CN106237132A - A kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces and preparation method thereof - Google Patents

A kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces and preparation method thereof Download PDF

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Publication number
CN106237132A
CN106237132A CN201610642869.5A CN201610642869A CN106237132A CN 106237132 A CN106237132 A CN 106237132A CN 201610642869 A CN201610642869 A CN 201610642869A CN 106237132 A CN106237132 A CN 106237132A
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fructus phyllanthi
antiinflammatory
decoction pieces
stomach invigorating
digestion promoting
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梁勇
张涛
张�廷
岳勇
闫肖肖
杜诗荣
刘召
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Anhui Xinsheng Traditional Chinese Medicine Co Ltd
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Anhui Xinsheng Traditional Chinese Medicine Co Ltd
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

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Abstract

The invention discloses a kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces and preparation method thereof, be made up of following raw materials in part by weight: Fructus Phyllanthi 50 60, apple vinegar 30 35, Rhizoma Dioscoreae powder 200 230, Radix Et Rhizoma Fagopyri Tatarici 78, Mel 30 35, puffed oat powder 25 30, Semen Armeniacae Amarum 15 18, Semen Phaseoli 15 18, Endothelium Corneum Gigeriae Galli 10 12, yeast mixture 10 12, the Rhizoma Atractylodis Macrocephalae 10 12, Cortex Moutan 10 12.A kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces of the present invention, is different from traditional single decoction pieces, is compounded with multiple beneficial composition so that it is complement each other, have the effects such as antiinflammatory, stomach invigorating, digestion promoting, dissipating blood stasis heat clearing away.

Description

A kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces and preparation method thereof
Technical field
The present invention relates to prepared slices of Chinese crude drugs technical field, particularly relate to a kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces and Its preparation method.
Background technology
The prepared slices of Chinese crude drugs are under guidance of traditional Chinese medicine theory, according to determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs principle and the needs of formulation dispensing, to Chinese medicine The finished product of material Processing methods is tcm clinical practice medication, play dialectical plus-minus, embody the basis of personalized medicine principle.Chinese medicine is drunk Sheet is one of big pillar of Chinese herbal medicine industry three, the important component part of Ye Shi China traditional medicine, diseases prevention, cure the disease in play Important effect.Therefore the quality of The Quality of Sliced Herbal Medicine is by directly influencing the effect of tcm clinical practice treatment, has influence on the people Masses' life and health and the safety of medication.
Chinese medicine wall cell disruption powder body and Chinese medicine wall cell disruption decoction pieces are the modern developments of Chinese medicinal powder application, the utilization rate of its material base More traditional decoction pieces has a more substantial increase.Research work expands around association area and studies more than the tackling key problem of 300 sub-problems. The Chinese crude drug overwhelming majority derives from natural plant, derives from animal, mineral and artifact on a small quantity.And plant medicine material Being respectively provided with cell wall structure, use traditional decoction extracting mode, cell wall can stop intracellular active substance to a great extent Dissolution, causes active ingredients from traditional Chinese medicinal utilization rate low, serious waste of resources.Chinese medicine wall cell disruption decoction pieces is broken by modern crushing technology Cell wall, allows the material in cell wall be prone to dissolution and mix homogeneously, can be effectively improved Chinese crude drug because of its position and tissue etc. no The problem of the material base inhomogeneities caused together, improves leaching rate and the utilization rate of effective ingredient in medical material, also achieves Chinese medicine without long-time high temperature decoct extract process, and apply convenient.And in traditional Chinese herbs broken wall link, rational breaking cell wall Diameter of particle is that it is crucial.The diameter of general cell is all about 10-100 μm.After being processed by cellular level pulverizing, in inciting somebody to action Pulverizing medicinal materials is to 300 mesh (sieve aperture internal diameter is 47 μm), and cell-wall breaking ratio can reach 86.5%.The 300 above Chinese traditional powder of mesh, 98% is micro- Powder can only see cell debris.The medium particle diameter that general 300 mesh Chinese medicinal powder microscope inspections measure is 4-10 μm.This grain The ultrafine Chinese herb in footpath can make its components utilising rate improve to 60-90%.From economic and technical comprehensive examination and evaluation, Chinese medicine wall cell disruption decoction pieces selects Selecting micronizing and be machined to D90 < 45 μm, < powder body of 45 μm (more than 300 mesh) breaks the diameter of particle of i.e. more than 90% as Chinese medicine The standard of wall powder body.This breaking cell wall processes and belongs to fine physical refining process, intracellular material composition is not caused matter Change.The wall breaking pulverization technology of Chinese medicine is the most mature in the industry two classes: one has rigid solid medium to participate in, by hitting Hit, shear, the conventional size reduction principle such as friction breaks the technology of cell wall;Two do not have rigid solid medium to participate in, and utilize strong Strong air-flow breaks the technology of cell wall by Chinese traditional powder self high frequency, fast ram.The pulverizing skill that rigid solid medium participates in The feature of art is: medium, owing to being clashed into and rubbing, easy to wear comes off, and pollutes medical material;When medium high-speed impact, shearing medical material , make medical material produce higher temperature, be unfavorable for the protection of heat-sensitive ingredients;But the subject range width that this technology is to medical material, to material Physical property requires low.The feature of airflow pulverization is: do not have rigid solid medium contacting material, the suction of air-flow high speed pay-out The heat production of heat and material impacting is offset, and material does not heats up at crushing process, so that heat-sensitive ingredients is effectively protected;But air-flow The physical property of material is required higher by crushing technology, and subject range is narrower.For ensureing to greatest extent to process through cell wall breaking Chinese traditional powder pollution-free, do not heat up, Chinese medicine wall cell disruption decoction pieces select airflow pulverization realize breaking cell wall.Chinese medicine wall cell disruption decoction pieces After wall breaking pulverization processes, define the specific surface area moisture absorption big, easy, oxidizable and the powder body of poor fluidity, extremely unstable and difficulty To meet the industrialized production requirement to its mobility.Therefore, allow Chinese medicine wall cell disruption powder body after breaking cellular wall again molding with reduce ratio Surface area, improves the key problem in technology that stability is exactly its industrialization.
Summary of the invention
The object of the invention is contemplated to make up the defect of prior art, it is provided that a kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi Decoction pieces.
The present invention is achieved by the following technical solutions:
A kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces, is made up of following raw materials in part by weight:
Fructus Phyllanthi 50-60, apple vinegar 30-35, Rhizoma Dioscoreae powder 200-230, Radix Et Rhizoma Fagopyri Tatarici 7-8, Mel 30-35, puffed oat powder 25-30, Semen Armeniacae Amarum 15-18, Semen Phaseoli 15-18, Endothelium Corneum Gigeriae Galli 10-12, yeast mixture 10-12, Rhizoma Atractylodis Macrocephalae 10-12, Cortex Moutan 10-12.
Described a kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces, is made up of the following step:
1), Radix Et Rhizoma Fagopyri Tatarici, Endothelium Corneum Gigeriae Galli, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, apple vinegar being added in steamer, decoct altogether twice, the decoction liquor after filter is taken out, Load in clean container;
2), by Fructus Phyllanthi, Semen Armeniacae Amarum, Semen Phaseoli mix homogeneously in rustless steel container, and put into pulverizer, be ground into thin Cross 100-120 mesh sieve after powder, recycle airflow pulverization, it is carried out fining-off so that it is reach 300-350 mesh;
3), step 2 gained mixture is added in mixer with Rhizoma Dioscoreae powder, puffed oat powder, yeast mixture, after being sufficiently mixed, The mixing decoction liquor adding step 1 gained is stirred soft material processed, stirs 15-20 minute;
4), by step 3 gains take out put stainless steel disc in pile up in heaps, surface pat smooth, cover tightly with non-woven fabrics, in temperature For 30-35 DEG C, humidity 70-80%, ferment, after 3-4 days, treat that white mould clothing is uniformly born on stockpile surface, and crackle occurs, break Cut-off mask when having cellular, fermented standby;
5) mixture, by step 4 fermented is whole broken, mixes with Mel, puts in molding device, by molding device standard operating procedure Operate, be cut into the cubed pieces of the long 1.0-1.5cm of rib;
6), by step 5 gained cubed pieces, load in a clean rustless steel drip pan, pave, must not extrude, put into hot air circulation Drying in baking oven, operate according to heated-air circulation oven standard operating procedure, baking temperature is 70-80 DEG C, when being dried Between be 4-5 hour, water content control is at 7-12%, after drying, takes out, cools, loads in clean container, use outer, interior two layers multiple Closing the form of packaging, internal layer packaging is non-toxic polyethylene bag, and outer packaging is corrugated case, kept dry.
The invention have the advantage that
1, a kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces of the present invention, carries out powder by airflow pulverization to material Broken, there is no rigid solid medium contacting material, the heat absorption of air-flow high speed pay-out and the heat production of material impacting are offset, and material is being pulverized Process does not heats up, so that heat-sensitive ingredients is effectively protected.
2, the present invention utilizes the adhesion characteristics of Mel, and the material of powder is reinvented molding, makes the decoction pieces surface after molding thin Close smooth, it is difficult to loose, and improves palatability, abundant nutrition by Mel.
3, a kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces of the present invention, is different from traditional single decoction pieces, is compounded with Multiple beneficial composition so that it is complement each other, has the effects such as antiinflammatory, stomach invigorating, digestion promoting, dissipating blood stasis heat clearing away.
Detailed description of the invention
A kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces, is made up of following raw materials in part by weight:
Fructus Phyllanthi 50, apple vinegar 30, Rhizoma Dioscoreae powder 200, Radix Et Rhizoma Fagopyri Tatarici 7, Mel 30, puffed oat powder 25, Semen Armeniacae Amarum 15, Semen Phaseoli 15, Endothelium Corneum Gigeriae Galli 10, yeast mixture 10, the Rhizoma Atractylodis Macrocephalae 10, Cortex Moutan 10.
Described a kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces, is made up of the following step:
1), Radix Et Rhizoma Fagopyri Tatarici, Endothelium Corneum Gigeriae Galli, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, apple vinegar being added in steamer, decoct altogether twice, the decoction liquor after filter is taken out, Load in clean container;
2), by Fructus Phyllanthi, Semen Armeniacae Amarum, Semen Phaseoli mix homogeneously in rustless steel container, and put into pulverizer, be ground into thin Cross 100 mesh sieves after powder, recycle airflow pulverization, it is carried out fining-off so that it is reach 320 mesh;
3), step 2 gained mixture is added in mixer with Rhizoma Dioscoreae powder, puffed oat powder, yeast mixture, after being sufficiently mixed, The mixing decoction liquor adding step 1 gained is stirred soft material processed, stirs 15 minutes;
4), by step 3 gains take out put stainless steel disc in pile up in heaps, surface pat smooth, cover tightly with non-woven fabrics, in temperature It is 30 DEG C, humidity 70%, ferments, after 3 days, treat that white mould clothing is uniformly born on stockpile surface, and crackle occurs, break section tool into two with one's hands When having cellular, ferment standby;
5) mixture, by step 4 fermented is whole broken, mixes with Mel, puts in molding device, by molding device standard operating procedure Operate, be cut into the cubed pieces of the long 1.0cm of rib;
6), by step 5 gained cubed pieces, load in a clean rustless steel drip pan, pave, must not extrude, put into hot air circulation Drying in baking oven, operate according to heated-air circulation oven standard operating procedure, baking temperature is 70 DEG C, and drying time is 4 hours, water content control was 7%, after drying, takes out, cools, and loaded in clean container, used outer, interior two layers of composite packaging Form, internal layer packaging is non-toxic polyethylene bag, and outer packaging is corrugated case, kept dry.

Claims (2)

1. antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces, it is characterised in that be made up of following raw materials in part by weight:
Fructus Phyllanthi 50-60, apple vinegar 30-35, Rhizoma Dioscoreae powder 200-230, Radix Et Rhizoma Fagopyri Tatarici 7-8, Mel 30-35, puffed oat powder 25-30, Semen Armeniacae Amarum 15-18, Semen Phaseoli 15-18, Endothelium Corneum Gigeriae Galli 10-12, yeast mixture 10-12, Rhizoma Atractylodis Macrocephalae 10-12, Cortex Moutan 10-12.
A kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces the most according to claim 1, it is characterised in that be by following Step is made:
1), Radix Et Rhizoma Fagopyri Tatarici, Endothelium Corneum Gigeriae Galli, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, apple vinegar being added in steamer, decoct altogether twice, the decoction liquor after filter is taken out, Load in clean container;
2), by Fructus Phyllanthi, Semen Armeniacae Amarum, Semen Phaseoli mix homogeneously in rustless steel container, and put into pulverizer, be ground into thin Cross 100-120 mesh sieve after powder, recycle airflow pulverization, it is carried out fining-off so that it is reach 300-350 mesh;
3), step 2 gained mixture is added in mixer with Rhizoma Dioscoreae powder, puffed oat powder, yeast mixture, after being sufficiently mixed, The mixing decoction liquor adding step 1 gained is stirred soft material processed, stirs 15-20 minute;
4), by step 3 gains take out put stainless steel disc in pile up in heaps, surface pat smooth, cover tightly with non-woven fabrics, in temperature For 30-35 DEG C, humidity 70-80%, ferment, after 3-4 days, treat that white mould clothing is uniformly born on stockpile surface, and crackle occurs, break Cut-off mask when having cellular, fermented standby;
5) mixture, by step 4 fermented is whole broken, mixes with Mel, puts in molding device, by molding device standard operating procedure Operate, be cut into the cubed pieces of the long 1.0-1.5cm of rib;
6), by step 5 gained cubed pieces, load in a clean rustless steel drip pan, pave, must not extrude, put into hot air circulation Drying in baking oven, operate according to heated-air circulation oven standard operating procedure, baking temperature is 70-80 DEG C, when being dried Between be 4-5 hour, water content control is at 7-12%, after drying, takes out, cools, loads in clean container, use outer, interior two layers multiple Closing the form of packaging, internal layer packaging is non-toxic polyethylene bag, and outer packaging is corrugated case, kept dry.
CN201610642869.5A 2016-08-09 2016-08-09 A kind of antiinflammatory stomach invigorating digestion promoting micro-ferment Fructus Phyllanthi decoction pieces and preparation method thereof Pending CN106237132A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104324103A (en) * 2014-10-17 2015-02-04 磐安县道地磐药中药研究所 Medicated leaven pure powder superfine decoction piece and preparation method thereof
CN104673570A (en) * 2015-02-05 2015-06-03 栗阳 Health wine
CN105124345A (en) * 2015-09-28 2015-12-09 哈密阿萨尔生物科技有限公司 Emblic leafflower fruit stomach-invigorating honey ointment

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104324103A (en) * 2014-10-17 2015-02-04 磐安县道地磐药中药研究所 Medicated leaven pure powder superfine decoction piece and preparation method thereof
CN104673570A (en) * 2015-02-05 2015-06-03 栗阳 Health wine
CN105124345A (en) * 2015-09-28 2015-12-09 哈密阿萨尔生物科技有限公司 Emblic leafflower fruit stomach-invigorating honey ointment

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Application publication date: 20161221