CN106389895B - Chinese medicine composition of relieving sore-throat and its preparation method and application is moisturized in nourishiing yin to clear away the lung-heat - Google Patents
Chinese medicine composition of relieving sore-throat and its preparation method and application is moisturized in nourishiing yin to clear away the lung-heat Download PDFInfo
- Publication number
- CN106389895B CN106389895B CN201510439367.8A CN201510439367A CN106389895B CN 106389895 B CN106389895 B CN 106389895B CN 201510439367 A CN201510439367 A CN 201510439367A CN 106389895 B CN106389895 B CN 106389895B
- Authority
- CN
- China
- Prior art keywords
- parts
- lung
- heat
- throat
- chinese medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to the Chinese medicine compositions and its preparation method and application that relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat.The active constituent of the Chinese medicine composition is prepared by following raw material: 44-52 parts of great burdock achene, 15-20 parts of reed root, 10-15 parts of Chinese olive, 8-16 parts of glutinous rehmannia, Radix Ophiopogonis 8-16 part, 8-16 parts of radix scutellariae, 5-13 parts of cortex moutan, 11-19 parts of radix paeoniae rubra, 5-13 parts of campanulaceae, 11-29 parts of radix scrophulariae, 8-16 parts of dendrobium nobile, 8-16 parts of chrysanthemum, 8-16 parts of peppermint, 11-16 parts of cordate houttuynia, 10-15 parts of the root bark of white mulberry, 2-10 parts of Radix Glycyrrhizae.The effect of Chinese medicine composition that relieving sore-throat is moisturized in the nourishiing yin to clear away the lung-heat has nourishing Yin and promoting production of body fluid, and QI invigorating promoting the circulation of qi, promoting the dispersing function of the lung relieving sore-throat, removing heat from lung and relieving asthma is clearing heat and detoxicating, dispelling wind and heat from the body, according to clinical verification, will not generate pharmacological dependence, also have the advantages that good effect, safety and stability.And preparation process is simple, safety and sanitation.Using massage cream made of Chinese medicine composition of the present invention and matrix or carrier, it is mild to skin it is non-stimulated, have no toxic side effect, have the effect of comprehensive clearing lung-heat.
Description
Technical field
The present invention relates to Chinese medicine external product field, more particularly to a kind of nourishiing yin to clear away the lung-heat moisturize relieving sore-throat Chinese medicine composition and
Preparation method and application.
Background technique
The breathing of lung governing qi department, main a surname send out drop respectful and cure mainly section towards hundred arteries and veins；Therefore lung is with the breathing for administering adjusting lung and entirely
The effect of the gas, blood, water of body.But lungs are clear empty and delicate, and happiness profit is not dry, suctions it is then full, that exhales is then empty, for the canopy of internal organs,
The institute of hundred arteries and veins is towards meeting；Again due to lung position highest, and it is the dirty of clear void, communicates with the outside world, clear light solemn silence does not allow fine mustard, intolerant to heresy
Gas is invaded, thus temperature it is evil outer invade, internal injury or other viscera lesions, all disease and cough, asthma, hemoptysis, aphonia, lung can occur in lung
The illnesss such as consumptive disease, consumptive lung disease.And throat is one of human body vitals, accounts for 40% with different degrees of sphagitis patient.With warp
The high speed development of Ji, the living environment severe exacerbation of the mankind, while rhythm of life are accelerated, and the diet of people, living habit and come
From the various pressure in life and work, the body of people is made to be chronically at the state of over fatigue, easy perverse trend invades body, and yin-fluid is lost
Consumption, yin sun not processed, water fire not processed, flaring up of deficient fire follow and are above disturbed throat, throat illness, such as burst abscess of throat occur, simultaneously
Pulmonary disease disease incidence is also increasing.
Currently, western medicine can only temporarily control the state of an illness, taking excessive anti-inflammatory drug, antibiotic or sulfa drugs be will lead to
Yin-Yang disequilibrium, immunologic hypofunction, resistance decline, and then keep Relapse rate refractory.Moreover, treating lung at present
With the mostly oral drugs of throat illness, drug can be slackened the efficacy of a drug later by oral administration the effects of digestive juice in gastrointestinal disturbances road,
Stimulation can be generated to gastrointestinal disturbances road simultaneously, influence digestive function.On the contrary, topical drug have many advantages, such as it is easy to use, safe.
Summary of the invention
Based on this, it is necessary to it is undesirable for common oral drugs curative effect and to intestines and stomach exist stimulation and effect subtract
The disadvantages of weak, provides a kind of nourishiing yin to clear away the lung-heat and moisturizes Chinese medicine composition of relieving sore-throat and its preparation method and application.
An object of the present invention is to provide the Chinese medicine composition that relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat.
Specific technical solution is as follows:
The Chinese medicine composition of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, and the active constituent of the Chinese medicine composition is by following weight
Part raw material is prepared: 44-52 parts of great burdock achene, 15-20 parts of reed root, 10-15 parts of Chinese olive, 8-16 parts of glutinous rehmannia, Radix Ophiopogonis 8-16 part, yellow
8-16 parts of a kind of reed mentioned in ancient books, 5-13 parts of cortex moutan, 11-19 parts of radix paeoniae rubra, 5-13 parts of campanulaceae, 11-29 parts of radix scrophulariae, 8-16 parts of dendrobium nobile, chrysanthemum 8-16
Part, 8-16 parts of peppermint, 11-16 parts of cordate houttuynia, 10-15 parts of the root bark of white mulberry, 2-10 parts of Radix Glycyrrhizae.
In one of the embodiments, the active constituent of the Chinese medicine composition be prepared by following raw material and
At: 46 parts of great burdock achene, 16 parts of reed root, 12 parts of Chinese olive, 13 parts of glutinous rehmannia, 11 parts of Radix Ophiopogonis, 11 parts of radix scutellariae, 8 parts of cortex moutan, radix paeoniae rubra 13
Part, 8 parts of campanulaceae, 13 parts of radix scrophulariae, 13 parts of dendrobium nobile, 11 parts of chrysanthemum, 11 parts of peppermint, 13 parts of cordate houttuynia, 11 parts of the root bark of white mulberry, 6 parts of Radix Glycyrrhizae.
The Chinese medicine composition of relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat provided by the present invention, according to the theory of Chinese medicine " monarch ",
Add dry great burdock achene, Chinese olive, reed root, campanulaceae, glutinous rehmannia, Radix Ophiopogonis, radix scrophulariae be monarch drug in a prescription, have promoting the dispersing function of the lung relieving sore-throat, nourishing Yin and promoting production of body fluid, heat-clearing solution
The effect of malicious；Add chrysanthemum, peppermint, dendrobium nobile fish, raw meat grass, the root bark of white mulberry be ministerial drug, have dispelling wind and heat from the body, removing heat from lung and relieving asthma, promoting the circulation of qi it
Effect；Adding radix scutellariae, cortex moutan, radix paeoniae rubra is adjutant, has the effect of cool blood, promoting blood circulation, stagnation resolvation；Addition Radix Glycyrrhizae is to make medicine, is had
QI invigorating, coordinating the drug actions of a prescription reduce the effect of toxicity.
The pharmacological action difference of each ingredient is as follows:
Great burdock achene: dispelling wind and heat from the body, promoting the dispersing function of the lung promoting eruption, relieving sore-throat of detoxifying.For anemopyretic cold, coughing with a lot of sputum, morbilli, rubeola, pharynx
Larynx swelling and pain, mumps, carbuncle sore tumefacting virus.
Chinese olive: clearing heat and detoxicating, relieving sore-throat is promoted the production of body fluid.For abscess of throat, phlegm of coughing is glutinous, dysphoria and thirsty.
Reed root: clearing heat-fire promotes the production of body fluid to quench thirst, relieving restlessness, preventing or arresting vomiting, diuresis.For pyreticosis and polydipsia, cough with lung heat, lung carbuncle pyemesis.
Glutinous rehmannia: hot cool blood, nourishing Yin and promoting production of body fluid.For thermal man's ying blood, febrile virulent maculae, hematemesis and epistaxis, consumption of YIN caused by febrile disease, tongue is deep red to be tired of
Yearningly, Tianjin hinder constipation, fever due to yin deficiency, hectic fever due to yin labor heat, Heat Diabetes.
Cortex moutan: clearing heat and cooling blood, activating microcirculation and removing stasis medicinal.For thermal man's ying blood, febrile virulent maculae, hematemesis and epistaxis, night fever abating at dawn is lossless
Hectic fever due to yin.
Radix Ophiopogonis: nourishing Yin and promoting production of body fluid, moistening lung and clearing away the heart-fire.For dryness of the lung dry cough, cough for deficiency of Yin consumptive disease, larynx numbness pharyngalgia, injury thirst, interior heat disappears
Yearningly, vexed insomnia, dry constipation of intestines.
Radix scutellariae: heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention.For damp-warm syndrome, summer-heat and damp, chest tightness and emesis, damp and hot feeling of fullness is rushed down
Dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus.
Radix paeoniae rubra: clearing heat and cooling blood, removing blood stasis and acesodyne.Enter ying blood, febrile virulent maculae, hematemesis and epistaxis, red eye, swell pain, the liver depression side of body for heat
Tong , abdominal mass and abdominal pain, carbuncle swells sore.
Campanulaceae: promoting the dispersing function of the lung, relieving sore-throat, eliminating the phlegm, apocenosis.For coughing with a lot of sputum, chest distress, pharyngalgia hoarse voice, lung carbuncle pyemesis.
Radix scrophulariae: clearing heat and cooling blood, nourishing yin and lessening fire, detoxicating and resolving a mass.For thermal man's ying blood, febrile virulent maculae, consumption of YIN caused by febrile disease, tongue is deep red to be tired of
Yearningly, Tianjin hinder constipation, hectic fever due to yin labor is coughed, hot eyes, pharyngalgia, diphtheria, scrofula, carbuncle sore tumefacting virus.
Dendrobium nobile: stomach promotes the production of body fluid, nourishing Yin and clearing heat.Hurt for pyreticosis saliva, dry polydipsia, deficiency of stomach-Yin, deficiency of food is retched, after being ill abnormal heat
It does not move back, fire excess from yin deficiency, hectic fever due to yin labor heat, mesh is secretly unknown, muscles and bones impotence.
Chrysanthemum: relieve heat heat-clearing, calming the liver and improving eyesight are clearing heat and detoxicating.For anemopyretic cold, headache and dizziness, red eye, swell pain, eyes dusk
Flower, sore and toxic.
Peppermint: dispelling wind and heat from the body, head clearing, relieving sore-throat, promoting eruption, soothing the liver promoting the circulation of qi.For anemopyretic cold, wind-warm syndrome from the beginning of, headache,
Hot eyes, sore throat, aphtha, rubeola, morbilli, Breast bilges frowsty.
Cordate houttuynia: it is pungent, it is slightly cold.It is clearing heat and detoxicating, the carbuncle that disappears apocenosis.It spits for pulmonary abscess, phlegm heat panting cough, too fat to move sore.
The root bark of white mulberry: removing heat from lung and relieving asthma, inducing diuresis for removing edema.For dyspnea and cough due to lung-heat, edema swelling oliguria, appearance skin edema.
Radix Glycyrrhizae: invigorating the spleen and benefiting qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, burnout is weary
Power, shortness of breath and palpitation, coughing with a lot of sputum, carbuncle sore tumefacting virus alleviate drug toxicity, strong.
It is a further object of the present invention to provide the preparation methods that the Chinese medicine composition of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat.
Specific technical solution is as follows:
The preparation method of the Chinese medicine composition of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, comprising the following steps: the raw material is weighed,
Water that 3-10 times of the raw material weight is measured is added or ethanol solution that mass fraction is 10-70% extracts 1-2 time, filter or
It is centrifuged, obtains the Chinese medicine composition after concentrating filter liquor；The method of the extraction be decoct extraction method or reflux extraction or
Ultrasonic extraction or permeating extraction.
In one of the embodiments, the following steps are included: weighing the raw material, 6 times of raw material weight amounts are added
The ethanol solution ultrasonic extraction that mass fraction is 50%, filtering, filter residue continue use 6 times of the raw material weight mass fractions measured for
10% ethanol solution ultrasonic extraction, filtering, merging filtrate is concentrated into medicinal material: the weight ratio of concentrate is 1:0.6 to get arriving
The Chinese medicine composition of relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat.
It is a further object of the present invention to provide a kind of nourishiing yin to clear away the lung-heat to moisturize the Chinese medicine composition of relieving sore-throat in preparation nourishiing yin to clear away the lung-heat
Moisturize the application in the topical drug of relieving sore-throat.
Specific technical solution is as follows:
A kind of nourishiing yin to clear away the lung-heat moisturizes the Chinese medicine composition of relieving sore-throat in the topical drug that relieving sore-throat is moisturized in preparation nourishiing yin to clear away the lung-heat
Using.
It is a further object of the present invention to provide the massage creams that relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat.
Specific technical solution is as follows:
The massage cream of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, and the massage cream is moisturized in relieving sore-throat by above-mentioned nourishiing yin to clear away the lung-heat
Drug composition and massage cream are often prepared with matrix or carrier；The carrier includes water, moisturizer, emulsifier, excipient, screening
Lid agent, emollients, conditioner, suspending agent, chelating agent, preservative and fragrance.
Weight of the Chinese medicine composition of relieving sore-throat in the massage cream is moisturized in the nourishiing yin to clear away the lung-heat in one of the embodiments,
Amount percentage is 10.0-30.0%；Relative density of the Chinese medicine composition at 55 DEG C -65 DEG C is 1.05-1.25.
The massage cream is prepared by the raw material of following weight percent in one of the embodiments: 15.0-
23.0% Chinese medicine composition, 43.0-46.0% water, 3.5-5.5% emulsifier, 2.5-4.5% excipient, 11.5-
13.5% emollients, 0.05-0.09% conditioner, 11.0-13.0% moisturizer, 0.4-0.6% suspending agent, 0.1-0.2% chela
Mixture, 0.4-0.8% covering agent, 0-1.0% preservative, 0-0.3% essence.
The massage cream is prepared by the raw material of following weight percent in one of the embodiments: 20% institute
State Chinese medicine composition, 46.00% water, 4.3% emulsifier, 3.3% excipient, 10.5% emollients, 0.07% conditioner, 14%
Moisturizer, 0.43% suspending agent, 0.1% chelating agent, 0.6% covering agent, 0.6% preservative, 0.1% essence.
The massage cream is prepared by the raw material of following weight percent in one of the embodiments: 20.0%
The Chinese medicine composition, 1.2% stereth -2,1.5% stereth -21,3.3% cetostearyl alcohol, 4.0% carbonic acid
Dibutyl ester, 1.6% stearine, 5.0% isopropyl myristate, 1.5% caprylic/capric triglyceride, 2.0% poly- two
Methylsiloxane, 0.05% bisabolol, 46.00% water, 8.0% butanediol, 2.0% glycerol, 0.23% xanthan gum, 0.2%
Mosanom, 0.1%EDTA disodium, 1.0% glycine betaine, 0.6% titanium dioxide, 0.02% tetrahydro piperine, 1.0%1,3 the third two
Alcohol, 0.6% Phenoxyethanol, 0.1% essence.
The Chinese medicine composition of relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat provided by the present invention, uses pure Chinese medicine for raw material, according to " the monarch and his subjects
Assistant make " tcm theory compatibility form, have nourishing Yin and promoting production of body fluid, QI invigorating promoting the circulation of qi, promoting the dispersing function of the lung relieving sore-throat, removing heat from lung and relieving asthma is clearing heat and detoxicating, evacuation
The effect of wind-heat, will not generate pharmacological dependence according to clinical verification, also have the advantages that good effect, safety and stability.
The preparation method of the Chinese medicine composition of relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat provided by the present invention, has simple process, peace
The advantage of full health.
It is provided by the present invention to moisturize the Chinese medicine composition of relieving sore-throat with above-mentioned nourishiing yin to clear away the lung-heat and massage cream often uses matrix or load
External massage cream made of body preparation, it is mild to skin it is non-stimulated, have no toxic side effect, nourishing Yin and promoting production of body fluid, promoting the dispersing function of the lung relieving sore-throat, purging the lung of pathogenic fire is flat
Asthma, it is clearing heat and detoxicating, reach comprehensive clearing lung-heat effect.Further, since above-mentioned nourishiing yin to clear away the lung-heat is moisturized used in the Chinese medicine composition of relieving sore-throat
Raw material is pure Chinese medicine, antibiotic and hormone is free of, so pharmacological dependence will not be generated.
Specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
The Chinese medicine composition of relieving sore-throat is moisturized in 1 nourishiing yin to clear away the lung-heat of embodiment
The Chinese medicine composition of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, and the active constituent of the Chinese medicine composition is by following parts by weight
Raw material is prepared: 44 parts of great burdock achene, 15 parts of reed root, and 10 parts of Chinese olive, 8 parts of glutinous rehmannia, 8 parts of Radix Ophiopogonis, 8 parts of radix scutellariae, 5 parts of cortex moutan,
11 parts of radix paeoniae rubra, 5 parts of campanulaceae, 11 parts of radix scrophulariae, 8 parts of dendrobium nobile, 8 parts of chrysanthemum, 8 parts of peppermint, 11 parts of cordate houttuynia, 10 parts of the root bark of white mulberry, Radix Glycyrrhizae 2
Part.
Nourishiing yin to clear away the lung-heat moisturize the Chinese medicine composition of relieving sore-throat the preparation method comprises the following steps:
The raw material for weighing above-mentioned parts by weight, is sufficiently mixed, and crushes, sets in ultrasonic extraction tank, is added 6 times of above-mentioned raw materials weight
The ethanol solution that the mass fraction of amount is 70%, ultrasonic extraction 30min are filtered (400 mesh), and filter residue continues using raw material weight
The ethanol solution ultrasonic extraction 30min that the mass fraction of 6 times of amounts is 30% is filtered (400 mesh), merges filtered fluid twice, dense
Be reduced to medicinal material: the weight ratio of concentrate is 1:0.6 to get the Chinese medicine composition for moisturizing relieving sore-throat to nourishiing yin to clear away the lung-heat.
The Chinese medicine composition of relieving sore-throat is moisturized in 2 nourishiing yin to clear away the lung-heat of embodiment
The Chinese medicine composition of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, and the active constituent of the Chinese medicine composition is by following parts by weight
Raw material is prepared: 46 parts of great burdock achene, 16 parts of reed root, and 12 parts of Chinese olive, 13 parts of glutinous rehmannia, 11 parts of Radix Ophiopogonis, 11 parts of radix scutellariae, cortex moutan 8
Part, 13 parts of radix paeoniae rubra, 8 parts of campanulaceae, 13 parts of radix scrophulariae, 13 parts of dendrobium nobile, 11 parts of chrysanthemum, 11 parts of peppermint, 13 parts of cordate houttuynia, the root bark of white mulberry 11
Part, 6 parts of Radix Glycyrrhizae.
Nourishiing yin to clear away the lung-heat moisturize the Chinese medicine composition of relieving sore-throat the preparation method comprises the following steps:
The raw material for weighing above-mentioned parts by weight, is sufficiently mixed, and crushes, sets in ultrasonic extraction tank, is added 6 times of above-mentioned raw materials weight
The ethanol solution that the mass fraction of amount is 50%, ultrasonic extraction 30min are filtered (400 mesh), and filter residue continues using raw material weight
The ethanol solution ultrasonic extraction 30min that the mass fraction of 6 times of amounts is 10% is filtered (400 mesh), merges filtered fluid twice, dense
Be reduced to medicinal material: the weight ratio of concentrate is 1:0.6 to get the Chinese medicine composition for moisturizing relieving sore-throat to nourishiing yin to clear away the lung-heat.
The Chinese medicine composition of relieving sore-throat is moisturized in 3 nourishiing yin to clear away the lung-heat of embodiment
The Chinese medicine composition of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, and the active constituent of the Chinese medicine composition is by following parts by weight
Raw material is prepared: 52 parts of great burdock achene, 20 parts of reed root, and 15 parts of Chinese olive, 16 parts of glutinous rehmannia, 16 parts of Radix Ophiopogonis, 16 parts of radix scutellariae, cortex moutan 13
Part, 19 parts of radix paeoniae rubra, 13 parts of campanulaceae, 29 parts of radix scrophulariae, 16 parts of dendrobium nobile, 16 parts of chrysanthemum, 16 parts of peppermint, 16 parts of cordate houttuynia, the root bark of white mulberry 15
Part, 10 parts of Radix Glycyrrhizae.
Nourishiing yin to clear away the lung-heat moisturize the Chinese medicine composition of relieving sore-throat the preparation method comprises the following steps:
The raw material for weighing above-mentioned each parts by weight, is ground into middle powder, is placed in refluxing extraction tank, and above-mentioned raw materials weight 6 is added
The mass fraction of amount is ethanol solution refluxing extraction 1 time of 65% again, and extracting solution filters, and filter residue adds above-mentioned raw materials weight 3
The mass fraction of amount is ethanol solution refluxing extraction 1 time of 45% again, and extracting solution filtration merges filtrate twice, recycles ethyl alcohol simultaneously
Be concentrated into medicinal material: the weight ratio of concentrate is 1:0.6 to get the Chinese medicine composition for moisturizing relieving sore-throat to nourishiing yin to clear away the lung-heat.
The Chinese medicine composition of relieving sore-throat is moisturized in 4 nourishiing yin to clear away the lung-heat of embodiment
The Chinese medicine composition of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, and the active constituent of the Chinese medicine composition is by following parts by weight
Raw material is prepared: 46 parts of great burdock achene, 16 parts of reed root, and 12 parts of Chinese olive, 13 parts of glutinous rehmannia, 11 parts of Radix Ophiopogonis, 11 parts of radix scutellariae, cortex moutan 8
Part, 13 parts of radix paeoniae rubra, 8 parts of campanulaceae, 13 parts of radix scrophulariae, 13 parts of dendrobium nobile, 11 parts of chrysanthemum, 11 parts of peppermint, 13 parts of cordate houttuynia, the root bark of white mulberry 11
Part, 6 parts of Radix Glycyrrhizae.
Nourishiing yin to clear away the lung-heat moisturize the Chinese medicine composition of relieving sore-throat the preparation method comprises the following steps:
The raw material for weighing above-mentioned parts by weight, is sufficiently mixed, and smashes into coarse powder, the decocting of 6 times of above-mentioned raw materials weight amounts is added
Extraction 2 times is boiled, volatile oil and extracting solution, extracting solution filtration are collected, filtrate is concentrated into medicinal material: concentrate weight ratio is 1:0.6, i.e.,
Obtain the Chinese medicine composition that relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat.
The Chinese medicine composition of relieving sore-throat is moisturized in 5 nourishiing yin to clear away the lung-heat of embodiment
The Chinese medicine composition of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, and the active constituent of the Chinese medicine composition is by following parts by weight
Raw material is prepared: 46 parts of great burdock achene, 16 parts of reed root, and 12 parts of Chinese olive, 13 parts of glutinous rehmannia, 11 parts of Radix Ophiopogonis, 11 parts of radix scutellariae, cortex moutan 8
Part, 13 parts of radix paeoniae rubra, 8 parts of campanulaceae, 13 parts of radix scrophulariae, 13 parts of dendrobium nobile, 11 parts of chrysanthemum, 11 parts of peppermint, 13 parts of cordate houttuynia, the root bark of white mulberry 11
Part, 6 parts of Radix Glycyrrhizae.
Nourishiing yin to clear away the lung-heat moisturize the Chinese medicine composition of relieving sore-throat the preparation method comprises the following steps:
The raw material of above-mentioned each parts by weight is weighed, crushing is sufficiently mixed, medicinal powder is placed in extractor, and above-mentioned medicinal material weight is added
The mass fraction for measuring 6 times of amounts is ethanol solution ultrasonic extraction 1 time of 55%, and extracting solution low-speed centrifugal obtains centrifugate 1 and the dregs of a decoction
1, the high speed centrifugation again of centrifugate 1 obtains centrifugate 2；The dregs of a decoction 1 add the second that the mass fraction of 4 times of raw material weight amounts is 35%
Alcoholic solution ultrasonic extraction 1 time, extracting solution low-speed centrifugal obtains centrifugate 3 and the dregs of a decoction 2,2 abandonings of the dregs of a decoction, centrifugate 3 again at a high speed from
The heart obtains centrifugate 1, merges centrifugate 2 and centrifugate 4, is concentrated under reduced pressure (70 DEG C -75 DEG C, -0.08Mpa~-0.1Mpa), returns
Ethyl alcohol is received, is concentrated into medicinal material: Chinese medicine composition of the concentrate weight than moisturizing relieving sore-throat to nourishiing yin to clear away the lung-heat for 1:0.6.
The Chinese medicine composition of relieving sore-throat is moisturized in 6 nourishiing yin to clear away the lung-heat of embodiment
The Chinese medicine composition of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, and the active constituent of the Chinese medicine composition is by following parts by weight
Raw material is prepared: 46 parts of great burdock achene, 16 parts of reed root, and 12 parts of Chinese olive, 13 parts of glutinous rehmannia, 11 parts of Radix Ophiopogonis, 11 parts of radix scutellariae, cortex moutan 8
Part, 13 parts of radix paeoniae rubra, 8 parts of campanulaceae, 13 parts of radix scrophulariae, 13 parts of dendrobium nobile, 11 parts of chrysanthemum, 11 parts of peppermint, 13 parts of cordate houttuynia, the root bark of white mulberry 11
Part, 6 parts of Radix Glycyrrhizae.
Nourishiing yin to clear away the lung-heat moisturize the Chinese medicine composition of relieving sore-throat the preparation method comprises the following steps:
The raw material for weighing above-mentioned each parts by weight is ground into middle powder, and the mass fraction that 8 times of above-mentioned raw materials weight amounts are added is
65% ethanol solution, stirs evenly, and places 5 hours, transfers in percolation filtration extraction pot, and the matter of 10 times of raw material weight amounts is added
It measures the ethanol solution that score is 45% and carries out seepage pressure effects, diacolation speed is collected 1 liter of percolate by every kilogram of medicinal material per hour, mentioned
After the completion of taking, recycle from percolate and ethyl alcohol and be concentrated into medicinal material: the weight ratio of concentrate is 1:0.6 to get to nourishiing yin to clear away the lung-heat
Moisturize the Chinese medicine composition of relieving sore-throat.
Massage cream of relieving sore-throat and preparation method thereof is moisturized in 7 nourishiing yin to clear away the lung-heat of embodiment
The massage cream of relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, is prepared by the raw material of following weight percent: 20.0% institute
State Chinese medicine composition, 1.2% stereth -2,1.5% stereth -21,3.3% cetostearyl alcohol, 4.0% carbonic acid two
Pungent rouge, 1.6% stearine, 5.0% isopropyl myristate, 1.5% caprylic/capric triglyceride, 2.0% poly- diformazan
Radical siloxane, 0.05% bisabolol, 46.00% water, 8.0% butanediol, 2.0% glycerol, 0.23% xanthan gum, 0.2% algae
Sour sodium, 0.1%EDTA disodium, 1.0% glycine betaine, 0.6% titanium dioxide, 0.02% tetrahydro piperine, 1.0%1,3 propylene glycol,
0.6% Phenoxyethanol, 0.1% essence, as shown in table 1.
The massage cream raw material components and its weight percent of relieving sore-throat are moisturized in 1 nourishiing yin to clear away the lung-heat of table
The nourishiing yin to clear away the lung-heat moisturize the preparation method of the massage cream of relieving sore-throat the following steps are included:
One, preposition processing
(1) Chinese medicine composition that yin and clearing lung-heat moisturizes relieving sore-throat is prepared, step is the same as embodiment 2；
(2) D phase is pre-processed, accurate weighing D phase raw material after being slowly stirred wetting, crosses colloid mill circulation and is milled to fine and smooth slurry
Shape, heating water bath is to 85-90 DEG C, and insulated sterilizing 10min, spare (electromagnetic oven or other heating method pay attention to stirring at any time, keep away
Unburned paste)；
(3) E phase is pre-processed, accurate weighing E phase raw material after mixing, is stirred to being completely dissolved, can be heated at 50 DEG C or less auxiliary
Hydrotropy solution, it is spare；
(4) C phase is pre-processed, water phase pot is added in accurate weighing C phase raw material, after mixing evenly, is heated to 85-90 DEG C, heat preservation
30min sterilizing, it is spare；
Two, production technology
(1) accurate weighing A phase raw material is added oily phase pot, is heated to 85-90 DEG C under stirring, maintains this temperature 10min
Sterilizing；
(2) emulsion tank is added in accurate weighing B phase raw material, and after stirring five minutes, lasting stir (20-25r/min) starts to add
Heat is heated to 85-90 DEG C, and heat preservation 10min sterilizes, then C phase is passed through 200 mesh filter-cloth filterings, is pumped into emulsion tank, is sufficiently stirred
It mixes；
(3) A phase is passed through under 200 mesh filter-cloth filtering states, is pumped into emulsion tank, the process that is pumped into opens homogenizer, high speed
Homogeneous after exhausting, vacuumizes and maintains 0.02-0.03Mpa, continues high speed homogenization 12-15min；
(4) pretreatment D phase is poured into emulsion tank, vacuumizes and maintain 0.02-0.03Mpa, high speed homogenization 8-10min；
(5) start the lotion that cooled down with ice water, temperature-fall period persistently stirs (20-25r/min)；
(6) 60 DEG C are cooled to, pretreatment E phase is poured into, persistently stirs 5-10min；
(7) 50 DEG C are cooled to, F phase raw material is sequentially added, vacuumizes and maintain 0.04-0.05Mpa, high speed homogenization 2-4min
Afterwards, continue cooling lotion；
(8) stop stirring after lotion is cooled to 40 DEG C, discharging samples inspection, and seals lotion, moves to semi-finished product storage
Between.
The stability test of the massage cream of relieving sore-throat is moisturized in 8 nourishiing yin to clear away the lung-heat of embodiment
Nourishiing yin to clear away the lung-heat prepared by embodiment 7 is moisturized into the massage cream of relieving sore-throat respectively in 40 DEG C (heat-resisting) and -10 DEG C (cold-resistant)
Storage 15 days, observation the results show that nourishiing yin to clear away the lung-heat moisturize the massage cream of relieving sore-throat without layering and it is coarse phenomena such as, illustrate embodiment 7
The massage cream that relieving sore-throat is moisturized in the nourishiing yin to clear away the lung-heat of preparation is with good stability.
The heavy metal analysis test of the massage cream of relieving sore-throat is moisturized in 9 nourishiing yin to clear away the lung-heat of embodiment
China Guangzhou Analysis &. Test Center is entrusted, the massage cream of relieving sore-throat is moisturized to the nourishiing yin to clear away the lung-heat that embodiment 7 is prepared
The content of middle heavy metal is detected, and testing result is as shown in table 2.
The content of heavy metal in the massage cream of relieving sore-throat is moisturized in 2 nourishiing yin to clear away the lung-heat of table
| Analysis project | Inspection result | Measurement unit |
| Mercury | < 1 (qualification) | mg/kg |
| Lead | < 10 (qualifications) | mg/kg |
| Arsenic | < 1 (qualification) | mg/kg |
| Cadmium | < 2 (qualifications) | mg/kg |
The massage cream heavy metal inspection of relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat provided by the invention it can be seen from test data in table 2
It is qualified to survey result, has the advantages that safe and free of toxic and side effects.
The skin irritation test of the massage cream of relieving sore-throat is moisturized in 10 nourishiing yin to clear away the lung-heat of embodiment
Skin irritation test is carried out to rabbit using the massage cream that relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat prepared by embodiment 7.
One, experimental drug
Test side: the massage cream of relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat prepared by embodiment 7.
Control sides: physiological saline
Two, experimental animal
Healthy white experiment uses rabbit 4,2.0~3.0kg of weight, animal credit number: SCXK (Guangdong) 2014-0023.
Three, method and result
Skin irritation test method and step are according to the skin irritation test in " cosmetics health specification 2007 editions "
Method and step carry out.Wherein, it is compared using itself androgynous left and right, left side goes to hair-fields to smear nourishiing yin to clear away the lung-heat prepared by embodiment 7
The massage cream of relieving sore-throat is moisturized, right side unhairing smears physiological saline.The results are shown in Table 3 for multiple skin irritation test.
3 nourishiing yin to clear away the lung-heat of table moisturizes the massage cream of relieving sore-throat to the multiple skin irritation test result of rabbit
As can be seen from Table 3, the nourishiing yin to clear away the lung-heat that prepared by embodiment 7 moisturizes the massage cream of relieving sore-throat to the multiple skin irritatin of rabbit
Property test in, every animal average integral is 0.46 daily, and stimulus intensity evaluation is respectively less than 0.5, be it is non-stimulated, illustrate embodiment
The massage cream that relieving sore-throat is moisturized in the nourishiing yin to clear away the lung-heat of 7 preparations is nonirritant, highly-safe.
The clinical test of the massage cream of relieving sore-throat is moisturized in 11 nourishiing yin to clear away the lung-heat of embodiment
The massage cream for moisturizing relieving sore-throat to nourishiing yin to clear away the lung-heat prepared by embodiment 7 carries out clinical effect trial.
One, subject enrollment standard:
(1) men and women is unlimited, cooperation product beta test requirement；
(2) dry throat pain, dry cough lack cough or without phlegm；
(3) it can cooperate well test, be able to maintain good daily life system time and eating habit in the trial employment period.
Two, given the test agent, sample application method and time
Test group:
Given the test agent: the massage cream of relieving sore-throat, every 3mL are moisturized in nourishiing yin to clear away the lung-heat prepared by embodiment 7；
Application method: it takes given the test agent to massage in right amount and is applied to back Dazhui acupoint, fei shu cave and neighbouring position；
Use the time: two weeks, daily in the morning, afternoon and evening each 1 time.
Control group:
Given the test agent: nourishiing yin to clear away the lung-heat oral solution；
Application method: oral；
Use the time: two weeks.One time 1,2-3 times on the one.
Three, the course for the treatment of is tested
Time on probation is 2 weeks.
Four, evaluation of clinical curative effect standard
Dry throat feeling of pain disappears, and cough disappears for recovery from illness；Dry throat feeling of pain is substantially reduced, basic disappear of coughing
It is effective；Dry throat pain, unchanged cough are invalid.
Five, result on trial is analyzed
The massage cream that relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat is two weeks by a definite date on probation.
Person on probation must not be lower than 50 people.
The on probation of the massage cream of relieving sore-throat is moisturized in a total of 56 people participation nourishiing yin to clear away the lung-heat.Two groups are randomly divided into, every group of 28 people.By
During examination personnel's Evaluation product, do not occur the allergic phenomenas such as pruitus, shouting pain, redness.Test group, after test,
19 people's dry throat feeling of pains completely disappear, and cough disappears, for recovery from illness；3 people's dry throat feeling of pains are substantially reduced, and cough is basic
It disappears, is effective；6 people's dry throat pain, cough are unchanged, are invalid.Control group, after test, 12 people's dry throats
Feeling of pain completely disappears, and cough disappears, for recovery from illness；7 people's dry throat feeling of pains are substantially reduced, and basic disappearance of coughing, is effective；
9 people's dry throat pain, cough are unchanged, are invalid.Concrete outcome is such as shown in Table 4.
The massage cream clinical test results of relieving sore-throat are moisturized in 4 nourishiing yin to clear away the lung-heat of table
| The course for the treatment of | Control group | Test group |
| Recovery from illness | 19 | 12 |
| It is effective | 3 | 7 |
| In vain | 6 | 9 |
| It is efficient | 78.57% | 67.86% |
On probation by 2 weeks by a definite date it can be seen from test data in table 4, the massage cream of relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat
Effective percentage has reached 78.57%, illustrate nourishiing yin to clear away the lung-heat provided by the invention moisturize relieving sore-throat massage cream it is not only easy to use, but also
It is mild to skin it is non-stimulated, have no toxic side effect, nourishing Yin and promoting production of body fluid, promoting the dispersing function of the lung relieving sore-throat, removing heat from lung and relieving asthma is clearing heat and detoxicating, reaches comprehensive clearing lung-heat
Effect has the advantages that good effect, safety and stability.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (8)
1. the Chinese medicine external composition that relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, which is characterized in that the work of the Chinese medicine external composition
Property ingredient is prepared by following raw material: 44-52 parts of great burdock achene, 15-20 parts of reed root, and 10-15 parts of Chinese olive, glutinous rehmannia 8-
16 parts, Radix Ophiopogonis 8-16 part, 8-16 parts of radix scutellariae, 5-13 parts of cortex moutan, 11-19 parts of radix paeoniae rubra, 5-13 parts of campanulaceae, 11-29 parts of radix scrophulariae, stone
8-16 parts of dry measure used in former times, 8-16 parts of chrysanthemum, 8-16 parts of peppermint, 11-16 parts of cordate houttuynia, 10-15 parts of the root bark of white mulberry, 2-10 parts of Radix Glycyrrhizae.
2. the Chinese medicine external composition that relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat according to claim 1, which is characterized in that the Chinese medicine
The active constituent of topical composition is prepared by following raw material: 46 parts of great burdock achene, 16 parts of reed root, and 12 parts of Chinese olive,
13 parts of glutinous rehmannia, 11 parts of Radix Ophiopogonis, 11 parts of radix scutellariae, 8 parts of cortex moutan, 13 parts of radix paeoniae rubra, 8 parts of campanulaceae, 13 parts of radix scrophulariae, 13 parts of dendrobium nobile, chrysanthemum
11 parts, 11 parts of peppermint, 13 parts of cordate houttuynia, 11 parts of the root bark of white mulberry, 6 parts of Radix Glycyrrhizae.
3. the preparation method of the Chinese medicine external composition of relieving sore-throat is moisturized in the described in any item nourishiing yin to clear away the lung-heat of claim 1-2, special
Sign is, comprising the following steps: weighs the raw material, it is 10- that water or the mass fraction that 3-10 times of the raw material weight is measured, which is added,
70% ethanol solution extracts 1-2 times, filtering or centrifugation, obtains the Chinese medicine external composition after concentrating filter liquor；It is described
The method of extraction is to decoct extraction method or reflux extraction or ultrasonic extraction or permeating extraction.
4. the preparation method of the Chinese medicine external composition of relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat according to claim 3, feature exists
In, comprising the following steps: the raw material is weighed, the ethanol solution that the mass fraction that 6 times of raw material weight amounts are added is 50% is super
Sound extracts, filtering, and filter residue continues to use the mass fraction of 6 times of raw material weight amounts for 10% ethanol solution ultrasonic extraction, filters,
Merging filtrate is concentrated into medicinal material: the weight ratio of concentrate is 1:0.6 to get the Chinese medicine external group for moisturizing relieving sore-throat to nourishiing yin to clear away the lung-heat
Close object.
5. the described in any item nourishiing yin to clear away the lung-heat of claim 1-2 moisturize the Chinese medicine external composition of relieving sore-throat in preparation nourishiing yin to clear away the lung-heat profit
Application in the Chinese medicine external product of dry relieving sore-throat.
6. the massage cream that relieving sore-throat is moisturized in a kind of nourishiing yin to clear away the lung-heat, which is characterized in that the massage cream is by any one of claim 1-2
The Chinese medicine external composition of relieving sore-throat is moisturized in the nourishiing yin to clear away the lung-heat and matrix or carrier are prepared.
7. the massage cream that relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat according to claim 6, which is characterized in that the nourishiing yin to clear away the lung-heat is moisturized
Weight percent of the Chinese medicine external composition of relieving sore-throat in the massage cream is 10.0-30.0%；The Chinese medicine external composition
Relative density at 55 DEG C -65 DEG C is 1.05-1.25.
8. the massage cream that relieving sore-throat is moisturized in nourishiing yin to clear away the lung-heat according to claim 7, which is characterized in that the massage cream be by with
The raw material of lower weight percent is prepared: Chinese medicine external composition described in 15.0-23.0%, 43.0-46.0% water, 3.5-5.5%
Emulsifier, 2.5-4.5% excipient, 11.5-13.5% emollients, 0.05-0.09% conditioner, 11.0-13.0% moisturizer, 0.4-
0.6% suspending agent, 0.1-0.2% chelating agent, 0.4-0.8% covering agent, 0-1.0% preservative, 0-0.3% essence.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510439367.8A CN106389895B (en) | 2015-07-22 | 2015-07-22 | Chinese medicine composition of relieving sore-throat and its preparation method and application is moisturized in nourishiing yin to clear away the lung-heat |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510439367.8A CN106389895B (en) | 2015-07-22 | 2015-07-22 | Chinese medicine composition of relieving sore-throat and its preparation method and application is moisturized in nourishiing yin to clear away the lung-heat |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106389895A CN106389895A (en) | 2017-02-15 |
| CN106389895B true CN106389895B (en) | 2019-10-08 |
Family
ID=58008504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510439367.8A Active CN106389895B (en) | 2015-07-22 | 2015-07-22 | Chinese medicine composition of relieving sore-throat and its preparation method and application is moisturized in nourishiing yin to clear away the lung-heat |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106389895B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103301408A (en) * | 2013-06-28 | 2013-09-18 | 珠海圣原生物科技有限公司 | Traditional Chinese medicine extract and massage cream prepared from extract |
| CN103861018A (en) * | 2012-12-10 | 2014-06-18 | 马建民 | Traditional Chinese medicine for treating sore throat |
| CN104083709A (en) * | 2014-06-16 | 2014-10-08 | 范健身 | Traditional Chinese medicinal composition for treating cold pharyngalgia, and preparation method thereof |
| CN104587249A (en) * | 2015-01-12 | 2015-05-06 | 曹成瑞 | Traditional Chinese medicine composition with effects of clearing lung, moistening dryness and relieving sore throat as well as preparation method and application thereof |
-
2015
- 2015-07-22 CN CN201510439367.8A patent/CN106389895B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103861018A (en) * | 2012-12-10 | 2014-06-18 | 马建民 | Traditional Chinese medicine for treating sore throat |
| CN103301408A (en) * | 2013-06-28 | 2013-09-18 | 珠海圣原生物科技有限公司 | Traditional Chinese medicine extract and massage cream prepared from extract |
| CN104083709A (en) * | 2014-06-16 | 2014-10-08 | 范健身 | Traditional Chinese medicinal composition for treating cold pharyngalgia, and preparation method thereof |
| CN104587249A (en) * | 2015-01-12 | 2015-05-06 | 曹成瑞 | Traditional Chinese medicine composition with effects of clearing lung, moistening dryness and relieving sore throat as well as preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106389895A (en) | 2017-02-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103417947B (en) | Chinese medicine extract of warming and recuperating the kidney-YANG and preparation method thereof and the kidney warming NUANQIGAO | |
| CN103316219A (en) | Traditional Chinese medicinal preparation for treating phthisis and preparation method thereof | |
| CN103520505B (en) | Traditional Chinese medicine preparation for treating neurasthenia and preparation method thereof | |
| CN104825914A (en) | Traditional Chinese medicinal preparation for assisted treatment of breast cancer | |
| CN104013868A (en) | Traditional Chinese medicine composition for treating chronic obstructive pulmonary disease and preparation method thereof | |
| CN104223297B (en) | A kind of schisandra chinensis health-care oral liquid of slow down aging and preparation method thereof | |
| CN115414458B (en) | A Chinese medicinal composition for treating hepatitis B, and its preparation method | |
| CN111588804A (en) | Medicinal and edible formula for tonifying primordial qi | |
| CN103735610A (en) | Granule for relieving body fatigue | |
| CN105920269A (en) | Health-care medicinal liquor for females | |
| CN106334171B (en) | A kind of Chinese medicine preparation and preparation method for being used to repair hepatic injury | |
| CN106389895B (en) | Chinese medicine composition of relieving sore-throat and its preparation method and application is moisturized in nourishiing yin to clear away the lung-heat | |
| CN112138084B (en) | Traditional Chinese medicine composition for treating bronchiectasis qi-yin deficiency and phlegm-heat obstructing lung and application thereof | |
| CN102049010B (en) | Medicament for preventing and treating ischemic cerebrovascular diseases | |
| CN106344888B (en) | Chinese medicine composition and its preparation method and application with strengthening the spleen and replenishing qi function | |
| CN114748603A (en) | Medicine-food homologous composition for preventing and treating new coronavirus pneumonia variation or compound yang and application | |
| CN102357151A (en) | Chinese medicinal composition for delaying senility and preparation process thereof | |
| CN105213807A (en) | Be used for the treatment of the medicine of type of hyperactivity of fire caused by deficiency of YIN recurrent oral ulceration | |
| CN104984206B (en) | Pediatric spleen-reinforcing digestion-promoting Chinese medicine composition and its preparation method and application and its creme | |
| CN105213905A (en) | A kind of Chinese medicine composition and application thereof preventing and treating postmenopausal osteoporosis | |
| CN104706978A (en) | Medicine for treating gingivitis caused by kidney yin deficiency and preparation method of medicine | |
| CN108853340A (en) | A kind of Chinese medicine of nourishing the liver and kidney and preparation method thereof | |
| CN108434217A (en) | A kind of pharmaceutical composition and preparation method thereof for neck, shoulder, arm pain rehabilitation | |
| CN104887757B (en) | The Chinese medicine composition and massage cream of freeing vessels and nourishing heart | |
| CN105148038A (en) | Traditional Chinese medicine pills for treating adverse reactions after CT examination and preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |