CN106852332A - Bactericidal composition containing SYP-Z048 - Google Patents

Bactericidal composition containing SYP-Z048 Download PDF

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Publication number
CN106852332A
CN106852332A CN201510897871.2A CN201510897871A CN106852332A CN 106852332 A CN106852332 A CN 106852332A CN 201510897871 A CN201510897871 A CN 201510897871A CN 106852332 A CN106852332 A CN 106852332A
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syp
active compound
water
bactericidal composition
disease
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陈宇
陈召亮
迟会伟
卢伟平
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Sinochem Agro Co Ltd
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Sinochem Agro Co Ltd
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/50—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids the nitrogen atom being doubly bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention belongs to pesticide field, and in particular to a kind of containing SYP-Z048 and composition and its application of the methoxy acrylic bactericide as active component.Said composition also includes filler and auxiliary agent.Wherein described methoxy acrylic be selected from it is following any one：Alkene oxime amine, kresoxim-methyl, azoles amine bacterium ester, ZJ0712, SSF 126 or SYP-3375.Said composition has good prevention effect to the plurality of plant diseases caused by oomycetes, sac fungus, basidiomycetes and Fungi Imperfecti, can effectively control the generation and harm of the plant diseases such as graw mold of tomato, gray mold of cucumber, powdery mildew of cucumber, cucumber anthracnose, leaf muld of tomato, alternaria leaf spot of apple, wheat scab, cotton wilt, banana Panama disease, banana blight, bakanae disease of rice, watermelon blight.Said composition wide sterilization spectrum, with obvious synergistic effect, can reduce dosage, reduce drug cost, delay germ to produce and development the resistance of single medicine.

Description

Bactericidal composition containing SYP-Z048
Technical field
The invention belongs to pesticide field, and in particular to a kind of composition containing SYP-Z048 Yu methoxy acrylic And its application.Said composition is used to prevent and treat head blight, leaf mold, anthracnose, early blight, the grey mold of Cereal, fruit tree or vegetables Various fungal diseases such as disease, late blight.
Background technology
Plant disease is divided into infectivity and the class of non-infective two, and in all infectious diseases, fungal disease quantity is most For various, more than the 70% of all disease quantity is accounted for.Fungal disease includes sac fungus, basidiomycetes, Fungi Imperfecti, Oomycete disease Evil, causes that root-rot, stem rot, fruit (fringe) be rotten, branch is withered and the symptom such as tikka more.After crop is caused harm by fungal infection, not only The quality of influence crop, and the yield of crop is influenceed, so as to cause economic loss, jeopardize the processing industry with agricultural product as raw material And food industry.
SYP-Z048 (English common name：Pyrisoxazole it is) that the pyridyloxazole quinoline class that Shenyang Chemical Engineering Inst develops is new Type disinfectant use in agriculture (compound patent ZL99113093.6).SYP-Z048 chemical name is：N- methyl -3- (4- chlorine) benzene The oxazoline of base -5- methyl -5- pyridine -3- methyl -, molecular formula is C16H17ClN2O；Its CAS accession number [847749-37-5], knot Structure formula is as follows：
The SYP-Z048 mechanism of action is to suppress the synthesis of plant pathogenic fungi sterol.By with sterol biosynthesis approach in Various enzymes are had an effect, and disturb or block the biosynthesis of ergosterol, are destroyed the structure of disease fungus cell membrane and are reached suppression Bacterium and sterilized purpose.SYP-Z048 structure is novel, and the mode of action is unique, and wide sterilization spectrum, bactericidal activity is high, has to plant disease Preventive and therapeutic action, is widely used in preventing and treating corps diseases, various to what is caused by sac fungus, basidiomycetes and Fungi Imperfecti Plant disease has good prevention effect, can effectively control graw mold of tomato, gray mold of cucumber, leaf muld of tomato, apple spot The generation of the plant diseases such as point defoliation, wheat scab and harm.Meanwhile, SYP-Z048 also has good to soil-borne disease Preventive effect.
Methoxy acrylic bactericide be based on natural antibiotics stobiluronA be lead compound exploitation it is new Type bactericide, is energy formation inhibitor, is also extremely potential a kind of novel agricultural sterilization in current agricultural chemicals circle field Agent.The common structural unit of methoxy acrylic bactericide is (E)-'beta '-methoxy acrylic acid ester units, and the unit is at α It is connected with the other parts of molecule.Methoxy acrylic bactericide acts on answering on mitochondria internal respiration electron transport chain Compound III (Cyt bc1 compounds), is incorporated into the Qo sites of Cyt b in compound, and blocking electronics is passed from Cyt b to Cyt c1 Pass, the generation of ATP is prevented, so as to suppress or kill fungi.Methoxy acrylic bactericide can effectively prevent and treat sac fungus, load The fungus-caused disease such as daughter bacteria, Fungi Imperfecti and oomycetes.Methoxy acrylic bactericide is included but is not limited to, alkene oxime bacterium Amine, azoles amine bacterium ester, kresoxim-methyl, ZJ0712, SSF 126, SYP-3375, pyraclostrobin, trifloxystrobin, fluoxastrobin, pyridine oxygen Bacterium ester, Fluoxastrobin, mepanipyrim, orysastrobin or pyraoxystrobin etc..
Alkene oxime amine (Fenaminstrobin) is that (compound is special for the new type bactericide of Shenyang Chemical Engineering Inst's independent research Profit ZL00110143.9), chemical name：N- methyl -2- [2- ((((1- methyl -3- (2,6- dichlorophenyls) -2- acrylic) Amino) epoxide) methyl) phenyl]-2- methoxyimino acetic amides, CAS registration numbers are 1257598-43-8.With following knot Structure formula：
Alkene oxime amine is respectively provided with preferable preventive and therapeutic effect to the plurality of plant diseases on the crops such as cereal, fruit tree, vegetables, especially It is notable to powdery mildew, rust, leaf spot preventive effect.Its wide sterilization spectrum, activity are high, with prevention and therapeutic action and and ring Border biology has good compatibility.To fungus-caused various by mastigomycetes, zygomycete, sac fungus, basidiomycetes and Fungi Imperfecti etc. Plant disease has good preventive effect.Alkene oxime amine is mitochondrial respiratory inhibitor, suppresses mitochondrial electron transmission.Alkene oxime bacterium Amine can also delay paddy rice aging, with " health care " effect.
The general entitled Pyrametostrobin of azoles amine bacterium ester (SYP-4155) English, is the limited public affairs of Shenyang Chemical Engineering Inst Take charge of the methoxy acrylic bactericide (compound patent ZL200510046515.6) of independent research.The series bactericidal agent is Mitochondrial respiratory inhibitor, i.e., combined by the Qo sites with Ctyb in mitochondrial electron transport chain, prevents the electricity of compound III Son transmission, so that mitochondrial respiratory is obstructed, prevents energy synthesis, plays bactericidal action.Its chemical structural formula is：
Azoles amine bacterium ester has broad spectrum activity, to the most plants disease caused by basidiomycetes, sac fungus, zygomycete and Fungi Imperfecti Evil has good preventive and therapeutic effect.To cucumber anthracnose, canker of apple fruit, graw mold of tomato, rice sheath blight disease, rape sclerotium The inhibitions such as disease, wheat powdery mildew, powdery mildew of cucumber are excellent.With excellent protection, therapeutic activity；It is simultaneously again interior well Inhale conductibility.The photostability of azoles amine bacterium ester is also preferable, and resistance of rainwater washing against.
Kresoxim-methyl (kresoxim-methyl), chemical name is (E) -2- methoxyiminos-[2- (o-methyl-benzene epoxide first Base) phenyl] methyl acetate, its structure be for：
Kresoxim-methyl is a kind of brand-new Plant Disease Management of bio-mimetic syntheses based on natural antibiotics stobiluronA Product.To crop and Environmental security, with high bactericidal activity, a kind of new sterilized standard is gradually established in the whole world.It Produce the disease of resistance highly effective to other bactericide.Not only there is the bactericidal activity of wide spectrum, while with good guarantor Shield and therapeutic action.The bactericide no interactions resistance conventional with other, and it is more long than the conventional sterilization agent lasting period.Choosing with height Selecting property, it is substantially pollution-free to environment to crop, people and animals and beneficial organism safety.
Kresoxim-methyl can suppress Spores intrusion, with good protection activity, vegetables, fruit tree, flower effectively be controlled comprehensively The fungus-caused multiple diseases such as Fungi Imperfecti, sac fungus, basidiomycetes, Oomycete are had by the various fungal diseases of the plants such as grass It is active well, such as：The diseases such as uncinula necator, wheat rust, potato blight, pumpkin epidemic disease, rice blast are especially right Powdery mildew of strawberry, melon powdery mildew, powdery mildew of cucumber, pear scab special efficacy.
ZJ0712 is a kind of wide sterilization spectrum, and bactericidal activity is high, with good protection, treatment, osmosis and resistance to Drench with rain, the lasting period is long.Its mechanism of action is exactly by suppressing mitochondrial respiration, destroying the energy synthesis of germ.Chemistry It is entitled：(E) -2- [2- (2,5- dimethyl phenoxy)-benzylidene] -3- methoxy-methyl acrylates, its chemical structural formula For：
ZJ0712 is to the powdery mildew (such as cucurbits powdery mildew, apple mildew) of various crops, rust (such as apple rust Disease, rust of pear etc.), downy mildew (grape and cucumber downy mildew etc.), anthracnose (such as cucumber, watermelon and mango anthracnose) all tables Reveal excellent prevention effect, realize the multiple diseases for spraying by a kind of bactericide and mixing generation on control crop simultaneously.
ZJ0712 is a simultaneous bactericide controlled of prevention, while the photosynthesis of plant strengthens after being sprayed through medicament, energy Crop is set to keep verdure in a long time, so as to improve the yield and quality of crop.
SSF 126 (Metominostrobin), molecular formula：C16H16N2O3, chemical name：(E) -2- methoxyl groups imines Base-N- methyl -2- (2- Phenoxyphenyls) acetamide.Structural formula：
SSF 126 is methoxy acrylic bactericide, is that a kind of new wide spectrum, protection and therapeutic activity have concurrently Systemic fungicide.It is mainly used in preventing and treating rice blast etc., is being uninfected by or early stage is applied, dosage is 500- 2000 grams of active ingredient/hectares.The mechanism of action：Mitochondrial respiratory inhibitor is by the electro transfer between cytochrome b and C1 Suppress mitochondrial breathing.14- demethylations enzyme inhibitor, benzamides, dicarboxylic dihydrazides amine and benzimidazole are produced The bacterial strain of resistance is effective.With protecting, treat, root out, permeate, systemic activity.To crop safety under recommended dose.
SYP-3375 is to develop methoxy acrylic bactericide (compound patent number by Shenyang Chemical Engineering Inst ZL200310105079.6).With immune, prevention, treatment, increasing both production and income effect.It is the anti-whole nation to apple tree canker special efficacy Control the most authoritative medicament of rot.Wide sterilization spectrum, to melon fruits and vegetables, fruit tree downy mildew, late blight, scab, anthracnose, Leaf mold is effective；Simultaneously to ring spot, anthracnose, cotton wilt, paddy rice pestilence, withered line disease, root rotof flax, corn is small Pinta is also effective.The chemical name of SYP-3375 is (E) -2- (2- ((3- butyl -4- methyl-coumarins -7- bases-epoxide) first Base) phenyl) -3- methoxy-methyl acrylates, its chemical structural formula is:
Although using SYP-Z048 or methoxy acrylic bactericide in the prior art, pyridine bacterium is single use Oxazole or methoxy acrylic bactericide can cause fungicidal spectrum narrow, easily produce resistance, and use cost is high, very not The need for beneficial to extensive broad-spectrum sterilization in agricultural, therefore urgent need will develop new product to solve this technical problem.
Invention summary
For the problems of the prior art, SYP-Z048 and methoxy acrylic are contained present invention aim at providing The composition of bactericide, it is to be compounded the sterilization component of two kinds of different structures, the different mechanisms of action, to expand preventing and treating spectrum With raising drug effect, the drug-fast generation of pathogen and development can also be delayed, extend the service life of medicament.
The present composition has following remarkable result and advantage：
1. synergistic effect is obvious：Experiment shows SYP-Z048 with the composition of methoxy acrylic bactericide to disease With notable synergistic effect.
2. preventing and treating spectrum is expanded：SYP-Z048 can be prevented and treated in agricultural production with the composition of methoxy acrylic bactericide Multiple diseases.
3. use cost is reduced：Expand because compounding has to improve preventive effect, preventing and treating and compose, reduce access times, reducing makes Use cost.
4. the resistance to the action of a drug is delayed：Two kinds of composition compoundings of different mechanism of action, pathogen is not likely to produce the resistance to the action of a drug, delays cause of disease Generation and development of the thing to single dose resistance.
According to the one side of the application, this application provides a kind of bactericidal composition, the composition containing it is active into Divide SYP-Z048 and methoxy acrylic bactericide.
According to some implementation methods of the application, the prevention effect of the bactericidal composition is than any one separate constituent Prevention effect is higher by more than 10%.
According to some implementation methods of the application, the methoxy acrylic bactericide is selected from alkene oxime amine, azoles amine Any one in bacterium ester, kresoxim-methyl, ZJ0712, SSF 126 or SYP-3375.
According to some implementation methods of the application, the methoxy acrylic bactericide is selected from alkene oxime amine, azoles amine Any one in bacterium ester, kresoxim-methyl or SYP-3375.
According to some implementation methods of the application, the weight portion of the SYP-Z048 and methoxy acrylic bactericide Number is than being 1:80-80:1.
According to some implementation methods of the application, the weight portion of the SYP-Z048 and methoxy acrylic bactericide Number is than being 1:40-40:1.
According to some implementation methods of the application, the weight portion of the SYP-Z048 and methoxy acrylic bactericide Number is than being 1:20-20:1.
According to some implementation methods of the application, the SYP-Z048 is total with the weight of methoxy acrylic bactericide With the 1%-80% for accounting for the bactericidal composition gross weight.
According to some implementation methods of the application, the SYP-Z048 is total with the weight of methoxy acrylic bactericide With the 5%-65% for accounting for the bactericidal composition gross weight.
According to some implementation methods of the application, the bactericidal composition also includes filler, and preferably described filler is selected from height Ridge soil, diatomite, white carbon, attapulgite, bentonite, zeolite powder, resin, clay powder, wooden chaff, gelatinized starch, paraffin, methyl One or more in cellulose, carboxymethylcellulose calcium and carboxyethyl cellulose.
According to some implementation methods of the application, the bactericidal composition also includes auxiliary agent, and preferably described auxiliary agent is selected from agriculture One kind or many in newborn 1601#, alkylaryl sulfonates, lignosulfonates, lactic casein, mineral oil, gelatin, polyvinyl alcohol Kind.
According to some implementation methods of the application, the bactericidal composition is aqueous suspension agent, dispersibles oil-suspending agent, water and milk Agent, microcapsule formulations, microemulsion, wettable powder, soluble powder, water dispersible granules, Seed Treatment dispersant, suspension seed-coating agent Or Seed Treatment microcapsule suspending agent, preferably described bactericidal composition be aqueous suspension agent, dispersible oil-suspending agent, aqueous emulsion, moisture Shot agent, suspension seed-coating agent.
According to further aspect of the application, this application provides the use that the bactericidal composition is used for controlling plant diseases On the way.
According to some implementation methods of the application, the plant disease is by oomycetes, sac fungus, basidiomycetes and Fungi Imperfecti The plant disease for causing.
According to some implementation methods of the application, the plant disease includes graw mold of tomato, gray mold of cucumber, tomato morning Epidemic disease, leaf spot of peanut, powdery mildew of cucumber, cucumber anthracnose, leaf muld of tomato, alternaria leaf spot of apple, wheat scab, cotton Flower droop, banana Panama disease, banana blight, bakanae disease of rice, watermelon blight, citrus anthracnose.
According to further aspect of the application, this application provides a kind of method of controlling plant diseases, methods described will The bactericidal composition is applied to plant and planting region with controlling plant diseases.
According to some implementation methods of the application, the plant disease is by oomycetes, sac fungus, basidiomycetes and Fungi Imperfecti The plant disease for causing.
According to some implementation methods of the application, the plant disease includes graw mold of tomato, gray mold of cucumber, tomato morning Epidemic disease, leaf spot of peanut, powdery mildew of cucumber, cucumber anthracnose, leaf muld of tomato, alternaria leaf spot of apple, wheat scab, cotton Flower droop, banana Panama disease, banana blight, bakanae disease of rice, watermelon blight, citrus anthracnose.
According to some implementation methods of the application, the component for including the active component of the bactericidal composition is made preparation Using, or will include the active component of the bactericidal composition component bucket it is mixed after apply.
According to further aspect of the application, this application provides a kind of method for preparing the bactericidal composition, it is special Levy and be, the SYP-Z048, the methoxy acrylic bactericide and optional described filler or auxiliary agent are mixed Close.
Detailed description of the invention
Definition
Methoxy acrylic is the class compound with common structural unit (E)-'beta '-methoxy acrylic acid ester, should Unit is connected at α with the other parts of molecule.Methoxy acrylic bactericide can suppress mitochondrial breathing, blocking Electron transmission between disease fungus cytochrome b and c1, so as to play bactericidal action.Methoxy acrylic bactericide includes But it is not limited to, alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl, ZJ0712, SSF 126, SYP-3375, pyraclostrobin, oxime bacterium Ester, fluoxastrobin, ZEN 90160, Fluoxastrobin, mepanipyrim, orysastrobin or pyraoxystrobin etc..
Term " bactericidal composition " represent one or more containing antimicrobial effective amount described in compound or its agriculturally may be used The dynamic isomer of receiving, solvate, hydrate or salt, with other fillers and the mixture of auxiliary agent.By the compound system The standby purpose into bactericidal composition is in order to more easily to agricultural irrigation dispenser.
Term " active component ", is also called " active ingredient ", refers to the keyization that bactericidal action is played in the bactericidal composition Compound or its agriculturally acceptable dynamic isomer, solvate, hydrate or salt.In some implementation methods of the application In, the active component of the bactericidal composition includes SYP-Z048.In some implementation methods of the application, the Bactericidal composite The active component of thing includes methoxy acrylic bactericide.In some implementation methods of the application, the Bactericidal composite The active component of thing includes SYP-Z048 and methoxy acrylic bactericide.In some implementation methods of the application, institute The active component for stating bactericidal composition is made up of SYP-Z048 and methoxy acrylic bactericide.
Herein described bactericidal composition contains active component SYP-Z048 and methoxy acrylic bactericide, has Obvious synergistic effect.Term " synergistic effect " used herein, refers to that different chemical substances are being combined also known as " synergy " There is co-operating effect, the effect summation of the effect higher than each separate constituent of generation when using.
According to some implementation methods of the application, the prevention effect of the bactericidal composition is than any one separate constituent Prevention effect is higher by more than 10%, be for example higher by 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%th, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34%, 35%th, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%, 49%, 50%th, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%, 64%, 65%th, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 80%th, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%th, 96%, 97%, 98%, more than 99% or it is higher by 100%.
According to some implementation methods of the application, the weight portion of the SYP-Z048 and methoxy acrylic bactericide Number is than being 1:80-80:1, such as 1:79-79:1、1:78-78:1、1:77-77:1、1:76-76:1、1:75-75:1、1:70- 70:1、1:65-65:1、1:60-60:1、1:55-55:1、1:50-50:1、1:45-45:1、1:44-44:1、1:43-43:1、1: 42-42:1 or 1:41-41:1.According to some implementation methods of the application, the SYP-Z048 is killed with methoxy acrylic The ratio of weight and number of microbial inoculum is 1:40-40:1, such as 1:39-39:1、1:38-38:1、1:37-37:1、1:36-36:1、1:35- 35:1、1:34-34:1、1:33-33:1、1:32-32:1、1:31-31:1、1:30-30:1、1:29-29:1、1:28-28:1、1: 27-27:1、1:26-26:1、 1:25-25:1、1:24-24:1、1:23-23:1、1:22-22:1 or 1:21-21:1.According to this Some implementation methods of application, the SYP-Z048 is 1 with the ratio of weight and number of methoxy acrylic bactericide:20-20: 1, such as 1:19-19:1、1:18-18:1、1:17-17:1、1:16-16:1、1:15-15:1、1:14-14:1、1:13-13:1、 1:12-12:1、1:11-11:1、1:10-10:1、1:9-9:1、1:8-8:1、1:7-7:1、1:6-6:1、1:5-5:1、1:4-4: 1、1:3-3:1、1:2-2:1 or 3:20-20:3.According to some implementation methods of the application, the SYP-Z048 and methoxy propyl The ratio of weight and number of alkene bactericide of phosphate (phosphinium) ester is 1:80、1:75、1:70、1:65、1:60、1:55、1:50、1:45、1:40、1: 35、1:30、1:25、1:20、1:15、1:10、1:5、1:4、1:3、1:2、1:1、2:1、3:1、4:1、5:1、6:1、7:1、8:1、 9:1、10:1、15:1、20:1、25:1、30:1、35:1、40:1、45:1、50:1、55:1、60:1、65:1、70:1、75:1、80: 1。
According to some implementation methods of the application, the SYP-Z048 is total with the weight of methoxy acrylic bactericide With the 1%-80% for accounting for the bactericidal composition gross weight, such as 1%-79%, 1%-78%, 1%-77%, 1%-76%, 1%- 75%th, 1%-70%, 1%-65%, 2%-79%, 2%-78%, 2%-77%, 2%-76%, 2%-75%, 2%-70%, 2%-65%, 3%-79%, 3%-78%, 3%-77%, 3%-76%, 3%-75%, 3%-70%, 3%-65%, 4%- 79%th, 4%-78%, 4%-77%, 4%-76%, 4%-75%, 4%-70% or 4%-65%.According to the application some Implementation method, the SYP-Z048 accounts for the bactericidal composition gross weight with the weight summation of methoxy acrylic bactericide 5%-65%, such as 5%-64%, 5%-63%, 5%-62%, 5%-61%, 5%-60%, 5%-55%, 5%-50%, 5%-45%, 5%-40%, 5%-35%, 5%-30%, 5%-25%, 5%-20%, 5%-15%, 5%-10%, 10%- 65%th, 10%-60%, 10%-50%, 10%-40%, 10%-30%, 10%-20%, 15%-65%, 15%-60%, 15%-50%, 15%-40%, 15%-30%, 15%-20%, 20%-65%, 20%-60%, 20%-50%, 20%- 40%th, 20%-30%, 25%-65%, 25%-60%, 25%-50%, 25%-40%, 25%-30%, 30%-65%, 30%-60%, 30%-50%, 30%-40%, 35%-65%, 35%-60%, 35%-50%, 35%-40%, 45%- 65%th, 45%-60%, 45%-50%, 50%-65%, 50%-60%, 55%-65%, 55%-60%, 60%-65%, 5%-65%, 6%-65%, 7%-65%, 8%-65% or 9%-65%.It is described according to some implementation methods of the application The weight summation of SYP-Z048 and methoxy acrylic bactericide account for the bactericidal composition gross weight 1%, 2%, 3%, 4%th, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%th, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34%, 35%th, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%, 49%, 50%th, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%, 64%, 65%th, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 80%th, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%th, 96%, 97%, 98%, 99% or 100%.
Term " auxiliary agent " is Pesticide formulation or when using, auxiliary substance for improving medicament physicochemical property.Including Wetting agent, emulsifying agent, solvent, dispersant, sticker, stabilizer, synergist, safener, bleeding agent etc..Such as agriculture breast 1601#, One or more in alkylaryl sulfonates, lignosulfonates, lactic casein, mineral oil, gelatin, polyvinyl alcohol etc..
Term " filler " refers to for diluting active compound or absorption active compound, active compound is easy to mechanical crushing, increase dispersiveness, fill out Material can be for kaolin, diatomite, white carbon, attapulgite, bentonite, zeolite powder, resin, clay powder, wooden chaff, gelatinization are formed sediment One or more in powder, paraffin, methylcellulose, carboxymethylcellulose calcium and carboxyethyl cellulose.
Term " planting area " includes soil, the plant growth region and proximity after planting before planting Domain.
The compound described herein also tautomeric forms comprising the compound, such as ketoenol tautomerization Body.
Anhydride form of the compound described herein comprising the compound and non solvate form, also comprising the change The hydrate and solvate form thereof of compound.Term " solvate " refers to comprising the compound and one or many in the application The molecule of individual pharmaceutically acceptable solvent molecule (such as ethanol).According to some implementation methods of the application, in the solvate Can include such as 1-8 solvent molecule, such as 1-6,1-4,1-3,1-2,2-6,2-4,2-3,3-6 it is individual or 3-4.When wherein solvent is water, the solvate is hydrate.
Agriculturally acceptable salt refers to the acid-addition salts or base addition salts that the compound is formed.Form the acid of acid-addition salts Can be inorganic acid or organic acid, the inorganic acid including such as hydrochloric acid, hydrobromic acid, hydroiodic acid, phosphoric acid, nitric acid, sulfuric acid etc., institute Organic acid is stated including such as acetic acid, propionic acid, butyric acid, malonic acid, oxalic acid, glycolic, benzoic acid, citric acid, salicylic acid etc..Formed The alkali of base addition salts can be inorganic base or organic base, and the inorganic base is including such as sodium, potassium, calcium, magnesium, iron, zinc, aluminium, ammonium etc. Alkali, the organic base is including such as primary amine, secondary amine, tertiary amine, cyclammonium etc..
Term " dispenser ", " administration ", " giving " or " bestowing " refers to lead to the compound or bactericidal composition of doses Cross suitable application method and be applied to controlling object.
When applying, per hectare consumption can be 200-400g active components to bactericidal composition in the application, for example often Hectare consumption 200-350g, 200-300g, 200-250g, 250-400g, 250-350g, 250-300g, 300-400g, 300- 350g or 350-400g active components.Bactericidal composition in the application when applying, per hectare consumption can be about 200g, 250g, 300g, 350g or 400g active component.
" insecticide-applying way " includes but is not limited to any user known in the art such as water paddy irrigation, sprinkling, smearing Method.Herein described compound or bactericidal composition can give at any time.Such as described compound or bactericidal composition Can agricultural pest generation before, occur when or occur after use, for example can pest and disease damage occur before or send out after after About 1 hour, about 2 hours, about 4 hours, about 5 hours, about 8 hours, about 12 hours, about 24 hours, about 2 days, about 4 days, about 8 days, About 16 days, about 30 days or 1 month, dispenser in about 2 months.
Herein described bactericidal composition can be with first use, it is also possible to be used for multiple times.When used multiple times the notch, can with Every the mode dispenser of random time, such as subsequent dose and the interval of preceding dosage are for about 8 weeks, about 4 weeks, about 2 weeks, about 1 week, about 5 days, about 3 days, about 2 days, about 24 hours, about 12 hours, about 8 hours, about 6 hours, about 4 hours, about 3 hours, about 2 hours, about 1 Hour, about 30 minutes or less time.
Herein described bactericidal composition can be used alone, it is also possible to be used in mixed way with other suitable bactericide.Institute State be used in mixed way can be for example with other bactericide simultaneously use or successively use.When priority is used, can be appointed with being spaced The mode of meaning time is used.
Herein described bactericidal composition is used to prevent and treat graw mold of tomato, gray mold of cucumber, early blight of tomato, peanut tikka Disease, powdery mildew of cucumber, cucumber anthracnose, leaf muld of tomato, alternaria leaf spot of apple, wheat scab, cotton wilt, banana Panama disease, banana blight, bakanae disease of rice, watermelon blight etc., those skilled in the art should be recognized that this sterilized group Compound is not limited only to above-mentioned listed disease.
Those skilled in the art should be recognized that the bactericidal composition suitable dosage depend on Multiple factors, it is described because Element includes but is not limited to position, the age of object, the order of severity of pest and disease damage, the composition of bactericidal composition, the soil of pest and disease damage Proterties, administration time etc..
Herein described bactericidal composition can give various plants with dispenser, and the plant includes but is not limited to grain work Thing, such as wheat, paddy rice, corn, barley, highland barley, cereal, potato class etc.；Industrial crops, such as with oilseeds, peanut, flax, big Fiber crops, sunflower, sesame etc.；Vegetable crop, such as Chinese cabbage, cabbage, leek, celery, radish, carrot, garlic, green onion, sword bean, lettuce Bamboo shoot, capsicum, cucumber, tomato, caraway, various mushrooms etc.；Fruit tree, such as apple tree, pear tree, peach, jelly persimmon tree, orange Tree, Banana tree, apricot, cherry tree, Japanese plum, jujube tree, mulberry fruit tree etc.；Medicinal plant, such as Radix Angelicae Sinensis, honeysuckle, selfheal, people Ginseng etc.；And forage crop, tea tree etc..
Term " active compound " refers to the material medicine that uses in pesticidal preparations are produced, activity of the active compound comprising pesticidal preparations into Point.In general, active component constitutes about 90-100% in active compound.
In this application when " about " is used to modify numerical value, refer to the numerical value can fluctuate ± 10%, ± 9%, ± 8%, in the range of ± 7%, ± 6%, ± 5%, ± 4%, ± 3%, ± 2% or ± 1%.
Unless be otherwise noted in this application or otherwise clearly contradicted, in the context of description the application (including In the context of claim) term " one kind " that uses, " one ", " described ", " being somebody's turn to do " and " at least one " and similar refer to In generation, is interpreted to cover odd number and plural number.Unless be otherwise noted in this application or otherwise clearly contradicted, institute in the application The term "comprising" that uses, " having ", " including " and " containing " be interpreted open-ended term (i.e. " including but not limited to "). Unless be otherwise noted in this application or otherwise clearly contradicted, all methods described herein can be according to this area skill The understanding of art personnel, is carried out in any suitable order.
All patents, patent application and the bibliography quoted in the application are incorporated by this Shen by reference Please, its incorporated extent is individually recited as reference just as each document.If the application and provided herein is document between In the presence of conflict, content that should be in the application is defined.
This application describes preferred embodiment and embodiment, those skilled in the art are reading the basis of the application On, appropriate change can be carried out to implementation method described herein and embodiment.Therefore, the application includes that law allows model Enclose all equivalent modifications and variations of theme in interior claims to the application.
Specific embodiment：
The present invention is illustrated with specific examples below, but is not limited to these embodiments.Effect reality of the invention Test using indoor biometricses by the way of field test is combined.Unless otherwise instructed, ratio mentioned below is all quality percentage Than.
Following example of formulations is further illustrated to of the invention, but the present invention is not limited solely in present embodiment Preparation compositions.Percentage composition is mass percent in all formulations proportioning.Active compound and agricultural chemicals employed in embodiment are helped Agent is market purchase and obtains, and the model of auxiliary agent is also known in the art to be known.
Embodiment 1：16% SYP-Z048 alkene oxime amine microemulsion
Weigh 8g SYP-Z048s active compound, 8g alkene oxime amine active compounds, 8g 1-METHYLPYRROLIDONEs, 17g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 2：20% SYP-Z048 alkene oxime amine suspending agent
Weigh 15g SYP-Z048s active compound, 5g alkene oxime amines active compound, 8g FS3000 (Phosphate Anionic Surfactants), 1g TXC (sulfonate anionic surfactant), 0.3g xanthans, 1g aluminium-magnesium silicates, 2g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 3：60% SYP-Z048 alkene oxime amine water dispersible granules
Weigh 50g SYP-Z048s active compound, 10g alkene oxime amines active compound, 4g Ufoxane 3A (lignosulfonates), 4g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 4g white carbons, 10g ammonium sulfate, 10g cornstarch, kaolin add To 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 4：22% SYP-Z048 alkene oxime amine aqueous emulsion
Weigh 20g SYP-Z048s active compound, 2g alkene oxime amines active compound, 3.5g SK-5050 (compositions：Polyoxyethylene aryl ether), 4.8g SK-551 (compositions：Styrene phenol polyoxyethylene anionic dispersing agents), the synergist (Silwet of 2gSilwet 806 Composition is organic silicon), 0.18g xanthans, 5g ethylene glycol, 0.3g benzoic acid, 0.5g defoamers (composition be organically-modified silica Alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 5：16% SYP-Z048 alkene oxime amine soluble powder
Weigh 15g SYP-Z048s active compound, 1g alkene oxime amines active compound, 6g alkyl benzene calcium sulfonates, 12g ammonium sulfate, 2g alkylnaphthalenes Sulfonate and anion humectant mixture, 0.3g Sodium Benzoates and cornstarch polishing are to 100g.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 6：21% SYP-Z048 alkene oxime amine microemulsion
Weigh 20g SYP-Z048s active compound, 1g alkene oxime amine active compounds, 7g 1-METHYLPYRROLIDONEs, 18g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 7：31% SYP-Z048 alkene oxime amine suspending agent
Weigh 30g SYP-Z048s active compound, 1g alkene oxime amines active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 8：41% SYP-Z048 alkene oxime amine wettable powder
40g SYP-Z048s active compound, 1g alkene oxime amine active compounds are weighed, 2g neopelexes, 8g white carbons, 8g are wooden Plain sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill powder Broken mixing, obtains wettable powder.
Embodiment 9：65% SYP-Z048 alkene oxime amine water dispersible granules
Weigh 45g SYP-Z048s active compound, 20g alkene oxime amines active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g sulfuric acid Ammonium, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow After crushing, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 10：8.1% SYP-Z048 alkene oxime amine microemulsion
Weigh 8g SYP-Z048s active compound, 0.1g alkene oxime amine active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 11：5% SYP-Z048 alkene oxime amine aqua
Weigh 2.5g SYP-Z048s active compound, 2.5g alkene oxime amine active compounds, 6g phenethyl phenol polyethenoxy ethers condensation product, 0.3g Sodium Benzoate, water complements to 100g.Above-mentioned raw materials are added into mixer to be well mixed, you can obtain aqua.
Embodiment 12：10% SYP-Z048 alkene oxime amine microemulsion
Weigh 2.5g SYP-Z048s active compound, 7.5g alkene oxime amine active compounds, 6g 1-METHYLPYRROLIDONEs, 15g isopropanols, 4g Agriculture breast 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 13：30% SYP-Z048 alkene oxime amine wettable powder
Weigh 5g SYP-Z048s active compound, 25g alkene oxime amine active compounds, 1g neopelexes, 10g white carbons, 10g wood Quality sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill It is pulverized and mixed, obtains wettable powder.
Embodiment 14：55% SYP-Z048 alkene oxime amine water dispersible granules
Weigh 5g SYP-Z048s active compound, 50g alkene oxime amines active compound, 3g Ufoxane 3A (lignosulfonates), 3g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 3g white carbons, 15g ammonium sulfate, 10g cornstarch, kaolin are added to 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 15：80% SYP-Z048 alkene oxime amine water dispersible granules
Weigh 5g SYP-Z048s active compound, 75g alkene oxime amines active compound, the sodium salt of 2g alkyl naphthalene sulfonic acid condensation polymers, 5g ammonium sulfate, 2g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 16：21% SYP-Z048 alkene oxime amine Seed Treatment microcapsule suspending agent
Weigh 1% SYP-Z048 active compound, 20% alkene oxime amine active compound, Ultrazine NA 1%, Sodium Polyacrylate 2%, Polyureas performed polymer 10%, styrene maleic anhydride copolymer 1%, dimethylbenzene 15%, hydrochloric acid 3%, NaOH 0.01%, Xanthans 0.01%, dispersible pigment color paste 3%, polyvinyl alcohol 2%, water complements to 100%.Active ingredient is dissolved in xylene solvent In, obtain homogeneous oil-phase solution；The aqueous solution containing emulsifying dispersant is added thereto to, with being stirred vigorously, is made with solid Body active compound, dimethylbenzene are oil phase, take the aqueous solution containing emulsifying dispersant as the O/W type stable emulsions of water phase.To prepare in advance Urea-formaldehyde prepolymer add emulsion in, using low content hydrochloric acid regulating system pH value, be polymerized under acid catalysed conditions Reaction, is wrapped oil phase substance, forms microcapsule suspending agent.To in this microcapsule suspending agent add thickener, antifreeze, into Film, alert toner, stir, and both obtain Seed Treatment microcapsule suspending agent.
Embodiment 17：62% SYP-Z048 alkene oxime amine Seed Treatment dispersible pulvis
2g SYP-Z048s active compound, 60g alkene oxime amines active compound, NNO 5% are weighed, pigment toner 3%, white carbon 5% is wooden Plain sodium sulfonate 3%, lauryl sodium sulfate 2%, kaolin complements to 100%.According to recipe requirements, active ingredient is disperseed Agent, alert toner, carrier premixing are uniform, then are crushed, and are then well mixed, and Con trolling index is detected at any time, qualified rear discharging, Packing, obtains final product Seed Treatment dispersible pulvis.
Embodiment 18：41% SYP-Z048 alkene oxime amine suspending agent
Weigh 1g SYP-Z048s active compound, 40g alkene oxime amines active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 19：65% SYP-Z048 alkene oxime amine water dispersible granules
Weigh 5g SYP-Z048s active compound, 60g alkene oxime amines active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 20：8.1% SYP-Z048 alkene oxime amine microemulsion
Weigh 0.1g SYP-Z048s active compound, 8g alkene oxime amine active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 21：16% SYP-Z048 azoles amine bacterium ester microemulsion
Weigh 8g SYP-Z048s active compound, 8g azoles amine bacterium ester active compounds, 8g 1-METHYLPYRROLIDONEs, 17g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 22：20% SYP-Z048 azoles amine bacterium ester suspending agent
Weigh 15g SYP-Z048s active compound, 5g azoles amine bacterium esters active compound, 8g FS3000 (Phosphate Anionic Surfactants), 1g TXC (sulfonate anionic surfactant), 0.3g xanthans, 1g aluminium-magnesium silicates, 2g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 23：60% SYP-Z048 azoles amine bacterium ester water dispersible granules
Weigh 50g SYP-Z048s active compound, 10g azoles amine bacterium esters active compound, 4g Ufoxane 3A (lignosulfonates), 4g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 4g white carbons, 10g ammonium sulfate, 10g cornstarch, kaolin add To 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 24：22% SYP-Z048 azoles amine bacterium ester aqueous emulsion
Weigh 20g SYP-Z048s active compound, 2g azoles amine bacterium esters active compound, 3.5g SK-5050 (compositions：Polyoxyethylene aryl ether), 4.8g SK-551 (compositions：Styrene phenol polyoxyethylene anionic dispersing agents), the synergist (Silwet of 2g Silwet 806 Composition is organic silicon), 0.18g xanthans, 5g ethylene glycol, 0.3g benzoic acid, 0.5g defoamers (composition be organically-modified silica Alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 25：16% SYP-Z048 azoles amine bacterium ester soluble powder
Weigh 15g SYP-Z048s active compound, 1g azoles amine bacterium esters active compound, 6g alkyl benzene calcium sulfonates, 12g ammonium sulfate, 2g alkylnaphthalenes Sulfonate and anion humectant mixture, 0.3g Sodium Benzoates and cornstarch polishing are to 100g.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 26：21% SYP-Z048 azoles amine bacterium ester microemulsion
Weigh 20g SYP-Z048s active compound, 1g azoles amine bacterium ester active compounds, 7g 1-METHYLPYRROLIDONEs, 18g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 27：31% SYP-Z048 azoles amine bacterium ester suspending agent
Weigh 30g SYP-Z048s active compound, 1g azoles amine bacterium esters active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 28：41% SYP-Z048 azoles amine bacterium ester wettable powder
40g SYP-Z048s active compound, 1g azoles amine bacterium ester active compounds are weighed, 2g neopelexes, 8g white carbons, 8g are wooden Plain sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill powder Broken mixing, obtains wettable powder.
Embodiment 29：65% SYP-Z048 azoles amine bacterium ester water dispersible granules
Weigh 45g SYP-Z048s active compound, 20g azoles amine bacterium esters active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g sulfuric acid Ammonium, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow After crushing, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 30：8.1% SYP-Z048 azoles amine bacterium ester microemulsion
Weigh 8g SYP-Z048s active compound, 0.1g azoles amine bacterium ester active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 31：5% SYP-Z048 azoles amine bacterium ester aqua
Weigh 2.5g SYP-Z048s active compound, 2.5g azoles amine bacterium ester active compounds, 6g phenethyl phenol polyethenoxy ethers condensation product, 0.3g Sodium Benzoate, water complements to 100g.Above-mentioned raw materials are added into mixer to be well mixed, you can obtain aqua.
Embodiment 32：10% SYP-Z048 azoles amine bacterium ester microemulsion
Weigh 2.5g SYP-Z048s active compound, 7.5g azoles amine bacterium ester active compounds, 6g 1-METHYLPYRROLIDONEs, 15g isopropanols, 4g Agriculture breast 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 33：30% SYP-Z048 azoles amine bacterium ester wettable powder
Weigh 5g SYP-Z048s active compound, 25g azoles amine bacterium ester active compounds, 1g neopelexes, 10g white carbons, 10g wood Quality sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill It is pulverized and mixed, obtains wettable powder.
Embodiment 34：55% SYP-Z048 azoles amine bacterium ester water dispersible granules
Weigh 5g SYP-Z048s active compound, 50g azoles amine bacterium esters active compound, 3g Ufoxane 3A (lignosulfonates), 3g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 3g white carbons, 15g ammonium sulfate, 10g cornstarch, kaolin are added to 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 35：80% SYP-Z048 azoles amine bacterium ester water dispersible granules
Weigh 5g SYP-Z048s active compound, 75g azoles amine bacterium esters active compound, the sodium salt of 2g alkyl naphthalene sulfonic acid condensation polymers, 5g ammonium sulfate, 2g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 36：21% SYP-Z048 azoles amine bacterium ester Seed Treatment microcapsule suspending agent
Weigh 1% SYP-Z048 active compound, 20% azoles amine bacterium ester active compound, Ultrazine NA 1%, Sodium Polyacrylate 2%, Polyureas performed polymer 10%, styrene maleic anhydride copolymer 1%, dimethylbenzene 15%, hydrochloric acid 3%, NaOH 0.01%, Xanthans 0.01%, dispersible pigment color paste 3%, polyvinyl alcohol 2%, water complements to 100%.Active ingredient is dissolved in xylene solvent In, obtain homogeneous oil-phase solution；The aqueous solution containing emulsifying dispersant is added thereto to, with being stirred vigorously, is made with solid Body active compound, dimethylbenzene are oil phase, take the aqueous solution containing emulsifying dispersant as the O/W type stable emulsions of water phase.To prepare in advance Urea-formaldehyde prepolymer add emulsion in, using low content hydrochloric acid regulating system pH value, be polymerized under acid catalysed conditions Reaction, is wrapped oil phase substance, forms microcapsule suspending agent.To in this microcapsule suspending agent add thickener, antifreeze, into Film, alert toner, stir, and both obtain Seed Treatment microcapsule suspending agent.
Embodiment 37：62% SYP-Z048 azoles amine bacterium ester Seed Treatment dispersible pulvis
2g SYP-Z048s active compound, 60g azoles amine bacterium esters active compound, NNO 5% are weighed, pigment toner 3%, white carbon 5% is wooden Plain sodium sulfonate 3%, lauryl sodium sulfate 2%, kaolin complements to 100%.According to recipe requirements, active ingredient is disperseed Agent, alert toner, carrier premixing are uniform, then are crushed, and are then well mixed, and Con trolling index is detected at any time, qualified rear discharging, Packing, obtains final product Seed Treatment dispersible pulvis.
Embodiment 38：41% SYP-Z048 azoles amine bacterium ester suspending agent
Weigh 1g SYP-Z048s active compound, 40g azoles amine bacterium esters active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 39：65% SYP-Z048 azoles amine bacterium ester water dispersible granules
Weigh 5g SYP-Z048s active compound, 60g azoles amine bacterium esters active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 40：8.1% SYP-Z048 azoles amine bacterium ester microemulsion
Weigh 0.1g SYP-Z048s active compound, 8g azoles amine bacterium ester active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 41：16% SYP-Z048 kresoxim-methyl microemulsion
Weigh 8g SYP-Z048s active compound, 8g kresoxim-methyl active compounds, 8g 1-METHYLPYRROLIDONEs, 17g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 42：20% SYP-Z048 kresoxim-methyl suspending agent
Weigh 15g SYP-Z048s active compound, 5g kresoxim-methyls active compound, 8g FS3000 (Phosphate Anionic Surfactants), 1g TXC (sulfonate anionic surfactant), 0.3g xanthans, 1g aluminium-magnesium silicates, 2g ethylene glycol, 0.2g BIT (1,2- benzos Isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added into height to cut Cut and shear in mulser 10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 43：60% SYP-Z048 water dispersion granules agent of Kresoxim
Weigh 50g SYP-Z048s active compound, 10g kresoxim-methyls active compound, 4g Ufoxane 3A (lignosulfonates), 4g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 4g white carbons, 10g ammonium sulfate, 10g cornstarch, kaolin are added to 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 44：22% SYP-Z048 kresoxim-methyl aqueous emulsion
Weigh 20g SYP-Z048s active compound, 2g kresoxim-methyls active compound, 3.5g SK-5050 (compositions：Polyoxyethylene aryl ether), 4.8g SK-551 (compositions：Styrene phenol polyoxyethylene anionic dispersing agents), the synergist (Silwet of 2gSilwet 806 Composition is organic silicon), 0.18g xanthans, 5g ethylene glycol, 0.3g benzoic acid, 0.5g defoamers (composition be organically-modified silica Alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 45：16% SYP-Z048 kresoxim-methyl soluble powder
Weigh 15g SYP-Z048s active compound, 1g kresoxim-methyls active compound, 6g alkyl benzene calcium sulfonates, 12g ammonium sulfate, 2g alkylnaphthalene sulphurs Hydrochlorate and anion humectant mixture, 0.3g Sodium Benzoates and cornstarch polishing are to 100g.It is well mixed, through air-flow crushing Afterwards, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 46：21% SYP-Z048 kresoxim-methyl microemulsion
Weigh 20g SYP-Z048s active compound, 1g kresoxim-methyl active compounds, 7g 1-METHYLPYRROLIDONEs, 18g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 47：31% SYP-Z048 kresoxim-methyl suspending agent
Weigh 30g SYP-Z048s active compound, 1g kresoxim-methyls active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzos Isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added into height to cut Cut and shear in mulser 10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 48：41% SYP-Z048 kresoxim-methyl wettable powder
Weigh 40g SYP-Z048s active compound, 1g kresoxim-methyl active compounds, 2g neopelexes, 8g white carbons, 8g lignin Sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, crushed into airslide disintegrating mill Mixing, obtains wettable powder.
Embodiment 49：65% SYP-Z048 water dispersion granules agent of Kresoxim
Weigh 45g SYP-Z048s active compound, 20g kresoxim-methyls active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 50：8.1% SYP-Z048 kresoxim-methyl microemulsion
Weigh 8g SYP-Z048s active compound, 0.1g kresoxim-methyl active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 51：5% SYP-Z048 kresoxim-methyl aqua
Weigh 2.5g SYP-Z048s active compound, 2.5g kresoxim-methyl active compounds, 6g phenethyl phenol polyethenoxy ethers condensation product, 0.3g benzene Sodium formate, water complements to 100g.Above-mentioned raw materials are added into mixer to be well mixed, you can obtain aqua.
Embodiment 52：10% SYP-Z048 kresoxim-methyl microemulsion
Weigh 2.5g SYP-Z048s active compound, 7.5g kresoxim-methyl active compounds, 6g 1-METHYLPYRROLIDONEs, 15g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 53：30% SYP-Z048 kresoxim-methyl wettable powder
5g SYP-Z048s active compound, 25g kresoxim-methyl active compounds are weighed, 1g neopelexes, 10g white carbons, 10g are wooden Plain sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill powder Broken mixing, obtains wettable powder.
Embodiment 54：55% SYP-Z048 water dispersion granules agent of Kresoxim
Weigh 5g SYP-Z048s active compound, 50g kresoxim-methyls active compound, 3g Ufoxane 3A (lignosulfonates), 3g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 3g white carbons, 15g ammonium sulfate, 10g cornstarch, kaolin are added to 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 55：80% SYP-Z048 water dispersion granules agent of Kresoxim
Weigh 5g SYP-Z048s active compound, 75g kresoxim-methyls active compound, the sodium salt of 2g alkyl naphthalene sulfonic acid condensation polymers, 5g ammonium sulfate, 2g Alkylnaphthalene sulfonate and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow crushing Afterwards, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 56：21% SYP-Z048 kresoxim-methyl Seed Treatment microcapsule suspending agent
Weigh 1% SYP-Z048 active compound, 20% kresoxim-methyl active compound, Ultrazine NA1%, Sodium Polyacrylate 2%, polyureas Performed polymer 10%, styrene maleic anhydride copolymer 1%, dimethylbenzene 15%, hydrochloric acid 3%, NaOH 0.01%, xanthan Glue 0.01%, dispersible pigment color paste 3%, polyvinyl alcohol 2%, water complements to 100%.Active ingredient is dissolved in xylene solvent, is obtained To homogeneous oil-phase solution；The aqueous solution containing emulsifying dispersant is added thereto to, with being stirred vigorously, is made former with solid Medicine, dimethylbenzene are oil phase, take the aqueous solution containing emulsifying dispersant as the O/W type stable emulsions of water phase.The urine that will be prepared in advance Element-formaldehyde pre-polymer is added in emulsion, using low content hydrochloric acid regulating system pH value, polymerization occurs under acid catalysed conditions anti- Should, oil phase substance is wrapped, form microcapsule suspending agent.To addition thickener, antifreeze, film forming in this microcapsule suspending agent Agent, alert toner, stir, and both obtain Seed Treatment microcapsule suspending agent.
Embodiment 57：62% SYP-Z048 kresoxim-methyl Seed Treatment dispersible pulvis
Weigh 2g SYP-Z048s active compound, 60g kresoxim-methyls active compound, NNO 5%, pigment toner 3%, white carbon 5%, lignin Sodium sulfonate 3%, lauryl sodium sulfate 2%, kaolin complements to 100%.According to recipe requirements, by active ingredient dispersant, Alert toner, carrier premixing are uniform, then are crushed, and are then well mixed, and Con trolling index is detected at any time, qualified rear discharging, point Dress, obtains final product Seed Treatment dispersible pulvis.
Embodiment 58：41% SYP-Z048 kresoxim-methyl suspending agent
Weigh 1g SYP-Z048s active compound, 40g kresoxim-methyls active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzos Isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added into height to cut Cut and shear in mulser 10min, then after being sanded with sand mill, obtain suspending agent.
Embodiment 59：65% SYP-Z048 water dispersion granules agent of Kresoxim
Weigh 5g SYP-Z048s active compound, 60g kresoxim-methyls active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate, 4g Alkylnaphthalene sulfonate and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow crushing Afterwards, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 60：8.1% SYP-Z048 kresoxim-methyl microemulsion
Weigh 0.1g SYP-Z048s active compound, 8g kresoxim-methyl active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 61：16% SYP-Z048 SYP-3375 microemulsion
Weigh 8g SYP-Z048s active compound, 8g SYP-3375 active compounds, 8g 1-METHYLPYRROLIDONEs, 17g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 62：20% SYP-Z048 SYP-3375 suspending agent
Weigh 15g SYP-Z048s active compound, 5g SYP-3375s active compound, 8g FS3000 (Phosphate Anionic Surfactants), 1g TXC (sulfonate anionic surfactant), 0.3g xanthans, 1g aluminium-magnesium silicates, 2g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to Shear 10min in high-shear emulsion machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 63：60% SYP-Z048 SYP-3375 water dispersible granules
Weigh 50g SYP-Z048s active compound, 10g SYP-3375s active compound, 4g Ufoxane 3A (lignosulfonates), 4g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 4g white carbons, 10g ammonium sulfate, 10g cornstarch, kaolin add To 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 64：22% SYP-Z048 SYP-3375 aqueous emulsion
Weigh 20g SYP-Z048s active compound, 2g SYP-3375s active compound, 3.5g SK-5050 (compositions：Polyoxyethylene aryl ether), 4.8g SK-551 (compositions：Styrene phenol polyoxyethylene anionic dispersing agents), the synergist (Silwet of 2gSilwet 806 Composition is organic silicon), 0.18g xanthans, 5g ethylene glycol, 0.3g benzoic acid, 0.5g defoamers (composition be organically-modified silica Alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 65：16% SYP-Z048 SYP-3375 soluble powder
Weigh 15g SYP-Z048s active compound, 1g SYP-3375s active compound, 6g alkyl benzene calcium sulfonates, 12g ammonium sulfate, 2g alkylnaphthalenes Sulfonate and anion humectant mixture, 0.3g Sodium Benzoates and cornstarch polishing are to 100g.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 66：21% SYP-Z048 SYP-3375 microemulsion
Weigh 20g SYP-Z048s active compound, 1g SYP-3375 active compounds, 7g 1-METHYLPYRROLIDONEs, 18g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 67：31% SYP-Z048 SYP-3375 suspending agent
Weigh 30g SYP-Z048s active compound, 1g SYP-3375s active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 68：41% SYP-Z048 SYP-3375 wettable powder
40g SYP-Z048s active compound, 1g SYP-3375 active compounds are weighed, 2g neopelexes, 8g white carbons, 8g are wooden Plain sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill powder Broken mixing, obtains wettable powder.
Embodiment 69：65% SYP-Z048 SYP-3375 water dispersible granules
Weigh 45g SYP-Z048s active compound, 20g SYP-3375s active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g sulfuric acid Ammonium, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow After crushing, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 70：8.1% SYP-Z048 SYP-3375 microemulsion
Weigh 8g SYP-Z048s active compound, 0.1g SYP-3375 active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 71：5% SYP-Z048 SYP-3375 aqua
Weigh 2.5g SYP-Z048s active compound, 2.5g SYP-3375 active compounds, 6g phenethyl phenol polyethenoxy ethers condensation product, 0.3g Sodium Benzoate, water complements to 100g.Above-mentioned raw materials are added into mixer to be well mixed, you can obtain aqua.
Embodiment 72：10% SYP-Z048 SYP-3375 microemulsion
Weigh 2.5g SYP-Z048s active compound, 7.5g SYP-3375 active compounds, 6g 1-METHYLPYRROLIDONEs, 15g isopropanols, 4g Agriculture breast 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniformly Oil phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained Preferable microemulsion.
Embodiment 73：30% SYP-Z048 SYP-3375 wettable powder
Weigh 5g SYP-Z048s active compound, 25g SYP-3375 active compounds, 1g neopelexes, 10g white carbons, 10g wood Quality sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill It is pulverized and mixed, obtains wettable powder.
Embodiment 74：55% SYP-Z048 SYP-3375 water dispersible granules
Weigh 5g SYP-Z048s active compound, 50g SYP-3375s active compound, 3g Ufoxane 3A (lignosulfonates), 3g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 3g white carbons, 15g ammonium sulfate, 10g cornstarch, kaolin are added to 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 75：80% SYP-Z048 SYP-3375 water dispersible granules
Weigh 5g SYP-Z048s active compound, 75g SYP-3375s active compound, the sodium salt of 2g alkyl naphthalene sulfonic acid condensation polymers, 5g ammonium sulfate, 2g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 76：21% SYP-Z048 SYP-3375 Seed Treatment microcapsule suspending agent
1% SYP-Z048 active compound, 20% SYP-3375 active compound, Ultrazine NA1% are weighed, Sodium Polyacrylate 2% gathers Urea performed polymer 10%, styrene maleic anhydride copolymer 1%, dimethylbenzene 15%, hydrochloric acid 3%, NaOH 0.01% is yellow Virgin rubber 0.01%, dispersible pigment color paste 3%, polyvinyl alcohol 2%, water complements to 100%.Active ingredient is dissolved in xylene solvent, Obtain homogeneous oil-phase solution；The aqueous solution containing emulsifying dispersant is added thereto to, with being stirred vigorously, is made former with solid Medicine, dimethylbenzene are oil phase, take the aqueous solution containing emulsifying dispersant as the O/W type stable emulsions of water phase.The urine that will be prepared in advance Element-formaldehyde pre-polymer is added in emulsion, using low content hydrochloric acid regulating system pH value, polymerization occurs under acid catalysed conditions anti- Should, oil phase substance is wrapped, form microcapsule suspending agent.To addition thickener, antifreeze, film forming in this microcapsule suspending agent Agent, alert toner, stir, and both obtain Seed Treatment microcapsule suspending agent.
Embodiment 77：62% SYP-Z048 SYP-3375 Seed Treatment dispersible pulvis
2g SYP-Z048s active compound, 60g SYP-3375s active compound, NNO 5% are weighed, pigment toner 3%, white carbon 5% is wooden Plain sodium sulfonate 3%, lauryl sodium sulfate 2%, kaolin complements to 100%.According to recipe requirements, active ingredient is disperseed Agent, alert toner, carrier premixing are uniform, then are crushed, and are then well mixed, and Con trolling index is detected at any time, qualified rear discharging, Packing, obtains final product Seed Treatment dispersible pulvis.
Embodiment 78：41% SYP-Z048 SYP-3375 suspending agent
Weigh 1g SYP-Z048s active compound, 40g SYP-3375s active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 79：65% SYP-Z048 SYP-3375 water dispersible granules
Weigh 5g SYP-Z048s active compound, 60g SYP-3375s active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 80：8.1% SYP-Z048 SYP-3375 microemulsion
Weigh 0.1g SYP-Z048s active compound, 8g SYP-3375 active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 81：16% SYP-Z048 ZJ0712 microemulsion
Weigh 8g SYP-Z048s active compound, 8g ZJ0712 active compounds, 8g 1-METHYLPYRROLIDONEs, 17g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 82：20% SYP-Z048 ZJ0712 suspending agent
Weigh 15g SYP-Z048s active compound, 5g ZJ0712s active compound, 8g FS3000 (Phosphate Anionic Surfactants), 1g TXC (sulfonate anionic surfactant), 0.3g xanthans, 1g aluminium-magnesium silicates, 2g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 83：60% SYP-Z048 ZJ0712 water dispersible granules
Weigh 50g SYP-Z048s active compound, 10g ZJ0712s active compound, 4g Ufoxane 3A (lignosulfonates), 4g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 4g white carbons, 10g ammonium sulfate, 10g cornstarch, kaolin add To 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 84：22% SYP-Z048 ZJ0712 aqueous emulsion
Weigh 20g SYP-Z048s active compound, 2g ZJ0712s active compound, 3.5g SK-5050 (compositions：Polyoxyethylene aryl ether), 4.8g SK-551 (compositions：Styrene phenol polyoxyethylene anionic dispersing agents), the synergist (Silwet of 2gSilwet 806 Composition is organic silicon), 0.18g xanthans, 5g ethylene glycol, 0.3g benzoic acid, 0.5g defoamers (composition be organically-modified silica Alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 85：16% SYP-Z048 ZJ0712 soluble powder
Weigh 15g SYP-Z048s active compound, 1g ZJ0712s active compound, 6g alkyl benzene calcium sulfonates, 12g ammonium sulfate, 2g alkylnaphthalenes Sulfonate and anion humectant mixture, 0.3g Sodium Benzoates and cornstarch polishing are to 100g.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 86：21% SYP-Z048 ZJ0712 microemulsion
Weigh 20g SYP-Z048s active compound, 1g ZJ0712 active compounds, 7g 1-METHYLPYRROLIDONEs, 18g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 87：31% SYP-Z048 ZJ0712 suspending agent
Weigh 30g SYP-Z048s active compound, 1g ZJ0712s active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 88：41% SYP-Z048 ZJ0712 wettable powder
40g SYP-Z048s active compound, 1g ZJ0712 active compounds are weighed, 2g neopelexes, 8g white carbons, 8g are wooden Plain sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill powder Broken mixing, obtains wettable powder.
Embodiment 89：65% SYP-Z048 ZJ0712 water dispersible granules
Weigh 45g SYP-Z048s active compound, 20g ZJ0712s active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g sulfuric acid Ammonium, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow After crushing, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 90：8.1% SYP-Z048 ZJ0712 microemulsion
Weigh 8g SYP-Z048s active compound, 0.1g ZJ0712 active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 91：5% SYP-Z048 ZJ0712 aqua
Weigh 2.5g SYP-Z048s active compound, 2.5g ZJ0712 active compounds, 6g phenethyl phenol polyethenoxy ethers condensation product, 0.3g Sodium Benzoate, water complements to 100g.Above-mentioned raw materials are added into mixer to be well mixed, you can obtain aqua.
Embodiment 92：10% SYP-Z048 ZJ0712 microemulsion
Weigh 2.5g SYP-Z048s active compound, 7.5g ZJ0712 active compounds, 6g 1-METHYLPYRROLIDONEs, 15g isopropanols, 4g Agriculture breast 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 93：30% SYP-Z048 ZJ0712 wettable powder
Weigh 5g SYP-Z048s active compound, 25g ZJ0712 active compounds, 1g neopelexes, 10g white carbons, 10g wood Quality sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill It is pulverized and mixed, obtains wettable powder.
Embodiment 94：55% SYP-Z048 ZJ0712 water dispersible granules
Weigh 5g SYP-Z048s active compound, 50g ZJ0712s active compound, 3g Ufoxane 3A (lignosulfonates), 3g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 3g white carbons, 15g ammonium sulfate, 10g cornstarch, kaolin are added to 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 95：80% SYP-Z048 ZJ0712 water dispersible granules
Weigh 5g SYP-Z048s active compound, 75g ZJ0712s active compound, the sodium salt of 2g alkyl naphthalene sulfonic acid condensation polymers, 5g ammonium sulfate, 2g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 96：21% SYP-Z048 ZJ0712 Seed Treatment microcapsule suspending agent
1% SYP-Z048 active compound, 20% ZJ0712 active compound, Ultrazine NA1% are weighed, Sodium Polyacrylate 2% gathers Urea performed polymer 10%, styrene maleic anhydride copolymer 1%, dimethylbenzene 15%, hydrochloric acid 3%, NaOH 0.01% is yellow Virgin rubber 0.01%, dispersible pigment color paste 3%, polyvinyl alcohol 2%, water complements to 100%.Active ingredient is dissolved in xylene solvent, Obtain homogeneous oil-phase solution；The aqueous solution containing emulsifying dispersant is added thereto to, with being stirred vigorously, is made former with solid Medicine, dimethylbenzene are oil phase, take the aqueous solution containing emulsifying dispersant as the O/W type stable emulsions of water phase.The urine that will be prepared in advance Element-formaldehyde pre-polymer is added in emulsion, using low content hydrochloric acid regulating system pH value, polymerization occurs under acid catalysed conditions anti- Should, oil phase substance is wrapped, form microcapsule suspending agent.To addition thickener, antifreeze, film forming in this microcapsule suspending agent Agent, alert toner, stir, and both obtain Seed Treatment microcapsule suspending agent.
Embodiment 97：62% SYP-Z048 ZJ0712 Seed Treatment dispersible pulvis
2g SYP-Z048s active compound, 60g ZJ0712s active compound, NNO 5% are weighed, pigment toner 3%, white carbon 5% is wooden Plain sodium sulfonate 3%, lauryl sodium sulfate 2%, kaolin complements to 100%.According to recipe requirements, active ingredient is disperseed Agent, alert toner, carrier premixing are uniform, then are crushed, and are then well mixed, and Con trolling index is detected at any time, qualified rear discharging, Packing, obtains final product Seed Treatment dispersible pulvis.
Embodiment 98：41% SYP-Z048 ZJ0712 suspending agent
Weigh 1g SYP-Z048s active compound, 40g ZJ0712s active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 99：65% SYP-Z048 ZJ0712 water dispersible granules
Weigh 5g SYP-Z048s active compound, 60g ZJ0712s active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 100：8.1% SYP-Z048 ZJ0712 microemulsion
Weigh 0.1g SYP-Z048s active compound, 8g ZJ0712 active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 101：16% SYP-Z048 SSF 126 microemulsion
Weigh 8g SYP-Z048s active compound, 8g SSF 126 active compounds, 8g 1-METHYLPYRROLIDONEs, 17g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 102：20% SYP-Z048 SSF 126 suspending agent
Weigh 15g SYP-Z048s active compound, 5g SSF 126s active compound, 8g FS3000 (Phosphate Anionic Surfactants), 1g TXC (sulfonate anionic surfactant), 0.3g xanthans, 1g aluminium-magnesium silicates, 2g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 103：60% SYP-Z048 SSF 126 water dispersible granules
Weigh 50g SYP-Z048s active compound, 10g SSF 126s active compound, 4g Ufoxane 3A (lignosulfonates), 4g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 4g white carbons, 10g ammonium sulfate, 10g cornstarch, kaolin add To 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 104：22% SYP-Z048 SSF 126 aqueous emulsion
Weigh 20g SYP-Z048s active compound, 2g SSF 126s active compound, 3.5g SK-5050 (compositions：Polyoxyethylene aryl ether), 4.8g SK-551 (compositions：Styrene phenol polyoxyethylene anionic dispersing agents), the synergist (Silwet of 2gSilwet 806 Composition is organic silicon), 0.18g xanthans, 5g ethylene glycol, 0.3g benzoic acid, 0.5g defoamers (composition be organically-modified silica Alkane), deionized water adds to 100g.Above-mentioned raw materials are added to after shearing 10min in high-shear emulsion machine, obtain aqueous emulsion.
Embodiment 105：16% SYP-Z048 SSF 126 soluble powder
Weigh 15g SYP-Z048s active compound, 1g SSF 126s active compound, 6g alkyl benzene calcium sulfonates, 12g ammonium sulfate, 2g alkylnaphthalenes Sulfonate and anion humectant mixture, 0.3g Sodium Benzoates and cornstarch polishing are to 100g.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 106：21% SYP-Z048 SSF 126 microemulsion
Weigh 20g SYP-Z048s active compound, 1g SSF 126 active compounds, 7g 1-METHYLPYRROLIDONEs, 18g isopropanols, 4g agriculture breasts 600#, 6g agriculture breast 1601#, add water and complement to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase； Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, physical and chemical performance is obtained preferable Microemulsion.
Embodiment 107：31% SYP-Z048 SSF 126 suspending agent
Weigh 30g SYP-Z048s active compound, 1g SSF 126s active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- benzene And isothiazoline -3- ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to height Shear 10min in emulsification pretreatment machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 108：41% SYP-Z048 SSF 126 wettable powder
40g SYP-Z048s active compound, 1g SSF 126 active compounds are weighed, 2g neopelexes, 8g white carbons, 8g are wooden Plain sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill powder Broken mixing, obtains wettable powder.
Embodiment 109：65% SYP-Z048 SSF 126 water dispersible granules
Weigh 45g SYP-Z048s active compound, 20g SSF 126s active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g sulfuric acid Ammonium, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow After crushing, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 110：8.1% SYP-Z048 SSF 126 microemulsion
Weigh 8g SYP-Z048s active compound, 0.1g SSF 126 active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 111：5% SYP-Z048 SSF 126 aqua
Weigh 2.5g SYP-Z048s active compound, 2.5g SSF 126 active compounds, 6g phenethyl phenol polyethenoxy ethers condensation product, 0.3g Sodium Benzoate, water complements to 100g.Above-mentioned raw materials are added into mixer to be well mixed, you can obtain aqua.
Embodiment 112：10% SYP-Z048 SSF 126 microemulsion
Weigh 2.5g SYP-Z048s active compound, 7.5g SSF 126 active compounds, 6g 1-METHYLPYRROLIDONEs, 15g isopropanols, 4g Agriculture breast 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
Embodiment 113：30% SYP-Z048 SSF 126 wettable powder
Weigh 5g SYP-Z048s active compound, 25g SSF 126 active compounds, 1g neopelexes, 10g white carbons, 10g wood Quality sodium sulfonate, precipitated calcium carbonate complements to 100g.Above-mentioned raw materials are mixed, is crushed through Roughpulverizer, into airslide disintegrating mill It is pulverized and mixed, obtains wettable powder.
Embodiment 114：55% SYP-Z048 SSF 126 water dispersible granules
Weigh 5g SYP-Z048s active compound, 50g SSF 126s active compound, 3g Ufoxane 3A (lignosulfonates), 3g EFW (alkylnaphthalene sulfonate and anion humectant mixture), 3g white carbons, 15g ammonium sulfate, 10g cornstarch, kaolin are added to 100g.It is well mixed, through air-flow crushing after, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 115：80% SYP-Z048 SSF 126 water dispersible granules
Weigh 5g SYP-Z048s active compound, 75g SSF 126s active compound, the sodium salt of 2g alkyl naphthalene sulfonic acid condensation polymers, 5g ammonium sulfate, 2g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 116：21% SYP-Z048 SSF 126 Seed Treatment microcapsule suspending agent
1% SYP-Z048 active compound, 20% SSF 126 active compound, Ultrazine NA1% are weighed, Sodium Polyacrylate 2% gathers Urea performed polymer 10%, styrene maleic anhydride copolymer 1%, dimethylbenzene 15%, hydrochloric acid 3%, NaOH 0.01% is yellow Virgin rubber 0.01%, dispersible pigment color paste 3%, polyvinyl alcohol 2%, water complements to 100%.Active ingredient is dissolved in xylene solvent, Obtain homogeneous oil-phase solution；The aqueous solution containing emulsifying dispersant is added thereto to, with being stirred vigorously, is made former with solid Medicine, dimethylbenzene are oil phase, take the aqueous solution containing emulsifying dispersant as the O/W type stable emulsions of water phase.The urine that will be prepared in advance Element-formaldehyde pre-polymer is added in emulsion, using low content hydrochloric acid regulating system pH value, polymerization occurs under acid catalysed conditions anti- Should, oil phase substance is wrapped, form microcapsule suspending agent.To addition thickener, antifreeze, film forming in this microcapsule suspending agent Agent, alert toner, stir, and both obtain Seed Treatment microcapsule suspending agent.
Embodiment 117：62% SYP-Z048 SSF 126 Seed Treatment dispersible pulvis
2g SYP-Z048s active compound, 60g SSF 126s active compound, NNO 5% are weighed, pigment toner 3%, white carbon 5% is wooden Plain sodium sulfonate 3%, lauryl sodium sulfate 2%, kaolin complements to 100%.According to recipe requirements, active ingredient is disperseed Agent, alert toner, carrier premixing are uniform, then are crushed, and are then well mixed, and Con trolling index is detected at any time, qualified rear discharging, Packing, obtains final product Seed Treatment dispersible pulvis.
Embodiment 118：41% SYP-Z048 SSF 126 suspending agent
Weigh 1g SYP-Z048s active compound, 40g SSF 126s active compound, 8g FS3000 (Phosphate Anionic Surfactants), 2g TXC (sulfonate anionic surfactant), 0.2g xanthans, 1g aluminium-magnesium silicates, 1g ethylene glycol, 0.2g BIT (1,2- Benzisothiazole-3-ketone), the organically-modified silica alkane defoamers of 0.3g, deionized water adds to 100g.Above-mentioned raw materials are added to Shear 10min in high-shear emulsion machine, then after being sanded with sand mill, obtain suspending agent.
Embodiment 119：65% SYP-Z048 SSF 126 water dispersible granules
Weigh 5g SYP-Z048s active compound, 60g SSF 126s active compound, the sodium salt of 4g alkyl naphthalene sulfonic acid condensation polymers, 4g ammonium sulfate, 4g alkylnaphthalene sulfonates and anion humectant mixture, 1g potassium sorbates and 10g cornstarch.It is well mixed, through air-flow powder After broken, granulated in comminutor, then dry, screening obtains final product granular product.
Embodiment 120：8.1% SYP-Z048 SSF 126 microemulsion
Weigh 0.1g SYP-Z048s active compound, 8g SSF 126 active compounds, 5g 1-METHYLPYRROLIDONEs, 10g isopropanols, 4g agricultures Newborn 600#, 6g agriculture breast 1601#, adds water and complements to 100g.Active compound, solvent, emulsifying agent are added together, make to be dissolved into uniform oil Phase；Water-soluble component and water are mixed to prepare water phase；Under high velocity agitation, it is oil phase is mixed with water, be obtained physical and chemical performance compared with Good microemulsion.
The measurement result of the indoor virulence of EXPERIMENTAL EXAMPLE 1.：
Inventor by SYP-Z048 and alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl or SYP-3375 mixture, to wheat scab Germ (Fusarium graminearum), gray mold of cucumber germ (the pathogen of Botrytis cinerea), leaf muld of tomato germ (yellow branch spore bacterium), tomato early epidemic Germ (sporulation) carries out co-toxicity test, and specific test situation and result are as follows：
Using mycelial growth rate method.Under sterile conditions, the card punch with a diameter of 5mm is cultivating the germ bacterium of 5d The edge that falls is beaten and takes bacteria cake, is placed in a series of PDA culture medium containing mass concentration gradient medicaments, and with adding the PDA of sterilized water Used as control, then be positioned over culture medium in 25 DEG C of insulating boxs for each treatment by each 3 repetition for the treatment of, is tied after culture 7d Fruit is investigated.
The colony diameter for often processing is measured using crossing method during investigation respectively, bacteriostasis rate is then calculated.
Bacteriostasis rate (%)=[(control colony diameter-original bacteria cake diameter)-(treatment colony diameter-original bacteria cake diameter)]/ [(control colony diameter-original bacteria cake diameter)] × 100
According to bacteriostasis rate, virulence regression equation and EC are obtained50Value, calculates each by Sun-Johnson toxicity indexes calculating method Match the co-toxicity coefficient of mixture.
SYP-Z048 and alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl or SYP-3375 mixture, to wheat scab germ (standing grain Paddy sickle-like bacteria), gray mold of cucumber germ (the pathogen of Botrytis cinerea), leaf muld of tomato germ (yellow branch spore bacterium), early blight of tomato germ The result that (sporulation) carries out co-toxicity test is shown in table 1- tables 4.
The SYP-Z048 of table 1. is with alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl, SYP-3375 composition to wheat scab germ (Fusarium graminearum) interior joint toxicity measuring result
The result of table 1 shows, different ratio shows synergistic effect, wherein SYP-Z048 and alkene oxime amine, azoles amine bacterium ester, Kresoxim-methyl, SYP-3375 proportioning are 20:1-1:It is better when 20.Illustrate SYP-Z048 and alkene oxime amine, azoles amine bacterium ester, Kresoxim-methyl, SYP-3375 mixture prevents and treats wheat scab has reasonability and feasibility.
The SYP-Z048 of table 2. is with alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl, SYP-3375 composition to gray mold of cucumber germ (the pathogen of Botrytis cinerea) interior joint toxicity measuring result
The result of table 2 shows, different ratio shows synergistic effect, wherein SYP-Z048 and alkene oxime amine, azoles amine bacterium ester, Kresoxim-methyl, SYP-3375 proportioning are 20:1-1:It is better when 20.Illustrate SYP-Z048 and alkene oxime amine, azoles amine bacterium ester, Kresoxim-methyl, SYP-3375 mixture preventing and treating gray mold of cucumber have reasonability and feasibility.
The SYP-Z048 of table 3. is with alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl, SYP-3375 composition to leaf muld of tomato germ (yellow branch spore bacterium) interior joint toxicity measuring result
The result of table 3 shows, different ratio shows synergistic effect, wherein SYP-Z048 and alkene oxime amine, azoles amine bacterium ester, Kresoxim-methyl, SYP-3375 proportioning are 20:1-1:It is better when 20.Illustrate SYP-Z048 and alkene oxime amine, azoles amine bacterium ester, Kresoxim-methyl, SYP-3375 mixture prevents and treats leaf muld of tomato has reasonability and feasibility.
The SYP-Z048 of table 4. is with alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl, SYP-3375 composition to early blight of tomato germ (sporulation) interior joint toxicity measuring result
The result of table 4 shows, different ratio shows synergistic effect, wherein SYP-Z048 and alkene oxime amine, azoles amine bacterium ester, Kresoxim-methyl, SYP-3375 proportioning are 20:1-1:It is better when 20.Illustrate SYP-Z048 and alkene oxime amine, azoles amine bacterium ester, Kresoxim-methyl, SYP-3375 mixture prevents and treats early blight of tomato has reasonability and feasibility.
By table 1- tables 4 as can be seen that the different ratio of SYP-Z048 and methoxy acrylic bactericide shows Synergistic effect.SYP-Z048 is with alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl, SYP-3375 mixture for preventing and treating wheat scab disease Bacterium (Fusarium graminearum), gray mold of cucumber germ (the pathogen of Botrytis cinerea), leaf muld of tomato germ (yellow branch spore bacterium), early blight of tomato Various pest and disease damages such as germ (sporulation) are respectively provided with reasonability and feasibility.
The field test results of EXPERIMENTAL EXAMPLE 2.：
The present embodiment detected in experimental plot the preparation of different embodiments for prevent and treat wheat scab, gray mold of cucumber, The result of leaf muld of tomato and early blight of tomato.When applying, per hectare consumption can reach bactericidal composition in embodiment 200-400g active components.
2.1 different embodiments prevent and treat wheat scab result of the test：
2.1.1 test material and method：
Experimental plot is located at Liyang Li cities and towns, and experimental field preferably, cultivation management is consistent, Pass Test for water and fertilizer condition It is required that.For studying thing for wheat, kind is to raise spoke wheat No. 4, plot area 60m2.Experiment sets 22 treatment altogether, containing clear water control, Often process 3 repetitions, cell random alignment.
25% SYP-Z048 missible oil, 20% alkene oxime amine missible oil and 20% azoles amine bacterium ester suspending agent are by Shenyang Chemical Engineering Inst There is provided, 50% water dispersion granules agent of Kresoxim and 20% SYP-3375 suspending agent buy gained by market.
2.1.2 investigation method, time and number of times：
In wheat flowering initial stage (about 20%) medication, interval sprays a medicine, continuous dispenser 2 times for 6 days.Every 667 square metres 30L is watered, cauline leaf spraying is carried out, blank spray clear water, other water and fertilizer managements are consistent with surrounding crop field with insect pest preventing and controlling.
Incidence is managed everywhere in (after secondary medicine 25 days) investigation investigation after wheat scab stable disease.Treatment region is diagonal 5 points of samplings of line, every 50 fringes of investigation, record the incidence of disease；According to site of pathological change and hazard rating situation, disease index, meter are calculated Calculate preventive effect.
2.1.3 drug effect computational methods:
Severity Scaling standard is as follows：
0 grade：Disease-free spot；
1 grade：Sick fringe area accounts for less than the 1/4 of full fringe area；
2 grades:Sick fringe area accounts for the 1/4~1/2 of full fringe area；
3 grades：Sick fringe area accounts for the 1/2~3/4 of full fringe area；
4 grades：Sick fringe area accounts for more than the 3/4 of full fringe area；
Diseased plant rate (%)=diseased plant number/investigation strain number × 100
2.1.4 to the other influences of crop
A situation arises and wheat growth situation for observation field diseases, observes the influence to Growth of Wheat, plant height, leaf color Deng whether investigation crop has poisoning, and records poisoning type and extent of injury.
2.1.5 result of the test and analysis
The different embodiments of table 5. prevent and treat wheat scab result of the test
As shown in Table 5, alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl and SYP-3375 single dose will to the preventive effect of wheat scab A little higher than SYP-Z048, will be apparently higher than the preventive effect of single dose to the preventive effect of wheat scab by each embodiment for compounding.Compounding The prevention effect of the bactericidal composition of mixture is generally higher by more than 10% than the prevention effect of any one separate constituent. Illustrate that SYP-Z048 has substantially with alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl and SYP-3375 compounding to preventing and treating wheat scab Synergistic effect.Estimated according to field, in the range of test dose, plant growth is normal, and each treatment agent does not occur to small The poisoning phenomenon of wheat, illustrates that it is safe to wheat.
2.2 different embodiment preventing and treating gray mold of cucumber result of the tests：
2.2.1 test material and method：
Experimental plot is located at Fujian Province Putian City Huangshi town, and physical features is flat, and irrigation and drainage are convenient.It is cucumber for examination vegetables, kind is "Jinyou No.41", plot area 20m2.Experiment sets 22 treatment altogether, containing clear water control, often processes 3 repetitions, cell random alignment.
25% SYP-Z048 missible oil, 20% alkene oxime amine missible oil and 20% azoles amine bacterium ester suspending agent are by Shenyang Chemical Engineering Inst There is provided, 50% water dispersion granules agent of Kresoxim and 20% SYP-3375 suspending agent buy gained by market.
2.2.2 investigation method, time and number of times：
First meeting gray mold of cucumber spot is started medication, and a medicine was sprayed every 7 days, is sprayed 2 times altogether.State of an illness radix is investigated before dispenser,
5 days after second dispenser, investigate the state of an illness within 10 days.Random per cell to take 5 points of investigation, every is investigated 2 plants, every plant of investigation Whole fruits, a situation arises to investigate and be classified in record sampling point gray mold in whole cucumber fruits.
Disease fruit classification uses following standard (in units of fruit)：
0 grade：Disease-free spot；
1 grade：Residual flower morbidity；
3 grades：Fall ill in areola portion；
5 grades：Scab length accounts for less than the 10% of fruit；
7 grades：Scab length accounts for 11-the 25% of fruit；
9 grades：Scab length accounts for more than the 26% of fruit；
2.2.3 drug effect computational methods:
In formula:Disease refers to before CK0-blank district dispenser；Disease refers to after CK1-blank district dispenser；
Disease refers to before PT0-chemicals treatment district dispenser；Disease refers to after PT1-chemicals treatment district dispenser.
2.2.4 to the other influences of crop
Whether observation crop has poisoning to produce, and should also record other beneficial effects to crop.
2.2.5 result of the test and analysis
The different embodiment preventing and treating gray mold of cucumber result of the tests of table 6.
As shown in Table 6, SYP-Z048 single dose is higher than alkene oxime amine, azoles amine bacterium ester, ether bacterium to the preventive effect of gray mold of cucumber Ester and SYP-3375 single dose, are all significantly improved by preventive effect after compounding compared to single dose.Compound the Bactericidal composite of mixture The prevention effect of thing is generally higher by more than 20% than the prevention effect of any one separate constituent.Illustrate SYP-Z048 and alkene oxime Bacterium amine, azoles amine bacterium ester, kresoxim-methyl and SYP-3375 compounding have synergistic effect to gray mold of cucumber.Field is estimated, test dose In the range of, plant growth is normal.
2.3 different embodiments prevent and treat leaf muld of tomato result of the test：
2.3.1 test material and method：
Experimental plot is located at Fujian Province Putian City Huangshi town, and physical features is flat, and irrigation and drainage are convenient.It is tomato for examination vegetables, kind is Kai Rui, plot area 20m2.Experiment sets 22 treatment altogether, containing clear water control, often processes 3 repetitions, cell random alignment.
25% SYP-Z048 missible oil, 20% alkene oxime amine missible oil and 20% azoles amine bacterium ester suspending agent are by Shenyang Chemical Engineering Inst There is provided, 50% water dispersion granules agent of Kresoxim and 20% SYP-3375 suspending agent buy gained by market.
2.3.2 investigation method, time and number of times：
Leaf muld of tomato spot early period of origination first time medication, second dispenser after 7 days, altogether dispenser 2 times.Disease is investigated before dispenser Feelings radix, 7 days after first time dispenser, 7 days investigation state of an illness after second dispenser.It is random per cell to take 5 points of investigation, every investigation 2 Strain, every plant point of upper, middle and lower part takes a representational compound leaf, accounts for whole with every vanelets lesion area on compound leaf The classification of individual vanelets area percentage, a situation arises to investigate and be classified in record sampling point leaf mold on whole tomato leafs.
0 grade：Disease-free spot；
1 grade：Lesion area accounts for less than the 5% of blade area；
3 grades：Lesion area accounts for the 6%-10% of blade area；
5 grades：Lesion area accounts for the 11%-25% of blade area；
7 grades：Lesion area accounts for the 26%-50% of blade area；
9 grades：The percentage that lesion area accounts for blade area is more than 50%.
2.3.3 drug effect computational methods:
In formula:CK0Disease refers to before the dispenser of-blank district；CK1Disease refers to after the dispenser of-blank district；
PT0Disease refers to before the dispenser of-chemicals treatment district；PT1Disease refers to after the dispenser of-chemicals treatment district.
2.3.4 to the other influences of crop
Whether observation crop has poisoning to produce, and should also record other beneficial effects to crop.
2.3.5 result of the test and analysis
The different embodiments of table 7. prevent and treat leaf muld of tomato result of the test
As can be seen from Table 7, SYP-Z048 single dose is prevented and treated the effect of leaf muld of tomato and is better than alkene oxime amine single dose, with azoles The preventive effect difference of amine bacterium ester, kresoxim-methyl and SYP-3375 single dose is not obvious.By the preventive effect of each embodiment after compounding compared to list Agent is obviously improved, and the prevention effect for compounding the bactericidal composition of mixture will than the prevention effect of any one separate constituent Generally it is higher by more than 20%.Illustrate SYP-Z048 with alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl and SYP-3375 compounding to tomato leaf There is mildew notable synergistic to act on.Field is estimated, and each treatment does not occur to tomato poisoning phenomenon.
2.4 different embodiments prevent and treat early blight of tomato result of the test：
2.4.1 test material and method：
Experimental plot is located at Fujian Province Putian City Guo Huan towns, and physical features is flat, and irrigation and drainage are convenient.It is tomato for examination vegetables, kind is Zhejiang powder 202, plot area 20m2.Experiment sets 22 treatment altogether, containing clear water control, often processes 3 repetitions, cell random alignment.
25% SYP-Z048 missible oil, 20% alkene oxime amine missible oil and 20% azoles amine bacterium ester suspending agent are by Shenyang Chemical Engineering Inst There is provided, 50% water dispersion granules agent of Kresoxim and 20% SYP-3375 suspending agent buy gained by market.
2.4.2 investigation method, time and number of times：
First time dispenser before early blight of tomato, second dispenser after 7 days, altogether dispenser 2 times.7 days and 14 after second dispenser Its investigation state of an illness.Random per cell to take 5 points of investigation, every is looked into two plants, and 10 leaves are investigated in every plant point of upper, middle and lower, with per a piece of Lesion area on leaf accounts for the percentage of whole leaf area to be classified.
Stage division (in units of blade)：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for less than the 5% of blade area；
3 grades：Lesion area accounts for the 6%-10% of blade area；
5 grades：Lesion area accounts for the 11%-25% of blade area；
7 grades：Lesion area accounts for the 26%-50% of blade area；
9 grades：The percentage that lesion area accounts for blade area is more than 50%.
2.4.3 drug effect computational methods:
If not investigating state of an illness radix before dispenser, prevention effect is calculated by formula (3)：
In formula：CK0--- disease index before blank district dispenser；CK1--- disease index after blank district dispenser；
PT0--- disease index before chemicals treatment district dispenser；PT1--- disease index after chemicals treatment district dispenser.
2.4.4 to the other influences of crop
Whether observation crop has poisoning to produce, and should also record other beneficial effects to crop.
2.4.5 result of the test and analysis
The embodiment of table 8. prevents and treats early blight of tomato result of the test
SYP-Z048 single dose wants a little higher than alkene oxime amine, azoles amine bacterium ester, ether bacterium to the preventive effect of early blight of tomato as shown in Table 8 The preventive effect of ester and SYP-3375 single dose.Have bright compared to single dose to the preventive effect of early blight of tomato by each embodiment after compounding Aobvious to improve, the prevention effect for compounding the bactericidal composition of mixture is generally higher than the prevention effect of any one separate constituent Go out more than 10%.Illustrate that SYP-Z048 has with alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl and SYP-3375 compounding to early blight of tomato There is obvious synergistic effect.Field is estimated, and in the range of test dose, plant growth is normal, and it is right that each treatment agent does not occur The poisoning phenomenon of tomato.
SYP-Z048 is can be seen that by the field test effect of table 5- tables 8 to be compounded with methoxy acrylic bactericide Afterwards, prevention effect phase of the preparation of each embodiment to wheat scab, gray mold of cucumber, leaf muld of tomato and early blight of tomato Than being all significantly improved in single dose.It is right that this explanation SYP-Z048 is compounded with alkene oxime amine, azoles amine bacterium ester, kresoxim-methyl and SYP-3375 Wheat scab, gray mold of cucumber, leaf muld of tomato and early blight of tomato have obvious synergistic effect.
In sum, the composition containing SYP-Z048 Yu methoxy acrylic bactericide of the invention, to cucumber ash Various fungies such as mildew, leaf muld of tomato, wheat scab, early blight of tomato have preferable prevention effect, and it is to target Crop safety.Toxicity measurement result shows, SYP-Z048：Methoxy acrylic bactericide is 40:1—1:40 scopes It is interior to there is notable synergistic to act on wheat scab, gray mold of cucumber, leaf muld of tomato and early blight of tomato germ, wherein optimal The compound proportion of choosing is 20:1—1:20.
Complex preparation not only increases preventive effect, and expands fungicidal spectrum, widens and uses scope, reduces the medication of single dose Amount, reduces cost, delays drug-fast generation, and multiple diseases are played a part of with a medicine is simultaneous to be controlled, and improves productivity effect.Institute So that the invention of this complex preparation improves tool and is of great significance with popularization to disease control and crop yield.

Claims (12)

1. a kind of bactericidal composition, it is characterised in that：The composition contains active component SYP-Z048 and methoxy acrylic acid Esters bactericide.
2. bactericidal composition according to claim 1, the methoxy acrylic bactericide is selected from alkene oxime amine, azoles Any one in amine bacterium ester, kresoxim-methyl, ZJ0712, SSF 126 or SYP-3375, is preferably selected from alkene oxime amine, azoles amine bacterium Any one in ester, kresoxim-methyl or SYP-3375.
3. bactericidal composition according to claim 1, it is characterised in that the SYP-Z048 and methoxy acrylic The ratio of weight and number of bactericide is 1:80-80:1, preferably 1:40-40:1, more preferably 1:20-20:1.
4. bactericidal composition according to claim 1, it is characterised in that the SYP-Z048 and methoxy acrylic The weight summation of bactericide accounts for the 1%-80% of the bactericidal composition gross weight, preferably 5%-65%.
5. bactericidal composition according to claim 1, it is characterised in that the bactericidal composition also includes filler, preferably Described filler is selected from kaolin, diatomite, white carbon, attapulgite, bentonite, zeolite powder, resin, clay powder, wooden chaff, gelatinization One or more in starch, paraffin, methylcellulose, carboxymethylcellulose calcium and carboxyethyl cellulose.
6. bactericidal composition according to claim 1, it is characterised in that the bactericidal composition also includes auxiliary agent, preferably The auxiliary agent is selected from agriculture breast 1601#, alkylaryl sulfonates, lignosulfonates, lactic casein, mineral oil, gelatin, polyvinyl alcohol In one or more.
7. the bactericidal composition according to any one in claim 1-6, it is characterised in that the bactericidal composition is water Suspending agent, dispersible oil-suspending agent, aqueous emulsion, microcapsule formulations, microemulsion, wettable powder, soluble powder, water-dispersible grain Agent, Seed Treatment dispersant, suspension seed-coating agent or Seed Treatment microcapsule suspending agent, preferably described bactericidal composition are aqueous suspension Agent, dispersible oil-suspending agent, aqueous emulsion, water dispersible granules, suspension seed-coating agent.
8. the purposes for controlling plant diseases of the bactericidal composition in a kind of claim 1-7 described in any one.
9. purposes according to claim 8, it is characterised in that the plant disease be by oomycetes, sac fungus, basidiomycetes and The plant disease that Fungi Imperfecti causes, it is preferable that the plant disease includes graw mold of tomato, gray mold of cucumber, tomato early epidemic Disease, leaf spot of peanut, powdery mildew of cucumber, cucumber anthracnose, leaf muld of tomato, alternaria leaf spot of apple, wheat scab, cotton Droop, banana Panama disease, banana blight, bakanae disease of rice, watermelon blight, citrus anthracnose.
10. a kind of method of controlling plant diseases, it is characterised in that by sterilized group described in any one in claim 1-7 Compound is applied to plant and planting region with controlling plant diseases.
11. methods according to claim 10, it is characterised in that the group of the active component of the bactericidal composition will be included Point be made preparation administration, or will include the active component of the bactericidal composition component bucket it is mixed after apply.
A kind of 12. methods for preparing the bactericidal composition as described in any one in claim 1-7, it is characterised in that by institute State SYP-Z048, the methoxy acrylic bactericide and optional described filler or auxiliary agent mixing.
CN201510897871.2A 2015-12-08 2015-12-08 Bactericidal composition containing SYP-Z048 Pending CN106852332A (en)

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CN112823630A (en) * 2019-11-21 2021-05-21 沈阳中化农药化工研发有限公司 Seed treatment agent for sterilization
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Application publication date: 20170616