CN107184748A - 一种治疗肾功能不全引起的阴部疼痛的中药组合物 - Google Patents
一种治疗肾功能不全引起的阴部疼痛的中药组合物 Download PDFInfo
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Abstract
本发明公开一种由于肾功能不全引起的阴部疼痛的中药组合物，属于中药技术领域，是由下述重量份的药材制备而成：海马40～60份，龟板25～35份，鳖甲25～35份，地龙15～25份，全蝎15～25份，白僵蚕15～25份，蝉衣5～15份，黄芪10～20份，当归15～25份，西红花25～35份，芡实10～20份，前胡10～20份，桂枝25～35份，甘草5～15份，麝香3～8份，冰片5～15份，桃仁10～20份。本发明中药组合物，主要是壮阳袪火，兼以补肝肾阴虚，疏通经络，调节微循环，达到止痛目的。
Description
技术领域
本发明涉及中药技术领域，具体涉及一种治疗肾功能不全引起的阴部疼痛的中药组合物。
背景技术
中医认为，肾为人的先天之本，元阴元阳之处所，由于肾功能不全或病变。水火之藏失去其生理机能，阴私处出现疼痛。由于肾功能不全常引起阴囊神经性疼痛、睾丸炎症、前列腺炎等也是造成疼痛的原因。
目前，这类疾病的治疗药物主要抗生素类和中成药等。临床实践证明，单纯使用西药治疗效果不理想，而中医药在我国已经成为治疗该病的主要方法之一。中医药是中华民族的宝贵文化遗产，在治疗常见病、多发病、疑难病症等方面有其特殊的作用。中药因其疗效独特、毒副作用小等优点越来越受到世人的瞩目。目前治疗少腹、腰骶、会阴、睾丸疼痛的中成药较为少见，大多为医院制剂。
发明内容
本发明提出一种治疗肾功能不全引起的阴部疼痛的中药组合物，主要是壮阳袪火，兼以补肝肾阴虚，疏通经络，调节微循环，达到止痛目的。
本发明的技术方案是这样实现的：
一种治疗肾功能不全引起的阴部疼痛的中药组合物，是由下述重量份的药材制备而成：海马40～60份，龟板25～35份，鳖甲25～35份，地龙15～25份，全蝎15～25份，白僵蚕15～25份，蝉衣5～15份，黄芪10～20份，当归15～25份，西红花25～35份，芡实10～20份，前胡10～20份，桂枝25～35份，甘草5～15份，麝香3～8份，冰片5～15份，桃仁10～20份。
其中，优选地，一种治疗肾功能不全引起的阴部疼痛的中药组合物，是由下述重量份的药材制备而成：海马45～55份，龟板28～32份，鳖甲28～32份，地龙18～22份，全蝎18～22份，白僵蚕18～22份，蝉衣8～12份，黄芪12～18份，当归18～22份，西红花28～32份，芡实12～18份，前胡12～18份，桂枝28～32份，甘草8～12份，麝香4～6份，冰片8～12份，桃仁12～18份。
其中，优选地，一种治疗肾功能不全引起的阴部疼痛的中药组合物，是由下述重量份的药材制备而成：海马50份，龟板30份，鳖甲30份，地龙20份，全蝎20份，白僵蚕20份，蝉衣10份，黄芪15份，当归20份，西红花30份，芡实15份，前胡15份，桂枝30份，甘草10份，麝香5份，冰片10份，桃仁15份。
其中，各药材的性味、归经及功效为：
海马：味甘，温，入肾经，具有补肾壮阳，消癓瘕之功效。
龟板：味咸甘，平，入肝、肾经，具有滋阴，潜阳，补肾，健骨之功效。
鳖甲：味咸，性微寒，归肝、肾经，具有滋阴潜阳，退热除蒸，软坚散结之功效。
地龙：性寒，味咸；归肝、胃、肺、膀胱经，具有清热平肝、熄风止痉、平喘、利尿、通络除痹的功效。
全蝎：性辛，平；归肝经；具有息风镇痉，通络止痛，攻毒散结之功效。
白僵蚕：味咸，平；入肝、肺，胃经；具有祛风解痉，化痰散结之功效。
蝉衣：味甘、咸，性凉；归肺、肝经；具有疏散风热，利咽开音，透疹，明目退翳，息风止痉之功效。
黄芪：味甘，微温；归肺、脾、肝、肾经；有益气固表、敛汗固脱、托疮生肌、利水消肿之功效。
当归：味甘、辛、温；归肝、心、脾经；具有补血；活血；调经止痛；润燥滑肠之功效。
西红花：味甘，性平；归心、肝经；具有活血化瘀，凉血解毒，解郁安神之功效。
芡实：味甘、涩，性平；归脾、肾经；具有益肾固精，补脾止泻，除湿止带之功效。
前胡：苦、辛，微寒。入肺经，有疏散风热；降气化痰的功效。
桂枝：性味辛、甘，温，入肺、心、膀胱经，具有补元阳、通血脉、暖脾胃之功效。
甘草：味甘，平；入脾、胃、肺经；具有益气补中；缓急止痛；润肺止咳；泻火解毒；调和诸药。
麝香：味辛；性温。入心、脾、肝经。
冰片：味辛苦，凉。入心、肺经。具有通诸窍，散郁火，去翳明目，消肿止痛。
桃仁：味苦甘，平；入心，肝，大肠，肺，脾经；具有破血行瘀，润燥滑肠之功效。
本发明的有益效果：
本发明处方中地龙和黄芪，蝉衣和前胡配伍打通经脉和络脉，使微循环畅通，通调水道。
白僵蚕和芡实配伍，袪风清热，提高肾小球的微循环功能。
桂枝和甘草，辛甘化阳，振奋心阳，太阳经络散布于心，使心肾相交。
由于肾功能不全，桂枝防止水泛滥，兼有引邪达表。
西红花、桃仁、当归等活血化淤，肾系统微循环更加畅通兼以补阴，补而不腻。
冰片、麝香加强药物的发散效果，冰片能除多余的邪热。
全方针对肾功能不全，肾火衰退，阴阳具衰，以壮阳为主兼以补肝肾之阴，益肉有情之品和本草药同用，以增强药效。本方在治疗由于肾功能不全引起的阴部疼痛具有确切的疗效和良好的开发前景。并且，和治疗这类疾病的抗生素类相比，副作用小。
具体实施方式
下面将结合本发明实施例，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其它实施例，都属于本发明保护的范围。
实施例1
一种治疗肾功能不全引起的阴部疼痛的中药组合物，是由下述重量份的药材制备而成：海马50g，龟板30g，鳖甲30g，地龙20g，全蝎20g，白僵蚕20g，蝉衣10g，黄芪15g，当归20g，西红花30g，芡实15g，前胡15g，桂枝30g，甘草10g，麝香5g，冰片10g，桃仁15g。
实施例2
一种治疗肾功能不全引起的阴部疼痛的中药组合物，是由下述重量份的药材制备而成：海马40g，龟板35g，鳖甲25g，地龙25g，全蝎15g，白僵蚕25g，蝉衣5g，黄芪20g，当归15g，西红花35g，芡实10g，前胡20g，桂枝25g，甘草15g，麝香3g，冰片15g，桃仁10g。
实施例3
一种治疗肾功能不全引起的阴部疼痛的中药组合物，是由下述重量份的药材制备而成：海马60g，龟板25g，鳖甲35g，地龙15g，全蝎25g，白僵蚕15g，蝉衣15g，黄芪10g，当归25g，西红花25g，芡实20g，前胡10g，桂枝35g，甘草5g，麝香8g，冰片5g，桃仁20g。
实施例4
一种治疗肾功能不全引起的阴部疼痛的中药组合物，是由下述重量份的药材制备而成：海马45g，龟板32g，鳖甲28g，地龙22g，全蝎18g，白僵蚕22g，蝉衣8g，黄芪18g，当归18g，西红花32g，芡实12g，前胡18g，桂枝28g，甘草12g，麝香4g，冰片12g，桃仁12g。
实施例5
一种治疗肾功能不全引起的阴部疼痛的中药组合物，是由下述重量份的药材制备而成：海马55g，龟板28g，鳖甲32g，地龙18g，全蝎22g，白僵蚕18g，蝉衣12g，黄芪12g，当归22g，西红花28g，芡实18g，前胡12g，桂枝32g，甘草8～12g，麝香4～6g，冰片8～12g，桃仁12～18g。
上述实施例1-5的中药组合物酊剂的制备方法：按所述配比称取海马、龟板、鳖甲、地龙、全蝎、白僵蚕、蝉衣、黄芪、当归、西红花、芡实、前胡、桂枝、甘草、麝香、冰片、桃仁。
混合后，通过采用高温或紫外线或消毒液对药物原料进行消毒灭菌，然后放置在平板上，经阳光曝晒，使药物原料充分干燥。在干燥处理后，利用超细打碎机，对药物原料混合后进行打碎，并碾磨成粉。
将打碎后的药物原料放入一容器中，再往容器中倒入相当于药物原料6倍重量、体积浓度为60％的白酒，在室内阴凉处放置2天，期间不停地搅拌容器内的药物原料，直至药物原液形成具有上清液层和沉淀层的药物原液。此时将容器内的上清液原液倒出，放置在一个新容器内备用。
往装有药物原料沉淀层的容器中，倒入相当于沉淀层2.5倍重量、体积浓度为75％的医用酒精，期间经常搅拌该混合液。浸泡5-7天后，再次得到具有分层明显的上清液层和沉淀层。此时再次倒出上清液原液，选择一个新的容器备用。
将经过两次萃取后的上清液原液倒入一个新容器中混合，形成成品药液，将成品药液经过医用筛网过滤后，装入金属铝罐中，密封后便可得到经络通中药组合物酊剂。
应用实施例
本发明治疗由于肾功能不全引起的阴部疼痛的疗效分析：
一、选择病例标准：
由于肾功能不全引起的少腹痛、会阴痛、腰骶部痛、鼠蹊部痛、睾丸痛患者。其中，年龄分布20～30岁32％，30～40岁占42％，40～50岁占16％，病程小于6个月的占15％，病程大于6个月的占52％，在于24个月的占33％。
二、本发明中实施例1、2、3、4、5采用以下治疗方案治疗
将已经灌装好的本产品、每日5次、一次2毫升、喷于扭伤的关节部位，7天为1疗程。可连续使用1-4个疗程。
三、疗效评定标准：
痊愈：症状完全消失，无任何不适症状；
好转：症状明显减轻，或部分症状消失，需继续治疗；
无效：症状未有任何改善，甚而有加重之趋势。
经临床试验，结果如下：使用本发明实施例1、2、3、4、5中治疗方案的中药组合物酊剂，每组患者50例，每日5次，一次2毫升，喷于阴部疼痛部位。7天为1疗程，针对病人身体情况，可连续1-4个疗程，并跟踪观察疗效。其中治愈30例，好转18例，无效2例。经过2个疗程后，病人无任何不良反应，各项肝肾功能检测未发现异常。临床统计结果见表1：
表1临床统计比较
由以上数据可知，本发明药物组合物治疗由于肾功能不全引起阴部疼痛，治疗有效率不低为94％。并对患者复发率进行跟踪观察，治疗组的复发率仅为5％，明显低于采用西抗生素治疗的复发率。
以上所述仅为本发明的较佳实施例而已，并不用以限制本发明，凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。
Claims (3)
1.一种治疗肾功能不全引起的阴部疼痛的中药组合物，其特征在于是由下述重量份的药材制备而成：海马40～60份，龟板25～35份，鳖甲25～35份，地龙15～25份，全蝎15～25份，白僵蚕15～25份，蝉衣5～15份，黄芪10～20份，当归15～25份，西红花25～35份，芡实10～20份，前胡10～20份，桂枝25～35份，甘草5～15份，麝香3～8份，冰片5～15份，桃仁10～20份。
2.根据权利要求1所述的一种治疗肾功能不全引起的阴部疼痛的中药组合物，其特征在于是由下述重量份的药材制备而成：海马45～55份，龟板28～32份，鳖甲28～32份，地龙18～22份，全蝎18～22份，白僵蚕18～22份，蝉衣8～12份，黄芪12～18份，当归18～22份，西红花28～32份，芡实12～18份，前胡12～18份，桂枝28～32份，甘草8～12份，麝香4～6份，冰片8～12份，桃仁12～18份。
3.根据权利要求1所述的一种治疗肾功能不全引起的阴部疼痛的中药组合物，其特征在于是由下述重量份的药材制备而成：海马50份，龟板30份，鳖甲30份，地龙20份，全蝎20份，白僵蚕20份，蝉衣10份，黄芪15份，当归20份，西红花30份，芡实15份，前胡15份，桂枝30份，甘草10份，麝香5份，冰片10份，桃仁15份。
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