CN106234841A - A kind of carp kidney cell mixed feed containing defat krill meal and preparation method thereof - Google Patents
A kind of carp kidney cell mixed feed containing defat krill meal and preparation method thereof Download PDFInfo
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- CN106234841A CN106234841A CN201610626335.3A CN201610626335A CN106234841A CN 106234841 A CN106234841 A CN 106234841A CN 201610626335 A CN201610626335 A CN 201610626335A CN 106234841 A CN106234841 A CN 106234841A
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
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Abstract
The invention discloses a kind of carp kidney cell mixed feed containing defat krill meal and preparation method thereof, wherein mixed feed includes following raw material: bean cake, cottonseed meal, flour, corn DDGS, rapeseed meal, garlicin, maize germ cake, Testa oryzae, fish flour, defat krill meal and duck are oily；Its preparation method comprises the following steps: destruction step, batching step, granulation step.The invention has the beneficial effects as follows: the feedstuff of the present invention contains the medicated premix with invigorating spleen and reinforcing stomach, benefiting vital QI for tranquillizing, there is the course for the treatment of shorter, curative effect is preferable, drug residue free, the advantage that cost price is cheap, the feedstuff that medicated premix contains defat krill meal with other cooperates, interact, it is possible to the nutritional need of full carp kidney cell, improve rate of body weight gain and rate of growth, significantly reduce feed coefficient regulating liver-QI body ratio, after this type of Cyprinus carpio meat edible, also body can be played certain health-care effect.
Description
Technical field
The present invention relates to bird feed, particularly to a kind of carp kidney cell mixed feed containing defat krill meal and preparation thereof
Method.
Background technology
Along with the sustainable development of culture fishery, drive the fast development of aquatic feeds industry.And egg in aquatic feeds
White choosing of raw material not only directly affects quality of the fodder and price, has an effect on the comprehensive benefit of whole aquatic products industry.Fish flour has
The major protein source of the advantages, always aquatic feeds such as aminoacid Compositional balance, easy to digest, good palatability, is also to constitute feedstuff
The main component of cost, due to fish flour demand increase and supply keeps relative stability, therefore, fish flour is the most always
Maintain higher price.Being limited by feed cost, fish flour usage amount in some fresh water fish feed formula is compressed continuously.
Current research is concentrated mainly on plant protein source, but owing to nutritive value is relatively low, amino acid imbalance, palatability is poor, and
Rich in antinutritional factor, it is generally not capable of meeting growth of animal demand, and defat krill meal is as the exploitation in a kind of high-quality protein source
Utilize the important measures solving this imbalance between supply and demand beyond doubt.
The defat krill meal that krill convection drying obtains is that (protein content ＞ 50% depends on adding in a kind of high-quality protein source
Work mode), rich in unsaturated fatty acid, phospholipid and astaxanthin, additionally containing two English of denier, many chlorine in defat krill meal
Biphenyl (Polychlorinated biphenyls, PCB) and heavy metal, this becomes irreplaceable feedstuff
(Bustos et al,1999).It has been investigated that, in South Pole defat krill meal, total lipid content is up to 11.37%, mainly with glycerol
Three esters, phospholipid and free fatty are main, and in phospholipid and free fatty, content of polyunsaturated fatty acid enriches, and is respectively
49.96% and 48.50%.Existing research shows, in defat krill meal, content astaxanthin is 100～300mg/kg, and it is freely
Base cancellation vigor is 100 times of vitamin E, the most also has and improves immunity and improve the effect of fertility.Institute in Antarctic krill
Rich in mineral element (copper 101mg/kg, selenium 12mg/kg, zinc 72mg/kg, calcium 1.7%, phosphorus 1.3%), be that biological institute is necessary
Nutrient substance, the body demand to mineral can be met well.Research finds, Antarctic krill is rich in zinc, magnesium, phosphorus, selenium etc.
The nutrient of needed by human, can be as a kind of high-quality animality mineral origin.
Summary of the invention
The technical problem to be solved is to be to provide a kind of carp kidney cell mixed feed containing defat krill meal,
Using the Feed Energy containing this medicated premix to overcome the various defects of Chinese medicine of the prior art and Western medicine, the present invention raises
Material contains the medicated premix with invigorating spleen and reinforcing stomach, benefiting vital QI for tranquillizing, has the course for the treatment of shorter, and curative effect is preferable, drug residue free, cost
Cheap advantage, the feedstuff that medicated premix contains defat krill meal with other cooperates, and interacts, it is possible to
The nutritional need of full carp kidney cell, improves rate of body weight gain and rate of growth, significantly reduces feed coefficient regulating liver-QI body ratio, this type of Cyprinus carpio edible
Also body can be played certain health-care effect after meat.
In order to realize foregoing invention purpose, the invention provides a kind of carp kidney cell mixed feed containing defat krill meal,
Wherein, described feedstuff includes following raw material: bean cake, cottonseed meal, flour, corn DDGS, rapeseed meal, garlicin, maize germ cake,
Testa oryzae, fish flour, defat krill meal and duck oil.
Described mixed feed is made up of the raw material of following parts by weight: bean cake 100-300 weight portion, cottonseed meal 70-200 weight
Amount part, flour 90-160 weight portion, corn DDGS 50-150 weight portion, rapeseed meal 80-220 weight portion, garlicin 6-12 weight
Part, maize germ cake 70-140 weight portion, Testa oryzae 10-40 weight portion, fish flour 20-100 weight portion, defat krill meal 0-80 weight
Part and duck oil 15-25 weight portion.
Described mixed feed is made up of the raw material of following parts by weight: bean cake 200 weight portion, cottonseed meal 150 weight portion, face
Powder 120 weight portion, corn DDGS 100 weight portion, rapeseed meal 130 weight portion, garlicin 9 weight portion, maize germ cake 110 weight
Part, Testa oryzae 20 weight portion, fish flour 40 weight portion, defat krill meal 40 weight portion and duck oil 21 weight portions.
Described mixed feed also includes medicated premix, and described mixed feed is made up of the raw material material of following parts by weight:
Bean cake 100-300 weight portion, cottonseed meal 70-200 weight portion, flour 90-160 weight portion, corn DDGS 50-150 weight portion, dish
Seed dregs of rice 80-220 weight portion, garlicin 6-12 weight portion, maize germ cake 70-140 weight portion, Testa oryzae 10-40 weight portion, fish flour
20-100 weight portion, defat krill meal 0-80 weight portion, duck oil 15-25 weight portion and medicated premix 20-50 weight portion.
Described additive for fodder is made up of the raw material of following parts by weight: bean cake 200 weight portion, cottonseed meal 150 weight
Amount part, flour 120 weight portion, corn DDGS 100 weight portion, rapeseed meal 130 weight portion, garlicin 9 weight portion, maize germ cake
110 weight portions, Testa oryzae 20 weight portion, fish flour 40 weight portion, defat krill meal 40 weight portion, duck oil 21 weight portions and medicine add
Agent 37 weight portion.
Described medicated premix is made up of the raw material of following parts by weight: Herba Hedyotis scabridae 6-12 weight portion, Fructus artocarpi lingnanensis 9-18 weight
Amount part, Lignum Poria 12-22 weight portion, Radix Codonopsis 2-8 weight portion, wing handle knotweed 7-16 weight portion, Fructus Alpiniae Oxyphyllae 10-22 weight portion, leaf three
Seven 8-15 weight portions, amur foxtail 11-21 weight portion, Radix Astragali 5-12 weight portion, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 13-26 weight portion, Ganoderma 10-22 weight
Part, Folium Lauri nobilis 12-34 weight portion, Radix Cudraniae 9-17 weight portion, Cortex Cinnamomi 15-35 weight portion, Corm Eleocharitis 9-14 weight portion, Radix Et Caulis Acanthopanacis Senticosi
13-27 weight portion and Herba Cirsii linearis 15-25 weight portion.
Described medicated premix is made up of the raw material of following parts by weight: Herba Hedyotis scabridae 8 weight portion, Fructus artocarpi lingnanensis 15 weight portion,
Lignum Poria 20 weight portion, Radix Codonopsis 4 weight portion, wing handle knotweed 14 weight portion, Fructus Alpiniae Oxyphyllae 15 weight portion, leaf Radix Notoginseng 13 weight portion, see wheat
Ma 20 weight portion, the Radix Astragali 7 weight portion, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 25 weight portion, Ganoderma 17 weight portion, Folium Lauri nobilis 32 weight portion, Radix Cudraniae 16 weight
Amount part, Cortex Cinnamomi 25 weight portion, Corm Eleocharitis 13 weight portion, Radix Et Caulis Acanthopanacis Senticosi 25 weight portion and Herba Cirsii linearis 19 weight portion.
The preparation method of described medicated premix comprises the following steps:
The first step, is mixed in proportion described each raw material, and adding relative to the determining alcohol of mixture quality 2～4 times is 85
～the ethanol of 95%, it is heated to reflux 1～3 hour, extracts, filter and obtain the first extracting solution；Filter the medicinal residues obtained and add phase
For described medicinal residues quality 1～the ethanol that determining alcohol is 85～95% of 2 times, it is heated to reflux 1～3 hour, extracts, filter and obtain
Second extracting solution；First extracting solution and the second extracting solution being merged, concentrating under reduced pressure removes alcohol solvent, is dried, it is thus achieved that dry cream；
Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, sieves, obtain
Obtain 300 mesh～the micropowders of 400 mesh, it is thus achieved that medicated premix powder.
Described defat krill meal is the defat krill meal that Wudi Yu Jin commerce and trade company limited produces, wherein, defat krill meal
Crude protein content be 68%, fat content is 6%.
In order to preferably realize foregoing invention purpose, the invention provides a kind of carp kidney cell containing defat krill meal and coordinate
The preparation method of feedstuff, described preparation method comprises the following steps:
(1) destruction step: weigh bean cake, cottonseed meal, corn DDGS, rapeseed meal, maize germ cake, rice by ratio of weight and the number of copies
Bran, puts into pulverizer and carries out Crushing of Ultrafine, crosses 2.0mm sieve after pulverizing；
(2) batching step: weigh flour, garlicin, fish flour, defat krill meal and duck oil and medicine according to ratio of weight and number
Additive, pulverizes, with step (1), the fine powder obtained and mixes, put into mixer, and mix homogeneously, incorporation time is 30-60s；
(3) granulation step: putting into granulator and pelletize, pelleting temperature is 85 DEG C so that it is gelatinization degree reaches more than 90%.
The invention has the beneficial effects as follows: the feedstuff of the present invention contains the medicated premix with invigorating spleen and reinforcing stomach, benefiting vital QI for tranquillizing,
Having the course for the treatment of shorter, curative effect is preferable, and drug residue free, the advantage that cost price is cheap, medicated premix contains defat with other
The feedstuff of krill meal cooperates, and interacts, it is possible to the nutritional need of full carp kidney cell, improves rate of body weight gain and growth
Rate, significantly reduces feed coefficient regulating liver-QI body ratio, after this type of Cyprinus carpio meat edible, body also can play certain health-care effect.
Detailed description of the invention
Medicated premix of the present invention follows the ultimate principle of " strengthening vital QI to eliminate pathogenic factors ", it then follows invigorating spleen and reinforcing stomach, the principle of benefiting vital QI for tranquillizing,
Providing a kind of carp kidney cell mixed feed containing defat krill meal, it includes that medicated premix, medicated premix include following
Raw material: Herba Hedyotis scabridae, Fructus artocarpi lingnanensis, Lignum Poria, Radix Codonopsis, wing handle knotweed, Fructus Alpiniae Oxyphyllae, leaf Radix Notoginseng, amur foxtail, the Radix Astragali, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), Ganoderma,
Folium Lauri nobilis, Radix Cudraniae, Cortex Cinnamomi, Corm Eleocharitis, Radix Et Caulis Acanthopanacis Senticosi and Herba Cirsii linearis.
The pharmacological property of above-mentioned each raw material is as follows:
Herba Cirsii linearis: another name: wild Flos Carthami, mountain Flos Carthami (" Zhejiang conventional medical herbs among the people ").Source: " Zhejiang conventional grass among the people
Medicine ".Source: for root or the flower of feverfew Herba Cirsii linearis.Adopt root autumn, using fresh herb or dry standby.Nature and flavor: acid, temperature.Cure mainly: live
Blood dissipating blood stasis, subduing swelling and detoxicating.
Corm Eleocharitis: another name: Chinese herbaceous peony, an ancient name for water chestnut, mushroom, water arum, crow taro, crow thatch, umbilicus, Black Hills rib, Di Li, toe calk, Horse hoof, red
Rhizoma sagittariae sagittifoliae, horse potato.Source: come from " daily book on Chinese herbal medicine ".Source: medical material Ji Yuan: for the bulb of sedge Corm Eleocharitis.Latin plant moves
Thing mineral name: Eleocharis dulcis (Burm.f.) Trin.ex Henschel [Andropogon dulcis
Burm.f.；Scirpus plantaginea Retz.；Heleochuris plantaginea R.Br.；Eleocharis
Tuberosa Schult] to gather and store: winter excavates, and cleans earth, using fresh herb or air-dried.Nature and flavor: sweet in the mouth；Cold in nature.Gui Jing:
Lung；Stomach warp.Cure mainly: clearing away heat and promoting production of body fluid；Reduce phlegm；Removing food stagnancy.Main epidemic febrile disease is thirsty；Laryngopharynx swelling and pain；Phlegm-heat cough；Conjunctival congestion；Quench one's thirst；Dysentery；
Jaundice；Pyretic stranguria；Food stagnation；Wart.
Folium Lauri nobilis: source: medical material Ji Yuan: for the leaf of canella Laurel.Latin plant animal mineral name: Laurus
Nobilis L. gathers and stores: autumn gathers, and dries.Nature and flavor: pungent；Tepor.Cure mainly: stomach invigorating is regulated the flow of vital energy.
Cortex Cinnamomi: source: this product is the dry bark of canella Cortex Cinnamomi Cinnamomum cassia Presl.More than the autumn
Season strips, and dries in the shade.Nature and flavor: pungent, sweet are the warmmest.Gui Jing: return kidney, spleen, the heart, Liver Channel.Cure mainly: mend fire supporing yang, let the fire back to its origin, cold expelling
Pain relieving, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffer from a deficiency of the kidney and breathe heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness
Vomit and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.
Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae): another name: Radix Cissi Kerrii (" conventional Chinese herbal medicine color atlas "), stone qin potato, Stephania cepharatha Hayata (" Guangxi medium-height grass
Medicine "), DIWUGUI (Nanchuan " conventional Chinese herbal medicine handbook "), Radix Stephaniae Epigaeae (" mountain of papers Chinese herbal medicine ").Source: Guangzhou army " conventional medium-height grass
Medicine handbook ".Source: for the tuber of menispermaceous plants Radix Stephaniae Japonicae.The whole year can adopt.Clean, section, dry.Nature and flavor: Guangzhou army
" conventional Chinese herbal medicine handbook ": " bitter, cold." cure mainly: heat-clearing and toxic substances removing, benefiting stomach and stopping pain, dissipating blood stasis for subsidence of swelling.Control exogenous cough, pharyngalgia, dispute
Raw skin ulcer, vomiting and diarrhoea, dysentery, stomachache, swollen ulcer drug, traumatic injury.1. Guangzhou army " conventional Chinese herbal medicine handbook ": " heat clearing away solution
Poison, eliminating stasis to stop pain.Control stomach and duodenum is burst hemorrhoid pain, treating swelling and pain by traumatic injury, neuralgia, toothache, acute gastroenteritis, bacillary dysentery, above exhale
Suction road infects, pharyngalgia." 2. " conventional Chinese herbal medicine color atlas ": " benefiting stomach and stopping pain, subduing swelling and detoxicating." 3. Guangzhou air force " conventional medium-height grass
Medicine handbook ": " control pulmonary tuberculosis, ulcerative carbuncle, abscess, dyspepsia, stomatitis." 4. " mountain of papers Chinese herbal medicine ": " treats for stomachache, abdominal distention, abdomen
Rush down, malaria." 5. Nanchuan " conventional Chinese herbal medicine handbook ": " controls boil on the nape opposite the mouth and burn."
Amur foxtail: another name: ox head is violent, mountain Sorghum vulgare Pers., roadside paddy, the other paddy in road, Herba Leptochloae Chinensis, wooden club grass.Source: medical material Ji Yuan: for
The herb of grass amur foxtail.Latin plant animal mineral name: Alopecurus aequalis Sobol.
[Alopecurusamurensis (Kom.) Kom.] gathers and stores: spring, summer gather, and dry or using fresh herb.Nature and flavor: light；Cool.
Cure mainly: clearing away heat-damp and promoting diuresis；Antidiarrheal；Removing toxic substances.Main edema；Chickenpox；Have loose bowels；Icterohepatitis；Acute conjunctivitis；Venom.
Wing handle knotweed: source: medical material Ji Yuan: for the herb of polygonaceae plant Polygonum sinomontanum Sam..Latin plant animal mineral name:
Polygonum sinomontanum Sam. [P.bistorta auct.non L.] gathers and stores: gather between summer, autumn,
Dry.Nature and flavor: micro-sweet；Puckery；Cool in nature.Cure mainly: reason lung cough-relieving；Heat-clearing and toxic substances removing.Main anemopyretic cold；Cough due to lung-heat；Lung abscess；Have loose bowels；
Dysentery.
Fructus artocarpi lingnanensis: another name: Canis familiaris L. fruit (" south of the Five Ridges gather medicinal herbs record "), kermes public (Guangzhou army " commonly using Chinese herbal medicine handbook ").Source:
" Guangdong Chinese medicine " II.Source: for the fruit of moraceae plants osmanthus wood.Autumn gathers, and section is dried.Nature and flavor: Guangzhou army is " in Chang Yong
Medical herbs handbook ": " acid, flat." cure mainly: hemostasis of promoting the production of body fluid, appetizing is reduced phlegm.Control heat thirsty, hemoptysis, spit blood, epistaxis, laryngalgia, inappetence.
Lignum Poria: another name: yellow pine joint (" property of medicine opinion "), Lignum Pini Nodi (" exercise for beriberi is always "), Poria cum Radix Pini's heart (" precious mirror of hygiene "),
Poria cum Radix Pini's heart wood (essentials of Matea Medica).Source: " detailed outline ".Source: for the Radix Pini massonianae in the middle of Polyporaceae plant poria cocos sclerotium.Nature and flavor:
Sweet, flat.1. " book on Chinese herbal medicine is looked for the truth ": " bitter in the mouth, warm in nature." 2. " key medicine divides agent ": " is sweet, flat, nontoxic." cure mainly: suppressing the hyperactive liver is calmed the nerves.
Leaf Radix Notoginseng: another name: Herba Senecionis Chrysanthemoidis, Rhizoma Schizocapsae Plantagineae, the purple back of the body Radix Notoginseng, Polygonum runcinatum var. sinense Hemsl., Pyrola rotundifolia ssp.chinensis.Source: belong to for Compositae Herba Senecionis Chrysanthemoidis
Plant soil Radix Notoginseng Gynura segetum (Lour.) Merr., with root or all herbal medicine.Autumn and winter uproot, remove residual stem, fibrous root and
Earth dries.Xia Qiucai herb, cleans, using fresh herb or dry.Nature and flavor: hardship sweet, micro-, temperature.Cure mainly: dissipating blood stasis stops blooding, removing toxic substances and promoting subsidence of swelling.
Ganoderma: another name: Ganoderma lucidum seu Japonicum, Ganoderma, Ganoderma Lucidum.Source: this product is On Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Ganoderma
The dry son of lucidum (Leyss.ex Fr.) Karst. or Ganoderma Ganoderma sinense Zhao, Xu et Zhang is real
Body.The whole year gathers, and removes impurity, wipes out the lower end stem with rotten wood, silt or culture matrix, dry in the shade or 40～50 DEG C of bakings
Dry.Nature and flavor: sweet are flat.Gui Jing: GUIXIN, lung, liver, kidney channel.Cure mainly: invigorating QI and tranquilization, relieving cough and asthma.For dizziness sleeplessness, cardiopalmus gas
Short, asthenia cough with asthma.
Radix Et Caulis Acanthopanacis Senticosi: source: this product is Araliaceae Radix Et Caulis Acanthopanacis Senticosi Acanthopanax senticosus (Rupr.et
Maxim.) being dried of Harms, root and rhizome or stem.Spring, season in autumn two gather, cleaning, drying.Nature and flavor: hardship pungent, micro-, temperature.Gui Jing:
Return spleen, kidney, heart channel.Cure mainly: replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.For deficiency of spleen-YANG and kidneyYANG, body void is weak, inappetence, soreness of waist and knee joint,
Insomnia and dreamful sleep.
Fructus Alpiniae Oxyphyllae: another name: Fructus Alpiniae Oxyphyllae is sub, pluck son.Source: come from " book on Chinese herbal medicine must be joined ".Source: medical material Ji Yuan: plant for Zingiberaceae
The fruit of thing Fructus Alpiniae Oxyphyllae.Latin plant animal mineral name: Alpinia oxyphylla Miq. gathers and stores: 2-3 after field planting,
In the 6-7 month, when fruit be light brown, White flesh comes off, sarcocarp band is sweet, seed is pungent time, select fine day to be cut by fruit ear, remove
Fruit stem, dries or dries.Pluck when between the 5-6 month fruit is brown, White flesh reduces, remove fruit stem, dry.Nature and flavor: acrid in the mouth；
Warm in nature.Gui Jing: spleen；Kidney channel.Cure mainly: warming spleen and stopping diarrha take the photograph saliva；Warming the kidney reducing urination controlling nocturnal emission with astringent drugs.Main Deficiency and coldness of spleen and stomach；Vomiting；Have loose bowels；In abdomen cold
Educate；The many salivas of mouth；Enuresis due to deficiency of the kidney；Frequent micturition；Seminal emission；Nebulousurine.
Radix Cudraniae: another name: sesame, golden cicada ejection, HUANGLONG ejection, lead a cow into stone, Flos Wikstroemiae Nutantis, Radix Cudraniae, mountain Fructus Litchi, thousandweight
Skin.Source: Moraceae three-bristle cudrania platymiscium cudrania cochinchinensis Cudrania cochin chinensis (Lour.) Kudo et Masam., enters with root
Medicine.The whole year can adopt, and clean section is dried.Congener Zhe Shu (Ci Sang) Cudrania tricuspidata (Carr.) Bur..
Effect is roughly the same with front kind.Nature and flavor: micro-hardship are flat.Cure mainly: relieving cough and resolving phlegm, expelling wind and removing dampness, eliminating stasis to stop pain.For pulmonary tuberculosis, yellow
Subcutaneous ulcer type hepatitis, hepatosplenomegaly, taste-blindness rate, rheumatic lumbago and scelalgia；Fracture, traumatic injury are controlled in external.
Herba Hedyotis scabridae: another name: to sitting silk ball on leaf, leaf, four official report pass, Herba Alternantherae sessilis, bone leaves.Source: Rubiaceae plants of Hedyotis
Meropodium rough Auricled Hedyotis Herb Hedyotis uncinella Hook.et Arn.Var.scabrida [Oldenlandia uncinella
(Hook.et Arn.) O.Ktunze var.scabrida (Franch.) Hand.-Mazz.], with all herbal medicine.The whole year can adopt,
Clean and dry.Nature and flavor: sweet, pungent are cool.Cure mainly: expelling wind and removing dampness, spleen invigorating removing food stagnancy, heat-clearing and toxic substances removing.For rheumatic arthritis, children's's infantile malnutrition
Long-pending, chronic diarrhea, dysentery, ulcerative gingivitis；Skin pruritus, conjunctivitis are controlled in external.
Radix Codonopsis: another name: east party, platform party, the Lushui River party, mouth party.Source: this product is Campanulaceae Radix Codonopsis Codonopsis
Pilosula (Franch.) Nannf., element flower Radix Codonopsis (RADIX CODONOPSIS PILOSULAE from Northwest of China) Codonopsis pilosula Nannf.var.modesta
(Nannf.) L.T.Shen or the dry root of radix codonpsis tangshen Codonopsis tangshen Oliv..Autumn excavates, and cleans, dries.
Nature and flavor: sweet are flat.Gui Jing: return spleen, lung meridian.Cure mainly: invigorating the spleen and replenishing QI, strengthening spleen and tonifying lung.For deficiency of the spleen and lung, cardiopalmus of breathing hard, lack of appetite is just
Half congealed, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
The Radix Astragali: sweet, tepor；Return lung, spleen, liver, kidney channel.Essentials of Matea Medica: " lossless energy is sent out, and has antiperspirant for the Radix Astragali, life consolidating superficial resistance
Can be only；Process with invigorating middle warmer, benefit vigour, strong taste.Hemopoietic, granulation promoting, evacuation of pus expelling the toxic substance from the body with tonic, carbuncle sore panacea.Variola does not rises, and yang deficiency is suitable without hot person
It." " book on Chinese herbal medicine justice ": " all middle gas is depressed, and spleen soil is weak, and the clearing heat in QI system person of sinking is the most suitable for the Radix Astragali, soil, replenishing vital QI with drugs of warm nature taste in tonification.Its
Skin goes directly the skin table muscle of people, and solid protection defends sun, and substantial table divides, and is its speciality, so all diseases of exterior deficiency, god's agent the most." function consolidating superficial resistance
Arresting sweating, inducing diuresis to remove edema, holds in the palm skin ulcer evacuation of pus, regulating fluid apssage.The Radix Astragali makes contractile ability strengthen, and can improve the blood circulation of whole body,
Can coronary artery dilator, Renal vascular and Rhizoma Bistortae peripheral vessel, make cutaneous circulation vigorous；The nonspecific immunity of body can be improved
Power, protects the liver and drops hypoglycemic effect, and staphylococcus, blood dissolubility streptococcus, Diplococcus pneumoniae, dysentery bacterium etc. are had suppression
Effect.The Radix Astragali can appreciable impact splenocyte Information Conduction, it is achieved immunoregulation effect.Can be used for hypertension, ischemic
Heart disease, acute glomerulonephritis, gastric ulcer, psoriasis, diabetes, osteoporosis.
Embodiment is below used to describe embodiments of the present invention in detail, whereby to the present invention how application technology means
Solve technical problem, and the process that realizes reaching technique effect can fully understand and implement according to this.
Embodiment 1 medicated premix
Take Herba Hedyotis scabridae 8 weight portion, Fructus artocarpi lingnanensis 15 weight portion, Lignum Poria 20 weight portion, Radix Codonopsis 4 weight portion, wing handle knotweed 14 weight
Amount part, Fructus Alpiniae Oxyphyllae 15 weight portion, leaf Radix Notoginseng 13 weight portion, amur foxtail 20 weight portion, the Radix Astragali 7 weight portion, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 25 weight portion,
Ganoderma 17 weight portion, Folium Lauri nobilis 32 weight portion, Radix Cudraniae 16 weight portion, Cortex Cinnamomi 25 weight portion, Corm Eleocharitis 13 weight portion, Radix Et Caulis Acanthopanacis Senticosi 25
Weight portion and Herba Cirsii linearis 19 weight portion.
Preparation method comprises the following steps:
The first step, is mixed in proportion described each raw material, and adding relative to the determining alcohol of mixture quality 2～4 times is 85
～the ethanol of 95%, it is heated to reflux 1～3 hour, extracts, filter and obtain the first extracting solution；Filter the medicinal residues obtained and add phase
For described medicinal residues quality 1～the ethanol that determining alcohol is 85～95% of 2 times, it is heated to reflux 1～3 hour, extracts, filter and obtain
Second extracting solution；First extracting solution and the second extracting solution being merged, concentrating under reduced pressure removes alcohol solvent, is dried, it is thus achieved that dry cream；
Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, sieves, obtain
Obtain 300 mesh～the micropowders of 400 mesh, it is thus achieved that medicated premix powder.
Embodiment 2 feedstuff
Embodiments provide a kind of carp kidney cell mixed feed containing defat krill meal, each raw material in feedstuff
Parts by weight are: bean cake 200 weight portion, cottonseed meal 150 weight portion, flour 120 weight portion, corn DDGS 100 weight portion, Semen Allii Tuberosi
The dregs of rice 130 weight portion, garlicin 9 weight portion, maize germ cake 110 weight portion, Testa oryzae 20 weight portion, fish flour 40 weight portion, defat
Krill meal 40 weight portion and duck oil 21 weight portions；
Its preparation method comprises the following steps:
(1) destruction step: weigh bean cake, cottonseed meal, corn DDGS, rapeseed meal, maize germ cake, rice by ratio of weight and the number of copies
Bran, puts into pulverizer and carries out Crushing of Ultrafine, crosses 2.0mm sieve after pulverizing；
(2) batching step: weigh flour, garlicin, fish flour, defat krill meal and duck oil and medicine according to ratio of weight and number
Additive, pulverizes, with step (1), the fine powder obtained and mixes, put into mixer, and mix homogeneously, incorporation time is 40s；
(3) granulation step: putting into granulator and pelletize, pelleting temperature is 85 DEG C so that it is gelatinization degree reaches more than 90%.
Embodiment 3 feedstuff
Embodiments provide a kind of carp kidney cell mixed feed containing defat krill meal, each raw material in feedstuff
Parts by weight are: bean cake 200 weight portion, cottonseed meal 150 weight portion, flour 120 weight portion, corn DDGS 100 weight portion, Semen Allii Tuberosi
The dregs of rice 130 weight portion, garlicin 9 weight portion, maize germ cake 110 weight portion, Testa oryzae 20 weight portion, fish flour 40 weight portion, defat
Krill meal 40 weight portion, duck oil 21 weight portions and medicated premix 37 weight portion；Wherein medicated premix is the medicine of embodiment 1
Additive powder.
Its preparation method comprises the following steps:
(1) destruction step: weigh bean cake, cottonseed meal, corn DDGS, rapeseed meal, maize germ cake, rice by ratio of weight and the number of copies
Bran, puts into pulverizer and carries out Crushing of Ultrafine, crosses 2.0mm sieve after pulverizing；
(2) batching step: weigh flour, garlicin, fish flour, defat krill meal and duck oil and medicine according to ratio of weight and number
Additive, pulverizes, with step (1), the fine powder obtained and mixes, put into mixer, and mix homogeneously, incorporation time is 50s；
(3) granulation step: putting into granulator and pelletize, pelleting temperature is 85 DEG C so that it is gelatinization degree reaches more than 90%.
The toxicity test of medicated premix:
1, trial drug
Choose Herba Hedyotis scabridae 8g, Fructus artocarpi lingnanensis 15g, Lignum Poria 20g, Radix Codonopsis 4g, wing handle knotweed 14g, Fructus Alpiniae Oxyphyllae 15g, leaf Radix Notoginseng
13g, amur foxtail 20g, Radix Astragali 7g, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 25g, Ganoderma 17g, Folium Lauri nobilis 32g, Radix Cudraniae 16g, Cortex Cinnamomi 25g, Corm Eleocharitis 13g, thorn
Slender acanthopanax 25g and Herba Cirsii linearis 19g mixing, is ground into powder；Powder will be obtained and add immersion 25 hours in 140g cold water, decoct with slow fire
Boiling, decocting time is 1.5 hours, decoction liquor is filtered, it is thus achieved that the first filtrate, collects filtering residue；The filtering residue obtained will be filtered again
Add in 140g cold water, with slow fire boiling 3 times, decoct 1 hour every time, filter and merge filtrate, it is thus achieved that the second filtrate；Merge
Twice filtrate, concentrating under reduced pressure removes part water, it is thus achieved that decoction, the crude drug concentration of decoction is 3g/ml.
2, test method: select SD rat, gives the medicine of the present invention of variable concentrations (18.0,6.0,2.g crude drug/kg)
The decoction of additive, every day gavage once, continuous 90 days, last be administered latter 24 hours respectively group live and kill 1/2 animal (male and female half and half),
Remaining 1/2 animal lives after continuing to observe 2 weeks and kills.The outward appearance of animal, general behavior, food ration, body weight change is observed during test,
It is administered latter 90 days and drug withdrawal carries out hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood biochemical for 2 weeks
(AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology etc. refer to
Mark checks.Result of the test shows: the medicated premix of the present invention is good at high, medium and low dosage treated animal general state, outward appearance body
Levy, behavioral activity, food-intake and body weight increase change the most without exception；Three dosage groups and matched group hematological examination, blood life
Chemistry, urine biochemical analysis all between normal range, group without significant difference；Each group main organs histopathological examination has no bright
Aobvious abnormal.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively the 180 of clinical medicine dose, 60,
20 times, according to the Chinese medicine preparation of the result of the test present invention at high, medium and low three dosage (18.0,6.0,2.g crude drug/kg) continuously
Rat is had no significant effect by administration in 90 days, and without clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no retardance
Toxic reaction, the dose safety of the pharmaceutical preparation clinical practice of the prompting present invention is higher.
Contrast test
900 urosome weight 10g-40g carp kidney cell are chosen, from above-mentioned carp kidney cell from carp culture field, Binzhou, Shandong Province
Randomly selecting 600 tail carp kidney cell and be divided into embodiment 1 group, embodiment 2 groups and matched group, often organize 200 tails, often group sets 5 repetitions,
Each repetition 40 tail fish；Embodiment 1 group, embodiment 2 groups and matched group use the feedstuff of the embodiment of the present invention 2, embodiment 3 respectively
Feedstuff and conventional feed feed carp kidney cell, management is supported temporarily and is tamed for 2 weeks routinely, and during domestication, often group is according to above-mentioned
Throw something and feed corresponding feedstuff；Manually be satiated with food every day throw something and feed four times (8:00,11:00,14:00,17:00), puts into 10 feedstuffs every time,
Treating that fry robs food complete, continue to put into 10, circulate successively, until fry does not robs food at the water surface, then stopping throwing something and feeding, every cylinder is thrown something and fed
One minute time；Carry out daily Cyprinus carpio rate of body weight gain, specific growth rate, feedstuff feeding amount, feed coefficient, survival rate and across back, tail
Handle thickness, intestinal body ratio, height, coefficient of condition, dirty body than the result of the test of regulating liver-QI body ratio respectively such as following table:
Table 1 is the nutritional labeling of each experimental group feedstuff:
Knowable to the data of table 1: compared with matched group, crude protein, thick fat in the feedstuff that embodiment of the present invention 1-2 group uses
Fat, ash, the nutritional labeling of Ca, P are all higher than matched group, and wherein, in the feedstuff that embodiment of the present invention 1-2 group uses, Ca/P is less than
Matched group, therefore, the feedstuff of the present invention disclosure satisfy that the nutritional need of carp kidney cell.
Table 2 is the impact on carp growth performance of each experimental group feedstuff:
Note: normal data, colleague's shoulder note same letter represents that difference is not notable (P ＞ 0.05), and shoulder notes different letter person's table
Show significant difference (P ＜ 0.05).
Knowable to the data of table 2: compared with matched group, the carp kidney cell of embodiment of the present invention 1-2 group does not occur sick
Or death condition, survival rate is 100%, wherein, and end counterpoise, survival rate, rate of body weight gain, specific growth rate and feedstuff feeding eventually
Measure and exceed matched group 0.95g and 1.07g respectively, 7% and 7%, 10.19% and 30.93%, 0.06%/d and 0.16%/d,
79.4g and 158.7g；Feed coefficient is substantially less than matched group.
Table 3 each experimental group feedstuff is to carp kidney cell body index analysis:
Note: normal data, colleague's shoulder note same letter represents that difference is not notable (P ＞ 0.05), and shoulder notes different letter person's table
Show significant difference (P ＜ 0.05).
Knowable to the data of table 3: compared with matched group, the across back of carp kidney cell feedstuff of embodiment of the present invention 1-2 group, tail
Handle thickness, intestinal body ratio are apparently higher than matched group, and height, coefficient of condition, dirty body are below matched group than regulating liver-QI body ratio.
Understand in sum: the carp kidney cell using the mixed feed of embodiment of the present invention 1-2 group to feed can expire Cyprinus carpio
The nutritional need of juvenile fish, improves survival rate, rate of body weight gain and specific growth rate, significantly reduces feed coefficient regulating liver-QI body ratio, the suitableeest
Nutritional need for 10g-40g carp kidney cell.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and
Within principle, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.
Claims (9)
1. the carp kidney cell mixed feed containing defat krill meal, it is characterised in that described mixed feed includes following raw material:
Bean cake, cottonseed meal, flour, corn DDGS, rapeseed meal, garlicin, maize germ cake, Testa oryzae, fish flour, defat krill meal and duck
Oil.
Carp kidney cell mixed feed containing defat krill meal the most according to claim 1, it is characterised in that described cooperation is raised
Material is made up of the raw material of following parts by weight: bean cake 100-300 weight portion, cottonseed meal 70-200 weight portion, flour 90-160 weight
Amount part, corn DDGS 50-150 weight portion, rapeseed meal 80-220 weight portion, garlicin 6-12 weight portion, maize germ cake 70-
140 weight portions, Testa oryzae 10-40 weight portion, fish flour 20-100 weight portion, defat krill meal 0-80 weight portion and duck oil 15-25 weight
Amount part.
Carp kidney cell mixed feed containing defat krill meal the most according to claim 1 and 2, it is characterised in that described in join
Close feedstuff to be made up of the raw material of following parts by weight: bean cake 200 weight portion, cottonseed meal 150 weight portion, flour 120 weight portion, jade
Miho Dockyard DGS100 weight portion, rapeseed meal 130 weight portion, garlicin 9 weight portion, maize germ cake 110 weight portion, Testa oryzae 20 weight
Part, fish flour 40 weight portion, defat krill meal 40 weight portion and duck oil 21 weight portions.
4. according to the carp kidney cell mixed feed containing defat krill meal described in any one of claim 1-3, it is characterised in that institute
Stating mixed feed and also include medicated premix, described mixed feed is made up of the raw material material of following parts by weight: bean cake 100-300
Weight portion, cottonseed meal 70-200 weight portion, flour 90-160 weight portion, corn DDGS 50-150 weight portion, rapeseed meal 80-220
Weight portion, garlicin 6-12 weight portion, maize germ cake 70-140 weight portion, Testa oryzae 10-40 weight portion, fish flour 20-100 weight
Part, defat krill meal 0-80 weight portion, duck oil 15-25 weight portion and medicated premix 20-50 weight portion.
5. according to the carp kidney cell mixed feed containing defat krill meal described in any one of claim 1-4, it is characterised in that institute
State additive for fodder to be made up of the raw material of following parts by weight: bean cake 200 weight portion, cottonseed meal 150 weight portion, flour
120 weight portions, corn DDGS 100 weight portion, rapeseed meal 130 weight portion, garlicin 9 weight portion, maize germ cake 110 weight
Part, Testa oryzae 20 weight portion, fish flour 40 weight portion, defat krill meal 40 weight portion, duck oil 21 weight portions and medicated premix 37 weight
Amount part.
6. according to the carp kidney cell mixed feed containing defat krill meal described in any one of claim 1-5, it is characterised in that institute
State medicated premix to be made up of the raw material of following parts by weight: Herba Hedyotis scabridae 6-12 weight portion, Fructus artocarpi lingnanensis 9-18 weight portion, Lignum Poria
12-22 weight portion, Radix Codonopsis 2-8 weight portion, wing handle knotweed 7-16 weight portion, Fructus Alpiniae Oxyphyllae 10-22 weight portion, leaf Radix Notoginseng 8-15 weight
Part, amur foxtail 11-21 weight portion, Radix Astragali 5-12 weight portion, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 13-26 weight portion, Ganoderma 10-22 weight portion, Folium Lauri nobilis
12-34 weight portion, Radix Cudraniae 9-17 weight portion, Cortex Cinnamomi 15-35 weight portion, Corm Eleocharitis 9-14 weight portion, Radix Et Caulis Acanthopanacis Senticosi 13-27 weight portion
With Herba Cirsii linearis 15-25 weight portion.
7. according to the carp kidney cell mixed feed containing defat krill meal described in any one of claim 1-6, it is characterised in that institute
State medicated premix to be made up of the raw material of following parts by weight: Herba Hedyotis scabridae 8 weight portion, Fructus artocarpi lingnanensis 15 weight portion, Lignum Poria 20 weight
Amount part, Radix Codonopsis 4 weight portion, wing handle knotweed 14 weight portion, Fructus Alpiniae Oxyphyllae 15 weight portion, leaf Radix Notoginseng 13 weight portion, amur foxtail 20 weight portion,
The Radix Astragali 7 weight portion, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 25 weight portion, Ganoderma 17 weight portion, Folium Lauri nobilis 32 weight portion, Radix Cudraniae 16 weight portion, Cortex Cinnamomi 25
Weight portion, Corm Eleocharitis 13 weight portion, Radix Et Caulis Acanthopanacis Senticosi 25 weight portion and Herba Cirsii linearis 19 weight portion.
8. according to the carp kidney cell mixed feed containing defat krill meal described in any one of claim 1-7, it is characterised in that institute
The preparation method stating medicated premix comprises the following steps:
The first step, is mixed in proportion described each raw material, and adding relative to the determining alcohol of mixture quality 2～4 times is 85～95%
Ethanol, be heated to reflux 1～3 hour, extract, filter obtain the first extracting solution；Filter the medicinal residues obtained to add relative to institute
State the ethanol that determining alcohol is 85～95% of medicinal residues quality 1～2 times, be heated to reflux 1～3 hour, extract, filter acquisition second and carry
Take liquid；First extracting solution and the second extracting solution being merged, concentrating under reduced pressure removes alcohol solvent, is dried, it is thus achieved that dry cream；
Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, sieves, it is thus achieved that 300
Mesh～the micropowders of 400 mesh, it is thus achieved that medicated premix powder.
9. according to the preparation method of the carp kidney cell mixed feed containing defat krill meal described in any one of claim 1-8, its
Being characterised by, described preparation method comprises the following steps:
(1) destruction step: weigh bean cake, cottonseed meal, corn DDGS, rapeseed meal, maize germ cake, Testa oryzae by ratio of weight and the number of copies,
Put into pulverizer and carry out Crushing of Ultrafine, after pulverizing, cross 2.0mm sieve；
(2) batching step: weigh flour, garlicin, fish flour, defat krill meal and duck oil according to ratio of weight and number and medicine adds
Agent, pulverizes, with step (1), the fine powder obtained and mixes, put into mixer, and mix homogeneously, incorporation time is 30-60s；
(3) granulation step: putting into granulator and pelletize, pelleting temperature is 85 DEG C so that it is gelatinization degree reaches more than 90%.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610626335.3A CN106234841A (en) | 2016-08-02 | 2016-08-02 | A kind of carp kidney cell mixed feed containing defat krill meal and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610626335.3A CN106234841A (en) | 2016-08-02 | 2016-08-02 | A kind of carp kidney cell mixed feed containing defat krill meal and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103238738A (en) * | 2012-02-13 | 2013-08-14 | 周生会 | Juvenile carp feed |
| CN103652479A (en) * | 2013-12-07 | 2014-03-26 | 济南凯因生物科技有限公司 | Carp feed |
| CN104286594A (en) * | 2014-11-11 | 2015-01-21 | 济南凯因生物科技有限公司 | Juvenile carp feed |
-
2016
- 2016-08-02 CN CN201610626335.3A patent/CN106234841A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103238738A (en) * | 2012-02-13 | 2013-08-14 | 周生会 | Juvenile carp feed |
| CN103652479A (en) * | 2013-12-07 | 2014-03-26 | 济南凯因生物科技有限公司 | Carp feed |
| CN104286594A (en) * | 2014-11-11 | 2015-01-21 | 济南凯因生物科技有限公司 | Juvenile carp feed |
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