CN106265369A - A kind of antiallergic composition and a kind of skin nursing products - Google Patents
A kind of antiallergic composition and a kind of skin nursing products Download PDFInfo
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- CN106265369A CN106265369A CN201610872549.9A CN201610872549A CN106265369A CN 106265369 A CN106265369 A CN 106265369A CN 201610872549 A CN201610872549 A CN 201610872549A CN 106265369 A CN106265369 A CN 106265369A
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- antiallergic composition
- antiallergic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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Abstract
The invention provides a kind of antiallergic composition, it includes Europe HUOXUEDAN extract, Herba portulacae extract and auxiliary agent, further, described antiallergic composition includes the auxiliary agent of Herba portulacae extract and surplus of Europe HUOXUEDAN extract, 0.5～5.0wt% of 0.5～5.0wt%.The application by add in antiallergic composition Europe HUOXUEDAN extract with Herba portulacae extract so as to get compositions there is preferable antiallergic effect；Further, compound, further increase the antiallergic effect of compositions.Present invention also provides a kind of skin nursing products.
Description
Technical field
The present invention relates to technical field of skin care, particularly relate to a kind of antiallergic composition and a kind of skin nursing products.
Background technology
Along with growth in the living standard, the use of cosmetics is more and more extensive.Cosmetics quality on market is irregular not
Together, a lot of products not only can not play maintenance effect, is easily caused allergy on the contrary.Meanwhile, also having a lot of people is sensitivity skin,
Be easily subject to the stimulation of various factors and produce the symptoms such as twinge, calcination, pruritus, and with slight desquamation, erythema, be dried
Deng.Above-mentioned skin problem is all allergic phenomena, and skin allergy has a strong impact on the comfortable of people and look.Existing antiallergic
The most DeGrain of cosmetics, therefore, studies the compositions that a kind of antiallergic effect is good, is problem demanding prompt solution.
Europe HUOXUEDAN has another name called Germany Herba Menthae, money Herba Menthae, originates in Europe and North America, INCI entitled Europe HUOXUEDAN
(GLECHOMA HEDERACEA) extract.Europe HUOXUEDAN contains abundant ursolic acid, left-handed menthone, pulegone, β paddy steroid
Alcohol, succinic acid, several amino acids and vitamin C.Europe HUOXUEDAN is currently used primarily in clearing heat and freeing strangury, cholagogic and lithagogue and tune of invigorating blood circulation
Warp, yet there are no the report for skin care item.
Summary of the invention
Present invention solves the technical problem that and be to provide a kind of antiallergic composition, the antiallergic composition that the application provides
As skin care item, there is anti-allergic effects.
In view of this, this application provides a kind of antiallergic composition, including: Europe HUOXUEDAN extract, Herba Portulacae are extracted
Thing and auxiliary agent.
Preferably, the content of described Europe HUOXUEDAN extract is 0.5wt%～5.0wt%, described Herba portulacae extract
Content is 0.5wt%～5.0wt%, and surplus is auxiliary agent.
Preferably, in terms of the percentage by weight of described antiallergic composition, described auxiliary agent includes: 0.1～the propylene of 0.5%
Acyl dimethyltaurine ammonium/VP copolymer, 0.01～the methyl hydroxybenzoate of 0.2%, 1.0～the glycerol of 6.0%, 1.0～6.0%
Butanediol, 0.01～the allantoin of 0.2%, 0.01～the hyaluronate sodium of 0.1%, 1.0～the trehalose of 3.0%, 0.6～
First component of 1.0%, the water of surplus；Described first component is by 85～the phenoxyethanol of 90% and 10～the ethylhexyl of 15%
Glycerol forms.
Preferably, the content of described Europe HUOXUEDAN extract is 1.0wt%～3.5wt%.
Preferably, the content of described Europe HUOXUEDAN extract is 1.5wt%～2.5wt%.
Preferably, the content of described Herba portulacae extract is 1.2wt%～4.0wt%.
Preferably, the content of described Herba portulacae extract is 1.5wt%～2.5wt%.
Preferably, the preparation method of described antiallergic composition comprises the following steps:
A phase raw material is mixed, heats up after stirring, obtain the first mixture；Described A phase raw material includes water, glycerol, fourth two
Alcohol, AVC, hyaluronate sodium, trehalose, methyl hydroxybenzoate and allantoin；
Add the mixing of B phase raw material when described first mixture is cooled to less than 45 DEG C, obtain antiallergic composition；Institute
State B phase raw material and include Europe HUOXUEDAN extract, Herba portulacae extract, phenoxyethanol and Sensiva SC50, obtain antiallergic group
Compound.
Preferably, obtaining in the first mixture step, the temperature of described intensification is 80～85 DEG C, the insulation after described intensification
Time time is 10～20min.
Present invention also provides a kind of skin nursing products, including the antiallergic composition described in such scheme.
This application provides a kind of antiallergic composition, comprising: Europe HUOXUEDAN extract, Herba portulacae extract with help
Agent；Further, described antiallergic composition includes the Europe HUOXUEDAN extract of 0.5wt%～5.0wt%, 0.5wt%～
The Herba portulacae extract of 5.0wt%, surplus is auxiliary agent.The application by adding Herba portulacae extract and Europe HUOXUEDAN extract,
Make compositions have preferable antianaphylaxis, further, Herba portulacae extract is compounded with Europe HUOXUEDAN extract, makes
Europe HUOXUEDAN extract can farthest suppress the transmission of inflammatory mediator, effectively suppresses release and the suppression TRPV1 of histamine
Process LAN, thus reach optimal antiallergic effect.
Detailed description of the invention
In order to be further appreciated by the present invention, below in conjunction with embodiment, the preferred embodiment of the invention is described, but
Should be appreciated that these describe simply as to further illustrate the features and advantages of the present invention rather than to the claims in the present invention
Limit.
The embodiment of the invention discloses a kind of antiallergic composition, including: Europe HUOXUEDAN extract, Herba portulacae extract with
Auxiliary agent.
The invention provides a kind of antiallergic composition, it includes Europe HUOXUEDAN extract, Herba portulacae extract and auxiliary agent,
By add said components so as to get compositions there is preferable antiallergic effect.
In the application, the INCI entitled Europe HUOXUEDAN extract of Europe HUOXUEDAN, it is Labiatae Glechoma, perennial grass
This.Originate in Europe, North America.Containing volatile oil 0.03%～0.20% in the fresh grass of Europe HUOXUEDAN, oil is led containing left-handed pine with Camphor tree ketone, and
Containing left-handed menthone, pulegone and other terpene compounds on a small quantity；Another containing tannin 3%～7%, Saponin, resin, Folium Vaccinii vitis-idaeae
The raw C of acid, Sitosterolum, Palmic acid, succinic acid, several amino acids and dimension.The content of herein described Europe HUOXUEDAN extract is excellent
Elect 0.5wt%～5.0wt% as, in an embodiment, the content of described Europe HUOXUEDAN extract be more preferably 1.0wt%～
3.5wt%, in an embodiment, the content of described Europe HUOXUEDAN extract is more preferably 1.5wt%～2.5wt%.
Herba portulacae extract is INCI name, and it is the extract of Herba Portulacae.Herba Portulacae is annual herb, Herb without hair,
It all produces in China various places, north and south, is born in vegetable garden, farmland, roadside, for field common weed.Herba Portulacae contains abundant dihydroxy second
The nutrient substance such as amine, malic acid, glucose, calcium, phosphorus, ferrum, vitamin E, carotene, vitamin B and vitamin C.The application
Described in the content of Herba portulacae extract be preferably 0.5wt%～5.0wt%, in an embodiment, described Herba portulacae extract
Content is more preferably 1.2wt%～4.0wt%, and in an embodiment, the content of described Herba portulacae extract is more preferably 1.5wt%
～2.5wt%.
Above-mentioned Europe HUOXUEDAN extract all carries according to technological means well known to those skilled in the art with Herba portulacae extract
Take, this application is had no particular limits.
Also including auxiliary agent in herein described antiallergic composition, what described auxiliary agent was well known to those skilled in the art helps
Agent, has no particular limits this application, example, in terms of the percentage by weight of described antiallergic composition, and described auxiliary agent
Including 0.1～the AVC of 0.5%, 0.01～the methyl hydroxybenzoate of 0.2%, 1.0～
The glycerol of 6.0%, 1.0～the butanediol of 6.0%, 0.01～the allantoin of 0.2%, 0.01～the hyaluronate sodium of 0.1%,
1.0～the trehalose of 3.0%, 0.6～first component of 1.0%, the water of surplus；Described first component is by 85～the benzene oxygen of 90%
Ethanol and 10～15% Sensiva SC50 composition.Above-mentioned auxiliary agent can add one in antiallergic composition, it is also possible to
Add multiple, this application is had no particular limits.
Preferably, the content of described AVC be preferably 0.1～
0.3wt%, the content of described methyl hydroxybenzoate is preferably 0.05～0.15wt%, the content of described glycerol be preferably 1.5～
5.0wt%, the content of described butanediol is preferably 2.5～5.0wt%, the content of described allantoin be preferably 0.03～
0.12wt%, the content of described hyaluronate sodium is preferably 0.03～0.08wt%, the content of described trehalose be preferably 1.5～
2.5wt%, the content of described first component is preferably 0.6～0.8wt%.
The preparation method of described antiallergic composition is had no particular limits by the application, ripe according to those skilled in the art
Prepared by the mode known.Example, the preparation process of described antiallergic composition particularly as follows:
A phase raw material is mixed, heats up after stirring, obtain the first mixture；Described A phase raw material includes water, glycerol, fourth two
Alcohol, AVC, hyaluronate sodium, trehalose, methyl hydroxybenzoate and allantoin；
Add the mixing of B phase raw material when described first mixture is cooled to less than 45 DEG C, obtain antiallergic composition；Institute
State B phase raw material and include Europe HUOXUEDAN extract, Herba portulacae extract, phenoxyethanol and Sensiva SC50, obtain antiallergic group
Compound.
In above process, described A phase raw material preferably mixes in vacuum emulsification pot, and the temperature of described intensification is 80
～85 DEG C, the temperature retention time after described intensification is preferably 10～20min.Formula at raw material described in preparation process forms above-mentioned
Have been carried out explanation, the most no longer repeat.
Present invention also provides a kind of skin nursing products, it includes the antiallergic composition described in such scheme.
Described skin nursing products can be used for skin of face, it is also possible to for body skin, to this application the most especially
Restriction.Described skin nursing products can be emulsion, it is also possible to for frost, has no particular limits this application.
The present invention, by Herba portulacae extract and Europe HUOXUEDAN extract being compounded according to a specific ratio, makes Europe invigorate blood circulation
The red transmission that can suppress inflammatory mediator to the full extent, can effectively suppress release and the suppression TRPV1 process LAN of histamine, thus reach
To optimal antiallergic effect.Result of the test shows, the collaborative anti-mistake of Europe HUOXUEDAN extract collocation Herba portulacae extract product
Quick effect is notable, and Europe HUOXUEDAN extract can be obviously improved the mildness of product.
In order to be further appreciated by the present invention, the antiallergic composition provided the present invention below in conjunction with embodiment is carried out in detail
Illustrating, protection scope of the present invention is not limited by the following examples.
In following example, raw material is commercially available prod or prepares according to method well known to those skilled in the art.
Embodiment 1
(1) various raw materials in precise formula, hold with vessel that are clean and that disinfect；
(2) A phase raw material is added in vacuum emulsification pot, after stirring is warming up to 80～85 DEG C, stir, be incubated 20
After minute, opening cooling water temperature, described A phase raw material includes that water, glycerol, butanediol, ammonium acryloyldime-thyltaurate/VP are common
Polymers, hyaluronate sodium, trehalose, methyl hydroxybenzoate and allantoin；
(3) it is cooled to the mixture that step (2) obtains when less than 45 DEG C add B phase raw material, goes out after stirring
Material, standing, described B phase raw material includes Europe HUOXUEDAN (GLECHOMA HEDERACEA) extract, Herba Portulacae (PORTULACA
OLERACEA) extract, phenoxyethanol and Sensiva SC50；
(4) compositions step (3) obtained is after the assay was approved, fill, packaging, coding；After the assay was approved, warehouse-in,
To antiallergic perception compositions.
In the present embodiment, the concrete formula of above-mentioned raw materials is as shown in table 1.
The formulation data table (wt%) of table 1 embodiment 1 antiallergic composition
Embodiment 2
Preparation method is same as in Example 1, and difference is: the proportioning of the raw material of antiallergic composition is different, concrete such as table 2
Shown in.
The formulation data table (wt%) of the antiallergic composition of table 2 embodiment 2
Embodiment 3
Preparation method is same as in Example 1, and difference is: the proportioning of the raw material of antiallergic composition is different, concrete such as table 3
Shown in.
The formulation data table (wt%) of the antiallergic composition of table 3 embodiment 3
Comparative example 1
Preparation method is same as in Example 1, and difference is: the proportioning of the raw material of antiallergic composition is different, concrete such as table 4
Shown in.
The formulation data table (wt%) of the antiallergic composition of table 4 comparative example 1
Comparative example 2
Preparation method is same as in Example 1, and difference is: the proportioning of the raw material of antiallergic composition is different, concrete such as table 5
Shown in.
The formulation data table (wt%) of the antiallergic composition of table 5 comparative example 2
Embodiment 4
The physical and chemical index test result of comparative example and embodiment is as follows:
1, outward appearance: water white transparency mucus；
2, pH value: 5.5-6.8；
3, heat-resistant stability investigates (48 DEG C × 24h): qualified；
4, cold-resistant study on the stability (-15 DEG C × 24h): qualified；
In order to prove effect of this product, having looked for 200 female volunteers, the testing time is 4 weeks, has carried out following examination
Test:
1, Subject Population: totally 200 (point 40 volunteers of 5 groups of each embodiments, do not have juxtaposition),
1) age is between 22 to 40 years old；
2) experimenter can be coordinated very well, regularity in one's life can be kept during studying, during test, not use other to change
Cosmetic；
2, method of testing:
Comparative example 1, comparative example 2, embodiment 1, embodiment 2, embodiment 3 extract 40 volunteers respectively；Using method is:
Sooner or later, after face cleaning, take and be applied to facial massage in right amount to absorbing, after using 4 weeks continuously, relative analysis evaluate the various embodiments described above and
The antiallergic effect of comparative example cosmetics.Wherein, described antiallergic effect for skin is itched, sensation of pricking, erythema, tiny squama
Deng improvement situation.
3, test result:
This test sends 200 parts of sample altogether, and after the continuous surrounding of volunteer uses comparative example and embodiment, relative analysis is commented
Valency the various embodiments described above and the antiallergic effect of comparative example cosmetics, the results are shown in Table 6.
The antiallergic effect tables of data of the compositions that table 6 embodiment provides with comparative example
The antiallergic perception compositions of embodiment 1～3 with the addition of the Europe HUOXUEDAN (GLECHOMA of different proportion
HEDERACEA) extract and Herba Portulacae (PORTULACA OLERACEA) extract；The antiallergic perception compositions of comparative example 1 adds
Add Herba Portulacae (PORTULACA OLERACEA) extract, the antiallergic perception compositions of comparative example 2 with the addition of Europe HUOXUEDAN
(GLECHOMA HEDERACEA) extract.As shown in table 6, knowable to test result: after using 4 weeks, experimenter can experience
Skin is itched by the cosmetics using embodiment 1～3, the improvement situation of sensation of pricking, erythema, tiny squama etc. is obvious, and effect is better than
It is used alone Europe HUOXUEDAN (GLECHOMA HEDERACEA) extract or Herba Portulacae (PORTULACA OLERACEA) extract,
Illustrate that Europe HUOXUEDAN (GLECHOMA HEDERACEA) extract collocation Herba Portulacae (PORTULACA OLERACEA) extract is assisted
Notable with effect, the antiallergic effect of product is obviously improved.The explanation of above example is only intended to help to understand the present invention's
Method and core concept thereof.It should be pointed out that, for those skilled in the art, without departing from the principle of the invention
On the premise of, it is also possible to the present invention is carried out some improvement and modification, and these improve and modification also falls into the claims in the present invention
Protection domain in.Described above to the disclosed embodiments, makes professional and technical personnel in the field be capable of or uses this
Invention.Multiple amendment to these embodiments will be apparent from for those skilled in the art, herein institute
The General Principle of definition can realize without departing from the spirit or scope of the present invention in other embodiments.Therefore,
The present invention is not intended to be limited to the embodiments shown herein, and is to fit to special with principles disclosed herein and novelty
The widest scope that point is consistent.
Claims (10)
1. an antiallergic composition, including: Europe HUOXUEDAN extract, Herba portulacae extract and auxiliary agent.
Antiallergic composition the most according to claim 1, it is characterised in that the content of described Europe HUOXUEDAN extract is
0.5wt%～5.0wt%, the content of described Herba portulacae extract is 0.5wt%～5.0wt%, and surplus is auxiliary agent.
Antiallergic composition the most according to claim 1 and 2, it is characterised in that with the weight of described antiallergic composition
Percentages, described auxiliary agent includes: 0.1～the AVC of 0.5%, 0.01～0.2%
Methyl hydroxybenzoate, 1.0～the glycerol of 6.0%, 1.0～the butanediol of 6.0%, 0.01～the allantoin of 0.2%, 0.01～0.1%
Hyaluronate sodium, 1.0～the trehalose of 3.0%, 0.6～first component of 1.0%, the water of surplus；Described first component by
85～the phenoxyethanol of 90% and 10～15% Sensiva SC50 composition.
Antiallergic composition the most according to claim 1 and 2, it is characterised in that the content of described Europe HUOXUEDAN extract
For 1.0wt%～3.5wt%.
Antiallergic composition the most according to claim 1 and 2, it is characterised in that the content of described Europe HUOXUEDAN extract
For 1.5wt%～2.5wt%.
Antiallergic composition the most according to claim 1 and 2, it is characterised in that the content of described Herba portulacae extract is
1.2wt%～4.0wt%.
Antiallergic composition the most according to claim 1 and 2, it is characterised in that the content of described Herba portulacae extract is
1.5wt%～2.5wt%.
Antiallergic composition the most according to claim 3, it is characterised in that the preparation method bag of described antiallergic composition
Include following steps:
A phase raw material is mixed, heats up after stirring, obtain the first mixture；Described A phase raw material include water, glycerol, butanediol, third
Alkene acyl dimethyltaurine ammonium/VP copolymer, hyaluronate sodium, trehalose, methyl hydroxybenzoate and allantoin；
Add the mixing of B phase raw material when described first mixture is cooled to less than 45 DEG C, obtain antiallergic composition；Described B
Phase raw material includes Europe HUOXUEDAN extract, Herba portulacae extract, phenoxyethanol and Sensiva SC50, obtains antiallergic combination
Thing.
Antiallergic composition the most according to claim 8, it is characterised in that obtain in the first mixture step, described liter
The temperature of temperature is 80～85 DEG C, and the temperature retention time time after described intensification is 10～20min.
10. skin nursing products, including the antiallergic composition described in any one of claim 1～9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610872549.9A CN106265369A (en) | 2016-09-29 | 2016-09-29 | A kind of antiallergic composition and a kind of skin nursing products |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610872549.9A CN106265369A (en) | 2016-09-29 | 2016-09-29 | A kind of antiallergic composition and a kind of skin nursing products |
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| CN106265369A true CN106265369A (en) | 2017-01-04 |
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ID=57716082
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| CN201610872549.9A Pending CN106265369A (en) | 2016-09-29 | 2016-09-29 | A kind of antiallergic composition and a kind of skin nursing products |
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| CN105030621A (en) * | 2015-08-28 | 2015-11-11 | 青岛海之源智能技术有限公司 | Moisturizing and acne removing toner and preparing method thereof |
| CN105078829A (en) * | 2015-08-28 | 2015-11-25 | 青岛海之源智能技术有限公司 | Chinese medicinal acne-removing face cream and preparation method thereof |
| CN105168027A (en) * | 2015-08-14 | 2015-12-23 | 百芮生物科技（上海）有限公司 | Essence added with natural anti-allergy repair combination and preparation method of essence |
| CN105434282A (en) * | 2015-12-31 | 2016-03-30 | 天津达仁堂京万红药业有限公司 | Moisturizing and nourishing toner and preparation method thereof |
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2016
- 2016-09-29 CN CN201610872549.9A patent/CN106265369A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101677912A (en) * | 2007-05-11 | 2010-03-24 | 希格马托制药工业公司 | Gel useful for the delivery of cosmetic active ingredients |
| CN105168027A (en) * | 2015-08-14 | 2015-12-23 | 百芮生物科技（上海）有限公司 | Essence added with natural anti-allergy repair combination and preparation method of essence |
| CN105030621A (en) * | 2015-08-28 | 2015-11-11 | 青岛海之源智能技术有限公司 | Moisturizing and acne removing toner and preparing method thereof |
| CN105078829A (en) * | 2015-08-28 | 2015-11-25 | 青岛海之源智能技术有限公司 | Chinese medicinal acne-removing face cream and preparation method thereof |
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Application publication date: 20170104 |