CN106214821A - A kind of clinical laboratory disinfection solution - Google Patents

A kind of clinical laboratory disinfection solution Download PDF

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Publication number
CN106214821A
CN106214821A CN201610776929.2A CN201610776929A CN106214821A CN 106214821 A CN106214821 A CN 106214821A CN 201610776929 A CN201610776929 A CN 201610776929A CN 106214821 A CN106214821 A CN 106214821A
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parts
herba
radix
disinfection solution
root
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宋克玉
种荣华
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
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  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
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  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
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  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a kind of clinical laboratory disinfection solution, it is made up of the raw material of following weight proportioning: Armillaria mella tabescens (Scop.ex Fr.) Sing. 5 15 parts, Stachys palustris L. 10 15 parts, Radix araliae armatae 58 parts, Corydalis gigantea et Meer. 35 parts, Radix Gossypii 27 parts, Herba Pileae Scriptae 5 10 parts, root of Herba Cichorii 5 10 parts, 10 15 parts of Paulownia bark, Herba leucadis zeylanicae 8 13 parts, chitosan quaternary ammonium salt 10 15 parts, polyvinyl alcohol 10 20 parts.The disinfection solution of the present invention uses the macromolecular material of natural Chinese medicines raw material and good biocompatibility to make, and has both had good sterilizing antiinflammatory action, can effectively facilitate again wound healing, non-stimulated to wound, safe without toxic side effect.

Description

A kind of clinical laboratory disinfection solution
Technical field
The invention belongs to sterilizing technical field, be specifically related to a kind of clinical laboratory disinfection solution.
Background technology
The section office that clinical laboratory chemically examines as hospital inspection, often extract specimen to some traumatic patients and chemically examine, make Sterilizing medicine such as iodine tincture, ethanol, povidone iodine etc. be mostly made up of chemicals, the chemicals of this kind to human body hinder Mouth and skin have serious zest, are unfavorable for the healing of wound, and have even can cause serious anaphylaxis, if sterilization Sterilize the most thorough, it is easy to fester a wound.
Summary of the invention
It is an object of the invention to provide that a kind of disinfection effect is good, nonirritant, be beneficial to wound healing, safety non-toxic Clinical laboratory's disinfection solution of side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of clinical laboratory disinfection solution, by following The raw material of weight proportion is made: Armillaria mella tabescens (Scop.ex Fr.) Sing. 5-15 part, Stachys palustris L. 10-15 part, Radix araliae armatae 5-8 part, Corydalis gigantea et Meer. 3-5 part, Radix Gossypii 2-7 part, Herba Pileae Scriptae 5-10 part, root of Herba Cichorii 5-10 part, Paulownia bark 10-15 part, Herba leucadis zeylanicae 8-13 part, chitosan quaternary ammonium salt 10- 15 parts, polyvinyl alcohol 10-20 part.
Preferably, a kind of clinical laboratory disinfection solution, it is made up of the raw material of following weight proportioning: Armillaria mella tabescens (Scop.ex Fr.) Sing. 10 parts, light leaf Herba Stachydis Japonicae 10 parts, Radix araliae armatae 5 parts, Corydalis gigantea et Meer. 5 parts, Radix Gossypii 7 parts, Herba Pileae Scriptae 5 parts, root of Herba Cichorii 8 parts, 10 parts of Paulownia bark, honeycomb Grass 10 parts, chitosan quaternary ammonium salt 13 parts, polyvinyl alcohol 15 parts.
The preparation method of above-mentioned disinfection solution is as follows: by Armillaria mella tabescens (Scop.ex Fr.) Sing., Stachys palustris L., Radix araliae armatae, Corydalis gigantea et Meer., Radix Gossypii, nine Joint tea, root of Herba Cichorii, Paulownia bark, Herba leucadis zeylanicae boiling 45 minutes, filter, and taking liquid, while hot by chitosan quaternary ammonium salt, poly-second Enol adds, and dissolving stirs, sterilizing subpackage.
Armillaria mella tabescens (Scop.ex Fr.) Sing., for Bai Mo section fungus luminescence armillariella tabescens filament, bitter, cold in nature, return liver, gallbladder meridian, heat-clearing and toxic substances removing.Main acute and chronic Cholecystitis;Biliary tract infection;Hepatitis;Appendicitis;Otitis media.Containing armillariella tabescens A and B, gram positive bacteria and fungus are had antibacterial Effect.
Stachys palustris L., for root or the herb of labiate Stachys palustris L., removing heat-phlegm, anti-inflammation.Control cough due to pathogenic wind-heat, Laryngopharynx swelling and pain, pertussis, dysentery, herpes zoster.
Radix araliae armatae, for root, root bark or the branch and leaf of Araliaceae Herba Damnacanthi wood, bitter in the mouth, pungent, property is put down, dissipating blood stasis;Dispel the wind;Profit Wet;Removing toxic substances.Main traumatic injury;Rheumatic arthralgia;Jaundice due to damp-heat;Stranguria with turbid discharge;Edema;Dysentery;Leucorrhea;Gastric abscess;Headache;Swelling throat Bitterly;Acute mastitis;Innominate toxic swelling;Scrofula carbuncle." Guangxi practicality Chinese herbal medicine newly selects ": dissipating blood stasis for subsidence of swelling, antibacterial pain relieving.Control traumatic injury, carbuncle, Furuncle, hepatitis, nephritis, prostatitis, acute arthritis, gastropathy, diarrhoea, dysentery, leucorrhea.
Corydalis gigantea et Meer., for the herb of bloodroot Corydalis gigantea et Meer., hardship, trembles with fear, returns lung, the heart, Liver Channel, antalgic and sedative;Anti-inflammation. Main various pain.
Radix Gossypii, for root or the root bark of Malvaceae plant cotton etc., sweet in the mouth, warm in nature, return lung, spleen, Liver Channel, relieving cough and asthma; Inducing menstruation to relieve menalgia.Main cough;Asthma;Have through uncomfortable;Metrorrhagia.Decoct and various extract thereof to streptococcus pneumoniae, Hemolytic streptococcus, Micrococcus catarrhalis, hemophilus influenza etc. have certain inhibitory action.
Herba Pileae Scriptae, for the branch and leaf of Chloranthaceae plant synthetism chu lan tree, pungent, flat, anti-inflammation, expelling wind and removing dampness, only invigorate blood circulation Bitterly.Control pneumonia, acute appendicitis, acute gastroenteritis, bacillary dysentery, rheumatalgia, traumatic injury, fracture.
Root of Herba Cichorii, for the root of feverfew Herba Cichorii, mildly bitter flavor, cool in nature, heat clearing away;Stomach invigorating.Main dyspepsia;Born of the same parents' abdominal distention is vexed.
Paulownia bark, for goatweed Paulownia or the bark of royal paulownia, bitter in the mouth, cold in nature, expelling wind and removing dampness;Subduing swelling and detoxicating. Main air damp-heat arthralgia;Discharging fresh blood stool;Wound swells and ache;Fracture.Relatively strong to staphylococcus aureus, bacillus subtilis effect, to karr this Uncle's gold yeast takes second place, more weak to escherichia coli.
Herba leucadis zeylanicae, for labiate crape face grass and the herb of honeybee fruit grass, acrid in the mouth, bitter, property is put down, removing toxic substances;Cough-relieving;Improving eyesight; Stimulate the menstrual flow.Main flu;Headache;Asthma;Pertussis;Laryngopharynx swelling and pain;Toothache;Dyspepsia;Menoxenia;Amenorrhea;Extort under false pretense blind;Honeycomb Skin ulcer.The existing bacteriostasis of Herba leucadis zeylanicae has again bactericidal action.
Chitosan quaternary ammonium salt, have good water solublity, antibiotic property, film property, cation-adsorption, moisture absorbability and moisture retentivity, The performance such as flocculability, antistatic behaviour.Its anti-microbial property is better than chitosan and other chitosan derivatives.
Polyvinyl alcohol, soluble in water, to human non-toxic, have no side effect, there is good biocompatibility, safe to the human body Macromolecule organic.
The method have the advantages that the disinfection solution of the present invention uses natural Chinese medicines raw material and bio-compatible The macromolecular material that property is good is made, and has both had good sterilizing antiinflammatory action, can effectively facilitate again wound healing, to wound Non-stimulated, safe without toxic side effect.
Detailed description of the invention
The following is the specific embodiment of the present invention, technical scheme is described further, but the present invention Protection domain is not limited to these embodiments.Every change without departing substantially from present inventive concept or equivalent replacement are included in the present invention Protection domain within.
Embodiment 1
A kind of clinical laboratory disinfection solution, is made up of the raw material of following weight proportioning: Armillaria mella tabescens (Scop.ex Fr.) Sing. 10 parts, Stachys palustris L. 10 Part, Radix araliae armatae 5 parts, Corydalis gigantea et Meer. 5 parts, Radix Gossypii 7 parts, Herba Pileae Scriptae 5 parts, root of Herba Cichorii 8 parts, 10 parts of Paulownia bark, Herba leucadis zeylanicae 10 parts, Chitosan quaternary ammonium salt 13 parts, polyvinyl alcohol 15 parts.
The preparation method of above-mentioned disinfection solution is as follows: by Armillaria mella tabescens (Scop.ex Fr.) Sing., Stachys palustris L., Radix araliae armatae, Corydalis gigantea et Meer., Radix Gossypii, nine Joint tea, root of Herba Cichorii, Paulownia bark, Herba leucadis zeylanicae boiling 45 minutes, filter, and taking liquid, while hot by chitosan quaternary ammonium salt, poly-second Enol adds, and dissolving stirs, sterilizing subpackage.
Embodiment 2
A kind of clinical laboratory disinfection solution, is made up of the raw material of following weight proportioning: Armillaria mella tabescens (Scop.ex Fr.) Sing. 5 parts, Stachys palustris L. 12 parts, Radix araliae armatae 7 parts, Corydalis gigantea et Meer. 3 parts, Radix Gossypii 5 parts, Herba Pileae Scriptae 10 parts, root of Herba Cichorii 7 parts, 12 parts of Paulownia bark, Herba leucadis zeylanicae 12 parts, shell Polysaccharide quaternary ammonium salt 10 parts, polyvinyl alcohol 20 parts.
The preparation method of above-mentioned disinfection solution is as follows: by Armillaria mella tabescens (Scop.ex Fr.) Sing., Stachys palustris L., Radix araliae armatae, Corydalis gigantea et Meer., Radix Gossypii, nine Joint tea, root of Herba Cichorii, Paulownia bark, Herba leucadis zeylanicae boiling 45 minutes, filter, and taking liquid, while hot by chitosan quaternary ammonium salt, poly-second Enol adds, and dissolving stirs, sterilizing subpackage.
Embodiment 3
A kind of clinical laboratory disinfection solution, is made up of the raw material of following weight proportioning: Armillaria mella tabescens (Scop.ex Fr.) Sing. 15 parts, Stachys palustris L. 15 Part, Radix araliae armatae 6 parts, Corydalis gigantea et Meer. 4 parts, Radix Gossypii 2 parts, Herba Pileae Scriptae 6 parts, root of Herba Cichorii 5 parts, 15 parts of Paulownia bark, Herba leucadis zeylanicae 8 parts, Chitosan quaternary ammonium salt 12 parts, polyvinyl alcohol 13 parts.
The preparation method of above-mentioned disinfection solution is as follows: by Armillaria mella tabescens (Scop.ex Fr.) Sing., Stachys palustris L., Radix araliae armatae, Corydalis gigantea et Meer., Radix Gossypii, nine Joint tea, root of Herba Cichorii, Paulownia bark, Herba leucadis zeylanicae boiling 45 minutes, filter, and taking liquid, while hot by chitosan quaternary ammonium salt, poly-second Enol adds, and dissolving stirs, sterilizing subpackage.
Embodiment 4
A kind of clinical laboratory disinfection solution, is made up of the raw material of following weight proportioning: Armillaria mella tabescens (Scop.ex Fr.) Sing. 13 parts, Stachys palustris L. 13 Part, Radix araliae armatae 8 parts, Corydalis gigantea et Meer. 5 parts, Radix Gossypii 4 parts, Herba Pileae Scriptae 8 parts, root of Herba Cichorii 10 parts, 13 parts of Paulownia bark, Herba leucadis zeylanicae 13 Part, chitosan quaternary ammonium salt 15 parts, polyvinyl alcohol 10 parts.
The preparation method of above-mentioned disinfection solution is as follows: by Armillaria mella tabescens (Scop.ex Fr.) Sing., Stachys palustris L., Radix araliae armatae, Corydalis gigantea et Meer., Radix Gossypii, nine Joint tea, root of Herba Cichorii, Paulownia bark, Herba leucadis zeylanicae boiling 45 minutes, filter, and taking liquid, while hot by chitosan quaternary ammonium salt, poly-second Enol adds, and dissolving stirs, sterilizing subpackage.
Clinical carry out 200 example traumatic patients uses observation, is randomly divided into two groups, experimental group 100 example, matched group 100 example, Two groups there was no significant difference.
Experimental group uses the disinfection solution of the present invention to process patient wound, and matched group uses povidone iodine to hinder patient Mouth processes.
Comparative result:
Experimental group patient is all without anaphylaxis, and wound bactericidal antiphlogistic is thorough, without suppurating.
Matched group has 36 people the most thoroughly to occur that skin allergy occur in wound suppuration, 18 people because of sterilization.
Additionally the wound healing time of experimental group is significantly shorter than the wound healing time of matched group.

Claims (3)

1. clinical laboratory's disinfection solution, it is characterised in that be made up of the raw material of following weight proportioning: Armillaria mella tabescens (Scop.ex Fr.) Sing. 5-15 part, Stachys palustris L. 10-15 part, Radix araliae armatae 5-8 part, Corydalis gigantea et Meer. 3-5 part, Radix Gossypii 2-7 part, Herba Pileae Scriptae 5-10 part, root of Herba Cichorii 5-10 Part, Paulownia bark 10-15 part, Herba leucadis zeylanicae 8-13 part, chitosan quaternary ammonium salt 10-15 part, polyvinyl alcohol 10-20 part.
2. clinical laboratory as claimed in claim 1 disinfection solution, it is characterised in that by the raw material system of following weight proportioning Become: Armillaria mella tabescens (Scop.ex Fr.) Sing. 10 parts, Stachys palustris L. 10 parts, Radix araliae armatae 5 parts, Corydalis gigantea et Meer. 5 parts, Radix Gossypii 7 parts, Herba Pileae Scriptae 5 parts, root of Herba Cichorii 8 parts, bubble Tung oil tree skin 10 parts, Herba leucadis zeylanicae 10 parts, chitosan quaternary ammonium salt 13 parts, polyvinyl alcohol 15 parts.
3. clinical laboratory as claimed in claim 1 or 2 disinfection solution, it is characterised in that its preparation method is as follows: by bright Bacterium, Stachys palustris L., Radix araliae armatae, Corydalis gigantea et Meer., Radix Gossypii, Herba Pileae Scriptae, root of Herba Cichorii, Paulownia bark, Herba leucadis zeylanicae boiling 45 minutes, Filtering, taking liquid, chitosan quaternary ammonium salt, polyvinyl alcohol are added while hot, dissolving stirs, sterilizing subpackage.
CN201610776929.2A 2016-08-31 2016-08-31 A kind of clinical laboratory disinfection solution Pending CN106214821A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106577849A (en) * 2016-12-29 2017-04-26 周宪伟 Pure traditional Chinese medicine sterilization and disinfection fluid for clinical laboratory

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435604A (en) * 2014-11-28 2015-03-25 成都顺发消洗科技有限公司 Preparation method of Chinese herbal medicine skin mucosa disinfectant
CN105497414A (en) * 2015-12-22 2016-04-20 孟伟 Sterilization and disinfection liquid for clinical laboratory medical staff
CN105920423A (en) * 2016-06-28 2016-09-07 李秀萍 Sterilization disinfectant applied to clinical laboratories and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435604A (en) * 2014-11-28 2015-03-25 成都顺发消洗科技有限公司 Preparation method of Chinese herbal medicine skin mucosa disinfectant
CN105497414A (en) * 2015-12-22 2016-04-20 孟伟 Sterilization and disinfection liquid for clinical laboratory medical staff
CN105920423A (en) * 2016-06-28 2016-09-07 李秀萍 Sterilization disinfectant applied to clinical laboratories and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106577849A (en) * 2016-12-29 2017-04-26 周宪伟 Pure traditional Chinese medicine sterilization and disinfection fluid for clinical laboratory

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Application publication date: 20161214