CN106417333B

CN106417333B - Seed treatment dispersible powder containing dimethomorph and propamocarb and application thereof

Info

Publication number: CN106417333B
Application number: CN201610845852.XA
Authority: CN
Inventors: 孙国庆; 侯永生; 吴勇; 张全; 赵保臣; 张小兵
Original assignee: Shandong Runbo Biological Technology Co Ltd
Current assignee: Shandong Runbo Biological Technology Co Ltd
Priority date: 2016-09-23
Filing date: 2016-09-23
Publication date: 2021-07-02
Anticipated expiration: 2036-09-23
Also published as: CN106417333A

Abstract

The invention discloses a seed treatment dispersible powder containing dimethomorph and propamocarb and application thereof, wherein the seed treatment dispersible powder comprises the following components in percentage by weight: 10-80% of active pharmaceutical ingredients, 4-10% of dispersing agents, 1-5% of wetting agents, 1-10% of film forming agents, 1-10% of anti-caking agents, 0.1-5% of coloring agents and the balance of fillers; the active ingredients of the medicine are dimethomorph and propamocarb. The dimethomorph and the propamocarb are compounded to prepare the seed treatment dispersible powder, and the dimethomorph and the propamocarb belong to two bactericides with different action mechanisms, and the dimethomorph and the propamocarb are mutually mixed without conflict, so that the dimethomorph and the propamocarb have good synergistic action and higher control effect than a single agent. The seed treatment dispersible powder can be used for directly treating seeds, avoids the bacteria carrying of the seeds, has high sterilization efficiency and small dosage, avoids the drug resistance of diseases, prolongs the drug duration, is beneficial to the sustainable development of the environment, and has special effect on the late blight of potatoes through verification.

Description

Seed treatment dispersible powder containing dimethomorph and propamocarb and application thereof

Technical Field

The invention relates to a seed treatment dispersible powder containing dimethomorph and propamocarb and application thereof, belonging to the technical field of pesticides.

Background

Dimethomorph (chemical name is (E, Z) -4- [3- (4-chlorphenyl) 3- (3, 4-dimethoxyphenyl) acryloyl ] morpholine) is a specific oomycete fungus killing bactericide, has the action characteristic of destroying the formation of a cell wall membrane, has action on all stages of the life history of oomycetes, is particularly sensitive in the formation stage of sporangium and oospore, is inhibited at an extremely low concentration (<0.25 mu g/ml), has no cross resistance with phenylamide medicaments, is widely used for preventing and treating diseases caused by oomycetes of trichotoma, such as vegetable downy mildew, epidemic disease, seedling damping-off, tobacco shank and the like, and has systemic activity. Dimethomorph alone has a relatively high risk of resistance.

Propamocarb (chemical name: 3-dimethylamino propyl carbamate propyl ester) belongs to an aliphatic bactericide, is low in toxicity and safe, has a good local systemic effect, can be quickly absorbed by root systems and upwards conveyed to the whole plant after soil treatment, and can be quickly absorbed by leaves to play a role in protection after stem and leaf spraying treatment. The propamocarb has the action mechanism of inhibiting the synthesis of phosphoric acid and fatty acid of germ cell membrane components, and inhibiting the growth and spread of hyphae, the formation of sporangia and the germination of spores. Propamocarb is a broad-spectrum bactericide, is particularly effective on algae class fungi, has good killing effect on fungus such as tow mold, plenophora, peronospora, phytophthora, pythium and the like, and can also be used as a dipping treatment and seed protective agent.

The potato late blight is caused by phytophthora infestans (A), (B), (CPhytophthora infestans) The main diseases caused by the potato in the main producing area of the world are listed as the most important food crop diseases in the world at present, which cause great loss to the food production in the world. The main primary infection sources of the potato late blight are diseased potato seeds, and the fumigation sterilization, seed potato selection, pre-sowing treatment and the like of the potato seeds can reduce the occurrence of the late blight, but the methods can not completely solve the problem of the bacterial infection of the potato seeds. The seed coating agent is used for coating the seed potatoes, a protective medicine film can be formed on the surfaces of the seed potatoes, the medicine film can kill the potato late blight germs on the surfaces and shallow layers of the seed potatoes and prevent the late blight germs hidden in the deep layers of the seed potatoes from expanding outwards, so that the pathogenic bacteria on the seed potatoes are eliminated or greatly reduced, the residual effective period of the agent is prolonged, and the occurrence of the late blight is controlled.

Although dimethomorph and propamocarb have a certain prevention and treatment effect on epidemic diseases, a large amount of single bactericide is used for a long time, so that the diseases are easy to generate drug resistance, the dosage is increased, the prevention effect is reduced, the effective period is shortened, the environment sustainable development is not facilitated, the generation of drug resistance can be delayed by compounding the bactericide, the bactericidal spectrum can be expanded, and the prevention and treatment effect is improved.

Disclosure of Invention

The invention aims to provide the seed treatment dispersible powder containing dimethomorph and propamocarb, which has a good sterilization effect and particularly has a good effect of killing potato late blight bacteria.

The invention also provides application of the seed treatment dispersible powder containing dimethomorph and propamocarb, in particular to application of the seed treatment dispersible powder in preventing and treating potato late blight.

The invention is realized by the following technical scheme:

a seed treatment dispersible powder (WS) containing dimethomorph and propamocarb, which comprises the following components in percentage by weight: 10-80% of active pharmaceutical ingredients, 4-10% of dispersing agents, 1-5% of wetting agents, 1-10% of film forming agents, 1-10% of anti-caking agents, 0.1-5% of coloring agents and the balance of fillers; the active ingredients of the medicine are dimethomorph and propamocarb.

In the dispersible powder for seed treatment of the invention, the propamocarb refers to propamocarb technical and water-soluble inorganic salt thereof, and is preferably propamocarb hydrochloride.

In the seed treatment dispersible powder, the weight ratio of the medicinal active ingredients of dimethomorph and propamocarb is 1:0.1-10, preferably 1:0.2-5, and more preferably 1: 0.5-2. When the optimized weight ratio is adopted, the sterilization effect of the seed treatment dispersible powder is better.

Further, the seed treatment dispersible powder comprises the following components in percentage by weight: 40-70% of medicinal active ingredients, 4-10% of dispersing agents, 1-5% of wetting agents, 1-10% of film forming agents, 1-10% of anti-caking agents, 0.1-5% of coloring agents and the balance of fillers.

Further, the seed treatment dispersible powder comprises the following components in percentage by weight: 10-80% of active pharmaceutical ingredients (preferably 40-70%), 7-8% of dispersing agent, 2-3% of wetting agent, 3-5% of film forming agent, 3-5% of anti-caking agent, 0.5-2% of coloring agent and the balance of filler.

Further, the dispersing agent is one or more of calcium lignosulfonate, maleic acid-acrylic acid copolymer salt, polyoxyethylene-polyoxypropylene block copolymer, sodium alkylphenol sulfonate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfonate, sodium naphthalene sulfonate formaldehyde condensate and sodium polycarboxylate, and is preferably a mixture of sodium naphthalene sulfonate formaldehyde condensate and calcium lignosulfonate in a mass ratio of 1: 2-5.

Further, the wetting agent is one or more of sodium dodecyl sulfate, sodium tetradecyl sulfate, sodium dodecyl benzene sulfonate, sodium alkyl naphthalene sulfonate, sodium a-olefin sulfonate, sodium alkylphenol polyoxyethylene ether sulfate, sodium lignosulfonate, nekal BX, fatty acid sulfate and fatty acid ester sulfate, and preferably a mixture of the sodium dodecyl sulfate and the sodium lignosulfonate in a mass ratio of 3-5: 2.

Further, the film forming agent is one or more of PVP (polyvinylpyrrolidone), CMC (carboxymethyl cellulose), PVA (polyvinyl alcohol), hydroxypropyl methyl cellulose and magnesium aluminum silicate, and the mass ratio is preferably 1:0.5-2 of a mixture of CMC and PVA.

Further, the anti-blocking agent is one or more of white carbon black, talcum powder and bentonite, and preferably white carbon black.

Further, the colorant is one or more of acid scarlet, agricultural deep red, alkaline rose essence and aqueous rose red, and is preferably agricultural deep red.

Further, the filler is one or more of kaolin, attapulgite, diatomite, starch, light calcium carbonate, urea and ammonium sulfate, and is preferably diatomite.

When the dispersing agent, the wetting agent, the film forming agent, the anti-caking agent, the coloring agent and the filler are selected from the components, the obtained seed treatment dispersible powder has better performances such as thermal stability, film forming property, shedding rate and the like.

The invention also provides a preparation method of the dimethomorph and propamocarb-containing seed treatment dispersible powder, which comprises the following steps: the dimethomorph, the propamocarb, the dispersant, the wetting agent, the film-forming agent, the anti-caking agent, the colorant and the filler are uniformly mixed in a mixer, crushed to the particle size of 10-30 mu m by a jet mill and then uniformly mixed to obtain the bactericide.

The invention also provides application of the seed treatment dispersible powder containing dimethomorph and propamocarb in controlling fungal diseases of potatoes, and preferably controlling late blight of potatoes. The dimethomorph and the propamocarb are compounded, so that the sterilization effect is improved, the drug resistance is avoided, and the bactericidal composition has a good effect on potato fungal diseases, particularly late blight.

In the application, the use method of the seed treatment dispersible powder comprises the following steps: and (4) dressing the seed potatoes with the seed treatment dispersible powder. The specific operation method comprises the following steps: and adding water to dilute the seed treatment dispersible powder, and then mixing the seed treatment dispersible powder with the seed potatoes to ensure that the seed treatment dispersible powder is uniformly attached to the surfaces of the seed potatoes.

The invention has the beneficial effects that:

1. according to the invention, dimethomorph and propamocarb are compounded and prepared into the seed treatment dispersible powder, and the dimethomorph and the propamocarb belong to two bactericides with different action mechanisms, and the dimethomorph and the propamocarb are mutually mixed and do not generate conflict, so that the dimethomorph and the propamocarb have good synergistic effect and higher control effect than a single agent;

2. the seed treatment dispersible powder can be used for directly treating seeds, avoids the bacteria carrying of the seeds, has high sterilization efficiency and small dosage, avoids the drug resistance of diseases, prolongs the drug duration, is beneficial to the sustainable development of the environment, and has special effect on the late blight of potatoes through verification.

Detailed Description

The present invention will be further described with reference to the following examples, but the present invention is not limited thereto. Unless otherwise specified, the percentages in the following examples are percentages by weight.

The embodiment of the invention adopts a method combining indoor toxicity measurement and field test. Firstly, through indoor toxicity measurement, the Synergistic Ratio (SR) of dimethomorph and propamocarb compounded according to a certain proportion is determined, the SR < 0.5 is antagonistic action, the SR < 0.5 and less than or equal to 1.5 are additive action, and the SR > 1.5 is synergistic action, and then field tests are carried out on the basis. Wherein, propamocarb is selected from propamocarb hydrochloride.

Dimethomorph and propamocarb hydrochloride compounded indoor toxicity determination method for potato late blight bacteria

The test agents were provided by Shandong Weifang Runfeng Feng chemical company Limited.

After the effective inhibition concentration range of each medicament is determined through pre-test, each medicament is respectively treated by a series of concentration gradients according to the content of effective components, and clear water is used as a reference. The toxicity of the medicament on the potato late blight is determined by adopting a hypha growth rate method according to 'pesticide indoor bioassay test standard bactericide'. And measuring the colony diameter by a cross method after 72h, and calculating the net growth amount and the hypha growth inhibition rate of each treatment.

Converting the hypha growth inhibition rate into a probability value (y), converting the drug solution concentration (mu g/mL) into a logarithm value (x), obtaining a virulence regression equation (y is a + bx) by a least square method, and calculating the EC of each drug₅₀The value is obtained. Meanwhile, the combined Synergistic Ratio (SR) of the two medicaments in different proportions is calculated according to the Wadley method, the antagonism is achieved when the SR is less than 0.5, the addition effect is achieved when the SR is more than or equal to 0.5 and less than or equal to 1.5, and the synergism is achieved when the SR is more than 1.5. The calculation formula is as follows:

the test results are shown in table 1:

as shown in Table 1, the EC of dimethomorph and propamocarb hydrochloride on late blight bacteria₅₀0.189mg/L and 5.524mg/L respectively, and the toxicity of the dimethomorph is obviously higher than that of the propamocarb hydrochloride. The dimethomorph and the propamocarb hydrochloride are mixed in the range of 1:0.1-10 to show synergistic effect, the preferable proportion is in the range of 1:0.2-5, and when the proportion is 1:0.5-2, the synergistic effect is most remarkable.

The following examples are given by way of illustration only and are not intended to limit the scope of the present invention, in order to make the present invention more clear to those skilled in the art. In the following examples, the contents of the respective components are given in weight percent.

Example 160% Dimethomorph Pericarb hydrochloride seed treatment dispersible powders

The formula is as follows: 30% of dimethomorph, 30% of propamocarb hydrochloride, 2% of naphthalene sulfonic acid formaldehyde condensate sodium salt, 6% of calcium lignosulfonate, 1.8% of sodium dodecyl sulfate, 1.2% of sodium lignosulfonate, 1.5% of CMC, 1.5% of PVA, 5% of white carbon black, 1.5% of agricultural deep red and 100% of diatomite.

The preparation method comprises the following steps: the propamocarb hydrochloride, the dimethomorph, the dispersing agent, the wetting agent, the film-forming agent, the anti-caking agent, the coloring agent and the filler are uniformly mixed in a mixer, crushed to the particle size of 10-30 mu m by an airflow crusher and then uniformly mixed to obtain the dimethomorph-propamocarb hydrochloride seed treatment dispersible powder.

Example 210% Dimethomorph Pericarb hydrochloride seed treatment dispersible powders

The formula is as follows: dimethomorph 7%, propamocarb hydrochloride 3%, naphthalene sulfonic acid formaldehyde condensate sodium salt 1.75%, calcium lignosulfonate 5.25%, sodium dodecyl sulfate 1.2%, sodium lignosulfonate 0.8%, CMC 2.5%, PVA 2.5%, white carbon black 3%, agricultural deep red 2% and diatomite added to 100%. The preparation method is the same as example 1.

Example 333% Dimethomorph Pericarb hydrochloride seed-treated dispersible powders

The formula is as follows: 11% of dimethomorph, 22% of propamocarb hydrochloride, 2% of naphthalene sulfonic acid formaldehyde condensate sodium salt, 6% of calcium lignosulfonate, 1.8% of sodium dodecyl sulfate, 1.2% of sodium lignosulfonate, 1.5% of CMC, 1.5% of PVA, 5% of white carbon black, 1.5% of agricultural deep red and 100% of diatomite. The preparation method is the same as example 1.

Example 440% Dimethomorph Peramocarb hydrochloride seed treatment dispersible powders

The formula is as follows: 33.3 percent of dimethomorph, 6.7 percent of propamocarb hydrochloride, 2 percent of naphthalene sulfonic acid formaldehyde condensate sodium salt, 6 percent of calcium lignosulfonate, 1.8 percent of sodium dodecyl sulfate, 1.2 percent of sodium lignosulfonate, 1.5 percent of CMC, 1.5 percent of PVA, 5 percent of white carbon black, 0.5 percent of agricultural deep red and the addition of diatomite to 100 percent. The preparation method is the same as example 1.

Example 551% Dimethomorph Pericarb hydrochloride seed treatment dispersible powders

The formula is as follows: 8.5 percent of dimethomorph, 42.5 percent of propamocarb hydrochloride, 2 percent of naphthalene sulfonic acid formaldehyde condensate sodium salt, 6 percent of calcium lignosulfonate, 1.8 percent of sodium dodecyl sulfate, 1.2 percent of sodium lignosulfonate, 1.5 percent of CMC, 1.5 percent of PVA, 5 percent of white carbon black, 1.5 percent of agricultural deep red and 100 percent of diatomite. The preparation method is the same as example 1.

Example 670% Dimethomorph Pericarb hydrochloride seed treatment dispersible powders

The formula is as follows: 6.4 percent of dimethomorph, 63.6 percent of propamocarb hydrochloride, 2 percent of naphthalene sulfonic acid formaldehyde condensate sodium salt, 6 percent of calcium lignosulfonate, 1.8 percent of sodium dodecyl sulfate, 1.2 percent of sodium lignosulfonate, 1.5 percent of CMC, 1.5 percent of PVA, 5 percent of white carbon black, 1.5 percent of agricultural deep red and 100 percent of diatomite. The preparation method is the same as example 1.

Example 710% Dimethomorph Peramocarb hydrochloride seed treatment dispersible powders

The formula is as follows: dimethomorph 7%, propamocarb hydrochloride 3%, maleic acid-acrylic acid copolymer salt 4%, sodium tetradecyl sulfate 3%, sodium dodecyl sulfate 0.6%, sodium alpha-olefin sulfonate 0.4%, PVP 3%, white carbon black 1%, agricultural dark red 0.1%, and kaolin added to 100%. The preparation method is the same as example 1.

EXAMPLE 833% Dimethomorph Peramocarb hydrochloride seed-treating dispersible powders

The formula is as follows: 11% of dimethomorph, 22% of propamocarb hydrochloride, 3% of naphthalenesulfonic acid formaldehyde condensate sodium salt, 7% of polyoxyethylene-polyoxypropylene block copolymer, 5% of sodium dodecyl benzene sulfonate, 1% of PVA, 3% of hydroxypropyl methyl cellulose, 7% of talcum powder, 0.9% of agricultural dark red and the total amount of attapulgite added to 100%. The preparation method is the same as example 1.

Example 960% Dimethomorph Peramocarb hydrochloride seed treatment dispersible powders

The formula is as follows: 30% of dimethomorph, 30% of propamocarb hydrochloride, 2% of sodium polycarboxylate, 4% of sodium alkyl phenol sulfonate, 1% of sodium dodecyl sulfate, 1% of sodium alkyl naphthalene sulfonate, 10% of hydroxypropyl methyl cellulose, 2% of white carbon black, 1.3% of aqueous rose bengal, 10% of urea and the balance of starch to 100%. The preparation method is the same as example 1.

Example 1060% Dimethomorph Peramocarb hydrochloride seed treatment dispersible powders

The formula is as follows: 30% of dimethomorph, 30% of propamocarb hydrochloride, 2% of alkylphenol polyoxyethylene ether formaldehyde condensate sulfonate, 4.5% of calcium lignosulfonate, 0.5% of alkylphenol polyoxyethylene ether sodium sulfate, 0.5% of fatty acid ester sulfate, 8% of magnesium aluminum silicate, 8% of bentonite, 3% of aqueous rose bengal and the balance of light calcium carbonate to 100%. The preparation method is the same as example 1.

Example 1160% Dimethomorph Pericarb hydrochloride seed-treating dispersible powders

The formula is as follows: 30% of dimethomorph, 30% of propamocarb hydrochloride, 3% of alkylphenol polyoxyethylene ether formaldehyde condensate sulfonate, 1% of naphthalenesulfonic acid formaldehyde condensate sodium salt, 1% of polycarboxylic acid sodium salt, 1.8% of nekal BX, 1.2% of fatty acid sulfate, 0.5% of magnesium aluminum silicate, 0.5% of PVP, 10% of talcum powder, 5% of acid scarlet and 100% of ammonium sulfate. The preparation method is the same as example 1.

Example 1280% Dimethomorph Pericarb hydrochloride seed treatment dispersible powders

The formula is as follows: 40% of dimethomorph, 40% of propamocarb hydrochloride, 1% of polyoxyethylene-polyoxypropylene block copolymer, 3% of calcium lignosulphonate, 0.3% of sodium alkylphenol polyoxyethylene ether sulfate, 0.7% of fatty acid ester sulfate, 2% of magnesium aluminum silicate, 2% of bentonite, 0.5% of alkaline rose essence and light calcium carbonate added to 100%. The preparation method is the same as example 1.

Comparative example 60% Dimethomorph Pericarb hydrochloride seed-treating dispersible powder

The formula is as follows: 30% of dimethomorph, 30% of propamocarb hydrochloride, 2% of naphthalene sulfonic acid formaldehyde condensate sodium salt, 6% of calcium lignosulfonate, 1.8% of sodium dodecyl sulfate, 1.2% of sodium lignosulfonate, 1.5% of agricultural scarlet and diatomite which are added to 100%. The preparation method is the same as example 1.

The quality indexes of the dimethomorph and propamocarb hydrochloride seed-treated dispersible powders prepared in the above examples and comparative examples are tested, and the results are shown in the following table 2. The invention tests the suspension rate, the film forming time, the shedding rate and the uniformity of the seed treatment dispersible powder according to the method in NY 621-2002; the seed-treated dispersible powders were tested for flowability after pressurized storage according to the method of CIPAC MT 46.1.1.

As can be seen from the data in Table 2, the quality index of the products of examples 1-6 using the preferred adjuvants is better than that of examples 7-12, and the preferred adjuvants play a key role in the product quality.

Experiment of drug effect

The dimethomorph propamocarb hydrochloride seed treatment dispersible powder prepared in the above examples and comparative examples is subjected to a pesticide effect test for controlling the potato late blight. The experiment is arranged to be carried out in Gansu Bingmao county, and the control medicament is 50% dimethomorph water dispersible granules (purchased from the market) and 722g/L propamocarb hydrochloride aqueous solution (purchased from the market).

The test was performed with 16 treatments, i.e., drug control, blank control, and drug treatment, each of which was repeated 3 times.

Medicament control treatment: the drug is applied at the early stage of the late blight of the potato, stem and leaf spraying treatment is carried out by using a Gongnong-16 knapsack manual sprayer, 600kg of water is added into a preparation per hectare to prepare a drug solution, and a contrast drug is 50% dimethomorph water dispersible granule and 722g/L propamocarb hydrochloride water solution;

medicament treatment: the seed potatoes were respectively dressed with the agents of examples and comparative examples. The seed potato seed dressing method comprises the following steps: adding water into the agent for uniform dilution, spreading the potatoes uniformly (cutting the seed potatoes into potato blocks with single eyes weighing about 30-40 g) after spreading a plastic cloth on the ground, uniformly spraying the seed dressing agent onto the seed potatoes with 1 liter of water per mu of the seed potatoes according to the dosage, and quickly stirring while spraying until the liquid medicine is uniformly attached to the surfaces of the potatoes. Air-drying for half a day to one day and then sowing.

The investigation method refers to GB/T17980.34-2000. The control effect calculation method comprises the following steps:

the control area is a blank control area and does not spray a medicament.

During the test, the preparation of the invention has no adverse effect on the potatoes in the test application range, and the test results are shown in the following table 3:

as can be seen from Table 3, the dimethomorph and propamocarb hydrochloride seed treatment dispersible powder can effectively prevent and treat the potato late blight through the selection of the active pharmaceutical ingredients and the auxiliary materials, and the prevention and treatment effects are superior to those of the control medicament. The control effect of the embodiment using the preferable auxiliary agent is obviously superior to that of other embodiments, and the control effect on the potato late blight reaches more than 87%; the control effect of other examples is more than 80 percent and is also better than that of a control medicament.

Claims

1. A seed treatment dispersible powder containing dimethomorph and propamocarb is characterized in that: comprises the following components in percentage by weight: 10-80% of a pharmaceutical active ingredient, 7-8% of a dispersant, 2-3% of a wetting agent, 3-5% of a film forming agent, 3-5% of an anti-caking agent, 0.5-2% of a colorant and the balance of a filler; the active ingredients of the medicine are dimethomorph and propamocarb, or water-soluble inorganic salts of dimethomorph and propamocarb; the weight ratio of dimethomorph to propamocarb or propamocarb water-soluble inorganic salt is 1: 0.1-10;

the dispersing agent is a mixture of sodium naphthalene sulfonate formaldehyde condensate and calcium lignosulfonate in a mass ratio of 1: 2-5; the wetting agent is a mixture of sodium dodecyl sulfate and sodium lignin sulfonate in a mass ratio of 3-5: 2; the film forming agent is prepared from the following components in percentage by mass of 1:0.5-2 of a mixture of CMC and PVA; the anti-caking agent is white carbon black; the colorant is agricultural dark red; the filler is diatomite.

2. The seed treatment dispersible powder of claim 1, characterized by: the water-soluble inorganic salt of propamocarb is propamocarb hydrochloride.

3. The seed treatment dispersible powder of claim 1, characterized by: the weight ratio of the dimethomorph to the propamocarb or the water-soluble inorganic salt of the propamocarb is 1: 0.2-5.

4. The seed treatment dispersible powder of claim 3, characterized by: the weight ratio of the dimethomorph to the propamocarb or the water-soluble inorganic salt of the propamocarb is 1: 0.5-2.

5. The seed treatment dispersible powder of claim 1, characterized by: comprises the following components in percentage by weight: 40-70% of medicinal active ingredients, 7-8% of dispersing agents, 2-3% of wetting agents, 3-5% of film forming agents, 3-5% of anti-caking agents, 0.5-2% of coloring agents and the balance of fillers.

6. Use of a seed-treatment dispersible powder comprising dimethomorph and propamocarb according to any one of claims 1 to 5 for controlling fungal diseases in potatoes.

7. Use according to claim 6, characterized in that: the fungal disease is late blight.