CN104491100A - Traditional Chinese medicine for treating hypertension and preparation method thereof - Google Patents
Traditional Chinese medicine for treating hypertension and preparation method thereof Download PDFInfo
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- CN104491100A CN104491100A CN201410823962.7A CN201410823962A CN104491100A CN 104491100 A CN104491100 A CN 104491100A CN 201410823962 A CN201410823962 A CN 201410823962A CN 104491100 A CN104491100 A CN 104491100A
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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Abstract
The invention provides a traditional Chinese medicine for treating hypertension and a preparation method thereof and relates to the technical field of traditional Chinese medicines, which are used for solving the problem that existing medicines for treating hypertension are great in side effect, slow to take effect and inconvenient to take. The traditional Chinese medicine for treating hypertension is a patch which is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 20-50 parts of nux vomica, 80-100 parts of cinnamon, 80-100 parts of fructus evodiae, 80-100 parts of magnets, 20-40 parts of leonurus and 10-20 parts of radix bupleuri. The preparation method comprises the following steps: crushing; extracting; concentrating; and smearing on a non-woven fabric. The membrane of the traditional Chinese medicine patch provided by the invention is tore down, so that the patch is directly applied and is simple to use and convenient to carry. The patch is used for regulating qi and blood by stimulating acupuncture points, so that the peripheral vessel is expanded or the resistance of the peripheral vessel is reduced and the traditional Chinese medicine has the functions of inducing resuscitation, improving eyesight, activating blood and dredging collaterals and reducing blood pressure and relaxing spasm and is remarkable in treating various hypertension and heart diseases, stable in efficacy, quick to take effect, safe to medicate and free of side effects.
Description
Technical field
The present invention relates to the technical field of Chinese medicine, refer to that one treats hypertensive Chinese medicine and preparation method thereof especially.
Background technology
Hypertension is a kind of with the too high syndrome for main clinical manifestation of systemic arterial blood pressure, and namely diastolic pressure is more than 12 kPas (90 millimetres of mercury), or systolic pressure before 40 years old more than 18.7 kPas (140 millimetres of mercury); Essential hypertension and the large class of secondary hypertension two can be divided into.The former be a kind of cause of disease understand not yet completely increase common disease for main manifestations with arteriotony, belong to the disease category of " headache ", " dizzy ", " apoplexy " of the traditional Chinese medical science; The latter is because some disease causes, as one of the cardinal symptom of these diseases.
Along with the continuous progress of society, living standard and the material life quality of people constantly improve, and hypertension also becomes the common disease of social people now.Hypertension is multi-factor disease, and China's Prevalence of Hypertension rises year by year; At present, China hyperpietic reaches 200,000,000.Hypertension without systematic treating and control can cause the rake organ injuries such as the heart, brain, kidney, the health of the serious harm mankind.
At present, clinical treatment vascular hypertension is still based on Western medicine, drug effect is slow, hyperpietic needs ability stabilizing blood pressure of taking medicine all the life, but the symptom of patient can not be improved completely, and Western medicine action pathway is single, long-term extensive application will inevitably produce many side effect, may cause renal failure, can't neglect.In the last few years, occurred the Chinese herbal medicine of some treatment vascular hypertensions, it can be boiled into decoction, make medicated wine, make capsule etc. orally uses; Because Chinese herbal medicine decoction boils process complexity, difficult control of temperature, generally needs the same day and takes to boil the same day, and medical material waste is serious, meanwhile, if temperature controls improper when taking, takes and easily causes gastrointestinal upset afterwards, cause diarrhoea etc.; The oral liquid of the liquid such as medicated wine, is also inconvenient to cause it to take inconvenience because carrying; Capsule class Chinese herbal medicine, because of the use of gelatin in capsule manufacturing process etc., causes side effect to health, thus brings extra injury to patient body.
Summary of the invention
The present invention proposes one and treats hypertensive Chinese medicine and preparation method thereof, solve in prior art treat hypertensive drug side effect large, take effect slow and take inconvenient problem.
One of the present invention treats hypertensive Chinese medicine, its technical scheme is achieved in that described Chinese medicine is patch, is made up of the herbal raw material of following weight portion: Semen Strychni 20-50 part, Cortex Cinnamomi 80-100 part, Fructus Evodiae 80-100 part, Magnetitum 80-100 part, Herba Leonuri 20-40 part, Radix Bupleuri 10-20 part.
In herbal raw material of the present invention, Semen Strychni: nature and flavor are bitter, cold, poisonous; Return liver, spleen two warp; Main containing the multiple alkaloid such as strychnine and brucine; There is activating collaterals and eliminating stagnation, effect of reducing swelling and alleviating pain; Cure mainly numb limbs and tense tendons, paralysis, inappetence, mass in the abdomen, carbuncle pyogenic infections from tumour or sore, laryngopharynx swelling and pain.
Cortex Cinnamomi: acrid in the mouth, sweet, extremely hot in nature; Return kidney, spleen, the heart and Liver Channel; There is benefit fire supporing yang, guiding fire to origin, dispersing cold for relieving pain, effect of promoting the flow of QI-blood by warming the meridian; For sexual impotence cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, upward floating of YANG in deficiency condition, dizzy conjunctival congestion, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, and colic of cold type is suffered from abdominal pain, dysmenorrhea amenorrhea.
Fructus Evodiae: nature and flavor are pungent, peppery and bitter; Enter liver, stomach warp; There is effect of dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal; For headache due to JUE YIN disorder, colic of cold type stomachache, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, vomiting acid regurgitation, Diarrhoea.
Magnetitum: tool magnetic, has the smell of soil, tasteless; There is suppressing the hyperactive liver and subsiding YANG, hearing-improing and eyesight improving, tranquillizing the mind by relieving convulsion, effect of helping inspiration to relieve asthma; For having a dizzy spell, blurring of vision, Hiccough and deaf, palpitation with fear insomnia, asthma of suffering from a deficiency of the kidney.
Herba Leonuri: acrid in the mouth, hardship, property micro-enter; Enter the heart, liver, urinary bladder channel; Have invigorate blood circulation, blood stasis dispelling, regulating menstruation, the water that disappears effect; Cure mainly menoxenia, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria rush down blood, carbuncle skin infection; Take orally and can distend the blood vessels and make blood pressure drops, and have the adrenergic effect of antagonism, arteriosclerotic and neuropathic hypertension can be controlled.
Radix Bupleuri: acrid in the mouth, hardship, cold nature; Return liver, gallbladder, lung meridian; There is effect of reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang, preventing the attack (or recurrence) of malaria of bringing down a fever; Cure mainly cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis.
As the preferred technical scheme of one, be made up of the herbal raw material of following weight portion: Semen Strychni 50 parts, Cortex Cinnamomi 100 parts, Fructus Evodiae 100 parts, Magnetitum 100 parts, Herba Leonuri 35 parts, Radix Bupleuri 15 parts.
The present invention makes patch by Semen Strychni, Cortex Cinnamomi, Fructus Evodiae, Magnetitum, Herba Leonuri and Radix Bupleuri Chinese medicine formula through scientific and reasonable compatibility, directly stick on the Yongquan acupoint of human body, yang hyperactivity person sticks on TAICHONG acupoint, negative and positive deficiency person sticks on tsu san li, each subsides two acupuncture points place, alternately sticks, and uses simple, can not to health even skin damage, be convenient for carrying; By stimulating acupoint, acupuncture point based on Yongquan acupoint, by the activity of Yongquan acupoint by Drug Percutaneous Absorption, stimulation and active cell, improve the irritability of cell, regulate QI and blood, make peripheral blood vessel expand or reduce peripheral vascular resistance, conducting fire back to its origin, clear and coherent blood vessels, have have one's ideas straightened out, effect of eye-catching, latus rectum of invigorating blood circulation, blood pressure lowering spasmolytic, to treatment all kinds of hypertension, heart disease Be very effective, efficacy stability, instant effect, drug safety, has no side effect.
Science of arteries and veins is pointed out, arch of the foot is the position of kidney channel Yongquan acupoint, and the palm of the hand is the position of percardium through cave, palace, through conventional palm friction arch of the foot, can key kidney, regulate the flow of vital energy, Fructus Alpiniae Oxyphyllae, restoring normal coordination between the heart and kidney, make regulation between water and fire, coordination between the heart and kidney, can insomnia, dreaminess etc. be prevented and treated, also very effective in cure to hypertension.Foot and whole body relationship between Zang-Fu and channels-collaterals close, bear health total weight, therefore have person foot to be the mankind's " the second hearts ", it was observed that foot and overall relation object are similar to that fetus is flat to crouch in vola face, head is towards heel, buttocks is towards toes, namely internal organs are distributed in the middle part of sole, according to above principle and rule, stimulate sufficient cave, Whole Body function can be adjusted, treatment internal organs pathological changes.
A kind of preparation method for the treatment of hypertensive Chinese medicine of the present invention, its technical scheme is achieved in that and comprises the following steps: 1) get Semen Strychni, Cortex Cinnamomi, Fructus Evodiae, Herba Leonuri and Radix Bupleuri, roguing, and cleaning, dries, and pulverizes, obtains mixed powder; 2) in step 1) gained mixed powder, adding weight is mixed powder weight 3-5 water doubly, decocts 1-3 time, decocts 1-3h at every turn, filter, obtain filtrate and filtering residue respectively, for subsequent use; 3) in step 2) in gained filtering residue, adding mass concentration is the ethanol of 75-95%, reflux, extract, 1-3 time, filters, concentrated, obtains extractum, described ethanol consumption is 4-6 times of described mixed powder weight; 4) get Magnetitum, pulverize, sieve, obtain Magnetitum powder, add Magnetitum powder, step 3) gained extractum to step 2 respectively) in gained filtrate, mixing, stirs, obtains mixed liquor; 5) in step 4) gained mixed liquor, add glycerol, Carboxymethyl cellulose sodium, sorbitol successively, mix homogeneously, remove moisture, obtain thick paste, and be applied on non-woven fabrics, overlay film, section, obtains finished product.
The present invention by herbal raw material pulverize, extract, concentrate and be applied on non-woven fabrics, thus this patch obtained, herbal raw material kind is few, and raw material is common to be easy to get, low price, extracting method is simple, first tentatively extracts with water, then adopts ethanol to carry out second extraction, whole effective ingredient of Chinese herbal medicine are effectively reclaimed, and each raw material is carried out rational coordination, drug effect complements each other, and has given full play to the effect of each raw material; This preparation method is simple, and technological process is short, does not have special equipment requirements, with low cost, is easy to realize industrialization.
As the preferred technical scheme of one, in described step 5), gained thick paste smears the thickness of 1-2mm at 50-60 DEG C at non-woven fabrics, products obtained therefrom, and every note length is 5-10cm, and width is 3-5cm.Thick paste can spread upon on non-woven fabrics at 50-60 DEG C safety and precise, and the patch of this thickness can play drug effect for a long time; During use, also entirely sticked on Yongquan acupoint by the center aligned Yongquan acupoint of patch, this patch sticks firmly, difficult drop-off, sticks conveniently.
As the preferred technical scheme of one, in described step 5), the addition of glycerol, Carboxymethyl cellulose sodium and sorbitol is respectively 0.1-0.8%, 0.1-0.4%, 0.1-0.4% of mixed liquor weight.Under the effect of glycerol, Carboxymethyl cellulose sodium and sorbitol, Chinese herbal medicine thick paste is pasted onto on non-woven fabrics, thick paste firm pasting, and can play drug effect well; Reduce cost of manufacture, result of use is good.
As the preferred technical scheme of one, in described step 4), during Magnetitum grinding and sieving, the sieve number of employing is 120-200 order.Magnetitum powder is after 120-200 object sieved through sieve, and its granularity can mix with extracts of Chinese herbal medicine well, and thick paste is combined together uniformly, plays its effect fully, thus reach best drug effect in patch.
Usage and dosage: before sleep in evening, patch of the present invention is affixed on Yongquan acupoint place, and yang hyperactivity person sticks on TAICHONG acupoint, and negative and positive deficiency person sticks on tsu san li, each subsides two acupuncture points, alternately stick; Exchanging cards with personal and family details when becoming sworn brothers once every 24 hours, 7 days is a course for the treatment of.
Beneficial effect of the present invention: the present invention makes patch by Semen Strychni, Cortex Cinnamomi, Fructus Evodiae, Magnetitum, Herba Leonuri and Radix Bupleuri herbal raw material through scientific and reasonable compatibility, and the effect between each raw material is complemented each other, mutually promotes and mutually supplements; Gained patch directly sticks use, uses simple, sticks two acupuncture points place at every turn, alternately stick, can not to health even skin damage, be convenient for carrying, to treatment all kinds of hypertension, heart disease Be very effective, efficacy stability, instant effect, drug safety, has no side effect; Within 24 hours, change dressings once, dosage is little, and expense is low; Stimulating acupoint and Chinese medicine conditioning are combined, acupuncture point based on Yongquan acupoint, by the activity of Yongquan acupoint by Drug Percutaneous Absorption, stimulation and active cell, improves the irritability of cell, regulate QI and blood, peripheral blood vessel is made to expand or reduce peripheral vascular resistance, conducting fire back to its origin, clear and coherent blood vessels, have have one's ideas straightened out, effect of eye-catching, latus rectum of invigorating blood circulation, blood pressure lowering spasmolytic, dredging microcirculation, blood circulation promoting and blood stasis dispelling, is particularly suitable for the essential hypertension for the treatment of middle-aged and elderly people.
Accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, be briefly described to the accompanying drawing used required in embodiment or description of the prior art below, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
Fig. 1 is a kind of process chart preparing the method for the treatment of hypertensive Chinese medicine of the present invention.
Detailed description of the invention
Below in conjunction with the accompanying drawing in the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
One of the present invention treats hypertensive Chinese medicine, described Chinese medicine is patch, is made up of the herbal raw material of following weight portion: Semen Strychni 20-50 part, Cortex Cinnamomi 80-100 part, Fructus Evodiae 80-100 part, Magnetitum 80-100 part, Herba Leonuri 20-40 part, Radix Bupleuri 10-20 part.
Further, be made up of the herbal raw material of following weight portion: Semen Strychni 50 parts, Cortex Cinnamomi 100 parts, Fructus Evodiae 100 parts, Magnetitum 100 parts, Herba Leonuri 35 parts, Radix Bupleuri 15 parts.
Accompanying drawings 1, a kind of preparation method for the treatment of hypertensive Chinese medicine of the present invention, comprises the following steps: 1) get Semen Strychni, Cortex Cinnamomi, Fructus Evodiae, Herba Leonuri and Radix Bupleuri, roguing, and cleaning, dries, and pulverizes, obtains mixed powder; 2) in step 1) gained mixed powder, adding weight is mixed powder weight 3-5 water doubly, decocts 1-3 time, decocts 1-3h at every turn, filter, obtain filtrate and filtering residue respectively, for subsequent use; 3) in step 2) in gained filtering residue, adding mass concentration is the ethanol of 75-95%, reflux, extract, 1-3 time, filters, concentrated, obtains extractum, described ethanol consumption is 4-6 times of described mixed powder weight; 4) get Magnetitum, pulverize, sieve, obtain Magnetitum powder, add Magnetitum powder, step 3) gained extractum to step 2 respectively) in gained filtrate, mixing, stirs, obtains mixed liquor; 5) in step 4) gained mixed liquor, add glycerol, Carboxymethyl cellulose sodium, sorbitol successively, mix homogeneously, remove moisture, obtain thick paste, and be applied on non-woven fabrics, overlay film, section, obtains finished product.
Further, in described step 5), gained thick paste smears the thickness of 1-2mm at 50-60 DEG C at non-woven fabrics, products obtained therefrom, and every note length is 5-10cm, and width is 3-5cm.
Further, in described step 5), the addition of glycerol, Carboxymethyl cellulose sodium and sorbitol is respectively 0.1-0.8%, 0.1-0.4%, 0.1-0.4% of mixed liquor weight.
Again further, in described step 4), during Magnetitum grinding and sieving, the sieve number of employing is 120-200 order.
embodiment one
Get Semen Strychni 20g, Cortex Cinnamomi 90g, Fructus Evodiae 90g, Herba Leonuri 40g and Radix Bupleuri 10g, roguing, cleaning, dries, and pulverizes, obtains mixed powder; In above-mentioned mixed powder, add the water that weight is mixed powder weight 5 times, decoct 2 times, each 1h, filter, obtain filtrate and filtering residue respectively, for subsequent use; In above-mentioned filtering residue, adding mass concentration is the ethanol of 95%, reflux, extract, 1 time, filters, and concentrated, obtain extractum, ethanol consumption is 6 times of mixed powder weight; Get Magnetitum 90g, pulverize, adopt 200 object screen clothes to sieve, obtain Magnetitum powder, Magnetitum powder, above-mentioned extractum are added in above-mentioned filtrate respectively, mixing, stir, obtain mixed liquor; In above-mentioned mixed liquor, add glycerol, Carboxymethyl cellulose sodium, sorbitol successively, mix homogeneously, remove moisture, obtain thick paste, and be applied on non-woven fabrics, overlay film, section, obtains finished product.
This patch is prepared from by the Semen Strychni of 20 weight portions, the Cortex Cinnamomi of 90 weight portions, the Fructus Evodiae of 90 weight portions, the Magnetitum of 90 weight portions, the Herba Leonuri of 40 weight portions, the Radix Bupleuri of 10 weight portions, directly sticks use; Before sleep in evening, stick in Yongquan acupoint place, exchange cards with personal and family details when becoming sworn brothers once before second night sleep, medication is convenient, and curative effect is lasting again; Yang hyperactivity person sticks on TAICHONG acupoint, and negative and positive deficiency person sticks on tsu san li, and each subsides two acupuncture points, alternately stick; This patch is Chinese herbs paste, sticks use outward, to treatment all kinds of hypertension, heart disease Be very effective, and efficacy stability, instant effect, drug safety, has no side effect, and also can not damage body surface's skin, sticks firmly, difficult drop-off; Conducting fire back to its origin, dredging microcirculation, blood circulation promoting and blood stasis dispelling, is particularly suitable for the essential hypertension for the treatment of middle-aged and elderly people.
embodiment two
Get Semen Strychni 50g, Cortex Cinnamomi 100g, Fructus Evodiae 100g, Herba Leonuri 35g and Radix Bupleuri 15g, roguing, cleaning, dries, and pulverizes, obtains mixed powder; In above-mentioned mixed powder, add the water that weight is mixed powder weight 3 times, decoct 3 times, each 2h, filter, obtain filtrate and filtering residue respectively, for subsequent use; In above-mentioned filtering residue, adding mass concentration is the ethanol of 75%, reflux, extract, 3 times, filters, and concentrated, obtain extractum, ethanol consumption is 4 times of mixed powder weight; Get Magnetitum 100g, pulverize, adopt 120 object screen clothes to sieve, obtain Magnetitum powder, Magnetitum powder, above-mentioned extractum are added in above-mentioned filtrate respectively, mixing, stir, obtain mixed liquor; In above-mentioned mixed liquor, adding weight is successively the glycerol of mixed liquor weight 0.1%, Carboxymethyl cellulose sodium, 0.4% sorbitol of 0.4%, mix homogeneously, remove moisture, obtain thick paste, and it is smeared on non-woven fabrics the thickness of 2mm at 50 DEG C, overlay film, section, obtains finished product.
The specification of this patch is length be 10cm width is 5cm, be prepared from by the Semen Strychni of 50 weight portions, the Cortex Cinnamomi of 100 weight portions, the Fructus Evodiae of 100 weight portions, the Magnetitum of 100 weight portions, the Herba Leonuri of 35 weight portions, the Radix Bupleuri of 15 weight portions, directly stick use; Before sleep in evening, directly stick in Yongquan acupoint place, exchange cards with personal and family details when becoming sworn brothers once before second night sleep, medication is convenient, and curative effect is lasting again; Yang hyperactivity person sticks on TAICHONG acupoint, and negative and positive deficiency person sticks on tsu san li, and each subsides two acupuncture points, alternately stick; This patch is Chinese herbs paste, sticks use outward, to treatment all kinds of hypertension, heart disease Be very effective, and efficacy stability, instant effect, drug safety, has no side effect, and also can not damage body surface's skin, sticks firmly, difficult drop-off; Conducting fire back to its origin, dredging microcirculation, blood circulation promoting and blood stasis dispelling, is particularly suitable for the essential hypertension for the treatment of middle-aged and elderly people.
embodiment three
Get Semen Strychni 40g, Cortex Cinnamomi 80g, Fructus Evodiae 80g, Herba Leonuri 20g and Radix Bupleuri 20g, roguing, cleaning, dries, and pulverizes, obtains mixed powder; In above-mentioned mixed powder, add the water that weight is mixed powder weight 4 times, decoct 1 time, each 3h, filter, obtain filtrate and filtering residue respectively, for subsequent use; In above-mentioned filtering residue, adding mass concentration is the ethanol of 85%, reflux, extract, 2 times, filters, and concentrated, obtain extractum, ethanol consumption is 5 times of mixed powder weight; Get Magnetitum 80g, pulverize, adopt 180 object screen clothes to sieve, obtain Magnetitum powder, Magnetitum powder, above-mentioned extractum are added in above-mentioned filtrate respectively, mixing, stir, obtain mixed liquor; In above-mentioned mixed liquor, add glycerol, the Carboxymethyl cellulose sodium of 0.2%, the sorbitol of 0.2% that weight is mixed liquor weight 0.5% successively, mix homogeneously, remove moisture and obtain thick paste, and at 60 DEG C, it is smeared on non-woven fabrics the thickness of 1mm, overlay film, section, obtains finished product.
The specification of this patch is length be 5cm width is 3cm, is prepared from, directly sticks use by the Semen Strychni of 40 weight portions, the Cortex Cinnamomi of 80 weight portions, the Fructus Evodiae of 80 weight portions, the Magnetitum of 80 weight portions, the Herba Leonuri of 20 weight portions, the Radix Bupleuri of 20 weight portions; Before sleep in evening, directly stick in Yongquan acupoint place, exchange cards with personal and family details when becoming sworn brothers once before second night sleep, medication is convenient, and curative effect is lasting again; Yang hyperactivity person sticks on TAICHONG acupoint, and negative and positive deficiency person sticks on tsu san li, and each subsides two acupuncture points, alternately stick; This patch is Chinese herbs paste, sticks use outward, to treatment all kinds of hypertension, heart disease Be very effective, and efficacy stability, instant effect, drug safety, has no side effect, and also can not damage body surface's skin, sticks firmly, difficult drop-off; Conducting fire back to its origin, dredging microcirculation, blood circulation promoting and blood stasis dispelling, is particularly suitable for the essential hypertension for the treatment of middle-aged and elderly people.
embodiment four
Get Semen Strychni 20g, Cortex Cinnamomi 100g, Fructus Evodiae 100g, Herba Leonuri 20g and Radix Bupleuri 10g, roguing, cleaning, dries, and pulverizes, obtains mixed powder; In above-mentioned mixed powder, add the water that weight is mixed powder weight 4 times, decoct 3 times, each 3h, filter, obtain filtrate and filtering residue respectively, for subsequent use; In above-mentioned filtering residue, adding mass concentration is the ethanol of 95%, reflux, extract, 3 times, filters, and concentrated, obtain extractum, ethanol consumption is 5 times of mixed powder weight; Get Magnetitum 100g, pulverize, adopt 150 object screen clothes to sieve, obtain Magnetitum powder, Magnetitum powder, above-mentioned extractum are added in above-mentioned filtrate respectively, mixing, stir, obtain mixed liquor; In above-mentioned mixed liquor, add glycerol, the Carboxymethyl cellulose sodium of 0.1%, the sorbitol of 0.1% that weight is mixed liquor weight 0.8% successively, mix homogeneously, remove moisture, obtain thick paste, and it is smeared on non-woven fabrics the thickness of 1.5mm at 55 DEG C, overlay film, section, obtains finished product.
The specification of this patch is length be 8cm width is 4cm, be prepared from by the Semen Strychni of 20 weight portions, the Cortex Cinnamomi of 100 weight portions, the Fructus Evodiae of 100 weight portions, the Magnetitum of 100 weight portions, the Herba Leonuri of 20 weight portions, the Radix Bupleuri of 10 weight portions, directly stick use; Before sleep in evening, directly stick in Yongquan acupoint place, exchange cards with personal and family details when becoming sworn brothers once before second night sleep, medication is convenient, and curative effect is lasting again; Yang hyperactivity person sticks on TAICHONG acupoint, and negative and positive deficiency person sticks on tsu san li, and each subsides two acupuncture points, alternately stick; This patch is Chinese herbs paste, sticks use outward, to treatment all kinds of hypertension, heart disease Be very effective, and efficacy stability, instant effect, drug safety, has no side effect, and also can not damage body surface's skin, sticks firmly, difficult drop-off; Conducting fire back to its origin, dredging microcirculation, blood circulation promoting and blood stasis dispelling, is particularly suitable for the essential hypertension for the treatment of middle-aged and elderly people.
embodiment five
Get Semen Strychni 30g, Cortex Cinnamomi 100g, Fructus Evodiae 100g, Herba Leonuri 30g and Radix Bupleuri 10g, roguing, cleaning, dries, and pulverizes, obtains mixed powder; In above-mentioned mixed powder, add the water that weight is mixed powder weight 5 times, decoct 3 times, each 3h, filter, obtain filtrate and filtering residue respectively, for subsequent use; In above-mentioned filtering residue, adding mass concentration is the ethanol of 75%, reflux, extract, 3 times, filters, and concentrated, obtain extractum, ethanol consumption is 5 times of mixed powder weight; Get Magnetitum 100g, pulverize, sieve, obtain Magnetitum powder, Magnetitum powder, above-mentioned extractum are added in above-mentioned filtrate respectively, mixing, stir, obtain mixed liquor; In above-mentioned mixed liquor, add glycerol, Carboxymethyl cellulose sodium, sorbitol successively, mix homogeneously, remove moisture and obtain thick paste, and be applied on non-woven fabrics, overlay film, section, obtains finished product.
This patch is prepared from by the Semen Strychni of 30 weight portions, the Cortex Cinnamomi of 100 weight portions, the Fructus Evodiae of 100 weight portions, the Magnetitum of 100 weight portions, the Herba Leonuri of 30 weight portions, the Radix Bupleuri of 10 weight portions, directly stick use, before sleep in evening, directly stick in Yongquan acupoint place, exchange cards with personal and family details when becoming sworn brothers again once before second night sleep, medication is convenient, and curative effect is lasting; Yang hyperactivity person sticks on TAICHONG acupoint, and negative and positive deficiency person sticks on tsu san li, and each subsides two acupuncture points, alternately stick; This patch is Chinese herbs paste, sticks use outward, to treatment all kinds of hypertension, heart disease Be very effective, and efficacy stability, instant effect, drug safety, has no side effect, and also can not damage body surface's skin, sticks firmly, difficult drop-off; Conducting fire back to its origin, dredging microcirculation, blood circulation promoting and blood stasis dispelling, is particularly suitable for the essential hypertension for the treatment of middle-aged and elderly people.
The present invention is set forth further below in conjunction with concrete clinical case:
Case 1: Zhang, female, 50 years old, often headache at ordinary times, dizziness, feeling of fullness in the head, Nausea and vomiting, tinnitus, dim eyesight, forgetful, absent minded, irritability, nervousness, insomnia, unhappiness, weak, numb limbs and tense tendons, Wry Neck uncomfortable, cardiopalmus; During health check-up, the systolic pressure of blood pressure is 160mmHg(i.e. 160 millimetress of mercury), diastolic pressure is 100mmHg(i.e. 100 millimetress of mercury); In former years, time uncomfortable, have Western medicine blood pressure lowering, carries Western medicine throughout the year.From in April, 2013, cut out other medicines, stick Chinese herbs paste of the present invention, when sticking 1 course for the treatment of, blood pressure slowly declines, and health recovers gradually, and the mental status takes a turn for the better, and sleep quality improves; After sticking 3 courses for the treatment of, blood pressure recovers normal, and headache, dizzy phenomenon disappear, and cardiopalmus and unhappy symptom also disappear, and extremity are no longer numb, and the mental status is fine, happy; Continue observation 6 months, check a blood pressure fortnight, blood pressure maintains normal level (110mmHg/75mmHg) always, is damaged and the left heart that expands also recovers normal by hypertension meanwhile.Further, it is during sticking Chinese herbs paste of the present invention, does not occur erythema, edema and phenomenon of itching by the skin pasting acupuncture point place.
Contrast case, the Zhang in case 1, during in January, 2013 in March, 2013, namely before not sticking Chinese herbs paste of the present invention, once went to have seen traditional Chinese medical science clinic, sticked certain Traditional Chinese medicine hypotensive paste, 1 navel paster, and 2 soles paste, and pasted and had a rest 1 day for 3 days; During sticking this medicine, blood pressure drops is less, and symptom alleviates not obvious, sometimes also needs to take Western medicine secondary buck; And once paste 3 and paste, dosage is large, and stick period, this patch easily comes off, and have edema phenomenon by the skin pasting acupuncture point place, the Chinese medical concrete on patch is easily pasted on skin, and not easy cleaning, skin of making dirty, causes secondary injury to skin.
Case 2: Lee, man, 35 years old, because operating pressure is large, be busy with one's work, daily dinner party was many, lacks motion; Be typical three-hypers through hospital diagnosis tentative diagnosis, hypertension, hyperlipidemia and hyperglycemia, the systolic pressure of blood pressure is 180mmHg, and diastolic pressure is 105mmHg.Stick further consultation after 1 course for the treatment of of patch of the present invention, blood pressure slowly declines, and chores is concentrated, and diet recovers normal, and sleep quality is good; After sticking 3 courses for the treatment of, blood pressure recovers normal, and now, systolic pressure is 120mmHg, and diastolic pressure is 75mmHg, and the mental status is fine, and health is light, is in a cheerful frame of mind; Advise its less salt low fat diet, note easy combination, keep happy; Continue observation 1 year, check a blood pressure fortnight, blood pressure maintains normal level (120mmHg/75mmHg) always, has no bounce-back.Further, it is during sticking Chinese herbs paste of the present invention, by skin smooth, the exquisiteness of pasting acupuncture point place, does not occur erythema, edema, itches and other allergic phenomena.
Case 3: field, man, 57 years old, checked out to suffer from hypertension before 10 years, systolic pressure is at that time 190mmHg, and diastolic pressure is 110mmHg, takes Qi chrysanthemum hypertension pill therebetween, but unstable blood pressure is fixed, time height time low, sometimes also have the symptom of headache, dizzy and ophthalmic bloated pain; Also took the hypertensive Chinese medicine decoction for the treatment of, after these medicines of long-term taking, caused stomach discomfort, always nausea and vomiting, anorexia; From in JIUYUE, 2012, cut out all medicines, stick patch of the present invention, after sticking 1 course for the treatment of, blood pressure reduces, and dizzy, headache phenomenon disappears, and appetite is recovered gradually; After sticking 3 courses for the treatment of, blood pressure recovers normal, and now, systolic pressure is 110mmHg, and diastolic pressure is 80mmHg, and the mental status is fine, and health is light, is in a cheerful frame of mind, and gastropathy is fully recovered; Continue to observe half a year, check a blood pressure fortnight, blood pressure maintains normal level always, has no bounce-back.Further, it is during sticking Chinese herbs paste of the present invention, does not occur erythema, edema and phenomenon of itching by the skin pasting acupuncture point place.
Case 4: Bai, man, 72 years old, frequent dizziness, headache, dim eyesight, sleep is not good enough, suffers from coronary heart disease, hypertension, rheumatoid disease, and the systolic pressure of blood pressure is 170mmHg, diastolic pressure is 110mmHg, and the state of an illness continues 10 years, dimly red tongue, thick and greasy fur, inappetence, takes the Western medicine such as captopril, nimodipine tablet therebetween, but unstable blood pressure is fixed, time height time low, once discontinue medication, blood pressure raises at once; From in January, 2013, cut out other medicines, stick patch of the present invention, after sticking 1 course for the treatment of, blood pressure reduces, and dizzy, headache phenomenon disappears, and vision is clear; After sticking 3 courses for the treatment of, blood pressure recovers normal, and now, systolic pressure is 120mmHg, and diastolic pressure is 80mmHg, and the mental status is fine, and health is light, and sleep quality is high, and diet recovers normal; Continue observation 1 year, check a blood pressure fortnight, blood pressure maintains normal level always, has no bounce-back.Further, it is during sticking Chinese herbs paste of the present invention, fine and smooth, smooth by the skin pasting acupuncture point place, does not occur erythema, edema, itches and allergic phenomena.
Contrast case, Bai in case 4, during in March, 2012 in May, 2012, namely before not sticking Chinese herbs paste of the present invention, once went to have seen traditional Chinese medical science clinic, sticked certain Traditional Chinese medicine hypotensive paste, this patch was sticked 8-10 hour on the Yongquan acupoint at the both feet end, morning next day extracts, every night once; During sticking this medicine, blood pressure declines to some extent, and when every dusk, blood pressure starts again to raise, and also needs if desired to take Western medicine secondary buck; Have the phenomenon of itching by the skin pasting acupuncture point place, patch easily comes off, and sticks insecure.
Case 5: Deng, female, 63 years old, in July, 2008 seeks medical advice because falling in a swoon, and recording its systolic pressure is 200mmHg, and diastolic pressure is 105mmHg, be diagnosed as hypertension, through giving blood pressure lowering, expander in hospital, suiting the medicine to the illness and Supporting Therapy, and frequent Aspirin enteric coatel tablets, carry this tablet throughout the year, its systolic pressure maintains 170mmHg, diastolic pressure maintains 90mmHg, once cut out Aspirin Enteric-coated Tablets, blood pressure rises very fast.From in June, 2013, cut out depressor, stick patch of the present invention, after sticking 1 course for the treatment of, blood pressure reduces, and happy, appetite increases; After sticking 3 courses for the treatment of, blood pressure recovers normal, and now, systolic pressure is 110mmHg, and diastolic pressure is 70mmHg, and the mental status is fine, and health is light, and sleep quality is high; Continue observation 1 year, check a blood pressure fortnight, blood pressure maintains normal level always, has no bounce-back.Further, it is during sticking Chinese herbs paste of the present invention, and by skin smooth, the exquisiteness of pasting acupuncture point place, cortex is normal, does not occur erythema, edema and phenomenon of itching.
Contrast case, Deng in case 5, during in January, 2013 in March, 2013, namely before not sticking Chinese herbs paste of the present invention, once went to have seen traditional Chinese medical science clinic, sticked certain Traditional Chinese medicine hypotensive paste, this patch was sticked sp 6 in human body lower limbs with lower limb, the foot outer surface down to Yongquan acupoint, Xiangu point line, stick 8-18 hour, the next day, carries out sticking next time; During sticking this medicine, blood pressure declines to some extent, and unstable blood pressure is fixed, after stopping sticks, easily recurs; Have the phenomenon of erythema by the skin pasting acupuncture point place, patch easily comes off, and sticks insecure.
Chinese herbs paste of the present invention is prepared from through scientific and reasonable compatibility by Semen Strychni, Cortex Cinnamomi, Fructus Evodiae, Magnetitum, Herba Leonuri and Radix Bupleuri herbal raw material, and the effect between each raw material is complemented each other, and mutually promotes and mutually supplements; Gained patch directly sticks use, uses simple, sticks two acupuncture points place at every turn, alternately stick, can not to health even skin damage, be convenient for carrying, to treatment all kinds of hypertension, heart disease Be very effective, efficacy stability, instant effect, drug safety, has no side effect; Within 24 hours, change dressings once, dosage is little, and expense is low; Stimulating acupoint and Chinese medicine conditioning are combined, acupuncture point based on Yongquan acupoint, by the activity of Yongquan acupoint by Drug Percutaneous Absorption, stimulation and active cell, improves the irritability of cell, regulate QI and blood, peripheral blood vessel is made to expand or reduce peripheral vascular resistance, conducting fire back to its origin, clear and coherent blood vessels, have have one's ideas straightened out, effect of eye-catching, latus rectum of invigorating blood circulation, blood pressure lowering spasmolytic, dredging microcirculation, blood circulation promoting and blood stasis dispelling, is particularly suitable for the essential hypertension for the treatment of middle-aged and elderly people.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. treat a hypertensive Chinese medicine, it is characterized in that, described Chinese medicine is patch, is made up of the herbal raw material of following weight portion:
Semen Strychni 20-50 part, Cortex Cinnamomi 80-100 part, Fructus Evodiae 80-100 part, Magnetitum 80-100 part, Herba Leonuri 20-40 part, Radix Bupleuri 10-20 part.
2. the hypertensive Chinese medicine for the treatment of according to claim 1, is characterized in that, is made up of the herbal raw material of following weight portion:
Semen Strychni 50 parts, Cortex Cinnamomi 100 parts, Fructus Evodiae 100 parts, Magnetitum 100 parts, Herba Leonuri 35 parts, Radix Bupleuri 15 parts.
3. the preparation method of the hypertensive Chinese medicine for the treatment of according to any one of claim 1 or 2, is characterized in that, comprise the following steps:
1) get Semen Strychni, Cortex Cinnamomi, Fructus Evodiae, Herba Leonuri and Radix Bupleuri, roguing, cleaning, dries, and pulverizes, obtains mixed powder;
2) in step 1) gained mixed powder, adding weight is mixed powder weight 3-5 water doubly, decocts 1-3 time, decocts 1-3h at every turn, filter, obtain filtrate and filtering residue respectively, for subsequent use;
3) in step 2) in gained filtering residue, adding mass concentration is the ethanol of 75-95%, reflux, extract, 1-3 time, filters, concentrated, obtains extractum, described ethanol consumption is 4-6 times of described mixed powder weight;
4) get Magnetitum, pulverize, sieve, obtain Magnetitum powder, add Magnetitum powder, step 3) gained extractum to step 2 respectively) in gained filtrate, mixing, stirs, obtains mixed liquor;
5) in step 4) gained mixed liquor, add glycerol, Carboxymethyl cellulose sodium, sorbitol successively, mix homogeneously, remove moisture, obtain thick paste, and be applied on non-woven fabrics, overlay film, section, obtains finished product.
4. the preparation method of the hypertensive Chinese medicine for the treatment of according to claim 3, is characterized in that:
In described step 5), gained thick paste smears the thickness of 1-2mm at 50-60 DEG C at non-woven fabrics, products obtained therefrom, and every note length is 5-10cm, and width is 3-5cm.
5. the preparation method of the hypertensive Chinese medicine for the treatment of according to claim 4, is characterized in that:
In described step 5), the addition of glycerol, Carboxymethyl cellulose sodium and sorbitol is respectively 0.1-0.8%, 0.1-0.4%, 0.1-0.4% of mixed liquor weight.
6. the preparation method of the hypertensive Chinese medicine for the treatment of according to claim 5, is characterized in that:
In described step 4), during Magnetitum grinding and sieving, the sieve number of employing is 120-200 order.
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| CN106309659A (en) * | 2016-10-08 | 2017-01-11 | 庄之衍 | Acupoint plaster for hypertension |
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|---|---|---|---|---|
| JPH0948734A (en) * | 1995-08-03 | 1997-02-18 | Sadao Nakayama | Pharmacodynamically effective composition comprising chinese medicine and natural product |
| CN104517179A (en) * | 2014-11-04 | 2015-04-15 | 无锡雅座在线科技发展有限公司 | Intelligent catering daily analysis system based on cloud storage and cloud computation |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0948734A (en) * | 1995-08-03 | 1997-02-18 | Sadao Nakayama | Pharmacodynamically effective composition comprising chinese medicine and natural product |
| CN104517179A (en) * | 2014-11-04 | 2015-04-15 | 无锡雅座在线科技发展有限公司 | Intelligent catering daily analysis system based on cloud storage and cloud computation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106309659A (en) * | 2016-10-08 | 2017-01-11 | 庄之衍 | Acupoint plaster for hypertension |
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Application publication date: 20150408 |