CN106173627A - One regulate the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage and preparation processing method - Google Patents

One regulate the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage and preparation processing method Download PDF

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Publication number
CN106173627A
CN106173627A CN201610234328.9A CN201610234328A CN106173627A CN 106173627 A CN106173627 A CN 106173627A CN 201610234328 A CN201610234328 A CN 201610234328A CN 106173627 A CN106173627 A CN 106173627A
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parts
vitis viniferae
herba dendrobii
fresh
fructus
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温从字
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Zhejiang Yu Chen Pharmaceutical Co Ltd
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Zhejiang Yu Chen Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/02Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/60Sweeteners
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses the one of the present invention to regulate the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage, be made up of the raw material of following weight portion: new fresh Herba Dendrobii 10 20 parts, Fructus Vitis viniferae 10 20 parts, Pollen Tyjphae 5 15 parts, Oletum Trogopterori 5 15 parts, Rhizoma Corydalis 5 15 parts, Fructus Crataegi 20 30 parts, Radix Salviae Miltiorrhizae 5 10 parts, Radix Puerariae 5 15 parts, Fructus Aurantii 5 12 parts, Radix Achyranthis Bidentatae 5 15 parts, Anisodus carniolicoides C.Y.Wu et C.Chen 5 16 parts, Pericarpium Trichosanthis 5 10 parts, Os Draconis 5 15 parts, Cortex et Radix Polygalae 5 15 parts, Mel, water are appropriate.The invention have the advantage that having of inventive formulation regulate the flow of vital energy, intestinal stasis relieving, blood stasis dispelling, the function such as pain relieving, carry and drink conveniently, improve body immunity, defying age, eliminating toxin and beautifying the skin, cure the disease strengthens the beverage of body immunity simultaneously, and the shelf-life is up to 12 years.

Description

One regulate the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage and preparation processing method
Technical field
The present invention relates to one regulate the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage, in particular, relate to one and regulate the flow of vital energy intestinal stasis relieving blood stasis dispelling Pain material formula and preparation method thereof technical field.
Background technology
The most traditional beverage, only focuses on mouthfeel, is of low nutritive value, do not have regulate the flow of vital energy, intestinal stasis relieving, blood stasis dispelling, pain relieving preventing and treating gas Stagnant, blood stasis, tongue limit have the symptom such as purpura, weak, loss of appetite, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing spleen Stomach, drop three-hypers, prevent and treat diabetes and anti-cancer, the function of the aspect such as anticancer, it is impossible to release the sufferings of client, and traditional herbal tea leads to Crossing Traditional medicine infusion, flavour of a drug weight mouthfeel is poor, it is impossible to preserve for a long time.The most not yet occur a kind of in good taste, improve self and increase Add the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously.
Summary of the invention
The present invention is directed to the deficiency of existing product, and provide a kind of fresh juice beverage to regulate the effect of human physiological functions, This beverage have be easily absorbed by the human body, medicinal function is notable, delicious flavour, good mouthfeel, improve self and increase the wriggling of the intestines and stomach, Cure the disease and strengthen the one of the advantages such as body immunity simultaneously and regulate the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage.
One is regulated the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage, is made up of the raw material of following weight portion: new fresh Herba Dendrobii 10-20 part, Fructus Vitis viniferae 10-20 part, Pollen Tyjphae 5-15 part, Oletum Trogopterori 5-15 part, Rhizoma Corydalis 5-15 part, Fructus Crataegi 20-30 part, Radix Salviae Miltiorrhizae 5-10 part, Radix Puerariae 5- 15 parts, Fructus Aurantii 5-12 part, Radix Achyranthis Bidentatae 5-15 part, Anisodus carniolicoides C.Y.Wu et C.Chen 5-16 part, Pericarpium Trichosanthis 5-10 part, Os Draconis 5-15 part, Cortex et Radix Polygalae 5-15 part, fish Fish glue 5-10 part, Mel, water are appropriate;
The preparation processing method of described a kind of intestinal stasis relieving blood-activating analgetic beverage of regulating the flow of vital energy, comprises the following steps;
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby;
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20~30r/s;After standing 10 minutes, add the fresh bar of Herba Dendrobii The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80~100r/s, stands 10min; After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100~ 150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber;The warm water that new fresh grape is put into 50-60 DEG C again cleans dry After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by;
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby;
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35 Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby;After extracting Matrix Solution It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution Obtain Matrix Solution II;
E, take Pollen Tyjphae, Oletum Trogopterori, Rhizoma Corydalis, Fructus Crataegi, Radix Salviae Miltiorrhizae, Radix Puerariae, Fructus Aurantii, Radix Achyranthis Bidentatae, Anisodus carniolicoides C.Y.Wu et C.Chen, Pericarpium Trichosanthis, Os Draconis, will Far, after Air Bladder pseudosciaenae seu Acipenser mix homogeneously adds 30-60 DEG C of warm water soaking 10 minutes, putting into reach in freezer ,-10~-20 DEG C, freezing 10-20 divides Clock, forms freezing medicine block, freezing medicine block boiling is extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carry out infusion 10-20 minute;Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes;For the third time Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, obtains matrix Solution III is standby;
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank;Take Matrix Solution II through mesh Number be 100 mesh fine filter filter after put into material-compound tank;Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh In material-compound tank;
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is: Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae;
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial, Packaged vial puts into temperature 100~120 DEG C, 1.5MP, sterilization in 15~21 minutes steam ovens, packaging, vanning.
Further: step B) in, after new fresh grape cleans up, put into reach in freezer, at the freezing 5-10 in-10~-20 DEG C Minute, make Fructus Vitis viniferae freeze, after taking out nature defrosting, then carry out Fructus Vitis viniferae meat and Pericarpium Vitis viniferae detached job.
Further: step H) described in material-compound tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, Oleum Vitis viniferae Weight proportion be 10:0.2~0.8:5~10:0.5.
Pollen Tyjphae, sweet, flat, return liver, pericardium channel, hemostasis, blood stasis dispelling, treating stranguria.
Oletum Trogopterori, sweet, temperature, promoting blood circulation to remove blood stasis, have a pain for trusted subordinate's congestion.
Rhizoma Corydalis, warm in nature, acrid in the mouth is bitter, enters the heart, spleen, liver, lung, is blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain.
Fructus Crataegi, sour in the mouth is sweet. slightly warm in nature, and return taste Liver Channel, have promoting digestion and removing stagnation, effect of promoting blood circulation to remove blood stasis.
Radix Salviae Miltiorrhizae, has blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, and clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.
Radix Puerariae, sweet, pungent, cool.There are expelling pathogenic factors from muscles for reducing heat, rash, promoting the production of body fluid to quench thirst, the merit of yang invigorating antidiarrheal.
Fructus Aurantii, regulating the flow of QI to ease the stomach, the stagnant relieving distension of row, control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, weight after dysentery.
Radix Achyranthis Bidentatae, uses dissipating blood stasis blood, subduing inflammation.
Anisodus carniolicoides C.Y.Wu et C.Chen, blood-regulating prescription, there is blood stasis dispersing and deswelling, analgesic hemostatic effect.
Pericarpium Trichosanthis, Qinghua heat-phlegm, promoting the circulation of QI the chest stuffiness relieving, for phlegm-heat cough, hypochondriac pain uncomfortable in chest.
Os Draconis, tranquilizing mind, arresting collape syndrome by astringents, the merit of astringent or styptic treatment for spontaneous sweating lower vital essence.
Cortex et Radix Polygalae, Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, detumescence.The insomnia and dreamful sleep caused for disarmony between the heart and kidney, forgetful palpitation with fear, staring spells, Expectoration is not well.
By have above multiple health care natural tradition medicinal and edible Chinese medicine share, have regulate the flow of vital energy, intestinal stasis relieving, blood stasis dispelling, Effect of pain relieving, has the treatment stagnation of QI, there are purpura, weak, the merit of loss of appetite, fatigue in blood stasis, tongue limit.Sieved by great many of experiments Select the proportioning of each component, scientific and reasonable;And whole preparation technology is rationally and extract drugs rate efficiency is high, can retain former well Effective ingredient in material, does not bring any impurity into, has no side effect.
The invention has the beneficial effects as follows:
1, the formula of the present invention, has promoting the production of body fluid to quench thirst, gastric acid secretion, helps digest, and health body-building has calm nerves and declines Weak, lessen fatigue, containing various trace elements such as calcium, ferrum, zinc, selenium, sodium etc., raising body immunity, defying age, toxin expelling are supported Face, nourish taste, three-hypers drops, to prevent and treat diabetes and anti-cancer, the aspect such as anticancer the most powerful, regulates human physiological functions.
2, the present invention is rich in anthocyanidin, it is possible to protection human body is from the damage of free radical, it is possible to strengthens blood vessel elasticity, relax Blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect;Immune system ability can be strengthened, there is strong anti-oxidation, resist Suddenly change, alleviate the function such as hepatosis, protection cardiovascular;
3, Pollen Tyjphae, Oletum Trogopterori, Rhizoma Corydalis, Fructus Crataegi, Radix Salviae Miltiorrhizae, Radix Puerariae, Fructus Aurantii, Radix Achyranthis Bidentatae, Anisodus carniolicoides C.Y.Wu et C.Chen, Pericarpium Trichosanthis, Os Draconis, will are added Remote wait Chinese herbal medicine have regulate the flow of vital energy, intestinal stasis relieving, blood stasis dispelling, the function such as pain relieving.
4, the products taste that the production technology of the present invention and preparation method draw is sour-sweet tasty and refreshing, rich in dendrobium polysaccharide, has The highest health care and medical value, long-term drink can with YIN nourishing skin care, change skin colour, defying age, life lengthening, and Carrying and drink conveniently, improve self and increase the wriggling of the intestines and stomach, cure the disease and strengthen the beverage of body immunity simultaneously, the shelf-life is up to 1- 2 years.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, in order to those skilled in the art knows more about The present invention, but and it is not so limited the present invention.
Embodiment 1
One is regulated the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage, is made up of the raw material of following weight portion: new fresh Herba Dendrobii 15 parts, Fructus Vitis viniferae 15 parts, raw Pollen Typhae 10 parts, Oletum Trogopterori 10 parts, Rhizoma Corydalis 10 parts, Fructus Crataegi 25 parts, Radix Salviae Miltiorrhizae 8 parts, Radix Puerariae 10 parts, Fructus Aurantii 10 parts, Radix Achyranthis Bidentatae 10 parts, seven Li dissipate 10 parts, Pericarpium Trichosanthis 10 parts, Os Draconis 10 parts, Cortex et Radix Polygalae 10 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water appropriate;
The preparation processing method of a kind of intestinal stasis relieving blood-activating analgetic beverage of regulating the flow of vital energy, described preparation method comprises the following steps;
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby;
Fresh for the Herba Dendrobii cleaned up bar is put into microwave oven by B, keeps temperature 50-60 DEG C, carries out heating 10 minutes, further take out Put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content 52 of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time DEG C Chinese liquor, time 15min, the rotating speed of juice extractor is 30r/s;After standing 10 minutes, add the steaming of Herba Dendrobii fresh bar weight 2.5 times Distilled water, for the second time juice extractor time 15min, juice extractor rotating speed is 80r/s, stands 10min;After carry out third time squeeze the juice, add The distilled water of Herba Dendrobii fresh bar weight 3-5 times, time 30min, juice extractor rotating speed is 150r/s, by fresh for Herba Dendrobii bar juice and fiber mistake Filter separate, make the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, broken cell rate reaches more than 80%, obtain new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber;Again new fresh grape is put into after the warm water of 55 DEG C cleans up, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated Stand-by;After new fresh grape cleans up, put into reach in freezer ,-10 ~-20 DEG C of freezings 10 minutes, make Fructus Vitis viniferae freeze, take out certainly After so thawing, then carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job.
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 120 in tank Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby;
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 6 times of weight, stirring is smashed to 100 mesh, 30-35 DEG C of temperature Degree lower seal preserves 24h, sterilizing, filters, puts into unglazed hermetically sealed can, obtain Matrix Solution standby;Extract the Fructus Vitis viniferae after Matrix Solution It is the cellulase of 0.5-0.7% that skin and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, keeps 35 DEG C, water soluble dietary fiber can be extracted after 24h enzymolysis further, water soluble dietary fiber is added Matrix Solution and obtains Matrix Solution II;;Rich in anthocyanidin in Pericarpium Vitis viniferae, it is possible to protection human body is from the damage of free radical, it is possible to enhancing blood vessel elasticity, Lax blood vessel, increases systemic blood circulation, has certain blood pressure reduction effect;Immune system ability can be strengthened, there is strong antioxygen Change, mutation, alleviate hepatosis, protection function, Pericarpium Vitis viniferae and the Herba Dendrobii fresh bar fiber such as cardiovascular together with stir smash through Anthocyanidin mentioned by hydromel, can protect the quality of anthocyanidin while farthest extracting anthocyanidin.By water solublity meals Food fiber adds Matrix Solution and obtains Matrix Solution II, can increase effect of the wriggling of the intestines and stomach, it is ensured that metabolic waste is normally discharged External;Adsorb various metabolic waste, be allowed to normally excrete, improve the comprehensive utilization value of Herba Dendrobii.
E, take Pollen Tyjphae, Oletum Trogopterori, Rhizoma Corydalis, Fructus Crataegi, Radix Salviae Miltiorrhizae, Radix Puerariae, Fructus Aurantii, Radix Achyranthis Bidentatae, Anisodus carniolicoides C.Y.Wu et C.Chen, Pericarpium Trichosanthis, Os Draconis, After Cortex et Radix Polygalae, Air Bladder pseudosciaenae seu Acipenser mix homogeneously add 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer ,-10~-20 DEG C of freezings 20 points Clock, forms freezing medicine block, freezing medicine block boiling is extracted 3 times, add 1-2 times amount water for the first time, and temperature keeps 100-120 DEG C, carry out infusion 10-20 minute;Second time adds 6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes;Third time adds 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, obtains matrix molten Liquid III is standby;Chinese medicine foamed good after after freezing, cell wall crystallization ruptures, and forms freezing medicine block, then makes through high temperature infusion The composition of Chinese medicine farthest extracts.
F, take Matrix Solution I through instantaneous high-temperature 120 DEG C, 1-2 minute, put into material-compound tank;Take Matrix Solution II through mesh Number be 100 mesh fine filter filter after put into material-compound tank;Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh In material-compound tank;
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is: Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae;Supercritical extraction can be Extract under room temperature 37 DEG C and CO2 gas blanket, effectively prevent oxidation and the loss of heat-sensitive substance.Therefore, The effective ingredient of medicinal plants is remain in extract, and can be high boiling point, low volatility, the easy material being pyrolyzed the lowest Extract under its boiling temperature;
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, and described material-compound tank endobasal-body solution I, matrix are molten Liquid II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.5:6:0.5., seal through bottle capper and load vial In, packaged vial puts into temperature 100~120 DEG C, 1.5MP, sterilization in 15~21 minutes steam ovens, packaging, dress Case, carries and drinks conveniently, and the shelf-life is up to 1-2.
Embodiment 2
One is regulated the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage, is made up of the raw material of following weight portion: be made up of the raw material of following weight portion: by The raw material of following weight portion is made: new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Pollen Tyjphae 5 parts, Oletum Trogopterori 5 parts, Rhizoma Corydalis 5 parts, Fructus Crataegi 20 parts, Radix Salviae Miltiorrhizae 5 parts, Radix Puerariae 5 parts, Fructus Aurantii 5 parts, Radix Achyranthis Bidentatae 5 parts, Anisodus carniolicoides C.Y.Wu et C.Chen 5 parts, Pericarpium Trichosanthis 5 parts, Os Draconis 5 parts, Cortex et Radix Polygalae 5 parts, Air Bladder pseudosciaenae seu Acipenser 5 parts, Mel, water appropriate;Processing method is with embodiment 1.
Embodiment 3
One is regulated the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage, is made up of the raw material of following weight portion: be made up of the raw material of following weight portion: new Fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Pollen Tyjphae 15 parts, Oletum Trogopterori 15 parts, Rhizoma Corydalis 15 parts, Fructus Crataegi 30 parts, Radix Salviae Miltiorrhizae 10 parts, Radix Puerariae 15 Part, Fructus Aurantii 12 parts, Radix Achyranthis Bidentatae 15 parts, Anisodus carniolicoides C.Y.Wu et C.Chen 16 parts, Pericarpium Trichosanthis 10 parts, Os Draconis 15 parts, Cortex et Radix Polygalae 15 parts, 10 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water In right amount;Processing method is with embodiment 1.
Clinical experiment divides three parts:
(1) animal acute toxicity and chronic toxicity experiment:
1, animal acute toxicity test
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 medicated tea add the medicated tea powder paste that rice flour is made.
Experimental animal: regular grade NIH mice, body weight 18g ± 2g, male and female half and half.
Method and result:
By three kinds of each 50g of medicated tea, add rice flour.Experiment mice is randomly divided into three groups of male and female half and half, respectively three kinds of medicated tea of feeding Powder is stuck with paste, volume 1ml/10g body weight, and close observation 8 hours is also noted down, and continues to observe 7 days;In 7 days, mice is without death, OK For vivaciously, food ration is as usual, and hair color light is without loose dirt, without fainting from fear addicted to saliva, and eye, mouth, nose, ear and crissum secretions without exception, Without the rotten toe that docks.5 execution of selection from three groups respectively, finding of naked eye: the important organs such as the heart, liver, lung, gastric and thymus, not See abnormal change, show that two kinds of these nutritive powders are all without acute toxicity.
2, long-term toxicity test for animals
Medicine: the embodiment of the present invention 1, embodiment 2 and embodiment 3 gained medicated tea add the medicated tea powder paste that rice flour is made.
Animal: regular grade SD rat, body weight 200g ± 10g, male and female half and half.
Method and result:
The configuration that three kinds of medicated tea powder are stuck with paste: be divided into high, medium and low three dosage groups, respectively the 200 of edible for patients amount, 100, 50g;Experimental mouse is randomly divided into three groups, and the medicated tea powder that feeding modulates continuously respectively is stuck with paste, and continuous feeding 40 days observes animal General toxic reaction and the order of severity, place after death by rule of operation check each position, and carry out hematology, ALT, BUN and the heart, The pathological examination of the main organs such as liver, spleen, lung, kidney, stomach;
Through long-term feeding, all there is not toxic reaction in two groups of rats.Growth promoter is good.Macroscopic appearance and main organs have no Abnormal.Peripheral hemogram and Serum ALT, BUN compare with matched group without pathologic change.The pathological replacement heart, liver, spleen, lung, kidney, stomach Deng the most significant change, it is understood that through proved by pathology, three kinds of medicated tea powder are stuck with paste and showed animal without chronic toxicity.
By two above toxicity test, it was demonstrated that the medicated tea that the present invention is made by embodiment 1, embodiment 2 and embodiment 3 is Safety, have no side effect, can be used to clinical patients is carried out clinical trial.
3, the embodiment of the present invention drinks effect research:
(1) investigation method:
1. crowd is drunk: general population
2. Ganderwa: 20 days
3. number is drunk: 50 people
4. drinking method: 3 times for each person every day, each 300mL
5. index: after drinking, substantially there are purpura, weak, loss of appetite, food stagnation in sensation easily fatigue, the stagnation of QI, blood stasis, tongue limit not Disappear, anorexia, the transference cure such as middle gas not province, and mouthfeel is the most sour-sweet for effective;Sensation easily fatigue, the stagnation of QI, blood after drinking The stasis of blood, tongue limit have purpura, weak, loss of appetite;Food stagnation does not disappears, anorexia, middle gas do not save remission, and mouthfeel is the most sour-sweet then It is designated as effectively.It is invalid to be then designated as without obvious comfort after drinking.
(2) survey result
Survey result is shown in Table 1.Be test result indicate that by table 1, embodiment 1,2,3 has the respondent of 98% to feel that the present invention is carried The beverage mouthfeel of confession is the most sour-sweet, and above-mentioned clinical symptom disappearance or be eased, the respondent of only 2% drink after without substantially Increase comfort.
The each embodiment of table 1 drinks effect research table
Group/effect Obvious effective rate (number) Effective percentage (number) Inefficiency (number)
Embodiment 1 44%(22) 54%(27) 2%(1)
Embodiment 2 42%(21) 56%(28) 2%(1)
Embodiment 3 42%(21) 56%(28) 2%(1)
Embodiment contrast groups A
Comparative example 4,5,6 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing is traditional side of boiling Method;The investigation method of using method and using effect is with above.
Table 2 embodiment contrast groups A drinks effect research
Group/effect Obvious effective rate (number) Effective percentage (number) Inefficiency (number)
Comparative example 4 36%(18) 40%(20) 24%(12)
Comparative example 5 40%(20) 40%(20) 20%(10)
Comparative example 6 46%(23) 34%(17) 20%(10)
Embodiment contrast groups B
Comparative example 7,8,9 is added without the nutrition such as new fresh Herba Dendrobii, Fructus Vitis viniferae, Mel, water soluble dietary fiber and Oleum Vitis viniferae and becomes Point, according to the raw material that the Chinese medicine part of embodiment 1,2,3 above is original, preparation for processing uses in embodiment 1 The preparation processing method of step E;The investigation method of using method and using effect is with above.
Table 3 embodiment contrast groups B drinks effect research
Group/effect Obvious effective rate (number) Effective percentage (number) Inefficiency (number)
Comparative example 7 32%(16) 56%(28) 12%(6)
Comparative example 8 28%(14) 52%(31) 10%(5)
Comparative example 9 36%(18) 52%(26) 12%(6)
Embodiment contrast groups C
The processing method of comparative example 10,11,12 respectively corresponding embodiment 1,2,3 and formula, different be formula in Without Air Bladder pseudosciaenae seu Acipenser composition;The investigation method of using method and using effect is with above.
Table 4 embodiment contrast groups C drinks effect research
Group/effect Obvious effective rate (number) Effective percentage (number) Inefficiency (number)
Comparative example 10 44%(22) 46%(23) 10%(5)
Comparative example 11 38%(19) 50%(25) 12%(6)
Comparative example 12 40%(20) 48%(24) 12%(6)
Conclusion:
Contrasted by table 2 and table 1 and can be seen that
The inefficient number of embodiment contrast groups A is about 10 times of embodiment 1,2,3;This shows Chinese crude drug formula of the present invention And between the nutritional labeling such as water soluble dietary fiber and Oleum Vitis viniferae, creating the most collaborative pharmacological action, aqueous soluble dietary is fine Dimension increases effect of the wriggling of the intestines and stomach and promotes the human body absorption to ingredient, it is ensured that metabolic waste normally excretes, additionally The anthocyanidin that contains in Pericarpium Vitis viniferae, resveratrol, have strong anti-oxidation, mutation, alleviate hepatosis, protection cardiovascular etc. Function, strengthens immune system ability;Associate with Chinese medicine and improve assimilation effect and improve the mouthfeel of Chinese medicine, through the essence of the present invention simultaneously The extraction of heart configuration and at utmost ingredient, Chinese crude drug formula of the present invention and preparation method occur in that beat all technology Effect.
Table 2 and table 3 contrast can be seen that
About inefficient number is embodiment contrast groups B 2 times of embodiment contrast groups A, embodiment contrast groups B and traditional Embodiment contrast groups A of boiling method has compared significant raising at therapeutic effect, and this shows that Chinese crude drug of the present invention is through step The preparation processing method of rapid E has had significant raising than traditional boiling method, the extraction degree of active ingredient.
Table 1 is compared with table 4:
The formula of embodiment contrast groups C does not contains Air Bladder pseudosciaenae seu Acipenser, and the invalid number of embodiment contrast groups C is 5 times of left sides of embodiment 1,2,3 Right;And effective percentage number has and has declined;Containing abundant collagen protein and omega 3 unsaturated fatty acid in Air Bladder pseudosciaenae seu Acipenser, right Blood fat controls useful, can strengthen gastrointestinal digestive and absorptive functions, improves appetite, is conducive to preventing and treating inappetence, anorexia, digestion The diseases such as bad, abdominal distention, constipation, show Air Bladder pseudosciaenae seu Acipenser serve in formula collaborative and priming return through effect, Air Bladder pseudosciaenae seu Acipenser is in formula Application effect achieves unexpected technique effect.
In sum, a kind of intestinal stasis relieving blood-activating analgetic beverage of regulating the flow of vital energy that the present invention provides has sour-sweet mouthfeel, has again simultaneously Have treatment easily fatigue, the stagnation of QI, blood stasis, there is purpura on tongue limit, weak, loss of appetite, food stagnation do not disappear, anorexia, middle gas do not save Merit, improve body immunity, defying age, eliminating toxin and beautifying the skin, nourishing taste, drop three-hypers, prevent and treat diabetes and anti-cancer, the side such as anticancer Face is the most powerful.And all raw materials is all from medicine-food two-purpose natural plants, have no side effect.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For Yuan, under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should It is considered as protection scope of the present invention.

Claims (5)

1. an intestinal stasis relieving blood-activating analgetic beverage of regulating the flow of vital energy, it is characterised in that be made up of the raw material of following weight portion: new fresh Herba Dendrobii 10- 20 parts, Fructus Vitis viniferae 10-20 part, Pollen Tyjphae 5-15 part, Oletum Trogopterori 5-15 part, Rhizoma Corydalis 5-15 part, Fructus Crataegi 20-30 part, Radix Salviae Miltiorrhizae 5-10 Part, Radix Puerariae 5-15 part, Fructus Aurantii 5-12 part, Radix Achyranthis Bidentatae 5-15 part, Anisodus carniolicoides C.Y.Wu et C.Chen 5-16 part, Pericarpium Trichosanthis 5-10 part, Os Draconis 5-15 part, Cortex et Radix Polygalae 5-15 part, Air Bladder pseudosciaenae seu Acipenser 5-10 part, Mel, water are appropriate;
The preparation processing method of described a kind of intestinal stasis relieving blood-activating analgetic beverage of regulating the flow of vital energy, comprises the following steps;
A, fresh for Herba Dendrobii bar is put into service sink, remove surface clay stain, the fresh bar of screening high-quality Herba Dendrobii, dry standby;
B, fresh for the Herba Dendrobii cleaned up bar is put into microwave oven, keep temperature 50-60 DEG C, carry out heating 10 minutes, then take Go out to put into rotating centrifugal juice extractor, carry out three times and squeeze the juice, add the alcohol content of Herba Dendrobii fresh bar weight 0.1-0.5 times for the first time The Chinese liquor of 52-60 DEG C, time 10-15min, the rotating speed of juice extractor is 20~30r/s;After standing 10 minutes, add the fresh bar of Herba Dendrobii The distilled water of weight 2-3 times, for the second time juice extractor time 10-15min, juice extractor rotating speed is 80~100r/s, stands 10min; After carry out third time squeeze the juice, add Herba Dendrobii fresh bar weight 3-5 times distilled water, time 20-30min, juice extractor rotating speed be 100~ 150r/s, separates fresh for Herba Dendrobii bar juice with fiber filter, makes the fiber separation rate of the fresh bar of Herba Dendrobii reach more than 95%, cell damage Rate reaches more than 80%, obtains new fresh Herba Dendrobii juice and Herba Dendrobii fresh bar fiber;The warm water that new fresh grape is put into 50-60 DEG C again cleans dry After Jing, Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae are separated stand-by;
C, Herba Dendrobii fresh bar juice is put into and is put in pressure pan with Fructus Vitis viniferae meat, keeps pressure 0.5MP, temperature to keep 100-150 in tank Degree, carries out infusion 10 minutes, obtains Matrix Solution I standby;
D, fresh for the Herba Dendrobii of separation bar fiber and Pericarpium Vitis viniferae are put into unglazed hermetically sealed can, in hermetically sealed can, add that to be equivalent to Herba Dendrobii fresh Bar fiber and the Mel of Pericarpium Vitis viniferae gross weight 20-30% and the distilled water of 5-10 times of weight, stirring is smashed to 100 mesh, at 30-35 Seal at a temperature of DEG C and preserve 24h, sterilizing, filter, put into unglazed hermetically sealed can, obtain Matrix Solution standby;After extracting Matrix Solution It is the cellulase of 0.5-0.7% that Pericarpium Vitis viniferae and Herba Dendrobii fresh bar fiber add mass volume ratio, adds the water of the mass ratio of 1:10, Keep 35 DEG C, water soluble dietary fiber can be extracted further after 24h enzymolysis, water soluble dietary fiber is added Matrix Solution Obtain Matrix Solution II;
E, take Pollen Tyjphae, Oletum Trogopterori, Rhizoma Corydalis, Fructus Crataegi, Radix Salviae Miltiorrhizae, Radix Puerariae, Fructus Aurantii, Radix Achyranthis Bidentatae, Anisodus carniolicoides C.Y.Wu et C.Chen, Pericarpium Trichosanthis, Os Draconis, will Far, Air Bladder pseudosciaenae seu Acipenser;After mix homogeneously adds 30-60 DEG C of warm water soaking 10 minutes, put into reach in freezer, at the freezing 10-20 in-10~-20 DEG C Minute, forming freezing medicine block, freezing medicine block boiling is extracted 3 times, add 1-2 times amount water for the first time, temperature keeps 100-120 DEG C, carry out infusion 10-20 minute;Second time adds 4-6 times amount water, and temperature keeps 80-100 DEG C, carries out infusion 10 minutes;For the third time Adding 6-10 times amount water, temperature keeps 120-150 DEG C, carries out infusion 30 minutes, filters, is concentrated into the 1/2 of original volume, obtains matrix Solution III is standby;
F, take Matrix Solution I through instantaneous high-temperature 110-130 DEG C, 1-2 minute, put into material-compound tank;Take Matrix Solution II through mesh Number be 100 mesh fine filter filter after put into material-compound tank;Take Matrix Solution III again to put into after the fine filter filter that mesh number is 60 mesh In material-compound tank;
G, by Semen Vitis viniferae through vacuum outgas, then use CO2 supercritical fluid extraction, the condition of CO2 supercritical fluid extraction is: Extracting pressure 45MPa, extraction temperature 35-45 DEG C, extraction time 30min, isolated Oleum Vitis viniferae;
H, three kinds of Matrix Solutions are stirring evenly and then adding into Oleum Vitis viniferae at material-compound tank, seal through bottle capper and load in vial, Packaged vial puts into temperature 100~120 DEG C, 1.5MP, sterilization in 15~21 minutes steam ovens, packaging, vanning.
One the most according to claim 1 is regulated the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage, it is characterised in that step B) in, fresh Portugal After grape clean up, put into reach in freezer ,-10~-20 DEG C freezing 5-10 minute, make Fructus Vitis viniferae freeze, take out after nature thaws, Carry out Fructus Vitis viniferae meat, Pericarpium Vitis viniferae, Semen Vitis viniferae detached job again.
One the most according to claim 1 is regulated the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage, it is characterised in that step H) described in dispensing Tank endobasal-body solution I, Matrix Solution II, Matrix Solution III, the weight proportion of Oleum Vitis viniferae are 10:0.2~0.8:5~10: 0.5。
One the most according to claim 1 is regulated the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage, it is characterised in that former by following weight portion Material is made: new fresh Herba Dendrobii 10 parts, Fructus Vitis viniferae 10 parts, Pollen Tyjphae 5 parts, Oletum Trogopterori 5 parts, Rhizoma Corydalis 5 parts, Fructus Crataegi 20 parts, Radix Salviae Miltiorrhizae 5 parts, Radix Puerariae 5 parts, Fructus Aurantii 5 parts, Radix Achyranthis Bidentatae 5 parts, Anisodus carniolicoides C.Y.Wu et C.Chen 5 parts, Pericarpium Trichosanthis 5 parts, Os Draconis 5 parts, Cortex et Radix Polygalae 5 parts, 5 parts of Air Bladder pseudosciaenae seu Acipenser, Mel, water are fitted Amount.
One the most according to claim 1 is regulated the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage, it is characterised in that former by following weight portion Material is made: new fresh Herba Dendrobii 20 parts, Fructus Vitis viniferae 20 parts, Pollen Tyjphae 15 parts, Oletum Trogopterori 15 parts, Rhizoma Corydalis 15 parts, Fructus Crataegi 30 parts, Radix Salviae Miltiorrhizae 10 Part, Radix Puerariae 15 parts, Fructus Aurantii 12 parts, Radix Achyranthis Bidentatae 15 parts, Anisodus carniolicoides C.Y.Wu et C.Chen 16 parts, Pericarpium Trichosanthis 10 parts, Os Draconis 15 parts, Cortex et Radix Polygalae 15 parts, Air Bladder pseudosciaenae seu Acipenser 10 Part, Mel, water are appropriate.
CN201610234328.9A 2016-04-17 2016-04-17 One regulate the flow of vital energy intestinal stasis relieving blood-activating analgetic beverage and preparation processing method Pending CN106173627A (en)

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Citations (1)

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CN103300450A (en) * 2013-06-14 2013-09-18 浙江大学 Preparation method of raw dendrobium officinale pulp beverage

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CN103300450A (en) * 2013-06-14 2013-09-18 浙江大学 Preparation method of raw dendrobium officinale pulp beverage

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