CN106266846A - 一种用于治疗月经不调的汤剂药物及其制备方法 - Google Patents

一种用于治疗月经不调的汤剂药物及其制备方法 Download PDF

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CN106266846A
CN106266846A CN201610897707.6A CN201610897707A CN106266846A CN 106266846 A CN106266846 A CN 106266846A CN 201610897707 A CN201610897707 A CN 201610897707A CN 106266846 A CN106266846 A CN 106266846A
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罗兴贵
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Chengdu Xing More Biotechnology LLC
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Abstract

本发明属于中药制剂领域，目的是根据中医对月经不调的认识机理而提供的一种用于治疗月经不调的汤剂药物，所述药物的各个组分及其质量份比如下：柴胡3～12g、益母草3～8g、白术8～16g、制何首乌6～12g、石见穿6～16g、桃仁8～16g、红花3～12g、肉苁蓉10～16g、香附5～12g、牛膝15～26g、川芎3～10g、巴戟天6～16g、知母6～15g、川断6～16g、山药15～32g、三棱5～12g、当归8～16g、甘草3～12g、虎杖10～16g、菟丝子15～26g；本发明提供的药物是一个标本兼治的中药组方。

Description

一种用于治疗月经不调的汤剂药物及其制备方法
技术领域
本发明属于中药制剂领域，具体涉及一种用于治疗月经不调的汤剂药物，特别是供月经不调患者使用的汤剂药物及其制备方法的领域。
背景技术
中医认为，月经失调也称月经不调，是妇科常见病。表现为月经周期提前推后或出血量异常，或是月经前、经期时的腹痛及全身症状。病因可能是器质性病变或是功能失常。许多全身性疾病如血液病(血小板无力症)、高血压、内分泌失调、流产、宫外孕、葡萄胎、高催乳素血症、肿瘤(如卵巢肿瘤、子宫肌瘤)、乳腺腺病、结核病(输卵管结核、子宫内膜结核)、炎症(慢性子宫内膜炎、慢性输卵管卵巢炎)等均可引起月经不调。
月经能否正常来潮，与肝、脾、肾以及冲任二脉关系最大。而导致月经不调的原因，主要以内分泌失调与血热、气虚等因素关系最为密切。本病的病因主要是气血则统摄无权，冲任不固；血热则热扰冲任，伤及胞宫，血海不宁，均可使月经先期而至。其症状表现：月经来潮周期总是提前七天以上，甚至一个月内两次来潮，或伴有心胸烦燥，舌红苔黄，小腹空坠，手足心发热等症状。
那么，就如何找到一种可有效治疗月经不调的药物，是我们目前急需要解决的问题。
发明内容
随着我国中医中药学的不断发展，在治疗月经不调上，人们逐渐意识到了中医治疗月经不调的优点，且在治疗过程中疗效好、见效快、毒副作用小等优势，针对现有西医治疗月经不调的现状，本发明的目的是在于提供一种用于治疗月经不调的汤剂药物，以解决月经不调患者早日恢复健康的问题。该药物是以常见的中药为原料，通过选择合理的药物及质量份比，可有效治疗上述月经不调。
为达到上述发明的目的，本发明所采用的技术方案为：提供一种用于治疗月经不调的汤剂药物及其制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
柴胡3～12g、益母草3～8g、白术8～16g、制何首乌6～12g、石见穿6～16g、桃仁8～16g、红花3～12g、肉苁蓉10～16g、香附5～12g、牛膝15～26g、川芎3～10g、巴戟天6～16g、知母6～15g、川断6～16g、山药15～32g、三棱5～12g、当归8～16g、甘草3～12g、虎杖10～16g、菟丝子15～26g。
一种用于治疗月经不调的汤剂药物及其制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
柴胡5～11g、益母草5～7g、白术10～14g、制何首乌8～11g、石见穿8～14g、桃仁10～14g、红花6～11g、肉苁蓉11～14g、香附8～11g、牛膝18～23g、川芎5～9g、巴戟天10～14g、知母8～13g、川断8～14g、山药18～28g、三棱8～11g、当归10～14g、甘草6～11g、虎杖11～14g、菟丝子18～23g。
一种用于治疗月经不调的汤剂药物及其制备方法，其特征在于，所述“最佳方案”的药物的各个组分及其质量份比如下所示：
柴胡10g、益母草6g、白术12g、制何首乌10g、石见穿12g、桃仁12g、红花10g、肉苁蓉12g、香附10g、牛膝20g、川芎8g、巴戟天12g、知母12g、川断12g、山药25g、三棱10g、当归12g、甘草10g、虎杖12g、菟丝子20g。
一种用于治疗月经不调的汤剂药物及其制备方法，其特征在于，所述方法包括如下步骤制备而成：
A、将上述原料中药拣去杂质和粉尘后，按照质量份比分别粉碎成粗粒状包煎；
B、将包好的原料中药放入冷开水中浸泡半个小时，然后再将浸泡好的药物和浸泡药物的澄清液一并放入砂锅内，注入过药36mm的冷开水进行第一次煎煮50分钟，滤取药液后，再次注入过药32mm的微温开水进行第二次煎煮38分钟，二次混合浓缩成50%的中药液400毫升备用。
一种用于治疗月经不调的汤剂药物及其制备方法，其特征在于，所述服用方法为：将制备好的中药液以一天服用，每日一剂，早晚分服，给药量200毫升/次。10天为一个疗程，服药3～6个疗程后，症状消失，病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料，充分发挥各组分的药理功效：
柴胡，性味：味苦、辛、性微寒，具有解表退热、疏肝解郁、升举阳气之功效，用于治疗外感发热、寒热往来、疟疾、肝郁胁痛乳胀、头痛头眩、月经不调、气虚下陷之脱肛、子宫脱垂、胃下垂等症；
益母草，性味：辛苦、凉，具有活血、祛瘀、调经、消水之功效，用于治疗月经不调、胎漏难产、胞衣不下、产后血晕、瘀血腹痛、崩中漏下、尿血、泻血、痈肿疮疡；
白术，性味：味苦、甘、性温，具有健脾益气、燥湿利水、止汗、安胎之功效，用于治疗脾气虚弱、神疲乏力、食少少腹胀、大便溏薄、水饮内停、小便不利、水肿、痰饮眩晕、温痹酸痛、气虚自汗、胎动不安；
制何首乌，性味：苦、甘、涩、温，具有补肝肾、益精血、乌须发、强筋骨之功效，用于治疗血虚萎黄、眩晕耳鸣、须发早白、腰膝酸软、肢体麻木、崩漏带下、久疟体虚、高血脂；
石见穿，性味：味辛、苦、性微寒，具有活血化瘀、清热利湿、散结消肿之功效，用于治疗月经不调、痛经、经闭、崩漏、便血、湿热黄疸、热热毒血痢、淋痛、带下、风湿骨痛、瘰疬、疮肿、乳痈、带状疱疹、麻风、跌打伤肿；
桃仁，性味：苦甘、平，无毒，具有破血行瘀、润燥滑肠之功效，用于治疗经闭、癥瘕、热病蓄血、风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘；
红花，性味：味辛、性温，具有活血能经、祛瘀止痛之功效，用于治疗经闭、痛经、产后瘀阻腹痛、胞痹心痛症瘕积聚、跌打损伤、关节疼痛、中风偏竣、斑疹等症；
肉苁蓉，性味：味甘、咸、性温，具有补肾阳、益精血、润肠道之功效，用于治疗肾阳虚衰、精血不足之阳痿、遗精、白浊、尿频余沥、腰痛脚弱、耳鸣目花、月经衍期、宫寒不孕、肠燥便秘；
香附，性味：味辛、微寒，无毒，具有理气解郁、调经止痛、安胎之功效，用于治疗胁肋胀痛、乳房胀育、疝气疼痛、月经不调、脘腹痞满疼痛、嗳气吞酸、呕恶、经行腹痛、崩漏带下、胎动不安等病症；
牛膝，性味：苦、酸、性平，具有补肝肾、强筋骨、活血通经、引敌国（火）下行、利尿通淋之功效，用于治疗腰膝酸痛、下肢痿软、血滞经闭、痛经、产后血瘀腹痛、征瘕、胞衣不下、热淋、血淋、跌打损伤、痈肿恶疮、咽喉肿痛；
川芎，性味：辛、温，具有活血行气、祛风止痛之功效，用于治疗安抚神经、正头风头痛、症瘕腹痛、胸胁刺痛、跌扑肿痛、头痛、风湿痹痛；
巴戟天，性味：辛甘、温，具有补肾助阳、强筋壮骨、祛风除湿之功效，用于治疗肾虚阳痿、遗精早泄、少腹冷痛、小便不禁、宫冷不孕、风寒湿痹、腰膝酸软、风湿肢气；
知母，性味：味苦、性寒，具有清热泻火、滋阴润燥、止渴除烦之功效，用于治疗温热病、高热烦渴、咳嗽气喘、燥咳、便秘、骨蒸潮热、虚烦不眠、消渴淋浊；
川断，性味：味苦、辛、性微温，具有补肝肾、强筋骨、调血脉、止崩漏之功效，用于治疗腰背酸痛、肢节痿痹、跌扑创伤、损筋折骨、胎动漏红、血崩、遗精、带下、痈疽疮肿；
山药，性味：甘、平，具有补脾、养肺、固肾、益精之功效，用于治疗脾虚泄泻、食少浮肿、肺虚咳喘、消渴、遗精、带下、肾虚尿频，外用治痈肿、瘰疬等症；
三棱，性味：味辛、涩、凉，具有破血行气、消积止痛之功效，用于治疗症瘕痞块、瘀滞经闭、痛经、食积胀痛、跌年伤痛；
当归，性味：性温、味甘辛, 具有补血和血、调经止痛、润燥滑肠之功效，用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的月经不调、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤；
甘草，性味：甘、平，具有益气补中、缓急止痛、润肺止咳、泻火解毒、调和诸药之功效，用于治疗倦怠食少、肌瘦面黄、心悸气短、腹痛便溏、四肢挛急疼痛、脏躁、咳嗽气喘、咽喉肿痛、痈疮肿痛、小儿胎毒及药物、食物中毒；
虎杖，性味：苦、酸、性微寒，具有活血散瘀、祛风通络、清热利湿、解毒之功效，用于治疗妇女经闭、痛经、产后恶露不下、癥瘕积聚、跌扑损伤、风湿痹痛、湿热黄疸、淋浊带下、疮疡肿毒、毒蛇咬伤、水火烫伤；
菟丝子，性味：辛甘、平，具有补肾益精、养肝明目、固胎止泄之功效，用于治疗腰膝酸痛、遗精、阳痿、早泄、不育、消渴、淋浊、遗尿、目昏耳鸣、胎动不安、流产、泄泻等症。
本发明药物是基于中医治疗月经不调的原则，从药理作用及其作用机制认为：就月经不调，本发明所提供的药物中的各原料中药药效共奏，对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述月经不调的治疗而提出的一种中药配方，采用该配方制备的药物药效好，见效快，是一个标本兼治的中药组方，特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述：
实施例1：
一种用于治疗月经不调的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
柴胡10g、益母草6g、白术12g、制何首乌10g、石见穿12g、桃仁12g、红花10g、肉苁蓉12g、香附10g、牛膝20g、川芎8g、巴戟天12g、知母12g、川断12g、山药25g、三棱10g、当归12g、甘草10g、虎杖12g、菟丝子20g。
实施例2：
一种用于治疗月经不调的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
柴胡11g、益母草7g、白术14g、制何首乌11g、石见穿14g、桃仁14g、红花11g、肉苁蓉14g、香附11g、牛膝23g、川芎9g、巴戟天14g、知母13g、川断14g、山药28g、三棱11g、当归14g、甘草11g、虎杖14g、菟丝子23g。
实施例3：
一种用于治疗月经不调的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
柴胡12g、益母草8g、白术16g、制何首乌12g、石见穿16g、桃仁16g、红花12g、肉苁蓉16g、香附12g、牛膝26g、川芎10g、巴戟天16g、知母15g、川断16g、山药32g、三棱12g、当归16g、甘草12g、虎杖16g、菟丝子26g。
典型病例
经临床诊断治疗月经不调患者共585例，年龄为18岁以上的295例，只有290例为18岁以下。585例患者中痊愈的570例，显效的的15例，总有效率达100%。

Claims (3)

1.一种用于治疗月经不调的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
柴胡3～12g、益母草3～8g、白术8～16g、制何首乌6～12g、石见穿6～16g、桃仁8～16g、红花3～12g、肉苁蓉10～16g、香附5～12g、牛膝15～26g、川芎3～10g、巴戟天6～16g、知母6～15g、川断6～16g、山药15～32g、三棱5～12g、当归8～16g、甘草3～12g、虎杖10～16g、菟丝子15～26g。
2.根据权利要求1所述的用于治疗月经不调的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
柴胡5～11g、益母草5～7g、白术10～14g、制何首乌8～11g、石见穿8～14g、桃仁10～14g、红花6～11g、肉苁蓉11～14g、香附8～11g、牛膝18～23g、川芎5～9g、巴戟天10～14g、知母8～13g、川断8～14g、山药18～28g、三棱8～11g、当归10～14g、甘草6～11g、虎杖11～14g、菟丝子18～23g。
3.根据权利要求1至2所述的用于治疗月经不调的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
柴胡10g、益母草6g、白术12g、制何首乌10g、石见穿12g、桃仁12g、红花10g、肉苁蓉12g、香附10g、牛膝20g、川芎8g、巴戟天12g、知母12g、川断12g、山药25g、三棱10g、当归12g、甘草10g、虎杖12g、菟丝子20g。
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* Cited by examiner, † Cited by third party
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