CN106177300A - A kind of medicine pill for pulmonary carcinoma auxiliary treatment and preparation method thereof - Google Patents

A kind of medicine pill for pulmonary carcinoma auxiliary treatment and preparation method thereof Download PDF

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CN106177300A
CN106177300A CN201610782750.8A CN201610782750A CN106177300A CN 106177300 A CN106177300 A CN 106177300A CN 201610782750 A CN201610782750 A CN 201610782750A CN 106177300 A CN106177300 A CN 106177300A
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parts
radix
rhizoma
herba
pulmonary carcinoma
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殷晓燕
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    • A61K9/20—Pills, tablets, discs, rods
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
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    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract

The invention discloses a kind of medicine pill for pulmonary carcinoma auxiliary treatment and preparation method thereof, by the Radix Astragali, Radix Salviae Miltiorrhizae, Stigma Croci, Flos phytolaccae, Radix Puerariae, Herba Peperomiae Dindygulensis, Herba Boeae Hygrometricae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Gentianae sarcorrhizae, Rhizoma Acori Graminei, the Cortex Eucommiae, Radix Clematidis, Caulis Spatholobi, Pheretima, Herba Epimedii, Radix Ilicis Pubescentis, Carapax et Plastrum Testudinis, Rhizoma nupharis pumili and Semen Lepidii (Semen Descurainiae) are prepared from, the each component of medicine is chosen by proportioning, first pulverize, grind to form smalls again, mix homogeneously, add alcohol reflux twice, merge twice extracting solution, again filter, vacuum evaporation is to thick paste, dextrin is added in thick paste, sucrose is packed after making pill.The causes of disease such as the lung cancer caused stagnation of QI, blood poly-, expectorant knot tired, wet are suited the remedy to the case by the present invention, have the effects such as invigorating blood circulation addiction, replenishing YIN and removing heat, heat-clearing and toxic substances removing, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, patient can be carried out whole body conditioning, improve the synthetic physical ability of patient.

Description

A kind of medicine pill for pulmonary carcinoma auxiliary treatment and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, a kind of medicine pill for pulmonary carcinoma auxiliary treatment and preparation side thereof Method.
Background technology
Pulmonary carcinoma betides bronchial mucosa epithelium, also known as bronchogenic carcinoma.Immediate and mid-term many countries all report sending out of pulmonary carcinoma Sick rate substantially increases, in male carcinoma patient, pulmonary carcinoma oneself rank first, increase the most rapidly at women sickness rate, account for women common The 2nd of malignant tumor or the 3rd.The cause of disease of pulmonary carcinoma is the clearest and the most definite, and great mass of data shows, smokes a cigarette the most in a large number It it is an important paathogenic factor of pulmonary carcinoma.
In doctor trained in Western medicine, pulmonary carcinoma is modal lung primary malignant tumor, and most pulmonary carcinoma originate from bronchial mucosa Epithelium, therefore also known as lung bronchogenic carcinoma.The optimal treatment mode of early-stage cancer is excision.Radical surgery the most thoroughly excises Big tumor focus, but patient body is after the strike of operation, the weakest, weakened immune system, and do not remove Minimal neoplastic focus may take advantage of the occasion grow up, easily cause the recurrence of cancer.So, it is not meant to after operative treatment that cancer is own Through curing, also need to carry out the auxiliary treatment means such as radiotherapy, chemotherapy, biological immune treatment, thoroughly remove cancerous cell, anti- Only pulmonary carcinoma, the recurrence of hepatocarcinoma.But at present the therapeutic effect of pulmonary carcinoma is unsatisfactory, operative treatment can be by cancer resection, but sometimes Bring postoperative dysfunction, and some new symptoms occur；Reaction and rear something lost phenomenon after radiotherapy are also apparent from； Chemotherapy also has significantly impact to digestive tract and hemopoietic system.
Summary of the invention
It is an object of the invention to provide a kind of medicine pill for pulmonary carcinoma auxiliary treatment and preparation method thereof, to solve The problem proposed in above-mentioned background technology.
For achieving the above object, the present invention provides following technical scheme:
A kind of for pulmonary carcinoma auxiliary treatment medicine pill, the crude drug of following weight portion be prepared from: the Radix Astragali 20～ 24 parts, Radix Salviae Miltiorrhizae 8～10 parts, Stigma Croci 28～32 parts, Flos phytolaccae 12～16 parts, Radix Puerariae 30～36 parts, Herba Peperomiae Dindygulensis 12～14 parts, cattle Auricled Hedyotis Herb 10～14 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 18～22 parts, Radix Gentianae sarcorrhizae 6～8 parts, Rhizoma Acori Graminei 7～9 parts, the Cortex Eucommiae 12～16 parts, Radix Clematidis 9～ 13 parts, Caulis Spatholobi 6～8 parts, Pheretima 4～6 parts, Herba Epimedii 11～13 parts, Radix Ilicis Pubescentis 6～8 parts, Carapax et Plastrum Testudinis 4～6 parts, Rhizoma nupharis pumili 5 ～7 parts, Semen Lepidii (Semen Descurainiae) 15～19 parts.
As the further scheme of the present invention: be specifically prepared from by the crude drug of following weight portion: the Radix Astragali 22 parts, Radix Salviae Miltiorrhizae 9 parts, Stigma Croci 30 parts, Flos phytolaccae 14 parts, Radix Puerariae 33 parts, Herba Peperomiae Dindygulensis 13 parts, Herba Boeae Hygrometricae 12 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 parts, Radix Gentianae sarcorrhizae 7 Part, Rhizoma Acori Graminei 8 parts, the Cortex Eucommiae 14 parts, Radix Clematidis 11 parts, Caulis Spatholobi 7 parts, Pheretima 5 parts, Herba Epimedii 12 parts, Radix Ilicis Pubescentis 7 parts, Carapax et Plastrum Testudinis 5 Part, Rhizoma nupharis pumili 6 parts, Semen Lepidii (Semen Descurainiae) 17 parts.
The preparation method of a kind of described medicine pill for pulmonary carcinoma auxiliary treatment, comprises the following steps: select by proportioning The each component of thing of getting it filled, first pulverizes, then grinds to form smalls, mix homogeneously, and the volume fraction feeding the mixture into 8～10 times is In the ethanol of 65%, heating and refluxing extraction 45～55min, after filtration, the volume fraction that filtering residue part adds 6～8 times is In the ethanol of 65%, heating and refluxing extraction 30～40min, merge twice extracting solution, again filter, vacuum evaporation is to relatively Density is the thick paste of 1.30～1.40, and in thick paste, addition dextrin, sucrose are packed after making pill.
Compared with prior art, the invention has the beneficial effects as follows:
The present invention selects medical material, and the property of medicine is suitable mutually auxiliary mutually, suits the medicine to the illness the causes of disease such as the lung cancer caused stagnation of QI, blood poly-, expectorant knot tired, wet Prescribe medicine, has the effects such as invigorating blood circulation addiction, replenishing YIN and removing heat, heat-clearing and toxic substances removing, and good absorbing effect is evident in efficacy, has no side effect and faces Bed untoward reaction, can carry out whole body conditioning to patient, improves the synthetic physical ability of patient.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only a part of embodiment of the present invention rather than whole embodiments.Based in the present invention Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under not making creative work premise, all Belong to the scope of protection of the invention.
Embodiment 1
For the medicine pill of pulmonary carcinoma auxiliary treatment, the crude drug of following weight portion it is prepared from: the Radix Astragali 20 parts, Radix Salviae Miltiorrhizae 10 parts, Stigma Croci 28 parts, Flos phytolaccae 16 parts, Radix Puerariae 30 parts, Herba Peperomiae Dindygulensis 14 parts, Herba Boeae Hygrometricae 10 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 22 parts, Radix Gentianae sarcorrhizae 6 Part, Rhizoma Acori Graminei 9 parts, the Cortex Eucommiae 12 parts, Radix Clematidis 13 parts, Caulis Spatholobi 6 parts, Pheretima 6 parts, Herba Epimedii 11 parts, Radix Ilicis Pubescentis 8 parts, Carapax et Plastrum Testudinis 4 Part, Rhizoma nupharis pumili 7 parts, Semen Lepidii (Semen Descurainiae) 15 parts.
The preparation process of above-mentioned medicine pill is as follows: chooses each component of medicine by proportioning, first pulverizes, then grinds to form thin End, mix homogeneously, feed the mixture in the ethanol that volume fraction is 65% of 8 times, heating and refluxing extraction 45min, after filtration, Filtering residue part is added in the ethanol that volume fraction is 65% of 6 times, heating and refluxing extraction 30min, merge twice extracting solution, Again filtering, vacuum evaporation to relative density is the thick paste of 1.30～1.40, and in thick paste, medicine made by addition dextrin, sucrose Pack after ball.
Embodiment 2
For the medicine pill of pulmonary carcinoma auxiliary treatment, the crude drug of following weight portion it is prepared from: the Radix Astragali 22 parts, Radix Salviae Miltiorrhizae 9 parts, Stigma Croci 30 parts, Flos phytolaccae 14 parts, Radix Puerariae 33 parts, Herba Peperomiae Dindygulensis 13 parts, Herba Boeae Hygrometricae 12 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 parts, Radix Gentianae sarcorrhizae 7 Part, Rhizoma Acori Graminei 8 parts, the Cortex Eucommiae 14 parts, Radix Clematidis 11 parts, Caulis Spatholobi 7 parts, Pheretima 5 parts, Herba Epimedii 12 parts, Radix Ilicis Pubescentis 7 parts, Carapax et Plastrum Testudinis 5 Part, Rhizoma nupharis pumili 6 parts, Semen Lepidii (Semen Descurainiae) 17 parts.
The preparation process of above-mentioned medicine pill is as follows: chooses each component of medicine by proportioning, first pulverizes, then grinds to form thin End, mix homogeneously, feed the mixture in the ethanol that volume fraction is 65% of 9 times, heating and refluxing extraction 50min, after filtration, Filtering residue part is added in the ethanol that volume fraction is 65% of 7 times, heating and refluxing extraction 35min, merge twice extracting solution, Again filtering, vacuum evaporation to relative density is the thick paste of 1.30～1.40, and in thick paste, medicine made by addition dextrin, sucrose Pack after ball.
Embodiment 3
For the medicine pill of pulmonary carcinoma auxiliary treatment, the crude drug of following weight portion it is prepared from: the Radix Astragali 24 parts, Radix Salviae Miltiorrhizae 8 parts, Stigma Croci 32 parts, Flos phytolaccae 12 parts, Radix Puerariae 36 parts, Herba Peperomiae Dindygulensis 12 parts, Herba Boeae Hygrometricae 14 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 18 parts, Radix Gentianae sarcorrhizae 8 Part, Rhizoma Acori Graminei 7 parts, the Cortex Eucommiae 16 parts, Radix Clematidis 9 parts, Caulis Spatholobi 8 parts, Pheretima 4 parts, Herba Epimedii 13 parts, Radix Ilicis Pubescentis 6 parts, Carapax et Plastrum Testudinis 6 Part, Rhizoma nupharis pumili 5 parts, Semen Lepidii (Semen Descurainiae) 19 parts.
The preparation process of above-mentioned medicine pill is as follows: chooses each component of medicine by proportioning, first pulverizes, then grinds to form thin End, mix homogeneously, feed the mixture in the ethanol that volume fraction is 65% of 10 times, heating and refluxing extraction 55min, filters After, filtering residue part is added in the ethanol that volume fraction is 65% of 8 times, heating and refluxing extraction 40min, merge twice extraction Liquid, filters again, and vacuum evaporation to relative density is the thick paste of 1.30～1.40, adds dextrin, sucrose system in thick paste Pack after becoming pill.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of the spirit or essential attributes of the present invention, it is possible to realize the present invention in other specific forms.Therefore, no matter From the point of view of which point, all should regard embodiment as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit requires rather than described above limits, it is intended that all by fall in the implication of equivalency and scope of claim Change is included in the present invention.

Claims (3)

1. the medicine pill for pulmonary carcinoma auxiliary treatment, it is characterised in that be prepared from by the crude drug of following weight portion: The Radix Astragali 20～24 parts, Radix Salviae Miltiorrhizae 8～10 parts, Stigma Croci 28～32 parts, Flos phytolaccae 12～16 parts, Radix Puerariae 30～36 parts, Herba Peperomiae Dindygulensis 12 ～14 parts, Herba Boeae Hygrometricae 10～14 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 18～22 parts, Radix Gentianae sarcorrhizae 6～8 parts, Rhizoma Acori Graminei 7～9 parts, the Cortex Eucommiae 12～16 parts, Radix Clematidis 9～13 parts, Caulis Spatholobi 6～8 parts, Pheretima 4～6 parts, Herba Epimedii 11～13 parts, Radix Ilicis Pubescentis 6～8 parts, Carapax et Plastrum Testudinis 4～6 parts, Rhizoma nupharis pumili 5～7 parts, Semen Lepidii (Semen Descurainiae) 15～19 parts.
Medicine pill for pulmonary carcinoma auxiliary treatment the most according to claim 1, it is characterised in that specifically by following weight The crude drug of part is prepared from: the Radix Astragali 22 parts, Radix Salviae Miltiorrhizae 9 parts, Stigma Croci 30 parts, Flos phytolaccae 14 parts, Radix Puerariae 33 parts, Herba Peperomiae Dindygulensis 13 Part, Herba Boeae Hygrometricae 12 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20 parts, Radix Gentianae sarcorrhizae 7 parts, Rhizoma Acori Graminei 8 parts, the Cortex Eucommiae 14 parts, Radix Clematidis 11 parts, Caulis Spatholobi 7 parts, ground Dragon 5 parts, Herba Epimedii 12 parts, Radix Ilicis Pubescentis 7 parts, Carapax et Plastrum Testudinis 5 parts, Rhizoma nupharis pumili 6 parts, Semen Lepidii (Semen Descurainiae) 17 parts.
3. a preparation method for the medicine pill for pulmonary carcinoma auxiliary treatment as claimed in claim 1 or 2, its feature exists In, comprise the following steps: choose each component of medicine by proportioning, first pulverize, then grind to form smalls, mix homogeneously, will mixing Thing adds in the ethanol that volume fraction is 65% of 8～10 times, and heating and refluxing extraction 45～55min, after filtration, by filtering residue part Add in the ethanol that volume fraction is 65% of 6～8 times, heating and refluxing extraction 30～40min, merge twice extracting solution, again Filtering, vacuum evaporation to relative density is the thick paste of 1.30～1.40, after in thick paste, pill made by addition dextrin, sucrose Packaging.
CN201610782750.8A 2016-08-31 2016-08-31 A kind of medicine pill for pulmonary carcinoma auxiliary treatment and preparation method thereof Pending CN106177300A (en)

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CN103432401A (en) * 2013-08-20 2013-12-11 梁世杰 Traditional Chinese medicine powder prepared from three flowers, five seeds and six whites for treating lung cancer
CN103705847A (en) * 2013-12-19 2014-04-09 太仓市伟基生物科技有限公司 Lung cancer traditional Chinese medicinal fumigation prescription for adjuvant chemotherapy
CN104524374A (en) * 2014-12-30 2015-04-22 潘振奎 Traditional Chinese medicine formula for treating lung cancer and preparation method of traditional Chinese medicine formula

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Publication number Priority date Publication date Assignee Title
CN103432401A (en) * 2013-08-20 2013-12-11 梁世杰 Traditional Chinese medicine powder prepared from three flowers, five seeds and six whites for treating lung cancer
CN103705847A (en) * 2013-12-19 2014-04-09 太仓市伟基生物科技有限公司 Lung cancer traditional Chinese medicinal fumigation prescription for adjuvant chemotherapy
CN104524374A (en) * 2014-12-30 2015-04-22 潘振奎 Traditional Chinese medicine formula for treating lung cancer and preparation method of traditional Chinese medicine formula

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孙易娜: "中西医结合治疗非小细胞肺癌临床研究概况", 《湖北中医药大学学报》 *

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