CN104873437A - Fructus-rosae-laevigatae skin cream and preparation method thereof - Google Patents
Fructus-rosae-laevigatae skin cream and preparation method thereof Download PDFInfo
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- CN104873437A CN104873437A CN201510301262.6A CN201510301262A CN104873437A CN 104873437 A CN104873437 A CN 104873437A CN 201510301262 A CN201510301262 A CN 201510301262A CN 104873437 A CN104873437 A CN 104873437A
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Abstract
The invention discloses a fructus-rosae-laevigatae skin cream and a preparation method thereof. According to the fructus-rosae-laevigatae skin cream and the preparation method thereof, comprehensive effective constituents of fructus rosae laevigatae are directly extracted with water; the comprehensive effective constituents are added into a water phase and are mixed and emulsified with an oil phase including other constituents at the same time; a finished product meets relevant quality detection requirements. The fructus-rosae-laevigatae skin cream becomes a favorable preparation applied to skin care. By using the method provided by the invention, the problem that the fructus rosae laevigatae is applied to the health protection of a skin can be scientifically solved; further, the cleaning is easy; the pollution is free. The method can be used for large-lot production, and can be popularized and applied to large-area skin care.
Description
Technical field
The invention belongs to and adopt medicinal plants, Chinese crude drug to prepare protective skin cream technical field, relating to the cream of Fructus Rosae Laevigatae, is a kind of preparation method of Fructus Rosae Laevigatae protective skin cream in particular.
Background technology
Fructus Rosae Laevigatae
rosa laevigatamichx. be a kind of traditional bulk medicinal materials, the history of being used as medicine in China existing more than 2,000 years, has higher medical value and economic worth.Fructus Rosae Laevigatae
gastrodia elatabl. wild distribution is wide, also easily artificial culture breeding, total output is large, effective ingredient enriches, main containing polysaccharide, flavone, tannin, several amino acids and the various trace elements such as selenium, zinc, and all exist with organic form, very easily absorb by human body, there are some researches prove, Fructus Rosae Laevigatae not only has extra-nutrition, Thyme Extract, and significantly can remove ultra-oxygen anion free radical, suppress the destruction of hydroxy radical cell membrane and the formation of the haemolysis that causes and lipid peroxidation product, thus there is significant antioxidation and function of anti-skin aging.Current Application and Development relates generally to the fields such as medicine food medicated cigarette washing, and have no the report that it can be used as protective skin cream aspect, its Application and Development potentiality are quite large.The invention belongs to the frontier preparation of Fructus Rosae Laevigatae dermal application, larger application demand will be obtained, thus continue and play the due value of Fructus Rosae Laevigatae.
Summary of the invention
Preparation method of the present invention, the effective ingredient that direct water extraction Fructus Rosae Laevigatae is comprehensive, make an addition to aqueous phase and with the simultaneously mixing and emulsifying of the oil phase containing other compositions, finished product meets correlated quality testing requirement.
The invention provides following technical scheme for achieving the above object:
Formula
A oil phase w (mass percent)
Stearic acid 4.2-4.8%, octadecanol 2.2-2.8%,
Hexadecanol 2.2-2.8%, white oil 2.8-3.5%,
Tween-60 0.47-0.53%, lanoline 1.0-1.5%, olive oil 0.48-0.52%
B aqueous phase w (mass percent)
Fructus Rosae Laevigatae extract 3.5-4.5%, glycerol 6.3-6.8%, triethanolamine 0.28-0.33%,
Distilled water 70-80%, jasmin essence 0.1-0.3%,
Bronopol 0.02-0.05%, propylparaben 0.1-0.2%
When developing cosmetic formulations, contrast through multiple formulations, select excellent experiment, finally determine that this product is using stearic acid and triethanolamine as emulsifying agent, surface active agent tween-60 plays the effect increasing emulsifying effectiveness, add hexadecanol, octadecanol is as emulsion adjuvant, white oil is used as emollient and wetting agent, lanoline has the special role of horny layer softening cortex, olive oil energy Palmitoleic Acid, good convergence and permeability is had to skin, using glycerol as wetting agent, and increase the content of glycerin components and water, the trophism of cosmetics can be made, permeability is better, reduce greasy feeling, the moisturizing of skin is also improved, feel comfortable during use, adopt compound preservative (with Bronopol, propylparaben) prophylaxis of microbial pollution.
Note: Fructus Rosae Laevigatae extract refers to gets Fructus Rosae Laevigatae dry fruit and the appropriate heating extraction of water three times, mixing evaporation and concentration respectively, being concentrated into the thick paste of relative density for obtaining during 1.20-1.40 by after three extracting liquid filterings.
Preparation method
Oil phase and aqueous phase are placed in electric-heated thermostatic water bath respectively and stir, be heated to 90 DEG C and melt completely after in homogeneous phase, aqueous phase about 90 DEG C insulation 20min, filters after sterilizing respectively.And then at this temperature, while aqueous phase stirs, slowly oil phase is added stirring and emulsifying, and Keep agitation 1h.Add jasmin essence, Bronopol, propylparaben during slow cooling to 45 DEG C, continue to stir, when temperature is down to 35 DEG C, stop stirring, static, cooling, obtains newborn creamy product, take a sample to check (
table 1).
table 1finished product detection result
Emulsifying agent is on the impact of whitening skin-protection cream pH value
Beautifying and skin-protecting cream system cream kind cosmetics, according to
countrycosmetics quality examination criteria, its pH value is equal conformance with standard between 4-9.Emulsifying agent triethanolamine has good emulsifiability, but it to the pH value of product have a certain impact (
fig. 8), because surface active agent tween-60 also plays the effect strengthening emulsifying effectiveness, so the stability influence of less consumption to whole cream of fixing triethanolamine is little, to triethanolamine consumption less in aqueous phase, can supplement with the glycerol with skin moistening and moisture-keeping efficacy, the consumptions such as laboratory observation Fructus Rosae Laevigatae extract, glycerol, triethanolamine on the impact of finished product stability (
table 2).
table 2made prescription for skin cream (mass percent)
Through experimentation, Fructus Rosae Laevigatae extract 3.5%, 4.0%, 6.0%, glycerol 6.5%, triethanolamine 0.31%, cream formulations finished product stability is all good, and other add composition in amount ranges of the present invention, and the finished product stability carrying out preparing is constant.
The invention belongs to oil-in-water type cream cosmetic product, aqueous phase accounts for 70%-90%, and oil phase accounts for 30%-10%.
table 2middle 4# formula: aqueous phase accounts for 85%, and oil phase accounts for 15%, belongs to the oil-in-water type cream cosmetic product being with weak oiliness, there is the nutrition skin moistening effect of refreshing sense, and easy cleaning, pollution-free, the people being suitable for any skin quality uses, and is particularly useful for the active youngster of skin secretion and oily skin person.
Operation notice
(1) in the preparation of Fructus Rosae Laevigatae whitening skin-protection cream, heat 90 DEG C and its solid is melted, prevent from finished product, occurring particle phenomenon; Essence adds fashionable, and be advisable at 40 DEG C-45 DEG C, temperature is too high, and essence volatilization loss is large, and temperature is too low, and essence can add in the oil phase of Emulsion.
(2) in emulsion process, the speed of stirring will be first quick and back slow.After temperature reduces, necessary slow-down, because excessive velocities, can make the bubble bringing Emulsion into not easily discharge, thus affect the fine and smooth degree of Emulsion.
(3) in preparation process, strict production control environment, accomplishes aseptic and keeps away bacterium operation, in order to avoid make bacteria containing amount in protective skin cream too high; Meanwhile, select operation tool and container, strictly limit the content of the metals such as lead, hydrargyrum, copper, ferrum, aluminum, improve stability and the safety of product use.
Human body skin experiment and trial effect (
fig. 1-7)
Get four layers of hospital gauze and be cut into 1c ㎡, the protective skin cream coating development is about 40mg, is attached to inner forearm and covers polyacrylic film, fixing with medical proof fabric, and duration of test trier not edible maror, irritable food, test position does not get wet.Open observation after 24h, test position is all aobvious negative, namely occurs without erythema, pimple, edema or other allergic phenomenas.
The protective skin cream of development is applied to face, and skin is felt salubrious and is moistened.Trier feels that skin is all very comfortable for all day after using, and after using a period of time, skin improves significantly, and has the sensation that water is tender, pale.Preliminary use shows, this protective skin cream can desalinate the pigment of skin, makes the whitening of skin nature glossy.
The good effect that Fructus Rosae Laevigatae whitening skin-protection cream disclosed by the invention has compared with existing product is:
(1) Fructus Rosae Laevigatae whitening skin-protection cream there is skin care, sterilize, brighten, moisturizing, crease-resistant, antiinflammatory, the special efficacy such as antipruritic, trophocyte.
(2) Fructus Rosae Laevigatae whitening skin-protection cream can improve the metabolism of skin, softening skin, plays anti-ageing anti-old effect
(3) Fructus Rosae Laevigatae whitening skin-protection cream have than vague generalization cosmetic action temperature and, little, the safety high of zest.And by the development to Fructus Rosae Laevigatae whitening skin-protection cream, we feel that it is practical, coming for preparing cosmetics with Chinese herbal medicine.
Accompanying drawing illustrates:
Fig. 1 is skin protection cream 1 of the present invention;
Fig. 2 is skin protection cream 2 of the present invention;
Fig. 3 is skin protection cream 3 of the present invention;
Fig. 4 is human body skin experiment 1;
Fig. 5 is human body skin experiment 2;
Fig. 6 is human body skin experiment 3;
Fig. 7 is human body skin trial effect;
Fig. 8 is that emulsifying agent triethanolamine addition is on the impact of product pH value.
Specific embodiment
Below in conjunction with embodiment, the present invention is described further, and embodiment is only indicative, never means that it limits the scope of the invention by any way.Useful effect of the present invention is further illustrated below by way of Fructus Rosae Laevigatae protective skin cream embodiment.The used raw material such as stearic acid, triethanolamine, Tween-60, hexadecanol, octadecanol, white oil, lanoline, olive oil, glycerol, Bronopol, propylparaben, Fructus Rosae Laevigatae dry fruit is by commercially available.
Embodiment 1
Concrete formula:
A oil phase w (mass percent)
Stearic acid 4.2, octadecanol 2.2,
Hexadecanol 2.2, white oil 2.8,
Tween-60 0.47, lanoline 1.0, olive oil 0.48
B aqueous phase w (mass percent)
Fructus Rosae Laevigatae extract 3.5, glycerol 6.3, triethanolamine 0.28,
Distilled water 70, jasmin essence 0.1,
Bronopol 0.02, propylparaben 0.1
Wherein said Fructus Rosae Laevigatae extract refers to gets Fructus Rosae Laevigatae dry fruit and 70% water heating extraction three times, mixes evaporation and concentration respectively by after three extracting liquid filterings, be concentrated into relative density for 1.20 time the thick paste that obtains.
Preparation Fructus Rosae Laevigatae medicinal substances extract: get Fructus Rosae Laevigatae dry fruit, added water powder, heating extraction three times, mixes evaporation and concentration respectively by after three extracting liquid filterings, is concentrated into thick paste (relative density is 1.20).
Preparation method:
Oil phase and aqueous phase are placed in respectively in electric-heated thermostatic water bath and are heated with stirring to 90 DEG C and melt completely in after homogeneous phase, aqueous phase about 90 DEG C is incubated 20min, filters respectively after sterilizing.And then at this temperature, while aqueous phase stirs, being added in emulsion tank by oil phase is slowly stirred, and continues stirring 1 hour.Add jasmin essence, antiseptic Bronopol, propylparaben during slow cooling to 40 DEG C, continue to stir, when temperature is down to about 35 DEG C, stop stirring, static, cooling.
Get four layers of hospital gauze and be cut into 1c ㎡, the protective skin cream coating development is about 40mg, to be attached to inside volunteer skin of forearm and to cover polyacrylic film, fixing with medical proof fabric, during this, volunteer not edible maror, irritable food, is coated with protective skin cream position and does not get wet.Open observation after 24h, the skin being coated with protective skin cream is all aobvious negative, namely occurs without erythema, pimple, edema or other allergic phenomenas.
The protective skin cream of development is applied to face, and skin is felt salubrious and is moistened, and feels that skin is all very comfortable for all day, and after using a period of time, skin improves significantly, and has the sensation that water is tender, pale.Preliminary use shows, this protective skin cream can desalinate the pigment of skin, makes the whitening of skin nature glossy.
Embodiment 2
Concrete formula:
A oil phase w (mass percent)
Stearic acid 4.5, octadecanol 2.51,
Hexadecanol 2.5, white oil 3.1,
Tween-60 0.5, lanoline 1.2, olive oil 0.5
B aqueous phase w (mass percent)
Fructus Rosae Laevigatae extract 4.0, glycerol 6.5, triethanolamine 0.31,
Distilled water 75 jasmin essence 0.25, Bronopol 0.03, propylparaben 0.15
Wherein said Fructus Rosae Laevigatae extract refers to gets Fructus Rosae Laevigatae dry fruit and 75% water heating extraction three times, mixes evaporation and concentration respectively by after three extracting liquid filterings, be concentrated into relative density for 1.35 time the thick paste that obtains.
Preparation method:
Oil phase and aqueous phase are placed in respectively in electric-heated thermostatic water bath and are heated with stirring to 92 DEG C and melt completely in after homogeneous phase, aqueous phase about 92 DEG C is incubated 20min, filters respectively after sterilizing.And then at this temperature, while aqueous phase stirs, being added in emulsion tank by oil phase is slowly stirred, and continues stirring 1 hour.Add jasmin essence, antiseptic Bronopol, propylparaben during slow cooling to 42 DEG C, continue to stir, when temperature is down to about 35 DEG C, stop stirring, static, cooling.
Get four layers of hospital gauze and be cut into 1c ㎡, the protective skin cream coating development is about 40mg, to be attached to inside volunteer skin of forearm and to cover polyacrylic film, fixing with medical proof fabric, during this, volunteer not edible maror, irritable food, is coated with protective skin cream position and does not get wet.Open observation after 36h, the skin being coated with protective skin cream is all aobvious negative, namely occurs without erythema, pimple, edema or other allergic phenomenas.
The protective skin cream of development and certain brand protective skin cream commercially available are applied to volunteer face respectively simultaneously, this protective skin cream skin is felt salubrious and is moistened, and feel that skin is all very comfortable for all day, certain brand protective skin cream commercially available is without salubrious sense, and moisture feeling is also poor, this protective skin cream and using after a period of time, skin improves significantly, and has the sensation that water is tender, pale.And preliminary use shows, this protective skin cream can desalinate the pigment of skin, make the whitening of skin nature glossy.
Embodiment 3
Concrete formula:
A oil phase w (mass percent)
Stearic acid 4.8, octadecanol 2.8,
Hexadecanol 2.8, white oil 3.5,
Tween-60 0.53, lanoline 1.5, olive oil 0.52
B aqueous phase w (mass percent)
Fructus Rosae Laevigatae extract 4.5, glycerol 6.8, triethanolamine 0.33,
Distilled water 80, jasmin essence 0.3,
Bronopol 0.05, propylparaben 0.2
Wherein said Fructus Rosae Laevigatae extract refers to gets Fructus Rosae Laevigatae dry fruit and 80% water heating extraction three times, mixes evaporation and concentration respectively by after three extracting liquid filterings, be concentrated into relative density for 1.40 time the thick paste that obtains.
Preparation method:
Oil phase and aqueous phase are placed in respectively in electric-heated thermostatic water bath and are heated with stirring to 95 DEG C and melt completely in after homogeneous phase, aqueous phase about 95 DEG C is incubated 20min, filters respectively after sterilizing.And then at this temperature, while aqueous phase stirs, being added in emulsion tank by oil phase is slowly stirred, and continues stirring 1 hour.Add jasmin essence, antiseptic Bronopol, propylparaben during slow cooling to 45 DEG C, continue to stir, when temperature is down to about 35 DEG C, stop stirring, static, cooling.
Get four layers of hospital gauze and be cut into 1c ㎡, the protective skin cream coating development is about 40mg, to be attached to inside volunteer skin of forearm and to cover polyacrylic film, fixing with medical proof fabric, during this, volunteer not edible maror, irritable food, is coated with protective skin cream position and does not get wet.Open observation after 48h, the skin being coated with protective skin cream is all aobvious negative, namely occurs without erythema, pimple, edema or other allergic phenomenas.
The protective skin cream of development and certain brand protective skin cream commercially available are applied to volunteer face respectively simultaneously, this protective skin cream skin is felt salubrious and is moistened, and feel that skin is all very comfortable for all day, certain brand protective skin cream commercially available is without salubrious sense, and moisture feeling is also poor, this protective skin cream and using after a period of time, skin improves significantly, and has the sensation that water is tender, pale.And preliminary use shows, this protective skin cream can desalinate the pigment of skin, make the whitening of skin nature glossy.
Claims (4)
1. a Fructus Rosae Laevigatae protective skin cream, is characterized in that it is made up of following compositions:
A oil phase w (mass percent)
Stearic acid 4.2-14.8%, octadecanol 2.2-2.8%,
Hexadecanol 2.2-2.8%, white oil 2.8-3.5%,
Tween-60 0.47-0.53%, lanoline 1.0-1.5%, olive oil 0.48-0.52%
B aqueous phase w (mass percent)
Fructus Rosae Laevigatae extract 3.5-4.5%, glycerol 6.3-6.8%, triethanolamine 0.28-0.33%,
Distilled water 70-80%, jasmin essence 0.1-0.3%,
Bronopol 0.02-0.05%, propylparaben 0.1-0.2%
Wherein said Fructus Rosae Laevigatae extract refers to gets Fructus Rosae Laevigatae dry fruit and 70-80% water heating extraction three times, mixing evaporation and concentration respectively, being concentrated into the thick paste of relative density for obtaining during 1.20-1.40 by after three extracting liquid filterings.
2. the preparation method of Fructus Rosae Laevigatae protective skin cream described in claim 1, is characterized in that being undertaken by following step:
(1) oil phase and aqueous phase are placed in electric-heated thermostatic water bath respectively stir, be heated to 90 DEG C melt completely after in homogeneous phase, aqueous phase 90-95 DEG C of insulation 20min, filter respectively after sterilizing, then at 90-95 DEG C of temperature, while aqueous phase stirs, at leisure oil phase is added stirring and emulsifying, and Keep agitation 1h;
(2) add jasmin essence, Bronopol, propylparaben during slow cooling to 45 DEG C, continue to stir, when temperature is down to 35-40 DEG C, stop stirring, static, cooling, obtains newborn creamy product.
3. described in claim 1, Fructus Rosae Laevigatae protective skin cream is improving skin properties, makes the application of tender, the pale aspect of skin beauty water.
4. Fructus Rosae Laevigatae protective skin cream described in claim 1 is at elimination skin pigment, makes the application of the skin nature glossy aspect of whitening.
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105832578A (en) * | 2016-04-12 | 2016-08-10 | 天津大学 | Ginsenoside whitening and moisturizing cream and preparation method thereof |
CN107174551A (en) * | 2017-06-22 | 2017-09-19 | 西北大学 | Anti-oxidant face cream of Chinese gooseberry seed polyphenol and preparation method thereof |
CN109157447A (en) * | 2018-09-25 | 2019-01-08 | 任旻琼 | Application and preparation method of the Fructus Rosae Laevigatae extract in skin whitening, moisturizing anti-aging skin care product |
CN109260139A (en) * | 2018-11-08 | 2019-01-25 | 深圳市茵冠生物科技有限公司 | A kind of stem cell skin care item and preparation method thereof |
CN111991311A (en) * | 2020-08-29 | 2020-11-27 | 荣鼎(广东)生物科技有限公司 | Production process of olive oil-containing nano essence |
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JPH03275609A (en) * | 1990-03-23 | 1991-12-06 | Kose Corp | Skin cosmetic |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105832578A (en) * | 2016-04-12 | 2016-08-10 | 天津大学 | Ginsenoside whitening and moisturizing cream and preparation method thereof |
CN107174551A (en) * | 2017-06-22 | 2017-09-19 | 西北大学 | Anti-oxidant face cream of Chinese gooseberry seed polyphenol and preparation method thereof |
CN107174551B (en) * | 2017-06-22 | 2020-10-16 | 西北大学 | Kiwi fruit seed polyphenol antioxidant skin cream and preparation method thereof |
CN109157447A (en) * | 2018-09-25 | 2019-01-08 | 任旻琼 | Application and preparation method of the Fructus Rosae Laevigatae extract in skin whitening, moisturizing anti-aging skin care product |
CN109157447B (en) * | 2018-09-25 | 2021-10-26 | 任旻琼 | Application of cherokee rose fruit extract in whitening, moisturizing and anti-aging skin care product and preparation method thereof |
CN109260139A (en) * | 2018-11-08 | 2019-01-25 | 深圳市茵冠生物科技有限公司 | A kind of stem cell skin care item and preparation method thereof |
CN111991311A (en) * | 2020-08-29 | 2020-11-27 | 荣鼎(广东)生物科技有限公司 | Production process of olive oil-containing nano essence |
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Application publication date: 20150902 |