CN105663725A - Disinfection traditional Chinese medicine preparation for clinical laboratory, and preparation method of disinfection traditional Chinese medicine preparation - Google Patents

Disinfection traditional Chinese medicine preparation for clinical laboratory, and preparation method of disinfection traditional Chinese medicine preparation Download PDF

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Publication number
CN105663725A
CN105663725A CN201610107914.7A CN201610107914A CN105663725A CN 105663725 A CN105663725 A CN 105663725A CN 201610107914 A CN201610107914 A CN 201610107914A CN 105663725 A CN105663725 A CN 105663725A
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parts
herba
radix
fructus
chinese medicine
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王英英
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/40Liliopsida [monocotyledons]
    • A01N65/42Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives
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    • A61K36/11Pteridophyta or Filicophyta (ferns)
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Abstract

The invention relates to a disinfection traditional Chinese medicine preparation for a clinical laboratory. The disinfection traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 4-6 parts of tender catchweed bedstraw herb, 8-12 parts of herba goodyera repens, 3-4 parts of feather cockscomb, 12-15 parts of small purslane herb, 5-9 parts of spina gleditsiae, 3-4 parts of philippine violet herb, 5-8 parts of herba pteris vittata, 12-16 parts of spica prunellae, 10-16 parts of shinyleaf pricklyash root, 3-8 parts of cyrtomium rhizome, 5-12 parts of sweet wormwood herb, 5-10 parts of cannalike dona rhizome, 5-10 parts of dandelion, 13-16 parts of Chinese sumac fruit, 5-10 parts of herba polycarpaea corymbosa, 8-13 parts of folium artemisiae argyi, 5-10 parts of glyptostrobus pensilis, 9-15 parts of sowthistle tasselflower herb, 3-7 parts of garlic, 8-13 parts of cactus, 3-5 parts of ligustrum sinense, 1-3 parts of winged laggera herb, 12-17 parts of folium isatidis, 7-12 parts of folium eucalypti, 4-9 parts of radix angelicae, 15-20 parts of cortex magnoliae officinalis, 10-15 parts of radix tripterygii wilfordii, 8-12 parts of puberulous glochidion herb, 2-5 parts of radix sophorae flavescentis, 3-7 parts of honeysuckle flower, 11-14 parts of Chinese honeylocust fruit, 9-15 parts of wild chrysanthemum flower and 3-6 parts of burdock fruit.

Description

A kind of clinical laboratory sterilizing Chinese medicine preparation and preparation method thereof
Technical field
The invention belongs to pharmaceutical technology field, relate to a kind of Chinese medicine composition, be specifically related to a kind of clinical laboratory sterilizing Chinese medicine preparation and preparation method thereof.
Background technology
Clinical laboratory is the bridge between clinical medicine and preclinical medicine, undertakes the detection work of various human bodies and the zoological specimens including ward, Emergency call patient, all kinds of health check-up and scientific research every day, including blood, urine sample, excrement sample etc.
In the course of the work, owing to medical personnel are often in contact with these samples, therefore, it is very easy to the upper antibacterials of contamination. When clinical laboratory personnel test, the both hands of oneself must be carried out disinfection, at present frequently with method be immersed in disinfectant solution, existing disinfectant solution is mainly ethanol, hydrogen peroxide, iodine tincture, potassium permanganate, also has glutaraldehyde, povidone iodine etc. These disinfectant solution are mostly chemicals, have strong impulse, and commonly used meeting makes medical personnel's skin be subject to serious stimulation, and the watch face of the people of some allergy can become dry and crowfoot cracks, and dermatitis and eczema even can occur. And reusing of disinfectant solution is developed immunity to drugs so that antibacterial etc., have a strong impact on Disinfection Effect, not only increase the work difficulty of reviewer, also have impact on the result of inspection. Medical worker is after analyzing and processing of testing, need that inspection apparatus carries out unify sterilization to clean, conventional cleaning method is to adopt manually to be carried out, occurred in that new sterilization method later, such as disinfection by ultraviolet light, microwave radiation is sterilized, and tentatively cleaned inspection apparatus is placed in special device and carries out disinfection and store, but such sterilization method exists certain defect. Although adopting the method that special device carries out unifying sterilization can kill Most bacterial and virus; but the bloodstain pus mark remained on inspection apparatus and secretions etc. cannot be purged; the Proteinaceous Organic substance polluted on inspection apparatus cleans not thorough; microorganism had protective effect; easily cause sterilizing failure; take out after sterilization and can breed bacteria again, it is impossible to ensure absolute sanitation and hygiene.
Simultaneously, it is known that, when medical institutions carry out medical test, the bacterial flora system of checking system should minimize, this just needs the trier that medical personnel itself and inspection are required is carried out omnibearing to sterilize thoroughly, eliminate a series of antibacterial and pathogen such as staphylococcus aureus, escherichia coli, Salmonella typhi, Pseudomonas aeruginosa, proteus vulgaris etc., provide good environment for checking system.
The disinfectant being currently used for processing inspection section office has a lot, but has certain side effect, and reviewer is not easily chronically at section indoor, affects the healthy of reviewer time serious. Thus for check medicine that section office sterilize must safely, effectively, have no side effect, and Chinese materia medica is as the traditional medicine of China, there is the advantages such as effect strong, instant effect, lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore select a kind of sterilizing Chinese medicine composition for clinical laboratory's sterilization Chinese medicine preparation, for checking the environment tool of section office to be of great significance.
Summary of the invention
The invention provides a kind of clinical laboratory sterilizing Chinese medicine preparation and preparation method thereof, selected by this Chinese medicine preparation, medical material compatibility is suitable, meets Chinese medicine and modern medicine is theoretical, there is the effects such as heat-clearing and toxic substances removing, bacteriostasis and sterilization, parasite killing antiinflammatory, and human body skin is non-stimulated, safe without toxic side effect.
The above-mentioned purpose of the present invention is realized by following technical proposals:
A kind of clinical laboratory sterilizing Chinese medicine preparation, make described Chinese medicine preparation raw material composition and parts by weight be: Herba Galii Teneri 4-6 part, Herba goodyearae repentis 8-12 part, Herba Celosiae argenteae 3-4 part, little Herba Portulacae 12-15 part, Spina Gleditsiae 5-9 part, Herba Violae 3-4 part, Herba pteridis vittatae 5-8 part, Spica Prunellae 12-16 part, Radix Zanthoxyli 10-16 part, Rhizoma Osmundae 3-8 part, Herba Artemisiae Annuae 5-12 part, Rhizoma Donacis canniformis 5-10 part, Herba Taraxaci 5-10 part, Fructus rhois chinensis 13-16 part, Herba Polycarpaeae Corymbosae 5-10 part, Folium Artemisiae Argyi 8-13 part, Codium fragile (Sur.) Har. 5-10 part, Herba Emiliae 9-15 part, Bulbus Allii 3-7 part, Radix et Caulis Opuntiae Dillenii 8-13 part, ligustrum sinense 3-5 part, Herba Laggerae Alatae 1-3 part, Folium Isatidis 12-17 part, Folium eucalypti globueli (Eucalyptus globulus Labill.) 7-12 part, Radix Angelicae Dahuricae 4-9 part, Cortex Magnoliae Officinalis 15-20 part, Radix Tripterygii Wilfordii 10-15 part, Fructus glochidionis puberi(Herba Glochidii Puberi) 8-12 part, Radix Sophorae Flavescentis 2-5 part, Flos Lonicerae 3-7 part, Fructus Gleditsia 11-14 part, Flos Chrysanthemi Indici 9-15 part, Fructus Arctii 3-6 part.
Further, make described Chinese medicine composition raw material composition and parts by weight be: Herba Galii Teneri 6 parts, Herba goodyearae repentis 8 parts, Herba Celosiae argenteae 3 parts, little Herba Portulacae 15 parts, Spina Gleditsiae 5 parts, Herba Violae 3 parts, Herba pteridis vittatae 5 parts, Spica Prunellae 12 parts, Radix Zanthoxyli 16 parts, Rhizoma Osmundae 3 parts, Herba Artemisiae Annuae 12 parts, Rhizoma Donacis canniformis 10 parts, Herba Taraxaci 5 parts, Fructus rhois chinensis 16 parts, Herba Polycarpaeae Corymbosae 10 parts, Folium Artemisiae Argyi 8 parts, Codium fragile (Sur.) Har. 10 parts, Herba Emiliae 15 parts, 3 parts of Bulbus Allii, Radix et Caulis Opuntiae Dillenii 8 parts, ligustrum sinense 5 parts, Herba Laggerae Alatae 1 part, Folium Isatidis 12 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 parts, the Radix Angelicae Dahuricae 9 parts, Cortex Magnoliae Officinalis 15 parts, Radix Tripterygii Wilfordii 15 parts, Fructus glochidionis puberi(Herba Glochidii Puberi) 8 parts, Radix Sophorae Flavescentis 5 parts, Flos Lonicerae 3 parts, 14 parts of Fructus Gleditsia, Flos Chrysanthemi Indici 9 parts, Fructus Arctii 6 parts.
Further, make described Chinese medicine composition raw material composition and parts by weight be: Herba Galii Teneri 4 parts, Herba goodyearae repentis 10 parts, Herba Celosiae argenteae 4 parts, little Herba Portulacae 13 parts, Spina Gleditsiae 6 parts, Herba Violae 4 parts, Herba pteridis vittatae 8 parts, Spica Prunellae 16 parts, Radix Zanthoxyli 10 parts, Rhizoma Osmundae 8 parts, Herba Artemisiae Annuae 5 parts, Rhizoma Donacis canniformis 5 parts, Herba Taraxaci 10 parts, Fructus rhois chinensis 13 parts, Herba Polycarpaeae Corymbosae 7 parts, Folium Artemisiae Argyi 13 parts, Codium fragile (Sur.) Har. 5 parts, Herba Emiliae 9 parts, 7 parts of Bulbus Allii, Radix et Caulis Opuntiae Dillenii 10 parts, ligustrum sinense 3 parts, Herba Laggerae Alatae 3 parts, Folium Isatidis 17 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 12 parts, the Radix Angelicae Dahuricae 4 parts, Cortex Magnoliae Officinalis 20 parts, Radix Tripterygii Wilfordii 10 parts, Fructus glochidionis puberi(Herba Glochidii Puberi) 12 parts, Radix Sophorae Flavescentis 2 parts, Flos Lonicerae 7 parts, 11 parts of Fructus Gleditsia, Flos Chrysanthemi Indici 15 parts, Fructus Arctii 3 parts.
Further, make described Chinese medicine composition raw material composition and parts by weight be: Herba Galii Teneri 5 parts, Herba goodyearae repentis 12 parts, Herba Celosiae argenteae 3 parts, little Herba Portulacae 12 parts, Spina Gleditsiae 9 parts, Herba Violae 4 parts, Herba pteridis vittatae 7 parts, Spica Prunellae 13 parts, Radix Zanthoxyli 13 parts, Rhizoma Osmundae 6 parts, Herba Artemisiae Annuae 9 parts, Rhizoma Donacis canniformis 6 parts, Herba Taraxaci 6 parts, Fructus rhois chinensis 14 parts, Herba Polycarpaeae Corymbosae 5 parts, Folium Artemisiae Argyi 10 parts, Codium fragile (Sur.) Har. 6 parts, Herba Emiliae 10 parts, 5 parts of Bulbus Allii, Radix et Caulis Opuntiae Dillenii 13 parts, ligustrum sinense 4 parts, Herba Laggerae Alatae 2 parts, Folium Isatidis 13 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 7 parts, the Radix Angelicae Dahuricae 5 parts, Cortex Magnoliae Officinalis 18 parts, Radix Tripterygii Wilfordii 11 parts, Fructus glochidionis puberi(Herba Glochidii Puberi) 9 parts, Radix Sophorae Flavescentis 4 parts, Flos Lonicerae 6 parts, 12 parts of Fructus Gleditsia, Flos Chrysanthemi Indici 13 parts, Fructus Arctii 4 parts.
The preparation method that the invention still further relates to a kind of clinical laboratory sterilizing Chinese medicine preparation, comprises the steps:
(1) take Folium Isatidis, Bulbus Allii, Herba Galii Teneri, Radix et Caulis Opuntiae Dillenii and little Herba Portulacae strand juice, filter impurity, stay juice, standby;
(2) Flos Chrysanthemi Indici, Flos Lonicerae, Herba Emiliae, Herba Laggerae Alatae, Cortex Magnoliae Officinalis, Spina Gleditsiae, Herba pteridis vittatae, Spica Prunellae, Radix Zanthoxyli, the Radix Angelicae Dahuricae, Radix Tripterygii Wilfordii and Rhizoma Donacis canniformis decontamination are cleaned, it is placed in container, add the distilled water immersion of 8-10 times amount after 5-6 hour, boil 3-4 hour, extract; Again add 5-7 times amount distilled water, boil 2-3 hour, extract; Finally, add 2-4 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, obtain filtrate, standby;
(3) Folium Artemisiae Argyi, Fructus Arctii, Codium fragile (Sur.) Har., Herba Celosiae argenteae, Herba Violae, Rhizoma Osmundae, Fructus glochidionis puberi(Herba Glochidii Puberi) and Herba Artemisiae Annuae are smashed it is subsequently adding ethanol, sealing is placed in shady and cool ventilation place and stands 5-7 days, filtering, filtering residue adds water boiled with high heat, changes slow fire and adds thermal distillation 1-2 hour, volatile oil and water is made together to distill, collect distillate, stand 50-70 minute, distillate is cooled to room temperature, take upper strata fluid, obtain volatile oil stand-by;
(4) Radix Sophorae Flavescentis, Fructus Gleditsia, Herba Taraxaci, ligustrum sinense, Fructus rhois chinensis, Herba goodyearae repentis being cleaned chopping, with 3-8 times amount 80% ethanol, with the speed diafiltration of 3ml/min, filtered by percolate, filtrate is stand-by;
(5) by Folium eucalypti globueli (Eucalyptus globulus Labill.) and Herba Polycarpaeae Corymbosae decontamination, clean, be placed in frying pan, heat with slow fire, fry and be advisable to micro-the changing of coat tablets, take out airing, be placed in mortar, grind into powder, obtained the fine powder of 120 orders, standby;
(6) juice that step (1) is prepared, the filtrate that step (2), (4) prepare, the volatile oil of step (3) gained, after the fine powder mixing that step (5) prepares, the distilled water adding 10-12 times amount stirs, heated and boiled 0.5 hour, standing 1 hour, extraction filters to get filtrate, and filtrate fill is sealed up for safekeeping, 122 DEG C of-125 DEG C of pressure sterilizings 20-30 minute, Ji get clinical laboratory sterilizing Chinese medicine preparation.
Clinical laboratory provided by the present invention sterilizing Chinese medicine preparation, raw material includes:
Herba Galii Teneri: acrid in the mouth, hardship, cool in nature; Return lung, stomach, spleen, Liver Channel. Clearing away damp-heat, dissipating blood stasis, detumescence, removing toxic substances. Control stranguria with turbid discharge, hematuria, traumatic injury, acute appendicitis, furuncle and phyma, otitis media. " Kunming conventional medical herbs among the people " carries: " heat clearing and inflammation relieving, wind-damp dispelling, dissipating blood stasis blood, control phlegm-fire heat symptom-complex, and acute conjunctivitis mist gum is many, rheumatic bone-setting pain, the subcutaneous congestive edema of wound. " modern medicine study confirmation, staphylococcus aureus, escherichia coli, shigella etc. are had inhibitory action by Herba Galii Teneri.
Herba goodyearae repentis: lightly seasoned, cold in nature. Clearing away lung-heat to relieve cough, removing toxic substances and promoting subsidence of swelling, pain relieving. Cough for pulmonary tuberculosis, bronchitis, venom, carbuncle furuncle infections. " Zhejiang conventional medical herbs among the people " carries: " heat-clearing and toxic substances removing, antiinflammatory detumescent. Controlling venom, carbuncle furuncle, pneumonopathy is coughed, tracheitis. "
Herba Celosiae argenteae: bitter in the mouth, cold in nature; Return liver, bladder warp. Dampness heat clearing away, killing parasites for relieving itching, cooling blood for hemostasis. Main damp-heat vaginal discharge, dysuria, turbid urine, have loose bowels, pudendal pruritus, skin ulcer scabies, wind scabies itching over the body, hemorrhoid, epistaxis, wound hemorrhage. Shennong's Herbal carries: " main pathogen, in skin, heat, wind scabies itching over the body, kill three worms. "
Little Herba Portulacae: the micro-acid of taste, micro-hardship, property is put down. Dysentery relieving sterilizes. Cure mainly dysentery, enteritis, diarrhoea, humid jaundice, Internal hemorrhoid hemorrhage, hypogalactia, infantile malnutrition, impetigo, chronic ulcer of lower extremity.
Spina Gleditsiae: acrid in the mouth, warm in nature; Return liver, lung meridian. For controlling swollen ulcer drug, scrofula, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention, leprosy. Modern medicine study confirms, staphylococcus aureus and other coccuses are had inhibitory action by Spina Gleditsiae decoct.
Herba Violae meridian distribution of property and flavor: bitter, acrid, cold is nontoxic; GUIXIN, Liver Channel. Function with cure mainly: heat-clearing and toxic substances removing, removing heat from blood subside a swelling. Cure mainly jaundice, dysentery.
Herba pteridis vittatae: lightly seasoned is bitter; Cool in nature. Return liver; Large intestine; Bladder warp. Expelling wind and removing dampness; Relaxing muscles and tendons and activating QI and blood in the collateral; Removing toxic substances parasite killing. Main air wets bones and muscles pain; Lumbago; Limb fiber crops joint stuffiness; Hemiplegia; Traumatic injury; Flu; Dysentery; Acute mastitis; Sore; Scabies; Ascariasis; Serpentis is early bitten.
Spica Prunellae: nature and flavor: pungent, bitter, cold. Gui Jing: return liver, gallbladder meridian. Cure mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence. For conjunctival congestion and swelling pain, order pearl nyctalgia, dizziness of having a headache, scrofula, goiter, acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Radix Zanthoxyli: promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral. Belong to the blood-activating analgesic of classification under drug for invigorating blood circulation and eliminating stasis; The alkaloids compositions such as alkali, nitidine chloride, oxyterihanine are determined containing nitidine, chelerythrine, different precipice green pepper. Radix Zanthoxyli extract lumbar injection, to the reaction of mice acetic acid twisting, K+ penetrates and photo-thermal stimulus method all has analgesic activity. Also has antibacterial action. Additionally, tool maincenter calmness, spasmolytic, antitumaous effect. Injection and crystallization 1 tablet, can treat neuralgia, headache, lumbago and skelalgia, rheumatic arthritis and gastrointestinal, the outer pain of injury, headache due to common cold and minor operation local anesthesia, pain relieving etc.
Rhizoma Osmundae: bitter in the mouth, puckery, cold nature, slightly poisonous; Return liver, stomach warp. Parasite killing, heat clearing away, removing toxic substances, cooling blood for hemostasis. Main anemopyretic cold, warms skin eruption, spits blood, hemoptysis, and epistaxis is had blood in stool, metrorrhagia, dysentery, the intestinal parasitic disease such as leukorrhagia and hook, ascarid, cestode. " Chinese herbal medicine handbook is commonly used in northeast " carries: " anthelmintic, hemostasis, heat-clearing and toxic substances removing. Control ascarid, cestode, abdominal pain due to worm stagnation; Anovulatory dysfunctional uterine hemorrhage, leucorrhea. Rhizoma Osmundae is placed in water vat, drinks its water, prevents influenza, flu, epidemic cerebrospinal meningitis, measles. "
Herba Artemisiae Annuae: staphylococcus epidermidis, micrococcus catarrhalis, anthrax bacillus, diphtheria corynebacterium are had stronger bacteriostasis by Herba Artemisiae Annuae decocting liquid, also has certain inhibitory action to staphylococcus aureus, bacillus pyocyaneus, dysentery bacterium, tuberculosis stalk bacterium etc. All dermatophytosises, when 0.25% concentration, are had bacteriostasis by Herba Artemisiae Annuae volatile oil, when 1% concentration, all dermatophytosises are had bactericidal action. Herba Artemisiae Annuae have the effect of resisiting influenza virus. Sodium artesunate is to gold Fructus Vitis viniferae, shigella flexneri, anthrax bacillus, micrococcus catarrhalis, and A type and paratyphoid B stalk bacterium all have certain antibacterial action. Sitosterol and stigmasterol in Herba Artemisiae Annuae also have antivirus action.
Rhizoma Donacis canniformis: lightly seasoned, cool in nature; Return lung meridian. Heat-clearing and toxic substances removing, relieving cough and relieving asthma, anti-inflammation and sterilization. For pulmonary tuberculosis, tracheitis, bronchitis, asthma, high heat, infantile measles, merge pneumonia, flu, heating, various dermatosiss. Modern medicine study confirms, Rhizoma Donacis canniformis is inhibited to dysentery bacterium, Bacillus typhi, bacillus pyocyaneus, staphylococcus etc., and antimicrobial spectrum is also wider.
Herba Taraxaci: bitter in the mouth, sweet, cold in nature; Return liver, stomach warp. Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome. For furuncle swelling toxin, acute mastitis scrofula, conjunctival congestion pharyngalgia, lung abscess acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria. " Amplification on Materia Medica addendum " carries: " heat-transformation poison, the swollen tuberculosis of the evil that disappears, Detoxicating food-poisoning, dissipate stagnant gas. "
Fructus rhois chinensis: sour in the mouth, salty, cool in nature. Promoting the production of body fluid for nourishing the lung, lowering fire and resolving phlegm, arresting sweating dysentery relieving. Main phlegmatic cough, sore throat, jaundice, night sweat, dysentery, stubborn dermatitis, carbuncle poison, seborrheic dermatitis of the scalp. " detailed outline " carries: " body-fluid-generating heat-clearing, reduces phlegm, lung moistening nourishing kidney, sterilization, and dysentery relieving receives antiperspirant. Dispelling the wind and dampness pathogens, oculopathy. "
Herba Polycarpaeae Corymbosae: acrid in the mouth, hardship, warm in nature; GUIXIN, liver, lung, stomach warp. Heat-clearing and toxic substances removing, diuresis. For dysentery, enteritis, gonorrhea difficulty and pain in micturition, swollen ulcer drug.
Folium Artemisiae Argyi: warming the meridian for stopping bleeding, dispersing cold for relieving pain; External removing dampness to relieve itching. Cure mainly for spitting blood, epistaxis, metrorrhagia, menorrhagia, vaginal bleeding during pregnancy hematochezia, few abdomen cold type of pain, coldness and unbalance in meridians, cold womb is infertile; External treatment skin pruritus. Vinegar Chinese mugwort charcoal warming the meridian for stopping bleeding is hemorrhage for deficient cold type.
Codium fragile (Sur.) Har.: sweet in the mouth, salty, cold in nature; Return bladder, large intestine channel. Inducing diuresis to remove edema, parasite killing detoxifies. Main edema, ascariasis, heatstroke, dysuria. Collective Notes to the Canon of Materia medica carries: " treat small stream poison. " modern medicine study confirmation, Codium fragile (Sur.) Har. leachate anthelminthic effect relatively Digenea simplex (Wnlf.) C. Ag. is strong three times. Codium fragile (Sur.) Har. ingredient acrylic acid has powerful bacteriostasis. Linalool and geraniol have antibacterial, antifungic action.
Herba Emiliae: bitter in the mouth, cool in nature. Heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling. Your Majesty's respiratory tract infection, oral ulcer, pneumonia, mastitis, enteritis, bacillary dysentery, urinary tract infection, furuncle carbuncle, eczema, traumatic injury. " Guangxi practicality Chinese herbal medicine newly selects " carries: " anti-inflammation. Control acute upper respiratory tract inflammation, pneumonia, tonsillitis, oral ulcer, mastitis, chronic pelvic inflammatory disease, dysentery, diarrhoea, venom. "
Bulbus Allii: acrid in the mouth, warm in nature; Return spleen, stomach, lung, large intestine channel. Warming middle-JIAO row is stagnant, removing toxic substances, parasite killing. Main coldness and pain in the epigastrium, dysentery, have loose bowels, pulmonary tuberculosis, pertussis, flu, carbuncle furuncle and phyma poison, acute appendicitis, tinea skin ulcer, snake bite and insect sting, ancylostomiasis, enterobiasis, leukorrhagia pudendal pruritus, malaria, sore throat, edema. " not Lu " load: " dissipate carbuncle skin ulcer, exorcising, gas of killing virus. " modern medicine study confirmation, pyococcus, tubercule bacillus, dysentery bacterium, Bacillus typhi, Salmonella paratyphi, vibrio cholera etc. are in vitro all had inhibitory action by uncooked garlic; To green grass or young crops, chain, chlorine, chlortetracycline drug resistance antibacterial garlic preparation is still sensitive. Meningococcus is had stronger bacteriostasis by uncooked garlic infusion in vitro; Multiple pathogenic dermatophytes (including Candida albicans) all there are inhibitory action in various degree or killing action; Dermacetor orientalis is had and very strong presses down the power of killing.
Radix et Caulis Opuntiae Dillenii: bitter in the mouth, cold in nature; GUIXIN, lung, stomach warp. Promoting flow of QI and blood, heat-clearing and toxic substances removing, cooling blood for hemostasis, clearing away lung-heat to relieve cough. Main stomachache, mass in the abdomen, dysentery, laryngalgia, cough due to lung-heat, pulmonary tuberculosis is spat blood, and spits blood, hemorrhoidal bleeding, skin infection furuncle furuncle, acute mastitis, the cheek of itching, tinea, and snake bite and insect sting is scalded, cold injury. " Luchuan book on Chinese herbal medicine " load: " eliminating inflammation and expelling toxin, evacuation of pus granulation promoting. Cure mainly carbuncle sore furuncle and phyma, cough. " modern medicine study confirmation, Radix et Caulis Opuntiae Dillenii is the most significant to staphylococcus aureus inhibition, and 18 resistance to penicillin systems of this bacterium are also had inhibitory action highly. Additionally bacillus subtilis is also had height inhibitory action.
Ligustrum sinense: bitter in the mouth, cool in nature; Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling. Main cold, fever, cough due to lung-heat, laryngopharynx swelling and pain, aphtha of the mouth and tongue, jaundice due to damp-heat, dysentery, carbuncle sore tumefacting virus, eczema, dermatitis, traumatic injury, scald. Modern medicine study confirms, ligustrum sinense leaf is to staphylococcus aureus, Bacillus typhi. Paratyphoid bacillus A, bacillus pyocyaneus, escherichia coli, bacterium flexneri, pneumobacillus have extremely strong antibacterial action.
Herba Laggerae Alatae: acrid in the mouth, hardship, slightly warm in nature. Expelling wind and removing dampness, dissipating blood stasis, removing toxic substances. Main cold, fever, cough due to lung-heat, rheumatic arthritis, diarrhoea, oedema due to nephritis, amenorrhea, traumatic injury, furuncle carbuncle, scrofula, venom, eczema pruritus. " south of the Five Ridges gather medicinal herbs record " load: " dissipating blood stasis blood, detoxification. Treating snakebite, disappear malignant boil, controls traumatic injury wound. " modern medicine study confirmation, Herba Laggerae Alatae has parasite killing, antibacterial and antiseptical effect.
Folium Isatidis: bitter in the mouth, cold in nature. GUIXIN, stomach warp. Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing. Join the army for pathogenic warmth, unconsciousness due to high fever, send out speckle dermexanthesis, jaundice, hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.
Folium eucalypti globueli (Eucalyptus globulus Labill.): acrid in the mouth, hardship, cold in nature; Return lung, stomach, spleen, Liver Channel. Dispelling wind to relieve the exterior syndrome, heat-clearing and toxic substances removing, phlegm-eliminiating and qi-regulating, killing parasites for relieving itching. Main flu, high dyspnea of heat type is coughed, pertussis, abdominal distention, diarrhoea, dysentery, hook, filaricide, malaria, rheumatalgia, eczema, scabies, burn and scald, traumatic hemorrhage. Li Chenghu " pharmacognosy " carries: " decocting liquid controls erysipelas and other infectiousness pyesises. " modern medicine study confirmation, from Eucalyptus globulus Labill, isolate a kind of material with column chromatography, gram-positive bacterium is had inhibitory action, in vitro clostridium tetani and diphtheria corynebacterium toxin is had detoxicating adhesive.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature; Attach to the lung and stomach meridians. Expelling wind and cold, sensible pain relieving, detumescence and apocenosis, dampness leukorrhagia stopping. Profit blood vessels, expelling wind and cold, eliminating dampness and dredging channels, it is widely used in the treatment of the diseases such as soft tissue contusion, hyperosteogeny, muscular strain, rheumatic myositis, fracture, costal chondritis, scapulohumeral periarthritis, intercostal neuralgia. Escherichia coli, dysentery bacterium, Bacillus proteus, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, vibrio cholera, Bacillus tuberculosis etc. are all had inhibitory action by the Radix Angelicae Dahuricae.
Cortex Magnoliae Officinalis: bitter in the mouth, pungent, warm in nature; Return spleen, stomach, large intestine channel. Circulation of qi promoting removing food stagnancy, dampness is removed full, lowering the adverse QI to relieve asthma. Main stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant stops up QI rising in reverse order, and fullness in the chest is breathed with cough. Modern medicine study confirms, streptococcus pneumoniae, diphtheria corynebacterium, Hemolytic streptococcus, bacillus subtilis, will Hayes and Amur dysentery bacterium, staphylococcus aureus etc., in test tube, are had bacteriostasis by Cortex Magnoliae Officinalis decoct.
Radix Tripterygii Wilfordii: bitter in the mouth, property is pungent, greatly poison. GUIXIN, Liver Channel. Expelling wind and removing dampness; Promoting blood circulation to remove obstruction in the collateral; Reducing swelling and alleviating pain; Parasite killing detoxifies. Main classes rheumatic arthritis; Rheumatic arthritis; Glomerulonephritis; Nephrotic syndrome; Lupus erythematosus; Mouth xerophthalmia scheorma syndrome; Behcet disease; Eczema; Psoriasis; Leprosy; Scabies; Stubborn dermatitis.
Fructus glochidionis puberi(Herba Glochidii Puberi): bitter in the mouth, cool in nature, slightly poisonous; Return kidney channel. Removing damp-heat, resolving toxin and disinhibiting the throat, promoting flow of QI and blood. Cure mainly dysentery, have loose bowels, jaundice, malaria, stranguria with turbid discharge, leukorrhagia, laryngopharynx swelling and pain, toothache, colic, puerperal abdonimal pain. Modern medicine study confirms, 9 kinds of intestinal such as shigella, paratyphoid bacillus A and Salmonella typhi are had inhibitory action by Folium glochidionis puberi decoct, wherein most sensitive to congratulating dysentery bacterium.
Radix Sophorae Flavescentis: for the dry root of leguminous plant Radix Sophorae Flavescentis, spring, season in autumn two excavate, removes root head and little supporting root, cleaning, drying, or takes advantage of fresh slices, dry. It is bitter, cold. There are heat clearing and damp drying, parasite killing, the merit of diuresis. For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.
Flos Lonicerae: Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times. Its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and do not injure one's stomach, fragrance thoroughly reaches and can be eliminating evil. Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile diseases, such as fever of the body, dermexanthesis, send out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal effect is notable, and its effect is mainly heat-clearing and toxic substances removing, cures mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc. Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, various pathogens and the upper respiratory tract infection Causative viruss etc. such as Hemolytic streptococcus, tuberculosis stalk bacterium there is stronger restraint, additionally also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, can be used for treating respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 with other medicines compatibility and plant disease.
Fructus Gleditsia: the pod of Gleditsia officinalis, seed, scolus etc. all can be used as medicine, pod be used as medicine can eliminate the phlegm, diuresis; Seed is used as medicine and can control tinea and relieving constipation is secret; Spina Gleditsiae is used as medicine and can invigorate blood circulation and control skin ulcer tinea, and Gleditsia officinalis is used as medicine with fruit, seed. Fructus Gleditsia is containing triterpenoid saponin (gledinin, gleditschiasaponin), tannin, ceryl alcohol, nonacosane, stigmasterol, sitosterol etc. The function have eliminating the phlegm, having one's ideas straightened out. Saponin element contained in Fructus Gleditsia is triterpene class and oligosaccharide, has antiinflammatory, antiulcer, disease-resistant change effect, also has anticancer and improves the effects such as acquired immune deficiency syndrome (AIDS) immunity.
Flos Chrysanthemi Indici: Flos Chrysanthemi Indici is Compositae herbaceos perennial, and the capitate profile of Flos Chrysanthemi Indici is similar to Flos Chrysanthemi, wild in wild areas such as patana, Tian Bian, roadsides. It is preferred without stalk, complete, toil, the non-standard-sized sheet person of flower with yellow skin. Flos Chrysanthemi Indici cold nature, has dispelling wind and heat pathogens, subduing swelling and detoxicating. The diseases such as furuncle carbuncle, laryngopharynx swelling and pain, wind-fire acute conjunctivitis, headache dizziness can be treated. Function: detumescence. To staphylococcus aureus, diphtheria corynebacterium, streptococcus, bacillus pyocyaneus, puncture Shigella, influenza virus, all there is inhibitory action.
Fructus Arctii: nature and flavor: pungent, bitter, cold; Gui Jing: return lung stomach warp. Function: anemopyretic cold, epidemic febrile disease from the beginning of; Wind heat or cough due to lung-heat, cough up phlegm not smooth; Laryngopharynx swelling and pain; Macule is not saturating; At the measles initial stage, rash goes out not smooth and rubella pruritus; Sore swollen toxin and mumps etc. Raw with can loosening bowel to relieve constipation, pyretic toxicity red swelling and pain of throat, have constipation with heat retention concurrently especially suitable. For heat and toxic materials clearing away medicine compatibilities such as the not yet routed person of hot carbuncle toxin, normal and Herba Violae, Flos Chrysanthemi Indicis.
A kind of clinical laboratory of the present invention is suitable with medical material compatibility selected by sterilizing Chinese medicine preparation, meet Chinese medicine and modern medicine is theoretical, there is the effects such as heat-clearing and toxic substances removing, bacteriostasis and sterilization, parasite killing antiinflammatory, and human body skin is non-stimulated, safe without toxic side effect, can be widely applied to clinical laboratory's personnel's skin, medical apparatus and instruments and the sterilization to indoor environment, improves the work efficiency of clinical laboratory personnel, ensure that the accuracy rate of assay, should be widely promoted application.
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with embodiment, technical scheme is clearly and completely described. Obviously, described embodiment is the part of the present invention, rather than whole embodiments. Based on described embodiments of the invention, the every other embodiment that those of ordinary skill in the art obtain under the premise without creative work, broadly fall into the scope of protection of the invention.
Embodiment 1:
The raw material of a kind of clinical laboratory sterilizing Chinese medicine preparation of the present invention forms and weight is:
Herba Galii Teneri 6 grams, Herba goodyearae repentis 8 grams, Herba Celosiae argenteae 3 grams, little Herba Portulacae 15 grams, Spina Gleditsiae 5 grams, Herba Violae 3 grams, Herba pteridis vittatae 5 grams, Spica Prunellae 12 grams, Radix Zanthoxyli 16 grams, Rhizoma Osmundae 3 grams, Herba Artemisiae Annuae 12 grams, Rhizoma Donacis canniformis 10 grams, Herba Taraxaci 5 grams, Fructus rhois chinensis 16 grams, Herba Polycarpaeae Corymbosae 10 grams, Folium Artemisiae Argyi 8 grams, Codium fragile (Sur.) Har. 10 grams, Herba Emiliae 15 grams, 3 grams of Bulbus Allii, Radix et Caulis Opuntiae Dillenii 8 grams, ligustrum sinense 5 grams, Herba Laggerae Alatae 1 gram, Folium Isatidis 12 grams, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 grams, the Radix Angelicae Dahuricae 9 grams, Cortex Magnoliae Officinalis 15 grams, Radix Tripterygii Wilfordii 15 grams, Fructus glochidionis puberi(Herba Glochidii Puberi) 8 grams, Radix Sophorae Flavescentis 5 grams, Flos Lonicerae 3 grams, 14 grams of Fructus Gleditsia, Flos Chrysanthemi Indici 9 grams, Fructus Arctii 6 grams.
The preparation method of the Chinese medicine preparation of the present invention, comprises the steps:
(1) take Folium Isatidis, Bulbus Allii, Herba Galii Teneri, Radix et Caulis Opuntiae Dillenii and little Herba Portulacae strand juice, filter impurity, stay juice, standby;
(2) Flos Chrysanthemi Indici, Flos Lonicerae, Herba Emiliae, Herba Laggerae Alatae, Cortex Magnoliae Officinalis, Spina Gleditsiae, Herba pteridis vittatae, Spica Prunellae, Radix Zanthoxyli, the Radix Angelicae Dahuricae, Radix Tripterygii Wilfordii and Rhizoma Donacis canniformis decontamination are cleaned, it is placed in container, add the distilled water immersion of 8-10 times amount after 5-6 hour, boil 3-4 hour, extract; Again add 5-7 times amount distilled water, boil 2-3 hour, extract; Finally, add 2-4 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, obtain filtrate, standby;
(3) Folium Artemisiae Argyi, Fructus Arctii, Codium fragile (Sur.) Har., Herba Celosiae argenteae, Herba Violae, Rhizoma Osmundae, Fructus glochidionis puberi(Herba Glochidii Puberi) and Herba Artemisiae Annuae are smashed it is subsequently adding ethanol, sealing is placed in shady and cool ventilation place and stands 5-7 days, filtering, filtering residue adds water boiled with high heat, changes slow fire and adds thermal distillation 1-2 hour, volatile oil and water is made together to distill, collect distillate, stand 50-70 minute, distillate is cooled to room temperature, take upper strata fluid, obtain volatile oil stand-by;
(4) Radix Sophorae Flavescentis, Fructus Gleditsia, Herba Taraxaci, ligustrum sinense, Fructus rhois chinensis, Herba goodyearae repentis being cleaned chopping, with 3-8 times amount 80% ethanol, with the speed diafiltration of 3ml/min, filtered by percolate, filtrate is stand-by;
(5) by Folium eucalypti globueli (Eucalyptus globulus Labill.) and Herba Polycarpaeae Corymbosae decontamination, clean, be placed in frying pan, heat with slow fire, fry and be advisable to micro-the changing of coat tablets, take out airing, be placed in mortar, grind into powder, obtained the fine powder of 120 orders, standby;
(6) juice that step (1) is prepared, the filtrate that step (2), (4) prepare, the volatile oil of step (3) gained, after the fine powder mixing that step (5) prepares, the distilled water adding 10-12 times amount stirs, heated and boiled 0.5 hour, standing 1 hour, extraction filters to get filtrate, and filtrate fill is sealed up for safekeeping, 122 DEG C of-125 DEG C of pressure sterilizings 20-30 minute, Ji get clinical laboratory sterilizing Chinese medicine preparation.
Embodiment 2:
The raw material of a kind of clinical laboratory sterilizing Chinese medicine preparation of the present invention forms and weight is:
Herba Galii Teneri 4 grams, Herba goodyearae repentis 10 grams, Herba Celosiae argenteae 4 grams, little Herba Portulacae 13 grams, Spina Gleditsiae 6 grams, Herba Violae 4 grams, Herba pteridis vittatae 8 grams, Spica Prunellae 16 grams, Radix Zanthoxyli 10 grams, Rhizoma Osmundae 8 grams, Herba Artemisiae Annuae 5 grams, Rhizoma Donacis canniformis 5 grams, Herba Taraxaci 10 grams, Fructus rhois chinensis 13 grams, Herba Polycarpaeae Corymbosae 7 grams, Folium Artemisiae Argyi 13 grams, Codium fragile (Sur.) Har. 5 grams, Herba Emiliae 9 grams, 7 grams of Bulbus Allii, Radix et Caulis Opuntiae Dillenii 10 grams, ligustrum sinense 3 grams, Herba Laggerae Alatae 3 grams, Folium Isatidis 17 grams, Folium eucalypti globueli (Eucalyptus globulus Labill.) 12 grams, the Radix Angelicae Dahuricae 4 grams, Cortex Magnoliae Officinalis 20 grams, Radix Tripterygii Wilfordii 10 grams, Fructus glochidionis puberi(Herba Glochidii Puberi) 12 grams, Radix Sophorae Flavescentis 2 grams, Flos Lonicerae 7 grams, 11 grams of Fructus Gleditsia, Flos Chrysanthemi Indici 15 grams, Fructus Arctii 3 grams.
The preparation method of the Chinese medicine preparation of the present invention is with embodiment 1.
Embodiment 3:
The raw material of a kind of clinical laboratory sterilizing Chinese medicine preparation of the present invention forms and weight is:
Herba Galii Teneri 5 grams, Herba goodyearae repentis 12 grams, Herba Celosiae argenteae 3 grams, little Herba Portulacae 12 grams, Spina Gleditsiae 9 grams, Herba Violae 4 grams, Herba pteridis vittatae 7 grams, Spica Prunellae 13 grams, Radix Zanthoxyli 13 grams, Rhizoma Osmundae 6 grams, Herba Artemisiae Annuae 9 grams, Rhizoma Donacis canniformis 6 grams, Herba Taraxaci 6 grams, Fructus rhois chinensis 14 grams, Herba Polycarpaeae Corymbosae 5 grams, Folium Artemisiae Argyi 10 grams, Codium fragile (Sur.) Har. 6 grams, Herba Emiliae 10 grams, 5 grams of Bulbus Allii, Radix et Caulis Opuntiae Dillenii 13 grams, ligustrum sinense 4 grams, Herba Laggerae Alatae 2 grams, Folium Isatidis 13 grams, Folium eucalypti globueli (Eucalyptus globulus Labill.) 7 grams, the Radix Angelicae Dahuricae 5 grams, Cortex Magnoliae Officinalis 18 grams, Radix Tripterygii Wilfordii 11 grams, Fructus glochidionis puberi(Herba Glochidii Puberi) 9 grams, Radix Sophorae Flavescentis 4 grams, Flos Lonicerae 6 grams, 12 grams of Fructus Gleditsia, Flos Chrysanthemi Indici 13 grams, Fructus Arctii 4 grams.
The preparation method of the Chinese medicine preparation of the present invention is with embodiment 1.
1. toxicity test:
Acute oral is tested: choosing the NIH mice 40 of quality 22-25g, SPF level, male and female half and half, the Chinese medicine preparation per os gastric infusion embodiment of the present invention 1 prepared, administration is observed 15 days, records the various performance of mice and death condition every day, calculates LD. value.
Cumulative toxicity test: choose the NIH mice 40 of quality 22-25g, SPF level, male and female half and half, the Chinese medicine preparation per os gastric infusion that the embodiment of the present invention 1 prepares, dosage tests the LD. value drawn according to acute oral, the 1-4 days, it is administered 0.1LD. every time, within later every four hours, is incremented by 1.5 multiple doses, is administered 30 days, and weigh once in every four hours, calculate cumulative coefficient.
, there is not death in result: no abnormality seen reaction after acute oral test mice perfusion, and after it is carried out dissection accordingly, tissue or internal organs have no and substantially have obvious abnormal change.
After cumulative toxicity test is administered 20 days, male and female mice all occurs without death condition, and mice cumulative coefficient 5, for weak cumulative toxicity.
2. Ocular irritation test:
Select healthy white rabbit 12, weight 2.5-2.8kg, it is divided into three groups of A, B, C, often group 4, embodiment of the present invention 1-3 Chinese medicine preparation stock solution 0.1ml is respectively dropped into A, B, C of being corresponding in turn to and respectively organizes in rabbit conjunctiva of left eye capsule, with normal saline flushing after passive Guan Bi 4s, right eye instills normal saline as comparison. Observe rabbit 6 hours, 24 hours, 48 hours and 72 hours interior eyes localized variation.
Result: each group rabbit contamination group cornea and iris are normal, and conjunctiva has no edema, and having slight hyperemia, conjunctiva stimulation index is 1, by acute ocular stimulus intensity analytic intensity grade scale, belongs to nonirritant.
3. irritation test:
Select healthy white rabbit 12, weight 2.8-3.0kg, be divided into three groups of A, B, C, often group 4, lose hair or feathers respectively 3.0cm × 3.0cm by family's rabbit back spinal column both sides, does not damage epidermis, after 24 hours, 0.2ml embodiment of the present invention 1-3 Chinese medicine preparation stock solution uniform application respectively is respectively organized at A, B, C of being corresponding in turn to the left side of baring skin, right side is not smeared as comparison, after 4 hours, skin wiping is clean, observe dermoreaction, carry out stimulating scoring.
Result: each group rabbit baring skin reacts there are no erythema and edema, and skin wound repair integrated value is 0, control sides skin no abnormality seen, by skin wound repair standards of grading, reaction integral mean value is 0, and disinfectant solution of the present invention is to no skin irritation.
4. stability test:
Take the embodiment of the present invention 1-3 each 50ml of Chinese medicine preparation stock solution, after placing 90 days under 37 DEG C of conditions, for staphylococcus aureus is sterilized, before its killing effect and storage, compare no significant difference.
5. bacteriostatic test
Below the embodiment of the present invention 1 Chinese medicine preparation stock solution is carried out bacteriostatic experiment:
Experimental strain: select the strain that laboratory is representative, staphylococcus aureus and bacillus pyocyaneus.
Bacterium culture medium: nutrient agar and nutrient broth medium.
Experiment classification: bacteriostatic experiment divides experimental group and matched group, experimental group selects the embodiment of the present invention 1 Chinese medicine preparation stock solution, and matched group selects lysol.
Specific experiment step:
(1) preparation of bacterium solution: above two strain is inoculated in respectively on two agar culture mediums, cultivate 24 hours under 370C, from above-mentioned agar culture medium, picking colonies typical is inoculated in two fresh nutrient broth mediums respectively respectively, under synthermal, cultivate 20-24 hour, standby;
(2) Example 1 Chinese medicine preparation stock solution and each 55ml of lysol, be respectively placed in cut-back tank, and it dilutes 25 times respectively, is split respectively in two containers by above two diluent solution, is placed under aseptic condition, standby;
(3) with aseptic nutrient broth, the experimental strain that above-mentioned steps (1) is supported 20-24 hour through nutrition broth cultivation being diluted 50 times respectively, every kind of strain is sub-packed in two culture dishs, respectively labelling matched group and experimental group;
(4) dilute solution of the two parts of embodiment of the present invention 1 Chinese medicine preparation stock solutions of above-mentioned steps (2) gained being respectively dropped into experimental group culture dish, two parts of lysol dilute solutions are respectively dropped into matched group culture dish.
Experimental observation is measured:
Above-mentioned experiment is observed, observes two groups of strains and measure strain revolution mark concrete outcome.
After observation is measured, above-mentioned culture dish is placed under aseptic condition and stands two days, after liquid to be sterilized volatilizees completely, follow the tracks of it has been observed that matched group bacterium colony continues breeding, and experimental group bacterium colony is unchanged.
Experimental result: the sterilizing ability of the experimental group embodiment of the present invention 1 Chinese medicine preparation stock solution is much larger than the sterilizing ability of matched group disinfectant solution, and all kinds of strain can be suppressed to continue breeding.
Last it is noted that above example is only in order to illustrate technical scheme, it is not intended to limit; Although the present invention being described in detail with reference to previous embodiment, it will be understood by those within the art that: the technical scheme described in foregoing embodiments still can be modified by it, or wherein portion of techniques feature is carried out equivalent replacement; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the scope of various embodiments of the present invention technical scheme.

Claims (5)

1. clinical laboratory's sterilizing Chinese medicine preparation, it is characterized in that: make described Chinese medicine preparation raw material composition and parts by weight be: Herba Galii Teneri 4-6 part, Herba goodyearae repentis 8-12 part, Herba Celosiae argenteae 3-4 part, little Herba Portulacae 12-15 part, Spina Gleditsiae 5-9 part, Herba Violae 3-4 part, Herba pteridis vittatae 5-8 part, Spica Prunellae 12-16 part, Radix Zanthoxyli 10-16 part, Rhizoma Osmundae 3-8 part, Herba Artemisiae Annuae 5-12 part, Rhizoma Donacis canniformis 5-10 part, Herba Taraxaci 5-10 part, Fructus rhois chinensis 13-16 part, Herba Polycarpaeae Corymbosae 5-10 part, Folium Artemisiae Argyi 8-13 part, Codium fragile (Sur.) Har. 5-10 part, Herba Emiliae 9-15 part, Bulbus Allii 3-7 part, Radix et Caulis Opuntiae Dillenii 8-13 part, ligustrum sinense 3-5 part, Herba Laggerae Alatae 1-3 part, Folium Isatidis 12-17 part, Folium eucalypti globueli (Eucalyptus globulus Labill.) 7-12 part, Radix Angelicae Dahuricae 4-9 part, Cortex Magnoliae Officinalis 15-20 part, Radix Tripterygii Wilfordii 10-15 part, Fructus glochidionis puberi(Herba Glochidii Puberi) 8-12 part, Radix Sophorae Flavescentis 2-5 part, Flos Lonicerae 3-7 part, Fructus Gleditsia 11-14 part, Flos Chrysanthemi Indici 9-15 part, Fructus Arctii 3-6 part.
2. clinical laboratory according to claim 1 sterilizing Chinese medicine preparation, it is characterized in that: make described Chinese medicine composition raw material composition and parts by weight be: Herba Galii Teneri 6 parts, Herba goodyearae repentis 8 parts, Herba Celosiae argenteae 3 parts, little Herba Portulacae 15 parts, Spina Gleditsiae 5 parts, Herba Violae 3 parts, Herba pteridis vittatae 5 parts, Spica Prunellae 12 parts, Radix Zanthoxyli 16 parts, Rhizoma Osmundae 3 parts, Herba Artemisiae Annuae 12 parts, Rhizoma Donacis canniformis 10 parts, Herba Taraxaci 5 parts, Fructus rhois chinensis 16 parts, Herba Polycarpaeae Corymbosae 10 parts, Folium Artemisiae Argyi 8 parts, Codium fragile (Sur.) Har. 10 parts, Herba Emiliae 15 parts, 3 parts of Bulbus Allii, Radix et Caulis Opuntiae Dillenii 8 parts, ligustrum sinense 5 parts, Herba Laggerae Alatae 1 part, Folium Isatidis 12 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 10 parts, the Radix Angelicae Dahuricae 9 parts, Cortex Magnoliae Officinalis 15 parts, Radix Tripterygii Wilfordii 15 parts, Fructus glochidionis puberi(Herba Glochidii Puberi) 8 parts, Radix Sophorae Flavescentis 5 parts, Flos Lonicerae 3 parts, 14 parts of Fructus Gleditsia, Flos Chrysanthemi Indici 9 parts, Fructus Arctii 6 parts.
3. clinical laboratory according to claim 1 sterilizing Chinese medicine preparation, it is characterized in that: make described Chinese medicine composition raw material composition and parts by weight be: Herba Galii Teneri 4 parts, Herba goodyearae repentis 10 parts, Herba Celosiae argenteae 4 parts, little Herba Portulacae 13 parts, Spina Gleditsiae 6 parts, Herba Violae 4 parts, Herba pteridis vittatae 8 parts, Spica Prunellae 16 parts, Radix Zanthoxyli 10 parts, Rhizoma Osmundae 8 parts, Herba Artemisiae Annuae 5 parts, Rhizoma Donacis canniformis 5 parts, Herba Taraxaci 10 parts, Fructus rhois chinensis 13 parts, Herba Polycarpaeae Corymbosae 7 parts, Folium Artemisiae Argyi 13 parts, Codium fragile (Sur.) Har. 5 parts, Herba Emiliae 9 parts, 7 parts of Bulbus Allii, Radix et Caulis Opuntiae Dillenii 10 parts, ligustrum sinense 3 parts, Herba Laggerae Alatae 3 parts, Folium Isatidis 17 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 12 parts, the Radix Angelicae Dahuricae 4 parts, Cortex Magnoliae Officinalis 20 parts, Radix Tripterygii Wilfordii 10 parts, Fructus glochidionis puberi(Herba Glochidii Puberi) 12 parts, Radix Sophorae Flavescentis 2 parts, Flos Lonicerae 7 parts, 11 parts of Fructus Gleditsia, Flos Chrysanthemi Indici 15 parts, Fructus Arctii 3 parts.
4. clinical laboratory according to claim 1 sterilizing Chinese medicine preparation, it is characterized in that: make described Chinese medicine composition raw material composition and parts by weight be: Herba Galii Teneri 5 parts, Herba goodyearae repentis 12 parts, Herba Celosiae argenteae 3 parts, little Herba Portulacae 12 parts, Spina Gleditsiae 9 parts, Herba Violae 4 parts, Herba pteridis vittatae 7 parts, Spica Prunellae 13 parts, Radix Zanthoxyli 13 parts, Rhizoma Osmundae 6 parts, Herba Artemisiae Annuae 9 parts, Rhizoma Donacis canniformis 6 parts, Herba Taraxaci 6 parts, Fructus rhois chinensis 14 parts, Herba Polycarpaeae Corymbosae 5 parts, Folium Artemisiae Argyi 10 parts, Codium fragile (Sur.) Har. 6 parts, Herba Emiliae 10 parts, 5 parts of Bulbus Allii, Radix et Caulis Opuntiae Dillenii 13 parts, ligustrum sinense 4 parts, Herba Laggerae Alatae 2 parts, Folium Isatidis 13 parts, Folium eucalypti globueli (Eucalyptus globulus Labill.) 7 parts, the Radix Angelicae Dahuricae 5 parts, Cortex Magnoliae Officinalis 18 parts, Radix Tripterygii Wilfordii 11 parts, Fructus glochidionis puberi(Herba Glochidii Puberi) 9 parts, Radix Sophorae Flavescentis 4 parts, Flos Lonicerae 6 parts, 12 parts of Fructus Gleditsia, Flos Chrysanthemi Indici 13 parts, Fructus Arctii 4 parts.
5. the arbitrary described clinical laboratory's preparation method of sterilizing Chinese medicine preparation of claim 1-4, it is characterised in that comprise the steps:
(1) take Folium Isatidis, Bulbus Allii, Herba Galii Teneri, Radix et Caulis Opuntiae Dillenii and little Herba Portulacae strand juice, filter impurity, stay juice, standby;
(2) Flos Chrysanthemi Indici, Flos Lonicerae, Herba Emiliae, Herba Laggerae Alatae, Cortex Magnoliae Officinalis, Spina Gleditsiae, Herba pteridis vittatae, Spica Prunellae, Radix Zanthoxyli, the Radix Angelicae Dahuricae, Radix Tripterygii Wilfordii and Rhizoma Donacis canniformis decontamination are cleaned, it is placed in container, add the distilled water immersion of 8-10 times amount after 5-6 hour, boil 3-4 hour, extract; Again add 5-7 times amount distilled water, boil 2-3 hour, extract; Finally, add 2-4 times amount distilled water, heated and boiled 1-2 hour, extract; Merge three extracting solution, filter, obtain filtrate, standby;
(3) Folium Artemisiae Argyi, Fructus Arctii, Codium fragile (Sur.) Har., Herba Celosiae argenteae, Herba Violae, Rhizoma Osmundae, Fructus glochidionis puberi(Herba Glochidii Puberi) and Herba Artemisiae Annuae are smashed it is subsequently adding ethanol, sealing is placed in shady and cool ventilation place and stands 5-7 days, filtering, filtering residue adds water boiled with high heat, changes slow fire and adds thermal distillation 1-2 hour, volatile oil and water is made together to distill, collect distillate, stand 50-70 minute, distillate is cooled to room temperature, take upper strata fluid, obtain volatile oil stand-by;
(4) Radix Sophorae Flavescentis, Fructus Gleditsia, Herba Taraxaci, ligustrum sinense, Fructus rhois chinensis, Herba goodyearae repentis being cleaned chopping, with 3-8 times amount 80% ethanol, with the speed diafiltration of 3ml/min, filtered by percolate, filtrate is stand-by;
(5) by Folium eucalypti globueli (Eucalyptus globulus Labill.) and Herba Polycarpaeae Corymbosae decontamination, clean, be placed in frying pan, heat with slow fire, fry and be advisable to micro-the changing of coat tablets, take out airing, be placed in mortar, grind into powder, obtained the fine powder of 120 orders, standby;
(6) juice that step (1) is prepared, the filtrate that step (2), (4) prepare, the volatile oil of step (3) gained, after the fine powder mixing that step (5) prepares, the distilled water adding 10-12 times amount stirs, heated and boiled 0.5 hour, standing 1 hour, extraction filters to get filtrate, and filtrate fill is sealed up for safekeeping, 122 DEG C of-125 DEG C of pressure sterilizings 20-30 minute, Ji get clinical laboratory sterilizing Chinese medicine preparation.
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CN104998153A (en) * 2015-08-07 2015-10-28 张洪美 Sterilization disinfectant for clinical laboratory and preparation method thereof
CN105123816A (en) * 2015-10-20 2015-12-09 王明儒 Sterilizing and disinfecting liquid for clinical laboratory and preparation method

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106070379A (en) * 2016-06-29 2016-11-09 杨莉 A kind of for checking Traditional Chinese medicine disinfectant and the preparation method of apparatus sterilizing
CN106038934A (en) * 2016-07-07 2016-10-26 梁晓萍 Traditional Chinese medicine disinfectant for acupuncture
CN106109732A (en) * 2016-07-29 2016-11-16 山东大学齐鲁医院 A kind of antimicrobial body surface reagents and preparation method thereof
CN106818942A (en) * 2017-02-28 2017-06-13 殷雪华 A kind of Hospital Infection-Control Dept. sterilizing Chinese medicine composition
CN107875420A (en) * 2017-11-27 2018-04-06 广西协成日用化工有限公司 A kind of table-ware disinfection system
CN107996624A (en) * 2018-01-11 2018-05-08 宋瑞红 One kind examines apparatus disinfection solution and preparation method thereof

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