CN106164645B - 用于诊断流体系统并且判定流式细胞仪的数据处理设置的系统和方法 - Google Patents

用于诊断流体系统并且判定流式细胞仪的数据处理设置的系统和方法 Download PDF

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CN106164645B
CN106164645B CN201580011249.5A CN201580011249A CN106164645B CN 106164645 B CN106164645 B CN 106164645B CN 201580011249 A CN201580011249 A CN 201580011249A CN 106164645 B CN106164645 B CN 106164645B
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CN106164645A (zh
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G·卡达查克
J·阿克尔隆德
J·马尔金
M·沃德
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Life Technologies Corp
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1012—Calibrating particle analysers; References therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1012—Calibrating particle analysers; References therefor
    • G01N2015/1014—Constitution of reference particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1026—Recognising analyser failures, e.g. bubbles; Quality control for particle analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1027—Determining speed or velocity of a particle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1438—Using two lasers in succession

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  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201580011249.5A 2014-03-06 2015-02-03 用于诊断流体系统并且判定流式细胞仪的数据处理设置的系统和方法 Active CN106164645B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461948547P 2014-03-06 2014-03-06
US61/948,547 2014-03-06
US201462056646P 2014-09-29 2014-09-29
US62/056,646 2014-09-29
PCT/US2015/014210 WO2015134139A1 (en) 2014-03-06 2015-02-03 Systems and methods for diagnosing a fluidics system and determining data processing settings for a flow cytometer

Publications (2)

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CN106164645A CN106164645A (zh) 2016-11-23
CN106164645B true CN106164645B (zh) 2019-10-18

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US (2) US10001434B2 (enExample)
EP (1) EP3114458B1 (enExample)
JP (1) JP2017511884A (enExample)
KR (1) KR20160130754A (enExample)
CN (1) CN106164645B (enExample)
AU (1) AU2015225730A1 (enExample)
MX (1) MX2016011482A (enExample)
RU (1) RU2016132999A (enExample)
SG (1) SG11201606189UA (enExample)
WO (1) WO2015134139A1 (enExample)

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US9857284B1 (en) * 2013-07-15 2018-01-02 Stratedigm, Inc. Method and apparatus for detection and measurement of particles with a wide dynamic range of measurement
EP3114458B1 (en) 2014-03-06 2024-08-21 Life Technologies Corporation Methods for diagnosing a fluidics system
US9863864B2 (en) * 2015-09-15 2018-01-09 Bio-Rad Technologies, Inc. Threshold selector for flow cytometer
SG11201908847TA (en) 2017-03-31 2019-10-30 Life Technologies Corp Apparatuses, systems and methods for imaging flow cytometry
DE102018119081A1 (de) * 2018-08-06 2020-02-06 Foshan Sensicfusion Technology Co., Ltd. Ein Verfahren und eine Vorrichtung zum Zählen von Luftpartikeln
KR102103080B1 (ko) * 2018-10-17 2020-04-22 빌리브마이크론(주) 입자 측정 시스템 및 그 측정 방법
SE543406C2 (en) * 2019-05-15 2021-01-05 Nanosized Sweden Ab Water impurity measurements with dynamic light scattering
CN110715892A (zh) * 2019-09-19 2020-01-21 中国科学院苏州生物医学工程技术研究所 基于多激光流式细胞仪的数据处理方法及系统、流式细胞仪控制系统
US20250180461A1 (en) * 2022-01-31 2025-06-05 Sony Group Corporation Biological sample analysis system, method for setting light data acquisition section in biological sample analysis system, and information processing device
WO2023163813A1 (en) * 2022-02-24 2023-08-31 Becton, Dickinson And Company Methods and systems for evaluating flow cytometer data for the presence of a coincident event
EP4484920A1 (en) * 2022-02-25 2025-01-01 On-Chip Biotechnologies Co., Ltd. In-droplet particle detection method, method for fractioning/dispensing droplet including particles, method for removing particles to outside from droplet after dispensing, and device therefor
CN120577172B (zh) * 2025-08-05 2025-11-14 西安电子科技大学 一种通道可配置的液体颗粒脉冲幅度检测方法及相关装置

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US5199576A (en) * 1991-04-05 1993-04-06 University Of Rochester System for flexibly sorting particles
US5682038A (en) * 1995-04-06 1997-10-28 Becton Dickinson And Company Fluorescent-particle analyzer with timing alignment for analog pulse subtraction of fluorescent pulses arising from different excitation locations
AU2003902319A0 (en) * 2003-05-14 2003-05-29 Garrett Thermal Systems Limited Laser video detector
KR101166180B1 (ko) * 2003-08-13 2012-07-18 루미넥스 코포레이션 유세포 분석기식 측정 시스템의 하나 이상의 파라미터의 제어 방법
US8817244B2 (en) * 2010-01-15 2014-08-26 Mitsui Engineering & Shipbuilding Co., Ltd. Fluorescence measurement device and fluorescence measurement method
EP2545357B1 (en) * 2010-03-10 2021-06-02 Beckman Coulter, Inc. Generating pulse parameters in a particle analyzer
CN103068456B (zh) * 2010-05-10 2015-09-16 热费希尔科学公司 颗粒物监视器
EP2671065B1 (en) * 2011-02-04 2019-07-10 Cytonome/ST, LLC Particle sorting apparatus and method
EP2724144B1 (en) * 2011-08-25 2018-04-11 Sony Corporation Characterization of motion-related error in a stream of moving micro-entities
EP3114458B1 (en) 2014-03-06 2024-08-21 Life Technologies Corporation Methods for diagnosing a fluidics system

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Publication number Publication date
EP3114458A1 (en) 2017-01-11
EP3114458B1 (en) 2024-08-21
US20180335375A1 (en) 2018-11-22
SG11201606189UA (en) 2016-09-29
RU2016132999A3 (enExample) 2018-09-19
MX2016011482A (es) 2016-12-20
US20150253235A1 (en) 2015-09-10
US10001434B2 (en) 2018-06-19
CN106164645A (zh) 2016-11-23
JP2017511884A (ja) 2017-04-27
WO2015134139A1 (en) 2015-09-11
KR20160130754A (ko) 2016-11-14
US10520418B2 (en) 2019-12-31
AU2015225730A1 (en) 2016-10-27
RU2016132999A (ru) 2018-04-09

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