CN106414417B - 制备二氢异噁唑衍生物的方法 - Google Patents

制备二氢异噁唑衍生物的方法 Download PDF

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Publication number
CN106414417B
CN106414417B CN201580027637.2A CN201580027637A CN106414417B CN 106414417 B CN106414417 B CN 106414417B CN 201580027637 A CN201580027637 A CN 201580027637A CN 106414417 B CN106414417 B CN 106414417B
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China
Prior art keywords
formula
chlorine
preparing
compound
mixture
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CN201580027637.2A
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English (en)
Chinese (zh)
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CN106414417A (zh
Inventor
G·霍姆伯格
M·J·福特
A·许格尔
土屋知己
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Bayer CropScience AG
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Bayer CropScience AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201580027637.2A 2014-05-28 2015-05-27 制备二氢异噁唑衍生物的方法 Active CN106414417B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14170155.7 2014-05-28
EP14170155 2014-05-28
PCT/EP2015/061623 WO2015181189A1 (en) 2014-05-28 2015-05-27 Process for preparing dihydroisoxazole derivatives

Publications (2)

Publication Number Publication Date
CN106414417A CN106414417A (zh) 2017-02-15
CN106414417B true CN106414417B (zh) 2019-04-16

Family

ID=50828731

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580027637.2A Active CN106414417B (zh) 2014-05-28 2015-05-27 制备二氢异噁唑衍生物的方法

Country Status (12)

Country Link
US (1) US9796690B2 (enExample)
EP (1) EP3148976B1 (enExample)
JP (1) JP6533798B2 (enExample)
KR (1) KR102337028B1 (enExample)
CN (1) CN106414417B (enExample)
BR (1) BR112016027824B1 (enExample)
DK (1) DK3148976T3 (enExample)
ES (1) ES2730048T3 (enExample)
IL (1) IL248568B (enExample)
MX (1) MX382631B (enExample)
TW (1) TWI665192B (enExample)
WO (1) WO2015181189A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3265439T3 (da) * 2015-03-05 2019-06-11 Bayer Cropscience Ag Fremgangsmåde til fremstilling af 3-chlor-2-vinylphenylsulfonater
BR112019011605B1 (pt) * 2016-12-05 2023-03-07 Bayer Cropscience Aktiengesellschaft Método para preparação de 2-vinilfenil sulfonato 3-substituído e seu intermediário
CN113891882B (zh) * 2019-06-14 2024-11-26 组合化学工业株式会社 二氢异噁唑的制造方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101970432A (zh) * 2008-01-25 2011-02-09 杜邦公司 杀真菌杂环化合物
CN102791133A (zh) * 2010-01-07 2012-11-21 纳幕尔杜邦公司 杀真菌杂环化合物
WO2013098229A2 (de) * 2011-12-27 2013-07-04 Bayer Intellectual Property Gmbh Heteroarylpiperidin und -piperazinderivate als fungizide

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0350237A3 (en) 1988-07-08 1990-08-29 Schering Agrochemicals Limited Triazole insecticides
DE4331448A1 (de) 1993-09-16 1995-03-23 Hoechst Schering Agrevo Gmbh Substituierte Isoxazoline, Verfahren zu deren Herstellung, diese enthaltende Mittel und deren Verwendung als Safener
EP1878730A1 (en) 2006-07-12 2008-01-16 Bayer Schering Pharma Aktiengesellschaft Substituted isoxazolines, pharmaceutical compositions containing the same, methods of preparing the same, and uses of the same
WO2008013622A2 (en) * 2006-07-27 2008-01-31 E. I. Du Pont De Nemours And Company Fungicidal azocyclic amides
CN101925598B (zh) * 2008-01-25 2014-03-05 杜邦公司 杀真菌酰胺
WO2010057160A1 (en) 2008-11-17 2010-05-20 Enzon Pharmaceuticals, Inc. Releasable fusogenic lipids for nucleic acids delivery systems
EP2820015A1 (en) * 2012-03-02 2015-01-07 Syngenta Participations AG Microbiocidal pyrazole derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101970432A (zh) * 2008-01-25 2011-02-09 杜邦公司 杀真菌杂环化合物
CN102791133A (zh) * 2010-01-07 2012-11-21 纳幕尔杜邦公司 杀真菌杂环化合物
WO2013098229A2 (de) * 2011-12-27 2013-07-04 Bayer Intellectual Property Gmbh Heteroarylpiperidin und -piperazinderivate als fungizide

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Stepwise Intramolecular Cycloaddition of Nitrile Oxide Equivalents Derived from the Lewis Acid-promoted Reaction of 1 -Nitroalkadienes and Allylic Stannanes;Hidemitsu Uno et al.;《J.Chem.Soc.Perkin Trans I》;19890101;289-295 *

Also Published As

Publication number Publication date
IL248568A0 (en) 2016-12-29
KR20170012331A (ko) 2017-02-02
IL248568B (en) 2019-03-31
TWI665192B (zh) 2019-07-11
MX2016015623A (es) 2017-02-27
ES2730048T3 (es) 2019-11-07
BR112016027824B1 (pt) 2021-03-23
EP3148976A1 (en) 2017-04-05
US20170247345A1 (en) 2017-08-31
JP6533798B2 (ja) 2019-06-19
MX382631B (es) 2025-03-13
TW201625567A (zh) 2016-07-16
KR102337028B1 (ko) 2021-12-07
DK3148976T3 (da) 2019-05-27
EP3148976B1 (en) 2019-03-13
CN106414417A (zh) 2017-02-15
WO2015181189A1 (en) 2015-12-03
US9796690B2 (en) 2017-10-24
JP2017517513A (ja) 2017-06-29

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