CN106164645B - 用于诊断流体系统并且判定流式细胞仪的数据处理设置的系统和方法 - Google Patents

用于诊断流体系统并且判定流式细胞仪的数据处理设置的系统和方法 Download PDF

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CN106164645B
CN106164645B CN201580011249.5A CN201580011249A CN106164645B CN 106164645 B CN106164645 B CN 106164645B CN 201580011249 A CN201580011249 A CN 201580011249A CN 106164645 B CN106164645 B CN 106164645B
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CN106164645A (zh
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G·卡达查克
J·阿克尔隆德
J·马尔金
M·沃德
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Life Technologies Corp
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/1012Calibrating particle analysers; References therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/1012Calibrating particle analysers; References therefor
    • G01N2015/1014Constitution of reference particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1026Recognising analyser failures, e.g. bubbles; Quality control for particle analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1027Determining speed or velocity of a particle
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434Optical arrangements
    • G01N2015/1438Using two lasers in succession

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Signal Processing (AREA)
  • Engineering & Computer Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201580011249.5A 2014-03-06 2015-02-03 用于诊断流体系统并且判定流式细胞仪的数据处理设置的系统和方法 Active CN106164645B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461948547P 2014-03-06 2014-03-06
US61/948,547 2014-03-06
US201462056646P 2014-09-29 2014-09-29
US62/056,646 2014-09-29
PCT/US2015/014210 WO2015134139A1 (en) 2014-03-06 2015-02-03 Systems and methods for diagnosing a fluidics system and determining data processing settings for a flow cytometer

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CN106164645A CN106164645A (zh) 2016-11-23
CN106164645B true CN106164645B (zh) 2019-10-18

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US (2) US10001434B2 (enExample)
EP (1) EP3114458B1 (enExample)
JP (1) JP2017511884A (enExample)
KR (1) KR20160130754A (enExample)
CN (1) CN106164645B (enExample)
AU (1) AU2015225730A1 (enExample)
MX (1) MX2016011482A (enExample)
RU (1) RU2016132999A (enExample)
SG (1) SG11201606189UA (enExample)
WO (1) WO2015134139A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9857284B1 (en) * 2013-07-15 2018-01-02 Stratedigm, Inc. Method and apparatus for detection and measurement of particles with a wide dynamic range of measurement
KR20160130754A (ko) 2014-03-06 2016-11-14 라이프 테크놀로지스 코포레이션 유체 시스템을 진단하고 유동 세포분석기를 위한 데이터 처리 설정을 결정하는 시스템 및 방법
US9863864B2 (en) 2015-09-15 2018-01-09 Bio-Rad Technologies, Inc. Threshold selector for flow cytometer
SG11201908847TA (en) 2017-03-31 2019-10-30 Life Technologies Corp Apparatuses, systems and methods for imaging flow cytometry
DE102018119081A1 (de) * 2018-08-06 2020-02-06 Foshan Sensicfusion Technology Co., Ltd. Ein Verfahren und eine Vorrichtung zum Zählen von Luftpartikeln
KR102103080B1 (ko) * 2018-10-17 2020-04-22 빌리브마이크론(주) 입자 측정 시스템 및 그 측정 방법
SE543406C2 (en) * 2019-05-15 2021-01-05 Nanosized Sweden Ab Water impurity measurements with dynamic light scattering
CN110715892A (zh) * 2019-09-19 2020-01-21 中国科学院苏州生物医学工程技术研究所 基于多激光流式细胞仪的数据处理方法及系统、流式细胞仪控制系统
WO2023145551A1 (ja) * 2022-01-31 2023-08-03 ソニーグループ株式会社 生体試料分析システム、生体試料分析システムにおける光データ取得区間の設定方法、及び情報処理装置
JP2025508860A (ja) * 2022-02-24 2025-04-10 ベクトン・ディキンソン・アンド・カンパニー フローサイトメータデータを同時発生事象の有無について評価するための方法及びシステム
US20250172487A1 (en) * 2022-02-25 2025-05-29 On-Chip Biotechnologies Co., Ltd. In-droplet particle detection method, method for fractioning/dispensing droplet including particles, method for removing particles to outside from droplet after dispensing, and device therefor
WO2025030122A1 (en) * 2023-08-03 2025-02-06 Life Technologies Corporation Systems and methods for off-axis bubble detection
CN120577172B (zh) * 2025-08-05 2025-11-14 西安电子科技大学 一种通道可配置的液体颗粒脉冲幅度检测方法及相关装置

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5199576A (en) * 1991-04-05 1993-04-06 University Of Rochester System for flexibly sorting particles
US5682038A (en) * 1995-04-06 1997-10-28 Becton Dickinson And Company Fluorescent-particle analyzer with timing alignment for analog pulse subtraction of fluorescent pulses arising from different excitation locations
AU2003902319A0 (en) * 2003-05-14 2003-05-29 Garrett Thermal Systems Limited Laser video detector
KR101135138B1 (ko) * 2003-08-13 2012-04-16 루미넥스 코포레이션 유세포 분석기식 측정 시스템의 하나 이상의 파라미터의제어 방법
KR20120103659A (ko) * 2010-01-15 2012-09-19 미쯔이 죠센 가부시키가이샤 형광 측정 장치 및 형광 측정 방법
CN102792147B (zh) 2010-03-10 2015-05-13 贝克曼考尔特公司 在颗粒分析器中产生脉冲参数
US8726720B2 (en) * 2010-05-10 2014-05-20 Thermo Fisher Scientific Inc. Particulate matter monitor
US8705031B2 (en) * 2011-02-04 2014-04-22 Cytonome/St, Llc Particle sorting apparatus and method
US9897530B2 (en) 2011-08-25 2018-02-20 Sony Corporation Compensation of motion-related error in a stream of moving micro-entities
KR20160130754A (ko) 2014-03-06 2016-11-14 라이프 테크놀로지스 코포레이션 유체 시스템을 진단하고 유동 세포분석기를 위한 데이터 처리 설정을 결정하는 시스템 및 방법

Also Published As

Publication number Publication date
SG11201606189UA (en) 2016-09-29
WO2015134139A1 (en) 2015-09-11
CN106164645A (zh) 2016-11-23
EP3114458A1 (en) 2017-01-11
US10520418B2 (en) 2019-12-31
KR20160130754A (ko) 2016-11-14
RU2016132999A3 (enExample) 2018-09-19
EP3114458B1 (en) 2024-08-21
MX2016011482A (es) 2016-12-20
JP2017511884A (ja) 2017-04-27
US20180335375A1 (en) 2018-11-22
AU2015225730A1 (en) 2016-10-27
US20150253235A1 (en) 2015-09-10
RU2016132999A (ru) 2018-04-09
US10001434B2 (en) 2018-06-19

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