CN106237237A - A kind of Chinese medicine composition treating cyclomastopathy and preparation method thereof - Google Patents
A kind of Chinese medicine composition treating cyclomastopathy and preparation method thereof Download PDFInfo
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- CN106237237A CN106237237A CN201610733368.8A CN201610733368A CN106237237A CN 106237237 A CN106237237 A CN 106237237A CN 201610733368 A CN201610733368 A CN 201610733368A CN 106237237 A CN106237237 A CN 106237237A
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Abstract
The present invention provides a kind of Chinese medicine composition treating cyclomastopathy and preparation method thereof, belongs to technical field of Chinese medicines.It is made up of the raw material of following weight portion: Serissa foetida 15 30 parts, Herba Patriniae 5 10 parts, Semen Ricini 5 20 parts, Sanguis Draxonis 3 11 parts, Folium Symplocoris Caudatae 2 10 parts, Herba seu Flos Convolvuli arvensis 2 10 parts, Caulis Spatholobi 10 15 parts, Rhizoma Curcumae 10 15 parts, Semen Momordicae 10 15 parts, Fructus anethi 7 11 parts, soft Radix Bupleuri 9 21 parts, Fructus Toosendan 10 30 parts, Rhizoma Cyperi 15 20 parts, Thallus Laminariae (Thallus Eckloniae) 10 15 parts, Semen Vaccariae 15 parts, Fructus Liquidambaris 15 parts.This Chinese medicine composition treats cyclomastopathy by resolving depression eliminating stagnation, regulating blood circulation, the principle of the clear core of blood stasis dispelling, has instant effect, good effect, the advantage that has no side effect.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition treating cyclomastopathy and preparation side thereof
Method.
Background technology
Cyclomastopathy is women commonly encountered diseases and frequently-occurring disease, multiple with young and middle-aged women, especially with unmarried or do not give birth to, do not feed
Newborn and dysthymic women the most easily suffers from this disease.Cyclomastopathy is normal breast lobule physiological hypertrophy and subinvolution,
Mammary gland normal configuration gets muddled, and belongs to pathological proliferation, and it is a class disease of the most noninflammatory but also non-tumor.Cause of disease spiritedness because of
Element, bad life habits, diet are unreasonable.Direct stimulation can change human internal environment, thus affects hormonal system function,
The secretion causing a certain or several hormone occurs abnormal.The bad Nervous and Mental Factors such as spirit is excessively nervous, emotion is excessively exciting, all
The breast hyperplasia tissue that should restore may be made to can not get restoring or meromorphosis, in the course of time, just form cyclomastopathy,
And these bad direct stimulations also can increase the weight of existing cyclomastopathy symptom.Also have many anthropic factors and life style because of
Element, artificial abortion, fertility or fertility in more than 30 years old, not suckling, man and wife gets along well, and the breast of tension worn by health product containing hormone etc.
Cover, the medicated bra of tension is easily oppressed lymph and blood circulation, is all hindered Breast health.Additionally dietary structure is unreasonable, as fat is taken the photograph
Enter too much, the endocrine of ovary can be affected, strengthen the stimulation of estrogen on breast epithelial cell thus cause cyclomastopathy.Clinical
Show as main with mastalgia, lump etc., and how to change with menstrual cycle, feelings will, the factor such as overwork relevant.Typically giving birth to
The reason cycle occurs front obvious, can alleviate or disappear after end cycle.Severe patient can in rest pain, cause Ipsilateral shoulder,
Axillary fossa, flank, back pain.
This disease sickness rate the most increasingly became younger in the trend risen year by year, age in the last few years.Treat in the market
The drug main of cyclomastopathy to have the Chinese patent medicines such as breast peaceful granule, GUIZHI FULING JIAONANG, PINGXIAO JIA0NANG, and these Chinese patent medicine specific aims are not
By force, even mostly be the medicine for the treatment of gynecological multiple disease treatment tumor, double cyclomastopathy of controlling, or just for cyclomastopathy
A certain symptom or a certain pathology link, and expensive.
Summary of the invention
It is an object of the invention to: for the problem of above-mentioned existence, it is provided that a kind of Chinese medicine composition treating cyclomastopathy
And preparation method thereof, treat cyclomastopathy by resolving depression eliminating stagnation, regulating blood circulation, the principle of the clear core of blood stasis dispelling, there is instant effect, treatment
The advantage imitate, having no side effect.
According to the theory of the traditional Chinese medical science, the clinical manifestation of different pattern of syndrome cyclomastopathies is: lump in breast, distending pain of the breast, agitation are easily
Anger, insomnia and dreamful sleep, costa sternales distension, bitter taste etc..Cyclomastopathy can be divided into caused by hepatic stagnation qi stagnation and the big class of disharmony of Chong and Conception Channels type two.Stagnation of liver-QI gas
Stagnant type cyclomastopathy preceeded menorrhea or breast swell and pain menstrual period, disappear with susceptible to anger, the string that side or bilateral can be laid one's hand on and differ in size
Pearl nodule, lump mostly is Semen phaseoli radiati big step nodule, or becomes the most streak, and matter is tough the hardest, presses movable, does not glues with deep tissue
Even, border is situated between unclear, and menstrual cycle is not enough, more through amount, heating installation uncomfortable in chest, spirit depressing, susceptible to lose temper due to restlessness.Disharmony of Chong and Conception Channels type mammary gland increases
There is lump in lactogenesis room, and premenstrual or pain in menstrual period increases the weight of, and alleviates or disappear after row, prolongs after menstrual period are many, and dysmenorrhoea is the most acute, hypomenorrhea,
Body is tired unable, soreness of waist cold extremities, few abdomen fear of cold, with the passing of time loses the person of controlling, and minority can occur canceration.
The Chinese medicine composition prescription of the present invention is developed according to the mechanism of above-mentioned caused by hepatic stagnation qi stagnation cyclomastopathy disease, is adopted
Technical scheme as follows:
A kind of Chinese medicine composition treating cyclomastopathy, is made up of the raw material of following weight portion: Serissa foetida 15-30 part, Herba Patriniae
Grass 5-10 part, Semen Ricini 5-20 part, Sanguis Draxonis 3-11 part, Folium Symplocoris Caudatae 2-10 part, Herba seu Flos Convolvuli arvensis 2-10 part, Caulis Spatholobi 10-15 part, Rhizoma Curcumae
10-15 part, Semen Momordicae 10-15 part, Fructus anethi 7-11 part, soft Radix Bupleuri 9-21 part, Fructus Toosendan 10-30 part, Rhizoma Cyperi 15-20 part, elder brother
Cloth 10-15 part, Semen Vaccariae 1-5 part, Fructus Liquidambaris 1-5 part.
Preferably, the Chinese medicine composition of above-mentioned treatment cyclomastopathy is made up of the raw material of following weight portion: Serissa foetida 20-
25 parts, Herba Patriniae 6-9 part, Semen Ricini 10-15 part, Sanguis Draxonis 6-8 part, Folium Symplocoris Caudatae 5-7 part, Herba seu Flos Convolvuli arvensis 5-7 part, Caulis Spatholobi 11-14
Part, Rhizoma Curcumae 11-14 part, Semen Momordicae 11-14 part, Fructus anethi 8-10 part, soft Radix Bupleuri 12-18 part, Fructus Toosendan 15-25 part, Rhizoma Cyperi 16-
19 parts, Thallus Laminariae (Thallus Eckloniae) 11-14 part, Semen Vaccariae 2-4 part, Fructus Liquidambaris 2-4 part.
It is highly preferred that the Chinese medicine composition of above-mentioned treatment cyclomastopathy is made up of the raw material of following weight portion: Serissa foetida
23 parts, Herba Patriniae 8 parts, Semen Ricini 13 parts, Sanguis Draxonis 7 parts, Folium Symplocoris Caudatae 6 parts, Herba seu Flos Convolvuli arvensis 6 parts, Caulis Spatholobi 12 parts, Rhizoma Curcumae 12 parts, wood
Trionyx sinensis Wiegmann 12 parts, Fructus anethi 9 parts, soft Radix Bupleuri 15 parts, Fructus Toosendan 20 parts, Rhizoma Cyperi 18 parts, Thallus Laminariae (Thallus Eckloniae) 12 parts, Semen Vaccariae 3 parts, Fructus Liquidambaris
3 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment cyclomastopathy, comprises the following steps:
(1) Serissa foetida, Herba Patriniae, Semen Ricini addition are pulverized to bavin field formula pulverizer, cross 50-150 mesh, obtain medicated powder A；
(2) by Sanguis Draxonis, Folium Symplocoris Caudatae, Herba seu Flos Convolvuli arvensis, Caulis Spatholobi, Rhizoma Curcumae, Semen Momordicae, Fructus anethi, soft Radix Bupleuri, Fructus Toosendan, Rhizoma Cyperi, elder brother
Cloth, Semen Vaccariae, Fructus Liquidambaris boiling twice, merging filtrate, it is concentrated into relative density 1.10-1.20, adds ethanol and make to contain
Alcohol amount reaches 50%, stands 24 hours, takes supernatant, obtain water extract B；
(3) by water extract B decompression recycling ethanol to without alcohol taste, continue to be condensed into thick paste, obtain paste C.
(4) medicated powder A is added in paste C, mix homogeneously, the Chinese medicine composition of the cyclomastopathy that can obtain medical treatment.
In the present invention, further illustrating, in step (1), the granularity of described pulverizing is 50-150 mesh.
In the present invention, further illustrating, in step (2), described decoction twice, the 1st time 2 hours, the 2nd time 1.5 little
Time.
The Chinese medicine composition of above-mentioned treatment cyclomastopathy can make medicament according to conventional pharmaceutical methods, the dosage form of medicament
Can be capsule or oral liquid.
The instructions of taking of this Chinese medicine composition is: daily three times, and point morning, noon and afternoon take, and within one month, are a course for the treatment of,
Take 1-3 the course for the treatment of.
The concrete effect of raw material of Chinese medicine employed in the present invention is as follows:
Serissa foetida, Latin literary fame: Serissa serissoides (DC.) Druce, another name: broken leaf Ilicis Purpureae, Radix Serissae, jasmine,
Know tender tea leaves, Serissa foetida, know tender tea leaves for one, a jasmine.Light, micro-pungent, cool.Enter liver, spleen two warp.Soothing liver-QI for relieving depression, clearing away heat-damp and promoting diuresis, detumescence is pulled out
Poison, relieving cough and resolving phlegm.For acute hepatitis, lumbago, skelalgia of rheumatism, carbuncle malignant boil, venom, diarrhea due to hypofunction of the spleen, infantile malnutrition, leukorrheal diseases,
Corneal nebula, acute appendicitis, rabies.
Herba Patriniae, claims bitter benefit dish, herbaceous plant in the localities, is grown on the places such as patana more, cold in nature is slightly cold, acrid in the mouth
Bitter.When Chinese medicine infusion, there is strong foot odor taste, have the effects such as heat-clearing and toxic substances removing, removing blood stasis and expelling pus.Semen Ricini is euphorbia plant
The seed of Semen Ricini.This product has detumescence and drawing out poison, rushes down lower logical stagnant effect.For symptoms such as swollen ulcer drug, sore throat, constipation due to dry stooles.Castor
Fiber crops, the one of euphorbia plant, 1 year or herbaceos perennial.Herb is smooth, on by wax powder, generally in green, cinerous
Or aubergine；Stem circular hollow, has branch；Leaf alternate is relatively big, palmation；Panicle, unisexual flower is without petal, and female flower raw
On the top of inflorescence, pale red style, male flower is in the bottom of inflorescence, faint yellow；Capsule spinosity or stingless；Oval seed, plants
Skin is hard, glossy and have black, white, brown speckle.Happiness high temperature, is weak to frost, soda acid strong adaptability.For detumescence and drawing out poison；Lead under rushing down
Stagnant；Dredging collateral profit key.Main swollen ulcer drug；Scrofula；Acute mastitis；Sore throat；Mange tinea skin ulcer；Scald；Edema distension；Constipation due to dry stool；Mouth eye is askew
Tiltedly；Traumatic injury.
Sanguis Draxonis, Latin literary fame: Dragon ' s Blood, another name: Sanguis Draxonis, sea wax, dragon's blood, wood Sanguis Draxonis.Sweet in the mouth；Salty；
Property flat；Mild toxicity.GUIXIN warp；Liver Channel.Dissipating blood stasis analgesic therapy；Hemostasis；Promoting tissue regeneration and ulcer healing.Traumatic injury；Ecchymoma due to internal injury；Dysmenorrhea；Postpartum stagnation
Stomachache；Continuous bleeding due to traumatic injury；Scrofula；Ecthyma unhealed for long time and hemorrhoid.
Folium Symplocoris Caudatae, Latin literary fame: Symplocos sumuntia, another name: Liu Chunshu, Radix Polygalae Wattersii.Sour and astringent micro-sweet, nontoxic.
Attach to the lung and stomach meridians through.Heat-clearing and toxic substances removing；Astringing to arrest bleeding.Main chronic dysentery；Wind-fire acute conjunctivitis, tonsillitis；Otitis media；Hemoptysis；Have blood in stool, thrush
Skin ulcer
Herba seu Flos Convolvuli arvensis, Latin literary fame: Convolvulus arvensis L, another name: little Flos Calystegiae sepii, China's Flos Calystegiae sepii, arrow leaf Flos Calystegiae sepii, open country are led
Cattle, draw aster.Pungent；Temperature；Poisonous.Enter kidney channel.Dispelling wind for relieving itching；Pain relieving.Main air pain of dampness syndrome；Toothache；Neurodermatitis.
Caulis Spatholobi, for the another name of the various plants such as Schisandraceae, Sargentodoxaceae, Cuscutaceae, Papilionaceae.Bitter in the mouth is micro-
Sweet, warm in nature, return liver, the heart, kidney channel；Red complexion enters blood, and matter profit row dissipates；There is relaxing muscles and tendons to promote blood circulation, effect of nourishing blood for regulating menstruation；
Rhizoma Curcumae, Latin literary fame: Rhizoma Curcumae Aeruginosae, another name: Rhizoma Curcumae, radix zedoariae, smelly dung Rhizoma Zingiberis Recens.Pungent,
Hardship, temperature.Return liver, spleen channel.Removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.Expelling wind and removing dampness, reducing swelling and alleviating pain.For rheumatalgia, wind syndrome of head pain, breast is coerced
Bitterly, diarrhoea pain；Traumatic injury, swelling and pain due to blood stasis are controlled in external.
Semen Momordicae, formal name used at school: Momordica cochinchinensis (Lour.) Spreng, another name: vomiting nut, glutinous meal
Really, mouse draws Fructus Benincasae etc..Perennial herbaceous stem rattan wood, the tuberous root that tool expands.Stem has vertical rib；Tendril is sturdy, with leaf to life, single
One, not branch.Leaf alternate, circular to wealthy the most avette, long 7-14 centimetre, usual 3 shallow split or drastic crack, and sliver is slightly in avette or long ovum
Shape, full edge or have micro-tooth, base portion is the most heart-shaped, the anxious point of tip, above smooth, below the little mastoid process of close life, 3 go out palmate net arteries and veins；Petiole
Long 5-10 centimetre, the vertical rib of tool, at middle part or nearly blade, have 2-5 body of gland.Flower unisexuality, hermaphroditism.Often it is born in height above sea level 450-
Gully, border and the roadside of 1100 meters.Wild in hillside, the deep place of soil layer of border.Like warm and sufficient sunlight.Crossing cloudy ring
Undergrowth under border.It is distributed in the Yangtze river basin and areas to the south, South East Asia Mainland and Indian peninsula also to have.There are dispersing swelling and dissipating binds, toxic removing
Effect.Nature and flavor are bitter, micro-sweet, cool；Poisonous.Return liver, spleen, stomach warp.
Fructus anethi, Latin literary fame: Anethum graveolens, another name: time U.S.-China, Fructus anethi green pepper, Fructus Foeniculi, shrivelled kernel fennel
Perfume, cumin, kind scheme are strangled.Acrid in the mouth, temperature, nontoxic.Enter spleen, kidney channel.Warming the spleen whets the appetite；Cold expelling warms up liver；Regulating QI to relieve pain.In abdomen cold
Bitterly；Side of body rib distension；Vomiting lack of appetite；Colic of cold type.
Soft Radix Bupleuri, Latin literary fame: Bupleurum chinense DC, another name: ground is smoked, Asia puecon Hu, mountain dish, eat grass, faggot.
Bitter in the mouth, is slightly cold.Return Liver Channel, gallbladder meridian.Reconciling superficies and interior, soothing the liver, yang invigorating.Curing mainly alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache
Dizzy, malaria, lower profit proctoptosis, menoxenia, uterine prolapse.
Fructus Toosendan, Latin literary fame: MeliatoosendanSieb, another name: chinaberry reality, Fructus Toosendan, core Fructus Jujubae, Fructus Toosendan, chinaberry,
The stone Fructus Evodiae, Fructus Toosendan.Hardship, cold；Slightly poisonous.Return liver, small intestinal, bladder warp.Soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, gastral cavity abdominal distention
Bitterly, colic, abdominal pain due to worm stagnation.
Rhizoma Cyperi, Latin literary fame: Cyperus rotundus, another name: dried tuber, big Rhizoma Cyperi, soil perfume, water perfume (or spice) rib, DICAO.Sweet in the mouth,
It is slightly cold, nontoxic.Enter lung, liver, spleen, stomach four warp.Regulate the flow of vital energy resolving depression, regulating menstruation, pain relieving.Curing mainly incoordination between the liver and stomach, depression of QI, chest and abdomen are swollen
Full, menoxenia, the disease such as dysmenorrhea.
Thallus Laminariae (Thallus Eckloniae) gas raw meat, salty in the mouth.Return liver, stomach, kidney channel.There are hard masses softening and resolving, expectorant, the function of diuretic.Thallus Laminariae (Thallus Eckloniae) (Ecklonia
Kurome) " black dish ", " goose palm dish ", " five palm dishes " etc. it are also known as.Phaeophyceae, Alariaceae.Sporinite is large-scale, brown, keratin, high
30-100cm, leaflet sheet, shank, holdfast, holdfast rhizoid shape.Rhizoid two V shape branch, shank cylindrical shape, nearly blade part is gradually
Flat, blade both sides pinniform or coverts shape branch, middle part is the thickest, intercalary growth, long 1-12cm, thick 3-7mm, rough sawn tingia edge.
Zoospore is born in blade two sides.There is the significantly metagenesis such as the most not.It is grown in ocean, temperate zone.Zhejiang Province, China, ALONG COASTAL FUJIAN
There is distribution.For phlegm retention edema.Hard masses softening and resolving, expectorant, diuretic.Goiter, scrofula, painful and swollen testis, phlegm retention edema.
Semen Vaccariae, bitter, flat.Return liver, stomach warp.For pinkwort Vaccaria segetalis Vaccaria segetalis (Neck.)
The dry mature seed of Garcke.Summer, fruit became heat, peel to tap plant when not yet ftractureing, and dries, lays seed, removes miscellaneous
Matter, then dry.In addition to south China, there is distribution in district in all parts of the country.Having promoting blood circulation to restore menstrual flow, stimulating milk secretion is subsided a swelling, effect of inducing diuresis for treating stranguria syndrome.With
In amenorrhea, dysmenorrhea, agalactia, acute mastitis swells and ache, the puckery pain of stranguria.
Fructus Liquidambaris, for the drying and ripening fruit of Hamamelidaceae Plants Chinese sweet gum Liquidambar formosana Hance
Sequence.Winter gathers after fruit maturation, removes impurity, is dried.Bitter in the mouth, property is put down.Liver, kidney channel.There are dispelling, collateral-activating, diuretic, stimulate the menstrual flow
Effect.
In sum, owing to have employed technique scheme, the invention has the beneficial effects as follows:
The prescription of the present invention, scientific and reasonable compatibility, be for treatment caused by hepatic stagnation qi stagnation cyclomastopathy and develop, side in Serissa foetida,
Rhizoma Cyperi has soothing liver-QI for relieving depression, effect of pain relieving；Herba Patriniae, Sanguis Draxonis have powder detoxifcation, the effect of removing heat-phlegm；Herba seu Flos Convolvuli arvensis, Caulis Spatholobi,
Semen Ricini, Rhizoma Curcumae, Semen Momordicae, Fructus anethi, Fructus Toosendan have liver-smoothing, qi-regulating, promoting blood circulation to remove blood stasis, effect of dispersing cold for relieving pain；Folium Symplocoris Caudatae, soft
Radix Bupleuri and Fructus Liquidambaris have heat-clearing and toxic substances removing, effect of reconciling superficies and interior；Thallus Laminariae (Thallus Eckloniae), Semen Vaccariae have clearing away heat and promoting diuresis, the effect invigorated blood circulation.All medicines
Share, play altogether resolving depression eliminating stagnation, regulating blood circulation, the clear core of blood stasis dispelling principle to treat cyclomastopathy, there is instant effect, good effect, nothing
The advantage of toxic and side effects.Achieve obvious clinical effectiveness by clinic application, be used for treating caused by hepatic stagnation qi stagnation cyclomastopathy, always have
Efficiency reaches 93.3%, without obvious toxic-side effects.
[detailed description of the invention]
The invention provides a kind of Chinese medicine composition treating cyclomastopathy, be made up of the raw material of following weight portion: Serissa foetida 15-
30 parts, Herba Patriniae 5-10 part, Semen Ricini 5-20 part, Sanguis Draxonis 3-11 part, Folium Symplocoris Caudatae 2-10 part, Herba seu Flos Convolvuli arvensis 2-10 part, Caulis Spatholobi 10-
15 parts, Rhizoma Curcumae 10-15 part, Semen Momordicae 10-15 part, Fructus anethi 7-11 part, soft Radix Bupleuri 9-21 part, Fructus Toosendan 10-30 part, Rhizoma Cyperi
15-20 part, Thallus Laminariae (Thallus Eckloniae) 10-15 part, Semen Vaccariae 1-5 part, Fructus Liquidambaris 1-5 part.Kinds of traditional Chinese medicines complements each other, play altogether resolving depression eliminating stagnation,
The merit of the clear core of regulating blood circulation, blood stasis dispelling, and then the effective state of an illness controlling caused by hepatic stagnation qi stagnation cyclomastopathy.Below by way of being embodied as
The invention will be further described for example.
Embodiment 1
A kind of Chinese medicine composition treating cyclomastopathy, is made up of the raw material of following weight portion: Serissa foetida 15g, Herba Patriniae 5g,
Semen Ricini 5g, Sanguis Draxonis 3g, Folium Symplocoris Caudatae 2g, Herba seu Flos Convolvuli arvensis 2g, Caulis Spatholobi 10g, Rhizoma Curcumae 10g, Semen Momordicae 10g, Fructus anethi 7g, soft Radix Bupleuri
9g, Fructus Toosendan 10g, Rhizoma Cyperi 15g, Thallus Laminariae (Thallus Eckloniae) 10g, Semen Vaccariae 1g, Fructus Liquidambaris 1g.
Following method is used to prepare this Chinese medicine composition:
(1) Serissa foetida, Herba Patriniae, Semen Ricini addition are pulverized to bavin field formula pulverizer, cross 100 mesh, obtain medicated powder A；
(2) by Sanguis Draxonis, Folium Symplocoris Caudatae, Herba seu Flos Convolvuli arvensis, Caulis Spatholobi, Rhizoma Curcumae, Semen Momordicae, Fructus anethi, soft Radix Bupleuri, Fructus Toosendan, Rhizoma Cyperi, elder brother
Cloth, Semen Vaccariae, Fructus Liquidambaris boiling twice, merging filtrate, it is concentrated into relative density 1.15, adds ethanol and make alcohol content reach
50%, stand 24 hours, take supernatant, obtain water extract B；
(3) by water extract B decompression recycling ethanol to without alcohol taste, continue to be condensed into thick paste, obtain paste C.
(4) medicated powder A is added in paste C, mix homogeneously, the Chinese medicine composition of the cyclomastopathy that can obtain medical treatment.
Embodiment 2
A kind of Chinese medicine composition treating cyclomastopathy, is made up of the raw material of following weight portion: Serissa foetida 20g, Herba Patriniae 6g,
Semen Ricini 10g, Sanguis Draxonis 6g, Folium Symplocoris Caudatae 5g, Herba seu Flos Convolvuli arvensis 5g, Caulis Spatholobi 11g, Rhizoma Curcumae 11g, Semen Momordicae 11g, Fructus anethi 8g, soft bavin
12g, Fructus Toosendan 15g, Rhizoma Cyperi 16g, Thallus Laminariae (Thallus Eckloniae) 11g, Semen Vaccariae 2g, Fructus Liquidambaris 2g recklessly.
Following method is used to prepare this Chinese medicine composition:
(1) Serissa foetida, Herba Patriniae, Semen Ricini addition are pulverized to bavin field formula pulverizer, cross 150 mesh, obtain medicated powder A；
(2) by Sanguis Draxonis, Folium Symplocoris Caudatae, Herba seu Flos Convolvuli arvensis, Caulis Spatholobi, Rhizoma Curcumae, Semen Momordicae, Fructus anethi, soft Radix Bupleuri, Fructus Toosendan, Rhizoma Cyperi, elder brother
Cloth, Semen Vaccariae, Fructus Liquidambaris boiling twice, merging filtrate, it is concentrated into relative density 1.20, adds ethanol and make alcohol content reach
50%, stand 24 hours, take supernatant, obtain water extract B；
(3) by water extract B decompression recycling ethanol to without alcohol taste, continue to be condensed into thick paste, obtain paste C.
(4) medicated powder A is added in paste C, mix homogeneously, the Chinese medicine composition of the cyclomastopathy that can obtain medical treatment.
Embodiment 3
A kind of Chinese medicine composition treating cyclomastopathy, is made up of the raw material of following weight portion: Serissa foetida 23g, Herba Patriniae 8g,
Semen Ricini 13g, Sanguis Draxonis 7g, Folium Symplocoris Caudatae 6g, Herba seu Flos Convolvuli arvensis 6g, Caulis Spatholobi 12g, Rhizoma Curcumae 12g, Semen Momordicae 12g, Fructus anethi 9g, soft bavin
15g, Fructus Toosendan 20g, Rhizoma Cyperi 18g, Thallus Laminariae (Thallus Eckloniae) 12g, Semen Vaccariae 3g, Fructus Liquidambaris 3g recklessly.
Following method is used to prepare this Chinese medicine composition:
(1) Serissa foetida, Herba Patriniae, Semen Ricini addition are pulverized to bavin field formula pulverizer, cross 50 mesh, obtain medicated powder A；
(2) by Sanguis Draxonis, Folium Symplocoris Caudatae, Herba seu Flos Convolvuli arvensis, Caulis Spatholobi, Rhizoma Curcumae, Semen Momordicae, Fructus anethi, soft Radix Bupleuri, Fructus Toosendan, Rhizoma Cyperi, elder brother
Cloth, Semen Vaccariae, Fructus Liquidambaris boiling twice, merging filtrate, it is concentrated into relative density 1.10, adds ethanol and make alcohol content reach
50%, stand 24 hours, take supernatant, obtain water extract B；
(3) by water extract B decompression recycling ethanol to without alcohol taste, continue to be condensed into thick paste, obtain paste C.
(4) medicated powder A is added in paste C, mix homogeneously, the Chinese medicine composition of the cyclomastopathy that can obtain medical treatment.
Embodiment 4
A kind of Chinese medicine composition treating cyclomastopathy, is made up of the raw material of following weight portion: Serissa foetida 30g, Herba Patriniae
10g, Semen Ricini 20g, Sanguis Draxonis 11g, Folium Symplocoris Caudatae 10g, Herba seu Flos Convolvuli arvensis 10g, Caulis Spatholobi 15g, Rhizoma Curcumae 15g, Semen Momordicae 15g, Fructus anethi
11g, soft Radix Bupleuri 21g, Fructus Toosendan 30g, Rhizoma Cyperi 20g, Thallus Laminariae (Thallus Eckloniae) 15g, Semen Vaccariae 5g, Fructus Liquidambaris 5g.
The method identical with embodiment 3 is used to prepare this Chinese medicine composition.
Embodiment 5
A kind of Chinese medicine composition treating cyclomastopathy, is made up of the raw material of following weight portion: Serissa foetida 25g, Herba Patriniae 9g,
Semen Ricini 15g, Sanguis Draxonis 8g, Folium Symplocoris Caudatae 7g, Herba seu Flos Convolvuli arvensis 7g, Caulis Spatholobi 14g, Rhizoma Curcumae 14g, Semen Momordicae 14g, Fructus anethi 10g, soft bavin
18g, Fructus Toosendan 25g, Rhizoma Cyperi 19g, Thallus Laminariae (Thallus Eckloniae) 14g, Semen Vaccariae 4g, Fructus Liquidambaris 4g recklessly.
The method identical with embodiment 3 is used to prepare this Chinese medicine composition.
In order to observe the clinical efficacy of present composition treatment cyclomastopathy, the present invention is carried out concept clinical sight
Examine, now clinical test results be reported as follows:
(1) object of observation: during in January, 2016-June, uses the Chinese medicine composition of the present invention to treat 60 example patients altogether, unilateral
Cyclomastopathy 32 example, bilateral breast falls ill 28 examples, age 25-40 year, 30 years old mean age, the course of disease 2 months-2 years, average 13
Month.
(2) diagnostic criteria: lump in breast, distending pain of the breast, irritable, insomnia and dreamful sleep, costa sternales distension, bitter taste etc..
(3) Therapeutic Method: arbitrary Chinese medicine composition made in oral embodiment of the present invention 1-5, daily three times, point
Morning, noon and afternoon take, and within one month, are a course for the treatment of, take 1-3 the course for the treatment of, follow up a case by regular visits to after 3 months, add up recurrence.
(4) the standard of curative effect evaluation:
1. recovery from illness: distending pain of the breast and lump disappear, takes the photograph sheet inspection in conjunction with breast molybdenum target and confirms that cyclomastopathy sign disappears.Drug withdrawal
Within latter 3 months, do not recur.
The most effective: in breast, lump disappears, quality deliquescing, pain disappears, and ultrasonic examination prompting shadow disappears, near infrared ray
Check as normal breast image.
The most effective: distending pain of the breast alleviates, physical palpation mass reduction 2/3, breast molybdenum target is taken the photograph sheet inspection and is confirmed cyclomastopathy
Take a turn for the better, be substantially consistent with clinical symptoms and palpation.
The most invalid: distending pain of the breast is not improved compared with before treatment with lump, and breast molybdenum target take the photograph sheet inspection confirm.
(5) therapeutic outcome: in 60 example cases, through 1-3 course of therapy, wherein cures 29 examples, effective 15 examples, and effective 12
Example, invalid 4 examples, total effective rate 93.3%, the course for the treatment of is the shortest 30 days, the longest 150 days, follows up a case by regular visits to 1 year have no recurrence.
Model case:
Cai, 38 years old, female, the course of disease 1 year, breast had that lump, lump be relatively big, irritability, insomnia and dreamful sleep, distending pain of the breast, takes enforcement
The Chinese medicine composition of example 1 takes effect January, within 1 year, cures.
Hu, 34 years old, female, the course of disease 3 months, lump in breast, distending pain of the breast, insomnia and dreamful sleep, costa sternales distension, bitter taste, take
The Chinese medicine composition of embodiment 1 takes effect January, and 3 courses for the treatment of cure.
Described above is the detailed description for the preferable possible embodiments of the present invention, but embodiment is not limited to this
Bright patent claim, the equal change completed under the technical spirit suggested by all present invention or modification change, all should belong to
In the contained the scope of the claims of the present invention.
Claims (6)
1. the Chinese medicine composition treating cyclomastopathy, it is characterised in that: it is made up of the raw material of following weight portion: Serissa foetida
15-30 part, Herba Patriniae 5-10 part, Semen Ricini 5-20 part, Sanguis Draxonis 3-11 part, Folium Symplocoris Caudatae 2-10 part, Herba seu Flos Convolvuli arvensis 2-10 part, Caulis Spatholobi
10-15 part, Rhizoma Curcumae 10-15 part, Semen Momordicae 10-15 part, Fructus anethi 7-11 part, soft Radix Bupleuri 9-21 part, Fructus Toosendan 10-30 part, perfume (or spice)
Attached 15-20 part, Thallus Laminariae (Thallus Eckloniae) 10-15 part, Semen Vaccariae 1-5 part, Fructus Liquidambaris 1-5 part.
A kind of Chinese medicine composition treating cyclomastopathy the most according to claim 1, it is characterised in that: by following weight portion
Raw material make: Serissa foetida 20-25 part, Herba Patriniae 6-9 part, Semen Ricini 10-15 part, Sanguis Draxonis 6-8 part, Folium Symplocoris Caudatae 5-7 part, Tian Xuan
Flower 5-7 part, Caulis Spatholobi 11-14 part, Rhizoma Curcumae 11-14 part, Semen Momordicae 11-14 part, Fructus anethi 8-10 part, soft Radix Bupleuri 12-18 part, river
Chinaberry 15-25 part, Rhizoma Cyperi 16-19 part, Thallus Laminariae (Thallus Eckloniae) 11-14 part, Semen Vaccariae 2-4 part, Fructus Liquidambaris 2-4 part.
A kind of Chinese medicine composition treating cyclomastopathy the most according to claim 1, it is characterised in that: by following weight portion
Raw material make: Serissa foetida 23 parts, Herba Patriniae 8 parts, Semen Ricini 13 parts, Sanguis Draxonis 7 parts, Folium Symplocoris Caudatae 6 parts, Herba seu Flos Convolvuli arvensis 6 parts, Caulis Spatholobi
12 parts, Rhizoma Curcumae 12 parts, Semen Momordicae 12 parts, Fructus anethi 9 parts, soft Radix Bupleuri 15 parts, Fructus Toosendan 20 parts, Rhizoma Cyperi 18 parts, Thallus Laminariae (Thallus Eckloniae) 12 parts, king
Do not stay row 3 parts, Fructus Liquidambaris 3 parts.
4., according to the preparation method of a kind of Chinese medicine composition treating cyclomastopathy described in claim 1,2 or 3, its feature exists
In: comprise the following steps:
(1) Serissa foetida, Herba Patriniae, Semen Ricini addition are pulverized to bavin field formula pulverizer, cross 50-150 mesh, obtain medicated powder A；
(2) by Sanguis Draxonis, Folium Symplocoris Caudatae, Herba seu Flos Convolvuli arvensis, Caulis Spatholobi, Rhizoma Curcumae, Semen Momordicae, Fructus anethi, soft Radix Bupleuri, Fructus Toosendan, Rhizoma Cyperi, elder brother
Cloth, Semen Vaccariae, Fructus Liquidambaris boiling twice, merging filtrate, it is concentrated into relative density 1.10-1.20, adds ethanol and make to contain
Alcohol amount reaches 50%, stands 24 hours, takes supernatant, obtain water extract B；
(3) by water extract B decompression recycling ethanol to without alcohol taste, continue to be condensed into thick paste, obtain paste C；
(4) medicated powder A is added in paste C, mix homogeneously, the Chinese medicine composition of the cyclomastopathy that can obtain medical treatment.
The preparation method of a kind of Chinese medicine composition treating cyclomastopathy the most according to claim 4, it is characterised in that:
In step (1), the granularity of described pulverizing is 50-150 mesh.
The preparation method of a kind of Chinese medicine composition treating cyclomastopathy the most according to claim 4, it is characterised in that:
In step (2), described decoction twice, the 1st time 2 hours, the 2nd time 1.5 hours.
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| CN105311581A (en) * | 2015-12-02 | 2016-02-10 | 青岛市中心医院 | Traditional Chinese medicine composition for preventing and treating hyperplasia of mammary glands and preparation method thereof |
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| CN105311581A (en) * | 2015-12-02 | 2016-02-10 | 青岛市中心医院 | Traditional Chinese medicine composition for preventing and treating hyperplasia of mammary glands and preparation method thereof |
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