CN106309659A - Acupoint plaster for hypertension - Google Patents
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Abstract
The invention discloses an acupoint plaster for hypertension, and aims to reduce or stop taking the antihypertensive and keep the blood pressure stable, thereby implementing convenient and effective treatment on hypertension. The acupoint plaster for hypertension is composed of the following traditional Chinese medicinal materials: panicled swallowwort root, motherwort, fructus evodiae, folium artemisiae argyi, herba schizonepetae and white pepper. Compared with the treatment means in the prior art, the acupoint plaster for hypertension is used for treating hypertension by externally applying traditional Chinese medicines and stimulating the acupoints, does not need to take the medicine or injection, and can keep the blood pressure stable for along time after reducing or stopping taking the antihypertensive. The effective rate for primary and secondary hypertension is 90.2%. After the treatment of one course of treatment (four months), 83.8% of the patients do not take the antihypertensive any longer.
Description
Technical field
The present invention relates to a kind of Chinese medicine, the external plaster of a kind of Hypertension.
Background technology
Hypertension Digital arteries shrinks pressure and (or) diastolic pressure raises, and is often accompanied by the organ dysfunctions such as the heart, brain, kidney and retina
Property or the organic systemic disease changing into feature.Its prevalence is in rising trend, and current prevalence has reached 24.5%.Impact
The principal element of hypertension is the hematodinamics parameters such as left stroke volume, peripheral vascular resistance, therefore all can directly or indirectly affect
Cardiac output or the factor of increase Peripheral resistance, lead to blood pressure and raise.
The hyperpietic cause of disease is not yet fully apparent from by doctor trained in Western medicine, but nature-nurture factor can make its prevalence liter
High.Inherited genetic factors determines individual susceptibility, and the long-term accumulated of environmental factors not only can promote genetic predisposition to show, Er Qieke
Change inherited character to a certain extent.High salt diet, lack motion, nervous, fat etc. be all the important environment of hypertension
Risk factor.Lacking motion is to cause body obesity, insulin resistant, blood fat disorder, suffer from the important of hypertension and heart disease
Factor.The normal arterial pressure individuality that sitting is moved less is than the danger of more active and healthy age-matched control group generation hypertension
Increase by 20% 50%.Lacking regular physical exertion, Condition of Cardiovascular Function is low, muscle power poor resistance, and muscle power toleration is more
Difference, Prevalence of Hypertension is the highest.Additionally, ethanol, socio-psychological factors includes structure of society, political position, economic condition, occupation
The division of labor, living condition etc..Regular nervous and various burden stress, make cerebral cortex vasomotor center irritability increase
Height, catecholamine release increases, and causes blood pressure to raise, and solid by activating feritin, also referred to as Angiotensinogenase aldehyde
Ketone system promotes sodium retention.Some character trait anxiety, fear, indignation, depression etc. all can make blood pressure raise.
Prior art Hypertension, still based on Western medicine, need to have been taken medicine " well-known " throughout one's life.Depressor toxicity is very
Greatly, in the course of time, the biggest negative effect will be brought to the quality of life of patient.
Summary of the invention
It is an object of the invention to provide a kind of hypertension point-application plaster, will solve the technical problem that it is to reduce or not
Need take depressor and keep blood pressure stabilization, convenient, effective Hypertension.
A kind of hypertension point-application plaster, often patch plaster includes the following quality Chinese crude drug than component: Radix Cynanchi Paniculati
0.1 0.3, Herba Leonuri 0.1 0.4, Evodia rutaecarpa 0.1 0.3, Folium Artemisiae Argyi 0.1 0.3, Herba Schizonepetae 0.1 0.3, Radix orixae japonicae 0.05 0.2.
Often patch plaster of the present invention contains 0.05 0.1 mass Moschus than component.
Often patch plaster of the present invention includes the following quality Chinese crude drug than component: Radix Cynanchi Paniculati 0.1 0.15, Herba Leonuri
0.1 0.15, Evodia rutaecarpa 0.1 0.17, Folium Artemisiae Argyi 0.08 0.12, Herba Schizonepetae 0.08 0.12, Radix orixae japonicae 0.025 0.082.The present invention
Described often patch plaster contains 0.06 0.09 mass Moschus than component.
Often patch plaster of the present invention includes the following quality Chinese crude drug than component: Radix Cynanchi Paniculati 0.12 0.14, Herba Leonuri
0.12 0.14, Evodia rutaecarpa 0.12 0.14, Folium Artemisiae Argyi 0.1 0.11, Herba Schizonepetae 0.1 0.11, Radix orixae japonicae 0.04 0.08.Institute of the present invention
State often patch plaster to be made up of than the Chinese crude drug of component following quality: Radix Cynanchi Paniculati 0.14, Herba Leonuri 0.15, Evodia rutaecarpa 0.13, Folium Artemisiae Argyi
0.1, Herba Schizonepetae 0.1, Radix orixae japonicae 0.082.
The preparation method of hypertension point-application plaster of the present invention is that described Chinese crude drug is ground into Chinese medicine powder, in
Medicated powder >=100 mesh, then according to 60 65% substrate and 35 40% Chinese medicine powders are mixed by mass percent, described substrate is hot melt
Glue, adds Chinese medicine powder mix homogeneously and makes medicated core, then use and spread onto on medical proof fabric, obtain plaster after heat of solution melten gel,
Every piece of plaster adhesive plaster area is 6 × 6cm2, a diameter of 3.5cm of medicated core.In plaster of the present invention, use 61 63% substrate and
37 39% Chinese medicine powder mixing.
Hypertension point-application plaster of the present invention, it is characterised in that: in described plaster, use 62% substrate and
38% Chinese medicine powder mixing.
The hypertension point-application plaster of the present invention, compared with prior art treatment means, uses and sticks stimulation outside Chinese medicine
Acupoint therapy hypertension, do not take medicine, do not have an injection, reduce take or withdraw depressor after blood pressure can be kept steady in a long-term, to I,
II phase hypertension effective percentage 90.2%, through the treatment of four months course for the treatment of, the patient of 83.8% is not taking depressor.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail.The quality ratio of the present invention is in component, with gram for single
Position.
The hypertension point-application plaster of the present invention, for Hypertension disease.
Often in patch plaster, it is made up of than the Chinese crude drug of component following quality:
Radix Cynanchi Paniculati 0.1 0.3, Herba Leonuri 0.1 0.4, Evodia rutaecarpa 0.1 0.3, Folium Artemisiae Argyi 0.1 0.3, Herba Schizonepetae 0.1 0.3, white
Fructus Piperis 0.05 0.2, Moschus 0.05 0.1.
Further, often in patch plaster, the preferred quality of Chinese crude drug than component is:
Radix Cynanchi Paniculati 0.1 0.15, Herba Leonuri 0.1 0.15, Evodia rutaecarpa 0.1 0.17, Folium Artemisiae Argyi 0.08 0.12, Herba Schizonepetae 0.08
0.12, Radix orixae japonicae 0.025 0.082.
Further, often in patch plaster, preferred Moschus quality is 0.06 0.09 than component.
Often in patch plaster, the preferred quality of Chinese crude drug than component is:
Radix Cynanchi Paniculati 0.12 0.14, Herba Leonuri 0.12 0.14, Evodia rutaecarpa 0.12 0.14, Folium Artemisiae Argyi 0.1 0.11, Herba Schizonepetae 0.1
0.11, Radix orixae japonicae 0.04 0.08.
Often in patch plaster, optimal quality consists of than the Chinese crude drug of component:
Radix Cynanchi Paniculati 0.14, Herba Leonuri 0.15, Evodia rutaecarpa 0.13, Folium Artemisiae Argyi 0.1, Herba Schizonepetae 0.1, Radix orixae japonicae 0.082.
In the hypertension point-application plaster of the present invention, effect of each taste Chinese crude drug used and acting as:
Radix Cynanchi Paniculati, acrid in the mouth, temperature, nontoxic.Effect: analgesia, cough-relieving, inducing diuresis to remove edema, promoting blood circulation and detoxication.Coronary blood flow can be increased
Amount, improves myocardial metabolism, thus alleviates myocardial ischemia.Herb contains paeonol about 1%, and paeonol has hypotensive activity, and
In addition to paeonol, Radix Cynanchi Paniculati is possibly together with other antihypertensive compositions, and (water boiling concentration adds ethanol to mouse peritoneal injection Radix Cynanchi Paniculati extracting solution
Remove precipitation person, wherein without paeonol), spontaneous activity can be substantially reduced, but do not extend the length of one's sleep of barbiturates, also
Having an analgesic activity (hot plate method), above-mentioned preparation also can reduce the blood pressure of Canis familiaris L., rabbit and rat.Radix Cynanchi Paniculati also has dispelling wind for relieving itching, resists
Allergy effect.
Herba Leonuri, the micro-hardship of acrid in the mouth, cool, enter pericardium, Liver Channel.Effect: blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema.Energy coronary artery dilating, significantly
Increase coronary flow and cardiac muscle nutritional blood flow and have hypotensive activity.Herba Leonuri water logging agent, leonurine, leonurine first
The Total alkaloids animals iv injection to anesthesia, all has hypotensive effect.
Evodia rutaecarpa, arduous, temperature, poisonous, enter liver, stomach warp.Effect: warming middle-JIAO, pain relieving, to regulate the flow of vital energy, dampness, stopping vomiting, against acid regurgitation, is fainted
Cloudy headache, coldness of ZANG-organ vomiting and diarrhoea, abdominal distention, tinea pedis, hernia, aphthous ulcer, toothache, eczema, impetigo.Energy let the fire back to its origin, hence it is evident that
Reduce blood pressure, there is obvious analgesic activity simultaneously.About the method for Fructus Evodiae Hypertension in clinical report: by Fructus Evodiae
Grind into powder, take 0.6～1 liang every time, dress the two foot hearts (applying before liking to sleep most, wrap up with cloth) with vinegar.Blood after general deposited 12～24 hours
Pressure begins to decline, and subjective symptoms alleviates.Mild applies 1 time, and applying of weight i.e. shows antihypertensive effect 2～3 times.
Folium Artemisiae Argyi, toil, temperature, enter spleen, liver, kidney channel.Effect: blood of regulating the flow of vital energy, dispels cold wet；Warming the meridian, hemostasis, antiabortive.Control trusted subordinate cold
Bitterly, convulsion of having loose bowels, chronic dysentery, tell nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.Can antibacterial, expansion
Blood vessel, excited suction." modern Practical Chinese medicinal " (page 535, June in 1999 the 1st edition, People's Health Publisher) to Folium Artemisiae Argyi
Recording, pharmacological research the 5th selects: decoct can excited isolated uterine, suppress intestine in vitro, isolated frog heart, 20mg/kg is administered, then can
Excited breathing, reduces blood pressure.Clinical practice the 4th point: scrotal pruritus, with Folium Artemisiae Argyi, each 30g of Herba Senecionis Scandentis, adds water after dense decocting, and bath is washed
10 15 minutes, affected part, every day 1 time, 10 times was 1 course for the treatment of, avoids local to scratch and soap, hot water are cleaned during treatment.Controlled 20
In example, the short person of the course of disease 3 months, elder 32 years, in addition to 2 examples are invalid, remaining skin lesion, pruritus all eliminate.Visible, Folium Artemisiae Argyi has antipruritic
Anti-allergic effects.
Herba Schizonepetae, temperature, acrid in the mouth is bitter, enters lung, Liver Channel.Effect: deliver, dispels the wind, treating blood disorders；Parch to black stops blooding.Cure cold heating, head
Bitterly, laryngopharynx swelling and pain, apoplexy locked mouth, spit blood, epistaxis, have blood in stool；Metrorrhagia, puerperal blood faints；Carbuncle, skin ulcer scabies, scrofula.There is antibacterial, solution
Heat, dispel the wind, rash, antianaphylactic effect.About the record of Herba Schizonepetae anti-allergic effects, " modern Practical Chinese medicinal " (page 62,
June in 1999 the 1st edition, People's Health Publisher) record: Herba Schizonepetae, modern report the 1st point: urticaria and skin pruritus, take
Clean Herba Schizonepetae 30g, grinds to the powder, and loads in gauze bag, uniformly dispense affected part, then rub back and forth to trouble with palm after sieving
Place's heating is degree.Treatment acute urticaria and all skin prurituss, the lighter 12 times, severe one 24 times.Equally, Herba Schizonepetae has
Control the effect of skin pruritus.
Radix orixae japonicae, pungent, heat, enter stomach, large intestine channel.Effect: warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, expectorant, removing toxic substances.Controlling cold-phlegm food stagnation, gastral cavity abdomen is cold
Bitterly, regurgitation, vomit clear water, have loose bowels, cold-dysentery.And solve bromatotoxin.Radix orixae japonicae external has warm excitement to skin, can play thorn
Swash the effect at acupuncture point.
Moschus, property is pungent, temperature, enters the heart, spleen, Liver Channel.Effect: have one's ideas straightened out, wards off dirty, dredging collateral, dissipating blood stasis.Controlling apoplexy, syncope due to accumulation of phlegm, attacked by pestiferous factors is tired of
Vexed, trusted subordinate's sudden pain, traumatic injury, swollen ulcer drug.
A few taste medicines share the skin surface at acupuncture point and stick and play hypotensive effect.Radix Cynanchi Paniculati, Herba Leonuri can increase coronary blood
Flow and cardiac muscle nutritional blood flow, improve myocardial metabolism, alleviate myocardial ischemia, coordinate Folium Artemisiae Argyi to use and can expand blood vessel, emerging
Put forth energy to breathe；Evodia rutaecarpa pain relieving, regulate the flow of vital energy, can let the fire back to its origin, there is sedation；Herba Schizonepetae is delivered, and dispels the wind, treating blood disorders, has strong work
With；Radix orixae japonicae external has warm excitement to skin, can play the effect of stimulating acupoint.A few taste medicines share stick on acupuncture point can
The negative and positive making body tend to balance, QI and blood punching and, make blood pressure drops, play the effect of Hypertension.
Effect after the combination of a few taste medicines:
(1) acupuncture point is acted as a spur.Stimulation to acupuncture point plays an important role to treating this disease.External application stimulating acupoint, with
Effect equivalent of acupuncture.This therapy plays hypotensive effect by sticking of skin zone." Plain Questions, skin zone's opinion " is said: the beginning of all kinds of diseases and ailments is raw also,
Must be prior to fur.Evil visitor, in skin then opening of sweat pores, opens, and heresy enters visitor in channels, and channels is the most then noted in passages through which vital energy circulates, passages through which vital energy circulates the most then enter to give up in
Internal organs are also.In modern medicine, body surface internal organs are correlated with the foundation of theory, are all can to reflect theory and the reality of splanchnopathy with skin zone
Trample inseparable.Twelve skin region application treatment hypertension, three effects and four greatly that can produce are reacted greatly.
Three effects greatly: excitation, sedation, strong effect.Four reactions greatly: neural excitement and suppression, blood vessel
Shrink and expansion, the excitement of internal organs and suppression, metabolic enhancing and go down.When body negative and positive are in imbalance, stick
Acupuncture point can be allowed to tend to balance.
(2) Absorption of medicine.Medicine passes through skin surface topography horny layer and epidermis, enters extracellular matrix.Medicine
Thing molecule passes through skin microcirculation, enters blood circulation from extracellular fluid promptly disperse.Additionally, skin appendages sweat gland, hair follicle,
Sebaceous gland is also the passage of drug absorption.
Hypertension: refer to systemic arterial blood pressure (shrink pressure and/or diastolic pressure) increase as principal character (shrink pressure >=
140 millimetress of mercury, diastolic pressure >=90 millimetres of mercury), can be with the function of the organs such as the heart, brain, kidney or the clinic of organic lesion
Syndrome.Hypertension is modal chronic disease, is also the topmost risk factor of cardiovascular and cerebrovascular disease.The blood pressure of normal person is with interior
External environment change is fluctuated within the specific limits.Overall crowd, blood pressure level gradually rose with the age, the brightest to shrink pressure
Aobvious, but after 50 years old, diastolic pressure presents downward trend, and pulse pressure strengthens the most therewith.
Hypertension can be divided into two classes clinically: 1. essential hypertension: is a kind of to rise a height of main clinical manifestation with blood pressure
And the independent disease that the cause of disease is the clearest and the most definite, account for more than the 90% of all hyperpietics.2. secondary hypertension: be also called symptom
Property hypertension, in this kind of disease, the cause of disease is clear and definite, and hypertension is only one of clinical manifestation of this kind of disease, blood pressure can temporary or
Persistency raises.
The symptom of hypertension varies with each individual.Early stage is possible asymptomatic or symptom is inconspicuous, it can be common that dizziness, headache, neck
Item plate is tight, fatigue, cardiopalmus etc..Only blood pressure can be occurred after fatigue, psychentonia, anxious state of mind to raise, and extensive after rest
Multiple normal.Along with the course of disease extends, blood pressure the most persistently raises, and gradually there will be various symptom.Now it is referred to as delaying into type height
Blood pressure diseases.The common clinical symptoms of benign hypertension has headache, dizziness, absent minded, hypomnesis, limbs fiber crops
Wood, nocturia increase, cardiopalmus, uncomfortable in chest, weak etc..The symptom of hypertension has with blood pressure level and necessarily associates, and most symptoms are in anxiety
Or can increase the weight of after fatigue, after activity in early morning, blood pressure can raise rapidly, Hypertension in morning occurs, causes cardiocerebrovasculaevents events to mostly occur
In the morning.Even there will be the symptoms such as severe headache, vomiting, cardiopalmus, dizziness, seriously when blood pressure is suddenly increased to a certain degree
Time obnubilation, tic can occur, this just belongs to accelerated hypertension and hypertension critical illness, how can occur serious in a short time
The heart, brain, the infringement of the organ such as kidney and pathological changes, such as apoplexy, heart infarction, renal failure etc..The clinical manifestation of secondary hypertension is mainly
About the sings and symptoms of protopathy, hypertension is only one of its symptom.The blood pressure of secondary hypertension patient raises can be had
Himself feature, the hypertension as caused by coarctation of aorta can be only limitted to upper limb；The blood pressure that pheochromocytoma causes increases in battle array
The property sent out.The hypertension clinical stages standard of China's revision in 1979, by clinical manifestation, was divided into for three phases by hypertension.I phase blood
Pressure reaches Definite Hypertension level, and the diastolic pressure most of the time fluctuates between 12.0～13.3kPa (90～100mmHg), has a rest
After can recover normal；II phase blood pressure reaches Definite Hypertension level, and diastolic pressure, more than more than 13.3kPa (100mmHg), is had a rest
After can not be down to normal, and have the sign of left ventricular hypertrophy, skull bottom artery generally or local narrows, albuminuria slightly raises；Ⅲ
Phase blood pressure reaches Definite Hypertension level, diastolic pressure more than 14.7～16.0kPa (110～120mmHg), and have following symptom it
One: cerebrovas-cularaccident or hypertensive encephalopathy, left heart failure, renal failure, retinal hemorrhage or ooze out, with or without regarding nipple water
Swollen.
The traditional Chinese medical science does not has this noun of hypertension, but has the various clinical symptoms the most relevant with hypertension and corresponding treatment
The record of method existing more than 2000 years.The traditional Chinese medical science concentrates on the heart, liver, kidney to the cause of disease and the sick position of this disease, but based on Liver and kidney.Pathological changes
Procedure body is now " qi-blood disharmony, imbalance of YIN and YANG, phlegm and blood stasis ".The QI and blood theory of the traditional Chinese medical science thinks that " QI and blood " lives as human life
Dynamic important substance basis, " QI and blood " is to exist in dynamic motion mode, i.e. the merit of " gas row then blood leads to, the deficiency of vital energy then stasis "
Energy.Therefore, the exception of QI and blood running or obstacle, be the basic pathology change of some disease.Theory of Chinese medical science think " blood being the mother of qi,
Qi as the commander of blood ", " blood prosperous then gas foot, blood deficiency causing weakness of QI ".Under normal circumstances, gas and blood remain dynamic equilibrium, are referred to as " QI and blood punching
With ", if because of the impact of various internal and external factors, the dynamic equilibrium of QI and blood receives destruction, then corresponding pathological change occur, is referred to as
" qi-blood disharmony ".
The Pathogenesis Theory of imbalance of YIN and YANG, common application is in the middle of the understanding of hypertension.It is mainly reflected in Liver and kidney two dirty,
Other organ heart, spleen also have certain relation.Hyperactivity of YANG due to deficiency of YIN is the basic disease type of hypertension, but starts with the deficiency of YIN, particularly I,
II phase hypertension, its basic pathology starts from the deficiency of YIN.When the loss of essence cloudy in body arrives certain degree, yang-energy excited
Degree also can reduce with the exhaustion of cloudy essence, now, not only yin deficiency, and sun also void declines, and the disease of deficiency of both YIN and YANG occurs, this phase
Belonging to II, III phase pathological changes, this kind of is more common in course of disease length or aged patient more.Hyperactivity of YANG due to deficiency of YIN and deficiency of both YIN and YANG are common clinically, single
Pure yang hyperactivity or yang deficiency are less.Hyperactivity of YANG due to deficiency of YIN is more common in early metaphase, and deficiency of both YIN and YANG is more common in middle and advanced stage.Its evolution process is concluded
For: yang hyperactivity (or deficiency of YIN) → hyperactivity of YANG due to deficiency of YIN → deficiency of both YIN and YANG → yang deficiency.This is the TCM knowledge hypertension process by light → weight.
Developed to middle and late stage by above-mentioned pathological changes, produce many pathological products, most common with expectorant and the stasis of blood.From ancient Chinese medicine doctor until now,
Recognizing that the expectorant stasis of blood has important effect in the evolution of hypertension, when showing phlegm and blood stasis when, major part is sick
Journey for a long time, " pathogen usually intruding into collateral in protracted disease ", illustrate that lesion degree is heavier, obvious complication occurred, except dizzy, headache, the also thoracic obstruction, expectorant
Wet, edema etc., its sick position is mainly blood vessels stasis of blood plug, the most then relevant to spleen kidney.
Chinese traditional treatment hypertension, focuses on adjustment body equilibrium between yin and yang, occurs to fundamentally releasing hypertension
Immanent cause with development.It was verified that Chinese traditional treatment hypertension has blood pressure lowering improves the heart, brain, renal hemodynamic unevenness between supply and demand,
Thus it is obviously improved symptom, promote the recovery that cardiovascular and cerebrovascular vessel pathology changes.The traditional Chinese medical science thinks that Liver and kidney imbalance of YIN and YANG is that hypertension is produced
Raw inherent basis, so-called stagnation of phlegm, blood stasis are the most all the concrete reflections of the heart, brain, kidney pathological change.Blood stasis person, glycerol three
Ester is significantly raised, and blood capillary distortion incidence rate is higher than without blood stasis person, and in blood capillary, Hemodynamic environment is then slow compared with without blood stasis person.
Heart Doppler checks prompting myocardial strain or blood supply insufficiency, can be as the Diagnostic indicator of blood stasis.
The traditional Chinese medical science is thought, causing the original reason of hypertension is the imbalance of blood flow supply-demand relationship, You Yixin, the blood of brain kidney
Stream supply and demand do not weigh, because blood flow is in great demand by these three organ, therefore, the heart, brain, the blood flow supply and demand of kidney do not weigh, at blood
Generation that pressure raises and maintain and play a part particular importance, and the serious consequence that blood pressure raises, be also mainly manifested in the heart,
On brain, kidney.Therefore, to hypertension treatment, it should focus on the improvement of blood flow supply-demand relationship, adjusting from steady of active support body
Energy-conservation power.It seeks Treatment of Hypertension than singly, more has substantive significance.If emphasizing merely medicine Treatment of Hypertension, will go over to the opposite side, extensively
General application depressor, counter the jumping of boosting mechanism in evocator on the contrary, the effect of aggravation hypertension vicious cycle, aggravation blood flow supplies
Ask uneven, weaken self-adjustment further.
The hypertension point-application plaster of the present invention, may be used to lower section method and prepares: weigh Chinese medicine by recipe ingredient
Material.Chinese medicine in formula is ground into the Chinese medicine powder (Chinese medicine powder >=100 mesh) of more than 100 mesh, then according to mass percent is by 60
65% substrate and the mixing of 35 40% Chinese medicine powders, described substrate is the PUR of prior art, uses prior art heat of solution melten gel
Rear addition Chinese medicine powder mix homogeneously makes medicated core, then uses prior art to spread onto on medical proof fabric, obtains plaster, every piece of medicine
Rubberized fabric area is 6 × 6cm2, a diameter of 3.5cm of medicated core, medicated core quality is 1.3 2.0g.Described plaster can be adopted by pharmaceutical factory
Prepare by prior art production technology.
Further, in described plaster, use 61 63% substrate and the mixing of 37 39% Chinese medicine powders.
Optimal, in described plaster, use 62% substrate and the mixing of 38% Chinese medicine powder.
The hypertension point-application plaster of the present invention, for plaster shape, the property of medicine of plaster is the warmest, fragrant odour, in black.
Usage: external, is pasted on spring, Nei Guan, Shenmen, Taixi, Tai Chong, sp 6, tsu san li, Shenque acupuncture point, every day
Change dressings 1 time, within 4 months, be a course for the treatment of.
Medicine in the hypertension point-application plaster of the present invention passes through skin surface topography horny layer and epidermis, enters
Extracellular matrix.Drug molecule passes through skin microcirculation, enters blood circulation from extracellular fluid promptly disperse.Additionally, skin is attached
Belong to the passage that device sweat gland, hair follicle, sebaceous gland are also drug absorption.Hypertension is played important work by the stimulation at acupuncture point by plaster
With.External application stimulating acupoint, is equal to effect of acupuncture." Plain Questions, skin zone's opinion " is said: " beginning of all kinds of diseases and ailments is raw also, must be prior to fur.Evil
Visitor, in skin then opening of sweat pores, opens, and heresy enters objective in channels, and channels is the most then noted in passages through which vital energy circulates, and passages through which vital energy circulates the most then enters to give up in internal organs also ".The present invention
Hypertension point-application plaster for " qi-blood disharmony ", make, with Chinese medicine, the acupuncture point that plaster is pasted on, stimulation played at acupuncture point
Effect, reaches Yin Yang balancing, QI and blood punching and, make the effect of blood pressure drops.
Embodiment 1
Hypertension point-application plaster is made up of than the Chinese crude drug of component following quality: Radix Cynanchi Paniculati 0.1, Herba Leonuri 0.1,
Evodia rutaecarpa 0.1, Folium Artemisiae Argyi 0.1, Herba Schizonepetae 0.1, Radix orixae japonicae 0.025, Moschus 0.05.Chinese medicine powder accounts for 35% (0.525g), and substrate accounts for
65% (0.975g).
Embodiment 2
Hypertension point-application plaster is made up of than the Chinese crude drug of component following quality: Radix Cynanchi Paniculati 0.12, Herba Leonuri
0.12, Evodia rutaecarpa 0.12, Folium Artemisiae Argyi 0.12, Herba Schizonepetae 0.12, Radix orixae japonicae 0.08, Moschus 0.1.Chinese medicine powder accounts for 40% (0.68g), substrate
Account for 60% (1.02g).
Embodiment 3
Hypertension point-application plaster is made up of than the Chinese crude drug of component following quality: Radix Cynanchi Paniculati 0.15, Herba Leonuri
0.12, Evodia rutaecarpa 0.14, Folium Artemisiae Argyi 0.11, Herba Schizonepetae 0.11, Radix orixae japonicae 0.073, Moschus 0.06.Chinese medicine powder accounts for 37% (0.703g),
Substrate accounts for 63% (1.197g).
Embodiment 4
Hypertension point-application plaster is made up of than the Chinese crude drug of component following quality: Radix Cynanchi Paniculati 0.14, Herba Leonuri
0.15, Evodia rutaecarpa 0.13, Folium Artemisiae Argyi 0.10, Herba Schizonepetae 0.10, Radix orixae japonicae 0.082, Moschus 0.07.Chinese medicine powder accounts for 39% (0.702g),
Substrate accounts for 61% (1.098g).
Embodiment 5
Hypertension point-application plaster is made up of than the Chinese crude drug of component following quality: Radix Cynanchi Paniculati 0.15, Herba Leonuri
0.14, Evodia rutaecarpa 0.17, Folium Artemisiae Argyi 0.12, Herba Schizonepetae 0.12, Radix orixae japonicae 0.06, Moschus 0.09.Chinese medicine powder accounts for 38% (0.76g), base
Matter accounts for 62% (1.24g).
Embodiment 6
Hypertension point-application plaster is made up of than the Chinese crude drug of component following quality: Radix Cynanchi Paniculati 0.1, Herba Leonuri 0.1,
Evodia rutaecarpa 0.12, Folium Artemisiae Argyi 0.08, Herba Schizonepetae 0.08, Radix orixae japonicae 0.04, Moschus 0.1.Chinese medicine powder accounts for 40% (0.52g), and substrate accounts for
60% (0.78g).
Treatment example 1
Name: Lin, sex: female, the age: 76 years old, address: Fujian.Suffer from hypertension more than 20 year, take depressor for a long time
Norvasc, indapamide.Begin to use the hypertension point-application plaster time: in October, 2012, use front blood pressure 175/
110mmHg, uses hypertension 1 month blood pressure of point-application plaster of embodiment 1 to be down to 150/92mmHg, withdraws blood pressure lowering with regard to this
Medicine, is continuing with the full course for the treatment of, so far a blood pressure stabilization.
Treatment example 2
Name: Lu so-and-so, sex: female, the age: 50 years old, address: Fujian.Suffer from hypertension more than 10 year, take depressor for a long time
Metoprolol, Nifedipine controlled-release tablet.Begin to use the hypertension point-application plaster time: in October, 2012, use front blood
Pressure 166/99mmHg, uses hypertension 1 month blood pressure of point-application plaster of embodiment 1 to be down to 140/85mmHg, stops with regard to this
Taking depressor, be continuing with a full course for the treatment of, blood pressure is down to 125/80mmHg, and blood pressure is normal so far.
Treatment example 3
Name: Xiao, sex: man, age: 59 years old, address: Fujian.Suffer from hypertension more than 10 year, take depressor for a long time
Enalapril, valsartan.Begin to use the hypertension point-application plaster time: in November, 2012, use front blood pressure 165/
98mmHg, uses hypertension 1 month blood pressure of point-application plaster of embodiment 2 to be down to 136/89mmHg, withdraws depressor, continue
Continuing and use a full course for the treatment of, blood pressure is down to 128/85mmHg.Drug withdrawal blood pressure so far is normal.
Treatment example 4
Name: Chen, sex: man, age: 56 years old, address: Guangxi.Suffer from hypertension more than 10 year, take depressor for a long time
Captopril, nitrendipine.Begin to use the hypertension point-application plaster time: in May, 2012, use front blood pressure 168/
102mmHg, uses hypertension 1 month blood pressure of point-application plaster of embodiment 2 to be down to 135/95mmHg, withdraws depressor,
Being continuing with a full course for the treatment of, blood pressure is normal so far.
Treatment example 5
Name: Liao so-and-so, sex: man, the age: 55 years old, address: Guangxi.Suffer from more than 10 years of hypertension, take depressor for a long time
Losartan, amlodipine, triamterene.Begin to use the hypertension point-application plaster time: in June, 2012, use front blood
Pressure 165/105mmHg, uses hypertension 1 month blood pressure of point-application plaster of embodiment 3 to reduce to 138/94mmHg, withdraws fall
Pressing, is continuing with a full course for the treatment of, and after drug withdrawal, blood pressure is the most normal.
Treatment example 6
Name: Huang, sex: man, age: 48 years old, address: Guangxi.Suffer from hypertension more than 8 year, take depressor for a long time
Valsartan, nifedipine.Begin to use the hypertension point-application plaster time: in June, 2012, use front blood pressure 150/
99mmHg, uses 15 days blood pressures of hypertension point-application plaster of embodiment 4 to be down to 130/89mmHg, withdraws depressor, continue
Continuing and use a full course for the treatment of, after drug withdrawal, blood pressure is the most normal.
Treatment example 7
Name: Chen, sex: man, age: 61 years old, address: Shenzhen.Suffer from hypertension more than 10 year, take depressor for a long time
Metoprolol, nimodipine, indapamide.Begin to use the hypertension point-application plaster time: in January, 2013, use front blood
Pressure 165/108mmHg, uses hypertension 1 month blood pressure of point-application plaster of embodiment 4 to be down to 139/95mmHg, withdraws fall
Pressing, is continuing with a full course for the treatment of, and after drug withdrawal, blood pressure is always stable.
Treatment example 8
Name: Lin, sex: man, age: 71 years old, address: Shenzhen.Suffer from hypertension more than 10 year, take depressor for a long time
Compound hypoensive sheet, Zhenju Jiangya Tablet.Begin to use the hypertension point-application plaster time: in February, 2013, make
With front blood pressure 175/110mmHg, hypertension 1 month blood pressure of point-application plaster of embodiment 5 is used to be down to 163/96mmHg,
Withdrawing depressor, be continuing with a full course for the treatment of, after drug withdrawal, blood pressure is always stable.
Treatment example 9
Name: thank so-and-so, sex: man, age: 46 years old, address: Shenzhen.Suffer from hypertension more than 6 year, take depressor for a long time
Captopril, bisoprolol, indapamide.Begin to use the hypertension point-application plaster time: in June, 2013, before using
Blood pressure 175/115mmHg, uses 20 days blood pressures of hypertension point-application plaster of embodiment 5 to be down to 145/95mmHg, uses 1
Within individual month, blood pressure is down to 140/93mmHg, withdraws depressor, is continuing with a full course for the treatment of, and after drug withdrawal, blood pressure is the most normal.
Treatment example 10
Name: rely so-and-so, sex: man, the age: 80 years old, has coronary heart disease, address: Guangdong.Suffer from hypertension more than 20 year, long
Phase takes depressor amlodipine, losartan.Begin to use the hypertension point-application plaster time: in June, 2013, use front blood
Pressure 178/110mmHg, uses hypertension 1 month blood pressure of point-application plaster of embodiment 6 to reduce to 150/90-95mmHg, stops
Taking depressor, be continuing with a full course for the treatment of, drug withdrawal blood pressure so far is always stable.
Claims (9)
1. a hypertension point-application plaster, it is characterised in that: described hypertension point-application plaster, often patch plaster bag
Include the following quality Chinese crude drug than component:
Radix Cynanchi Paniculati 0.1 0.3, Herba Leonuri 0.1 0.4, Evodia rutaecarpa 0.1 0.3, Folium Artemisiae Argyi 0.1 0.3, Herba Schizonepetae 0.1 0.3, Radix orixae japonicae
0.05‐0.2。
Hypertension point-application plaster the most according to claim 1, it is characterised in that: described often patch plaster contains
0.05 0.1 mass are than the Moschus of component.
Hypertension point-application plaster according to claim 1, it is characterised in that:
Described often patch plaster includes the following quality Chinese crude drug than component:
3. Radix Cynanchi Paniculati 0.1 0.15, Herba Leonuri 0.1 0.15, Evodia rutaecarpa 0.1 0.17, Folium Artemisiae Argyi 0.08 0.12, Herba Schizonepetae 0.08
0.12, Radix orixae japonicae 0.025 0.082.
Hypertension point-application plaster the most according to claim 2, it is characterised in that: described often patch plaster contains
0.06 0.09 mass are than the Moschus of component.
Hypertension point-application plaster the most according to claim 3, it is characterised in that: described often patch plaster includes following
Quality is than the Chinese crude drug of component:
Radix Cynanchi Paniculati 0.12 0.14, Herba Leonuri 0.12 0.14, Evodia rutaecarpa 0.12 0.14, Folium Artemisiae Argyi 0.1 0.11, Herba Schizonepetae 0.1
0.11, Radix orixae japonicae 0.04 0.08.
Hypertension point-application plaster the most according to claim 3, it is characterised in that: described often patch plaster is by following matter
Measure and form than the Chinese crude drug of component:
Radix Cynanchi Paniculati 0.14, Herba Leonuri 0.15, Evodia rutaecarpa 0.13, Folium Artemisiae Argyi 0.1, Herba Schizonepetae 0.1, Radix orixae japonicae 0.082.
7. according to the hypertension point-application plaster described in claim 16 any one, it is characterised in that: described hypertension
The preparation method of sick point-application plaster is, described Chinese crude drug is ground into Chinese medicine powder, Chinese medicine powder >=100 mesh, then according to quality
60 65% substrate and 35 40% Chinese medicine powders are mixed by percentage ratio, and described substrate is PUR, add Chinese medicine after heat of solution melten gel
Powder mix homogeneously makes medicated core, then uses and spreads onto on medical proof fabric, obtains plaster, and every piece of plaster adhesive plaster area is 6 ×
6cm2, a diameter of 3.5cm of medicated core.
Hypertension point-application plaster the most according to claim 7, it is characterised in that: in described plaster, use 61
63% substrate and the mixing of 37 39% Chinese medicine powders.
Hypertension point-application plaster the most according to claim 8, it is characterised in that: in described plaster, use 62%
Substrate and the mixing of 38% Chinese medicine powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610881994.1A CN106309659A (en) | 2016-10-08 | 2016-10-08 | Acupoint plaster for hypertension |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610881994.1A CN106309659A (en) | 2016-10-08 | 2016-10-08 | Acupoint plaster for hypertension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106309659A true CN106309659A (en) | 2017-01-11 |
Family
ID=57821444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610881994.1A Pending CN106309659A (en) | 2016-10-08 | 2016-10-08 | Acupoint plaster for hypertension |
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| Country | Link |
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| CN (1) | CN106309659A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116098957A (en) * | 2023-01-06 | 2023-05-12 | 中国中医科学院广安门医院 | Acupoint application formula for reducing blood pressure |
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|---|---|---|---|---|
| CN1237430A (en) * | 1998-06-02 | 1999-12-08 | 王群盟 | Health-care medicine for curing hypertension and its preparation process |
| CN101167885A (en) * | 2007-10-11 | 2008-04-30 | 赵晓峰 | Traditional Chinese medicine sticking block for treating hypertension |
| CN104491100A (en) * | 2014-12-26 | 2015-04-08 | 青岛市市立医院 | Traditional Chinese medicine for treating hypertension and preparation method thereof |
-
2016
- 2016-10-08 CN CN201610881994.1A patent/CN106309659A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1237430A (en) * | 1998-06-02 | 1999-12-08 | 王群盟 | Health-care medicine for curing hypertension and its preparation process |
| CN101167885A (en) * | 2007-10-11 | 2008-04-30 | 赵晓峰 | Traditional Chinese medicine sticking block for treating hypertension |
| CN104491100A (en) * | 2014-12-26 | 2015-04-08 | 青岛市市立医院 | Traditional Chinese medicine for treating hypertension and preparation method thereof |
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| 白雪: "吴茱萸外敷涌泉穴治疗高血压", 《当代护士》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116098957A (en) * | 2023-01-06 | 2023-05-12 | 中国中医科学院广安门医院 | Acupoint application formula for reducing blood pressure |
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