CN103908526A

CN103908526A - Pharmaceutical composition used for preventing or/and treating hypertension, and applications thereof

Info

Publication number: CN103908526A
Application number: CN201410083508.2A
Authority: CN
Inventors: 朱喜莲
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-03-07
Filing date: 2014-03-07
Publication date: 2014-07-09

Abstract

The invention provides a pharmaceutical composition used for preventing or/and treating hypertension, and applications thereof. The pharmaceutical composition comprises, by weight, 800 to 1200 parts of chrysanthemum, 0 to 600 parts of eucommia, 300 to 600 parts of prunella vulgaris, 300 to 600 parts of ligusticum wallichii, 0 to 600 parts of folium mori, 100 to 300 parts of radix angelicae, 100 to 300 parts of cortex moutan, 0 to 200 parts of fructus viticis, and 50 to 120 parts of asarum herb. The pharmaceutical composition can be used for preventing or/and treating hypertension effectively.

Description

For preventing or/and treat hypertensive pharmaceutical composition and application thereof

Technical field

The invention belongs to the field of Chinese medicines, particularly, relate to for prevention or/and treat hypertensive pharmaceutical composition and application thereof, more specifically, relate to for prevention or/and treat hypertensive pharmaceutical composition, for prevention or/and treat hypertensive medicine and preparation method thereof.

Background technology

Hypertension is divided into constitutional and Secondary cases.Constitutional is a kind of disease of chronic cardiovascular of general, Secondary cases be by other diseases as kidney, endocrine, caused a kind of disease such as intracranial lesion, belong to " headache, dizzy " scope, by factors such as seven emotions, deficient, drinking and eating irregularly, make yin-Yang disequilibrium, and cause conscience yang hyperactivity or the hepatic and renal YIN deficiency, generally by consolidation void, be yang hyperactivity as before, continue as hyperactivity of YANG due to deficiency of YIN, eventually to deficiency of both YIN and YANG.

At present, reduce and prevent and treat hypertension raise Chinese and western drugs a lot, although it can make hypertension be eased very soon, take these Chinese medicine and western medicine and also there will be a series of side effect and inconvenience.Thereby, be used for the treatment of hypertensive medicine still to be improved.

Summary of the invention

The present invention one of is intended to solve the problems of the technologies described above at least to a certain extent or at least provides a kind of useful business to select.For this reason, one object of the present invention is to propose one and can be effective to prevention or/and treat hypertensive pharmaceutical composition.

The following discovery of the present invention based on inventor completes: prazosin is the stressed blocker of the one in sympathetic inhibitor, selective exclusion vascular smooth muscle postsynaptic membrane, tremulous pulse and vein that antagonism norepinephrine causes shrink, therefore expansible tremulous pulse, reduce Peripheral resistance, before and after alleviating heart, load, improve left heart function, thereby reduce blood pressure; Reserpine is SNE depressant, mainly that after hindering joint, adrenergic teleneuron is stored position (vesicle) in conjunction with norepinephrine and precursor substance dopamine thereof, reduce that mediator that mediator is released into its maincenter adrenergic of postsynaptic membrane adrenoceptor and serotoninergic neuron is discharged gradually and reserves reduce, therefore can decreased heart rate, blood vessel dilating, reduce blood pressure, and have calm and stable effect.But, take there will be that nasal obstruction headache, dizziness, gastrointestinal secretion increase after these Western medicine, diarrhoea, drowsiness, weak etc., long-term taking can cause serious dysthymia, Peptic Ulcers and arrhythmia and myocardial function are suppressed etc.In addition, liver-heat type hypertension, answers calming liver and clearing heat, available Decoction of Gentiana for Purging the Liver-fire; Type of deficiency of YIN leading to hyper activity of YANG hypertension, answers nourishing YIN for attracting YANG, available TIANMA GOUTENG YIN; Hypertension of deficiency of yin of liver and kidney type is answered nourishing the kidney and liver, available Radix Polygoni Multiflori soup; Deficiency of both YIN and YANG type hypertension, answers nourishing YIN and invigorating YANG, available dihuang drink.Above example can be added and subtracted according to state of an illness symptom, treating both the principal and secondary aspects of a disease, and hypertension will soon be eased.But also there will be a series of side effect and inconvenience simultaneously, for example: along with socio-economic development and growth in the living standard, people's working time is more and more nervous, thereby in the process that decocts Chinese medicine, can delay the time of a lot of preciousnesses, can bring a lot of inconvenience to work; When decocting Chinese medicine, flavour of a drug distribute everywhere, can smell general taste of Chinese medicine around, and impact is people's olfactory sensation and surrounding around; Drug administration process is very felt bad, and bitter medicine, under larynx, is suffered untold misery, and affects patient's mood; And long-term Chinese medicine for oral administration soup, can make human body occur some untoward reaction, as: headache, dizziness, weak, cardiopalmus, gastrointestinal upset etc.

Thereby, in one aspect of the invention, the invention provides a kind of for preventing or/and treat hypertensive pharmaceutical composition.According to embodiments of the invention, this pharmaceutical composition comprises: the Flos Chrysanthemi of 800-1200 weight portions; The Cortex Eucommiae of 0-600 weight portions; The Spica Prunellae of 300-600 weight portions; The Rhizoma Chuanxiong of 300-600 weight portions; The Folium Mori of 0-600 weight portions; The Radix Angelicae Dahuricae of 100-300 weight portions; The Cortex Moutan of 100-300 weight portions; The Fructus Viticis of 0-200 weight portions; And the Herba Asari of 50-120 weight portions.Inventor's discovery, pharmaceutical composition of the present invention can be effective to prevention or/and treatment hypertension.

According to embodiments of the invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical composition and comprise: the Flos Chrysanthemi of 900-1100 weight portions; The Cortex Eucommiae of 0-550 weight portions; The Spica Prunellae of 350-550 weight portions; The Rhizoma Chuanxiong of 350-550 weight portions; The Folium Mori of 0-550 weight portions; The Radix Angelicae Dahuricae of 150-250 weight portions; The Cortex Moutan of 150-250 weight portions; The Fructus Viticis of 0-180 weight portions; And the Herba Asari of 60-110 weight portions.Thus, this drug regimen composition formula is reasonable, and drug effect is remarkable.

According to a concrete example of the present invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical composition and comprise: the Flos Chrysanthemi of 950 weight portions; The Cortex Eucommiae of 400 weight portions; The Spica Prunellae of 400 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Folium Mori of 400 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; The Fructus Viticis of 150 weight portions; And the Herba Asari of 100 weight portions.According to another concrete example of the present invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical composition and comprise: the Flos Chrysanthemi of 1000 weight portions; The Cortex Eucommiae of 500 weight portions; The Spica Prunellae of 500 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Folium Mori of 300 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; The Fructus Viticis of 150 weight portions; And the Herba Asari of 100 weight portions.According to another concrete example of the present invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical composition and comprise: the Flos Chrysanthemi of 1000 weight portions; The Spica Prunellae of 500 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; And the Herba Asari of 100 weight portions.In one embodiment of the invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical composition and comprise: Cortex Moutan, the Fructus Viticis of 150 weight portions and the Herba Asari of 100 weight portions of the Folium Mori of the Spica Prunellae of the Flos Chrysanthemi of 900 weight portions, the Cortex Eucommiae of 400 weight portions, 400 weight portions, the Rhizoma Chuanxiong of 400 weight portions, 400 weight portions, the Radix Angelicae Dahuricae of 200 weight portions, 200 weight portions.In another embodiment of the present invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical composition and comprise: Cortex Moutan, the Fructus Viticis of 200 weight portions and the Herba Asari of 120 weight portions of the Folium Mori of the Spica Prunellae of the Flos Chrysanthemi of 1000 weight portions, the Cortex Eucommiae of 600 weight portions, 600 weight portions, the Rhizoma Chuanxiong of 500 weight portions, 600 weight portions, the Radix Angelicae Dahuricae of 250 weight portions, 250 weight portions.Thus, aforementioned pharmaceutical compositions can be with the drug effect between optimal compatibility relationship coordinating the actions of various ingredients in a prescription, thereby improves more significantly prevention or/and treat hypertensive effect.

According to embodiments of the invention, Flos Chrysanthemi is the dry capitulum of feverfew Flos Chrysanthemi Chrysanthemum morifolium Ramat.Flos Chrysanthemi is pungent sweet, and hardship is slightly cold.Return lung, Liver Channel, has except wind heat, separates furunculosis, effect of nourishing the liver to improve visual acuity.The diseases such as primary treatment affection due to external wind and heat, headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.According to embodiments of the invention, the effective ingredient of Flos Chrysanthemi is flavone compound, triterpenoid compound and volatilization wet goods.According to embodiments of the invention, Flos Chrysanthemi has treatment coronary heart disease, reduces blood pressure, prevents hyperlipidemia, antibacterial, antiviral, antiinflammatory, the anti-ageing multiple pharmacologically active of waiting for a long time.Thus, can effectively bring into play effect of blood pressure lowering.

According to embodiments of the invention, Spica Prunellae is the dry fruit ear of labiate Prunella vulgaris L..When summer, fruit ear was brownish red, gather, remove impurity, dry.Spica Prunellae is cold in nature, and sweet in the mouth, pungent, micro-hardship, return liver, and gallbladder meridian, has the effect of letting out clearly liver-fire, mass dissipating and swelling eliminating, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, cooling blood for hemostasis, cures mainly scrofula goiter, the mastalgia capsule that swells, conjunctival congestion and pain of eye.Thus, can effectively bring into play heat clearing away dissipating depression of QI eliminating stagnation, eliminating phlegm blood pressure lowering, effect of diuretic antihypertensive.

According to embodiments of the invention, Folium Mori are the dried leaves of moraceae plants Mulberry MorusalbaL..After first frost, gather, remove impurity, dry.Folium Mori are bitter sweet cold, return lung, Liver Channel.The effective ingredient of Folium Mori is for having dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, and effect of liver heat removing and eyesight improving, cures mainly anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted, pharyngalgia toothache.Thus, can effectively bring into play blood pressure lowering, hypoglycemic effect.

According to embodiments of the invention, Fructus Viticis is the dry mature fruit of Verbenaceae Vitex rotundifolia VitextrifoliaL.var.simplicifoliaCham. or wild pepper VitextrifoliaL..Gather when fruit maturation autumn, removes impurity, dries.Fructus Viticis is pungent, bitter, is slightly cold.Return bladder, liver, stomach warp, there is dispelling wind and heat pathogens, effect of the clear sharp head.Cure mainly anemopyretic cold headache, gingivitis, the many tear of conjunctival congestion, poor vision, has a dizzy spell, rheumatic arthralgia.Thus, can effectively bring into play and evacuate head wind heat, clearing eyes-improving, inducing resuscitation, effect of conditioning blood pressure.

According to embodiments of the invention, the Cortex Eucommiae is the dry bark of Eucommiaceae plant Cortex Eucommiae EucommiaulmoidesOliv..Strip 4～June, scrapes off rough bark, and " diaphoresis " to the endothelium of banking up is puce, dries.The Cortex Eucommiae is sweet, and temperature is returned liver, kidney channel, has invigorating the liver and kidney, strengthening bone and muscle, and antiabortive effect, cures mainly lumbago flaccidity of the lower limbs, vaginal bleeding during pregnancy frequent micturition, deficiency of the liver and kindey, soreness of waist and knee joint, muscles and bones is unable, has a dizzy spell, blood leaking in gestation, frequent fetal movement.Thus, can liver and kidney tonifying, effectively bring into play effect of blood pressure lowering.

According to embodiments of the invention, Rhizoma Chuanxiong is the dry rhizome of samphire Rhizoma Chuanxiong Ligusticum chuanxiong.The pungent temperature of Rhizoma Chuanxiong, returns liver, gallbladder, pericardium channel, has promoting blood circulation to restore menstrual flow, and effect of wind-expelling pain-stopping, cures mainly menoxenia, headache, sternal rib pain, arthralgia pain contracture carbuncle.In pharmaceutical composition of the present invention, Rhizoma Chuanxiong promoting blood circulation to restore menstrual flow, wind-expelling pain-stopping, to headache, hypertension has good effect.

According to embodiments of the invention, the Radix Angelicae Dahuricae is samphire Radix Angelicae Dahuricae Angelica dahurica(Fisch.ex Hoffm.) Benth.et Hook.f. or Radix angelicae dahuricae Angelica dahurica(Fisch.ex Hoffm.) Benth.et Hook.f.var.formosana(Boiss.) dry root of Shan et Yuan.When leaf is yellow between summer, autumn, excavate, remove fibrous root and silt, dry or cold drying.The Radix Angelicae Dahuricae is pungent, warm, returns lung, stomach, large intestine channel, has and delivers, and dispels the wind, and victory is wet, invigorate blood circulation, and pain relieving, effect of evacuation of pus, cures mainly flu, headache feeling of fullness in the head, nasal sinusitis, leucorrhea with red and white discharge, the swollen skin infection of pain.In pharmaceutical composition of the present invention, the Radix Angelicae Dahuricae is mainly brought into play clearing away heat and expelling pathogen in the exterior, dispelling wind and heat pathogens, and expelling wind and activating blood circulation, promotes that QI and blood is unobstructed, regulates effect of blood pressure.

According to embodiments of the invention, Cortex Moutan is the dry root bark of cohosh Cortex Moutan Tree peony bark, contains paeonol, paeonoside etc.Cortex Moutan, bitter in the mouth, pungent cold nature, GUIXIN, Liver and kidney warp, has clearing away heat and cooling blood, and effect of promoting blood circulation to remove blood stasis, cures mainly, and sends out speckle infantile convulsion, tells nosebleed hematochezia, amenorrhea and mass in the abdomen, enterodynia, thus, can bring into play obvious hypotensive effect.

According to embodiments of the invention, Herba Asari is the dry herb of aristolochiaceae plant Herba Asari Asarum heterotropoides Fr.Schmidt var.mandshur-icum (Maxim.) Kitag., Seoul Herba Asari Asarum sieboldii Miq.var.seoulense Nakai or magnificent Herba Asari Asarum sieboldii Miq..Summer fructescence or early autumn excavate, and remove silt, dry in the shade.Herba Asari is pungent, warm, and GUIXIN, lung, kidney channel have loose wind cold relieving, warming the lung to resolve fluid-retention, and effect of wind-expelling pain-stopping, cures mainly typhoid fever, headache, phlegm retention cough with asthma.Rheumatic arthralgia, nasal sinusitis toothache.In pharmaceutical composition of the present invention, evacuation migratory arthralgia can be effectively brought into play, and the headache that hypertension causes can be eliminated, help blood pressure lowering and improve effect of symptom.

In another aspect of this invention, the invention provides one for preventing or/and treat hypertensive medicine.According to embodiments of the invention, this pharmaceutical pack contains: the Flos Chrysanthemi of 800-1200 weight portions; The Cortex Eucommiae of 0-600 weight portions; The Spica Prunellae of 300-600 weight portions; The Rhizoma Chuanxiong of 300-600 weight portions; The Folium Mori of 0-600 weight portions; The Radix Angelicae Dahuricae of 100-300 weight portions; The Cortex Moutan of 100-300 weight portions; The Fructus Viticis of 0-200 weight portions; And the Herba Asari of 50-120 weight portions.Inventor finds, of the present invention for prevention or/and to treat hypertensive compatibility of drugs reasonable, drug effect is remarkable, and can not have side effects.

According to embodiments of the invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical pack and contain: the Flos Chrysanthemi of 900-1100 weight portions; The Cortex Eucommiae of 0-550 weight portions; The Spica Prunellae of 350-550 weight portions; The Rhizoma Chuanxiong of 350-550 weight portions; The Folium Mori of 0-550 weight portions; The Radix Angelicae Dahuricae of 150-250 weight portions; The Cortex Moutan of 150-250 weight portions; The Fructus Viticis of 0-180 weight portions; And the Herba Asari of 60-110 weight portions.Thus, pharmaceutical formulation of the present invention is reasonable, and drug effect is better, and there is no untoward reaction.

According to a concrete example of the present invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical pack and contain: the Flos Chrysanthemi of 950 weight portions; The Cortex Eucommiae of 400 weight portions; The Spica Prunellae of 400 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Folium Mori of 400 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; The Fructus Viticis of 150 weight portions; And the Herba Asari of 100 weight portions.According to another concrete example of the present invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical pack and contain: the Flos Chrysanthemi of 1000 weight portions; The Cortex Eucommiae of 500 weight portions; The Spica Prunellae of 500 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Folium Mori of 300 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; The Fructus Viticis of 150 weight portions; And the Herba Asari of 100 weight portions.According to another concrete example of the present invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical pack and contain: the Flos Chrysanthemi of 1000 weight portions; The Spica Prunellae of 500 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; And the Herba Asari of 100 weight portions.In one embodiment of the invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical pack and contain: Cortex Moutan, the Fructus Viticis of 150 weight portions and the Herba Asari of 100 weight portions of the Folium Mori of the Spica Prunellae of the Flos Chrysanthemi of 900 weight portions, the Cortex Eucommiae of 400 weight portions, 400 weight portions, the Rhizoma Chuanxiong of 400 weight portions, 400 weight portions, the Radix Angelicae Dahuricae of 200 weight portions, 200 weight portions.In another embodiment of the present invention, above-mentioned for prevention or/and treat hypertensive pharmaceutical pack and contain: Cortex Moutan, the Fructus Viticis of 200 weight portions and the Herba Asari of 120 weight portions of the Folium Mori of the Spica Prunellae of the Flos Chrysanthemi of 1000 weight portions, the Cortex Eucommiae of 600 weight portions, 600 weight portions, the Rhizoma Chuanxiong of 500 weight portions, 600 weight portions, the Radix Angelicae Dahuricae of 250 weight portions, 250 weight portions.Thus, said medicine can be with the drug effect between optimal compatibility relationship coordinating the actions of various ingredients in a prescription, thereby improves more significantly prevention or/and treat hypertensive effect.

According to embodiments of the invention, above-mentioned for preventing or/and treat hypertensive medicine and provide with the form of medicated pillow.Thus, the effectively generation of prophylaxis of hypertension, reduce hypertensive sickness rate, can also reduce and remove the impact that hyperpietic's enalapril meleate brings health, and easy to use, free from environmental pollution, hyperpietic only needs to rest the head in bed every night medicated pillow, just can reduce blood pressure, make blood pressure normally stable.In addition, medicated pillow of the present invention is simple to operate, and the natural herbal that only need prepare mixes in proportion, dries, pulverizes and packs by weight pillow into, and equipment needed thereby is few, utilizes space little, and without any side effect.

It should be noted that, the principle of medicated pillow of the present invention performance drug effect is as follows: hyperpietic's medicated pillow of resting the head in bed every night, medicine ion can be invaded patient's head and each corresponding acupuncture point and the skin of shoulder, thereby plays a role.Wherein, main acupuncture point has: Tianzhu point, and Fengchi acupoint, temple, Baihui acupoint, DAZHUI acupoint, Jianjing point, high pressure is attacked a vital point.Ear has: have sharp ears cave, and blood pressure lowering ditch cave etc., patient's medicated pillow of sleeping every night, the medicinal herbs in medicated pillow are all at the skin that directly acts on these acupuncture points and head and shoulder, give full play to effect separately after these acupuncture points are upset.As; Baihui acupoint: be health care and the cave of wanting of controlling wind, have the turbid descending recuperating depleted YANG, inducing resuscitation, regulating YIN and YANG, suppressing the hyperactive liver to relieve the wind syndrome, effect of conditioning blood pressure.Fengchi acupoint: energy expelling pathogenic wind from the body surface, clearing eyes-improving.Jianjing point: the resolving depression that can stimulate the menstrual flow, eliminate phlegm for resuscitation, heat clearing away eliminating stagnation, sending down the abnormal ascending QI adjust blood pressure.Have sharp ears cave: energy clearing away heat to improve acuity of vision, promoting blood circulation to remove obstruction in the collateral, anti-inflammatory analgetic, controls headache, and hypertension etc. have good effect.Blood pressure lowering ditch cave: there are the internal organs of tune negative and positive, conducting blood to flow downwards, suppressing the hyperactive liver purges heat, effect of blood pressure lowering.DAZHUI acupoint: have the dredging collateral of inducing sweat, regulate blood pressure.Blood pressure is attacked a vital point: can clearing away heat and expelling pathogen in the exterior, promote that QI and blood is unobstructed, and regulate blood pressure, prevent and treat hypertension and hypotensive generation.Thus, the medicinal herbs in medicated pillow invade in these corresponding acupuncture points and skin, make effectively performance effect separately of these acupuncture points, thereby reach the object for the treatment of and prophylaxis of hypertension.Meanwhile, medicinal herbs molecular diffusion, makes patient in the time sleeping medicated pillow, smells the abnormal smells from the patient of medicinal herbs, thereby has more effectively brought into play the effect of medicated pillow blood pressure lowering.

In one side more of the present invention, the present invention also provides a kind of method of preparing medicine noted earlier.According to embodiments of the invention, the method comprises: provide medicinal herbs according to following ratio: the Flos Chrysanthemi of 800-1200 weight portions; The Cortex Eucommiae of 0-600 weight portions; The Spica Prunellae of 300-600 weight portions; The Rhizoma Chuanxiong of 300-600 weight portions; The Folium Mori of 0-600 weight portions; The Radix Angelicae Dahuricae of 100-300 weight portions; The Cortex Moutan of 100-300 weight portions; The Fructus Viticis of 0-200 weight portions; And the Herba Asari of 50-120 weight portions, to obtain medicinal herbs mixture; Described medicinal herbs mixture is carried out to pulverization process; And using the medicinal herbs mixture of obtained process pulverization process as described prevention or/and treat hypertensive medicine.Inventor finds, the method is simple to operate, rapid and convenient, and the medicine obtaining can pack pillow core into and make medicated pillow, hyperpietic's medicated pillow of resting the head in bed every night can reach the object of blood pressure lowering, the misery of having avoided the required manpower of decocting herb, time and patient to take medicine, and be free from side effects.

According to embodiments of the invention, provide medicinal herbs according to following ratio: the Flos Chrysanthemi of 900-1100 weight portions; The Cortex Eucommiae of 0-550 weight portions; The Spica Prunellae of 350-550 weight portions; The Rhizoma Chuanxiong of 350-550 weight portions; The Folium Mori of 0-550 weight portions; The Radix Angelicae Dahuricae of 150-250 weight portions; The Cortex Moutan of 150-250 weight portions; The Fructus Viticis of 0-180 weight portions; And the Herba Asari of 60-110 weight portions.Thus, the compatibility of drugs preparing is reasonable, between all medicines, has synergism, and prevention is or/and to treat hypertensive effect remarkable, not untoward reaction.

According to a concrete example of the present invention, provide medicinal herbs according to following ratio: the Flos Chrysanthemi of 950 weight portions; The Cortex Eucommiae of 400 weight portions; The Spica Prunellae of 400 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Folium Mori of 400 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; The Fructus Viticis of 150 weight portions; And the Herba Asari of 100 weight portions.According to another concrete example of the present invention, provide medicinal herbs according to following ratio: the Flos Chrysanthemi of 1000 weight portions; The Cortex Eucommiae of 500 weight portions; The Spica Prunellae of 500 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Folium Mori of 300 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; The Fructus Viticis of 150 weight portions; And the Herba Asari of 100 weight portions.According to another concrete example of the present invention, provide medicinal herbs according to following ratio: the Flos Chrysanthemi of 1000 weight portions; The Spica Prunellae of 500 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; And the Herba Asari of 100 weight portions.In one embodiment of the invention, provide medicinal herbs according to following ratio: Cortex Moutan, the Fructus Viticis of 150 weight portions and the Herba Asari of 100 weight portions of the Folium Mori of the Spica Prunellae of the Flos Chrysanthemi of 900 weight portions, the Cortex Eucommiae of 400 weight portions, 400 weight portions, the Rhizoma Chuanxiong of 400 weight portions, 400 weight portions, the Radix Angelicae Dahuricae of 200 weight portions, 200 weight portions.In another embodiment of the present invention, provide medicinal herbs according to following ratio: Cortex Moutan, the Fructus Viticis of 200 weight portions and the Herba Asari of 120 weight portions of the Folium Mori of the Spica Prunellae of the Flos Chrysanthemi of 1000 weight portions, the Cortex Eucommiae of 600 weight portions, 600 weight portions, the Rhizoma Chuanxiong of 500 weight portions, 600 weight portions, the Radix Angelicae Dahuricae of 250 weight portions, 250 weight portions.Thus, the medicine preparing can be with the drug effect between optimal compatibility relationship coordinating the actions of various ingredients in a prescription, thereby improves more significantly prevention or/and treat hypertensive effect.

According to embodiments of the invention, described pulverization process is that the granularity that described medicinal herbs mixture is crushed to Flos Chrysanthemi is 100 orders, Cortex Eucommiae granularity is 100 orders, Spica Prunellae granularity is 100 orders, and Rhizoma Chuanxiong granularity is 100 orders, and Folium Mori granularity is 100 orders, Radix Angelicae Dahuricae granularity is 150 orders, Cortex Moutan granularity is 150 orders, and Fructus Viticis granularity is 100 orders, and Herba Asari granularity is 200 orders.Thus, be conducive to the performance of drug effect.

According to embodiments of the invention, the method for preparing foregoing medicine further comprises: the described medicinal herbs mixture through pulverization process is packed in pillow core, make medicated pillow.Thus, the effectively generation of prophylaxis of hypertension, reduce hypertensive sickness rate, can also reduce and remove the impact that hyperpietic's enalapril meleate brings health, and easy to use, free from environmental pollution, hyperpietic only needs to rest the head in bed every night medicated pillow, just can reduce blood pressure, make blood pressure normally stable, in addition, simple to operate, the natural herbal that only need prepare mixes in proportion, dries, pulverizes and packs by weight pillow into, and equipment needed thereby is few, utilize space little, and without any side effect.

Additional aspect of the present invention and advantage in the following description part provide, and part will become obviously from the following description, or recognize by practice of the present invention.

Detailed description of the invention

Describe embodiments of the invention below in detail.Embodiment described below is exemplary, only for explaining the present invention, and can not be interpreted as limitation of the present invention.Unreceipted concrete technology or condition in embodiment, according to the described technology of the document in this area or condition or carry out according to product description.The unreceipted person of production firm of agents useful for same or instrument, being can be by the conventional products of commercial acquisition.

Embodiment 1

Take the Flos Chrysanthemi of 800 weight portions, the Cortex Eucommiae of 300 weight portions, the Spica Prunellae of 300 weight portions, the Rhizoma Chuanxiong of 300 weight portions, the Folium Mori of 300 weight portions, the Radix Angelicae Dahuricae of 100 weight portions, Cortex Moutan, the Fructus Viticis of 100 weight portions and the Herba Asari of 50 weight portions of 100 weight portions, then, obtained medicinal herbs mixture is carried out to pulverization process, the granularity that obtains Flos Chrysanthemi, the Cortex Eucommiae, Spica Prunellae, Rhizoma Chuanxiong, Folium Mori and Fructus Viticis is 100 orders, the granularity of the Radix Angelicae Dahuricae and Cortex Moutan is 150 orders, the granularity of Herba Asari is 200 object medicinal herbs mixture, packed into pillow core, made medicated pillow A.

Embodiment 2

Take the Flos Chrysanthemi of 1200 weight portions, the Cortex Eucommiae of 600 weight portions, the Spica Prunellae of 600 weight portions, the Rhizoma Chuanxiong of 600 weight portions, the Folium Mori of 600 weight portions, the Radix Angelicae Dahuricae of 300 weight portions, Cortex Moutan, the Fructus Viticis of 200 weight portions and the Herba Asari of 100 weight portions of 300 weight portions, then, obtained medicinal herbs mixture is carried out to pulverization process, the granularity that obtains Flos Chrysanthemi, the Cortex Eucommiae, Spica Prunellae, Rhizoma Chuanxiong, Folium Mori and Fructus Viticis is 100 orders, the granularity of the Radix Angelicae Dahuricae and Cortex Moutan is 150 orders, the granularity of Herba Asari is 200 object medicinal herbs mixture, packed into pillow core, made medicated pillow B.

Embodiment 3

Take the Flos Chrysanthemi of 900 weight portions, the Cortex Eucommiae of 350 weight portions, the Spica Prunellae of 350 weight portions, the Rhizoma Chuanxiong of 350 weight portions, the Folium Mori of 350 weight portions, the Radix Angelicae Dahuricae of 150 weight portions, Cortex Moutan, the Fructus Viticis of 120 weight portions and the Herba Asari of 60 weight portions of 150 weight portions, then, obtained medicinal herbs mixture is carried out to pulverization process, the granularity that obtains Flos Chrysanthemi, the Cortex Eucommiae, Spica Prunellae, Rhizoma Chuanxiong, Folium Mori and Fructus Viticis is 100 orders, the granularity of the Radix Angelicae Dahuricae and Cortex Moutan is 150 orders, the granularity of Herba Asari is 200 object medicinal herbs mixture, packed into pillow core, made medicated pillow C.

Embodiment 4

Take the Flos Chrysanthemi of 1100 weight portions, the Cortex Eucommiae of 550 weight portions, the Spica Prunellae of 550 weight portions, the Rhizoma Chuanxiong of 550 weight portions, the Folium Mori of 550 weight portions, the Radix Angelicae Dahuricae of 250 weight portions, Cortex Moutan, the Fructus Viticis of 180 weight portions and the Herba Asari of 110 weight portions of 250 weight portions, then, obtained medicinal herbs mixture is carried out to pulverization process, the granularity that obtains Flos Chrysanthemi, the Cortex Eucommiae, Spica Prunellae, Rhizoma Chuanxiong, Folium Mori and Fructus Viticis is 100 orders, the granularity of the Radix Angelicae Dahuricae and Cortex Moutan is 150 orders, the granularity of Herba Asari is 200 object medicinal herbs mixture, packed into pillow core, made medicated pillow D.

Embodiment 5

Take the Flos Chrysanthemi of 1000 weight portions, the Cortex Eucommiae of 500 weight portions, the Spica Prunellae of 500 weight portions, the Rhizoma Chuanxiong of 400 weight portions, the Folium Mori of 300 weight portions, the Radix Angelicae Dahuricae of 200 weight portions, Cortex Moutan, the Fructus Viticis of 150 weight portions and the Herba Asari of 100 weight portions of 200 weight portions, then, obtained medicinal herbs mixture is carried out to pulverization process, the granularity that obtains Flos Chrysanthemi, the Cortex Eucommiae, Spica Prunellae, Rhizoma Chuanxiong, Folium Mori and Fructus Viticis is 100 orders, the granularity of the Radix Angelicae Dahuricae and Cortex Moutan is 150 orders, the granularity of Herba Asari is 200 object medicinal herbs mixture, packed into pillow core, made medicated pillow E.

Embodiment 6

Take the Flos Chrysanthemi of 1000 weight portions, the Spica Prunellae of 500 weight portions, the Rhizoma Chuanxiong of 400 weight portions, the Radix Angelicae Dahuricae, the Cortex Moutan of 200 weight portions and the Herba Asari of 100 weight portions of 200 weight portions, then, obtained medicinal herbs mixture is carried out to pulverization process, the granularity that obtains Flos Chrysanthemi, the Cortex Eucommiae, Spica Prunellae, Rhizoma Chuanxiong, Folium Mori and Fructus Viticis is 100 orders, the granularity of the Radix Angelicae Dahuricae and Cortex Moutan is 150 orders, the granularity of Herba Asari is 200 object medicinal herbs mixture, is packed into pillow core, makes medicated pillow F.

Embodiment 7

Take the Flos Chrysanthemi of 900 weight portions, the Cortex Eucommiae of 400 weight portions, the Spica Prunellae of 400 weight portions, the Rhizoma Chuanxiong of 400 weight portions, the Folium Mori of 400 weight portions, the Radix Angelicae Dahuricae of 200 weight portions, Cortex Moutan, the Fructus Viticis of 150 weight portions and the Herba Asari of 100 weight portions of 200 weight portions, then, obtained medicinal herbs mixture is carried out to pulverization process, the granularity that obtains Flos Chrysanthemi, the Cortex Eucommiae, Spica Prunellae, Rhizoma Chuanxiong, Folium Mori and Fructus Viticis is 100 orders, the granularity of the Radix Angelicae Dahuricae and Cortex Moutan is 150 orders, the granularity of Herba Asari is 200 object medicinal herbs mixture, packed into pillow core, made medicated pillow G.

Embodiment 8

Take the Flos Chrysanthemi of 1000 weight portions, the Cortex Eucommiae of 600 weight portions, the Spica Prunellae of 600 weight portions, the Rhizoma Chuanxiong of 500 weight portions, the Folium Mori of 600 weight portions, the Radix Angelicae Dahuricae of 250 weight portions, Cortex Moutan, the Fructus Viticis of 200 weight portions and the Herba Asari of 120 weight portions of 250 weight portions, then, obtained medicinal herbs mixture is carried out to pulverization process, the granularity that obtains Flos Chrysanthemi, the Cortex Eucommiae, Spica Prunellae, Rhizoma Chuanxiong, Folium Mori and Fructus Viticis is 100 orders, the granularity of the Radix Angelicae Dahuricae and Cortex Moutan is 150 orders, the granularity of Herba Asari is 200 object medicinal herbs mixture, packed into pillow core, made medicated pillow H.

Embodiment 9

The medicated pillow A preparing below by human body experimental evaluation embodiment 1,5-8 on probation, the antihypertensive effect of E-H, specific as follows:

Tested patient 5 People, wherein, patient 1 is women, 46 years old, suffer from hypertension (160-170/100-110mmHg) 4 years, informal dress depressor control hypertension, private prosecution has headache at ordinary times, feel sick, the disease such as To Be Protected from Heat, insomnia and dreamful sleep, have a blood test and press 160/100mmHg, Chest X-rays: cardiopulmonary no abnormality seen, electrocardiogram is without abnormal change, blood fat is not high, edema that lower limb are slight, and enlarged tongue color is light, white and thin fur, stringy and thready pulse, is diagnosed as constitutional blood pressure; Patient 2 is women, 58 years old, suffers from hypertension more than 6 years, multi-treatment poor effect, the state of an illness day by day increases the weight of, and floating red, the eyelid duskiness of dizzy, complexion, headache, insomnia and dreamful sleep, night, there were indentation, white and thin fur, wiry and frequent pulse in many urine, red tongue limit, had a blood test and pressed 190/120mmHg; Patient 3 is women, 68 years old, and suffer from hypertension and have a surplus for 8 years, take for a long time depressor, but still at 180/120mmHg; Patient 4 is male, 53 years old, suffers from headaches, dizziness more than 10 years, over more than 10 year, patient's hypertension continues at 170-180/110-120mmHg, vexed with the heart, tinnitus, dysphoria with feverish sensation in the chest palms and soles, cardiopalmus, the diseases such as insomnia, red tongue, white and thin fur, stringy and thready pulse, sinus rhythm: 85 beats/min, Chest X-rays: aortic arch is widened, examination of ocular fundus no abnormality seen is the hypertension II phase; Patient 5 is male, and 55 years old, patient was once diagnosed as essential hypertension at examination in hospital, and blood pressure is 200/130mmHg, informal dress depressor, and poor effect, private prosecution was suffered from hypertension more than 4 years, often had giddy, tinnitus, blurred vision, uncomfortable in chest, cardiopalmus, brothers' shake sometimes.

The medicated pillow that the above-described embodiment of resting the head on while making patient 1-5 sleeping at night prepares, patient 1 uses medicated pillow A, and patient 2 uses medicated pillow E, and patient 3 uses medicated pillow F, and patient 4 uses medicated pillow G, and patient 5 uses medicated pillow H.Use after a period of time, observe result of use.

Experimental result is as follows: patient 1 uses medicated pillow after two months, and blood pressure is down to 130/90mmHg, withdraws gradually depressor after three months, and blood pressure is down to normal range, and symptom is also felt and is clearly better simultaneously, has no hypertension after half a year; Patient 2 uses medicated pillow after 3 months, and blood pressure is down to 160/100mmHg, and all diseases obviously alleviate, and withdraw depressor gradually, and after 4 months, blood pressure is down to 150/90mmHg, and all diseases disappear, and it is normal that blood pressure recovers, and follows up a case by regular visits to and within 1 year, have no recurrence; Patient 3 is using after medicated pillow one and a half months, and blood pressure is down to 150/90mmHg, after 3 months, withdraws gradually depressor, and blood pressure is without the phenomenon increasing; Patient 4 uses after two first quarter moons of medicated pillow, and blood pressure is down to 150/100mmHg, and after three first quarter moons, blood pressure is down to 130/90mmHg, and subjective symptoms disappears, and withdraws gradually depressor, and blood pressure is repeatedly checked, and all, within normal range, has no rising phenomenon; Patient 5 uses medicated pillow after 2 months, and blood pressure is down to 180/110mmHg, and after three first quarter moons, blood pressure is down to 145/90mmHg, and withdraws depressor gradually, and after half a year, blood pressure is always normally stable.The above results shows, pharmaceutical composition of the present invention has significant prevention or/and treat hypertensive effect.

In the description of this description, the description of reference term " embodiment ", " some embodiment ", " example ", " concrete example " or " some examples " etc. means to be contained at least one embodiment of the present invention or example in conjunction with specific features, structure, material or the feature of this embodiment or example description.In this manual, the schematic statement of above-mentioned term is not necessarily referred to identical embodiment or example.And specific features, structure, material or the feature of description can be with suitable mode combination in any one or more embodiment or example.

Although illustrated and described embodiments of the invention above, be understandable that, above-described embodiment is exemplary, can not be interpreted as limitation of the present invention, those of ordinary skill in the art can change above-described embodiment within the scope of the invention in the situation that not departing from principle of the present invention and aim, amendment, replacement and modification.

Claims

For prevention or/and treat a hypertensive pharmaceutical composition, it is characterized in that, comprise:

The Flos Chrysanthemi of 800-1200 weight portions;

The Cortex Eucommiae of 0-600 weight portions;

The Spica Prunellae of 300-600 weight portions;

The Rhizoma Chuanxiong of 300-600 weight portions;

The Folium Mori of 0-600 weight portions;

The Radix Angelicae Dahuricae of 100-300 weight portions;

The Cortex Moutan of 100-300 weight portions;

The Fructus Viticis of 0-200 weight portions; And

The Herba Asari of 50-120 weight portions.
2. pharmaceutical composition according to claim 1, is characterized in that, comprises:

The Flos Chrysanthemi of 900-1100 weight portions;

The Cortex Eucommiae of 0-550 weight portions;

The Spica Prunellae of 350-550 weight portions;

The Rhizoma Chuanxiong of 350-550 weight portions;

The Folium Mori of 0-550 weight portions;

The Radix Angelicae Dahuricae of 150-250 weight portions;

The Cortex Moutan of 150-250 weight portions;

The Fructus Viticis of 0-180 weight portions; And

The Herba Asari of 60-110 weight portions.
3. pharmaceutical composition according to claim 2, is characterized in that, comprises:

The Flos Chrysanthemi of 950 weight portions;

The Cortex Eucommiae of 400 weight portions;

The Spica Prunellae of 400 weight portions;

The Rhizoma Chuanxiong of 400 weight portions;

The Folium Mori of 400 weight portions;

The Radix Angelicae Dahuricae of 200 weight portions;

The Cortex Moutan of 200 weight portions;

The Fructus Viticis of 150 weight portions; And

The Herba Asari of 100 weight portions,

Optionally, described pharmaceutical composition comprises:

The Flos Chrysanthemi of 1000 weight portions;

The Cortex Eucommiae of 500 weight portions;

The Spica Prunellae of 500 weight portions;

The Rhizoma Chuanxiong of 400 weight portions;

The Folium Mori of 300 weight portions;

The Radix Angelicae Dahuricae of 200 weight portions;

The Cortex Moutan of 200 weight portions;

The Fructus Viticis of 150 weight portions; And

The Herba Asari of 100 weight portions,

Optionally, described pharmaceutical composition comprises:

The Flos Chrysanthemi of 1000 weight portions;

The Spica Prunellae of 500 weight portions;

The Rhizoma Chuanxiong of 400 weight portions;

The Radix Angelicae Dahuricae of 200 weight portions;

The Cortex Moutan of 200 weight portions; And

The Herba Asari of 100 weight portions,

Optionally, described pharmaceutical composition comprises:

The Flos Chrysanthemi of 900 weight portions;

The Cortex Eucommiae of 400 weight portions;

The Spica Prunellae of 400 weight portions;

The Rhizoma Chuanxiong of 400 weight portions;

The Folium Mori of 400 weight portions;

The Radix Angelicae Dahuricae of 200 weight portions;

The Cortex Moutan of 200 weight portions;

The Fructus Viticis of 150 weight portions; And

The Herba Asari of 100 weight portions,

Optionally, described pharmaceutical composition comprises:

The Flos Chrysanthemi of 1000 weight portions;

The Cortex Eucommiae of 600 weight portions;

The Spica Prunellae of 600 weight portions;

The Rhizoma Chuanxiong of 500 weight portions;

The Folium Mori of 600 weight portions;

The Radix Angelicae Dahuricae of 250 weight portions;

The Cortex Moutan of 250 weight portions;

The Fructus Viticis of 200 weight portions; And

The Herba Asari of 120 weight portions.
For prevention or/and treat a hypertensive medicine, it is characterized in that, comprise:

The Flos Chrysanthemi of 800-1200 weight portions;

The Cortex Eucommiae of 0-600 weight portions;

The Spica Prunellae of 300-600 weight portions;

The Rhizoma Chuanxiong of 300-600 weight portions;

The Folium Mori of 0-600 weight portions;

The Radix Angelicae Dahuricae of 100-300 weight portions;

The Cortex Moutan of 100-300 weight portions;

The Fructus Viticis of 0-200 weight portions; And

The Herba Asari of 50-120 weight portions.
5. medicine according to claim 4, is characterized in that, comprises:

The Flos Chrysanthemi of 900-1100 weight portions;

The Cortex Eucommiae of 0-550 weight portions;

The Spica Prunellae of 350-550 weight portions;

The Rhizoma Chuanxiong of 350-550 weight portions;

The Folium Mori of 0-550 weight portions;

The Radix Angelicae Dahuricae of 150-250 weight portions;

The Cortex Moutan of 150-250 weight portions;

The Fructus Viticis of 0-180 weight portions; And

The Herba Asari of 60-110 weight portions.
6. medicine according to claim 4, is characterized in that, comprises:

The Flos Chrysanthemi of 950 weight portions;

The Cortex Eucommiae of 400 weight portions;

The Spica Prunellae of 400 weight portions;

The Rhizoma Chuanxiong of 400 weight portions;

The Folium Mori of 400 weight portions;

The Radix Angelicae Dahuricae of 200 weight portions;

The Cortex Moutan of 200 weight portions;

The Fructus Viticis of 150 weight portions; And

The Herba Asari of 100 weight portions,

Optionally, described pharmaceutical pack contains:

The Flos Chrysanthemi of 1000 weight portions;

The Cortex Eucommiae of 500 weight portions;

The Spica Prunellae of 500 weight portions;

The Rhizoma Chuanxiong of 400 weight portions;

The Folium Mori of 300 weight portions;

The Radix Angelicae Dahuricae of 200 weight portions;

The Cortex Moutan of 200 weight portions;

The Fructus Viticis of 150 weight portions; And

The Herba Asari of 100 weight portions,

Optionally, described pharmaceutical pack contains:

The Flos Chrysanthemi of 1000 weight portions;

The Spica Prunellae of 500 weight portions;

The Rhizoma Chuanxiong of 400 weight portions;

The Radix Angelicae Dahuricae of 200 weight portions;

The Cortex Moutan of 200 weight portions; And

The Herba Asari of 100 weight portions,

Optionally, described pharmaceutical pack contains:

The Flos Chrysanthemi of 900 weight portions;

The Cortex Eucommiae of 400 weight portions;

The Spica Prunellae of 400 weight portions;

The Rhizoma Chuanxiong of 400 weight portions;

The Folium Mori of 400 weight portions;

The Radix Angelicae Dahuricae of 200 weight portions;

The Cortex Moutan of 200 weight portions;

The Fructus Viticis of 150 weight portions; And

The Herba Asari of 100 weight portions,

Optionally, described pharmaceutical pack contains:

The Flos Chrysanthemi of 1000 weight portions;

The Cortex Eucommiae of 600 weight portions;

The Spica Prunellae of 600 weight portions;

The Rhizoma Chuanxiong of 500 weight portions;

The Folium Mori of 600 weight portions;

The Radix Angelicae Dahuricae of 250 weight portions;

The Cortex Moutan of 250 weight portions;

The Fructus Viticis of 200 weight portions; And

The Herba Asari of 120 weight portions.
7. medicine according to claim 4, is characterized in that, described medicine provides with the form of medicated pillow.
8. a method of preparing medicine described in claim 4～7 any one, is characterized in that, comprising:

Provide medicinal herbs according to following ratio: the Flos Chrysanthemi of 800-1200 weight portions; The Cortex Eucommiae of 0-600 weight portions; The Spica Prunellae of 300-600 weight portions; The Rhizoma Chuanxiong of 300-600 weight portions; The Folium Mori of 0-600 weight portions; The Radix Angelicae Dahuricae of 100-300 weight portions; The Cortex Moutan of 100-300 weight portions; The Fructus Viticis of 0-200 weight portions; And the Herba Asari of 50-120 weight portions, to obtain medicinal herbs mixture;

Described medicinal herbs mixture is carried out to pulverization process;

Using the medicinal herbs mixture of obtained process pulverization process as described prevention or/and treat hypertensive medicine.
9. method according to claim 8, is characterized in that, provides medicinal herbs according to following ratio: the Flos Chrysanthemi of 900-1100 weight portions; The Cortex Eucommiae of 0-550 weight portions; The Spica Prunellae of 350-550 weight portions; The Rhizoma Chuanxiong of 350-550 weight portions; The Folium Mori of 0-550 weight portions; The Radix Angelicae Dahuricae of 150-250 weight portions; The Cortex Moutan of 150-250 weight portions; The Fructus Viticis of 0-180 weight portions; And the Herba Asari of 60-110 weight portions.
10. method according to claim 9, is characterized in that, provides medicinal herbs according to following ratio: the Flos Chrysanthemi of 950 weight portions; The Cortex Eucommiae of 400 weight portions; The Spica Prunellae of 400 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Folium Mori of 400 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; The Fructus Viticis of 150 weight portions; And the Herba Asari of 100 weight portions,

Optionally, provide medicinal herbs according to following ratio: the Flos Chrysanthemi of 1000 weight portions; The Cortex Eucommiae of 500 weight portions; The Spica Prunellae of 500 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Folium Mori of 300 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; The Fructus Viticis of 150 weight portions; And the Herba Asari of 100 weight portions,

Optionally, provide medicinal herbs according to following ratio: the Flos Chrysanthemi of 1000 weight portions; The Spica Prunellae of 500 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; And the Herba Asari of 100 weight portions,

Optionally, provide medicinal herbs according to following ratio: the Flos Chrysanthemi of 900 weight portions; The Cortex Eucommiae of 400 weight portions; The Spica Prunellae of 400 weight portions; The Rhizoma Chuanxiong of 400 weight portions; The Folium Mori of 400 weight portions; The Radix Angelicae Dahuricae of 200 weight portions; The Cortex Moutan of 200 weight portions; The Fructus Viticis of 150 weight portions; And the Herba Asari of 100 weight portions,

Optionally, provide medicinal herbs according to following ratio: the Flos Chrysanthemi of 1000 weight portions; The Cortex Eucommiae of 600 weight portions; The Spica Prunellae of 600 weight portions; The Rhizoma Chuanxiong of 500 weight portions; The Folium Mori of 600 weight portions; The Radix Angelicae Dahuricae of 250 weight portions; The Cortex Moutan of 250 weight portions; The Fructus Viticis of 200 weight portions; And the Herba Asari of 120 weight portions.
11. methods according to claim 8, it is characterized in that, described pulverization process is that the granularity that described medicinal herbs mixture is crushed to Flos Chrysanthemi is 100 orders, and the granularity of the Cortex Eucommiae is 100 orders, and the granularity of Spica Prunellae is 100 orders, the granularity of Rhizoma Chuanxiong is 100 orders, the granularity of Folium Mori is 100 orders, and the granularity of the Radix Angelicae Dahuricae is 150 orders, and the granularity of Cortex Moutan is 150 orders, the granularity of Fructus Viticis is 100 orders, and the granularity of Herba Asari is 200 orders.
12. methods according to claim 8, is characterized in that, further comprise:

The described medicinal herbs mixture through pulverization process is packed in pillow core, make medicated pillow.