CN106235331A - A kind of extracting method of Arillus Longan - Google Patents
A kind of extracting method of Arillus Longan Download PDFInfo
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- CN106235331A CN106235331A CN201610622512.0A CN201610622512A CN106235331A CN 106235331 A CN106235331 A CN 106235331A CN 201610622512 A CN201610622512 A CN 201610622512A CN 106235331 A CN106235331 A CN 106235331A
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- Prior art keywords
- arillus longan
- casing
- silica gel
- tank body
- plate
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- 240000001008 Dimocarpus longan Species 0.000 title claims abstract description 74
- 235000000235 Euphoria longan Nutrition 0.000 title claims abstract description 74
- 238000000034 method Methods 0.000 title claims abstract description 56
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 33
- 239000000741 silica gel Substances 0.000 claims abstract description 31
- 229910002027 silica gel Inorganic materials 0.000 claims abstract description 31
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 27
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 claims abstract description 23
- 235000013361 beverage Nutrition 0.000 claims abstract description 19
- 239000007788 liquid Substances 0.000 claims abstract description 17
- 239000012141 concentrate Substances 0.000 claims abstract description 15
- 239000008187 granular material Substances 0.000 claims abstract description 15
- 238000003756 stirring Methods 0.000 claims abstract description 13
- NQGCBDWQKDAGTK-RYZVSIALSA-N Agrimophol Chemical compound CC1=C(OC)C(C(=O)CCC)=C(O)C(C[C@]2(C)C(C(C(=O)[C@H](C)CC)=C(O)C(C)=C2O)=O)=C1O NQGCBDWQKDAGTK-RYZVSIALSA-N 0.000 claims abstract description 12
- NQGCBDWQKDAGTK-QDXKXIGTSA-N Agrimophol Natural products O=C(CCC)c1c(OC)c(C)c(O)c(C[C@]2(C)C(=O)C(C(=O)[C@H](CC)C)=C(O)C(C)=C2O)c1O NQGCBDWQKDAGTK-QDXKXIGTSA-N 0.000 claims abstract description 12
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 claims abstract description 11
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 claims abstract description 11
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229960001285 quercetin Drugs 0.000 claims abstract description 11
- 235000005875 quercetin Nutrition 0.000 claims abstract description 11
- 239000012535 impurity Substances 0.000 claims abstract description 8
- 239000000706 filtrate Substances 0.000 claims abstract description 7
- 239000012567 medical material Substances 0.000 claims abstract description 6
- 239000011347 resin Substances 0.000 claims abstract description 6
- 229920005989 resin Polymers 0.000 claims abstract description 6
- 239000000243 solution Substances 0.000 claims description 24
- 239000000463 material Substances 0.000 claims description 14
- 238000010438 heat treatment Methods 0.000 claims description 9
- 239000002184 metal Substances 0.000 claims description 9
- 238000007790 scraping Methods 0.000 claims description 9
- 238000002360 preparation method Methods 0.000 claims description 8
- 230000001954 sterilising effect Effects 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 5
- 239000011148 porous material Substances 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 5
- 238000010790 dilution Methods 0.000 claims description 4
- 239000012895 dilution Substances 0.000 claims description 4
- 238000007599 discharging Methods 0.000 claims description 4
- 230000033228 biological regulation Effects 0.000 claims description 3
- 230000008602 contraction Effects 0.000 claims description 3
- 235000013305 food Nutrition 0.000 claims description 3
- 230000036039 immunity Effects 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 238000000926 separation method Methods 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims 1
- 238000002791 soaking Methods 0.000 claims 1
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 abstract description 16
- 239000002126 C01EB10 - Adenosine Substances 0.000 abstract description 8
- 229960005305 adenosine Drugs 0.000 abstract description 8
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- 238000001035 drying Methods 0.000 description 7
- 239000003814 drug Substances 0.000 description 6
- 108010062580 Concanavalin A Proteins 0.000 description 5
- 241000699670 Mus sp. Species 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 238000003304 gavage Methods 0.000 description 4
- 210000004698 lymphocyte Anatomy 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000005611 electricity Effects 0.000 description 3
- 239000012467 final product Substances 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 230000035755 proliferation Effects 0.000 description 3
- 238000000746 purification Methods 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 102000011782 Keratins Human genes 0.000 description 2
- 108010076876 Keratins Proteins 0.000 description 2
- LAZPBGZRMVRFKY-HNCPQSOCSA-N Levamisole hydrochloride Chemical group Cl.C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 LAZPBGZRMVRFKY-HNCPQSOCSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 239000012531 culture fluid Substances 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000013558 reference substance Substances 0.000 description 2
- 230000003393 splenic effect Effects 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000003643 water by type Substances 0.000 description 2
- 206010003497 Asphyxia Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 235000000525 Dimocarpus longan Nutrition 0.000 description 1
- 238000012449 Kunming mouse Methods 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 229960003734 levamisole hydrochloride Drugs 0.000 description 1
- GBMDVOWEEQVZKZ-UHFFFAOYSA-N methanol;hydrate Chemical compound O.OC GBMDVOWEEQVZKZ-UHFFFAOYSA-N 0.000 description 1
- YTJSFYQNRXLOIC-UHFFFAOYSA-N octadecylsilane Chemical compound CCCCCCCCCCCCCCCCCC[SiH3] YTJSFYQNRXLOIC-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 210000004988 splenocyte Anatomy 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
nullThe present invention provides the extracting method of a kind of Arillus Longan，Take Arillus Longan，Water with 10 times of weight of Arillus Longan，Soak 0.5h，Decoct 1 hour，Filter，Medicinal residues add the water of 8 times of weight of medical material，Decoct 1 hour，Medicinal liquid leaches，Merge twice decoction liquor，Being concentrated into 60 DEG C of relative densities is 1.05，Adding ethanol makes the percent by volume of alcohol content reach 75%，Stirring，Stand，Filter，When filtrate is concentrated into 65 DEG C, relative density is 1.25，And reclaim ethanol，Obtain concentrated solution，Use silica gel refines，In advance selected silica gel is loaded in resin column，After purified for described concentrated solution water being diluted simultaneously，By reverse phase silica gel post，Remove the impurity in liquid，Collect whole effluent，Continue to concentrate，Concentrated solution is dried,Pelletize，Obtain Arillus Longan granule，Prepare adenosine content high，And and agrimophol、Quercetin compatibility is prepared as Arillus Longan beverage.
Description
Technical field
The present invention relates to food extractive technique field, be specifically related to extracting method and the Arillus Longan beverage of a kind of Arillus Longan.
Background technology
Arillus Longan extracting method in prior art, technique is coarse, backward, and impurity is many, and active constituent content is low, causes patient
Consumption is excessive, it has not been convenient to take, and has had a strong impact on this product and has applied clinically.
Summary of the invention
Goal of the invention: in order to solve the problems referred to above, it is an object of the invention to provide extracting method and the dragon of a kind of Arillus Longan
Eye meat beverage.
Technical scheme: it is an object of the invention to by following scheme realization:
The extracting method of a kind of Arillus Longan, preparation method is: take Arillus Longan, adds the water of 10 times of weight of Arillus Longan, soaks 0.5h, decocts
Boiling 1 hour, filter, medicinal residues add the water of 8 times of weight of medical material, decoct 1 hour, and medicinal liquid leaches, and merges twice decoction liquor, concentrate
Being 1.05 to 60 DEG C of relative densities, add ethanol and make the percent by volume of alcohol content reach 75%, stirring, standing, filtration, filtrate concentrates
It is 1.25 to relative density when 65 DEG C, and reclaims ethanol, obtain concentrated solution, use silica gel to refine, in advance selected silica gel is loaded
In resin column, after being diluted by purified for described concentrated solution water, by reverse phase silica gel post, remove the impurity in liquid simultaneously, collect
All effluent, continue to concentrate, are dried by concentrated solution, pelletize, obtain Arillus Longan granule.
The extracting method of described Arillus Longan, silica gel specific surface described in preparation method is 300～500m2/g, and pore volume is 0.70
～0.90ml/g, after described dilution, concentrated solution is by the separation of reverse phase silica gel post, eluting, to only going out water colorless.
The extracting method of described Arillus Longan, concentrates in said extracted method and uses device, including tank body, be arranged on described tank body
On charging aperture and be arranged on the discharge nozzle of described tank base, described discharge nozzle is provided with discharge valve and filter,
It is provided with shaft in described tank body, described shaft is provided with stirring paddle, be provided with and described stirring at the top of described tank body
The stirring motor that axle is connected, the diapire in described tank body is provided with vibrations chamber, is provided with jolting plate at described vibrations intracavity, in institute
State and be provided with electromagnetic shaker between jolting plate and described vibrations chamber, the sidewall in described tank body is provided with cavity, at described jolting plate
End face be provided with scraper plate, between described scraper plate and described cavity, be provided with telescopic cylinder, described scraper plate is at described telescopic cylinder
Effect is lower realizes the scraping to jolting plate surface, is provided with the discharging being connected with described discharge nozzle at the center of described jolting plate
Mouthful.
The extracting method of described Arillus Longan, jolting plate described in enrichment facility and the connection in described vibrations chamber in said extracted method
Place is provided with sealing metal bar, is provided with the shake control device being connected with described electromagnetic shaker on described tank body, described in enrichment facility
The bottom of scraper plate is provided with metal scraping layer, and described metal scraping layer is pressed on described jolting plate, described tank body is provided with
The extension and contraction control button that described telescopic cylinder is connected, is provided with water tester, in described discharging in tank body described in enrichment facility
Cooler it is provided with in pipe.
The extracting method of described Arillus Longan, is dried in said extracted method and uses device, including casing, be arranged on described casing
Interior material frame and the blast pipe and the discharge pipe that are arranged on described casing top, it is characterised in that: in the sidewall of described casing
It is provided with the air intake passage being connected with described blast pipe, the sidewall of described casing is provided with and is connected with described air intake passage
Air holes, described discharge pipe through described casing roof connection casing in casing outside, also set in the sidewall of described casing
Having homoiothermic chamber and sterilization chamber, be provided with electrical heating block at described homoiothermic intracavity, described air intake passage passes described regulation chamber and sterilizing
Chamber is arranged, and is provided with rotating drum, is provided with electric rotating machine in described rotating drum in the diapire of described casing, described electric rotating machine
Main shaft is connected with described material frame, is provided with vibrations groove in described material frame, and the end face at described material frame is provided with and holds
Plate, is provided with shaking device described holding between plate and described vibrations groove.
The extracting method of described Arillus Longan, is dried in said extracted method and uses shaking device described in device to include driving electricity
Machine, is arranged on the eccentric on described driving electric machine main shaft, the wheel limit of described eccentric be pressed on described in hold in the bottom surface of plate
The heart, is provided with extension spring between the diapire of the described bottom holding plate and described vibrations groove, and described extension spring with described eccentric is
Centrosymmetry is arranged.
The extracting method of described Arillus Longan, is dried in said extracted method in using casing described in device and is provided with temperature sensing
Device, is provided with the driver being connected with described temperature sensor in the sidewall of described casing, and described driver adds with described electricity
The control end of hot block is connected, and is additionally provided with chamber door on described casing.
A kind of Arillus Longan beverage, said method the Arillus Longan granule prepared, agrimophol, Quercetin form.
Described Arillus Longan beverage, Arillus Longan granule, agrimophol, the weight ratio of Quercetin are 2-6:1-4:2-5.
Described Arillus Longan beverage improves the application in immunity food in preparation suppression.
Arillus Longan (formal name used at school: Dimocarpus longan Lour.), also known as Arillus Longan, Fructus Alpiniae Oxyphyllae.Aiphyllium, high usual more than 10
Rice；Sprig is sturdy, by micro-pubescence, scattered pale asphyxia hole skin.It is long 15-30 centimetre or longer that leaf connects handle；4-5 pair, lobule, thin keratin,
Long round shape is oval to long round shape lanceolar, and both sides are the most asymmetric；Petiolule length is typically not greater than 5 millimeters.Inflorescence is large-scale, many points
Branch；Bennet is short；The nearly keratin of sepal, triangular shape is avette；Petal milky, lanceolar, the most isometric with sepal, only outside is by micro-soft
Hair；Filigree is by short bristle.The most subsphaeroidal, usual yellowish-brown or sometimes lark, outside is the most coarse, or the tubercle of rare dimpling
Body；Seed dark brown, light, is all wrapped up by the aril of meat.Between florescence spring and summer, really summer phase.Arillus Longan in the present invention
For Arillus Longan.
In prior art, the original extracting method of Arillus Longan, technique is coarse, backward, and impurity is many, causes patient's consumption excessive,
Being inconvenient to take, adenosine content prepared by the present invention increases, and content is high.Concentrator simple in construction in the present invention, operation are just
Victory, it is provided with jolting plate and electromagnetic shaker, and is additionally provided with scraper plate and the telescopic cylinder being connected with described scraper plate, can effectively prevent tank
Luming bottom body, be greatly improved the efficiency of heating surface to a certain extent, it is easy to efficiently solve in conventional art Chinese medicinal concentration equipment
Luming bottom appearance and affect the technical deficiency of the efficiency of heating surface, stability in use is good and the suitability strong, and the effective ingredient of medicine is steady
Determine not to be destroyed.This drying equipment structure is simple, simple and quick, and it uses wall box to blow, and is additionally arranged electricity
Heat block, can be adjusted according to the temperature in case, thus ensure that the stability of baking temperature, and be provided with electric rotating machine
And shaking device, can rotate and shake holding plate while heating, thus medicine local desiccation can be prevented, thus one
Determine can improve in degree dry efficiency, solve the technical deficiency that the drying device drying efficiency of conventional art is low.
Accompanying drawing explanation
In order to make present disclosure be more likely to be clearly understood, below according to specific embodiment and combine accompanying drawing, right
The present invention is described in further detail, wherein:
Fig. 1 is the structural representation of enrichment facility of the present invention.
Fig. 2 is the structural representation of drying device of the present invention.
Detailed description of the invention
Form by the following examples, is described in further detail the foregoing of the present invention again, but should be by this
Being interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to Examples below, all technology realized based on foregoing of the present invention are equal
Belong to the scope of the present invention.
Embodiment 1
Taking Arillus Longan 1000g, add the water of 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add medical material 8
The water of times weight, decocts 1 hour, and medicinal liquid leaches, and merges twice decoction liquor, and being concentrated into 60 DEG C of relative densities is 1.05, adds ethanol
The percent by volume making alcohol content reaches 75%, and stirring, standing, filtration, when filtrate is concentrated into 65 DEG C, relative density is 1.25, and returns
Receive ethanol, obtain concentrated solution, use silica gel to refine, obtain effluent, continue to concentrate, concentrated solution is dried, pelletize, obtain Arillus Longan
Granule.
The extracting method of described Arillus Longan, described silica gel process for purification is: load in resin column by selected silica gel in advance, with
Time by purified for described concentrated solution water dilute after, by reverse phase silica gel post, remove the impurity in liquid, collect whole effluent.
The extracting method of described Arillus Longan, described silica gel specific surface is 300m2/ g, pore volume is 0.90ml/g, after described dilution
Concentrated solution is separated by reverse phase silica gel post, eluting, to only going out water colorless.
See Fig. 1: the extracting method of described Arillus Longan, concentrate for above-mentioned three times and use device, including tank body 1, be arranged on described tank
Charging aperture on body 12 and be arranged on the discharge nozzle 3 bottom described tank body 1, is provided with discharge valve 4 and mistake on described discharge nozzle 3
Filter 5, is provided with shaft 6 in described tank body 1, is provided with stirring paddle 7 on described shaft 6, sets at the top of described tank body 1
Having the stirring motor 8 being connected with described shaft 6, the diapire in described tank body 1 is provided with vibrations chamber 9, in described vibrations chamber 9
Inside it is provided with jolting plate 10, between described jolting plate 10 and described vibrations chamber 9, is provided with electromagnetic shaker 11, shake can be made by electromagnetic shaker
Dynamic plate vibrations, thus can effectively prevent drug particles from concentrating on jolting plate, thus can prevent drug particles from tying on jolting plate
Block, the sidewall in described tank body 1 is provided with cavity 12, and the end face at described jolting plate 10 is provided with scraper plate 13, at described scraper plate
It is provided with telescopic cylinder 14 between 13 and described cavity 12, telescopic cylinder can be controlled as required, make scraper plate at the table of jolting plate
Face scrapes, thus the drug particles that part concentrates at jolting plate surface scrapes, and described scraper plate 13 is at described telescopic cylinder 14
The effect lower scraping realized jolting plate 10 surface, is provided with at the center of described jolting plate 10 and is connected with described discharge nozzle 3
Discharging opening 15.
It is provided with sealing metal bar 16 in the junction of described jolting plate 10 with described vibrations chamber 9, described tank body is provided with
The shake control device 17 being connected with described electromagnetic shaker.
Be provided with metal scraping layer 18 in the bottom of described scraper plate, described metal scraping layer is pressed on described jolting plate,
Described tank body is provided with the extension and contraction control button 19 being connected with described telescopic cylinder.
In described tank body, it is provided with water tester 21, in described discharge nozzle, is provided with cooler 20.
See Fig. 2: the extracting method of described Arillus Longan, above-mentioned dry use device, including casing 1, be arranged in described casing 1
Material frame 2 and be arranged on blast pipe 3 and the discharge pipe 4 at described casing 1 top, be provided with and institute in the sidewall of described casing 1
State the air intake passage 5 that blast pipe 3 is connected, the sidewall of described casing 1 is provided with the air holes being connected with described air intake passage 5
6, fresh air inlet is arranged on sidewall, it is ensured that the uniformity of ventilation, and can be greatly improved the contact area with medicine, institute
State discharge pipe 4 interior outside with casing 1 through the roof connection casing 1 of described casing 1, be additionally provided with in the sidewall of described casing 1
Homoiothermic chamber 7 and sterilization chamber 8, be provided with electrical heating block 9 in described homoiothermic chamber 7, and being provided with electrical heating block can be as required to air intake
The temperature of pipe is adjusted, it is ensured that the stability of baking temperature, and described air intake passage 5 sets through described regulation chamber 7 and sterilization chamber 8
Put, in the diapire of described casing 1, be provided with rotating drum 10, in described rotating drum 10, be provided with electric rotating machine 11, described electric rotating
The main shaft of machine 11 is connected with described material frame 2, is provided with vibrations groove 12, on the top of described material frame 2 in described material frame 2
Face is provided with and holds plate 13, is provided with shaking device 14 described holding between plate 13 and described vibrations groove 12.
Described shaking device 14 includes driving motor 141, is arranged on the eccentric 142 on described driving motor 141 main shaft,
The wheel limit of described eccentric 142 holds the bottom center of plate 13 described in being pressed on, in the described bottom holding plate 13 and described shake
Being provided with extension spring 15 between the diapire of dynamic groove 12, described extension spring is symmetrical arranged centered by described eccentric, passes through in use
Compressing of eccentric makes to hold plate rising, when the recess of eccentric compresses and holds plate, holds plate and resets under the effect of extension spring,
Make the disengaging of thing material fall again after holding plate in dropping process and hold the vibrations realizing material on plate.
In described casing 1, it is provided with temperature sensor 16, is provided with in the sidewall of described casing and described temperature sensor
The driver 17 being connected, described driver is connected with the control end of described electrical heating block.Temperature passes dry device and driver is
Existing prior art on market, it has only to when using and connecting connect according to corresponding connection description.
Described casing is additionally provided with chamber door 18.
Take Arillus Longan granule that said method prepares, agrimophol, the weight ratio of Quercetin are 4:3:4, side routinely
Method is prepared as beverage.
Embodiment 2
Taking Arillus Longan 1000g, add the water of 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add medical material 8
The water of times weight, decocts 1 hour, and medicinal liquid leaches, and merges twice decoction liquor, and being concentrated into 60 DEG C of relative densities is 1.05, adds ethanol
The percent by volume making alcohol content reaches 75%, and stirring, standing, filtration, when filtrate is concentrated into 65 DEG C, relative density is 1.25, and returns
Receive ethanol, obtain concentrated solution, use silica gel to refine, obtain effluent, continue to concentrate, concentrated solution is dried, pelletize, obtain Arillus Longan
Granule.
The extracting method of described Arillus Longan, described silica gel process for purification is: load in resin column by selected silica gel in advance, with
Time by purified for described concentrated solution water dilute after, by reverse phase silica gel post, remove the impurity in liquid, collect whole effluent.
The extracting method of described a kind of Arillus Longan, described silica gel specific surface is 500m2/g, and pore volume is 0.70ml/g, described dilute
Release rear concentrated solution and pass through the separation of reverse phase silica gel post, eluting, to only going out water colorless.
Concentrate with drying equipment ibid.
Take Arillus Longan granule that said method prepares, agrimophol, the weight ratio of Quercetin are 4:1:5, side routinely
Method is prepared as beverage.
Embodiment 3
Taking Arillus Longan 1000g, add the water of 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add medical material 8
The water of times weight, decocts 1 hour, and medicinal liquid leaches, and merges twice decoction liquor, and being concentrated into 60 DEG C of relative densities is 1.05, adds ethanol
The percent by volume making alcohol content reaches 75%, and stirring, standing, filtration, when filtrate is concentrated into 65 DEG C, relative density is 1.25, and returns
Receive ethanol, obtain concentrated solution, use silica gel to refine, obtain effluent, continue to concentrate, concentrated solution is dried, pelletize, obtain Arillus Longan
Granule.
The extracting method of described Arillus Longan, described silica gel process for purification is: load in resin column by selected silica gel in advance, with
Time by purified for described concentrated solution water dilute after, by reverse phase silica gel post, remove the impurity in liquid, collect whole effluent.
The extracting method of described Arillus Longan, described silica gel specific surface is 400m2/g, and pore volume is 0.80ml/g, after described dilution
Concentrated solution is separated by reverse phase silica gel post, eluting, to only going out water colorless.
Concentrate with drying equipment ibid.
Take Arillus Longan granule that said method prepares, agrimophol, the weight ratio of Quercetin are 4:4:2, according to a conventional method
It is prepared as beverage.
In above-described embodiment, Arillus Longan meets standards of pharmacopoeia, and agrimophol (40%), Quercetin (30%) are raw purchased from Shaanxi AOC
Thing Science and Technology Ltd..
Embodiment 4: by preparing the longan beverage without agrimophol in embodiment 1.
Embodiment 5: by preparing the longan beverage without Quercetin in embodiment 1.
Embodiment 6: Determination of Adenosine experimentation data in longan beverage of the present invention
1.1 Experimental agents: longan beverage of the present invention: prepare by embodiment 1-3 method.Matched group is that the employing of Arillus Longan granule is general
Logical concentrate and prepared by drying means, take Arillus Longan granule that said method prepares, agrimophol, the weight ratio of Quercetin are 4:3:
4, it is prepared as beverage according to a conventional method.
1.2 instruments: high performance liquid chromatograph system includes high performance liquid chromatograph (Waters 515)；P200 high-pressure pump；
Waters 2487 UV-detector and GJ605 type high pressure six-way injection valve；Chromatographic column be BDS HYPERSIL-C18 (4.6mm ×
250mm, 5 μm)；Data acquisition and process use HS Data Processing in Chromatography Workstation V4.0+ (Hangzhou English spectrum science and technology)
1.3 condition determinations: measure according to high performance liquid chromatography (general rule 0512).Chromatographic condition and system suitability with
Octadecylsilane chemically bonded silica is filler；With methanol-water (60:40) for flowing phase；Detection wavelength is 250nm；Theoretical plate
Number is calculated by adenosine peak should be not less than 2000.Take adenosine reference substance appropriate, accurately weighed, add methanol and make every lm l containing 5ug's
Solution, to obtain final product.The preparation of need testing solution takes this product under content uniformity item, finely ground, takes about
0.5g, accurately weighed, put in 25ml measuring bottle, add methanol 20ml, supersound process (power 250W, frequency 40kHz) 30
Minute, let cool, add methanol to scale, shake up, filter, take subsequent filtrate, to obtain final product.Precision draws reference substance solution and test sample respectively
The each 20ul of solution injects chromatograph of liquid, measures, to obtain final product.
1.4 experimental result
Determination of Adenosine result in longan beverage prepared by each embodiment
| Sample source | Adenosine content (%) |
| Embodiment 1 | 3.1 |
| Embodiment 2 | 4.2 |
| Embodiment 3 | 3.5 |
| Matched group | 1.2 |
According to the result of the test of upper table, in longan beverage prepared by embodiment of the present invention 1-3, adenosine content is the highest
In matched group.
Embodiment 7: the present invention improves the pharmacodynamic study of immunity
Experiment purpose: with the embodiment of the present invention 1,4,5 gavage mice 30d, compare the present invention and normal group mice by ConA
The difference of the splenic lymphocyte proliferation of induction, judges whether the present invention strengthens splenic lymphocyte proliferation.
Laboratory animal: Kunming mouse, male, body weight 18-22g, Shanghai Slac Experimental Animal Co., Ltd. provides, raw
Produce licence: SCXK (Shanghai) 2007-0005.
Experimental agents: prepare by the preparation method of above-described embodiment 1,4,5.
Experimental procedure: mice, is grouped by body weight stratified random, often group 12.As shown in the table, normal group gavage feeds water；
Levamisole hydrochloride group gavage levamisole hydrochloride；Embodiment 1,4,5 gavage 2g kg-1, the continuous gastric infusion 30d of each group.Nothing
Bacterium takes spleen, and according to being conventionally produced individual cells suspension, adjusting cell concentration is 5 × 105Individual/mL.Splenocyte suspension is added in
In 24 orifice plates, every hole 1mL, every animal sets two multiple holes, and (adding 50uL PRMI1640 culture fluid) is normally cultivated in a hole；One hole
Add 50uL concanavalin A, Con A (ConA) liquid (final concentration of 4.76ug/mL).It is placed in 5%CO2, 37 DEG C of CO2Incubator is cultivated 48h.Real
Testing 4h before end, every hole sucks supernatant 700uL, adds the 700uL PRMI1640 culture fluid without hyclone, the most every
Hole adds the MTT liquid of 50uL 5mg/mL.After cultivation terminates, every hole adds 1mL acid isopropyl alcohol, and careful piping and druming is uniformly to purple
Crystallization is all dissolved.Being dispensed into before detection in 96 well culture plates, 4 multiple holes are made in every hole, measure its optical density at 570nm wavelength
Value.
Experimental result:
The present invention impact on spleen lymphocyte proliferation
Note: compared with normal groupP ＜ 0.01,P ＜ 0.05.
Conclusion: the rate of increase conversion values after the embodiment of the present invention 1,4,5 mouse spleen lymphocyte is induced by ConA is higher than
Normal group mice, wherein embodiment 1 is better than embodiment 4,5, illustrates that Arillus Longan, agrimophol, Quercetin compatibility using effect are more preferable.
Claims (10)
1. the extracting method of an Arillus Longan, it is characterised in that preparation method is: take Arillus Longan, with the water of 10 times of weight of Arillus Longan,
Soaking 0.5h, decoct 1 hour, filter, medicinal residues add the water of 8 times of weight of medical material, decoct 1 hour, and medicinal liquid leaches, and merges twice
Decoction liquor, being concentrated into 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, stand, mistake
Filter, when filtrate is concentrated into 65 DEG C, relative density is 1.25, and reclaims ethanol, obtains concentrated solution, uses silica gel to refine, in advance will be selected
Silica gel load in resin column, after purified for described concentrated solution water being diluted, by reverse phase silica gel post, remove in liquid simultaneously
Impurity, collects whole effluent, continues to concentrate, is dried by concentrated solution, pelletizes, obtain Arillus Longan granule.
The extracting method of Arillus Longan the most according to claim 1, it is characterised in that silica gel specific surface described in preparation method is 300
～500m2/ g, pore volume is 0.70～0.90ml/g, and after described dilution, concentrated solution is by the separation of reverse phase silica gel post, eluting, to water outlet
Colourless only.
The extracting method of Arillus Longan the most according to claim 1, it is characterised in that concentrate in said extracted method and use device, bag
Include tank body, the charging aperture being arranged on described tank body and the discharge nozzle being arranged on described tank base, described discharge nozzle sets
There are discharge valve and filter, in described tank body, are provided with shaft, described shaft is provided with stirring paddle, at described tank body
Top be provided with the stirring motor being connected with described shaft, the diapire in described tank body be provided with vibrations chamber, in described shake
Dynamic intracavity is provided with jolting plate, is provided with electromagnetic shaker, on the sidewall in described tank body between described jolting plate and described vibrations chamber
Being provided with cavity, the end face at described jolting plate is provided with scraper plate, is provided with telescopic cylinder between described scraper plate and described cavity, described
Scraper plate realizes the scraping to jolting plate surface under the effect of described telescopic cylinder, is provided with described at the center of described jolting plate
The discharging opening that discharge nozzle is connected.
The extracting method of Arillus Longan the most according to claim 3, it is characterised in that shake described in enrichment facility in said extracted method
Dynamic plate is provided with sealing metal bar with the junction in described vibrations chamber, is provided with the shake being connected with described electromagnetic shaker on described tank body
Movement controller, the bottom of scraper plate described in enrichment facility is provided with metal scraping layer, and described metal scraping layer is pressed on described jolting plate
On, described tank body is provided with the extension and contraction control button being connected with described telescopic cylinder, is provided with in tank body described in enrichment facility
Water tester, is provided with cooler in described discharge nozzle.
The extracting method of Arillus Longan the most according to claim 1, it is characterised in that be dried in said extracted method and use device, bag
Including casing, the material frame being arranged in described casing and the blast pipe and the discharge pipe that are arranged on described casing top, its feature exists
In: in the sidewall of described casing, it is provided with the air intake passage being connected with described blast pipe, the sidewall of described casing is provided with
The air holes being connected with described air intake passage, described discharge pipe through described casing roof connection casing in casing outside,
Being additionally provided with homoiothermic chamber and sterilization chamber in the sidewall of described casing, be provided with electrical heating block at described homoiothermic intracavity, described air intake leads to
Road is arranged through described regulation chamber and sterilization chamber, is provided with rotating drum, is provided with in described rotating drum in the diapire of described casing
Electric rotating machine, the main shaft of described electric rotating machine is connected with described material frame, is provided with vibrations groove in described material frame, in institute
State the end face of material frame to be provided with and hold plate, be provided with shaking device described holding between plate and described vibrations groove.
The extracting method of Arillus Longan the most according to claim 5, it is characterised in that be dried in said extracted method and use device institute
Stating shaking device to include driving motor, be arranged on the eccentric on described driving electric machine main shaft, the wheel limit of described eccentric compresses
In the described bottom center holding plate, between the diapire of the described bottom holding plate and described vibrations groove, it is provided with extension spring, institute
State extension spring to be symmetrical arranged centered by described eccentric.
The extracting method of Arillus Longan the most according to claim 5, it is characterised in that be dried in said extracted method and use device institute
It is provided with temperature sensor in stating casing, in the sidewall of described casing, is provided with the driver being connected with described temperature sensor,
Described driver is connected with the control end of described electrical heating block, is additionally provided with chamber door on described casing.
8. a longan beverage, it is characterised in that by the Arillus Longan granule prepared in claim 1, agrimophol, Quercetin
Composition.
Longan beverage the most according to claim 7, it is characterised in that Arillus Longan granule, agrimophol, the weight ratio of Quercetin are
2-6:1-4:2-5.
Longan beverage application in preparation improves immunity food the most according to claim 9.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106117278A (en) * | 2016-06-14 | 2016-11-16 | 南京华宽信息咨询中心 | The extracting method of a kind of rhodioside and rhodioside extract |
| CN112915025A (en) * | 2021-01-27 | 2021-06-08 | 河南科技大学第一附属医院 | Timed automatic medicine dispensing device for nursing old people |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010077055A (en) * | 2000-01-31 | 2001-08-17 | 강대주 | Process for Preparing Rice Wine Containing Bamboo Components |
| CN101297864A (en) * | 2008-06-27 | 2008-11-05 | 广州星群（药业）股份有限公司 | Preparation of Xia sang ju formulation |
| CN101791119A (en) * | 2010-02-03 | 2010-08-04 | 孟蒙 | Chaga nutrient composition |
| CN102715503A (en) * | 2012-06-18 | 2012-10-10 | 河南正昌生物医药科技有限公司 | Immunity-regulating TCM (traditional Chinese medicine) health food and preparation method thereof |
| CN103923152A (en) * | 2014-05-08 | 2014-07-16 | 济南汉定生物工程有限公司 | Method for extracting mogroside V |
| CN104840587A (en) * | 2015-04-02 | 2015-08-19 | 广西大学 | Method for extracting longan seed polyphenol |
-
2016
- 2016-07-30 CN CN201610622512.0A patent/CN106235331A/en not_active Withdrawn
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010077055A (en) * | 2000-01-31 | 2001-08-17 | 강대주 | Process for Preparing Rice Wine Containing Bamboo Components |
| CN101297864A (en) * | 2008-06-27 | 2008-11-05 | 广州星群（药业）股份有限公司 | Preparation of Xia sang ju formulation |
| CN101791119A (en) * | 2010-02-03 | 2010-08-04 | 孟蒙 | Chaga nutrient composition |
| CN102715503A (en) * | 2012-06-18 | 2012-10-10 | 河南正昌生物医药科技有限公司 | Immunity-regulating TCM (traditional Chinese medicine) health food and preparation method thereof |
| CN103923152A (en) * | 2014-05-08 | 2014-07-16 | 济南汉定生物工程有限公司 | Method for extracting mogroside V |
| CN104840587A (en) * | 2015-04-02 | 2015-08-19 | 广西大学 | Method for extracting longan seed polyphenol |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106117278A (en) * | 2016-06-14 | 2016-11-16 | 南京华宽信息咨询中心 | The extracting method of a kind of rhodioside and rhodioside extract |
| CN112915025A (en) * | 2021-01-27 | 2021-06-08 | 河南科技大学第一附属医院 | Timed automatic medicine dispensing device for nursing old people |
| CN112915025B (en) * | 2021-01-27 | 2022-06-10 | 河南科技大学第一附属医院 | Timed automatic medicine dispensing device for nursing old people |
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