CN103432401A - Traditional Chinese medicine powder prepared from three flowers, five seeds and six whites for treating lung cancer - Google Patents
Traditional Chinese medicine powder prepared from three flowers, five seeds and six whites for treating lung cancer Download PDFInfo
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Abstract
Traditional Chinese medicine powder prepared from three flowers, five seeds and six whites for treating lung cancer comprises the following components by weight: 25 parts of tibetan snow lotus, 25 parts of honeysuckle, 25 parts of saffron, 20 parts of gallnut, 20 parts of semen lepidii, 20 parts of poison nut, 20 parts of shizandra berry, 20 parts of radix semiaquilegiae, 15 parts of atractylis ovata, 15 parts of bletilla striata, 15 parts of white mulberry root-bark, 15 parts of bittersweet herb, 15 parts of spreading hedyotis herb, 15 parts of alum, 10 parts of scorpion tails, 10 parts of centipede and 10 parts of stir-baked squama manitis. The Traditional Chinese medicine powder prepared from the three flowers, the five seeds and the six whites provided by the invention has an obvious clinical curative effect on treating lung cancer or lung tumor, is obvious in curative effect, has no toxic or side effect, is simple and safe in therapeutic process, reduces pain of a patient, lowers the treatment cost, and greatly prolongs the patient life.
Description
Technical field
The present invention relates to Chinese medicine compound and application thereof, special, relate to a kind of Chinese medicine three that is used for the treatment of pulmonary carcinoma and spend five sons six loose in vain, and the application aspect treatment pulmonary carcinoma.
Background technology
Malignant tumor becomes the 21 century mankind's No.1 Health Killer, and WTO expects will have 1,700 ten thousand people to die from cancer the year two thousand thirty in global every year.And the whole world is annual is diagnosed as cancer over 1,200 ten thousand people.The annual newly-increased cancer mortality number 1,500,000 in inland of China, account for 20% of the whole world.And pulmonary carcinoma occupies global cancer first place always, the treatment of pulmonary carcinoma is the emphasis that global medical circle is paid close attention to always.The advantage of Chinese Traditional Medicine in cancer treatment procedure admitted by medical circle gradually, becomes the radiotherapy that continues, chemotherapy, and the fourth-largest anticancer means beyond operation, and the status in anticancer therapy is got over important.
Pulmonary carcinoma belongs to the traditional Chinese medical science " lung cellulitis ", " pulmonary distension ", " lump in the right hypochondrium ", " lump at the right hypochondrium " category, due to human righteousness's weakness, and imbalance of YIN and YANG, evil poison is taken advantage of a weak point in opponent's defence and is invaded, and causes visceral dysfunction, the stagnation of QI, expectorant knot, blood stasis, poison is poly-, with the passing of time forms lump.For patients with lung cancer, gas, expectorant, the stasis of blood, poison, be pathological product, is also paathogenic factor, and simulataneous insufficiency and excessive, so that heresy is simultaneously contained and just damaged.
For the Chinese pathology characteristics of pulmonary carcinoma, need to develop a kind of Chinese medicine that can treat pulmonary carcinoma, it can produce good curative effect for the etiology and pathogenesis characteristics of pulmonary carcinoma.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine three for the treatment of pulmonary carcinoma and spend five sons six loose in vain, aspect treatment pulmonary carcinoma and lung tumors, there is good curative effect, no side effects.
According to an aspect of the present invention, provide a kind of Chinese medicine three for the treatment of pulmonary carcinoma to spend five sons six loose in vain, it comprises the component of following mass fraction: Saussurea involucrata Kar. et Kir. et Maxim. is spent 25 parts, 25 parts of Flos Loniceraes, 25 parts of Stigma Crocis, 20 parts of Galla Chinensiss, 20 parts of Semen Lepidii (Semen Descurainiae)s, 20 parts of Semen Strychni, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Radix Semiaquilegiaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Cortex Mori, 15 parts of Herba Solani Lyratis, 15 parts of Herba Hedyotidis Diffusaes, 15 parts of Alumens, 10 parts, scorpion tail, 10 parts of Scolopendras, 10 parts of stir-baked SQUAMA MANITISs.
Preferably, the present invention three spends the white component dosage that falls apart courses for the treatment of of five sons six to be: Saussurea involucrata Kar. et Kir. et Maxim. flower 25g, Flos Lonicerae 25g, Stigma Croci 25g, Galla Chinensis 20g, Semen Lepidii (Semen Descurainiae) 20g, Semen Strychni 20g, Fructus Schisandrae Chinensis 20g, Radix Semiaquilegiae 20g, Rhizoma Atractylodis Macrocephalae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Cortex Mori 15g, Herba Solani Lyrati 15g, Herba Hedyotidis Diffusae 15g, Alumen 15g, scorpion tail 10g, Scolopendra 10g, stir-baked SQUAMA MANITIS 10g.
According to a further aspect in the invention, provide a kind of Chinese medicine three for the treatment of pulmonary carcinoma to spend five son six white loose preparation technologies, comprised the steps: to spend 25 parts of 25 parts, 25 parts of Flos Loniceraes and Stigma Crocis to dry in the shade Saussurea involucrata Kar. et Kir. et Maxim.; 20 portions of waters of Semen Strychni are cooked off to skin, and section is dried, and uses the Oleum Sesami burned to yellow skin; By 20 parts of Galla Chinensiss, 20 parts of Semen Lepidii (Semen Descurainiae)s, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Radix Semiaquilegiaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Cortex Mori, 15 parts of Herba Solani Lyratis, 15 parts of Herba Hedyotidis Diffusaes, 10 parts, scorpion tail, 10 parts of Scolopendras and 10 parts of oven dry of stir-baked SQUAMA MANITIS; Above-mentioned each medical material processed is mixed with 15 parts of Alumens; The mixture of above-mentioned each medical material is pulverized repeatedly with pulverizer, until reach the above medicated powder of 40 orders.
According to a further aspect in the invention, relating to aforementioned Chinese medicine three spends five sons six to be dispersed in vain for the preparation of the application in the product for the treatment of pulmonary carcinoma.
Chinese medicine preparation three of the present invention spends five sons six to be dispersed in vain treatment pulmonary carcinoma or the lung tumors aspect has obvious clinical efficacy, therapeutic effect is obvious, have no side effect, therapeutic process is simple and safe, adhere to oral getting final product, need not carry out traditional radiation and chemotherapy formality, reduce patient's misery and medical expense, greatly extend patient's life-span.
The specific embodiment
For making the purpose, technical solutions and advantages of the present invention more cheer and bright, below in conjunction with the specific embodiment, the present invention is described in more detail.Should be appreciated that, these descriptions are exemplary, and do not really want to limit the scope of the invention.In addition, in the following description, omitted the description to known technology, to avoid unnecessarily obscuring concept of the present invention.
The Chinese medicine that is used for the treatment of pulmonary carcinoma that the present invention proposes " three spend five sons six loose in vain " by name, the component that it comprises following mass fraction: Saussurea involucrata Kar. et Kir. et Maxim. is spent 25 parts, 25 parts of Flos Loniceraes, 25 parts of Stigma Crocis, 20 parts of Galla Chinensiss, 20 parts of Semen Lepidii (Semen Descurainiae)s, 20 parts of Semen Strychni, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Radix Semiaquilegiaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Cortex Mori, 15 parts of Herba Solani Lyratis, 15 parts of Herba Hedyotidis Diffusaes, 15 parts of Alumens, 10 parts, scorpion tail, 10 parts of Scolopendras, 10 parts of stir-baked SQUAMA MANITISs.
Below above-mentioned each component is carried out to traditional Chinese medical science pharmacology analysis.
Saussurea involucrata Kar. et Kir. et Maxim. flower, warm in nature, sweet in the mouth, hardship, enter spleen, kidney channel, and the cold relieving tonifying YANG is arranged, and the merit of removing toxic substances and promoting subsidence of swelling, regulating menstruation, hemostasis is applicable to positive QI-insufficiency, asthenia is thin and weak, carcinoma is sluggish, the diseases such as traumatic hemorrhage.The congenital the foundation of acquired constitution of flat benefit.
Flos Lonicerae, sweet in the mouth cold in nature, fragrant odour, return lung, stomach, heart channel.Merit is at heat-clearing and toxic substances removing, wind-heat dissipating, treatment of ulcer toxic swelling, carbuncle furuncle.Compendium of Material Medica is carried " Flos Lonicerae, be good at removing toxic substances, therefore control carbuncle, toxic swelling, skin ulcer tinea ... " " medical center is usurped the want-property of medicine " and is referred to as " persons particularly liable to develop skin infection's principal agent ".
Stigma Croci, cool in nature, sweet in the mouth, micro-hardship, the merit of thin channels and activating collaterals, stimulating the menstrual flow silt, scattered silt relieving accumulation of pathogens, reducing swelling and alleviating pain, removing pathogenic heat from blood and toxic substance from the body is arranged.Cure mainly, the chest and diaphragm painful abdominal mass is vexed, and ecchymosis swells and ache, and spits blood, and goes mad, frightened fear in a trance disease.
According to modern pharmacological research, above-mentioned three medical materials all have the active component of powerful kill cancer cell.Crocetin wherein, crocin and Picrocrocin have stronger active anticancer.The DNA that its anticancer mechanism is anticancer and RNA are synthetic, suppress the expression of the kinase whose activity of cell protein and proto-oncogene; The Xuelianhuangtong compounds, and the Herba Saussureae Involueratae alkaloid has to DNA, RNA and the protein synthesis of cancerous cell the inhibitory action shown.Flos Lonicerae, in anticancer, can strengthen immune function of human body, promotes lymphocyte transformation, strengthens leukocytic phagocytic function.
Above three flavor medicines also claim " three flowers ", get the meaning of its " all flowers all rise ", light weight raises up, the canopy of through the five internal organs, attack the cancer poison and just do not hinder, detoxification and removing stasis and do not stay heresy, play eliminating toxic substances to remove stasis, mass dissipating and swelling eliminating jointly, dredging lung network, hemostasis by removing blood stasis, the effect of Certain cancer, can be used as the monarch drug of Chinese medicine preparation of the present invention.
Galla Chinensis is sour, salty, flat.Return liver,spleen,kidney, lung, large intestine channel.The merit anticancer, convergence lung qi, hemostasia and detumescence that relieves internal heat is arranged.Cure mainly chronic cough of deficiency lung, night sweat, the diseases such as toxic swelling.Record the effect of " cough-relieving is coughed for the pathogenic fire reducing of astringing the lung, the drink that reduces phlegm, and detumescence poison, holds back routed skin ulcer ... " according to Compendium of Material Medica.
Semen Strychni, bitter in the mouth is cold in nature, returns liver, spleen channel, and mass dissipating and swelling eliminating is arranged, removing obstruction in the collateral to relieve pain, anticancer merit of relievining asthma, cure mainly ulcer sore pain, the insensitive impediment numbness, chronic cough is panted.Have according to Compendium of Material Medica that " mass in the abdomen disappears." merit; According to " surgery is given birth to collection entirely ", record can " the expectorant poison that in peeling, film condenses outward.”
Semen Lepidii (Semen Descurainiae), bitter in the mouth, suffering, in Great Cold, return lung, urinary bladder channel, eliminating pathogen from the lung for relieving asthma, line water detumescence, cure mainly sputum and stop up lung, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, must not put down sleeping, the diseases such as ascites pleural fluid swollen, dysuria.According to Shennong's Herbal record “ Zhu lumps in the chest and abdomen stagnation of QI, the diet cold and heat, broken hard by evil, the tonneau water channel.”
Fructus Schisandrae Chinensis, sour, sweet, warm, supplementing QI for promoting the production of body fluid is arranged, the nourishing kidney of astringing the lung, the merit of the arresting seminal emission of calming the nerves, cure mainly the diseases such as chronic cough dyspnea due to deficiency, the few xerostomia in Tianjin, forgetful insomnia.According to Shennong's Herbal, put down in writing: " main QI invigorating, cough with dyspnea, the thin degree of impairment caused by overstrain, tonifying for the deficiency, reinforcing YIN-essence.”
Radix Semiaquilegiae, cold in nature, sweet in the mouth suffering, micro-hardship, return liver, spleen, urinary bladder channel, heat-clearing and toxic substances removing is arranged, relieving asthma, calm the frightened, dispersing swelling and dissipating binds, the merit of relieving stranguria by diuresis, cure mainly carbuncle, scrofula, the cough due to deficiency of the lung records according to another " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " loose all skin ulcers are swollen; attack carbuncle, the evacuation of pus analgesic therapy, control scrofula; dissipation tuberculosis ... breast carcinoma as hard as flint, clothes loose or routed ".
According to modern pharmacological research, above five tastes medical material all has the effect of direct or indirect kill cancer cell.Gallotannin can solidify and the former tannin of destruction of cancer cells, has antitumor action, and for example, to murine sarcoma S-180, the suppression ratio of human hela cell JTC-26 all reaches more than 90%.Semen Strychni has extensive antitumaous effect, as sarcoma S-180 and leukaemia are all had to antitumaous effect.Semiadoxoin A has stronger cytotoxic effect, effective to kinds cancer.It is worth mentioning that, the Fructus Schisandrae Chinensis effective ingredient, can increase antineoplastic agent accumulating in the drug-resistant tumor cell, greatly improves the sensitivity to anti-tumor medicine.Whole prescription is played to potentiation.
Above five kinds of Chinese medicine also claims " five sons ", gets the meaning of its " "the philosophers," referring to the philosophers or their works, outside the Confucianists all falls ", and matter heavily drops, the therapeutic method to keep the adverse QI flowing downwards of astringing the lung, and improving inspiration by invigorating kidney-QI is returned unit, and mothers and sons are joined, orderly and clearly mechanism of qi.Jointly play the pendant cancer and relieving asthma, by the expectorant diuretic, hardship is let out acid and is held back, and the effect of harmonizing the functional activities of vital QI can be used as the ministerial drug of Chinese medicine preparation of the present invention.
The Rhizoma Atractylodis Macrocephalae, warm in nature, bitter in the mouth, sweet, return spleen, the stomach warp.Air making-up and spleen enlivening, the dampness diuretic, anticancer.Cure mainly insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, the diseases such as the prolonged illness deficiency of vital energy.
The Pseudobulbus Bletillae (Rhizoma Bletillae), bitter, sweet, puckery, be slightly cold.Return lung, liver, stomach warp.Merit is in tonifying the lung, and hemostasis, subside a swelling, granulation promoting, and sore, cure mainly, and lung is hindered hemoptysis, epistaxis, incised wound is hemorrhage, swollen ulcer drug, ulcer pain.According to " the southern regions of the Yunnan Province book on Chinese herbal medicine ", record: " control consumptive disease impairing the lung gas, tonifying the lung void, cough-relieving is coughed, the pulmonary tuberculosis that disappears hemoptysis, the convergence lung " merit.And " herbal classic " has: " main carbuncle malignant boil loses cellulitis, the dead flesh of impairment of YIN.”
Cortex Mori, sweet; Hot; Cold in nature, return lung; Spleen channel.Eliminating pathogen from the lung for relieving asthma; Inducing diuresis to remove edema, cure mainly lung-heat and breathe heavily expectorant; Diseases caused by retention of fluid stops lung; The distension dyspnea with rapid respiration, have " sweet with the deficiency of reinforcing premodial qi tonify deficiency, hot having a surplus and antitussive with eliminating the pathogens from the lung gas." good reputation.
Herba Solani Lyrati, hardship, flat, clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, anticancer.
Herba Hedyotidis Diffusae, bitter, sweet, cold.Return stomach, large intestine, small intestine meridian.Heat-clearing and toxic substances removing, dampness removing is treating stranguria, anticancer.Cure mainly carbuncle sore tumefacting virus, cancerous protuberance pain.
Alumen, cold in nature, sour-puckery flavor, return lung, liver, spleen, large intestine channel, anticancer, the dampness detumescence of relieving internal heat, astringing to arrest bleeding, the expectorant of dispeling the wind.According to Compendium of Material Medica, put down in writing: " the dampness removing toxic substances, chase after saliva, the hemostasis analgesic therapy, and meat is disliked in erosion, gives birth to good meat, controls the carbuncle furuncle swollen, swollen ulcer drug malignant boil, the merit of brave dog snakes and scorpions hundred insect bites.”
According to modern pharmacological research, above Six-element medical material majority has the effect of kill cancer cell.The Rhizoma Atractylodis Macrocephalae has cytotoxicity to oncocyte, can reduce the rate of increase of oncocyte, lowers the aggressive of tumor tissue, improves the ability of body antitumor reaction; The Pseudobulbus Bletillae (Rhizoma Bletillae) contains the phlegmatic temperament polysaccharide, has antitumaous effect; The Herba Solani Lyrati anticancer effective component is the B-solamarine, is the broad-spectrum anticarcinogen; The contained number of chemical composition of Herba Hedyotidis Diffusae has inhibitory action to all kinds of cancers, and its extract energy activated T lymphocytes makes it discharge interferon, and the kill tumor cell, have the effect that strengthens the human body non-specific immunity; Alumen can impel cancer surrounding tissue fibrosis, vessel wall thickening, neointimal hyperplasia, thrombosis, and can produce a large amount of neutrophilic granulocytes, mononuclear cell, phagocyte and lymphocyte gathering, make the cancerous tissue necrosis, thereby play the growth of anticancer and the effect of transfer, active anticancer can reach 70%～90%.
Above Six-element medicine also claims " six is white ", the meaning of getting its " Bai Yiying lung ", and assistant principal drug assistance ministerial drug, play building up the spleen to supplement the lung, invigorating the spleen to benefit the lung, the granulation promoting primordial QI reinforcing, the merit of the anticancer analgesic therapy of reducing phlegm, can be used as the adjuvant drug of Chinese medicine preparation of the present invention.
The scorpion tail, the flat acrid in the mouth of property, return Liver Channel, endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Treatment of ulcer, scrofula, goiter, spasm tic etc.
Scolopendra, warm in nature, acrid in the mouth, have the function of endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain, controls scrofula, tuberculosis ， mass in the abdomen tumor piece, sore swollen toxin, pertussis, apoplexy, infantile convulsion etc.
Stir-baked SQUAMA MANITIS, salty being slightly cold, detumescence and apocenosis, eliminating stasis and resolving masses, Zhu Zhi lumps in the chest and abdomen, carbuncle kind sore.For amenorrhea due to stagnation of blood, lump in the abdomen caking, the diseases such as rheumatic arthralgia, the contracture of muscle arteries and veins.According to " Japan hanako materia medica ", put down in writing: " control ... anal fistula the malignant boil scabies." according to " the southern regions of the Yunnan Province book on Chinese herbal medicine ", put down in writing: " and control the carbuncle poison, the dispelling the stagnated QI promoting the circulation of blood, chest and diaphragm expands against gas.”
According to modern pharmacological research, above three make medicine that antitumaous effect in various degree all be arranged.The scorpion tail has direct cytotoxicity to cancerous cell, and Scolopendra obviously strengthens the reticuloendothelial system function, improves immunity of organisms, promotes lymphocyte transformation, strengthens the function anti-cancer ability.Stir-baked SQUAMA MANITIS also has certain anticancer therapeutic.
Above three flavor medical materials have the product of " flesh and blood is in love ", benefaction is walked to alter, search bone and pick wind, nowhere less than, as the pioneer of open circuit, the general who has no progeny, guide all medicines to go deep into the cancerous lung tissue deep layer, attack and kill carcinoma, the residual hazard of cleaning lung network blood vessels, assist monarch drug to play the dredging collateral mass dissipating and swelling eliminating that relieves the pain, the evacuation of pus counteracting toxic substances eliminating carbuncle effect of reducing phlegm.Simultaneously, the scorpion tail, Scolopendra is the prescription of proved recipe " Zhijing San ", can ingeniously dissolve the side effect of Semen Strychni, can make Chinese medicine preparation safety non-toxic of the present invention.
More than introduced of the present invention three and spent five sons six content and the pharmacology of each loose components in vain, based on above pharmacology, describe, " three spend five sons six in vain loose " of the present invention are can be effectively poly-for the patients with lung cancer stagnation of QI, expectorant knot, blood stasis, poison, simulataneous insufficiency and excessive, the evil Sheng pathogenic characteristic such as are just being damaged and implemented treatment, realize that Certain cancer, pendant cancer are relievingd asthma, eliminating toxic substances to remove stasis, eliminating stagnation analgesic therapy, lifting mechanism of qi, dredging lung network, hemostasis by removing blood stasis, by treatment mechanism such as expectorant diuretic, vital base and primordial QI consolidating, thereby reach desirable effect for cancer.
[embodiment]
Below introduce Chinese medicine three of the present invention and spend the white loose specific embodiment of five sons six.
The dosage of a course for the treatment of of take is example, adopts Saussurea involucrata Kar. et Kir. et Maxim. flower 25g, Flos Lonicerae 25g, Stigma Croci 25g, Galla Chinensis 20g, Semen Lepidii (Semen Descurainiae) 20g, Semen Strychni 20g, Fructus Schisandrae Chinensis 20g, Radix Semiaquilegiae 20g, Rhizoma Atractylodis Macrocephalae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Cortex Mori 15g, Herba Solani Lyrati 15g, Herba Hedyotidis Diffusae 15g, Alumen 15g, scorpion tail 10g, Scolopendra 10g, stir-baked SQUAMA MANITIS 10g.
Be more than the dosage of a course for the treatment of, the time of a common course for the treatment of is approximately about two weeks to month, take medicine every day 2 times, sooner or later use respectively mixing in water for oral taking 4～9g Chinese powder medicine, concrete dose is depending on patient's situation (such as body weight, disease serious degree, age etc.), and for example the each consumption of common adult is about 6g.Usually, the fastest medication treatment 1-3 can take effect a course for the treatment of, treats 10 and can cure more than the course for the treatment of.
Below introduce the preparation technology of the Chinese powder medicine of the embodiment of the present invention:
Saussurea involucrata Kar. et Kir. et Maxim. flower 25g, Flos Lonicerae 25g and Stigma Croci 25g are dried in the shade;
Semen Strychni 20g water is cooked off to skin, and section is dried, and uses the Oleum Sesami burned to yellow skin;
Galla Chinensis 20g, Semen Lepidii (Semen Descurainiae) 20g, Fructus Schisandrae Chinensis 20g, Radix Semiaquilegiae 20g, Rhizoma Atractylodis Macrocephalae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Cortex Mori 15g, Herba Solani Lyrati 15g, Herba Hedyotidis Diffusae 15g, scorpion tail 10g, Scolopendra 10g and stir-baked SQUAMA MANITIS 10g are dried;
The above-mentioned various medical materials that process are mixed with Alumen 15g;
The mixture of above-mentioned each medical material is pulverized repeatedly with pulverizer, until reach the above medicated powder of 40 orders, sealing saves backup.
In crushing process, can adopt special-purpose sieve will reach the above thin medicated powder of 40 orders and filter out, remaining coarse powder can be pulverized with pulverizer again, so repeatedly pulverizes repeatedly, repeats screening, until obtain satisfactory fine powder, avoids waste.
[clinical case]
Below introduce and adopt Chinese medicine three of the present invention to spend the white loose case of carrying out clinical treatment of five sons six.
Case 1
Female Lee 52 years old, have smoking history, and when health check-up, X finds left lung 2.8cm * 4.0cm agglomerate shadow, be diagnosed as left lung by provincial hospital CT examination and cytology's histological examination around property pulmonary carcinoma belong to middle differentiation adenocarcinoma, because being reluctant to perform the operation, examine out of admiration for a famous person.The patient there is no any discomfort.Each 9g morning and evening every day 2 mixing in water for oral taking of " three spend five sons six to fall apart in vain " of advising it to take the embodiment of the present invention.Further consultation after 2 months, the CT examination lump is contracted to 1.9cm * 2.3cm, and without any discomfort, rear clothes to 12 a month CT check pulmonary masses is eliminated.Consolidate again drug withdrawal after 6 months.Following up a case by regular visits to alive tumor after 2 years does not recur.
Case 2
Patient Tang, female 67 years old, start without obviously under inducement, cough and expectoration occurring in February, 2006, paroxysmal, the few color of expectorant is difficult for expectoration in vain, does not give attention.The hemoptysis of coughing after 2 months, be off one's feed, and fatiguability is weak, and body weight is the decline of carrying out property, approximately alleviates 5kg.Go provincial hospital medical, CT shows: the left hilus pulumonis visible one about 3.5cm of section * 2.5cm size soft tissue shadow, and form is irregular, Density inhomogeneity, and block lower-left lung main bronchus, after strengthening, the focus strengthening is obviously, have no obvious enlarged lymph node shadow in mediastinum, diagnostic imaging: the occupy-place of left hilus pulumonis section.And, in this institute's row fiberoptic bronchoscopy, pathological section shows: in, low differentiated squamous-cell carcinomas.Because of advanced in age, patient and family members refuse row operative treatment and chemicotherapy, examine out of admiration for a famous person.The patient clinical symptom is obvious, advises its " three spend five sons six to fall apart in vain " of taking the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.Further consultation after one month, patient's hemoptysis of coughing is eliminated substantially, suddenly feels weak.Continue to take " three spend five sons six to fall apart in vain " further consultation after 4 months, the CT of hospital checks left lung lump and is contracted to 2.2cm * 1.0cm.Remaining lung has no substantive focus, and in mediastinum, each structure is normal, has no the enlarged lymph node shadow.The patient is without bad symptom, body, and spirit, diet, sleep all normal.Advise it to continue to take " three spend five sons six to fall apart in vain " further consultation after 12 months, CT checks left lung lump and disappears, and all indexs are normal.Advise it to continue to strengthen treatment drug withdrawal in 6 months.Following up a case by regular visits to alive tumor after 2 years does not recur.
Case 3
Zhang 42 years old, have smoking history, the right side chest pain occurs, and companion's cough and asthma, become thin weak.Be diagnosed as the right lung peripheral to provincial hospital through CT and tissue pathology checking, differentiated squamous-cell carcinomas in genus, lump scope 5.2cm * 4.0cm, right breast is with a small amount of bloody pleural fluid.After examine out of admiration for a famous person, advise the each 9g of its " three spend five sons six in vain loose " that take the embodiment of the present invention every day of 2 mixing in water for oral taking sooner or later.Further consultation after 1 month, chest pain, the symptoms such as cough obviously alleviate., after 12 months, various symptoms are eliminated to advise it to continue clothes " three spend five sons six to fall apart in vain ".Through the X sheet, CT examination, hydrothorax and tumor disappear.Following up a case by regular visits to alive tumor after 2 years does not recur.
Case 4
The Wang, the man, 67 years old, the patient coughed uncomfortable in chest, 2 months out of breath.Look into and show at certain CT of hospital, left lung posterior lobe section shows a plurality of lesser tubercle, is fused into greater tubercle, the high density focus, and about 7cm, CT value 20HU, upper left lung tumor 7cm * 3.3cm is diagnosed as left lung occupying lesion, neoplasm in lung, bronchitis, emphysema.Examine out of admiration for a famous person.Disease: cough, out of breath, chest pain, spiritlessness and weakness, become thin obviously, indigestion and loss of appetite, advises its " three spend five sons six to fall apart in vain " of taking the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.Further consultation after taking medicine 1 month.Stable disease, the check lump has no increase, and cough is out of breath, chest pain, the symptom such as weak obviously alleviates, and advises it to continue to take.Treat further consultation after 12 months.Check shows: upper left lung lump, and neoplasm all disappears, and non-form size is all normal, does not find new focus.Advise it to consolidate and take medicine 6 months again.Follow up a case by regular visits to alive not recurrence after 2 years.
Case 5
Liu, the man, 45 years old, smoking history is arranged, obviously cough 3 months, while examining, the patient is with uncomfortable in chest, chest pain, and out of breath, the sputum mixed with blood silk, become thin, weak, heating, lip is purple dark, and right cervical lymph node enlargement is as egg, and breast CT checks near the lump 3.2cm * 3.5cm of right lung door.Advise its " three spend five sons six to fall apart in vain " of taking the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.After one week, body temperature is normal, uncomfortable in chest, and chest pain, alleviate; The sputum mixed with blood silk is controlled.After taking medicine 1 month, neck region lump is contracted to as the Fructus Jujubae size, the CT check, and right lung lump 2.2cm * 2.9cm, clinical symptoms is all eliminated.Continue to take " three spend five sons six in vain loose " to further consultation after 9 months, neck region lump, the right lung lump all disappears, and without uncomfortable, advises it to continue the after treatment of taking medicine.Take medicine after 12 months, the patient, spirit muscle power, it is normal that the diet sleep all recovers, without any discomfort.Consolidate again drug withdrawal after half a year.Follow up a case by regular visits to alive not recurrence after 3 years.
Case 6
Zhang, the right side chest pain, appear in female 42 years old, companion's cough, asthma, become thin, weak, the chest x-ray film making, CT and histopathological examination are diagnosed as in the right lung peripheral and break up adenocarcinoma, lump scope 5.2cm * 4.1cm, and right lung is with middle amount bloody pleural fluid, advise its " three spend five sons six to fall apart in vain " of taking the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.Further consultation after 1 month, chest pain, the clinical symptoms such as cough obviously alleviate, and spirit takes a turn for the better, and appetite is prosperous.After taking medicine 10 months, various symptoms are eliminated, and through CT examination, hydrothorax and tumor disappear, and advise its after treatment drug withdrawal in 6 months again.After 2 years, follow up a case by regular visits to, alive, without any Tumor-assaciated symptom.
Case 7
Zhao, female, 52 years old, the right side chest pain occurs, cough uncomfortable in chest, become thin weak, low grade fever, right cervical region monoblock is as large as Fructus Jujubae, through X, makes film, CT and histopathological examination, be diagnosed as the right lung peripheral type carcinoma of lung, differentiated squamous-cell carcinomas in genus, the right breast of lump scope 4.2cm * 3.5cm is with a small amount of bloody pleural fluid, advise its " three spend five sons six to fall apart in vain " of taking the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.After 1 month, further consultation is uncomfortable in chest, and the clinical symptoms such as cough obviously alleviate, and low grade fever is eliminated, and suddenly feels weak, and neck region lump is contracted to the soybean grain size, advises it to continue to take medicine.Further consultation after 10 months, all clinical symptoms and neck region lump disappear, and CT examination hydrothorax and tumor disappear, and advise its after treatment drug withdrawal in 6 months again, after 5 years, follow up a case by regular visits to alive.And the Tumor-assaciated symptom does not appear.
Case 8
Qi, female 65 years old, patient's cough, asthma, left side chest pain 3 months, through certain CT of hospital and histopathological examination, be diagnosed as left lung property pulmonary carcinoma on every side, break up adenocarcinoma in genus, the left breast of lump scope 3.6cm * 3.5cm is with a small amount of hydrothorax, because being reluctant to perform an operation and chemicotherapy is examined.Advise its " three spend five sons six to fall apart in vain " of taking the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.Further consultation after 1 month, the cough chest pain obviously alleviates, and spirit takes a turn for the better, and muscle power strengthens, and body weight increases, and the CT examination lump is contracted to 2.4cm * 2.3cm, and hydrothorax disappears.Advise it to continue to take medicine.Further consultation after 6 months, the Tumor-assaciated symptom is slight, spirit, diet, sleep all good, the chest x-ray film making, lump is contracted to 1.5cm * 1.0cm, rear because of the drug withdrawal voluntarily of family's reason, advises its emotion that keeps pleasant.
Case 9
Lee, female 57 years old, have smoking history, and cough increases the weight of 3 months, does not give attention, the asthma of right side chest pain occurs afterwards, coughs frothy sputum, accompanies weakly, becomes thin, and anorexia is medical.Be diagnosed as the right lung central type carcinoma of lung through chest X film making CT and histopathology cytolgical examination, break up adenocarcinoma in genus.Near the lump 2.9cm * 2.4cm right lung door, advise its " three spend five sons six to fall apart in vain " of taking the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.Further consultation after 2 months, various clinical symptom disappearance, spirit takes a turn for the better, and appetite increases, and muscle power strengthens, and body weight increases, the chest x-ray film making, lump is contracted to 1.2cm * .0.8cm.After adhere to taking medicine after 12 months, further consultation, without any discomfort symptom, breast CT check lump disappears.After advise its after treatment drug withdrawal after 6 months again, take good care of voluntarily.Follow up a case by regular visits to and be still living and in good health in 5 years, without the Tumor-assaciated symptom.
Visible by above clinical case, Chinese medicine preparation three of the present invention spends five sons six to be dispersed in vain treatment pulmonary carcinoma or the lung tumors aspect has obvious clinical efficacy, therapeutic effect is obvious, have no side effect, therapeutic process is simple and safe, adheres to oral getting final product, and need not carry out traditional radiation and chemotherapy formality, reduce patient's misery and medical expense, greatly extended patient's life-span.
Chinese medicine three of the present invention is spent the white loose following significant advantage that has of five sons six:
(1) take the lead in " Tibetan medicine " as " monarch drug " for cancer and the dialectical compatibility of Chinese medicine.With medicine in the past, compare, formula is novel, and drug effect is remarkable, and safety non-toxic more verifiedly can reach obvious good efficacy.
(2) take the lead in " getting analogy as method " and " physicopsychic training techniques " principle apply to the treatment cancer Chinese medicine in, the highest dialectical aim that treats that meets Huangdi's Internal Classics " behaving according to the law of YIN YANG; close in physicopsychic training techniques ", it is the innovation of Chinese medical discrimination philosophizing mode, thereby make Chinese medicine preparation of the present invention for cancer more accurate, onset is rapider, cures more thorough.
Specifically, the lung five elements belong to gold, are three yin meridians of foot, main gas, and its matter is light clearly, and its color is white, as fornix, is the canopy of the five internal organs, and Xuan Fasu falls, and with the kidney mutual generation between metal and water, breathes expiration and inspiration, completes the ascending, descending, exiting and entering of mechanism of qi.
The monarch drug of compatibility in Chinese medicine of the present invention " three flowers " has light clearly matter, and light weight raises up, and with lung, with gas phase, throws, and directly enters fornix.It spends three flavors to answer number that Eight Diagrams are congenital from hexagram, and its position is upper, color be red should sick position at the blood system of lung.Impel monarch drug to go deep into lungs, through cancerous tissue.The ministerial drug of compatibility " five sons " is got its matter and is heavily dropped, the therapeutic method to keep the adverse QI flowing downwards of astringing the lung, and improving inspiration by invigorating kidney-QI is returned kidney, and mothers and sons are joined, the lifting mechanism of qi.Its number gets five, answers the number xun, one of the Eight Diagrams hexagram that Eight Diagrams are congenital, and xun, one of the Eight Diagrams is wind, and wind is that gas is moving, answers ascending or descending movement of vital Qi to come in and go out and moves, and impels QI movement being in harmonious way, falls the cancer poison of falling.The adjuvant drug of compatibility " six is white " Bai Yiying lung, be beneficial in the up lung of medicine gesture.Its number gets six, answers the number bank six that Eight Diagrams are congenital, to answer kidney water, mutual generation between metal and water.Merit is first in solid lung training, is beneficial to again lung qi lifting expiration and inspiration.
(3) take the lead in adopting " two principles " prescription, compare Chinese medicine, the lung cancer therapy effect is more definite.Specifically, Chinese medicine preparation of the present invention forms and not only meets the traditional Chinese medical science " principle-method-recipe-medicines ", the principles of formulating prescriptions of " dialectical execute it ", and confirm clearly there is the anticancer cancer composition that kills through " modern pharmacological research ".It is to have the anticancer Chinese medicine that kills the cancer composition through modern pharmacology checking that 16 flavor Chinese medicines are arranged in Chinese medicine preparation of the present invention, has verifiedly greatly shortened the course for the treatment of for cancer.
(4) Chinese medicine preparation of the present invention is oral type powder, the meaning of " loose evil " is arranged, there is drug effect and bring into play characteristics rapidly, especially avoided indivedual effective ingredient due to decoction decocting to lose efficacy, also avoid the modern Chinese medicine purification technique to destroy the inherent rock-steady structure of Chinese medicine, caused the unbalance drawback of ingredient.The functional principle that simultaneously meets Chinese medicine " letter, test, just, honest and clean ".
Should be understood that, the above-mentioned specific embodiment of the present invention is only for exemplary illustration or explain principle of the present invention, and is not construed as limiting the invention.Therefore, in the situation that any modification of making without departing from the spirit and scope of the present invention, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.In addition, claims of the present invention are intended to contain whole variations and the modification in the equivalents that falls into claims scope and border or this scope and border.
Claims (4)
1. a Chinese medicine three for the treatment of pulmonary carcinoma spends five sons six loose in vain, and it comprises the component of following mass fraction:
Saussurea involucrata Kar. et Kir. et Maxim. is spent 25 parts, 25 parts of Flos Loniceraes, 25 parts of Stigma Crocis, 20 parts of Galla Chinensiss, 20 parts of Semen Lepidii (Semen Descurainiae)s, 20 parts of Semen Strychni, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Radix Semiaquilegiaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Cortex Mori, 15 parts of Herba Solani Lyratis, 15 parts of Herba Hedyotidis Diffusaes, 15 parts of Alumens, 10 parts, scorpion tail, 10 parts of Scolopendras, 10 parts of stir-baked SQUAMA MANITISs.
2. according to claim 1 three spend five sons six loose in vain, the component dosage of one course for the treatment of is:
Saussurea involucrata Kar. et Kir. et Maxim. flower 25g, Flos Lonicerae 25g, Stigma Croci 25g, Galla Chinensis 20g, Semen Lepidii (Semen Descurainiae) 20g, Semen Strychni 20g, Fructus Schisandrae Chinensis 20g, Radix Semiaquilegiae 20g, Rhizoma Atractylodis Macrocephalae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Cortex Mori 15g, Herba Solani Lyrati 15g, Herba Hedyotidis Diffusae 15g, Alumen 15g, scorpion tail 10g, Scolopendra 10g, stir-baked SQUAMA MANITIS 10g.
3. a Chinese medicine three for the treatment of pulmonary carcinoma is spent five son six white loose preparation technologies, comprises the steps:
Spend 25 parts of 25 parts, 25 parts of Flos Loniceraes and Stigma Crocis to dry in the shade Saussurea involucrata Kar. et Kir. et Maxim.;
20 portions of waters of Semen Strychni are cooked off to skin, and section is dried, and uses the Oleum Sesami burned to yellow skin;
By 20 parts of Galla Chinensiss, 20 parts of Semen Lepidii (Semen Descurainiae)s, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Radix Semiaquilegiaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Cortex Mori, 15 parts of Herba Solani Lyratis, 15 parts of Herba Hedyotidis Diffusaes, 10 parts, scorpion tail, 10 parts of Scolopendras and 10 parts of oven dry of stir-baked SQUAMA MANITIS;
Above-mentioned each medical material processed is mixed with 15 parts of Alumens;
The mixture of above-mentioned each medical material is pulverized repeatedly with pulverizer, until reach the above medicated powder of 40 orders.
4. in claim 1-2, the described Chinese medicine three of any one spends five sons six to be dispersed in vain for the preparation of the application in the product for the treatment of pulmonary carcinoma.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103920008A (en) * | 2014-04-28 | 2014-07-16 | 张增贵 | Chinese medicinal composition for treating cancers |
| CN106177300A (en) * | 2016-08-31 | 2016-12-07 | 殷晓燕 | A kind of medicine pill for pulmonary carcinoma auxiliary treatment and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1422640A (en) * | 2001-12-05 | 2003-06-11 | 李佩文 | Medicine for treating lung cancer and its preparation method |
| CN101049484A (en) * | 2007-05-14 | 2007-10-10 | 郝来勤 | Strong effective Chinese traditional medicine for treating lung cancer and other various cancers |
| CN102397490A (en) * | 2010-09-10 | 2012-04-04 | 高菲 | Preparation method of traditional Chinese medicinal prescription for treating lung cancer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1422640A (en) * | 2001-12-05 | 2003-06-11 | 李佩文 | Medicine for treating lung cancer and its preparation method |
| CN101049484A (en) * | 2007-05-14 | 2007-10-10 | 郝来勤 | Strong effective Chinese traditional medicine for treating lung cancer and other various cancers |
| CN102397490A (en) * | 2010-09-10 | 2012-04-04 | 高菲 | Preparation method of traditional Chinese medicinal prescription for treating lung cancer |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103920008A (en) * | 2014-04-28 | 2014-07-16 | 张增贵 | Chinese medicinal composition for treating cancers |
| CN106177300A (en) * | 2016-08-31 | 2016-12-07 | 殷晓燕 | A kind of medicine pill for pulmonary carcinoma auxiliary treatment and preparation method thereof |
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