CN106310189A - Traditional Chinese medicine preparation for treating poultry diarrhea and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating poultry diarrhea and preparation method thereof Download PDF

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CN106310189A
CN106310189A CN201610827789.7A CN201610827789A CN106310189A CN 106310189 A CN106310189 A CN 106310189A CN 201610827789 A CN201610827789 A CN 201610827789A CN 106310189 A CN106310189 A CN 106310189A
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parts
rhizoma
radix
fructus
chinese medicine
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邓新平
聂雄
黄庭宝
傅小妮
李小周
卢煜海
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Guangxi University
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Guangxi University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
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    • A61K36/11Pteridophyta or Filicophyta (ferns)
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Abstract

The invention belongs to the technical field of research and development of traditional Chinese medicine preparations and particularly relates to a traditional Chinese medicine preparation for treating poultry diarrhea and a preparation method thereof. The traditional Chinese medicine preparation for treating poultry diarrhea is made from, by weight, 15-25 parts of Rhizoma Cyrtomii Fortunei, 20-30 parts of Herba Agrimoniae, 20-30 parts of Fructus Mume, 5-9 parts of Radix Dichroae, 5-15 parts of Fructus Gardeniae, 5-15 parts of Radix et Rhizoma Rhei, 5-13 parts of Caulis Akebiae, 5-20 parts of Fructus Chebulae, 9-18 parts of Radix Curcumae, 10-18 parts of Radix Glycyrrhizae Preparata, 15-20 parts of Radix Bupleuri, 15-25 parts of Rhizoma Cimicifugae, 20-25 parts of Rhizoma Atractylodis, 12-18 parts of Rhizoma Zingiberis Preparata, 10-20 parts of Fructus Hordei Germinatus, 10-20 parts of Massa Medicata Fermentata, 6-12 parts of Fructus Crataegi, 15-20 parts of Rhizoma Atractylodis Macrocephalae, and 15-20 parts of Herba Plantaginis. The traditional Chinese medicine preparation for treating poultry diarrhea is effective in strengthening the spleen and stomach, converging for detoxifying, activating blood to remove wind and promoting digestion, and has significant effect in stopping diarrhea, restoring gastric and intestinal functions and maintaining normal function of digestive system; the traditional Chinese medicine preparation is simple in composition, low in cost, short in treatment time and specially effective in treating poultry diarrhea.

Description

A kind of Chinese medicine preparation treating avian dysentery and preparation method thereof
Technical field
The invention belongs to Chinese medicine preparation research and development technology field, particularly to a kind of Chinese medicine preparation treating avian dysentery and Preparation method.
Background technology
In the various diseases of poultry, genus shigella, diarrhoea are the most universal.Avian dysentery mainly includes by antibacterial, virus, posts The general name of the infested symptom of diarrhea waiting various factors to cause.The most serious dysentery, can lose large quantity of moisture, salt and basic species , there is dehydration, salt deficiency and acidosis in various degree in matter, blood thickens contracting, thus affects the normal circulation of body fluid, finally causes Heart failure causes death.The least sickness rate of poultry age in days is the highest, and case fatality rate is the highest, between generally 10-40%.Primary disease is One of principal disease of harm poultry farming.
At present, the common medicine for the treatment of avian dysentery has: enemy is grown sturdily only, dysentery rattan is clean, the rolling of furazolidone, fluorine is made, celebrating increasing peace, dysentery mattress gram Star is peaceful with meaning Hakuri mutually.Said medicine only has the anti-mattress of simple antiinflammatory, dysentery relieving effect, and curative effect is the highest, and can carry toward contact Coming Drug resistance, drug-resistant capability effect, in poultry farming, the specific drug of Chang Yinwu treatment avian dysentery causes large stretch of poultry dead.
Therefore, in the animal husbandry of poultry, it is sought after that a kind of good effect, treatment time be short, the treatment poultry dysentery of low cost The medicine of disease.
The information being disclosed in this background section is merely intended to increase the understanding of the general background to the present invention, and should not When being considered to recognize or imply in any form this information structure prior art well known to persons skilled in the art.
Summary of the invention
For above-mentioned deficiency present in prior art, the present invention provide a kind of Chinese medicine preparation treating avian dysentery and Preparation method, this Chinese medicine composition reasonable recipe, preparation are simply, effect is obvious, have no side effect, have no drug resistance and medicine is residual Stay, can effectively treat avian dysentery.
To achieve these goals, the present invention is to realize by the following technical solutions:
A kind of Chinese medicine preparation treating avian dysentery, is made up of following components by weight: Rhizoma Osmundae 15-25 part, Herba Agrimoniae 20-30 part, Fructus Mume 20-30 part, Radix Dichroae 5-9 part, Yellow Fructus Gardeniae 5-15 part, Radix Et Rhizoma Rhei 5-15 part, Caulis Akebiae 5-13 part, Fructus Chebulae 5-20 part, Radix Curcumae 9-18 part, Radix Glycyrrhizae Preparata 10-18 part, Radix Bupleuri 15-20 part, Rhizoma Cimicifugae 15-25 part, Rhizoma Atractylodis 20-25 part, Rhizoma Zingiberis Preparatum 12-18 part, Fructus Hordei Germinatus 10-20 part, Massa Medicata Fermentata 10-20 part, Fructus Crataegi 6-12 part, Rhizoma Atractylodis Macrocephalae 15-20 part and Herba Plantaginis 15-20 part.
As preferably, the Chinese medicine preparation of described treatment avian dysentery, it is made up of following components by weight: Rhizoma Osmundae 20 Part, Herba Agrimoniae 26 parts, Fructus Mume 22 parts, Radix Dichroae 8 parts, Yellow Fructus Gardeniae 12 parts, Radix Et Rhizoma Rhei 13 parts, Caulis Akebiae 10 parts, Fructus Chebulae 10 parts, Radix Curcumae 12 Part, Radix Glycyrrhizae Preparata 15 parts, Radix Bupleuri 16 parts, Rhizoma Cimicifugae 20 parts, Rhizoma Atractylodis 22 parts, Rhizoma Zingiberis Preparatum 15 parts, 15 parts of Fructus Hordei Germinatus, Massa Medicata Fermentata 15 parts, Fructus Crataegi 10 parts, The Rhizoma Atractylodis Macrocephalae 18 parts and Herba Plantaginis 18 parts.
It addition, present invention also offers the preparation method of the Chinese medicine preparation of described treatment avian dysentery, including following step Rapid:
(1) weigh by weight the Rhizoma Osmundae in formula, Herba Agrimoniae, Fructus Mume, Radix Dichroae, Yellow Fructus Gardeniae, Radix Et Rhizoma Rhei, Caulis Akebiae, Fructus Chebulae, Radix Curcumae, Radix Glycyrrhizae Preparata, Radix Bupleuri, Rhizoma Cimicifugae, Rhizoma Atractylodis, Rhizoma Zingiberis Preparatum, Fructus Hordei Germinatus, Massa Medicata Fermentata, Fructus Crataegi, the Rhizoma Atractylodis Macrocephalae, Herba Plantaginis, clean and dry, by pulverizing After machine is pulverized and mixed, adds suitable quantity of water elder generation intense fire and boil slow fire again and boil in a covered pot over a slow fire 1.5-2.0h, after filtration first filtrate, medicinal residues are repeated force Fire boils that slow fire is stewing operates second time equally again, is concentrated to give herb liquid study after merging filtrate;
(2) in the herb liquid study of step (1) gained, add the dehydrated alcohol of its volume 2-6 times, stirring and dissolving, Reflux at a temperature of 85-95 DEG C 2.5-3.5h, obtains refined herb liquid;
(3) take the refined herb liquid of step (2) gained, after decompression recycling ethanol, by herb liquid low-temperature evaporation, obtain latex shape Chinese medicine material, puts into glue milky substance drying machine and is dried, and inlet temperature is 130-160 DEG C, and leaving air temp is 75-90 DEG C, Obtaining powdered rubber, powder is broken to 120 mesh, stirs, and must treat the Chinese medicine preparation of avian dysentery.
Compared with prior art, there is advantages that
(1) Chinese medicine preparation of the treatment avian dysentery of the present invention has strengthening the spleen and stomach, convergence removing toxic substances, promoting blood circulation by removing wind, digestion promoting Effect, particularly dysentery relieving, recover gastrointestinal function and maintain normal stool systemic-function effect notable.
(2) Chinese medicine preparation of the treatment avian dysentery of the present invention, formula combination is simple, and low cost, treatment time is short, to controlling Treat avian dysentery and have specially good effect.
(3) raw material of the Chinese medicine preparation of the treatment avian dysentery of the present invention is pure natural raw material, without any chemical classes Medicine, preparation method is simple, uses this Chinese medicine composition poultry meat mass-energy to reach nuisanceless requirement, the body of people has been effectively ensured Body is healthy, can promote the use of.
Detailed description of the invention
Below in conjunction with specific embodiment, the detailed description of the invention of the present invention is described in detail, it is to be understood that the present invention Protection domain do not limited by detailed description of the invention.
Embodiment 1:
A kind of Chinese medicine preparation treating avian dysentery, is made up of following components by weight: Rhizoma Osmundae 15 parts, Herba Agrimoniae 20 Part, Fructus Mume 20 parts, Radix Dichroae 5 parts, Yellow Fructus Gardeniae 5 parts, Radix Et Rhizoma Rhei 5 parts, Caulis Akebiae 5 parts, Fructus Chebulae 5 parts, Radix Curcumae 9 parts, Radix Glycyrrhizae Preparata 10 parts, Radix Bupleuri 15 parts, Rhizoma Cimicifugae 15 parts, Rhizoma Atractylodis 20 parts, Rhizoma Zingiberis Preparatum 12 parts, 10 parts of Fructus Hordei Germinatus, Massa Medicata Fermentata 10 parts, Fructus Crataegi 6 parts, the Rhizoma Atractylodis Macrocephalae 15 parts and Herba Plantaginis 15 Part.
The preparation method of the Chinese medicine preparation of described treatment avian dysentery, comprises the following steps:
(1) weigh by weight the Rhizoma Osmundae in formula, Herba Agrimoniae, Fructus Mume, Radix Dichroae, Yellow Fructus Gardeniae, Radix Et Rhizoma Rhei, Caulis Akebiae, Fructus Chebulae, Radix Curcumae, Radix Glycyrrhizae Preparata, Radix Bupleuri, Rhizoma Cimicifugae, Rhizoma Atractylodis, Rhizoma Zingiberis Preparatum, Fructus Hordei Germinatus, Massa Medicata Fermentata, Fructus Crataegi, the Rhizoma Atractylodis Macrocephalae, Herba Plantaginis, clean and dry, by pulverizing After machine is pulverized and mixed, adds suitable quantity of water elder generation intense fire and boil slow fire again and boil in a covered pot over a slow fire 1.5h, after filtration first filtrate, medicinal residues are repeated intense fire and boil The slow fire that boils again is stewing operates second time equally, is concentrated to give herb liquid study after merging filtrate;
(2) adding the dehydrated alcohol of its volume 2 times in the herb liquid study of step (1) gained, stirring and dissolving, at 85 DEG C At a temperature of reflux 2.5h, obtain refined herb liquid;
(3) take the refined herb liquid of step (2) gained, after decompression recycling ethanol, by herb liquid low-temperature evaporation, obtain latex shape Chinese medicine material, puts into glue milky substance drying machine and is dried, and inlet temperature is 130 DEG C, and leaving air temp is 75 DEG C, obtains powder Material, powder is broken to 120 mesh, stirs, and must treat the Chinese medicine preparation of avian dysentery.
Embodiment 2:
A kind of Chinese medicine preparation treating avian dysentery, is made up of following components by weight: Rhizoma Osmundae 25 parts, Herba Agrimoniae 30 Part, Fructus Mume 30 parts, Radix Dichroae 9 parts, Yellow Fructus Gardeniae 15 parts, Radix Et Rhizoma Rhei 15 parts, Caulis Akebiae 13 parts, Fructus Chebulae 20 parts, Radix Curcumae 18 parts, Radix Glycyrrhizae Preparata 18 Part, Radix Bupleuri 20 parts, Rhizoma Cimicifugae 25 parts, Rhizoma Atractylodis 25 parts, Rhizoma Zingiberis Preparatum 18 parts, 20 parts of Fructus Hordei Germinatus, Massa Medicata Fermentata 20 parts, Fructus Crataegi 12 parts, the Rhizoma Atractylodis Macrocephalae 20 parts and Herba Plantaginis 20 parts.
The preparation method of the Chinese medicine preparation of described treatment avian dysentery, comprises the following steps:
(1) weigh by weight the Rhizoma Osmundae in formula, Herba Agrimoniae, Fructus Mume, Radix Dichroae, Yellow Fructus Gardeniae, Radix Et Rhizoma Rhei, Caulis Akebiae, Fructus Chebulae, Radix Curcumae, Radix Glycyrrhizae Preparata, Radix Bupleuri, Rhizoma Cimicifugae, Rhizoma Atractylodis, Rhizoma Zingiberis Preparatum, Fructus Hordei Germinatus, Massa Medicata Fermentata, Fructus Crataegi, the Rhizoma Atractylodis Macrocephalae, Herba Plantaginis, clean and dry, by pulverizing After machine is pulverized and mixed, adds suitable quantity of water elder generation intense fire and boil slow fire again and boil in a covered pot over a slow fire 2.0h, after filtration first filtrate, medicinal residues are repeated intense fire and boil The slow fire that boils again is stewing operates second time equally, is concentrated to give herb liquid study after merging filtrate;
(2) adding the dehydrated alcohol of its volume 6 times in the herb liquid study of step (1) gained, stirring and dissolving, at 95 DEG C At a temperature of reflux 3.5h, obtain refined herb liquid;
(3) take the refined herb liquid of step (2) gained, after decompression recycling ethanol, by herb liquid low-temperature evaporation, obtain latex shape Chinese medicine material, puts into glue milky substance drying machine and is dried, and inlet temperature is 160 DEG C, and leaving air temp is 90 DEG C, obtains powder Material, powder is broken to 120 mesh, stirs, and must treat the Chinese medicine preparation of avian dysentery.
Embodiment 3:
A kind of Chinese medicine preparation treating avian dysentery, is made up of following components by weight: Rhizoma Osmundae 20 parts, Herba Agrimoniae 25 Part, Fructus Mume 25 parts, Radix Dichroae 7 parts, Yellow Fructus Gardeniae 10 parts, Radix Et Rhizoma Rhei 10 parts, Caulis Akebiae 10 parts, Fructus Chebulae 10 parts, Radix Curcumae 12 parts, Radix Glycyrrhizae Preparata 12 Part, Radix Bupleuri 18 parts, Rhizoma Cimicifugae 20 parts, Rhizoma Atractylodis 22 parts, Rhizoma Zingiberis Preparatum 15 parts, 15 parts of Fructus Hordei Germinatus, Massa Medicata Fermentata 15 parts, Fructus Crataegi 10 parts, the Rhizoma Atractylodis Macrocephalae 18 parts and Herba Plantaginis 18 parts.
The preparation method of the Chinese medicine preparation of described treatment avian dysentery, comprises the following steps:
(1) weigh by weight the Rhizoma Osmundae in formula, Herba Agrimoniae, Fructus Mume, Radix Dichroae, Yellow Fructus Gardeniae, Radix Et Rhizoma Rhei, Caulis Akebiae, Fructus Chebulae, Radix Curcumae, Radix Glycyrrhizae Preparata, Radix Bupleuri, Rhizoma Cimicifugae, Rhizoma Atractylodis, Rhizoma Zingiberis Preparatum, Fructus Hordei Germinatus, Massa Medicata Fermentata, Fructus Crataegi, the Rhizoma Atractylodis Macrocephalae, Herba Plantaginis, clean and dry, by pulverizing After machine is pulverized and mixed, adds suitable quantity of water elder generation intense fire and boil slow fire again and boil in a covered pot over a slow fire 1.8h, after filtration first filtrate, medicinal residues are repeated intense fire and boil The slow fire that boils again is stewing operates second time equally, is concentrated to give herb liquid study after merging filtrate;
(2) adding the dehydrated alcohol of its volume 4 times in the herb liquid study of step (1) gained, stirring and dissolving, at 90 DEG C At a temperature of reflux 3.0h, obtain refined herb liquid;
(3) take the refined herb liquid of step (2) gained, after decompression recycling ethanol, by herb liquid low-temperature evaporation, obtain latex shape Chinese medicine material, puts into glue milky substance drying machine and is dried, and inlet temperature is 150 DEG C, and leaving air temp is 80 DEG C, obtains powder Material, powder is broken to 120 mesh, stirs, and must treat the Chinese medicine preparation of avian dysentery.
Embodiment 4: the Chinese medicine preparation of the treatment avian dysentery of the present invention is at the test effect of preventing and treating avian dysentery
As a example by the duck dysentery that this clinical trial is only relatively common in treatment avian dysentery, application is river in Guangxi, Nanning City Duckery of peaceful district.
Yongning District, Nanning City duckery raises on limit, fish pond nearly 2000 ducks, and 60 ages in days, body weight are at 1.5-1.8kg. On July 25th, 2015, most of duck group crawled on the ground, to scavenge the most as usual, and stool is all in water sample and speckle with viscous Liquid, Laboratory Diagnosed is duck dysentery.Then from duckery, isolate 500 ducks to test, 500 ducks be randomly divided into 4 groups, Matched group and 3 experimental grouies, often group 125.The treatment of preparation in experimental group 1,2, the 3 feeding embodiment of the present invention 1,2,3 respectively The Chinese medicine preparation of avian dysentery, matched group feeding oxytetracycline.
Usage and dosage: the every 100g of Chinese medicine preparation, spice 250kg that treat avian dysentery by the present invention feed or drink water 400kg, every day 2-3 time, is used in conjunction 3-5 day, reaches to treat the purpose of disease by gastrointestinal absorption after being administered orally.Each medicine feed organizing duck Number of times, dosage, medicine feed time are the most identical.
Duck dysentery efficacy assessment standard:
Recovery from illness: spirit is normal, drinking-water of searching for food is normal, and feces is normal, and feather is normal, breathes normal, and bouncing cuts open inspection liver Dirty, hearts etc. are normal, and test in laboratory has no S. pullonum etc.;
Being clearly better: spirit has taken a turn for the better, drinking-water of searching for food has taken a turn for the better, but recovers normal the most completely, and feces has Normally, but the most still there are some abnormal;
Have no improvement: clinical symptoms does not has any improvement.
Observe and record the test effect situation of 4 groups of ducks, as shown in table 1.
The Chinese medicine preparation of the treatment avian dysentery of table 1 present invention is at the test effect of preventing and treating avian dysentery
From table 1 it follows that this clinical test results statistical analysis, Chinese medicine preparation experimental group of the present invention with compare It is extremely notable (P < 0.01) that group compares difference in terms of cure rate, hence it is evident that is better than comparison.
The aforementioned description to the specific illustrative embodiment of the present invention illustrates that and the purpose of illustration.These describe It is not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to above-mentioned teaching, can much change And change.The purpose selected exemplary embodiment and describe is to explain that the certain principles of the present invention and reality thereof should With so that those skilled in the art be capable of and utilize the present invention various different exemplary and Various different selections and change.The scope of the present invention is intended to be limited by claims and equivalents thereof.

Claims (3)

1. the Chinese medicine preparation treating avian dysentery, it is characterised in that be made up of following components by weight: Rhizoma Osmundae 15-25 Part, Herba Agrimoniae 20-30 part, Fructus Mume 20-30 part, Radix Dichroae 5-9 part, Yellow Fructus Gardeniae 5-15 part, Radix Et Rhizoma Rhei 5-15 part, Caulis Akebiae 5-13 part, Ke Sub-5-20 part, Radix Curcumae 9-18 part, Radix Glycyrrhizae Preparata 10-18 part, Radix Bupleuri 15-20 part, Rhizoma Cimicifugae 15-25 part, Rhizoma Atractylodis 20-25 part, Rhizoma Zingiberis Preparatum 12- 18 parts, Fructus Hordei Germinatus 10-20 part, Massa Medicata Fermentata 10-20 part, Fructus Crataegi 6-12 part, Rhizoma Atractylodis Macrocephalae 15-20 part and Herba Plantaginis 15-20 part.
The Chinese medicine preparation for the treatment of avian dysentery the most according to claim 1, it is characterised in that by weight by following components Make: Rhizoma Osmundae 20 parts, Herba Agrimoniae 26 parts, Fructus Mume 22 parts, Radix Dichroae 8 parts, Yellow Fructus Gardeniae 12 parts, Radix Et Rhizoma Rhei 13 parts, Caulis Akebiae 10 parts, Fructus Chebulae 10 Part, Radix Curcumae 12 parts, Radix Glycyrrhizae Preparata 15 parts, Radix Bupleuri 16 parts, Rhizoma Cimicifugae 20 parts, Rhizoma Atractylodis 22 parts, Rhizoma Zingiberis Preparatum 15 parts, 15 parts of Fructus Hordei Germinatus, Massa Medicata Fermentata 15 parts, Fructus Crataegi 10 parts, the Rhizoma Atractylodis Macrocephalae 18 parts and Herba Plantaginis 18 parts.
The preparation method of the Chinese medicine preparation for the treatment of avian dysentery the most according to claim 1 and 2, it is characterised in that include Following steps:
(1) Rhizoma Osmundae in formula, Herba Agrimoniae, Fructus Mume, Radix Dichroae, Yellow Fructus Gardeniae, Radix Et Rhizoma Rhei, Caulis Akebiae, Fructus Chebulae, strongly fragrant is weighed by weight Gold, Radix Glycyrrhizae Preparata, Radix Bupleuri, Rhizoma Cimicifugae, Rhizoma Atractylodis, Rhizoma Zingiberis Preparatum, Fructus Hordei Germinatus, Massa Medicata Fermentata, Fructus Crataegi, the Rhizoma Atractylodis Macrocephalae, Herba Plantaginis, clean and dry, pass through pulverizer After being pulverized and mixed, add suitable quantity of water elder generation intense fire and boil slow fire again and boil in a covered pot over a slow fire 1.5-2.0h, after filtration first filtrate, medicinal residues are repeated intense fire Boil again that slow fire is stewing operates second time equally, after merging filtrate, be concentrated to give herb liquid study;
(2) adding the dehydrated alcohol of its volume 2-6 times in the herb liquid study of step (1) gained, stirring and dissolving, at 85-95 Reflux at a temperature of DEG C 2.5-3.5h, obtains refined herb liquid;
(3) take the refined herb liquid of step (2) gained, after decompression recycling ethanol, by herb liquid low-temperature evaporation, obtain latex shape Chinese medicine Material, puts into glue milky substance drying machine and is dried, and inlet temperature is 130-160 DEG C, and leaving air temp is 75-90 DEG C, obtains Powdered rubber, powder is broken to 120 mesh, stirs, and must treat the Chinese medicine preparation of avian dysentery.
CN201610827789.7A 2016-09-18 2016-09-18 Traditional Chinese medicine preparation for treating poultry diarrhea and preparation method thereof Pending CN106310189A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1559520A (en) * 2004-02-24 2005-01-05 江苏天成保健品有限公司 Chinese medicinal preparation for preventing and curing enteric disease of animal and paultory and its preparation method
CN102772598A (en) * 2012-08-20 2012-11-14 解连新 Traditional Chinese medicine for treating bacillary dysentery
CN104383081A (en) * 2014-12-05 2015-03-04 河南科技学院 Traditional Chinese medicine preparation for treating pig diarrhea

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1559520A (en) * 2004-02-24 2005-01-05 江苏天成保健品有限公司 Chinese medicinal preparation for preventing and curing enteric disease of animal and paultory and its preparation method
CN102772598A (en) * 2012-08-20 2012-11-14 解连新 Traditional Chinese medicine for treating bacillary dysentery
CN104383081A (en) * 2014-12-05 2015-03-04 河南科技学院 Traditional Chinese medicine preparation for treating pig diarrhea

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