CN106138476A - A kind of Chinese medicinal capsule for treating acne - Google Patents

A kind of Chinese medicinal capsule for treating acne Download PDF

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CN106138476A
CN106138476A CN201610760548.5A CN201610760548A CN106138476A CN 106138476 A CN106138476 A CN 106138476A CN 201610760548 A CN201610760548 A CN 201610760548A CN 106138476 A CN106138476 A CN 106138476A
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parts
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radix
herba
leaf
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虞志秋
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    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/725Ziziphus, e.g. jujube
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K9/4841Filling excipients; Inactive ingredients

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Abstract

The invention discloses a kind of Chinese medicinal capsule for treating acne, the Chinese crude drug of following weight proportion be prepared from: Flos Chrysanthemi 7 parts, Radix Et Rhizoma Rhei 5 parts, Radix Salviae Miltiorrhizae 10 parts, Flos Caryophylli 9 parts, Cortex Magnoliae Officinalis 8 parts, Cortex Phellodendri 9 parts, Flos Lonicerae 8 parts, different leaf Gueldenstaedtia verna 5 parts, 6 parts of Cassia siamea leaf, Folium Alstoniae Scholaris 7 parts, Herba Gonostegiae hirtae 6 parts, Folium Ilicis Purpureae 8 parts, Maifanitum 14 parts, BAXIAGA 11 parts, Backhousia angustifolia halberd 13 parts, hide Herba Androsaces Umbellatae (Herba Androsaces Coccineae) 5 parts, without lobe Fructus Jujubae 9 parts, PIPER FLAVIFLORUM 4 parts, open country, Yunnan Radix Angelicae Sinensis 6 parts, radix jalalae root 12 parts, Crusta Penaeus seu Panulirus money 7 parts, Sibiraea angustata 11 parts, 10 parts of Radix Glycyrrhizae, Rhizoma Ligustici 10 parts.Clinical trial certificate, the present invention reasonable compatibility by Chinese crude drug, contribute to treating acne, and can effectively reduce complication, reach integrally-regulated and long-term effect good effects.

Description

A kind of Chinese medicinal capsule for treating acne
Technical field
The present invention relates to a kind of Chinese medicinal capsule, be specifically related to a kind of Chinese medicinal capsule for treating acne.
Background technology
A kind of hair follicle being apt to occur in face, neck, thoracic dorsal or buttocks etc. of acne and the chronic inflammatory skin disease of sebaceous gland. Primary disease is mainly in adolescence, and skin lesion is pimple conforming with hair follicle, blackhead, Whiteheads, abscess, cyst, knot Joints etc., easily happen over and over again, and severe patient can form depression or hypertrophic cicatrix, and the inflammation in deep can form huge abscess, more After can leave over cicatrix, course of disease delay difficulty is more.The primary disease cause of disease is the most fully aware of, may lead with endocrine disturbance, pilosebaceous unit The factors such as pipe dyskeratosis, microorganism infection, heredity, cosmetics use are relevant.Owing to acne is because of various and easily send out complication, Only rely on several taste medicine to be difficult to look after comprehensively, multi-medicament suitably must be coordinated, improve curative effect or reduce untoward reaction, to adapt to The treatment of the complicated state of an illness.In view of the various active composition interaction in vivo of various Chinese crude drugs is sufficiently complex, various medicines The change of the aspects such as pharmacokinetics in vivo and pharmacodynamics can produce various impacts, medicine to the interaction between medicine During combination, both may produce Synergistic drug effect, it is also possible to produce antagonism, and then cause Drug therapy declines or Endodontic failure, some drug combination also can make drug toxicity strengthen, cause untoward reaction;Even if drug combination makes effect increase By force, but the tolerant ability of body can be exceeded when therapeutical effect excessively strengthens, it is possible to cause untoward reaction, or even harm suffered from Person.Part research to treatment acne, the most easily problem appear to is that the compatibility of medicines in a prescription is unreasonable, usually toward plan Chinese medicinal formulae certainly It is only to cure mainly from some single or polypharmaceutic discrete function to remove to copy mechanically and apply indiscriminately Chinese medical theory, prescription with some pharmacodynamic index Flavour of a drug are arbitrarily added and subtracted, and cause prescription unreasonable, contradict with Chinese medical theory.
Summary of the invention
It is desirable to provide a kind of Chinese medicinal capsule for treating acne, by the reasonable compatibility of Chinese crude drug, contribute to Treatment acne, and can effectively prevent recurrence, reach integrally-regulated and long-term effect good effects.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicinal capsule for treating acne, is prepared from by the Chinese crude drug of following weight proportion: Flos Chrysanthemi 7 parts, Radix Et Rhizoma Rhei 5 Part, Radix Salviae Miltiorrhizae 10 parts, Flos Caryophylli 9 parts, Cortex Magnoliae Officinalis 8 parts, Cortex Phellodendri 9 parts, Flos Lonicerae 8 parts, different leaf Gueldenstaedtia verna 5 parts, 6 parts of Cassia siamea leaf, lamp-stand 7 parts of leaf, Herba Gonostegiae hirtae 6 parts, Folium Ilicis Purpureae 8 parts, Maifanitum 14 parts, BAXIAGA 11 parts, Backhousia angustifolia halberd 13 parts, hide Herba Androsaces Umbellatae (Herba Androsaces Coccineae) 5 parts, without lobe Fructus Jujubae 9 parts, PIPER FLAVIFLORUM 4 parts, open country, Yunnan Radix Angelicae Sinensis 6 parts, radix jalalae root 12 parts, Crusta Penaeus seu Panulirus money 7 parts, Sibiraea angustata 11 parts, 10 parts of Radix Glycyrrhizae, Rhizoma Ligustici 10 parts.
Preparation method is: mix after above-mentioned medical material goes the removal of impurity respectively, dries in sending into drying baker at a temperature of 120 DEG C Dry, it is ground into 100-130 mesh smalls, after disinfection by ultraviolet light, presses 0.5g/ grain load capsule, be finished product.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
Flos Chrysanthemi [source] this product is the dry capitulum of feverfew chrysanthemum.[nature and flavor] are sweet, bitter, are slightly cold.[return through] return lung, Liver Channel.[function cures mainly] dissipates wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, dizziness of having a headache, conjunctival congestion and swelling pain, eyes is dim-sighted.
Radix Et Rhizoma Rhei [source] this product is the dry root and rhizome of polygonum rheum palmatum.[nature and flavor] are bitter, cold.[return through] returns Spleen, stomach, large intestine, liver, pericardium channel.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant Stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, and traumatic injury damages Wound, external treatment burn due to hot liquid or fire;Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.
Radix Salviae Miltiorrhizae [source] this product is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.[nature and flavor] are bitter, are slightly cold.[return through] GUIXIN, Liver Channel.[function cures mainly] stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen amasss Poly-, chest and abdomen twinge, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia;Hepatosplenomegaly, angina pectoris.
Flos Caryophylli [source] this product is the dry flower of plant clove of myrtaceae.[nature and flavor] are pungent, temperature.[return through] return spleen, stomach, Lung, kidney channel.[function cures mainly] warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG.For Deficiency and coldness of spleen and stomach, singultus is vomitted, lack of appetite and vomiting, trusted subordinate's cold type of pain, Impotence due to deficiency of the kidney.
Cortex Magnoliae Officinalis [source] Magnoliacea plant Cortex Magnoliae Officinalis or the dry dried bark of magnolia officinalis rehd.et wils.var.biloba rehd.et wils., root bark and branch skin.[function cures mainly] is dry Wet expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.
Cortex Phellodendri [source] this product is the dry bark of rutaceae wampee or Cortex Phellodendri.[function cures mainly] heat clearing and damp drying, Pathogenic fire purging is except steaming, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, tinea pedis, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, skin infection swells Poison, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Flos Lonicerae [source] this product is dry flower or the first flower opened of band of caprifoliaceae plant Radix Ophiopogonis.[nature and flavor] are sweet, cold. [return through] returns lung, the heart, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, pyretic toxicity Dysentery, anemopyretic cold, epidemic febrile disease is generated heat.
Different leaf Gueldenstaedtia verna [source] pulse family different leaf Gueldenstaedtia verna, with all herbal medicine.[nature and flavor] are bitter, puckery, cold.[function cures mainly] Heat-clearing and toxic substances removing, diuresis.Harness the river the diseases such as swollen, carbuncle, furunculosis, tuberculous lymphadenitis.
The dry lobule of Cassia siamea leaf [source] leguminosae cassia plant Cassia siamea.[nature and flavor] bitter in the mouth, cold in nature, enter water, wind Tower.[function cures mainly] expelling wind and removing dampness, reducing swelling and alleviating pain, killing parasites for relieving itching.
The dry leaves of Folium Alstoniae Scholaris [source] Apocynaceae Alstonia plant sugar gum.[nature and flavor] bitter in the mouth, micro-puckery, Cold.[function cures mainly] Qinghuo Jiedu, reducing swelling and alleviating pain, relieving cough and resolving phlegm.
Herba Gonostegiae hirtae [source] is the whole herb with root of contrayerva Herba Gonostegiae Hirtae.[nature and flavor] sweetness and bitterness, cool.[function cures mainly] heat clearing away Removing toxic substances, spleen invigorating, hemostasis.Treatment skin ulcer, carbuncle, scrofula, dysentery, women leucorrhea, infantile malnutrition, spit blood, traumatic hemorrhage.
Folium Ilicis Purpureae [source] is the blade of holly plant Ilicis Purpureae.[nature and flavor] are pained, cold.[function cures mainly] controls scald, The long disunion of ulcer, thromboangiitis obliterans, acute and chronic bronchitis, pneumonia, urinary tract infection, bacillary dysentery, traumatic hemorrhage, freezes chilblain, chap Split.
Maifanitum [source] medical material Ji Yuan: for Acid-intermediate igneous rock rocks beschtauite.[nature and flavor] are sweet;Temperature; Nontoxic.[return through] liver;Stomach;Kidney channel.[function cures mainly] detoxicating and resolving stagnation of pathogens;Removing the necrotic tissue and promoting granulation;Except cold damp eliminating;The liver benefiting stomach invigorating;Invigorating blood circulation The stasis of blood;Diuresis fossil;Life lengthening.Main carbuncle carbuncle on the back;Acne;Eczema;Tinea pedis;Miliaria;Finger is chapped;Chloasma;Toothache;Oral cavity Ulcer;Rheumatic arthralgia;Lumbago and backache;Chronic hepatitis;Gastritis;Dysentery;Diabetes;Neurasthenia;Wound is red and swollen;Hypertension;Old Property sclerosis of blood vessels;Tumor;Lithangiuria.
BAXIAGA [source] Plantaginaceae plant comospore grandmother's sodium etc. belongs to the dry herb of kindred plant together.[nature and flavor] abnormal smells from the patient is bitter Taste, cold in nature.[function cures mainly] heat clearing away, more skin ulcer, granulation promoting, hemostasis, improving eyesight.It is widely used in skin ulcer clinically to treat, wound, inflammation, eye Disease.
Backhousia angustifolia halberd [source] is root bark and the leaf of Maguireothamnus speciosus Backhousia angustifolia halberd.[nature and flavor] bitter in the mouth, cool in nature.[function master Control] Qinghuo Jiedu, promoting the function of the gallbladder to alleviate jaundice, killing parasites for relieving itching, expelling pus and promoting granulation.Cure mainly jaundice, cholelithiasis, furuncle carbuncle furuncle abscess, skin pruritus, Macule.Scabies, eczema, Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) allergy, children's's skin infection does not closes up.
Hide the herb that Herba Androsaces Umbellatae (Herba Androsaces Coccineae) [source] is Ofthe Primulaceae Herba Androsaces integrae.[nature and flavor] bitter in the mouth, cold in nature.[function master Control] diuresis, dry Xieri Wusu Symptom, detumescence, kill glutinous.Treating edema, edema, joint Xieri Wusu Symptom is sick, anthrax, laryngopharynx swelling and pain.
Fructus Jujubae without lobe [source] is the fruit of Rhamnaceae plant brown fruit Fructus Jujubae.[nature and flavor] sour in the mouth, micro-puckery, cool in nature.[function cures mainly] Qinghuo Jiedu, killing parasites for relieving itching.Cure mainly furuncle carbuncle furuncle abscess, skin pruritus, macule, scabies, eczema, insect-bite.
PIPER FLAVIFLORUM [source] is the rattan of Piperaceae plant PIPER FLAVIFLORUM.[nature and flavor] taste is peppery, property heat.[function cures mainly] temperature Venting QI-blood.Dispersing cold for relieving pain, antipruritic.Cure mainly abdomen gastral cavity distending pain, dysmenorrhea, tinea.
Open country, open country, Yunnan Radix Angelicae Sinensis [source] Umbelliferae archangel Yunnan Radix Angelicae Sinensis, is used as medicine with root.Autumn and winter adopt root, clean and shine Dry.[nature and flavor] are pungent, temperature.[function cures mainly] promoting blood flow to regulate menstruation, nourishing blood for moistening dryness, laxation.For menoxenia, dysmenorrhea, blood stasis amenorrhea, Anemia, rheumatic arthritis, traumatic injury, dryness of the intestine constipation etc..
Radix jalalae root [source] is the dried root of convolvulaceous plant Bryonia dioica.[nature and flavor] two grades are xeothermic, sweet in the mouth.[function master Control] raw dry heat, attack and rush down dampness, cold-dispelling pain-relieving, detumescent of relieving oedema or abdominal distension through diuresis or purgation, the oldest cough, move back old heat, anthelmintic.Cure mainly raw property or kill liquid Matter disease, such as constipation, habitual constipation, hydrosarca, bowel obstruction, old headache, cold heating, insane disease, waist The back of the body is ached, sciatica, paralysis, facial paralysis, arthralgia, old coughs more than, and old heat is not moved back, and intestinal is infested.
Crusta Penaeus seu Panulirus money [source] medical material Ji Yuan: for the herb of Violaceae plant Taiwan common violet.[function cures mainly] spleen benefiting and stimulating the appetite;Dispel Wind cough-relieving;Promoting blood circulation to restore menstrual flow.It is depressed that main children's eats drink;Flu;Cough;Dysmenorrhea;Red collapse leucorrhea;Stomachache dysentery;Rheumatism.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, Stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, tired Idle weak, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
Rhizoma Ligustici [source] this product is Umbelliferae Ligustrum plant Rhizoma Ligustici or the dry rhizome of Rhizoma Ligustici and root.[nature and flavor] are pungent, Temperature.[return through] returns bladder warp.[function cures mainly] dispels the wind, cold expelling, dehumidifying, pain relieving.For anemofrigid cold, top, mountain peak pain, rheumatism limb Joint arthralgia pain.
Branch and leaf that Sibiraea angustata [source] is spent with Rosaceae Sibirae Sibiraea angustata and Xianbei an ancient nationality in China and infructescence be (band fruit Fruit branch) it is used as medicine.[function cures mainly] clearing away stomach-heat, aid digestion, regulation lipid metabolism.
Butterfly gardenful spring [source] medical material Ji Yuan: for herb or flower, the fruit of bloodroot Flos Papaveris rhoeadis.[nature and flavor] Bitter;Puckery;It is slightly cold;Poisonous.[return through] large intestine channel.[function cures mainly] antitussive;Analgesia;Antidiarrheal.Main cough;Migraine;Stomachache;Dysentery Disease.
Herba Murdanniae Divergentis [source] medical material Ji Yuan: for root or the Herb of Commelianaceae plant purple back of the body Herba Pyrolae.[nature and flavor] are sweet;Micro- Bitter;Flat.[function cures mainly] clearing away lung-heat to relieve cough;Invigorating the lung and the kidney;Regulating menstruation, hemostasis.Main cough due to lung-heat;The deficiency of vital energy is breathed with cough;Dizziness and tinnitus;Fracture; Spit blood.
Liquor Rosae Rugosae Distillata [source] is the distillate of rosaceous plant Flos Rosae Rugosae.[nature and flavor] are light;Flat.[return through] liver;Spleen;Stomach Warp.[function cures mainly] and in, skin care pool is sent out.Main hyperactive liver-QI attacking the stomach, distension and fullness in the abdomen pain, skin dried and withered hairs is withered.
The present invention compared with prior art, has the advantages that
1, the selected medicament composing prescription of the present invention, its drug component through dialectical compatibility, complements each other using, has synergism, Treatment to acne reaches treating both the principal and the secondary aspects of a disease at the same time.Prescription is particular about monarch, four natures and five flavors of drug lifting, BAXIAGA, radix jalalae root, narrow The 6 taste medical materials such as leaf bar halberd, Maifanitum, Sibiraea angustata are monarch drug altogether, play a leading role, control by acting on major target class in compound recipe Treat disease;Rhizoma Ligustici, it is ministerial drug without 8 taste medical materials such as lobe Fructus Jujubae, different leaf Gueldenstaedtia verna, Radix Salviae Miltiorrhizae, Crusta Penaeus seu Panulirus money, identical with monarch drug by acting on Target spot strengthen the pharmacological action of monarch drug, thus reduce monarch drug required dosage;Remaining is assistant, makes medical herbs, to improve monarch, ministerial drug Bioavailability, coordinate the activity of their each composition.Especially it is noted that the present inventor is through repetition test, and combine Pharmacological research is observed and is confirmed, adds Sibiraea angustata and can significantly alleviate cutaneous inflammatory lesion after Maifanitum mutually 5, suppresses local pigment deposition, anti- Only cicatrization.BAXIAGA, radix jalalae root, without lobe Fructus Jujubae three mutually 5, significantly inhibit that propionibacterium acnes infects only can be produced Special curative effect.The effect of Crusta Penaeus seu Panulirus Qian Kezeng Backhousia angustifolia halberd, accelerates to promote Pigmented disappearing.
2, the present invention is directed to pathogenesis of acne mechanism, launch treatment, in clinical practice from Mutiple Targets, too many levels, multipath Have rapid-action, determined curative effect, patient compliance are good, safe without toxic side effect, can significantly improve patient's autoimmunity, specimen Double controlling prevents recurrence, thus has wide potential applicability in clinical practice.
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Weigh: Flos Chrysanthemi 7 grams, Radix Et Rhizoma Rhei 5 grams, Radix Salviae Miltiorrhizae 10 grams, Flos Caryophylli 9 grams, Cortex Magnoliae Officinalis 8 grams, Cortex Phellodendri 9 grams, Flos Lonicerae 8 grams, different leaf rice mouth 5 grams of bag, 6 grams of Cassia siamea leaf, Folium Alstoniae Scholaris 7 grams, Herba Gonostegiae hirtae 6 grams, Folium Ilicis Purpureae 8 grams, Maifanitum 14 grams, BAXIAGA 11 grams, Backhousia angustifolia Halberd 13 grams, hide Herba Androsaces Umbellatae (Herba Androsaces Coccineae) 5 grams, without lobe Fructus Jujubae 9 grams, PIPER FLAVIFLORUM 4 grams, open country, Yunnan Radix Angelicae Sinensis 6 grams, radix jalalae root 12 grams, Crusta Penaeus seu Panulirus money 7 Gram, Sibiraea angustata 11 grams, 10 grams of Radix Glycyrrhizae, Rhizoma Ligustici 10 grams.
Preparation method is: mix after above-mentioned medical material goes the removal of impurity respectively, dries in sending into drying baker at a temperature of 120 DEG C Dry, it is ground into 100-130 mesh smalls, presses 0.5g/ grain after disinfection by ultraviolet light and load capsule, be finished product.
Usage and dosage: oral, every day 2 times, the most each 1 time, each 1, warm water delivery service after meal;Within 15 days, it is 1 course for the treatment of, Take 2 courses for the treatment of continuously.
Clinical data:
1, case selection:
In the patients with acne 40 example clinical observation of my institute's diagnosis and treatment since selecting 2013, clinical symptoms all meets acne diagnosis and treatment mark Accurate.Patient is randomly divided into treatment group and matched group two groups, treatment group 20 example, matched group 20 example.Treatment group and matched group two groups are sick The course of disease of example, degrees of symptoms are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes the Chinese medicinal capsule obtained by the embodiment of the present invention 1, oral, every day 2 times, the most each 1 time, each 1, meal Rear warm water delivery service;It within 15 days, it is 1 course for the treatment of.
Matched group Effect of Oral Metronidazole sheet 0.2g, every day 2 times;Tetracycline tablet 0.5g, every day 2 times, the scorching peaceful liniment of outer painting skin.Treat Journey is with treatment group.
2 courses for the treatment of are treated in smelting continuously, contrast two groups of curative effects.
3, efficacy determination:
(1) cure: erythra all disappears or only stays minority acne.
(2) take a turn for the better: erythra has and substantially disappears.
(3) do not heal: erythra is without substantially disappearing or new erythra constantly occurs.
4, result:
Selecting in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, cure 14 examples, take a turn for the better 5 examples, the most 1 example, cure rate 70%, always Effective percentage 95%.Average cure time 25 days.Healing and improvement patient are followed the tracks of and follows up a case by regular visits to 24 months, without 1 example recurrence.
Curing 10 examples in matched group, take a turn for the better 4 examples, the most 6 examples, cure rate 50%, total effective rate 70%.Average cure time 28 My god.Healing and improvement patient are followed the tracks of and follows up a case by regular visits to 24 months, 2 examples recurrences.
Result above shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Embodiment 2
Weigh: Flos Chrysanthemi 7 grams, Radix Et Rhizoma Rhei 5 grams, Radix Salviae Miltiorrhizae 10 grams, Flos Caryophylli 9 grams, Cortex Magnoliae Officinalis 8 grams, Cortex Phellodendri 9 grams, Flos Lonicerae 8 grams, different leaf rice mouth 5 grams of bag, 6 grams of Cassia siamea leaf, Folium Alstoniae Scholaris 7 grams, Herba Gonostegiae hirtae 6 grams, Folium Ilicis Purpureae 8 grams, Maifanitum 14 grams, BAXIAGA 11 grams, Backhousia angustifolia Halberd 13 grams, hide Herba Androsaces Umbellatae (Herba Androsaces Coccineae) 5 grams, without lobe Fructus Jujubae 9 grams, PIPER FLAVIFLORUM 4 grams, open country, Yunnan Radix Angelicae Sinensis 6 grams, radix jalalae root 12 grams, Crusta Penaeus seu Panulirus money 7 Gram, 10 grams of Radix Glycyrrhizae, Rhizoma Ligustici 10 grams.Preparation method is with embodiment 1.
In 10 patients with acne of the Chinese medicinal capsule that the selection embodiment of the present invention 2 is made, curing 6 examples, take a turn for the better 3 examples, and the most 1 Example, cure rate 50%, total effective rate 90%.Healing and improvement patient are followed the tracks of and follows up a case by regular visits to 24 months, 1 example recurrence.
Embodiment 3
Weigh: Flos Chrysanthemi 7 grams, Radix Et Rhizoma Rhei 5 grams, Radix Salviae Miltiorrhizae 10 grams, Flos Caryophylli 9 grams, Cortex Magnoliae Officinalis 8 grams, Cortex Phellodendri 9 grams, Flos Lonicerae 8 grams, different leaf rice mouth 5 grams of bag, 6 grams of Cassia siamea leaf, Folium Alstoniae Scholaris 7 grams, Herba Gonostegiae hirtae 6 grams, Folium Ilicis Purpureae 8 grams, Maifanitum 14 grams, Backhousia angustifolia halberd 13 grams, Tibetan point Ground 5 grams of prunus mume (sieb.) sieb.et zucc., PIPER FLAVIFLORUM 4 grams, open country, Yunnan Radix Angelicae Sinensis 6 grams, radix jalalae root 12 grams, Crusta Penaeus seu Panulirus money 7 grams, Sibiraea angustata 11 grams, 10 grams of Radix Glycyrrhizae, ligusticumic These 10 grams.Preparation method is with embodiment 1.
In 10 patients with acne of the Chinese medicinal capsule that the selection embodiment of the present invention 3 is made, curing 5 examples, take a turn for the better 2 examples, and the most 3 Example, cure rate 50%, total effective rate 70%.Healing and improvement patient are followed the tracks of and follows up a case by regular visits to 24 months, 2 examples recurrences.
Embodiment 4
Weigh: Flos Chrysanthemi 7 grams, Radix Et Rhizoma Rhei 5 grams, Radix Salviae Miltiorrhizae 10 grams, Flos Caryophylli 9 grams, Cortex Magnoliae Officinalis 8 grams, Cortex Phellodendri 9 grams, Flos Lonicerae 8 grams, different leaf rice mouth Bag 5 grams, Folium Ilicis Purpureae 8 grams, Maifanitum 14 grams, Backhousia angustifolia halberd 13 grams, hide Herba Androsaces Umbellatae (Herba Androsaces Coccineae) 5 grams, without lobe Fructus Jujubae 9 grams, PIPER FLAVIFLORUM 4 grams, cloud Nanye Radix Angelicae Sinensis 6 grams, radix jalalae root 12 grams, Crusta Penaeus seu Panulirus money 7 grams, Sibiraea angustata 11 grams, 10 grams of Radix Glycyrrhizae.Preparation method is with embodiment 1.
Embodiment 5
Weigh: Flos Chrysanthemi 7 grams, Radix Et Rhizoma Rhei 5 grams, Radix Salviae Miltiorrhizae 10 grams, Flos Caryophylli 9 grams, Cortex Magnoliae Officinalis 8 grams, Cortex Phellodendri 9 grams, Flos Lonicerae 8 grams, different leaf rice mouth 5 grams of bag, 6 grams of Cassia siamea leaf, Folium Alstoniae Scholaris 7 grams, Herba Gonostegiae hirtae 6 grams, Folium Ilicis Purpureae 8 grams, Maifanitum 14 grams, butterfly gardenful spring 5 grams, narrow leaf Bar halberd 13 grams, hide Herba Androsaces Umbellatae (Herba Androsaces Coccineae) 5 grams, without lobe Fructus Jujubae 9 grams, PIPER FLAVIFLORUM 4 grams, open country, Yunnan Radix Angelicae Sinensis 6 grams, radix jalalae root 12 grams, Sibiraea angustata 11 Gram, 10 grams of Radix Glycyrrhizae, Rhizoma Ligustici 10 grams.Preparation method is with embodiment 1.
Embodiment 6
Weigh: Flos Chrysanthemi 7 grams, Radix Et Rhizoma Rhei 5 grams, Radix Salviae Miltiorrhizae 10 grams, Flos Caryophylli 9 grams, Cortex Magnoliae Officinalis 8 grams, Cortex Phellodendri 9 grams, Flos Lonicerae 8 grams, different leaf rice mouth 5 grams of bag, butterfly gardenful spring 6 grams, Herba Murdanniae Divergentis 6 grams, Folium Ilicis Purpureae 8 grams, Maifanitum 14 grams, BAXIAGA 11 grams, Backhousia angustifolia halberd 13 grams, Tibetan Herba Androsaces Umbellatae (Herba Androsaces Coccineae) 5 grams, without lobe Fructus Jujubae 9 grams, PIPER FLAVIFLORUM 4 grams, open country, Yunnan Radix Angelicae Sinensis 6 grams, radix jalalae root 12 grams, Crusta Penaeus seu Panulirus money 7 grams, Sibiraea angustata 11 Gram, 10 grams of Radix Glycyrrhizae, Rhizoma Ligustici 10 grams.Preparation method is with embodiment 1.
Embodiment 7
Weigh: Flos Chrysanthemi 7 grams, Radix Et Rhizoma Rhei 5 grams, Radix Salviae Miltiorrhizae 10 grams, Flos Caryophylli 9 grams, Cortex Magnoliae Officinalis 8 grams, Cortex Phellodendri 9 grams, Flos Lonicerae 8 grams, different leaf rice mouth 5 grams of bag, butterfly gardenful spring 6 grams, Herba Murdanniae Divergentis 6 grams, 6 grams of Cassia siamea leaf, Folium Alstoniae Scholaris 7 grams, Herba Gonostegiae hirtae 6 grams, Folium Ilicis Purpureae 8 grams, wheat meal 14 grams of stone, BAXIAGA 11 grams, Backhousia angustifolia halberd 13 grams, hide Herba Androsaces Umbellatae (Herba Androsaces Coccineae) 5 grams, without lobe Fructus Jujubae 9 grams, PIPER FLAVIFLORUM 4 grams, open country, Yunnan Radix Angelicae Sinensis 6 Gram, radix jalalae root 12 grams, Crusta Penaeus seu Panulirus money 7 grams, Sibiraea angustata 11 grams, 10 grams of Radix Glycyrrhizae, Rhizoma Ligustici 10 grams.Preparation method is with embodiment 1.
Embodiment 8
Weigh: Liquor Rosae Rugosae Distillata 7 grams, Flos Chrysanthemi 7 grams, Radix Et Rhizoma Rhei 5 grams, Radix Salviae Miltiorrhizae 10 grams, Flos Caryophylli 9 grams, Cortex Magnoliae Officinalis 8 grams, Cortex Phellodendri 9 grams, Flos Lonicerae 8 Gram, different leaf Gueldenstaedtia verna 5 grams, the butterfly gardenful spring 6 grams, Herba Murdanniae Divergentis 6 grams, 6 grams of Cassia siamea leaf, Folium Alstoniae Scholaris 7 grams, Herba Gonostegiae hirtae 6 grams, Ilicis Purpureae 8 grams of leaf, Maifanitum 14 grams, BAXIAGA 11 grams, Backhousia angustifolia halberd 13 grams, hide Herba Androsaces Umbellatae (Herba Androsaces Coccineae) 5 grams, without lobe Fructus Jujubae 9 grams, PIPER FLAVIFLORUM 4 grams, cloud Nanye Radix Angelicae Sinensis 6 grams, radix jalalae root 12 grams, Crusta Penaeus seu Panulirus money 7 grams, Sibiraea angustata 11 grams, 10 grams of Radix Glycyrrhizae, Rhizoma Ligustici 10 grams.Preparation method is with implementing Example 1.
Selecting the patients with acne 20 example clinical observation in my institute's diagnosis and treatment, clinical symptoms all meets acne diagnosis and treatment standard.Patient It is randomly divided into 5 groups, takes the Chinese medicinal capsule that embodiment of the present invention 4-8 is made respectively, oral, every day 2 times, the most each 1 time, every time 1, warm water delivery service after meal, record curative effect is as follows:
Case Cure Take a turn for the better Do not heal Untoward reaction Recur in 2 years Average cure time
Embodiment 4 4 3 1 0 0 1 29 days
Embodiment 5 4 4 0 0 1 1 27 days
Embodiment 6 4 4 0 0 0 0 24 days
Embodiment 7 4 4 0 0 0 0 20 days
Embodiment 8 4 4 0 0 0 0 15 days
Obviously, the above embodiment of the present invention is only for clearly demonstrating example of the present invention, and is not to this The restriction of bright embodiment, such as the present invention is in addition to making capsule, can also be used with common technology and makes other peroral dosage forms.Phase Close Chinese medicine and pharmacology thereof all can be obtained by existing open source literature and network, it is also possible to the medical material by close effect is the most alternative. For those of ordinary skill in the field, the change of other multi-form can also be made on the basis of the above description Or variation.Here cannot all of embodiment be given exhaustive.Every belong to that technical scheme extended out aobvious And the change being clear to or variation are still in the row of protection scope of the present invention.

Claims (2)

1. the Chinese medicinal capsule being used for treating acne, it is characterised in that be prepared from by the Chinese crude drug of following weight proportion: chrysanthemum Spend 7 parts, Radix Et Rhizoma Rhei 5 parts, Radix Salviae Miltiorrhizae 10 parts, Flos Caryophylli 9 parts, Cortex Magnoliae Officinalis 8 parts, Cortex Phellodendri 9 parts, Flos Lonicerae 8 parts, different leaf Gueldenstaedtia verna 5 parts, Cassia siamea 6 parts of leaf, Folium Alstoniae Scholaris 7 parts, Herba Gonostegiae hirtae 6 parts, Folium Ilicis Purpureae 8 parts, Maifanitum 14 parts, BAXIAGA 11 parts, Backhousia angustifolia halberd 13 parts, some ground, Tibetan 5 parts of prunus mume (sieb.) sieb.et zucc., without lobe Fructus Jujubae 9 parts, PIPER FLAVIFLORUM 4 parts, open country, Yunnan Radix Angelicae Sinensis 6 parts, radix jalalae root 12 parts, Crusta Penaeus seu Panulirus money 7 parts, Sibiraea angustata 11 parts, sweet Grass 10 parts, Rhizoma Ligustici 10 parts.
The preparation method of a kind of Chinese medicinal capsule for treating acne the most according to claim 1, it is characterised in that by upper State after medical material goes the removal of impurity respectively and mix, dry at a temperature of 120 DEG C in sending into drying baker, be ground into 100-130 mesh smalls, warp Press 0.5g/ grain after disinfection by ultraviolet light and load capsule, be finished product.
CN201610760548.5A 2016-08-31 2016-08-31 A kind of Chinese medicinal capsule for treating acne Pending CN106138476A (en)

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