CN106344861A - Traditional Chinese medicine compound for treating chronic superficial gastritis - Google Patents
Traditional Chinese medicine compound for treating chronic superficial gastritis Download PDFInfo
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- CN106344861A CN106344861A CN201610995415.6A CN201610995415A CN106344861A CN 106344861 A CN106344861 A CN 106344861A CN 201610995415 A CN201610995415 A CN 201610995415A CN 106344861 A CN106344861 A CN 106344861A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
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Abstract
The invention discloses a traditional Chinese medicine compound for treating chronic superficial gastritis. The traditional Chinese medicine compound comprises the following materials in parts by weight: 5-9 parts of pepper, 4-7 parts of semen coicis, 7-14 parts of tremella, 6-9 parts of piperis longi, 3-11 parts of illicium verum, 4-13 parts of hawthorn, 6-10 parts of fingered citron, 5-9 parts of rhizoma galangae and 7-12 parts of fructus aurantii. The invention researches and develops a traditional Chinese medicine formula capable of effectively relieving chronic superficial gastritis, recovering vitality, promoting appetite and protecting the gastric mucosa by researching the pathogenesis of chronic superficial gastritis and according to the years of experiences in treating chronic superficial gastritis with the traditional Chinese medicines. After the traditional Chinese medicine compound is orally taken for a period of time, the times of diarrhea and stomachache can be obviously reduced, the symptoms, such as, abdominal distension, anorexia, belching and nausea, can be obviously relieved, the functions of regulating the intestines and stomach, promoting qi circulation to relieve pain, invigorating the spleen to promote digestion, lowering the adverse flow of qi and relieving nausea, dissolving lumps and resolving masses, and the like, can be achieved, and the traditional Chinese medicine compound is free from toxic or side effect.
Description
Technical field
The present invention relates to tcm field, specifically refer to a kind of Chinese medicine composition treating chronic superficial gastritiss.
Background technology
Chronic gastritiss lack specific symptom, and the weight of symptom is with the lesion degree of gastric mucosa and non-uniform.Most of diseases
People is often asymptomatic or has the different indigestion symptom of degree such as upper abdomen dull pain, loss of appetite, post-prandial fullness, acid regurgitation etc..Symptom
Usually recurrent exerbation, irregularities are suffered from abdominal pain, and pain often arises in feeding process or after the meal, most be located at epigastrium, umbilicuss week,
Some patientss position is not fixed, and the lighter's intermittence dull pain or dull pain, severe patient are violent angor.
It is known that chronic superficial gastritiss are for the modal pathological changes of gastric mucosa, gastric antrum portion is most common.Pathological changes are multifocal
Or diffusivity, the visible mucous hyperemia of gastroscope, edema, peony, there are the secretions of canescence or lark on surface, sometimes with point-like
Bleeding or erosion.Under mirror visible inflammatory lesion be located at mucosa shallow-layer, predominantly lymphocyte and plasmocyte infiltrating, sometimes visible few
Amount e, n.Mucosa shallow-layer can have edema, petechial hemorrhage and epithelium necrosis to come off.Chronic superficial gastritiss some patientss early stage can be no
Symptom, is mainly shown as upper abdominal pain or discomfort, big belly, early satiety, belch, the indigestion symptom such as nausea.Autoimmunity stomach
Scorching patient can be with anemia, in typical pernicious anemia in addition to anemia, also can be with other clinical tables of vitamin b12 shortage
Existing.The clinical treatment to chronic superficial gastritiss, the mainly antiacid, acid-suppressing medicine of application, rush digestive tract power reinforcing medicine, gastric mucosal protection medicine,
Autoimmune gastritis be there is no at present with special treatment, after major corrections anemia, improve clinical symptoms.Application Western medicine is mainly right
Disease is processed, mitigation symptoms.
Content of the invention
It is an object of the invention to provide a kind of can be from inside to outside fundamentally in effectively solving chronic superficial gastritiss
Drug composition.
The present invention is achieved through the following technical solutions: a kind of Chinese medicine composition for treating chronic superficial gastritiss, with
Weight portion represents, 5 ~ 9 parts of Pericarpium Zanthoxyli, 4 ~ 7 parts of Semen Coiciss, 7 ~ 14 parts of Tremella, 6 ~ 9 parts of Fructus Piperis Longi, 3 ~ 11 parts of Fructus Anisi Stellati, Fructus Crataegi cuneatae 4 ~
13 parts, 6 ~ 10 parts of Fructus Citri Sarcodactylis, 5 ~ 9 parts of Rhizoma Alpiniae Officinarum, 7 ~ 12 parts of Fructus Aurantii.
A kind of crude drug pharmacology of Chinese medicine composition for treating chronic superficial gastritiss of the present invention:
Pericarpium Zanthoxyli: warm in nature, acrid in the mouth.Returns spleen warp, stomach, kidney channel.Warming middle-JIAO to relieve pain, killing parasites for relieving itching.Belong to drugs for dispelling internal cold.
Semen Coiciss: cool in nature, sweet in the mouth, light.Returns spleen warp, stomach, lung meridian.Invigorating spleen to remove dampness, remove numbness antidiarrheal, clearing away heat and discharging pus.Belong to profit
The stranguria-relieving diuretic of water eliminating dampness by diuresis medicine subordinate classification.
Tremella: mild-natured, sweet in the mouth.Return lung warp, stomach, kidney channel.The lung moistening and production of body fluid promoting, tonifying-Yin and nourishing-stomach.Belong to qi-restoratives medicine subordinate classification
YIN-tonifying drug.
Fructus Piperis Longi: acrid in the mouth, property heat.Return stomach, large intestine channel.Warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving.Belong to drugs for dispelling internal cold.
Fructus Anisi Stellati: warm in nature, acrid in the mouth.Return liver warp, kidney channel, spleen channel, stomach.Warming YANG to expel cold, regulating QI to relieve pain.Belong to drugs for dispelling internal cold.
Fructus Crataegi cuneatae: slightly warm in nature, sour in the mouth, sweet.Returns spleen warp, stomach, Liver Channel.Removing food stagnancyization is stagnant, dispelling the stagnated QI dissipating blood stasis.Belong to QI regulating medicine.
Fructus Citri Sarcodactylis: warm in nature, acrid in the mouth, hardship, acid.Return lung warp, spleen channel, Liver Channel.Liver-smoothing, qi-regulating and stomach and alleviating pain.Belong to QI regulating medicine.
Rhizoma Alpiniae Officinarum: property heat, acrid in the mouth.Returns spleen warp, stomach.Stomach warming preventing or arresting vomiting, dispersing cold for relieving pain.Belong to drugs for dispelling internal cold.
Fructus Aurantii: warm in nature, bitter in the mouth, pungent, sour.Returns spleen warp, stomach.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.Belong to QI regulating medicine.
For optimizing the effect of drugs of medicine, further determine that, described Pericarpium Zanthoxyli is 5 parts, 6 parts of Semen Coiciss, 3 parts of Tremella, Fructus Piperis Longi
10 parts, 6 parts of Fructus Anisi Stellati, 10 parts of Fructus Crataegi cuneatae, 11 parts of Fructus Citri Sarcodactylis, 7 parts of Rhizoma Alpiniae Officinarum, 7 parts of Fructus Aurantii.
For optimizing the effect of drugs of medicine, further determine that, described Pericarpium Zanthoxyli is 7 parts, 4 parts of Semen Coiciss, 8 parts of Tremella, Fructus Piperis Longi 9
Part, 6 parts of Fructus Anisi Stellati, 7 parts of Fructus Crataegi cuneatae, 6 parts of Fructus Citri Sarcodactylis, 7 parts of Rhizoma Alpiniae Officinarum, 8 parts of Fructus Aurantii.
For optimizing the effect of drugs of medicine, further determine that, described Pericarpium Zanthoxyli is 8 parts, 5 parts of Semen Coiciss, 11 parts of Tremella, Fructus Piperis Longi
8 parts, 9 parts of Fructus Anisi Stellati, 5 parts of Fructus Crataegi cuneatae, 8 parts of Fructus Citri Sarcodactylis, 5 parts of Rhizoma Alpiniae Officinarum, 7 parts of Fructus Aurantii.
For optimizing the effect of drugs of medicine, further determine that, described Pericarpium Zanthoxyli is 5 parts, 7 parts of Semen Coiciss, 13 parts of Tremella, Fructus Piperis Longi
6 parts, 10 parts of Fructus Anisi Stellati, 4 parts of Fructus Crataegi cuneatae, 9 parts of Fructus Citri Sarcodactylis, 9 parts of Rhizoma Alpiniae Officinarum, 11 parts of Fructus Aurantii.
For optimizing the effect of drugs of medicine, further determine that, described Fructus Citri Sarcodactylis are gold bergamot.
The present invention compared with prior art, has advantages below and a beneficial effect:
The present invention passes through to study the pathogeny of chronic superficial gastritiss, and according to treatment by Chinese herbs chronic superficial gastritiss for many years
Experience is developed and a kind of can effectively be alleviated chronic superficial gastritiss symptom, rebuild one's physical constitution, increase appetite and protect gastric mucosa
Chinese medicine formula, and by the oral medication of a period of time, can substantially reduce diarrhoea and stomachache number of times, and be obviously improved abdominal distention,
The symptoms such as anorexia, eructation, nausea, reach the intestines and stomach coordinating, promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion, stopping nausea and vomiting by lowering the adverse flow of QI, the function such as dissolving lump and resolving mass,
Have no toxic side effect.
Specific embodiment
Embodiments of the invention are described below in detail.
Embodiment 1:
A kind of Chinese medicine composition for treating chronic superficial gastritiss of the present embodiment, is represented with weight portion, with weight portion table
Show, including 5 ~ 9 parts of Pericarpium Zanthoxyli, 4 ~ 7 parts of Semen Coiciss, 7 ~ 14 parts of Tremella, 6 ~ 9 parts of Fructus Piperis Longi, 3 ~ 11 parts of Fructus Anisi Stellati, Fructus Crataegi cuneatae 4 ~ 13
Part, 6 ~ 10 parts of Fructus Citri Sarcodactylis, 5 ~ 9 parts of Rhizoma Alpiniae Officinarum, 7 ~ 12 parts of Fructus Aurantii.
The preparation method of medicine of the present invention, comprises the following steps:
(1) represented with weight portion, weigh 5 ~ 9 parts of Pericarpium Zanthoxyli, 4 ~ 7 parts of Semen Coiciss, 7 ~ 14 parts of Tremella, 6 ~ 9 parts of Fructus Piperis Longi, Fructus Anisi Stellati 3 ~
11 parts, 4 ~ 13 parts of Fructus Crataegi cuneatae, 6 ~ 10 parts of Fructus Citri Sarcodactylis, 5 ~ 9 parts of Rhizoma Alpiniae Officinarum, 7 ~ 12 parts of Fructus Aurantii, and Chinese herb is put into leaching in water
Bubble 15 ~ 20 minutes;
(2) all Chinese herbs are put in glass extraction pot, then carry out Chinese herb extraction using steam heating;
(3) extracting solution is transferred in heater and carries out heating sterilization;
(4) finally the liquid after sterilization is transferred in concentration tank and is concentrated;
(5) concentrated solution is transferred to heater and carries out post bake sterilization processing;
(6) finally the concentrated solution after sterilization is transferred in spray drying tower and is dried, the powdery granule of last output is
For medicament.
Embodiment 2:
A kind of Chinese medicine composition for treating chronic superficial gastritiss of the present embodiment, is represented with weight portion, and described Pericarpium Zanthoxyli is 7
Part, 4 parts of Semen Coiciss, 8 parts of Tremella, 9 parts of Fructus Piperis Longi, 6 parts of Fructus Anisi Stellati, 7 parts of Fructus Crataegi cuneatae, 6 parts of Fructus Citri Sarcodactylis, 7 parts of Rhizoma Alpiniae Officinarum, 8 parts of Fructus Aurantii.
Embodiment 3:
A kind of Chinese medicine composition for treating chronic superficial gastritiss of the present embodiment, is represented with weight portion, and described Pericarpium Zanthoxyli is 8
Part, 5 parts of Semen Coiciss, 11 parts of Tremella, 8 parts of Fructus Piperis Longi, 9 parts of Fructus Anisi Stellati, 5 parts of Fructus Crataegi cuneatae, 8 parts of Fructus Citri Sarcodactylis, 5 parts of Rhizoma Alpiniae Officinarum, Fructus Aurantii 7
Part.
Embodiment 4:
A kind of Chinese medicine composition for treating chronic superficial gastritiss of the present embodiment, is represented with weight portion, and described Pericarpium Zanthoxyli is 5
Part, 7 parts of Semen Coiciss, 13 parts of Tremella, 6 parts of Fructus Piperis Longi, 10 parts of Fructus Anisi Stellati, 4 parts of Fructus Crataegi cuneatae, 9 parts of Fructus Citri Sarcodactylis, 9 parts of Rhizoma Alpiniae Officinarum, Fructus Aurantii 11
Part.
Using medicine of the present invention be directed to various chronic superficial gastritiss patients clinical statisticses data:
Through the Clinical practice of 200 patients, wherein male patient 121, female patient 79, medication age object 17 ~ 49 years old.Wherein
Minimum 18 years old, maximum 48 years old, 29 years old mean age;Slight chronic superficial gastritiss case 114, moderate chronic superficial gastritiss
Case 58, severe chronic superficial gastritiss case 28.
Its mild or moderate chronic superficial gastritiss patient's symptom is: patient feels inappetence, nausea, acid regurgitation easily
Situation, the situation of abdominal distention also usually occurs;
Moderate chronic superficial gastritiss patient's symptom is: the symptom of diarrhoea stomachache in patient, and in a period of time, nausea is vomitted
Tell, lassitude;
Severe chronic superficial gastritiss: patient occurs violent angor, and gastric mucosa is impaired, the situation such as have anemia to become thin, and go out
Existing constipation, hematemesis.The symptoms such as melena.
Model case:
1st, pungent certain, female, 19 years old, the previous day, because of umbilicuss week pain 3 hours, increased with vomiting 30 minutes to take and be hospitalized for treatment, be admitted to hospital
First 3 hours, patient failed to understand that umbilicuss week pain in inducement, starts to bear, increases in progressive, with abdominal distention, over the past half year after sense activity
Uncomfortable in chest, tachypnea, no nausea, no vomit, no cough, expectoration, apnea is difficult, no heating, shiver with cold and the special discomfort such as twitch, one
Directly processed, urine amount is normal.Before 30 minutes, above-mentioned symptom increases with vomiting, is gastric content, relevant with feed, and essence
Refreshing appetite poor appetite, urine is normal.Leave hospital after the treatment slightly relief of symptoms of local hospital, but afterwards and recurred, then
The Chinese medicine formula beginning to use the present invention is treated, and after the taking of 4 courses for the treatment of, around patient's umbilicuss, pain symptom delays
Solution, and do not have recurrence to occur, and the situation of tachypnea uncomfortable in chest is also gradually improved.
2nd, Zhu, female, 26 years old, umbilicuss week pain in front no obvious inducement more than Yu Yinian, is persistence severe pain, paroxysmal adds
Play, no radiating pain, with nausea, malaise, no vomit.To outpatient clinic, row plain abdominal radiograph and blood routine examination no abnormality seen,
Give the symptomatic treatments such as antiinflammatory, spasmolytic, after treatment, stomachache is alleviated.Hereafter repeatedly, the treatment symptom such as antiinflammatory, spasmolytic can for colic symptoms
Alleviate.Front more than August stomachache again to going to a doctor, and row ultrasonic examination is shown: cholelithiasises, silt sample.Abdomen occurred before 1 week again
Bitterly, no Nausea and vomiting, no suffers from diarrhoea, no generates heat, and surpasses to medical row b and shows: rectal sinuses hydrops, gives antiinflammatory, spasmolytic treatment, symptom
Alleviate, but recur afterwards again, the symptoms such as nausea diarrhoea occur, then takes the Chinese medicine formula of the present invention, after starting two courses for the treatment of
Diarrhoea colic symptoms make moderate progress and not in recurrence, and vomiting and diarrhoea symptom is also thoroughly improved, patient mental's recovering state.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that: not
Multiple changes, modification, replacement and modification can be carried out to these embodiments under the principle of the disengaging present invention and objective, the present invention's
Scope is limited by claim and its equivalent.
Claims (5)
1. a kind of Chinese medicine composition treating chronic superficial gastritiss it is characterised in that: represented with weight portion, including Pericarpium Zanthoxyli 5 ~ 9
Part, 4 ~ 7 parts of Semen Coiciss, 7 ~ 14 parts of Tremella, 6 ~ 9 parts of Fructus Piperis Longi, 3 ~ 11 parts of Fructus Anisi Stellati, 4 ~ 13 parts of Fructus Crataegi cuneatae, 6 ~ 10 parts of Fructus Citri Sarcodactylis, high
5 ~ 9 parts of Rhizoma Alpiniae Officinarum, 7 ~ 12 parts of Fructus Aurantii.
2. a kind of Chinese medicine composition treating chronic superficial gastritiss according to claim 1 it is characterised in that: described flower
Green pepper is 7 parts, 4 parts of Semen Coiciss, 8 parts of Tremella, 9 parts of Fructus Piperis Longi, 6 parts of Fructus Anisi Stellati, 7 parts of Fructus Crataegi cuneatae, 6 parts of Fructus Citri Sarcodactylis, 7 parts of Rhizoma Alpiniae Officinarum, trifoliate orange
8 parts of shell.
3. a kind of Chinese medicine composition treating chronic superficial gastritiss according to claim 1 it is characterised in that: described flower
Green pepper is 8 parts, 5 parts of Semen Coiciss, 11 parts of Tremella, 8 parts of Fructus Piperis Longi, 9 parts of Fructus Anisi Stellati, 5 parts of Fructus Crataegi cuneatae, 8 parts of Fructus Citri Sarcodactylis, 5 parts of Rhizoma Alpiniae Officinarum, trifoliate orange
7 parts of shell.
4. a kind of Chinese medicine composition treating chronic superficial gastritiss according to claim 1 it is characterised in that: described flower
Green pepper is 5 parts, 7 parts of Semen Coiciss, 13 parts of Tremella, 6 parts of Fructus Piperis Longi, 10 parts of Fructus Anisi Stellati, 4 parts of Fructus Crataegi cuneatae, 9 parts of Fructus Citri Sarcodactylis, 9 parts of Rhizoma Alpiniae Officinarum,
11 parts of Fructus Aurantii.
5. a kind of Chinese medicine composition treating chronic superficial gastritiss according to any one of claim 1 ~ 4, its feature exists
In: described Fructus Citri Sarcodactylis are gold bergamot.
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