CN106389473A - Drug for treating allergic rhinitis and preparation method thereof - Google Patents

Abstract

The invention relates to a drug for treating allergic rhinitis and a preparation method thereof. The drug is prepared from one component a honeycomb (apiary) and is obtained by cutting the honeycomb into small pieces, cleaning the small pieces with warm water, pouring the small pieces into an extraction tank, performing water extraction according to the weight proportion of 1 to 50 and filtering out an extracting solution. The drug is free of toxic and side effects, easy to absorb and suitable for treatment of the allergic rhinitis. The invention further discloses a preparation method of the drug for treating the allergic rhinitis.

Description

A kind of for treating medicine of allergic rhinitis and preparation method thereof

Technical field

The present invention is ethnic drug towards medicine preparation and in particular to a kind of treat medicine of allergic rhinitis and preparation method thereof.

Background technology

China there are about 200,000,000 people and suffers from anaphylactia, and wherein more than 100,000,000, people suffers from allergic rhinitis.Serious allergia nose Inflammation about 70% can affect to sleep, and 94% influences whether live and work.Its impact to quality of life has been even more than hypertension, sugar The major diseases such as urine disease, and allergic rhinitis is possible to multiple diseases such as merging tympanitis, nasosinusitis, nasal polyp, asthma, to strong The harm of health is bigger.In China, anaphylactia illness rate is in obvious ascendant trend, central with allergic rhinitis with asthma the most Generally.Domestic multinomial investigational data shows, sagebruss sand sagebrush (Artemisia filifolia), alkali wormwood artemisia pollen are to cover west, North Shaanxi allergic rhinitis and mistake The main pollen of quick property asthma.Additionally, various chemical substances, some food, medicine, cosmetics, urban atmospheric pollution thing If vehicle exhaust etc. is it is also possible to lead to allergic rhinitis.Allergic rhinitis abbreviation allergic rhinitis, typically also known as anaphylaxis Rhinitis, is the allergy occurring in schneiderian membrane, is also the common form of expression of allergic airway disease, sometimes roars with bronchus Breathe heavily and exist simultaneously.This sick incidence of disease dramatically increased at nearly 20 years and warms up, particularly true in developed country.Age of onset is with blue or green strong Based on year, but have now found that child patient also more typically.Although the incidence of disease no significant difference in sex, female sex hormone can plus Weight allergy.Including seasonal rhinitis and perennial rhinitis.Clinically there are acute rhinitis, rhinitis chronic（Chronic simple nose Inflammation, chronic hypertrophic rhinitis, chronic rhinitis sicca）, rhinitis sicca, atrophic rhinitis, caseous rhinitis, Drug nose Inflammation, vasomotor rhinitis, the non-allergic rhinitis of eosinophilia, too strong reflectivity rhinitis etc..Allergy Rhinitis is medium (mainly histamine) release being mediated by IgE after atopic individuals contact sensibiligen, and has panimmunity activity The schneiderian membrance chronic inflammatory reaction disease of the participation such as cell and cell factor, with rhiocnesmus, sneeze, nose hypersecretion, schneiderian membrance Swelling etc. is main feature.This sick clinic is often divided into perennial allergic rhinitis and pollinosis, and the latter is also called " pollinosis ".Although allergic rhinitis are not a kind of serious diseases, daily life, study and the work of patient can be affected Efficiency, and cause heavy burden economically, can induce bronchial astehma, nasosinusitis, nasal polyp, tympanitis etc., or with change Answer membranous conjunctivitis to occur simultaneously.Allergic rhinitis are often with to contact allergen relevant.Recently research have indicated that, h and E is also to become The key factor of answering property rhinitis：1. allergenic effect mainly has three kinds of modes in individuality：1. suck allergen：Indoor allergen master Dust mite to be had, animal skin or the anaphylactogen from plant etc.；Outdoor allergen includes pollen and fungi etc.；2. eat allergic effect Former：Common person such as milk, egg, meat, fishes and shrimps and other seafood delights and some drugses etc.；3. directly contact allergen：As made up Product, soap, paint and some external medicinal liquids.2. inherent cause：Allergic disease is a chronic progression process, with heredity Relevant.In terms of Point of View of Clinical, allergic rhinitis patients are often accompanied by obvious family history.3. environmental factor：1. air pollution：Outdoor dirty Dye is mainly derived from motor vehicle and atmosphere pollution composition, such as ozone, nitrogen oxides and SO2 etc.；2. indoor pollution mainly have formaldehyde, Toluene etc., allergic rhinitis can induce bronchial astehma, nasosinusitis, nasal polyp, tympanitis, or send out with allergic conjunctivitis simultaneously Raw.The clinical manifestation of allergic rhinitis early stage has：Sneeze（The daily outbreak of paroxysmal for several times, how from morning or night or contact Show effect at once after anaphylactogen）, clear tears（A large amount of clear water sample nasal mucus, sometimes can not feel and drip from nostril）, nasal obstruction（Interval or hold Continuous, unilateral or bilateral, light and heavy degree differs）, rhiocnesmus（Most patients intranasal is itched, pollinosis patient can itch with eye, ear itching and Pharynx is itched）, partly with hyposphresia.Symptom continues a few minutes every time, recurrent exerbation, and in perennially or Seasonal Incidence.Mesh It is inconspicuous that the medicine generally existings of the great majority treatment allergic rhinitises occurring on front market take rear therapeutic effect, repeatedly sends out Work, the problem of large side effects.

Content of the invention

The invention aims to overcoming the shortcomings of that prior art exists, and one kind is provided to be used for treating allergic rhinitis Medicine and preparation method thereof, drug administration safety of the present invention, the more existing similar drug more remarkable treatment effect than in the market, and Have no toxic side effect.

The object of the present invention is achieved like this：

A kind of medicine for treating allergic rhinitis, is made up of following method：

Take honeycomb, honeycomb is cut into small pieces, after being cleaned with warm water, pour in extractor, with 1:50 part by weight water extracts, filter Go out extract to obtain final product.

A kind of preparation method of the medicine for treating allergic rhinitis as above, comprises the following steps：

1. take honeycomb, honeycomb is cut into small pieces, after being cleaned with warm water, pour in extractor, plus the water immersion 1 of 50 times of weight is little Shi Hou, with normal heating refluxing extraction 2 hours, leaches extract；

2. extract put cool after dispensed, every bottle of filling 200ml.

The present invention is towards medicine formulation art, belongs to towards medicine and pharmacology.Towards medicine and pharmacology be one of Traditional Chinese doctors ' pharmacy important Part.It is on the basis of Korean nationality's inherently culture and traditional medicine, absorb the theory of traditional Chinese medicine and pharmacy, anti-in conjunction with oneself The practice that disease is cured the disease, gradually forms the traditional medicine system with unique theoretical and abundant clinical experience.

Honeycomb in the present invention（I.e. honeycomb）：Rich in protein, iron, calcium etc., dental caries and toothache can be treated, sore swollen toxin, Acute mastitis, scrofula, skin stubborn dermatitis, the fungal infection of the hand, allergic constitution.Honeycomb water extract all has very to bacterium, fungus-caused disease Good therapeutic effect.Honeycomb（Honeycomb）The pharmacological research of water extract shows, 1. to staphylococcus aureus, Pseudomonas aeruginosa, big Enterobacteria, shigella dysenteriae and typhoid bacillus etc. have compared with high inhibition effect；2. to aspergillus fumigatus, aspergillus flavus, eggplant sickle bacterium, beading bacterium There is obvious inhibiting effect Deng fungi；3. there is antiviral effect, can make hepatitis increase appetite, improve the health care of sleep, increase to Drag, promotion transaminase reduce；4. cholesterol in blood plasma can be made to be decreased obviously, have and reduce blood pressure and increase hematoblastic work( Effect.

Using method：Take the honeycomb preparing every time（Honeycomb）Extract one bottle of liquid（200ml/ bottle）, liquid is poured into directly In the canister of footpath 15 cm, heated boiled after, leave heating burning things which may cause a fire disaster or heating furnace, be placed on while hot below nose, Sniffed after the steam 10～15 minutes of liquid evaporation with nose, treat honeycomb（Honeycomb）Disposably take after extracting fluid temperature appropriateness Complete, treat secondary daily in the same way, a course for the treatment of is 30 days.

Drug administration safety of the present invention, evident in efficacy, have no toxic side effect, compensate for the breach of similar drug.Therefore, have Wide market prospects, will produce considerable economic benefit.

For confirming the validity of medicine of the present invention, select case 60, wherein male patient 30, female patient 30 altogether Name.Wherein 50 patients symptomatic are clearly better, and obvious effective rate reaches 83.3%；55 patients symptomatic improve, and efficient reach 91.7%.

Typical clinical example（Yan Bianchao doctor hospital provides）

Example 1：Lee, female, people from county of Wangqing, 31 years old, certain company clerk.Patient suffers from allergic rhinitis more than 4 years, often has nose The symptom such as fill in, have a running nose, sneezing.Mad must sneeze battle array every morning to make, after voluntarily medication fail to respond to any medical treatment fruit, recurrent exerbation is after 2 years, It is still nasal mucus such as clear water, severe nasal blockage, with headache, and now start had slight asthma to occur, be often in flu shape State.Endoscopy checks it is believed that nasal cavity nasal decongestion oedema, and hypertrophic inferior turbinate is it is seen that watery secretion.Take the present invention After two months, allergic manifestation disappears drug therapy, and asthma is also eased, and the surface of a wound is cured substantially.

Example 2：Gold certain, female, Jilin Province Yanji people, 26 years old, civil servant.Year more than sneeze runny nose number from morning, through anti-inflammatory, Antianaphylactic treatment, effective at that time, again recurrent exerbation afterwards.Through examination in hospital, schneiderian membrane is pale, plump, substantial amounts of thin in nasal cavity Secretion, is allergic rhinitis.Take drug therapy of the present invention after one month, allergic manifestation disappears, basic healing.

Example 3：Guo, man, people from Antu, Jilin Province, 38 years old, teacher.Recurrent exerbation allergic rhinitis more than 3 years, nearly one Sensory symptoms increases within many months, just have a stuffy nose when every morning gets up, rhiocnesmus, sneeze repeatedly, flow light tears, forehead and the vexed pain of glabella, head Brain dusk covers, very painful.Run into cold air substantially to violate, often catch a cold, anemophobia is cold, spontaneous perspiration, with waist soreness, enuresis nocturna frequency Numerous.Take drug therapy of the present invention after two months, allergic rhinitis is cured substantially, asthma is also eased.

Specific embodiment

A kind of medicine for treating allergic rhinitis, is made up of following method：Take honeycomb, honeycomb be cut into small pieces, After being cleaned with warm water, pour in extractor, with 1:50 part by weight water extracts, and leaches extract and obtains final product.

A kind of preparation method of the medicine for treating allergic rhinitis as above, comprises the following steps：

1. take honeycomb, honeycomb is cut into small pieces, after being cleaned with warm water, pour in extractor, plus the water immersion 1 of 50 times of weight is little Shi Hou, with normal heating refluxing extraction 2 hours, leaches extract；

2. extract put cool after dispensed, every bottle of filling 200ml.

The purposes of the embodiment of the present invention is merely to illustrate the present invention, and is not intended to limit the scope of the invention.Additionally, readding After having read the technology contents of the present invention, those skilled in the art can make various changes, modification or modification to the present invention, owns These equivalent form of values also belong within the protection domain that the present patent application appended claims are limited.

Claims (2)

1. a kind of medicine for treating allergic rhinitis, is made up of following method：

Take honeycomb, honeycomb is cut into small pieces, after being cleaned with warm water, pour in extractor, with 1:50 part by weight water extracts, filter Go out extract to obtain final product.

2. a kind of preparation method of the medicine for treating allergic rhinitis as claimed in claim 1, comprises the following steps：

1. take honeycomb, honeycomb is cut into small pieces, after being cleaned with warm water, pour in extractor, plus the water immersion 1 of 50 times of weight is little Shi Hou, with normal heating refluxing extraction 2 hours, leaches extract；

2. extract put cool after dispensed, every bottle of filling 200ml.