CN103432401B - Traditional Chinese medicine powder prepared from three flowers, five seeds and six whites for treating lung cancer - Google Patents
Traditional Chinese medicine powder prepared from three flowers, five seeds and six whites for treating lung cancer Download PDFInfo
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Abstract
Traditional Chinese medicine powder prepared from three flowers, five seeds and six whites for treating lung cancer comprises the following components by weight: 25 parts of tibetan snow lotus, 25 parts of honeysuckle, 25 parts of saffron, 20 parts of gallnut, 20 parts of semen lepidii, 20 parts of poison nut, 20 parts of shizandra berry, 20 parts of radix semiaquilegiae, 15 parts of atractylis ovata, 15 parts of bletilla striata, 15 parts of white mulberry root-bark, 15 parts of bittersweet herb, 15 parts of spreading hedyotis herb, 15 parts of alum, 10 parts of scorpion tails, 10 parts of centipede and 10 parts of stir-baked squama manitis. The Traditional Chinese medicine powder prepared from the three flowers, the five seeds and the six whites provided by the invention has an obvious clinical curative effect on treating lung cancer or lung tumor, is obvious in curative effect, has no toxic or side effect, is simple and safe in therapeutic process, reduces pain of a patient, lowers the treatment cost, and greatly prolongs the patient life.
Description
Technical field
The present invention relates to Chinese medicine compound and application thereof, especially, relate to a kind of Chinese medicine three being used for the treatment of pulmonary carcinoma and spend five sons six to fall apart in vain, and the application in treatment pulmonary carcinoma.
Background technology
Malignant tumor becomes the No.1 Health Killer of the 21 century mankind, WTO expect the year two thousand thirty the whole world 1,700 ten thousand people will be had to die from cancer every year.And the whole world is diagnosed as cancer per year over 1200 ten thousand people.Inland of China is newly-increased number of cancer deaths 1,500,000 every year, accounts for 20% of the whole world.And pulmonary carcinoma occupies global cancer first place always, the treatment of pulmonary carcinoma is the emphasis that global medical circle is paid close attention to always.The advantage of Chinese Traditional Medicine in cancer treatment procedure gradually admit by medical circle, become the radiotherapy that continues, chemotherapy, the fourth-largest anticancer means beyond operation, and the status in anticancer therapy is got over important.
Pulmonary carcinoma belongs to the traditional Chinese medical science " lung cellulitis ", " pulmonary distension ", " lump in the right hypochondrium ", " lump at the right hypochondrium " category, and because human righteousness is weak, imbalance of YIN and YANG, evil poison is taken advantage of a weak point in opponent's defence and invaded, and causes visceral dysfunction, and the stagnation of QI, expectorant knot, blood stasis, poison is poly-, with the passing of time forms lump.For patients with lung cancer, gas, expectorant, the stasis of blood, poison are pathological product, are also paathogenic factors, simultaneously simulataneous insufficiency and excessive, so that evil Sheng is just damaged.
For the Chinese pathology feature of pulmonary carcinoma, need to develop a kind of Chinese medicine can treating pulmonary carcinoma, it can produce good curative effect for the etiology and pathogenesis feature of pulmonary carcinoma.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine three for the treatment of pulmonary carcinoma spends five sons six to fall apart in vain, in treatment pulmonary carcinoma and lung tumors, have good curative effect, no side effects.
According to an aspect of the present invention, providing a kind of Chinese medicine three for the treatment of pulmonary carcinoma spends five sons six to fall apart in vain, and it comprises the component of following mass fraction: Saussurea involucrata Kar. et Kir. et Maxim. spend 25 parts, Flos Lonicerae 25 parts, Stigma Croci 25 parts, Galla Chinensis 20 parts, Semen Lepidii (Semen Descurainiae) 20 parts, Semen Strychni 20 parts, Fructus Schisandrae Chinensis 20 parts, Radix Semiaquilegiae 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, Cortex Mori 15 parts, Herba Solani Lyrati 15 parts, Herba Hedyotidis Diffusae 15 parts, Alumen 15 parts, 10 parts, scorpion tail, Scolopendra 10 parts, stir-baked SQUAMA MANITIS 10 parts.
Preferably, the component dosage that the present invention three spends five sons six to fall apart a course for the treatment of is in vain: Saussurea involucrata Kar. et Kir. et Maxim. flower 25g, Flos Lonicerae 25g, Stigma Croci 25g, Galla Chinensis 20g, Semen Lepidii (Semen Descurainiae) 20g, Semen Strychni 20g, Fructus Schisandrae Chinensis 20g, Radix Semiaquilegiae 20g, Rhizoma Atractylodis Macrocephalae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Cortex Mori 15g, Herba Solani Lyrati 15g, Herba Hedyotidis Diffusae 15g, Alumen 15g, scorpion tail 10g, Scolopendra 10g, stir-baked SQUAMA MANITIS 10g.
According to a further aspect in the invention, provide a kind of Chinese medicine three for the treatment of pulmonary carcinoma and spend the preparation technologies that five sons six are in vain loose, comprise the steps: Saussurea involucrata Kar. et Kir. et Maxim. to spend 25 parts, Flos Lonicerae 25 parts and Stigma Croci 25 parts dry in the shade; By Semen Strychni 20 parts decocting in water peeling, section is dried, with Oleum Sesami burned to yellow skin; By Galla Chinensis 20 parts, Semen Lepidii (Semen Descurainiae) 20 parts, Fructus Schisandrae Chinensis 20 parts, Radix Semiaquilegiae 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, Cortex Mori 15 parts, Herba Solani Lyrati 15 parts, Herba Hedyotidis Diffusae 15 parts, 10 parts, scorpion tail, Scolopendra 10 parts and stir-baked SQUAMA MANITIS 10 parts oven dry; The above-mentioned each medical material processed is mixed with Alumen 15 parts; The mixture pulverizer of above-mentioned each medical material is pulverized repeatedly, until reach the medicated powder of more than 40 orders.
According to a further aspect in the invention, relating to aforementioned Chinese medicine three spends five sons six to be dispersed in vain for the preparation of the application in the product for the treatment of pulmonary carcinoma.
Chinese medicine preparation three of the present invention spends five sons six to be dispersed in treatment pulmonary carcinoma in vain or lung tumors aspect has obvious clinical efficacy, therapeutic effect is obvious, have no side effect, therapeutic process is simple and safe, adhere to oral, traditional radiation and chemotherapy formality need not be carried out, decrease misery and the medical expense of patient, substantially prolongs the life-span of patient.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearly understand, below in conjunction with detailed description of the invention, the present invention is described in more detail.Should be appreciated that, these describe just exemplary, and do not really want to limit the scope of the invention.In addition, in the following description, the description to known technology is eliminated, to avoid unnecessarily obscuring concept of the present invention.
The Chinese medicine being used for the treatment of pulmonary carcinoma that the present invention proposes is by name " three spend five sons six to fall apart in vain ", and it comprises the component of following mass fraction: Saussurea involucrata Kar. et Kir. et Maxim. spend 25 parts, Flos Lonicerae 25 parts, Stigma Croci 25 parts, Galla Chinensis 20 parts, Semen Lepidii (Semen Descurainiae) 20 parts, Semen Strychni 20 parts, Fructus Schisandrae Chinensis 20 parts, Radix Semiaquilegiae 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, Cortex Mori 15 parts, Herba Solani Lyrati 15 parts, Herba Hedyotidis Diffusae 15 parts, Alumen 15 parts, 10 parts, scorpion tail, Scolopendra 10 parts, stir-baked SQUAMA MANITIS 10 parts.
Traditional Chinese medical science pharmacology analysis is carried out to above-mentioned each component below.
Saussurea involucrata Kar. et Kir. et Maxim. flower, warm in nature, sweet in the mouth, hardship, enter spleen, kidney channel, has cold relieving tonifying YANG, the merit of removing toxic substances and promoting subsidence of swelling, regulating menstruation, hemostasis, is applicable to positive QI-insufficiency, asthenia is thin and weak, carcinoma is sluggish, the diseases such as traumatic hemorrhage.The congenital the foundation of acquired constitution of flat benefit.
Flos Lonicerae, sweet in the mouth cold in nature, fragrant odour, returns lung, stomach, heart channel.Merit at heat-clearing and toxic substances removing, wind-heat dissipating, treatment of ulcer toxic swelling, carbuncle furuncle.Compendium of Material Medica is carried " Flos Lonicerae, is good at removing toxic substances, therefore controls carbuncle, toxic swelling, skin ulcer tinea ... ", and " medical center is usurped and wanted-the property of medicine " is referred to as " persons particularly liable to develop skin infection's principal agent ".
Stigma Croci, cool in nature, sweet in the mouth, micro-hardship, there is the merit of the silt of thin channels and activating collaterals, stimulating the menstrual flow, scattered silt relieving accumulation of pathogens, reducing swelling and alleviating pain, removing pathogenic heat from blood and toxic substance from the body.Cure mainly, chest and diaphragm painful abdominal mass is vexed, and ecchymosis swells and ache, and spits blood, goes mad, frightened fear in a trance disease.
According to modern pharmacological research, above-mentioned three medical materials all have the powerful active component killing cancerous cell.Wherein crocetin, crocin and Picrocrocin have stronger active anticancer.Its anticancer mechanism is DNA and the RNA synthesis of anticancer, the activity of T suppression cell protein kinase and the expression of proto-oncogene; Xuelianhuangtong compounds, and Herba Saussureae Involueratae alkaloid has the inhibitory action shown to DNA, RNA of cancerous cell and protein synthesis.Flos Lonicerae while anticancer, can strengthen immune function of human body, promotes lymphocyte transformation, strengthens leukocytic phagocytic function.
Above three taste medicines also claim " three flowers ", get the meaning of its " all flowers all rise ", light weight raises up, the canopy of through the five internal organs, attack cancer poison and just do not hinder, detoxification and removing stasis and do not stay heresy, plays eliminating toxic substances to remove stasis, mass dissipating and swelling eliminating jointly, dredging lung network, hemostasis by removing blood stasis, the effect of Certain cancer, can as the monarch drug of Chinese medicine preparation of the present invention.
Galla Chinensis is sour, salty, flat.Return liver,spleen,kidney, lung, large intestine channel.There is anticancer, convergence lung qi, hemostasia and detumescence the merit that relieves internal heat.Cure mainly chronic cough of deficiency lung, night sweat, the diseases such as toxic swelling.Record according to Compendium of Material Medica " pathogenic fire reducing of astringing the lung, reduce phlegm drink, and cough-relieving is coughed, detumescence poison, hold back routed skin ulcer ... " effect.
Semen Strychni, bitter in the mouth is cold in nature, returns liver, spleen channel, has mass dissipating and swelling eliminating, removing obstruction in the collateral to relieve pain, and anticancer merit of relievining asthma, cures mainly ulcer sore pain, and insensitive impediment is numb, and chronic cough is panted.Have according to Compendium of Material Medica that " disappear mass in the abdomen." merit; Recording according to " surgery is raw collection entirely " can " the expectorant poison that in peeling, film condenses outward.”
Semen Lepidii (Semen Descurainiae), bitter in the mouth, pungent, in Great Cold, return lung, urinary bladder channel, eliminating pathogen from the lung for relieving asthma, line water detumescence, cure mainly sputum and stop up lung, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, the diseases such as sleeping, ascites pleural fluid swollen, dysuria must not be put down.“ Zhu lumps in the chest and abdomen stagnation of QI is recorded, diet cold and heat according to Shennong's Herbal, broken hard by heresy, tonneau water channel.”
Fructus Schisandrae Chinensis, sour, sweet, warm, there is supplementing QI for promoting the production of body fluid, a nourishing kidney of astringing the lung, the merit of arresting seminal emission of calming the nerves, cure mainly chronic cough dyspnea due to deficiency, the few disease such as xerostomia, forgetful insomnia in Tianjin.Record according to Shennong's Herbal: " main QI invigorating, cough with dyspnea, the thin degree of impairment caused by overstrain, tonifying for the deficiency, reinforcing YIN-essence.”
Radix Semiaquilegiae, cold in nature, sweet in the mouth is pungent, micro-hardship, return liver, spleen, urinary bladder channel, have heat-clearing and toxic substances removing, relieving asthma, calm the frightened, dispersing swelling and dissipating binds, the merit of relieving stranguria by diuresis, cures mainly carbuncle, scrofula, cough due to deficiency of the lung, records according to another " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " loose all skin ulcers swell; attack carbuncle, evacuation of pus analgesic therapy, controls scrofula; dissipation tuberculosis ... breast carcinoma as hard as flint, clothes loose or routed ".
According to modern pharmacological research, above gomi herbs all has the direct or indirect effect of killing cancerous cell.Gallotannin can solidify and the former tannin of destruction of cancer cells, and have antitumor action, such as, to murine sarcoma S-180, the suppression ratio of human cervix cancer cells JTC-26 all reaches more than 90%.Semen Strychni has extensive antitumaous effect, as all having antitumaous effect to sarcoma S-180 and leukaemia.Semiadoxoin A has stronger cytotoxic effect, effective to kinds cancer.It is worth mentioning that, Fructus Schisandrae Chinensis effective ingredient, the accumulation of antineoplastic agent in cells of resistant tumors can be increased, greatly improve the sensitivity to anti-tumor medicine.Potentiation is played to whole prescription.
Above five kinds of Chinese medicine also claims " five sons ", and get the meaning of its " "the philosophers," referring to the philosophers or their works, outside the Confucianists all falls ", matter heavily drops, the therapeutic method to keep the adverse QI flowing downwards of astringing the lung, and improving inspiration by invigorating kidney-QI returns unit, and mothers and sons connect, orderly and clearly mechanism of qi.Jointly play pendant cancer to relieving asthma, by expectorant diuretic, hardship is let out acid and is held back, the effect of harmonizing the functional activities of vital QI, can as the ministerial drug of Chinese medicine preparation of the present invention.
The Rhizoma Atractylodis Macrocephalae, warm in nature, bitter in the mouth, sweet, return spleen, stomach warp.Air making-up and spleen enlivening, dampness diuretic, anticancer.Cure mainly insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, the diseases such as the prolonged illness deficiency of vital energy.
The Pseudobulbus Bletillae (Rhizoma Bletillae), bitter, sweet, puckery, be slightly cold.Return lung, liver, stomach warp.Merit is in tonifying the lung, and hemostasis, detumescence, granulation promoting, sore, cures mainly, and lung hinders hemoptysis, epistaxis, and incised wound is hemorrhage, swollen ulcer drug, canker sores.Record according to " the southern regions of the Yunnan Province book on Chinese herbal medicine ": the merit of " control consumptive disease impairing the lung gas, tonifying the lung is empty, and cough-relieving is coughed, the pulmonary tuberculosis that disappears hemoptysis, convergence lung ".And " herbal classic " has: " main carbuncle malignant boil loses cellulitis, the dead flesh of impairment of YIN.”
Cortex Mori, sweet; Pungent; Cold in nature, return lung; Spleen channel.Eliminating pathogen from the lung for relieving asthma; Inducing diuresis to remove edema, cures mainly lung-heat and breathes heavily expectorant; Diseases caused by retention of fluid stops lung; Distension dyspnea with rapid respiration, have " sweet with the deficiency of reinforcing premodial qi tonify deficiency, pungent having a surplus and antitussive with eliminating the pathogens from the lung gas." good reputation.
Herba Solani Lyrati, bitter, flat, clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, anticancer.
Herba Hedyotidis Diffusae, bitter, sweet, cold.Return stomach, large intestine, small intestine meridian.Heat-clearing and toxic substances removing, dampness removing is treating stranguria, anticancer.Cure mainly carbuncle sore tumefacting virus, cancerous protuberance pain.
Alumen, cold in nature, sour-puckery flavor, returns lung, liver, spleen, large intestine channel, anticancer, the dampness detumescence of relieving internal heat, astringing to arrest bleeding, expectorant of dispeling the wind.Record according to Compendium of Material Medica: " dampness is detoxified, and chases after saliva, hemostasis analgesic therapy, and meat is disliked in erosion, and raw good meat is controlled carbuncle furuncle and swollen, swollen ulcer drug malignant boil, the merit of brave dog snakes and scorpions hundred insect bite.”
According to modern pharmacological research, above Six-element medical material majority has the effect of killing cancerous cell.The Rhizoma Atractylodis Macrocephalae has cytotoxicity to oncocyte, can reduce the rate of increase of oncocyte, lowers the aggressive of tumor tissue, improves the ability of body antitumor reaction; The Pseudobulbus Bletillae (Rhizoma Bletillae) contains phlegmatic temperament polysaccharide, has antitumaous effect; Herba Solani Lyrati anticancer effective component is B-solamarine, is broad-spectrum anticarcinogen; Contained by Herba Hedyotidis Diffusae, number of chemical composition has inhibitory action to all kinds of cancer, and its extract energy activated T lymphocytes, makes it discharge interferon, kill tumor cell, has the effect strengthening human body non-specific immunity; Alumen can impel cancer surrounding tissue fibrosis, vessel wall thickening, neointimal hyperplasia, thrombosis, and a large amount of neutrophilic granulocytes, mononuclear cell, phagocyte and lymphocyte aggregation can be produced, make cancerous tissue downright bad, thus play the growth of anticancer and the effect of transfer, active anticancer can reach 70% ~ 90%.
Above Six-element medicine also claims " six is white ", gets the meaning of its " Bai Yiying lung ", and assistant principal drug assistance ministerial drug, plays building up the spleen to supplement the lung, invigorating the spleen to benefit the lung, granulation promoting primordial QI reinforcing, the merit of anticancer analgesic therapy of reducing phlegm, can as the adjuvant drug of Chinese medicine preparation of the present invention.
Scorpion tail, the flat acrid in the mouth of property, returns Liver Channel, endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Treatment of ulcer, scrofula, goiter, spasm tic etc.
Scolopendra, warm in nature, acrid in the mouth, has the function of endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain, controls, scrofula, tuberculosis ， mass in the abdomen tumor block, sore swollen toxin, pertussis, apoplexy, infantile convulsion etc.
Stir-baked SQUAMA MANITIS, is saltyly slightly cold, detumescence and apocenosis, eliminating stasis and resolving masses, Zhu Zhi lumps in the chest and abdomen, carbuncle kind sore.For amenorrhea due to stagnation of blood, lump in the abdomen lumps, the diseases such as rheumatic arthralgia, the contracture of muscle arteries and veins.Record according to " Japan hanako materia medica ": " control ... anal fistula, malignant boil scabies." record according to " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " control carbuncle poison, dispelling the stagnated QI promoting the circulation of blood, chest and diaphragm expands against gas.”
According to modern pharmacological research, above three make medicine all have antitumaous effect in various degree.Scorpion tail has direct cytotoxicity to cancerous cell, and Scolopendra obviously strengthens reticuloendothelial system function, improves immunity of organisms, promotes lymphocyte transformation, strengthens function anti-cancer ability.Stir-baked SQUAMA MANITIS also has certain anticancer therapeutic.
Above three taste medical materials have the product of " flesh and blood is in love ", benefaction is walked to alter, search bone and pick wind, nowhere less than, as the pioneer of open circuit, the general had no progeny, guide all medicines to go deep into cancerous lung tissue deep layer, attack and kill carcinoma, the residual hazard of cleaning lung network blood vessels, assist monarch drug to play dredging collateral to relieve the pain mass dissipating and swelling eliminating, evacuation of pus counteracting toxic substances eliminating carbuncle effect of reducing phlegm.Meanwhile, scorpion tail, Scolopendra is the prescription of proved recipe " Zhijing San ", ingeniously can dissolve the side effect of Semen Strychni, can make Chinese medicine preparation safety non-toxic of the present invention.
Be described above content and pharmacology that of the present invention three spend each component that five sons six are loose in vain, describe based on above pharmacology, " three spend five sons six to fall apart in vain " of the present invention effectively poly-for the patients with lung cancer stagnation of QI, expectorant knot, blood stasis, poison, simulataneous insufficiency and excessive, evil Sheng the pathogenic characteristic such as just can to damage and is implementing treatment, realize Certain cancer, pendant cancer is relievingd asthma, eliminating toxic substances to remove stasis, eliminating stagnation analgesic therapy, lifting mechanism of qi, dredging lung network, hemostasis by removing blood stasis, by cure mechanism such as expectorant diuretic, vital base and primordial QI consolidating, thus reach desirable effect for cancer.
[embodiment]
Introduce Chinese medicine three of the present invention below and spend the specific embodiment that five sons six are loose in vain.
For the dosage of a course for the treatment of, adopt Saussurea involucrata Kar. et Kir. et Maxim. flower 25g, Flos Lonicerae 25g, Stigma Croci 25g, Galla Chinensis 20g, Semen Lepidii (Semen Descurainiae) 20g, Semen Strychni 20g, Fructus Schisandrae Chinensis 20g, Radix Semiaquilegiae 20g, Rhizoma Atractylodis Macrocephalae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Cortex Mori 15g, Herba Solani Lyrati 15g, Herba Hedyotidis Diffusae 15g, Alumen 15g, scorpion tail 10g, Scolopendra 10g, stir-baked SQUAMA MANITIS 10g.
Be more than the dosage of a course for the treatment of, the time of a usual course for the treatment of is approximately two weeks by about one month, take medicine every day 2 times, sooner or later mixing in water for oral taking 4 ~ 9g Chinese powder medicine is used respectively, concrete dose is depending on patient profiles's (such as body weight, disorder severity, age etc.), and each consumption of such as average adult is about 6g.Usually, the fastest medication treatment 1-3 can take effect a course for the treatment of, and treating more than 10 courses for the treatment of can cure.
Introduce the preparation technology of the Chinese powder medicine of the embodiment of the present invention below:
Saussurea involucrata Kar. et Kir. et Maxim. flower 25g, Flos Lonicerae 25g and Stigma Croci 25g are dried in the shade;
Removed the peel by Semen Strychni 20g decocting in water, section is dried, with Oleum Sesami burned to yellow skin;
Galla Chinensis 20g, Semen Lepidii (Semen Descurainiae) 20g, Fructus Schisandrae Chinensis 20g, Radix Semiaquilegiae 20g, Rhizoma Atractylodis Macrocephalae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Cortex Mori 15g, Herba Solani Lyrati 15g, Herba Hedyotidis Diffusae 15g, scorpion tail 10g, Scolopendra 10g and stir-baked SQUAMA MANITIS 10g are dried;
The above-mentioned various medical material processed is mixed with Alumen 15g;
Repeatedly pulverized by the mixture pulverizer of above-mentioned each medical material, until reach the medicated powder of more than 40 orders, sealing saves backup.
In crushing process, special sieve can be adopted to be filtered out by the thin medicated powder reaching more than 40 orders, remaining coarse powder can be pulverized with pulverizer again, so repeatedly pulverizes repeatedly, repeats screening, until obtain satisfactory fine powder, avoids waste.
[clinical case]
Introduce below and adopt Chinese medicine three of the present invention to spend five sons six loose case of carrying out clinical treatment in vain.
Case 1
Female Lee 52 years old, has smoking history, and when health check-up, X finds left lung 2.8cm × 4.0cm agglomerate shadow, is diagnosed as the peripheral pulmonary carcinoma of left lung belongs to middle differentiation adenocarcinoma by provincial hospital CT examination and cytology's histological examination, because being reluctant that operation is examined out of admiration for a famous person.Patient there is no any discomfort.Advise its " three spend five sons six to fall apart in vain " the taking the embodiment of the present invention each 9g every day of 2 mixing in water for oral taking sooner or later.Further consultation after 2 months, CT examination mass reduction is to 1.9cm × 2.3cm, and without any discomfort, rear clothes to a 12 month CT checks pulmonary masses and eliminates.Consolidate again drug withdrawal after 6 months.Follow up a case by regular visits to alive tumor after 2 years not recur.
Case 2
Patient Tang, female 67 years old, starts to occur cough and expectoration, paroxysmal without under obvious inducement in February, 2006, and the white not easily expectoration of the few color of expectorant, does not give attention.Cough after 2 months hemoptysis, be off one's feed, fatiguability is weak, and body weight is that Progressive symmetric erythrokeratodermia declines, and about alleviates 5kg.Go provincial hospital to go to a doctor, CT shows: left hilus pulumonis portion visible about 3.5cm × 2.5cm size soft tissue shadow, and form is irregular, Density inhomogeneity, and block lower-left lung main bronchus, after strengthening, focus strengthening is obviously, obvious enlarged lymph node shadow is had no, diagnostic imaging: left hilus pulumonis portion occupy-place in mediastinum.And in this institute's row fiberoptic bronchoscopy, pathological section shows: in, low differentiated squamous-cell carcinomas.Because of advanced in age, patient and family members refuse row operative treatment and chemicotherapy, examine out of admiration for a famous person.Patient clinical symptom is obvious, advises it to take " three spend five sons six to fall apart in vain " of the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.Further consultation after one month, patient's hemoptysis of coughing is eliminated substantially, suddenly feels weak.Continue to take " three spend five sons six to fall apart in vain " further consultation after 4 months, hospital CT checks left lung neoplasms and is contracted to 2.2cm × 1.0cm.Remaining lung has no substantive focus, and in mediastinum, each structure is normal, has no enlarged lymph node shadow.Patient is without ill symptoms, and body, spirit, diet, sleeps all normal.Advise it to continue to take " three spend five sons six to fall apart in vain " further consultation after 12 months, CT checks left lung neoplasms and disappears, and all indexs are normal.It is advised to continue to strengthen treatment drug withdrawal in 6 months.Follow up a case by regular visits to alive tumor after 2 years not recur.
Case 3
Zhang 42 years old, has smoking history, occurs right side chest pain, and companion's cough and asthma, becomes thin weak.Be diagnosed as right lung peripheral to provincial hospital through CT and tissue pathology checking, differentiated squamous-cell carcinomas in genus, lump scope 5.2cm × 4.0cm, right breast is with a small amount of bloody pleural fluid.After examine out of admiration for a famous person, advise its " three spend five sons six to fall apart in vain " the taking the embodiment of the present invention each 9g every day of 2 mixing in water for oral taking sooner or later.Further consultation after 1 month, chest pain, the symptoms such as cough obviously alleviate.Advise it to continue clothes " three spend five sons six to fall apart in vain " after 12 months, various symptom is eliminated.Through X sheet, CT examination, hydrothorax and tumor disappearance.Follow up a case by regular visits to alive tumor after 2 years not recur.
Case 4
Wang, man, 67 years old, patient coughed uncomfortable in chest, 2 months out of breath.Look at certain hospital CT and show, left lung posterior lobe section shows multiple lesser tubercle, is fused into greater tubercle, high density focus, about 7cm, CT value 20HU, and upper left lung tumor 7cm × 3.3cm is diagnosed as left lung occupying lesion, neoplasm in lung, bronchitis, emphysema.Examine out of admiration for a famous person.Disease: cough, out of breath, chest pain, spiritlessness and weakness, becomes thin obviously, indigestion and loss of appetite, advises it to take " three spend five sons six to fall apart in vain " of the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.Further consultation after taking medicine 1 month.Stable disease, the symptoms such as check lump has no increase, and cough is out of breath, chest pain, weak obviously alleviate, and advise it to continue to take.Treat further consultation after 12 months.Check display: upper left lung neoplasms, neoplasm disappears all, and non-form size is all normal, does not find new focus.Advise it to consolidate again to take medicine 6 months.Follow up a case by regular visits to after 2 years, be still living and in good health and do not recur.
Case 5
Liu, man, 45 years old, has smoking history, obviously cough 3 months, when examining, patient is with uncomfortable in chest, and chest pain is out of breath, and sputum mixed with blood silk, becomes thin, weak, heating, lip is purple dark, and right cervical lymph node enlargement is as egg, and breast CT checks lump 3.2cm × 3.5cm near right lung door.It is advised to take " three spend five sons six to fall apart in vain " of the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.After one week, body temperature is normal, and uncomfortable in chest, chest pain, alleviates; Sputum mixed with blood silk is controlled.After taking medicine 1 month, cervical region mass reduction is extremely as Fructus Jujubae size, and CT checks, and right lung lump 2.2cm × 2.9cm, clinical symptoms is eliminated all.Continue to take " three spend five sons six to fall apart in vain " to further consultation after 9 months, neck region lump, right lung lump all disappears, and without uncomfortable, advises it to continue after treatment of taking medicine.Take medicine after 12 months, patient, spirit muscle power, diet sleep all recovers normal, without any discomfort.Consolidate again drug withdrawal after half a year.Alive recurrence is followed up a case by regular visits to after 3 years.
Case 6
Zhang, there is right side chest pain in female 42 years old, companion's cough, asthma, becomes thin, weak, chest x-ray is made film, CT and histopathological examination are diagnosed as in right lung peripheral and break up adenocarcinoma, lump scope 5.2cm × 4.1cm, and right lung is with middle amount bloody pleural fluid, it is advised to take " three spend five sons six to fall apart in vain " of the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.Further consultation after 1 month, chest pain, the clinical symptoms such as cough obviously alleviate, and spirit takes a turn for the better, and appetite is prosperous.After taking medicine 10 months, various symptom is eliminated, and through CT examination, hydrothorax and tumor disappearance, advise its after treatment drug withdrawal in 6 months again.Follow up a case by regular visits to after 2 years, alive, without any tumor-related symptoms.
Case 7
Zhao, female, 52 years old, occur right side chest pain, cough uncomfortable in chest, becomes thin weak, low grade fever, right cervical region monoblock is as large in Fructus Jujubae, makes film through X, CT and histopathological examination, be diagnosed as right lung peripheral type carcinoma of lung, differentiated squamous-cell carcinomas in genus, the right breast of lump scope 4.2cm × 3.5cm is with a small amount of bloody pleural fluid, it is advised to take " three spend five sons six to fall apart in vain " of the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.The clinical symptoms such as after 1 month, further consultation is uncomfortable in chest, cough obviously alleviate, and low grade fever is eliminated, and suddenly feel weak, neck region lump is contracted to soybean grain size, advises it to continue to take medicine.Further consultation after 10 months, all clinical symptoms and neck region lump disappear, CT examination hydrothorax and tumor disappearance, advise its after treatment drug withdrawal in 6 months again, follow up a case by regular visits to alive after 5 years.And there is not tumor-related symptoms.
Case 8
Qi, female 65 years old, patient coughs, asthma, left side chest pain 3 months, through certain hospital CT and histopathological examination, is diagnosed as the peripheral pulmonary carcinoma of left lung, break up adenocarcinoma in genus, the left breast of lump scope 3.6cm × 3.5cm with a small amount of hydrothorax, because being reluctant to perform an operation and chemicotherapy is examined.It is advised to take " three spend five sons six to fall apart in vain " of the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.Further consultation after 1 month, cough chest pain obviously alleviates, and spirit takes a turn for the better, and muscle power strengthens, and body weight increases, and CT examination mass reduction is to 2.4cm × 2.3cm, and hydrothorax disappears.It is advised to continue to take medicine.Further consultation after 6 months, tumor-related symptoms is slight, spirit, and diet, sleeps all good, and chest x-ray is made film, and mass reduction is to 1.5cm × 1.0cm, rear because of the drug withdrawal voluntarily of family's reason, advises its emotion that keeps pleasant.
Case 9
Lee, female 57 years old, has smoking history, and cough increases the weight of 3 months, does not give attention, and on the right side of rear appearance, chest pain asthma, coughs frothy sputum, accompany weak, become thin, and anorexia is gone to a doctor.Be diagnosed as right lung central type carcinoma of lung through chest X film making CT and histopathology cytolgical examination, in genus, break up adenocarcinoma.Lump 2.9cm × 2.4cm near right lung door, advises it to take " three spend five sons six to fall apart in vain " of the embodiment of the present invention, each 9g morning and evening every day 2 mixing in water for oral taking.Further consultation after 2 months, various clinical symptom disappearance, spirit takes a turn for the better, and appetite increases, and muscle power strengthens, and body weight increases, and chest x-ray is made film, and mass reduction is to 1.2cm × .0.8cm.After adhere to taking medicine after 12 months, further consultation, without any discomfort symptom, breast CT check lump disappear.After advise its after treatment drug withdrawal after 6 months again, take good care of voluntarily.Follow up a case by regular visits to and be still living and in good health, without tumor-related symptoms for 5 years.
Visible by above clinical case, Chinese medicine preparation three of the present invention spends five sons six to be dispersed in treatment pulmonary carcinoma in vain or lung tumors aspect has obvious clinical efficacy, therapeutic effect is obvious, have no side effect, therapeutic process is simple and safe, adheres to oral, need not carry out traditional radiation and chemotherapy formality, decrease misery and the medical expense of patient, substantially prolongs the life-span of patient.
Chinese medicine three of the present invention spends white the faling apart of five sons six to have following significant advantage:
(1) take the lead in " Tibetan medicine " as " monarch drug " for cancer and the dialectical compatibility of Chinese medicine.Compared with medicine in the past, novel formula, drug effect is remarkable, safety non-toxic more, verifiedly can reach obvious good efficacy.
(2) take the lead in " analogy being got as method " and " physicopsychic training techniques " principle applies in the Chinese medicine of Therapeutic cancer, meet the highest dialectical aim that treats of Huangdi's Internal Classics " behaving according to the law of YIN YANG; close in physicopsychic training techniques ", it is the innovation of Chinese medical discrimination philosophizing mode, thus make Chinese medicine preparation of the present invention for cancer more accurate, onset is rapider, cures more thorough.
Specifically, the lung five elements belong to gold, are three yin meridians of foot, main gas, and its matter is light clearly, and its color is white, and as fornix, be the canopy of the five internal organs, Xuan Fasu falls, and with kidney mutual generation between metal and water, breathe expiration and inspiration, complete the ascending, descending, exiting and entering of mechanism of qi.
In Chinese medicine of the present invention, the monarch drug " three flowers " of compatibility has matter light clearly, and light weight raises up, and throws with gas phase with lung, directly enters fornix.Its number spending three tastes to answer Eight Diagrams congenital from hexagram, its position upper, color be red should sick position at the blood system of lung.Monarch drug is impelled to go deep into lungs, through cancerous tissue.The ministerial drug " five sons " of compatibility is got its matter and is heavily dropped, and the therapeutic method to keep the adverse QI flowing downwards of astringing the lung, improving inspiration by invigorating kidney-QI returns kidney, and mothers and sons connect, lifting mechanism of qi.Its number gets five, the number xun, one of the Eight Diagrams hexagram of answering Eight Diagrams congenital, and xun, one of the Eight Diagrams is wind, and wind is that gas is dynamic, answers ascending or descending movement of vital Qi to come in and go out and moves, impel QI movement being in harmonious way, fall cancer poison of falling.Adjuvant drug " six is white " the Bai Yiying lung of compatibility, is beneficial in the up lung of medicine gesture.Its number gets six, the number bank six of answering Eight Diagrams congenital, to answer kidney water, mutual generation between metal and water.Merit, in solid lung training unit, is beneficial to again lung qi lifting expiration and inspiration.
(3) take the lead in adopting " two principles " prescription, compare Chinese medicine, lung cancer therapy effect is more definite.Specifically, Chinese medicine preparation of the present invention composition not only meets the traditional Chinese medical science " principle-method-recipe-medicines ", the principles of formulating prescriptions of " dialectical execute it ", and confirms through " modern pharmacological research ", clearly has anticancerly to kill cancer composition.There are 16 taste Chinese medicines to be have the anticancer Chinese medicine killing cancer composition through modern pharmacology checking in Chinese medicine preparation of the present invention, verifiedly substantially reduce the course for the treatment of for cancer.
(4) Chinese medicine preparation of the present invention is oral type powder, there is the meaning of " loose evil ", there is drug effect and play feature rapidly, specifically avoid the caused indivedual effective ingredient of decoction decocting and lost efficacy, it also avoid modern Chinese medicine purification technique and destroy the inherent rock-steady structure of Chinese medicine, cause the drawback that ingredient is unbalance.Meet the functional principle of Chinese medicine " letter, tests, just, honest and clean " simultaneously.
Should be understood that, above-mentioned detailed description of the invention of the present invention only for exemplary illustration or explain principle of the present invention, and is not construed as limiting the invention.Therefore, any amendment made when without departing from the spirit and scope of the present invention, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.In addition, claims of the present invention be intended to contain fall into claims scope and border or this scope and border equivalents in whole change and modification.
Claims (4)
1. a Chinese medicine three for the treatment of pulmonary carcinoma spends five sons six to fall apart in vain, and it is made up of the component of following mass fraction:
Saussurea involucrata Kar. et Kir. et Maxim. spend 25 parts, Flos Lonicerae 25 parts, Stigma Croci 25 parts, Galla Chinensis 20 parts, Semen Lepidii (Semen Descurainiae) 20 parts, Semen Strychni 20 parts, Fructus Schisandrae Chinensis 20 parts, Radix Semiaquilegiae 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, Cortex Mori 15 parts, Herba Solani Lyrati 15 parts, Herba Hedyotidis Diffusae 15 parts, Alumen 15 parts, 10 parts, scorpion tail, Scolopendra 10 parts, stir-baked SQUAMA MANITIS 10 parts.
2. according to claim 1 three spend five sons six to fall apart in vain, the component dosage of one course for the treatment of is:
Saussurea involucrata Kar. et Kir. et Maxim. flower 25g, Flos Lonicerae 25g, Stigma Croci 25g, Galla Chinensis 20g, Semen Lepidii (Semen Descurainiae) 20g, Semen Strychni 20g, Fructus Schisandrae Chinensis 20g, Radix Semiaquilegiae 20g, Rhizoma Atractylodis Macrocephalae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Cortex Mori 15g, Herba Solani Lyrati 15g, Herba Hedyotidis Diffusae 15g, Alumen 15g, scorpion tail 10g, Scolopendra 10g, stir-baked SQUAMA MANITIS 10g.
3. the preparation technology that five sons six are loose in vain spent by the Chinese medicine three for the treatment of pulmonary carcinoma, comprises the steps:
Saussurea involucrata Kar. et Kir. et Maxim. is spent 25 parts, Flos Lonicerae 25 parts and Stigma Croci 25 parts dry in the shade;
By Semen Strychni 20 parts decocting in water peeling, section is dried, with Oleum Sesami burned to yellow skin;
By Galla Chinensis 20 parts, Semen Lepidii (Semen Descurainiae) 20 parts, Fructus Schisandrae Chinensis 20 parts, Radix Semiaquilegiae 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, Cortex Mori 15 parts, Herba Solani Lyrati 15 parts, Herba Hedyotidis Diffusae 15 parts, 10 parts, scorpion tail, Scolopendra 10 parts and stir-baked SQUAMA MANITIS 10 parts oven dry;
The above-mentioned each medical material processed is mixed with Alumen 15 parts;
The mixture pulverizer of above-mentioned each medical material is pulverized repeatedly, until reach the medicated powder of more than 40 orders.
4. the Chinese medicine three according to any one of claim 1-2 spends five sons six to be dispersed in vain for the preparation of the application in the product for the treatment of pulmonary carcinoma.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1422640A (en) * | 2001-12-05 | 2003-06-11 | 李佩文 | Medicine for treating lung cancer and its preparation method |
| CN101049484A (en) * | 2007-05-14 | 2007-10-10 | 郝来勤 | Strong effective Chinese traditional medicine for treating lung cancer and other various cancers |
| CN102397490A (en) * | 2010-09-10 | 2012-04-04 | 高菲 | Preparation method of traditional Chinese medicinal prescription for treating lung cancer |
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| CN1422640A (en) * | 2001-12-05 | 2003-06-11 | 李佩文 | Medicine for treating lung cancer and its preparation method |
| CN101049484A (en) * | 2007-05-14 | 2007-10-10 | 郝来勤 | Strong effective Chinese traditional medicine for treating lung cancer and other various cancers |
| CN102397490A (en) * | 2010-09-10 | 2012-04-04 | 高菲 | Preparation method of traditional Chinese medicinal prescription for treating lung cancer |
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