CN106266636A - 一种治疗关节疼痛的新型中药组合物及制备方法 - Google Patents

一种治疗关节疼痛的新型中药组合物及制备方法 Download PDF

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CN106266636A
CN106266636A CN201610868586.2A CN201610868586A CN106266636A CN 106266636 A CN106266636 A CN 106266636A CN 201610868586 A CN201610868586 A CN 201610868586A CN 106266636 A CN106266636 A CN 106266636A
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radix
herba
arthralgia
ramulus cinnamomi
rhizoma
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孙思远
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Sichuan Yichuang Biotechnology Co Ltd
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Abstract

本发明属于中药制剂领域,目的是根据中医对神经性疼痛的认识机理而提供的一种治疗关节疼痛的新型中药组合物,所述中药组合物的各个组分及其质量份比如下:麻黄、桂枝、川芎、丹参、青风藤、当归、防风、熟地黄、地龙、何首乌、桂枝、白芍、枸杞子、白芷、墨旱莲、穿山甲、龟板、白鲜皮、鳖甲、肉苁蓉、补骨脂、韭子、杜仲、续断、天麻、钩藤、白僵蚕、全蝎、石菖蒲、红花、桃仁、鸡血藤、甘草,淀粉适量;本发明提供的药物是一个标本兼治的中药组方。

Description

一种治疗关节疼痛的新型中药组合物及制备方法
技术领域
[0001]本发明属于中药制剂领域,具体涉及一种治疗关节疼痛的新型中药组合物,特别是供关节疼痛患者使用的新型中药组合物及制备方法的领域。
背景技术
[0002]医者认为:关节疼痛主要是由于关节炎或关节病引起。关节疼痛牵涉范围非常广泛,并且种类繁多,因此关节疼痛的鉴别诊断至关重要。关节痛在中医病症中属于肢节痛、肢节肿痛、痹证、痛风等病症范畴。另关节疼痛见《灵枢.百病始生》六经不通四肢,则肢节痛,腰脊乃强”。
[0003]现代医学针对临床某一症状的治疗,往往达不到预期的效果,找不到合适的治疗方法,为了克服上述缺陷,本发明基于中医治疗关节痛的辨病与辨证相结合的原则,标本兼治,虚实并治,内外通调,缓急兼收,筛选出祛风除湿、活血通络、消肿止痛的天然植物药,根据中医理论组方,按照一定的重量配比制备而成。提供一种疗效显著、成本低廉、毒副作用极小,并可有效治疗关节疼痛的中药组合物。
发明内容
[0004]随着我国中医中药学的不断发展,在治疗关节疼痛上,人们逐渐意识到了中医治疗关节疼痛的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗关节疼痛的现状,本发明的目的是在于提供一种治疗关节疼痛的新型中药组合物,以解决关节疼痛患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及其质量份比,可有效治疗上述关节疼痛。
[0005]为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗关节疼痛的新型中药组合物及制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄25〜100g、桂枝25〜100g、川芎50〜100g、丹参50〜160g、青风藤30〜60g、当归80〜160g、防风80〜160g、熟地黄120〜380g、地龙50〜120g、何首乌150〜260g、桂枝20〜80g、白芍100〜200g、枸杞子100〜250g、白芷30〜120g、墨旱莲90〜320g、穿山甲30〜100g、龟板90〜250g、白鲜皮50〜120g、鳖甲100〜300g、肉苁蓉100〜150g、补骨脂80〜160g、韭子60〜120g、杜仲60〜160g、续断100〜250g、天麻80〜160g、钩藤60〜320g、白僵蚕30〜120g、全蝎20〜50g、石菖蒲50〜120g、红花50〜120g、桃仁80〜160g、鸡血藤150〜250g、甘草30〜120g,淀粉适量。
[0006] —种治疗关节疼痛的新型中药组合物及制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄30〜90g、桂枝30〜90g、川考60〜90g、丹参60〜140g、青风藤40〜50g、当归90〜140g、防风90〜140g、熟地黄140〜250g、地龙60〜105g、何首乌170〜230g、桂枝30〜70g、白芍115〜170g、枸杞子115〜220g、白芷40〜105g、墨旱莲100〜280g、穿山甲40〜90g、龟板100〜220g、白鲜皮60〜105g、鳖甲115〜260g、肉苁蓉115〜130g、补骨脂90〜140g、韭子70〜105g、杜仲70〜140g、续断115〜220g、天麻90〜140g、钩藤70〜280g、白僵蚕40〜105g、全蝎26〜45g、石菖蒲60〜105g、红花60〜105g、桃仁90〜140g、鸡血藤170〜220g、甘草40〜105g,淀粉适量。
[0007] —种治疗关节疼痛的新型中药组合物及制备方法,其特征在于,所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示:
麻黄80g、桂枝80g、川;80g、丹参120g、青风藤45g、当归120g、防风120g、熟地黄220g、地龙90g、何首乌200g、桂枝60g、白芍150g、枸杞子200g、白芷90g、墨旱莲250g、穿山甲80g、龟板200g、白鲜皮90g、鳖甲230g、肉苁蓉115g、补骨脂120g、韭子90g、杜仲120g、续断200g、天麻120g、钩藤250g、白僵蚕90g、全蝎40g、石菖蒲90g、红花90g、桃仁120g、鸡血藤200g、甘草90g,淀粉适量。
[0008] —种治疗关节疼痛的新型中药组合物及制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、除淀粉外,将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统制备中药水丸剂的方法,将研磨好的极细末药物和淀粉过筛后,放入药器中混合拌均,然后制备成水丸剂(其水丸的粒度为:4.7mm〜4.8mm),进而晒干,分装密封即可。
[0009] —种治疗关节疼痛的新型中药组合物及制备方法,其特征在于,所述服用方法为:将制备好的水丸剂药物以每日三次服用,早中晚各服一次,给药量5g/次,温水送服。30天为一个疗程,经治疗2〜5个疗程后,症状逐渐减轻或疫愈。
[0010]本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
麻黄,性味:辛苦、温,具有发汗、平喘、利水之功效,用于治疗伤寒表实、发热恶寒无汗、头痛鼻塞、骨节疼痛、咳嗽气喘、风水浮肿、小便不利、风邪顽痹、皮肤不仁、风疹瘙痒;
桂枝,性味:辛、甘、性温,具有散寒解表、温通经脉、通阳化气之功效,用于治疗风寒表证、寒湿痹痛、四肢厥冷、经闭痛经、症瘕结块、胸痹、心悸、痰饮、小便不利;
川芎,性味:辛、温,具有行气开郁、法风燥湿、活血止痛之功效,用于治疗风冷头痛旋晕、胁痛腹疼、寒痹筋挛、经闭、难产、产后瘀阻块痛、痈疽疮疡、月经不调、瘕腹痛、胸胁刺痛、跌扑肿痛、风湿痹痛;
丹参,性味:苦、微寒,具有活血调经、祛瘀止痛、凉血消痈、清心除烦、养血安神之功效,用于治疗月经不调、经闭痛经、症瘕积聚、胸腹刺痛、热痹疼痛、疮疡肿痛、心烦不眠、肝脾肿大、心绞痛等症;
青风藤,性味:味甘、辛性温,小毒,具有祛风除湿、活血消痈之功效,用于治疗跌打损伤、风湿痹痛、闭经、乳痈、骨折;
当归,性味:性温、味甘辛,具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的月经不调、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤;
防风,性味:辛甘、温,具有发表、祛风、胜湿、止痛之功效,用于治疗外感风寒、头痛、目眩、项强、风寒湿痹、骨节酸痛、四肢挛急、破伤风;
熟地黄,性味:甘、微温,具有滋阴补血、益精填髓之功效,用于治疗肝肾阴虚、腰膝酸软、骨蒸潮热、盗汗遗精、内热消渴、血虚萎黄、心悸怔忡、月经不调、崩漏下血、眩晕、耳鸣、须发早白等病症;
地龙,性味:微、咸,具有清势止痉、平肝熄风、通经活络、平喘利尿之功效,用于治疗热病发热狂燥;惊痫抽搐、肝阳头痛、中风偏瘫、风湿痹痛、肺热喘咳、小便不通;
何首乌,性味:苦甘涩、微温,具有补肝、益肾、养血、祛风之功效,用于治疗肝肾阴亏、发须早白、血虚头晕、腰膝软弱、筋骨酸痛、遗精、崩带、久疟、久痢、慢性肝炎、痈肿、瘰疬、肠风、痔疾等症;
桂枝,性味:辛、甘、性温,具有散寒解表、温通经脉、通阳化气之功效,用于治疗风寒表证、寒湿痹痛、四肢厥冷、经闭痛经、症瘕结块、胸痹、心悸、痰饮、小便不利;
白芍,性味:苦、酸、微寒,具有养血和营、缓急止痛、敛阴平肝之功效,用于治疗月经不调、经行腹痛、崩漏、自汗、盗汗、胁肋脘腹疼痛、四肢挛痛、头痛、眩晕等症;
枸杞子,性味:味甘、性平,具有养肝、滋肾、润肺之功效,用于治疗肝肾亏虚、头晕目眩、目视一清、腰膝酸软、阳痿贵精、虚劳咳嗽、消渴引饮;
白芷,性味:味辛、性温,具有祛风除湿、通窃止痛、消肿排脓之功效,用于治疗感冒头痛、眉棱骨痛、牙痛、鼻塞、鼻渊、湿胜久泻、妇女白带、痈疽疮疡、毒蛇咬伤;
墨旱莲,性味:味甘、酸、性凉,具有补益肝肾、凉血止血之功效,用于治疗肝肾不足、头晕目眩、须发早白、吐血、咯血、衄血、便血、血痢、崩、漏、外伤出血;
穿山甲,性味:味咸、性微寒,具有活血散结、通经下乳、消痈溃坚之功效,用于治疗血瘀经闭、症瘕、风湿痹痛、乳汁不下、痈肿、瘰疬;
龟板,性味:咸、甘、微寒,具有滋阴潜阳、益肾强骨、养血补心之功效,用于治疗阴虚潮热、骨蒸盗汗、头晕目眩、虚风内动、筋骨痿软、心虚健忘;
白鲜皮,性味:性寒、味苦,具有清热燥湿、祛风解毒、杀虫之功效,用于治疗湿热疮毒、黄水淋漓、湿疹、疥癣疮癞、风湿热痹、黄疸尿赤;
鳖甲,性味:味咸、性微寒,具有滋阴清热、潜阳熄风、软坚散结之功效,用于治疗阴虚发热、劳热骨蒸、热病伤阴、虚风内动、小作惊痫、久疟、疟母、癥瘕、经闭;
肉苁蓉,性味:味甘、咸、性温,具有补肾阳、益精血、润肠道之功效,用于治疗肾阳虚衰、精血不足之阳痿、遗精、白浊、尿频余沥、腰痛脚弱、耳鸣目花、月经衍期、宫寒不孕、肠燥便秘;
补骨脂,性味:味辛、苦、性温,具有补肾助阳、纳气平喘、温脾止泻之功效,用于治疗肾阳不足、下元虚冷、腰膝冷痛、阳痿精、尿频;遗尿、肾不纳气、虚喘不止、脾肾两虚、大便久泻、白癜风、斑秃、银肩病;
韭子,性味:味辛、甘、性温,具有补益肝肾、壮阳固精之功效,用于治疗肾虚阳痿、腰膝酸软、遗精、尿频、尿浊、带下清稀等病症;
杜仲,性味:甘、微辛、性温,具有补肝肾、强筋骨、安胎之功效,用于治疗腰脊酸疼、阳痿、尿频、小便余沥、风湿痹痛、胎动不安、习惯性流产;
续断,性味:苦辛、微温,具有补肝肾、续筋骨、调血脉之功效,用于治疗腰背酸痛、足膝无力、胎漏、崩漏、带下、遗精、跌打损伤、金疮、痔漏、痈疽疮肿; 天麻,性味:甘、平,具有息风,定惊之功效,用于治疗眩晕眼黑、头风头痛、肢体麻木、半身不遂、语言蹇涩、小儿惊痫动风等症;
钩藤,性味:甘苦、微寒,具有清热平肝、熄风止痉之功效,用于治疗小儿惊风、夜啼、热盛动风、子痫、肝阳眩晕、肝火头胀痛等病症;
白僵蚕,性味:味辛、咸、性平,具有祛风止痉、化痰散结、解毒利咽之功效,用于治疗惊痫抽搐、中风口歪眼斜、偏正头痛、咽喉肿痛、瘰疬、痄腮、风疹、疮毒等症;
全蝎,性味:咸辛、平,有毒,具有祛风、止痉、通络、解毒之功效,用于治疗惊风抽摘、癫痫、中风、半身不遂、口眼歪斜、偏头痛、风湿痹痛、破伤风、淋巴结结核、风疹疮肿;
石菖蒲,性味:辛、微温,具有开窍、豁痰、理气、活血、散风、去湿之功效,用于治疗癫痫、痰厥、,热病神昏、健忘、气闭耳聋、心胸烦闷、胃痛、腹痛、风寒湿痹、痈疽肿毒、跌打损伤;红花,性味:味辛、性温,具有活血能经、祛瘀止痛之功效,用于治疗经闭、痛经、产后瘀阻腹痛、胞痹心痛症瘕积聚、跌打损伤、关节疼痛、中风偏竣、斑疹;
桃仁,性味:苦甘、平,具有破血行瘀、润燥滑肠之功效,用于治疗经闭、症瘕、热病蓄血、风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘等症;
鸡血藤,性味:味苦、微甘、性温,具有活血舒筋、养血调经之功效,用于治疗手足麻木、肢体瘫痪、风湿痹痛、妇女有经不调、痛经、闭经等症;
甘草,性味:甘、平,具有和中缓急、润肺、解毒、调和诸药之功效,用于治疗脾胃虚弱、食少、腹痛便溏、劳倦发热、肺痿咳嗽、心悸、惊痫,生用:治咽喉肿痛、消化性溃疡、痈疽疮疡、解药毒及食物中毒。
[0011]本发明药物是基于中医治疗关节疼痛的原则,从药理作用及作用机制认为:就关节疼痛,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
[0012]本发明就是针对上述关节疼痛的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗关节疼痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄80g、桂枝80g、川;80g、丹参120g、青风藤45g、当归120g、防风120g、熟地黄220g、地龙90g、何首乌200g、桂枝60g、白芍150g、枸杞子200g、白芷90g、墨旱莲250g、穿山甲80g、龟板200g、白鲜皮90g、鳖甲230g、肉苁蓉115g、补骨脂120g、韭子90g、杜仲120g、续断200g、天麻120g、钩藤250g、白僵蚕90g、全蝎40g、石菖蒲90g、红花90g、桃仁120g、鸡血藤200g、甘草90g,淀粉适量。
[0013] 实施例2:
一种治疗关节疼痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄90g、桂枝90g、川芎90g、丹参140g、青风藤50g、当归140g、防风140g、熟地黄250g、地龙105g、何首乌230g、桂枝70g、白芍170g、枸杞子220g、白芷105g、墨旱莲280g、穿山甲90g、龟板220g、白鲜皮105g、鳖甲260g、肉苁蓉130g、补骨脂140g、韭子105g、杜仲140g、续断220g、天麻140g、钩藤280g、白僵蚕105g、全蝎45g、石菖蒲105g、红花105g、桃仁140g、鸡血藤220g、甘草105g,淀粉适量。
[0014] 实施例3:
一种治疗关节疼痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
麻黄100g、桂枝100g、川;100g、丹参160g、青风藤60g、当归160g、防风160g、熟地黄380g、地龙120g、何首乌260g、桂枝80g、白芍200g、枸杞子250g、白芷120g、墨旱莲320g、穿山甲100g、龟板250g、白鲜皮120g、鳖甲300g、肉苁蓉150g、补骨脂160g、韭子120g、杜仲160g、续断250g、天麻160g、钩藤320g、白僵蚕120g、全蝎50g、石菖蒲120g、红花120g、桃仁160g、鸡血藤250g、甘草120g,淀粉适量。
[0015] 典型病例
经临床诊断治疗关节疼痛患者共665例,年龄为52岁以上的365例,只有300例为52岁以下。665例患者中痊愈的590例,显效的的22例,无效53例,总有效率达92%。结果表明,本发明的药物对治疗关节疼痛有极其显著的疗效。

Claims (3)

1.一种治疗关节疼痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示: 麻黄25〜100g、桂枝25〜100g、川芎50〜100g、丹参50〜160g、青风藤30〜60g、当归80〜160g、防风80〜160g、熟地黄120〜380g、地龙50〜120g、何首乌150〜260g、桂枝20〜80g、白芍100〜200g、枸杞子100〜250g、白芷30〜120g、墨旱莲90〜320g、穿山甲30〜100g、龟板90〜250g、白鲜皮50〜120g、鳖甲100〜300g、肉苁蓉100〜150g、补骨脂80〜160g、韭子60〜120g、杜仲60〜160g、续断100〜250g、天麻80〜160g、钩藤60〜320g、白僵蚕30〜120g、全蝎20〜50g、石菖蒲50〜120g、红花50〜120g、桃仁80〜160g、鸡血藤150〜250g、甘草30〜120g,淀粉适量。
2.根据权利要求1所述的治疗关节疼痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示: 麻黄30〜90g、桂枝30〜90g、川考60〜90g、丹参60〜140g、青风藤40〜50g、当归90〜140g、防风90〜140g、熟地黄140〜250g、地龙60〜105g、何首乌170〜230g、桂枝30〜70g、白芍115〜170g、枸杞子115〜220g、白芷40〜105g、墨旱莲100〜280g、穿山甲40〜90g、龟板100〜220g、白鲜皮60〜105g、鳖甲115〜260g、肉苁蓉115〜130g、补骨脂90〜140g、韭子70〜105g、杜仲70〜140g、续断115〜220g、天麻90〜140g、钩藤70〜280g、白僵蚕40〜105g、全蝎26〜45g、石菖蒲60〜105g、红花60〜105g、桃仁90〜140g、鸡血藤170〜220g、甘草40〜105g,淀粉适量。
3.根据权利要求1至2所述的治疗关节疼痛的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示: 麻黄80g、桂枝80g、川;80g、丹参120g、青风藤45g、当归120g、防风120g、熟地黄220g、地龙90g、何首乌200g、桂枝60g、白芍150g、枸杞子200g、白芷90g、墨旱莲250g、穿山甲80g、龟板200g、白鲜皮90g、鳖甲230g、肉苁蓉115g、补骨脂120g、韭子90g、杜仲120g、续断200g、天麻120g、钩藤250g、白僵蚕90g、全蝎40g、石菖蒲90g、红花90g、桃仁120g、鸡血藤200g、甘草90g,淀粉适量。
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107184748A (zh) * 2017-06-21 2017-09-22 合肥丰瑞隆生物科技有限公司 一种治疗肾功能不全引起的阴部疼痛的中药组合物
FR3081326A1 (fr) * 2018-05-24 2019-11-29 Xun Huang Composition pharmaceutique utilisee pour un chapeau de traitement medical et de soins de sante

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181568A (zh) * 2007-12-04 2008-05-21 朱惠芬 一种治骨质增生及关节疼痛的中药制剂
WO2016017840A1 (ko) * 2014-07-31 2016-02-04 안국약품 주식회사 천마 추출물을 포함하는 통증 완화 또는 치료제

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181568A (zh) * 2007-12-04 2008-05-21 朱惠芬 一种治骨质增生及关节疼痛的中药制剂
WO2016017840A1 (ko) * 2014-07-31 2016-02-04 안국약품 주식회사 천마 추출물을 포함하는 통증 완화 또는 치료제

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107184748A (zh) * 2017-06-21 2017-09-22 合肥丰瑞隆生物科技有限公司 一种治疗肾功能不全引起的阴部疼痛的中药组合物
FR3081326A1 (fr) * 2018-05-24 2019-11-29 Xun Huang Composition pharmaceutique utilisee pour un chapeau de traitement medical et de soins de sante

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