CN106259526A - A kind of checked operation equipment cleaning liquid and preparation method - Google Patents

A kind of checked operation equipment cleaning liquid and preparation method Download PDF

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CN106259526A
CN106259526A CN201610562681.XA CN201610562681A CN106259526A CN 106259526 A CN106259526 A CN 106259526A CN 201610562681 A CN201610562681 A CN 201610562681A CN 106259526 A CN106259526 A CN 106259526A
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parts
herba
radix
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cleaning solution
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周红岩
杨莉
张红岩
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/40—Liliopsida [monocotyledons]
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/40—Products in which the composition is not well defined
    • C11D7/44—Vegetable products

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Abstract

The present invention relates to a kind of checked operation equipment cleaning liquid and preparation method, belong to the field of Chinese medicines；The raw material of cleaning solution effective ingredient of the present invention consists of: Herba Erigerontis Annui, Cortex Fraxini, Herba potentillae fulgentis, Herba Schizonepetae, Fructus Forsythiae, emblic leafflower fruit, Radix et Caulis Opuntiae Dillenii, Herba Alternantherae sessilis, Receptaculum Nelumbinis, Radix Polygoni Ciliinerve, Herba Portulacae, Herba Pteridis Semipinnatae, Cacumen Platycladi, Radix Ardisiae Crenatae, Pseudobulbus Bletillae (Rhizoma Bletillae) and Herba Taraxaci；Selected by cleaning solution of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine is theoretical, there is the advantages such as sterilizing ability is strong, reagentia is fast, stability is strong, and it is non-stimulated to human body skin, by rear noresidue, soluble in water, safe without toxic side effect, can be widely applied to the cleaning of clinical laboratory's operation equipment, improve the work efficiency of clinical laboratory personnel, it is ensured that the accuracy rate of assay.

Description

A kind of checked operation equipment cleaning liquid and preparation method
Technical field
The present invention relates to the field of Chinese medicines, particularly to a kind of checked operation equipment cleaning liquid and preparation method.
Background technology
Medical inspection section carries the task of medical test, it is necessary to assure the accuracy of inspection, so clinical laboratory should be by Antibacterial scope is preferably minimized, especially checked operation equipment, so being cleaned critically important to checked operation equipment.
Clinical laboratory personnel are to use manually to be cleaned to the clean method that checked operation equipment is conventional, occur in that new later Sterilization method, such as disinfection by ultraviolet light, microwave radiation is sterilized, the operation equipment tentatively cleaned is placed in special device Inside carry out disinfection and store, but such sterilization method exists certain defect, use special device to carry out unifying sterilization Although method can kill Most bacterial and virus, but cannot enter the bloodstain pus mark remained on inspection apparatus and secretions etc. Row is removed, and the Proteinaceous Organic substance that inspection apparatus pollutes cleans not thorough, microorganism is had protective effect, easily causes and go out Bacterium failure, takes out after sterilization and can breed bacteria again, it is impossible to ensure absolute sanitation and hygiene.
Preferably cleaning solution should possess that fungicidal spectrum is wide, sterilizing ability is strong, speed of action is fast, good stability, toxicity are low, corrode The feature such as property is little, zest is little, soluble in water, safe and cheap and easy to get to people, environmental pollution degree is low.Thus be used for checking The medicine of operation equipment must safely, effectively, have no side effect, and Chinese materia medica is as the traditional medicine of China, have effect strong, The advantage such as instant effect, lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore select a kind of cleaning solution to be used for The cleaning of checked operation equipment, is of great significance for clinical laboratory's tool.
Summary of the invention
The invention provides a kind of checked operation equipment cleaning liquid and preparation method, medical material compatibility selected by cleaning solution of the present invention Suitable, meet Chinese medicine and modern medicine is theoretical, there is the advantages such as sterilizing ability is strong, reagentia is fast, stability is strong, and to people Body skin is non-stimulated, by rear noresidue, soluble in water, safe without toxic side effect, can be widely applied to clinical laboratory's operation equipment Cleaning, improves the work efficiency of clinical laboratory personnel, it is ensured that the accuracy rate of assay.
For achieving the above object, the enforcement of technical scheme is as follows:
A kind of checked operation equipment cleaning liquid, raw material composition and the parts by weight of making described cleaning solution effective ingredient are:
Make described cleaning solution effective ingredient raw material composition and parts by weight be:
Make described cleaning solution effective ingredient raw material composition and parts by weight be:
Make described cleaning solution effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of checked operation equipment cleaning liquid, comprises the following steps that:
(1) Herba Erigerontis Annui, Radix et Caulis Opuntiae Dillenii and Herba Alternantherae sessilis are gone the removal of impurity, clean, be placed in strand juice in container, filter, obtain filtrate, standby With；
(2) Cortex Fraxini, Herba potentillae fulgentis, Herba Schizonepetae, emblic leafflower fruit, Receptaculum Nelumbinis and Radix Ardisiae Crenatae are gone the removal of impurity, clean, put in container, add 6 Times amount distilled water, soaks 4 hours, decocts 3 hours, extracts decoction liquor；Add 4 times amount distilled water, decoct 2 hours, extract and decoct Boil liquid, finally merge the decoction liquor extracted 2 times, filter, obtain filtrate, standby；
(3) Fructus Forsythiae, Herba Portulacae, Herba Pteridis Semipinnatae, Cacumen Platycladi and Herba Taraxaci are gone the removal of impurity, clean, fry with high heat in being placed in pot To burnt brown, spraying clear water, taking-up is dried, and grinds into powder in being placed in mortar, obtains the fine powder of 120 mesh, standby；
(4) Radix Polygoni Ciliinerve and Pseudobulbus Bletillae (Rhizoma Bletillae) are gone the removal of impurity, clean, section, it is placed in pot, sprays yellow wine and mix thoroughly, slow fire is fried extremely Yellow wine is sucked, and taking-up is dried, and grinds into powder in being placed in mortar, obtains the fine powder of 140 mesh, standby；
(5) 12 are added after step (1), the filtrate of step (2) gained being mixed with the fine powder of step (3), step (4) gained ～15 distilled water of times amount, stirring and dissolving uniformly after, heated and boiled 1 hour, to less than 60 DEG C, stands 1 hour, filtration, obtain filter Liquid, seals up for safekeeping filtrate fill, 121 DEG C of pressure sterilizings 30 minutes, and packaging is described checked operation equipment cleaning liquid.
The property of medicine of Chinese medicine used by the present invention is as follows:
Herba Erigerontis Annui: bitter in the mouth, cool in nature；Return stomach, large intestine channel.Heat-clearing and toxic substances removing is aid digestion.For dyspepsia, enteritis, diarrhea, pass Metachromia hepatitis, lymphadenitis, hematuria." Zhejiang conventional medical herbs among the people " carries: " help digestion, antidiarrheal, removing toxic substances, hemostasis." modern medicine grinds Studying carefully confirmation, Herba Erigerontis Annui has inhibitory action to staphylococcus aureus, shigella.
Cortex Fraxini: bitter in the mouth, puckery, cold in nature；Return liver, gallbladder, large intestine channel.Heat clearing and damp drying, astringent therapy improving eyesight.Have loose bowels for hematodiarrhoea, red in vain Leukorrhagia, conjunctival congestion and swelling pain, the raw nebula film of mesh." property of medicine opinion " carries: " main improving eyesight, goes in liver heat for a long time, and two conjunctival congestions swell pain, and lacrimation induced by wind pathogen is more than, controls Children's's fever of the body." modern medicine study confirmation, Cortex Fraxini decoct has antibacterial action.
Herba potentillae fulgentis: bitter in the mouth, puckery, cold in nature；Return spleen, large intestine channel.Heat clearing and inflammation relieving, cooling blood for hemostasis.For dysentery, enteritis stomach Bitterly, hemoptysis of pulmonary tuberculosis, epistaxis has blood in stool, traumatic hemorrhage, metrorrhagia furuncle." choosing of Simao, Yunnan Chinese herbal medicine " carries: " clearing away heat to stop bleeding, antiinflammatory Convergence.Control dysentery enteritis, stomachache spitting of blood, spit blood, traumatic hemorrhage.”
Herba Schizonepetae: acrid in the mouth, slightly warm in nature；Return lung, Liver Channel.Delivering and dispel the wind, treating blood disorders is stopped blooding.For cold, fever, headache, swelling throat Bitterly, apoplexy locked mouth, hematemesis and epistaxis, metrorrhagia of having blood in stool, puerperal blood faints, carbuncle skin ulcer scabies." detailed outline " carries: " dissipate wind heat, refresh oneself, sore-throat relieving Larynx, the skin ulcer that disappears swells.Control stiffness of the nape, black flower in mesh, and raw skin ulcer, cloudy ruined haematemesis, epistaxis hematochezia, dysentery metrorrhagia." modern medicine study card Real, Herba Schizonepetae decoct has stronger antibacterial action to staphylococcus aureus and diphtheria corynebacterium, to anthrax bacillus, group B streptococcus, Bacillus typhi, dysentery bacterium, bacillus pyocyaneus, Bacillus tuberculosis etc. all show certain inhibitory action.
Fructus Forsythiae: bitter in the mouth, cold nature；Return lung, the heart, small intestine meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle scrofula, acute mastitis is red Poison, anemopyretic cold, epidemic febrile disease from the beginning of, warm is joined the army, high hot excessive thirst, and coma sends out speckle, pyretic stranguria urine retention.Fructus Forsythiae decoct to Bacillus typhi, Salmonella paratyphi, escherichia coli, dysentery bacterium, diphtheria corynebacterium, vibrio cholera, staphylococcus, streptococcus etc. are inhibited.
Emblic leafflower fruit: bitter in the mouth, sweet, cold in nature；Return spleen, stomach warp.Acting as expectorant, cough-relieving is detoxified.For cold, fever, cough pharynx Bitterly, diphtheria, restlessness and fever with thirst.Modern medicine study confirms, emblic leafflower fruit is to staphylococcus, Bacillus typhi, Salmonella paratyphi, large intestine bar Bacterium and dysentery bacterium all have inhibitory action.
Radix et Caulis Opuntiae Dillenii: bitter in the mouth, cold in nature；GUIXIN, lung, stomach warp.Promoting flow of QI and blood, heat-clearing and toxic substances removing.For heart peratodynia, mass in the abdomen dysentery Disease, hemorrhoidal bleeding cough, lung abscess of having sore throat, acute mastitis furuncle, burn, snakebite." east, Fujian book on Chinese herbal medicine " carries: " stomach invigorating is only for energy blood stasis removing, intestinal detoxication Bitterly, nourishing, relaxing muscles and tendons and activating QI and blood in the collateral, hemostasis of curing the wound.Control hemorrhoidal hamorrhage anal fistula hematochezia, lung abscess, stomachache, traumatic injury." modern medicine study card Real, Radix et Caulis Opuntiae Dillenii is the most notable to staphylococcus aureus inhibition, and 18 resistance to penicillin systems of this bacterium are also had height Inhibitory action.
Herba Alternantherae sessilis: bitter in the mouth, cool in nature；GUIXIN, small intestine meridian.Heat clearing away, diuresis, removing toxic substances.For haematemesis of coughing, dysentery, under hemorrhoidal hamorrhage Blood, gonorrhea, swollen ulcer drug, eczema." the SHENGCAO property of medicine standby will " carries: " skin ulcer is applied in dissipating blood stasis, sterilization.”
Receptaculum Nelumbinis: bitter in the mouth, puckery, warm in nature.Repercussive, hemostasis, dry.For metrorrhagia, menorrhagia, vaginal bleeding during pregnancy hematochezia, abdominal pain due to blood stasis, Puerperal placenta retention, dysentery stranguria with blood, hemorrhoid proctoptosis, skin eczema." classifying herbal " carries: " sterilization, removes wind, control back flower.”
Radix Polygoni Ciliinerve: sour in the mouth, hardship, puckery, cool in nature；Return lung, large intestine, Liver Channel.Anti-inflammation, pleasant invigorates blood circulation, cooling blood for hemostasis, calm Spasmolytic, pain-alleviating diarrhea-relieving.For tonsillitis, enteritis gastritis, Peptic Ulcers, bacillary dysentery, ascariasis of biliary tract, trauma infection contamination, cellulitis, Carbuncle furuncle, purulent, urinary system infection, menoxenia, metrorrhagia, hemorrhage haematemesis, epistaxis has blood in stool, traumatic injury, lumbago, skelalgia of rheumatism.Existing Confirming for medical research, staphylococcus aureus, escherichia coli, bacillus pyocyaneus, bacterium flexneri are had suppression to make by Radix Polygoni Ciliinerve With.
Herba Portulacae: sour in the mouth, cold in nature.Clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.For bacillary dysentery, acute gastroenteritis, acute vermiform appendix Inflammation, mastitis, bleeding hemorrhoids, leucorrhea, furuncle swelling toxin, eczema, herpes zoster." the SHENGCAO property of medicine standby will " carries: " control red diarrhea disease, clearly Pyretic toxicity, washes hemorrhoid infantile malnutrition furuncle." modern medicine study confirmation, Herba Portulacae is to escherichia coli, Salmonella, Bacillus proteus, will Hayes The bacteriostasis such as bacterium, staphylococcus aureus, bacillus subtilis, bacillus cereus are stronger.
Herba Pteridis Semipinnatae: bitter in the mouth, pungent, cool in nature.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For bacillary dysentery, acute enteritis, icteric Hepatitis, conjunctivitis, traumatic injury, traumatic hemorrhage, skin infection furuncle and phyma, eczema, venom.Modern medicine study confirms, Herba Pteridis Semipinnatae Staphylococcus aureus there is inhibitory action.
Cacumen Platycladi: bitter in the mouth, puckery, cold in nature；Return lung, liver, spleen channel.Cooling blood for hemostasis, wind-damp dispelling, dissipate toxic swelling.For hematemesis and epistaxis, Hematuria dysentery, hemorrhoidal hamorrhage metrorrhagia, rheumatic arthralgia, bacillary dysentery, hypertension, erysipelas of coughing, mumps is scalded.Modern medicine study is demonstrate,proved Real, Cacumen Platycladi is to tubercule bacillus, streptococcus pneumoniae, micrococcus catarrhalis, the joyous coccus of pneumonia, hemophilus influenza, staphylococcus aureus, pneumonia Bacillus and alpha streptococcus all have inhibitory action.
Radix Ardisiae Crenatae: bitter in the mouth, pungent, property is put down.Promoting the circulation of blood is dispeled the wind, removing toxic substances and promoting subsidence of swelling.For upper respiratory tract infection, laryngopharynx swelling and pain, almond Body is scorching, diphtheria, bronchitis, rheumatic arthritis, lumbago and skelalgia, traumatic injury, erysipelas, lymphadenitis, and wound swells and ache, fracture, Venom.Modern medicine study confirms, Radix Ardisiae Crenatae decoct has suppression to staphylococcus aureus, escherichia coli, bacillus pyocyaneus Effect.
Pseudobulbus Bletillae (Rhizoma Bletillae): sweet in the mouth, hardship, puckery, cold nature；Return lung, kidney channel.Astringing to arrest bleeding, detumescence and promoting granulation.Spit blood for hemoptysis, wound Hemorrhage, sore swollen toxin, chapped skin, pulmonary tuberculosis hemoptysis, ulcer haemorrhage.Modern medicine study confirms, Pseudobulbus Bletillae (Rhizoma Bletillae) is to golden yellow Portugal Grape coccus, bacillus subtilis and Bacillus tuberculosis have inhibitory action.
Herba Taraxaci: bitter in the mouth, sweet, cold in nature；Return liver, stomach warp.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.Swell for furuncle Poison, acute mastitis scrofula, conjunctival congestion pharyngalgia, lung abscess acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Modern medicine study confirms, Herba Taraxaci is to golden yellow Color staphylococcus Resistant strain, Hemolytic streptococcus have stronger bactericidal action, to Diplococcus pneumoniae, meningococcus, diphtheria Bacillus, bacillus pyocyaneus, Bacillus proteus, dysentery bacterium, Bacillus typhi and micrococcus catarrhalis also have certain bactericidal action.
The present invention compared with prior art, has the advantages that
Selected by cleaning solution of the present invention, medical material compatibility is suitable, meets Chinese medicine and modern medicine theoretical, have sterilizing ability strong, The advantages such as reagentia is fast, stability is strong, and non-stimulated to human body skin, with rear noresidue, soluble in water, the secondary work of safety non-toxic With, can be widely applied to the cleaning of clinical laboratory's operation equipment, improve the work efficiency of clinical laboratory personnel, it is ensured that assay Accuracy rate.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of cleaning solution effective ingredient of the present invention forms and weight is:
The preparation method of cleaning solution of the present invention, comprises the following steps that:
(1) Herba Erigerontis Annui, Radix et Caulis Opuntiae Dillenii and Herba Alternantherae sessilis are gone the removal of impurity, clean, be placed in strand juice in container, filter, obtain filtrate, standby With；
(2) Cortex Fraxini, Herba potentillae fulgentis, Herba Schizonepetae, emblic leafflower fruit, Receptaculum Nelumbinis and Radix Ardisiae Crenatae are gone the removal of impurity, clean, put in container, add 6 Times amount distilled water, soaks 4 hours, decocts 3 hours, extracts decoction liquor；Add 4 times amount distilled water, decoct 2 hours, extract and decoct Boil liquid, finally merge the decoction liquor extracted 2 times, filter, obtain filtrate, standby；
(3) Fructus Forsythiae, Herba Portulacae, Herba Pteridis Semipinnatae, Cacumen Platycladi and Herba Taraxaci are gone the removal of impurity, clean, fry with high heat in being placed in pot To burnt brown, spraying clear water, taking-up is dried, and grinds into powder in being placed in mortar, obtains the fine powder of 120 mesh, standby；
(4) Radix Polygoni Ciliinerve and Pseudobulbus Bletillae (Rhizoma Bletillae) are gone the removal of impurity, clean, section, it is placed in pot, sprays yellow wine and mix thoroughly, slow fire is fried extremely Yellow wine is sucked, and taking-up is dried, and grinds into powder in being placed in mortar, obtains the fine powder of 140 mesh, standby；
(5) 12 are added after step (1), the filtrate of step (2) gained being mixed with the fine powder of step (3), step (4) gained ～15 distilled water of times amount, stirring and dissolving uniformly after, heated and boiled 1 hour, to less than 60 DEG C, stands 1 hour, filtration, obtain filter Liquid, seals up for safekeeping filtrate fill, 121 DEG C of pressure sterilizings 30 minutes, and packaging is described checked operation equipment cleaning liquid.
Embodiment 2
The raw material of cleaning solution effective ingredient of the present invention forms and weight is:
The cleaning solution preparation method processing step of the present embodiment is same as in Example 1.
Embodiment 3
The raw material of cleaning solution effective ingredient of the present invention forms and weight is:
The cleaning solution preparation method processing step of the present embodiment is same as in Example 1.
Embodiment 4
The raw material of cleaning solution effective ingredient of the present invention forms and weight is:
The cleaning solution preparation method processing step of the present embodiment is same as in Example 1.
Experimental section
Below the selection present invention is tested accordingly, prove effect of the present invention further.
One, soluble test
1, take cleaning solution 10ml of the present invention and put in container, be subsequently adding distilled water, after stirring, filter.
2, after having filtered, filter paper is observed, without obvious residue on filter paper.
3, conclusion: cleaning solution of the present invention is highly soluble in water, uses rear noresidue impurity to occur.
Two, toxicity test
1, acute oral test: choose the healthy Kunming kind one-level mice 30 that body weight is 25～27g, male and female half and half, By cleaning solution per os gastric infusion of the present invention, it is administered and observes 15 days, record the various performance of mice and death condition every day, calculate LD. it is worth.
2, cumulative toxicity test: choose the healthy Kunming kind one-level rat 30 that body weight is 200～220g, male and female half and half, By cleaning solution per os gastric infusion of the present invention, dosage tests the DL. value drawn according to acute oral, the 1st～6 day, every time It is administered 0.1LD., within later every four hours, is incremented by 1.5 multiple doses, is administered 30 days, and every four hours weigh once, calculate accumulation system Number.
3, there is not death, solves it accordingly in result: no abnormality seen reaction after acute oral test mice perfusion After cuing open, tissue or internal organs have no obvious abnormal change.
After cumulative toxicity test is administered 30 days, male and female mice all occurs without death condition, mice cumulative coefficient 5, the weak storage in position Long-pending toxicity.
Three, Ocular irritation test
1, selecting healthy white rabbit 8, body weight is 4～5kg, cleaning solution stock solution 0.1ml of the present invention is instilled rabbit left In eye conjunctival sac, after passive Guan Bi 4s, instill normal saline with normal saline flushing, right eye as comparison.
2, rabbit 12 hours, 24 hours, 36 hours and 48 hours interior eyes localized variation are observed.
3, result: the cornea and the iris that contaminate the rabbit of cleaning solution of the present invention are normal, and conjunctiva has no edema, has slight hyperemia, Conjunctiva stimulation index is 1, by acute ocular stimulus intensity analytic intensity grade scale, belongs to nonirritant.
Four, irritation test
1, selecting healthy white rabbit 8, body weight is 3.6～4.0kg, the depilation of family's rabbit back spinal column both sides is respectively 5.0cm × 5.0cm, does not damage epidermis, after 24 hours, by cleaning solution uniform application of the present invention for 0.3ml in the left side of baring skin, Right side is not smeared as comparison, after 10 hours, skin wiping is clean, observes dermoreaction, carries out stimulating scoring.
2, result: rabbit baring skin there are no erythema and edema reaction, and skin wound repair integrated value is 0, control sides Skin no abnormality seen, by skin wound repair standards of grading, reaction integral mean value is 0, and cleaning solution of the present invention is non-stimulated to skin Property.
Five, stability test
Take cleaning solution 50ml of the present invention, after placing 90 days under the conditions of 37 DEG C, for staphylococcus aureus is killed No significant difference is compared before bacterium, its bactericidal effect and storage.
Six, bacteriostatic test
Below cleaning solution of the present invention is carried out bacteriostatic experiment:
1, experimental strain:
Select the strain that laboratory is representative, staphylococcus aureus and escherichia coli.
2, bacterium culture medium:
Nutrient agar and nutrient broth medium.
3, experiment classification:
Bacteriostatic experiment divides experimental group and matched group, and experimental group selects cleaning solution of the present invention, and matched group selects hypochlorous acid sterilization Liquid.
4, specific experiment step:
(1) preparation of bacterium solution: be inoculated in respectively by above two strain on two agar culture mediums, cultivates 24 at 37 DEG C Hour, during from above-mentioned agar culture medium, picking colonies typical is inoculated in two fresh nutrient broth mediums respectively respectively, Under synthermal, cultivate 24 hours, standby；
(2) take cleaning solution of the present invention and each 30ml of hypochlorous acid disinfectant solution, be respectively placed in cut-back tank, it is diluted respectively 25 times, above two diluent solution is split in two containers respectively, is placed under aseptic condition, standby；
(3) above-mentioned steps (1) is supported the experimental strain of 24 hours through nutrition broth cultivation the dilutest with aseptic nutrient broth Releasing 50 times, every kind of strain is sub-packed in two culture dishs, respectively labelling matched group and experimental group；
(4) dilute solution of two portions of cleaning solutions of the present invention of above-mentioned steps (2) gained is respectively dropped into experimental group culture dish, Two parts of hypochlorous acid disinfectant solution dilute solutions are respectively dropped into matched group culture dish.
5, experimental observation is measured:
Above-mentioned experiment is observed, observes two groups of strains and measure strain revolution mark concrete outcome.
6, after observation is measured, it is placed in above-mentioned culture dish under aseptic condition standing two days, treats that liquid volatilizees completely After, follow the tracks of it has been observed that matched group bacterium colony continues breeding, and experimental group bacterium colony is unchanged.
7, experimental result:
The sterilizing ability of experimental group cleaning solution of the present invention is much larger than the sterilizing ability of matched group chloric acid disinfectant solution, and can All kinds of strain is suppressed to continue breeding.

Claims (5)

1. a checked operation equipment cleaning liquid, it is characterised in that: make raw material composition and the weight of described cleaning solution effective ingredient Amount number is:
Herba Erigerontis Annui 48～78 parts of Cortex Fraxinis 45～75 parts of Herba potentillae fulgentis 43～73 portions of Herba Schizonepetae 41～71 parts
Fructus Forsythiae 38～68 parts of emblic leafflower fruits 33～63 parts of Radix et Caulis Opuntiae Dilleniis 30～60 parts of Herba Alternantherae sessiliss 28～58 parts
Receptaculum Nelumbinis 26～56 parts of Radix Polygoni Ciliinerves 23～21～51 parts of Herba Pteridis Semipinnataes of 53 portions of Herba Portulacaes 19～49 parts
Cacumen Platycladi 18～48 parts of Radix Ardisiae Crenataes 14～44 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) 13～43 parts of Herba Taraxacis 8～38 parts.
A kind of checked operation equipment cleaning liquid the most according to claim 1, it is characterised in that: make described cleaning solution effective The raw material of composition forms and parts by weight are:
71 parts of Cortex Fraxinis of Herba Erigerontis Annui, 66 portions of Herba Schizonepetae of 68 parts of Herba potentillae fulgentis 64 parts
61 parts of emblic leafflower fruits of Fructus Forsythiae, 54 parts of Herba Alternantherae sessiliss of 56 parts of Radix et Caulis Opuntiae Dilleniis 52 parts
50 parts of Radix Polygoni Ciliinerves of Receptaculum Nelumbinis, 44 parts of Herba Pteridis Semipinnataes of 46 portions of Herba Portulacaes 42 parts
41 parts of Radix Ardisiae Crenataes of Cacumen Platycladi, 36 parts of Herba Taraxacis of 37 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) 31 parts.
A kind of checked operation equipment cleaning liquid the most according to claim 1, it is characterised in that: make described cleaning solution effective The raw material of composition forms and parts by weight are:
64 parts of Cortex Fraxinis of Herba Erigerontis Annui, 59 portions of Herba Schizonepetae of 61 parts of Herba potentillae fulgentis 57 parts
54 parts of emblic leafflower fruits of Fructus Forsythiae, 47 parts of Herba Alternantherae sessiliss of 49 parts of Radix et Caulis Opuntiae Dilleniis 44 parts
43 parts of Radix Polygoni Ciliinerves of Receptaculum Nelumbinis, 37 parts of Herba Pteridis Semipinnataes of 39 portions of Herba Portulacaes 35 parts
34 parts of Radix Ardisiae Crenataes of Cacumen Platycladi, 29 parts of Herba Taraxacis of 30 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) 24 parts.
A kind of checked operation equipment cleaning liquid the most according to claim 1, it is characterised in that: make described cleaning solution effective The raw material of composition forms and parts by weight are:
56 parts of Cortex Fraxinis of Herba Erigerontis Annui, 51 portions of Herba Schizonepetae of 52 parts of Herba potentillae fulgentis 50 parts
46 parts of emblic leafflower fruits of Fructus Forsythiae, 38 parts of Herba Alternantherae sessiliss of 41 parts of Radix et Caulis Opuntiae Dilleniis 37 parts
32 parts of Radix Polygoni Ciliinerves of Receptaculum Nelumbinis, 30 parts of Herba Pteridis Semipinnataes of 31 portions of Herba Portulacaes 27 parts
26 parts of Radix Ardisiae Crenataes of Cacumen Platycladi, 21 parts of Herba Taraxacis of 22 parts of Pseudobulbus Bletillae (Rhizoma Bletillae) 16 parts.
5. the preparation method of checked operation equipment cleaning liquid as described in any one of Claims 1 to 4, it is characterised in that: bag Include following processing step:
(1) Herba Erigerontis Annui, Radix et Caulis Opuntiae Dillenii and Herba Alternantherae sessilis are gone the removal of impurity, clean, be placed in strand juice in container, filter, obtain filtrate, standby；
(2) Cortex Fraxini, Herba potentillae fulgentis, Herba Schizonepetae, emblic leafflower fruit, Receptaculum Nelumbinis and Radix Ardisiae Crenatae are gone the removal of impurity, clean, put in container, add 6 times amount Distilled water, soaks 4 hours, decocts 3 hours, extracts decoction liquor；Add 4 times amount distilled water, decoct 2 hours, extract decoction liquor, Finally merge the decoction liquor extracted 2 times, filter, obtain filtrate, standby；
(3) Fructus Forsythiae, Herba Portulacae, Herba Pteridis Semipinnatae, Cacumen Platycladi and Herba Taraxaci are gone the removal of impurity, clean, fry with high heat to burnt in being placed in pot Brown, sprays clear water, and taking-up is dried, and grinds into powder in being placed in mortar, obtains the fine powder of 120 mesh, standby；
(4) Radix Polygoni Ciliinerve and Pseudobulbus Bletillae (Rhizoma Bletillae) are gone the removal of impurity, clean, section, it is placed in pot, sprays yellow wine and mix thoroughly, slow fire is fried to yellow wine Being sucked, taking-up is dried, and grinds into powder in being placed in mortar, obtains the fine powder of 140 mesh, standby；
(5) 12～15 are added after step (1), the filtrate of step (2) gained being mixed with the fine powder of step (3), step (4) gained The distilled water of times amount, after stirring and dissolving is uniform, heated and boiled 1 hour, to less than 60 DEG C, stand 1 hour, filter, obtain filtrate, will Filtrate fill is sealed up for safekeeping, 121 DEG C of pressure sterilizings 30 minutes, and packaging is described checked operation equipment cleaning liquid.
CN201610562681.XA 2016-07-15 2016-07-15 A kind of checked operation equipment cleaning liquid and preparation method Pending CN106259526A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108041088A (en) * 2018-01-12 2018-05-18 宋瑞红 A kind of clinical laboratory's Traditional Chinese medicine air disinfectant and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104542740A (en) * 2015-01-27 2015-04-29 王淑芹 Traditional Chinese medicine disinfectant for sterilization and disinfection of clinical laboratory instruments and preparation method of traditional Chinese medicine disinfectant
CN105343652A (en) * 2015-12-21 2016-02-24 张学军 Hand sanitizer for clinical laboratory and preparation method
CN105535297A (en) * 2016-02-24 2016-05-04 韩邦森 Disinfecting traditional Chinese herb preparation for clinical laboratory and preparing method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104542740A (en) * 2015-01-27 2015-04-29 王淑芹 Traditional Chinese medicine disinfectant for sterilization and disinfection of clinical laboratory instruments and preparation method of traditional Chinese medicine disinfectant
CN105343652A (en) * 2015-12-21 2016-02-24 张学军 Hand sanitizer for clinical laboratory and preparation method
CN105535297A (en) * 2016-02-24 2016-05-04 韩邦森 Disinfecting traditional Chinese herb preparation for clinical laboratory and preparing method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108041088A (en) * 2018-01-12 2018-05-18 宋瑞红 A kind of clinical laboratory's Traditional Chinese medicine air disinfectant and preparation method thereof

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Application publication date: 20170104