Semen Armeniacae Amarum, 10 grams of Radix Angelicae Sinensis, 30 grams of Fructus Forsythiaes, 30 grams of Flos Loniceraes, 30 grams of Radix Isatidis, 10 grams of the Radixs Astragali, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Radix Saposhnikoviaes, 10 grams of Herba Schizonepetae, 10 grams of Radix Platycodoniss, 10 grams of Radix Cynanchi Paniculatis, 10 grams of Periostracum Cicadaes, 10 grams of Radix Scutellariaes, 10 grams of Fructus Gardeniaes, 10 grams of Pheretimas.Decoct first with 900 milliliters, cold water, soak 30 minutes, 30 minutes at a simmer, leach medicine juice; Two decoct and add 600 milliliters of slow fire of boiled water to decoct 25 minutes again, leach for twice medicine juice mix even, sooner or later points 2 times warm for oral administration, potion on the one.Take medicine 14, yellow sputum is told in cough, and chest distress and two lung wheezing sound disappear; Check routine blood test: leukocyte 6900, neutrophilic leukocyte 69%.Immunologic function: LgA0.99g/L:LgG10.02g/L:LgM1.13g/L; Follow up a case by regular visits to three months without recurrence.
Beneficial effect of the present invention is: pharmacology of the present invention is that treatment chronic bronchitis and acute episode of chronic bronchitis have instant effect, and cure rate is high, is difficult for recurrence; The present invention can preventing phlegm from forming and stopping coughing; Sterilizing and anti-virus; Blood circulation promoting and blood stasis dispelling, improves respiratory tract blood circulation; Health invigorating, regulates immunity, and prevention is suffered from cold and repeated flu; Do not produce drug resistance, save antibiotic, significant to current clinical antibiotics abuse phenomenon and bacterial resistance.A kind of newtype drug for the treatment of chronic bronchitis and acute episode of chronic bronchitis at present.
The specific embodiment
The specific embodiment of the invention is:
Embodiment 1,
A, take 15 grams of the Rhizoma Pinelliaes, 15 grams of Pericarpium Citri Reticulataes, 15 grams, Poria, 6 grams, Radix Glycyrrhizae, 6 grams of Bulbus Fritillariae Cirrhosaes, 20 grams of Cortex Mori, 15 grams, Semen Armeniacae Amarum, 6 grams of Fructus Schisandrae Chinensis, 10 grams of Rhizoma Curcumae, 10 grams of Radix Angelicae Sinensis, 30 grams of Fructus Forsythiaes, 20 grams of Flos Loniceraes, 30 grams of Radix Isatidis, 30 grams of the Radixs Astragali, 15 grams of Radix Codonopsis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Radix Saposhnikoviaes, 10 grams of Radix Cynanchi Paniculatis, 20 grams of Herba Schizonepetae, 20 grams of Periostracum Cicadaes, 10 grams of Radix Platycodoniss are for subsequent use;
B, decoct with 900 milliliters of herbal medicine immersions that steps A has been prepared of cold water 30 minutes first, 30 minutes at a simmer, leach medicine juice; Two decoct and add 600 milliliters, boiled water, and slow fire is decocted 25 minutes again, leach for twice medicine juice mix even, sooner or later points 2 times warm for oral administration, potion on the one.
Embodiment 2
A, take 10 grams of the Rhizoma Pinelliaes, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Poria, 6 grams, Radix Glycyrrhizae, 6 grams of Bulbus Fritillariae Cirrhosaes, 10 grams of Cortex Mori, 10 grams, Semen Armeniacae Amarum, 6 grams of Fructus Schisandrae Chinensis, 10 grams of Pheretimas, 10 grams of Radix Angelicae Sinensis, 15 grams of Fructus Forsythiaes, 15 grams of Flos Loniceraes, 15 grams of Radix Isatidis, 20 grams of the Radixs Astragali, 10 grams of Radix Codonopsis, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Radix Saposhnikoviaes, 10 grams of Radix Cynanchi Paniculatis, 20 grams of Herba Schizonepetae, 10 grams of Periostracum Cicadaes, 10 grams of Radix Platycodoniss are for subsequent use;
B, decoct with 900 milliliters of herbal medicine immersions that steps A has been prepared of cold water 30 minutes first, 30 minutes at a simmer, leach medicine juice; Two decoct and add 600 milliliters of slow fire of boiled water to decoct 25 minutes again, leach for twice medicine juice mix even, sooner or later points 2 times warm for oral administration, potion on the one.
Embodiment 3
A, take 10 grams of the Rhizoma Pinelliaes, 10 grams of Pericarpium Citri Reticulataes, 10 grams, Poria, 6 grams, Radix Glycyrrhizae, 10 grams of Radix Codonopsis, 6 grams of Bulbus Fritillariae Cirrhosaes, 20 grams of Cortex Mori, 10 grams, Semen Armeniacae Amarum, 10 grams of Radix Angelicae Sinensis, 30 grams of Fructus Forsythiaes, 30 grams of Flos Loniceraes, 30 grams of Radix Isatidis, 10 grams of the Radixs Astragali, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Radix Saposhnikoviaes, 10 grams of Herba Schizonepetae, 10 grams of Radix Platycodoniss, 10 grams of Radix Cynanchi Paniculatis, 10 grams of Periostracum Cicadaes, 10 grams of Radix Scutellariaes, 10 grams of Fructus Gardeniaes, 10 grams of Pheretimas are for subsequent use;
B, decoct with 900 milliliters of herbal medicine immersions that steps A has been prepared of cold water 30 minutes first, 30 minutes at a simmer, leach medicine juice; Two decoct and add 600 milliliters of slow fire of boiled water to decoct 25 minutes again, leach for twice medicine juice mix even, sooner or later points 2 times warm for oral administration, potion on the one.

Claims (6)

1. a medicine for the treatment of chronic bronchitis, is characterized in that, its crude drug consists of: Rhizoma Pinelliae 10-15 gram, Pericarpium Citri Reticulatae 10-15 gram, Poria 10-15 gram, Radix Glycyrrhizae 6-9 gram, Bulbus Fritillariae Cirrhosae 6-10 gram, Cortex Mori 10-20 gram, Semen Armeniacae Amarum 10-15 gram, Fructus Schisandrae Chinensis 6-10 gram, Rhizoma Curcumae 10-20 gram, Radix Angelicae Sinensis 10-20 gram, Fructus Forsythiae 20-30 gram, Flos Lonicerae 20-30 gram, Radix Isatidis 20-30 gram, Radix Astragali 20-30 gram, Radix Codonopsis 10-15 gram, Rhizoma Atractylodis Macrocephalae 10.-15 gram, Radix Saposhnikoviae 10-20 gram, Radix Cynanchi Paniculati 10-20 gram, Herba Schizonepetae 10-20 gram, Periostracum Cicadae 10-20 gram, Radix Platycodonis 6-10 gram.
2. a kind of medicine for the treatment of chronic bronchitis according to claim 1, is characterized in that, its crude drug consists of: 15 grams of the Rhizoma Pinelliaes, 15 grams of Pericarpium Citri Reticulataes, 15 grams, Poria, 6 grams, Radix Glycyrrhizae, 6 grams of Bulbus Fritillariae Cirrhosaes, 20 grams of Cortex Mori, 15 grams, Semen Armeniacae Amarum, 6 grams of Fructus Schisandrae Chinensis, 10 grams of Rhizoma Curcumae, 10 grams of Radix Angelicae Sinensis, 30 grams of Fructus Forsythiaes, 20 grams of Flos Loniceraes, 30 grams of Radix Isatidis, 30 grams of the Radixs Astragali, 15 grams of Radix Codonopsis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 20 grams of Radix Saposhnikoviaes, 10 grams of Radix Cynanchi Paniculatis, 20 grams of Herba Schizonepetae, 20 grams of Periostracum Cicadaes, 10 grams of Radix Platycodoniss.
3. a kind of medicine for the treatment of chronic bronchitis according to claim 2, is characterized in that, its crude drug composition also comprises: 10 grams of Pheretimas, 10 grams of Radix Scutellariaes, 10 grams of Fructus Gardeniaes.
4. according to a kind of medicine for the treatment of chronic bronchitis described in claims 1 to 3 any one, it is characterized in that: described Chinese medicine can be made decoction, powder, pill, unguentum, syrup, tablet, granule or powder preparation to be taken after being infused in boiling water, granule, capsule.
5. a kind of medicine for the treatment of chronic bronchitis according to claim 4, is characterized in that: described pill can be honeyed pill, the watered pill, paste pill or concentrated pill, described unguentum can be fluid extract, extractum or soft extract.
6. the preparation method of a kind of medicine for the treatment of chronic bronchitis claimed in claim 4, is characterized in that: the decoction method of described decoction is: take respectively in grams each crude drug by crude drug composition for subsequent use; Decoct first with 800-1000 milliliters, cold water the above-mentioned whole crude drug that prepare are soaked to 30 points to 60 minutes, 30 minutes at a simmer, leach medicine juice; Two decoct and add cold water or boiled water 500-800 milliliter slow fire to decoct 20-25 minute again, leach medicine juice for twice and mix even.
CN201410065141.1A 2014-02-25 2014-02-25 A kind of medicine for the treatment of chronic bronchitis Expired - Fee Related CN103768541B (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104383508A (en) * 2014-12-07 2015-03-04 唐云峰 Traditional Chinese medicine composition for treating chronic bronchitis
CN104524280A (en) * 2014-12-19 2015-04-22 孙晓兵 Traditional Chinese medicine capsule for treating chronic bronchitis and preparation method of traditional Chinese medicine capsule
CN104623482A (en) * 2015-02-09 2015-05-20 王健秀 Traditional Chinese medicine preparation for treating bronchial asthma
CN104800584A (en) * 2015-05-14 2015-07-29 奉化科创科技服务有限公司 Traditional Chinese medicine for treating cough
CN104826031A (en) * 2015-05-30 2015-08-12 青岛辰达生物科技有限公司 Traditional Chinese medicine composition for treating chronic bronchitis and usage thereof
CN104958608A (en) * 2015-07-25 2015-10-07 徐显廷 Traditional Chinese medicine oral liquid for treating infantile cough
CN105055825A (en) * 2015-08-05 2015-11-18 李强 Pharmaceutical preparation for treating bronchitis
CN105079355A (en) * 2015-09-23 2015-11-25 谢桂斌 Medicine for treating senile emphysema
CN105853720A (en) * 2016-04-29 2016-08-17 胡连华 Medicine for radically curing chronic bronchitis and preparation method
CN106138668A (en) * 2016-08-18 2016-11-23 陈定潜 A kind of Chinese medicine composition treating COPD and preparation method thereof

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104383508A (en) * 2014-12-07 2015-03-04 唐云峰 Traditional Chinese medicine composition for treating chronic bronchitis
CN104524280A (en) * 2014-12-19 2015-04-22 孙晓兵 Traditional Chinese medicine capsule for treating chronic bronchitis and preparation method of traditional Chinese medicine capsule
CN104623482A (en) * 2015-02-09 2015-05-20 王健秀 Traditional Chinese medicine preparation for treating bronchial asthma
CN104800584A (en) * 2015-05-14 2015-07-29 奉化科创科技服务有限公司 Traditional Chinese medicine for treating cough
CN104826031A (en) * 2015-05-30 2015-08-12 青岛辰达生物科技有限公司 Traditional Chinese medicine composition for treating chronic bronchitis and usage thereof
CN104958608A (en) * 2015-07-25 2015-10-07 徐显廷 Traditional Chinese medicine oral liquid for treating infantile cough
CN105055825A (en) * 2015-08-05 2015-11-18 李强 Pharmaceutical preparation for treating bronchitis
CN105079355A (en) * 2015-09-23 2015-11-25 谢桂斌 Medicine for treating senile emphysema
CN105853720A (en) * 2016-04-29 2016-08-17 胡连华 Medicine for radically curing chronic bronchitis and preparation method
CN106138668A (en) * 2016-08-18 2016-11-23 陈定潜 A kind of Chinese medicine composition treating COPD and preparation method thereof
CN106138668B (en) * 2016-08-18 2019-09-10 陈定潜 A kind of Chinese medicine composition and preparation method thereof for treating Chronic Obstructive Pulmonary Disease

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