CN106309155A - Slow-release biological enzyme gel composition for shaving whiskers and cleaning face - Google Patents

Slow-release biological enzyme gel composition for shaving whiskers and cleaning face Download PDF

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Publication number
CN106309155A
CN106309155A CN201610881257.1A CN201610881257A CN106309155A CN 106309155 A CN106309155 A CN 106309155A CN 201610881257 A CN201610881257 A CN 201610881257A CN 106309155 A CN106309155 A CN 106309155A
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CN
China
Prior art keywords
gellan gum
composition weight
compound
gel
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610881257.1A
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Chinese (zh)
Inventor
谷志静
田俊
赵泽华
洪武贤
李洪波
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LAF INTERNATIONAL GROUP Ltd
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LAF INTERNATIONAL GROUP Ltd
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Publication date
Application filed by LAF INTERNATIONAL GROUP Ltd filed Critical LAF INTERNATIONAL GROUP Ltd
Priority to CN201610881257.1A priority Critical patent/CN106309155A/en
Publication of CN106309155A publication Critical patent/CN106309155A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/463Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/008Preparations for oily skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides a compound enzyme no-clean shampoo composition which takes a compound biological enzyme preparation as a main effective active matter and contains (A) a biological enzyme compound; (B) a gellan gum slow-release gel system; (C) a surfactant system accounting for 4.0-10wt% of the composition; and (D) the balance of water-containing carrier suitable for general cosmetics. The shelf life of the gel for shaving whiskers and cleaning the face is more than two years, and the effects of efficiently controlling grease and removing bacteria, softening whiskers and enhancing cleaning are realized through the action of biological enzymes.

Description

A kind of slow-release bio ferment shaves face cleaning gel combination
Technical field
The invention belongs to household chemicals field, particularly to a kind of biologic enzyme carried with gellan gum bag for control oil effect active matter The face cleaning that shaves compositions.
Background technology
Ferment washes one of most important biological innovative technology of industry as liquid, latent in terms of economy and environment sustainable development Power is huge, it has also become promote an important force of prospect of Chinese washing products industry sustainable development.Using ferment as the liquid of auxiliary agent Compared with washing product and tradition liquid washing product, dirt-removing power is higher, and range of application is wider.Owing to ferment has the specificity of height, General only to a certain class material effect, often multiple ferment is mixed making compound additive.It is said that in general, ferment is all only Can could keep activity in suitable pH and temperature range, although the activity of natural ferment is the highest, but be suitable for interval narrow, surely Qualitative difference.
Function ferment compound formulation, on the basis of above present Research, is applied to individual and washes and protect product by the present invention, improves Use effect of product, and solve and washing the stability problem protecting in formula.
Summary of the invention
It is an object of the invention to provide the face cleaning compositions that shaves that effectively control oil is antibacterial, the present invention is real by the following method Existing:
A kind of control degerming face cleaning gel combination that shaves of oil, with compound bio enzyme preparation for primary efficacy active matter, bag Contain:
(A) compound bio enzyme preparation:
I () accounts for the lipase of composition weight 0.01% to 0.2%;
(ii) bromelain of composition weight 0.01% to 0.3% is accounted for;
(iii) the polyhydric alcohol stabilization additives of composition weight 3.0% to 10.0% is accounted for;
() accounts for the lactic acid stabilization additives of composition weight 0.5% to 1.5%.
(B) gellan gum sustained-release gel system:
I () percentage by weight is the gellan gum powder of 0.05%-0.3%;
(ii) calcium chloride of 0.05%-0.15%;
(C) surfactant system of composition weight 4.0%-10% is accounted for:
(i) 3.5-7.0% sodium lauryl sulfate;
(ii) decyl glucoside of 0.5-1.6%;
(iii) 0-1.4% cocamido propyl betaine;
(D) surplus is to be suitable for the aqueous carrier of vague generalization cosmetic.
Described gellan gum powder be high acyl gellan gum and low acyl gellan gum be the most compounding of 1:2 to 2:1 according to weight ratio Thing.
Described polyhydric alcohol is fructose, mannitol, sorbitol, trehalose, 1,2-butanediol, the combination in any of glycerol.
Beneficial effects of the present invention: ferment lipase of the present invention can effectively hydrolyzing oils and fats, there is Controlling oil effect;Egg White enzyme acts on hair protein, softens beard, may also act to the aging cutin layer on human body skin, promote it to degenerate, decompose, Remove, promote skin metabolism, reduce the skin color depth phenomenon caused because of Exposure to Sunlight.
Using biologic enzyme preparation is main control oil active matter, under the conditions of the low table amount of applying flexibly, has efficient effect Effect, and lower relative to chemical reagent zest, and biocompatibility is more preferable.Screened by enzyme stabilization additives and optimize and The dual function of gellan gum parcel isolation, solves biological enzyme formulation and washes system easy in inactivation at liquid, the defect that the shelf-life is too short.
Detailed description of the invention
Compositional selecting and the effect of the present invention will be described in detail below.
In ferment compound formulation of the present invention, lipase is commercial enzyme preparation, and enzyme activity is 8000-10000u/ml;Spinach Trailing plants protease is commercial enzyme preparation, and enzyme activity is 50 000-100000u/ml.Described lipase can effectively hydrolyzing oils and fats, tool There is Controlling oil effect;Protease acts on hair protein, softens beard, may also act to the aging cutin layer on human body skin, promotees Make it degenerate, decompose, remove, promote skin metabolism, reduce the skin color depth phenomenon caused because of Exposure to Sunlight.Described lipase and Bromelain has higher activity in pH6-10, temperature 30-50 DEG C scope,
Gellan gum of the present invention, another name glucopyranosiduronic acid and 6-deoxidation-L-mannopyranose and D-glucopyra The polymer of sugar acetas, is a kind of Linear Polymer polysaccharide.The elementary cell repeated polymerization that is made up of 4 monosaccharide molecule and Becoming. its elementary cell is by 1,3-and 2 glucose residues of Isosorbide-5-Nitrae-connection, 1,31 glucuronic acid residue connected, 1 the rhamnose residue composition connected with Isosorbide-5-Nitrae.Wherein glucuronic acid can by potassium, sodium, calcium, magnesium with become salt-mixture.And Natural gellan gum closes O acyl group (glyceroyl and acetyl group).It is low firmly that natural or title high acyl gellan gum can form high resiliency Degree gel.Described high acyl gellan gum molecular structural formula is:
Described low acyl gellan gum is to generate after acetylation gellan gum processes removing O acyl group by alkali, its molecular structural formula As follows:
Alkyl polyglucoside (Alkyl Polyglycoside) molecular formula in the present invention is (C6O5H6)nOR, wherein fatty alcohol Carbochain R is C8-C16, average degree of polymerization n is 1.3-1.6, preferably 1.5-1.6;Alkyl polyglucoside is with starch or glucose and natural grease Fat alcohol is raw material.Obtaining through chemosynthesis, fatty alcohol is averagely combined with more than one glucose molecule, this statistical flat The average degree of polymerization of the most so-called APG.Described alkyl polyglucoside HLB value changes greatly because the degree of polymerization is different, preferably selects The HLB value alkyl polyglucoside product more than 8.0.Described alkyl polyglucoside can be the Plantacare 2000UP of BASF AG.Described Alkyl polyglucoside bio-toxicity is the least, LD50=10000~15000mg/kg, its production process is without the three wastes, ultimate biodegradation (20 ~30 days) all more than 90%, environmental sound, can be rated as green surface activity.
Using method
The face cleaning gel that shaves of the present invention can be used directly can also be adopted as face cleaning gel or shaving gel in face Use as the spraying of curry type with aerosol type pump head
Preparation embodiment I-Ⅹ V
The present invention shave face cleaning compositions can by any known or other effectively be applicable to provide Gel Compositions Prepared by the technology of thing.Suitably described in preparation embodiment I-Ⅹ V, the method for gel combination is as follows: appropriate amount of deionized water adds To retort, it is heated to 100 DEG C, insulation;By soluble in water for components whole with C, stirring and dissolving is complete;It is down to 30-35 DEG C, adds Enter each component of A, D;It is eventually adding B (ii) component.
Embodiment I-V
Embodiment VI-Ⅹ
Embodiment Ⅺ-Ⅹ V
Shelf life of products is analyzed
The mensuration of described shelf life of products, using this test of accelerated test is to carry out under acceleration conditions.Test sample is wanted Ask three batches, by commercially available back, place 6 months under conditions of temperature 40 DEG C ± 2 DEG C, relative humidity 75% ± 5%.Device therefor Temperature ± 2 DEG C, relative humidity ± 5% should be able to be controlled, and true temperature can be monitored with humidity.Testing period the 1st Month, 2 months, 3 months, 6 the end of month separately sampled once, high spot reviews project includes lipase and the survey of protease retentive activity Fixed.Lipase measurement method is with reference to National Standard of the People's Republic of China's GB/T 23535-2009 normal potential titrimetry;Albumen Activity determination method employing-National Standard of the People's Republic of China's GB/T 23527--2009 protease preparation standard forint phenol Method.Result shows embodiment I-Ⅹ V 6 months accelerated tests of lipase used by the present invention, and retentive activity is more than 60%;Albumen Enzyme retentive activity is more than 80%.
Efficacy assessments
The sensory evaluation method of described efficacy assessments is: 15 embodiments and the commercially available face cleaning gel X1 that shaves are issued 30 surveys Examination personnel try out.Using effect (is softened beard and skin by tested personnel according to foam volume, control oil effect and comfort Irritating aggregative indicator) effect marks.Standards of grading use 7 points of systems, 0 point entirely without effect, 1-2 to no effect, 3-4 branch Dividing effective, 5-6 divides effective, and 6-7 divides effect notable.

Claims (3)

1. the face cleaning that a shaves gel combination, with compound bio enzyme preparation for primary efficacy active matter, comprises:
(A) compound bio enzyme activity thing, this active matter component is:
I () accounts for the lipase of composition weight 0.01% to 0.2%;
(ii) bromelain of composition weight 0.01% to 0.3% is accounted for;
(iii) the polyhydric alcohol stabilization additives of composition weight 3.0% to 10.0% is accounted for;
() accounts for the lactic acid stabilization additives of composition weight 0.5% to 1.5%;
(B) gellan gum sustained-release gel system, this system component is:
I () percentage by weight is the gellan gum powder of 0.05%-0.3%;
(ii) calcium chloride of 0.05%-0.15%;
(C) accounting for the surfactant system of composition weight 4.0%-10%, this system component is:
(i) 3.5-7.0% sodium lauryl sulfate;
(ii) decyl glucoside of 0.5-1.6%;
(iii) 0-1.4% cocamido propyl betaine;
(D) surplus is to be suitable for the aqueous carrier of vague generalization cosmetic.
Compositions the most according to claim 1, it is characterised in that described gellan gum is high acyl gellan gum and low acyl gellan gum According to any compound that weight ratio is 1:2 to 2:1.
Compositions the most according to claim 1, it is characterised in that described polyhydric alcohol is fructose, mannitol, sorbitol, Sargassum Sugar, 1,2-butanediol, the combination in any of glycerol.
CN201610881257.1A 2016-10-08 2016-10-08 Slow-release biological enzyme gel composition for shaving whiskers and cleaning face Pending CN106309155A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610881257.1A CN106309155A (en) 2016-10-08 2016-10-08 Slow-release biological enzyme gel composition for shaving whiskers and cleaning face

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Application Number Priority Date Filing Date Title
CN201610881257.1A CN106309155A (en) 2016-10-08 2016-10-08 Slow-release biological enzyme gel composition for shaving whiskers and cleaning face

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101668851A (en) * 2004-08-19 2010-03-10 隆萨股份公司 Aqueous enzyme delivery system
CN101945988A (en) * 2008-02-15 2011-01-12 宝洁公司 Cleaning compositions
CN105168092A (en) * 2015-10-10 2015-12-23 严芳 Face cleaning composition with moisture-preserving function and skin whitening function and preparing method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101668851A (en) * 2004-08-19 2010-03-10 隆萨股份公司 Aqueous enzyme delivery system
CN101945988A (en) * 2008-02-15 2011-01-12 宝洁公司 Cleaning compositions
CN105168092A (en) * 2015-10-10 2015-12-23 严芳 Face cleaning composition with moisture-preserving function and skin whitening function and preparing method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
裘炳毅: "《现代化妆品科学与技术 下册》", 31 March 2016, 中国轻工业出版社 *

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Application publication date: 20170111