CN104826068A - Medicine for expelling wind and eliminating dampness and preparation method of medicine - Google Patents
Medicine for expelling wind and eliminating dampness and preparation method of medicine Download PDFInfo
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Abstract
The invention discloses a medicine for expelling wind and eliminating dampness and a preparation method of the medicine. The medicine is mainly prepared from ceratostigma, herb of cupleaf passion flower, caesalpinia cucullata, polygonum runcinatum, araliae cardatae, radix angelicae tuhuo, rhizoma drynariae, aconitum scaposum, hypericum attenuatum, astragalus membranaceus, habenaria dentate, pittosporum illicioides, dried ginger, indigofera stachyoides, panax japonicas, akebiaquinata, red onion, fissistigma bracteolatum and auxiliary materials. The medicine has the effects of regulating qi and blood, balancing yin and yang, expelling air cold, removing damp arthralgia and remarkably relieving pain, can be used for treating pain caused by cervical spondylosis, lumbar spondylosis, hyperostosis, rheumatoid arthritis, rheumatoid, periarthritis of shoulder, gout, puerperal fever and traumatic injury, and is remarkable in treatment effect and small in side effect.
Description
Technical field
The present invention relates to medicine of a kind of expelling wind and removing dampness and preparation method thereof, belong to the field of medicine technology.
Technical background
Rheumatism is medically the chronic pain of articulations digitorum manus and surrounding soft tissue's unknown cause thereof.Rheumatism then refers to that the different but common ground of a large class cause of disease is for involving joint and surrounding soft tissue, comprises the disease of flesh, ligament, synovial bursa, fascia.Arthropathy is outer still with swelling and moving obstacle apart from pain, in outbreak with alleviate the chronic course of disease alternately, some patients and can occur disabling and viscera function exhaustion in joint.Rheumatism is a kind of anaphylactic reaction that Hemolytic streptococcus causes.How otitis media, tonsillitis, pharyngitis, scarlet fever etc. occur in the sick 1-4 anniversary suffering from.Teenager because of resistance more weak, be easy to get this kind of disease.Also easily there is allergy in the people of body constitution difference, chance of falling ill is also many.
Lumbar muscle strain, traumatic injury are in daily life for some people seemingly homely food, Chinese traditional treatment lumbar muscle strain, traumatic injury have the history of several thousand, the introduction that ancient title " traumatic injury " is all wounds, many because of External Force Acting, or overexert when self fault and cause.The muscles and bones trauma that the traditional Chinese medical science causes in human body because of External Force Acting all, swelling and pain due to blood stasis, disharmony between QI and blood, blockage of main and collateral channels, so that internal organs are impaired etc., are referred to as traumatic injury.Its main pathology is that congestion is stopped up stagnant, and blood is held one's breath resistance, therefore with pain, swelling for main manifestations.Treatment is mainly with promoting blood circulation to remove obstruction in the collateral, and relaxing muscles and tendons and promoting circulation of QI, reducing swelling and alleviating pain is method, and curative effect is also comparatively obvious.
Arthritis is common, multiple and that disability rate is high immune disease.Joint swelling and pain sized by clinical main manifestations, distortion, even loses self care ability.
In the face of above-mentioned disease, though current Western medicine oral medicine has rapid-action and that analgesic activities is strong effect, side effect can cause gastrointestinal dysfunction, all there is infringement in various degree to heart, liver, kidney.Take orally and take effect slowly.Medicine for external use directly acts on affected part, sometimes causes illing skin allergy to damage even in various degree because drug level is too high.Therefore, a good effect, side effect is less, will be well received for rheumatism, traumatic injury and arthritic medicine.
Summary of the invention:
Technical problem to be solved by this invention is medicine providing a kind of expelling wind and removing dampness and preparation method thereof.Described medicine has and regulates QI and blood, Yin Yang balancing, cold-dispelling, effect except arthralgia chiefly caused by damp pathogen, can significantly alleviate various pain, be used for the treatment of cervical spondylosis, lumbar spondylosis, hyperosteogeny, rheumatic arthritis, rheumatoid, scapulohumeral periarthritis, gout, puerperal fever and traumatic injury; And evident in efficacy, side effect is little.
For solving the problems of the technologies described above, the present invention realizes by the following technical solutions: a kind of medicine of expelling wind and removing dampness, calculate by weight, primarily of Radix Ceratostigmatis mini 1-50 part, Herba Passiflorae Cupiformis 5-80 part, Radix Zanthoxyli Spinifolii 1-60 part, Radix Polygoni Runcinati 1-40 part, Araliae cardatae 1-70 part, Radix Angelicae Pubescentis 1-40 part, Rhizoma Drynariae 5-80 part, YIKOUXUE 1-40 part, Herba hyperici attenuati 10-110 part, Radix Astragali 1-70 part, twoflower rattlesnake plantain 1-60 part, pittosporm root 1-60 part, Rhizoma Zingiberis 1-110 part, Radix Lespedezae Buergeri 1-70 part, panax japonicus 1-50 part, Caulis Akebiae 1-40 part, Bulbus Eleutherines Plicatae 1-70 part, Radix Fissistigmatis Oldhamii 1-60 and adjuvant are prepared from.
The medicine of aforesaid expelling wind and removing dampness, calculate by weight, be prepared from primarily of Radix Ceratostigmatis mini 5-30 part, Herba Passiflorae Cupiformis 10-50 part, Radix Zanthoxyli Spinifolii 5-30 part, Radix Polygoni Runcinati 5-15 part, Araliae cardatae 5-40 part, Radix Angelicae Pubescentis 5-15 part, Rhizoma Drynariae 10-50 part, YIKOUXUE 5-15 part, Herba hyperici attenuati 30-90 part, Radix Astragali 10-50 part, twoflower rattlesnake plantain 10-40 part, pittosporm root 5-30 part, Rhizoma Zingiberis 20-90 part, Radix Lespedezae Buergeri 10-50 part, panax japonicus 10-30 part, Caulis Akebiae 5-15 part, Bulbus Eleutherines Plicatae 10-40 part, Radix Fissistigmatis Oldhamii 5-25 and adjuvant.
In the medicine of aforesaid expelling wind and removing dampness, calculate by weight, be prepared from primarily of Radix Ceratostigmatis mini 15 parts, Herba Passiflorae Cupiformis 30 parts, Radix Zanthoxyli Spinifolii 15 parts, Radix Polygoni Runcinati 10 parts, Araliae cardatae 22 parts, Radix Angelicae Pubescentis 10 parts, Rhizoma Drynariae 30 parts, YIKOUXUE 10 parts, Herba hyperici attenuati 60 parts, the Radix Astragali 30 parts, twoflower rattlesnake plantain 25 parts, pittosporm root 15 parts, Rhizoma Zingiberis 55 parts, Radix Lespedezae Buergeri 30 parts, panax japonicus 20 parts, Caulis Akebiae 10 parts, Bulbus Eleutherines Plicatae 25 parts, Radix Fissistigmatis Oldhamii 15 parts and adjuvant.
A preparation method for the medicine of aforesaid expelling wind and removing dampness, gets said medicine, conventionally extracts, and combines with conventional pharmaceutical adjuvants, also can not add adjuvant, make traditional drug formulations.
In the preparation method of the medicine of aforesaid expelling wind and removing dampness, described pharmaceutical preparation is oral formulations.
In the preparation method of the medicine of aforesaid expelling wind and removing dampness, described oral agents comprises oral liquid, pill, tablet, capsule, electuary or medicated wine.
In the preparation method of the medicine of aforesaid expelling wind and removing dampness, the preparation method of described oral liquid is: get said medicine, decoct with water 3 times, first time adds 12 times amount soak by water 3 hours, and second time adds 10 times amount soak by water 2 hours, third time adds 8 times amount soak by water 1 hour, merge decoction liquor, when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, and the sucrose separately getting the amount of making 30% adds in the water boiled to be made to be uniformly dissolved, filter, make simple syrup; Added in extractum for subsequent use by simple syrup, add the sodium benzoate of the amount of making 0.2%, boil dissolving, add pure water and be settled to full dose, stir evenly, filter, embedding, obtains oral liquid.
In the preparation method of the medicine of aforesaid expelling wind and removing dampness, the preparation method of described pill is: get said medicine, decocts with water 3 times, and first time adds 12 times amount soak by water 3 hours, second time adds 10 times amount soak by water 2 hours, third time adds 8 times amount soak by water 1 hour, merges decoction liquor, and when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, extractum mixes general ball with the starch of extractum amount 15%, drying, coating, to obtain final product.
In the preparation method of the medicine of aforesaid expelling wind and removing dampness, the preparation method of described tablet is: get said medicine, decocts with water 3 times, and first time adds 12 times amount soak by water 3 hours, second time adds 10 times amount soak by water 2 hours, third time adds 8 times amount soak by water 1 hour, merges decoction liquor, and when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, extractum mixes with the starch of extractum amount 20%, tabletting, film coating, obtains tablet.
In the preparation method of the medicine of aforesaid expelling wind and removing dampness, the preparation method of described capsule is: get above-mentioned medical material, mixing, with the alcohol reflux 2 times of 6 times amount 70%, each 1 hour, extracting liquid filtering, filtrate recycling ethanol and when being condensed into 50-60 DEG C relative density be the extractum of 1.20-1.25, separately get the starch of extractum amount 30% and the magnesium stearate of 0.7% and extractum to mix, with the alcohol granulation of 60%, dry, pulverize, filled capsules, obtains capsule.
Medicine of the present invention is prepared from primarily of Radix Ceratostigmatis mini, Herba Passiflorae Cupiformis, Radix Zanthoxyli Spinifolii, Radix Polygoni Runcinati, Araliae cardatae, Radix Angelicae Pubescentis, Rhizoma Drynariae, YIKOUXUE, Herba hyperici attenuati, the Radix Astragali, twoflower rattlesnake plantain, pittosporm root, Rhizoma Zingiberis, Radix Lespedezae Buergeri, panax japonicus, Caulis Akebiae, Bulbus Eleutherines Plicatae, Radix Fissistigmatis Oldhamii.Wherein, Radix Ceratostigmatis mini, Classification system Ceratostigma willlmottianum Stapf is the root of the little ceratostigma plumbaginoides Bunge of Plumbaginaceae ceratostigma plumbaginoides Bunge platymiscium, " Yunnan Chinese herbal medicine ": " dredge the meridian passage, wind-damp dispelling.Dispelling the wind and dampness pathogens is numb, vasculitis." usage and function of plant: Herb is used as medicine, have restore menstrual flow and invigorate blood circulation, the effect of expelling wind and removing dampness, dispersing cold for relieving pain, strengthening the spleen to promote digestion, in order to treat the diseases such as traumatic injury, rheumatic arthritis, menoxenia, dyspepsia.Herba Passiflorae Cupiformis, foreign language title Herb of CupleafPassionflower, Passiflora cupiformis Mast., be wound around herbaceous species, reach 6m tendril and leave axil.Sweet in the mouth, micro-puckery, warm in nature, expelling wind and removing dampness; Promoting blood circulation and stopping pain; Tranquilizing by nourishing the heart.Cure mainly rheumatic heart disease; Hematuria; Nebulousurine; Hemiplegia; Furuncle; Traumatic hemorrhage; Eruptive disease abdominal distention pain.Radix Zanthoxyli Spinifolii, Classification system Caesalpinia cucullata Roxb is root or the root bark of dicotyledon medicine rutaceae Zanthoxylum Dimorphophyllum Hemsl. Var Spinifolium Rhed. Et Wils.Rattan is used as medicine, and has the effect of promoting blood circulation and stopping pain.Control cough due to wind and cold, rheumatic numbness, traumatic injury, traumatic hemorrhage, constipation.Radix Polygoni Runcinati, Classification system Polygonum runcinatum Buch.-Ham, for polygonaceae plant lacks the root of the scarce waist leaf knotweed of waist leaf knotweed or China, has effect of heat-clearing and toxic substances removing, relaxing muscles and tendons to promote blood circulation.1. " classify herbal ": " taste is sweet, and property is put down." 2. " Guizhou folk medicine ": " cold in nature, bitter in the mouth is micro-puckery." 3. " the practical Chinese herbal medicine in Guangxi newly selects ": " sour and astringent, flat, nontoxic." enter the heart, liver, kidney channel.Control unconsciousness due to high fever, pulmonary tuberculosis cough, burn, scrofula, carbuncle furuncle and phyma poison, traumatic injury, rheumatic arthralgia, menoxenia.Araliae cardatae is the root welding technology of Araliaceae Aralia cordata Thunb, pubescence Radix Ariliae, Radix Ariliae and dense purple Radix Ariliae.For dry rhizome and the root of Zhi thing Shi Cortex araliae chinensis.Rhizome is thick, and irregular cylinder in flexion torsion, has calmness, hypnosis, analgesia, antiinflammatory action.Radix Angelicae Pubescentis is the dry root of samphire Angelica pubescens Angelicapubescens Maxim.f.biserrata Shan et Yuan.Acrid in the mouth, hardship, slightly warm in nature.There is expelling wind and removing dampness, effect of arthralgia aggravated by cold pain relieving.For anemofrigid-damp arthralgia, wash pain, few cloudy volt wind headache, wind and cold holds wet headache under the arm.Rhizoma Drynariae, Classification system Davallia mariesii Moore ex Bak., has the kidney invigorating bone strengthening, continuous effect of hindering pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.YIKOUXUE is the herb of pigeon-wheat section plant Herba Polytrichi.Be called as only son and heir's grass (" will planted by middle traditional Chinese medicines "), have and search wind, damp eliminating, cold expelling, effect of pain relieving.Be used for the treatment of rheumatic arthritis, rheumatoid arthritis, hemiplegia, contracture of the limbs, sciatica, stomach abdomen cold type of pain, toothache, lymphoid tuberculosis, nerve must dermatitis, topical anesthesia, sprain.Herba hyperici attenuati, Classification system Hypericum attenuatum Choisy, be herbaceos perennial, stem is cylindrical, scattered black gland point or speckle.Single leaf is to life, and Long Circle, top is blunt, and base portion is gradually narrow slightly embraces stem.Medicinal have hemostasis, analgesia, the effects such as lactogenesis.Hemostasis, analgesia, lactogenesis.For spitting of blood, spit blood, metrorrhagia, rheumatic arthritis, neuralgia, traumatic injury, agalactosis, mastitis; Wound hemorrhage is controlled in external, carbuncle furuncle and phyma poison.The Radix Astragali, Classification system, Astragalus membranaceus (Fisch.) Bunge, the pure natural product that the common people often eat, the jingle that folklore " often drinking astragali seu Hedysari Decoction; disease-prevention health health ", mean through the conventional Radix Astragali with the precious Ganoderma of fine jade decoct soup or soaked generation tea-drinking, there is good disease-prevention health effect.The Radix Astragali and Radix Ginseng all belong to QI invigorating good medicine, and Radix Ginseng biases toward strongly invigorating primordial QI, recuperating depleted YANG and rescuing the patient from collapse, and be usually used in the emergency cases such as collapse, shock, effect is better.The Radix Astragali then based on tonify deficiency, be usually used in asthenia with the passing of time, low, the thready pulse without strength person of speech.Some people is easy to catch cold once meeting Changes in weather, and the traditional Chinese medical science is called " table is not solid ", and can carry out consolidating superficial resistance with the Radix Astragali, the informal dress Radix Astragali can avoid regular flu.The Radix Astragali has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contraction, regulate blood sugar content.The Radix Astragali can not only coronary artery dilator, improves blood supply of cardiac muscle, improves immunologic function, and can the process of delaying cell aging.Radix Astragali instant, can decoct soup, soft extracts, infusing drugs in wine, enter dish etc.Twoflower rattlesnake plantain is used for relaxing muscles and tendons to promote blood circulation, invigorating the spleen and replenishing QI, mends waist kidney.Cure mainly traumatic injury, lumbago due to renal deficiency, dizziness and tinnitus, orchitis.Twoflower rattlesnake plantain, medicinal source is beautiful phoenix flower Habenaria dentata (Swartz) Schlecht. (Habenaria miersiana Champ.) of the orchid family beautiful phoenix flower plant Pluma Anseris domestica, and for relaxing muscles and tendons to promote blood circulation, invigorating the spleen and replenishing QI, mends waist kidney.Cure mainly traumatic injury, lumbago due to renal deficiency, dizziness and tinnitus, there is tonifying the lung kidney, effect of diuresis.Pittosporm root, Classification system Pittosporum glabratum Lindl. is evergreen shrubs, bitter, tepor.Promoting blood circulation to remove obstruction in the collateral, synthetism is subsided a swelling, removing toxic substances pain relieving.For rheumatic arthritis, sciatica, fracture, stomachache, toothache, hypertension, neurasthenia, emission, cough, limbs fatigue, hematuria.Rhizoma Zingiberis is the dry rhizome of zingiber Zingiber oj-jicinale Rosc..Winter excavates, and removing fibrous root and silt, dry or cold drying.Take advantage of fresh slices to dry or cold drying person is called " dried ginger slice ".Have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, effect of warming the lung to resolve fluid-retention.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, cold fluid-retention is breathed with cough.Radix Lespedezae Buergeri is the dry root of leguminous plant Indigofera stachyoides Lindl. Indigofera stachyoides Lindl., and the whole year all can excavate, and removing silt, dries.This product is also Minority Nationalities in Guizhou medication.Pungent micro-hardship, temperature.Have and induce sweat, reduce phlegm, dampness removing, invigorate blood circulation.Be used for the treatment of the cough due to common cold, fever with aversion to cold, head-body-pain, infantile convulsion, ascarid is suffered from abdominal pain, married woman's abdominal pain due to blood stasis.Panax japonicus is the dry rhizome of Araliaceae Rhizoma Panacis Japonici Panaxjaponicus C.A.Mey., and it is the one of China's Chinese crude drug, can clearing away summer-heat; Secretion replenishing and throat moistening.There is summer-heat impairment of body fluid; Dry mouth and tougue; Vexed god is tired; Pharyngalgia hoarseness; Toothache caused by fire of deficiency type; Alopecia; Strengthening by means of tonics, eliminating stasis to stop pain, effect of eliminating the phlegm of stopping blooding.For weak after being ill, chronic cough is spat blood, cough with copious phlegm, injury from falling down.Caulis Akebiae is plants of Lardizabalaceae, has inducing diuresis for treating stranguria syndrome, and clear away heart-fire relieving restlessness, the effect of stimulating milk secretion of stimulating the menstrual flow, and for stranguria, edema, vexed dark coloured urine, aphtha of the mouth and tongue, amenorrhea breast is few, damp and hot arthralgia pain.Bulbus Eleutherines Plicatae belongs to herbaceous plant.Leaf mostly is wide lanceolar or wide bar shaped, and umbellate cyme is born in the top of scape, has heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, and effect of hemostasis, is used for the treatment of rheumatic arthralgia, treating swelling and pain by traumatic injury, epistaxis, rhinitis etc.Radix Fissistigmatis Oldhamii is the root of annonaceae plant Radix Fissistigmatis Oldhamii, can expelling wind and removing dampness, promoting blood circulation and stopping pain, cures mainly rheumatic arthralgia, lumbago, stomachache, traumatic injury etc.
Compared with prior art, the present invention adopts above-mentioned raw materials to make medicine, and each component raw material has good synergistic function, plays altogether to have to regulate QI and blood, Yin Yang balancing, cold-dispelling, except arthralgia chiefly caused by damp pathogen and remarkable lenitive effect.Be used for the treatment of cervical spondylosis, lumbar spondylosis, hyperosteogeny, rheumatic arthritis, rheumatoid, scapulohumeral periarthritis, gout, puerperal fever and traumatic injury; And evident in efficacy, side effect is little, reaches the object of invention.
Applicant carried out following experiments, provable the present invention has effective effect;
Experimental example expelling wind and removing dampness the effects
1 clinical data
1.1 case selections, with reference to Americanism damp disease association RA diagnostic criterias in 1987, allly to meet in following 75: stiff every day in (1) morning continues at least 1h, the course of disease >=6 week; (2) arthralgia number >=3; (3) symmetrical swelling >=6 week; (4) Rheumatoid factors (RF) positive (dripping number >1:20); (5) ESR, >30mm/h; (6) rheumatic subcutaneous nodule is had; (7) sheet taken the photograph by affected joints x line is that RA changes (having the narrow of the sparse and joint space of matter at least), and namely elects observation case as inactive medicine more than 1 person improving the state of an illness.
1.2 physical data examine case totally 104 examples, and 104 routine rheumatoid arthritis people are divided into two groups at random: medicine group of the present invention is treatment group 54 example, matched group 50 example.Man 20 example in treatment group, female 34 example, at 18 ~ 62 years old age, average 40 years old, the course of disease is person 27 example within 1 year, 2-4 person 17 example, and 4 years with person 10 example; In matched group, man 19 example, female 31 example, age 17-62 year, average 37.4 years old, course of disease person 28 example within 1 year, 2-4 years persons 14 example, more than 4 years person 8 examples.Between two groups, there is comparability.
2 Therapeutic Method
2.1 treatment groups are treated with medicine of the present invention (being prepared according to the method for embodiment 1), each oral 10g, every day 3 times.
2.2 matched group ibuprofen, each 300m, every day 3 times, takes in meal.
Two groups of courses for the treatment of are 6 weeks, treatments period no longer uses other medicines, observe the pain of affected joints, swelling and moving obstacle, by heavy, medium and light, be difficult 3,2,1,0 and score, and record untoward reaction, before and after treatment, all detect the stiff time in morning, hand-grip strength, sheet contrast taken the photograph by ESR, RF, both hands foot normotopia x line.
3 therapeutic outcomes
3.1 criterions of therapeutical effect are cured in the recent period: morning stiff <15rain, arthralgia and swelling disappear, and moving obstacle and hand-grip strength return to normal, and ESR is normal, and RF is negative; Effective: morning stiff <30rain, affected joints 3 disease is always scored decline >80%; Effective: patient's self evaluation is improved, affected joints is always scored decline >40%; Invalid: affected joints is always scored decline <40%, before and after treatment, symptom is unchanged.
3.2 therapeutic outcome
3.2.1 two groups of comparitive study treatment groups cure 24 examples (44.44%) in the recent period, effective 2l example (38.89%); Effective 7 examples (12.96%); Invalid 2 examples (3.7%); Total effective rate is 96.30%.Matched group cures 13 examples (26%) in the recent period; Effective 17 examples (34%); Effective 11 examples (22%); No effect 9 (18%); Total effective rate is 82%.
3.2.2 score before and after two groups of affected joints treatments and compare in table 1, table 2 and table 3.
Before and after table 1 liang group affected joints treatment, arthralgia is scored and is compared (x ± s)
* P<0.05 is compared with before treatment;
Before and after table 2 liang group affected joints treatment, arthroncus is scored and is compared (x ± s)
* P<0.05 is compared with before treatment;
Before and after table 3 liang group affected joints treatment, joint movement disorder is scored and is compared (x ± s)
* P<0.05 is compared with before treatment;
Conclusion: the present invention has expelling wind and removing dampness, lenitive effect.
Below in conjunction with embodiment, invention is further described, but not as the foundation limited the present invention.
Detailed description of the invention:
Embodiment 1:
Formula: Radix Ceratostigmatis mini 15g, Herba Passiflorae Cupiformis 30g, Radix Zanthoxyli Spinifolii 15g, Radix Polygoni Runcinati 10g, Araliae cardatae 22g, Radix Angelicae Pubescentis 10g, Rhizoma Drynariae 30g, YIKOUXUE 10g, Herba hyperici attenuati 60g, Radix Astragali 30g, twoflower rattlesnake plantain 25g, pittosporm root 15g, Rhizoma Zingiberis 55g, Radix Lespedezae Buergeri 30g, panax japonicus 20g, Caulis Akebiae 10g, Bulbus Eleutherines Plicatae 25g and Radix Fissistigmatis Oldhamii 15g.
Technique: get said medicine, decoct with water 3 times, first time adds 12 times amount soak by water 3 hours, second time adds 10 times amount soak by water 2 hours, and third time adds 8 times amount soak by water 1 hour, merges decoction liquor, when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, the sucrose separately getting the amount of making 30% adds in the water boiled to be made to be uniformly dissolved, and filters, makes simple syrup; Added in extractum for subsequent use by simple syrup, add the sodium benzoate of the amount of making 0.2%, boil dissolving, add pure water and be settled to full dose, stir evenly, filter, embedding, obtains oral liquid.
Specification: every bottle of 10ml.
Usage and dosage a: 10ml, every day 3 times, oral.
Embodiment 2:
Formula: Radix Ceratostigmatis mini 30g, Herba Passiflorae Cupiformis 10g, Radix Zanthoxyli Spinifolii 30g, Radix Polygoni Runcinati 15g, Araliae cardatae 40g, Radix Angelicae Pubescentis 15g, Rhizoma Drynariae 50g, YIKOUXUE 15g, Herba hyperici attenuati 90g, Radix Astragali 50g, twoflower rattlesnake plantain 40g, pittosporm root g, Rhizoma Zingiberis 90g, Radix Lespedezae Buergeri 50g, panax japonicus 30g, Caulis Akebiae 15g, Bulbus Eleutherines Plicatae 40g and Radix Fissistigmatis Oldhamii 25g.
Technique: get said medicine, decoct with water 3 times, first time adds 12 times amount soak by water 3 hours, and second time adds 10 times amount soak by water 2 hours, and third time adds 8 times amount soak by water 1 hour, merge decoction liquor, when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, and extractum mixes general ball with the starch of extractum amount 15%, dry, coating, obtains pill.
Specification: every ball 0.5g.
Usage and dosage: every day 3 times, each 2, oral.
Embodiment 3:
Formula: Radix Ceratostigmatis mini 5g, Herba Passiflorae Cupiformis 10g, Radix Zanthoxyli Spinifolii 5g, Radix Polygoni Runcinati 5g, Araliae cardatae 5g, Radix Angelicae Pubescentis 5g, Rhizoma Drynariae 10g, YIKOUXUE 5g, Herba hyperici attenuati 30g, Radix Astragali 10g, twoflower rattlesnake plantain 10g, pittosporm root 5g, Rhizoma Zingiberis 20g, Radix Lespedezae Buergeri 10g, panax japonicus 10g, Caulis Akebiae 5g, Bulbus Eleutherines Plicatae 10g and Radix Fissistigmatis Oldhamii 5g.
Technique: get said medicine, decoct with water 3 times, first time adds 12 times amount soak by water 3 hours, and second time adds 10 times amount soak by water 2 hours, and third time adds 8 times amount soak by water 1 hour, merge decoction liquor, when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, and extractum mixes with the starch of extractum amount 20%, tabletting, film coating, obtains tablet.
Specification: every sheet 0.5g.
Usage and dosage: every day 3 times, each 2, oral.
Embodiment 4:
Formula: Radix Ceratostigmatis mini 25g, Herba Passiflorae Cupiformis 45g, Radix Zanthoxyli Spinifolii 25g, Radix Polygoni Runcinati 10g, Araliae cardatae 35g, Radix Angelicae Pubescentis 10g, Rhizoma Drynariae 45g, YIKOUXUE 10g, Herba hyperici attenuati 85g, Radix Astragali 45g, twoflower rattlesnake plantain 35g, pittosporm root 25g, Rhizoma Zingiberis 85g, Radix Lespedezae Buergeri 45g, panax japonicus 25g, Caulis Akebiae 10g, Bulbus Eleutherines Plicatae 35g and Radix Fissistigmatis Oldhamii 20g.
Technique: get above-mentioned medical material, mixing, with the alcohol reflux 2 times of 6 times amount 70%, each 1 hour, extracting liquid filtering, filtrate recycling ethanol and when being condensed into 50-60 DEG C relative density be the extractum of 1.20-1.25, separately get the starch of extractum amount 30% and the magnesium stearate of 0.7% and extractum and mix, with the alcohol granulation of 60%, dry, pulverize, filled capsules, obtains capsule.
Specification: every 0.5g.
Usage and dosage: every day 3 times, each 2, oral.
Claims (10)
1. the medicine of an expelling wind and removing dampness, it is characterized in that, calculate by weight, be prepared from primarily of Radix Ceratostigmatis mini 1-50 part, Herba Passiflorae Cupiformis 5-80 part, Radix Zanthoxyli Spinifolii 1-60 part, Radix Polygoni Runcinati 1-40 part, Araliae cardatae 1-70 part, Radix Angelicae Pubescentis 1-40 part, Rhizoma Drynariae 5-80 part, YIKOUXUE 1-40 part, Herba hyperici attenuati 10-110 part, Radix Astragali 1-70 part, twoflower rattlesnake plantain 1-60 part, pittosporm root 1-60 part, Rhizoma Zingiberis 1-110 part, Radix Lespedezae Buergeri 1-70 part, panax japonicus 1-50 part, Caulis Akebiae 1-40 part, Bulbus Eleutherines Plicatae 1-70 part, Radix Fissistigmatis Oldhamii 1-60 and adjuvant.
2. the medicine of expelling wind and removing dampness as claimed in claim 1, it is characterized in that, calculate by weight, be prepared from primarily of Radix Ceratostigmatis mini 5-30 part, Herba Passiflorae Cupiformis 10-50 part, Radix Zanthoxyli Spinifolii 5-30 part, Radix Polygoni Runcinati 5-15 part, Araliae cardatae 5-40 part, Radix Angelicae Pubescentis 5-15 part, Rhizoma Drynariae 10-50 part, YIKOUXUE 5-15 part, Herba hyperici attenuati 30-90 part, Radix Astragali 10-50 part, twoflower rattlesnake plantain 10-40 part, pittosporm root 5-30 part, Rhizoma Zingiberis 20-90 part, Radix Lespedezae Buergeri 10-50 part, panax japonicus 10-30 part, Caulis Akebiae 5-15 part, Bulbus Eleutherines Plicatae 10-40 part, Radix Fissistigmatis Oldhamii 5-25 and adjuvant.
3. the medicine of expelling wind and removing dampness as claimed in claim 2, it is characterized in that, calculate by weight, be prepared from primarily of Radix Ceratostigmatis mini 15 parts, Herba Passiflorae Cupiformis 30 parts, Radix Zanthoxyli Spinifolii 15 parts, Radix Polygoni Runcinati 10 parts, Araliae cardatae 22 parts, Radix Angelicae Pubescentis 10 parts, Rhizoma Drynariae 30 parts, YIKOUXUE 10 parts, Herba hyperici attenuati 60 parts, the Radix Astragali 30 parts, twoflower rattlesnake plantain 25 parts, pittosporm root 15 parts, Rhizoma Zingiberis 55 parts, Radix Lespedezae Buergeri 30 parts, panax japonicus 20 parts, Caulis Akebiae 10 parts, Bulbus Eleutherines Plicatae 25 parts, Radix Fissistigmatis Oldhamii 15 parts and adjuvant.
4. a preparation method for the medicine of the expelling wind and removing dampness as described in claim 1-3, is characterized in that: get said medicine, conventionally extracts, and combines with conventional pharmaceutical adjuvants, also can not add adjuvant, make traditional drug formulations.
5. the preparation method of the medicine of expelling wind and removing dampness as claimed in claim 4, is characterized in that: described pharmaceutical preparation is oral formulations.
6. the preparation method of the medicine of expelling wind and removing dampness as claimed in claim 5, is characterized in that: described oral agents comprises oral liquid, pill, tablet, capsule, electuary or medicated wine.
7. the preparation method of the medicine of expelling wind and removing dampness as claimed in claim 6, it is characterized in that: the preparation method of described oral liquid is: get said medicine, decoct with water 3 times, first time adds 12 times amount soak by water 3 hours, and second time adds 10 times amount soak by water 2 hours, third time adds 8 times amount soak by water 1 hour, merge decoction liquor, when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, and the sucrose separately getting the amount of making 30% adds in the water boiled to be made to be uniformly dissolved, filter, make simple syrup; Added in extractum for subsequent use by simple syrup, add the sodium benzoate of the amount of making 0.2%, boil dissolving, add pure water and be settled to full dose, stir evenly, filter, embedding, obtains oral liquid.
8. the preparation method of the medicine of expelling wind and removing dampness as claimed in claim 6, it is characterized in that: the preparation method of described pill is: get said medicine, decocts with water 3 times, first time adds 12 times amount soak by water 3 hours, second time adds 10 times amount soak by water 2 hours, third time adds 8 times amount soak by water 1 hour, merges decoction liquor, and when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, extractum mixes general ball with the starch of extractum amount 15%, drying, coating, to obtain final product.
9. the preparation method of the medicine of expelling wind and removing dampness as claimed in claim 6, it is characterized in that: the preparation method of described tablet is: get said medicine, decocts with water 3 times, first time adds 12 times amount soak by water 3 hours, second time adds 10 times amount soak by water 2 hours, third time adds 8 times amount soak by water 1 hour, merges decoction liquor, and when being condensed into 50-60 DEG C, relative density is the extractum of 1.15-1.20, extractum mixes with the starch of extractum amount 20%, tabletting, film coating, obtains tablet.
10. the preparation method of the medicine of expelling wind and removing dampness as claimed in claim 5, is characterized in that: the preparation method of described capsule is: get above-mentioned medical material, mixing, with the alcohol reflux 2 times of 6 times amount 70%, each 1 hour, extracting liquid filtering, filtrate recycling ethanol and when being condensed into 50-60 DEG C relative density be the extractum of 1.20-1.25, separately get the starch of extractum amount 30% and the magnesium stearate of 0.7% and extractum to mix, with the alcohol granulation of 60%, dry, pulverize, filled capsules, obtains capsule.
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