CN106237290A - A kind of Chinese medicine decoction for treating ankylosing spondylitis - Google Patents

A kind of Chinese medicine decoction for treating ankylosing spondylitis Download PDF

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CN106237290A
CN106237290A CN201610764996.2A CN201610764996A CN106237290A CN 106237290 A CN106237290 A CN 106237290A CN 201610764996 A CN201610764996 A CN 201610764996A CN 106237290 A CN106237290 A CN 106237290A
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parts
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herba
ankylosing spondylitis
folium
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虞志秋
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Abstract

The invention discloses a kind of Chinese medicine decoction for treating ankylosing spondylitis, the Chinese crude drug of following weight proportion be prepared from: Radix Achyranthis Bidentatae 8 parts, Dalbergia odorifera 9 parts, poison creeper 10 parts, Ramulus Cinnamomi 11 parts, 11 parts of Herba Ephedrae, Rhizoma Zingiberis 4 parts, Herba Taxilli 8 parts, Radix Stephaniae Tetrandrae 7 parts, Caulis Lonicerae 6 parts, Herba Murdanniae Divergentis 12 parts, Rhizoma Alismatis 9 parts, 8 parts of Radix Glycyrrhizae, inferior 10 parts of corruption, 6 parts of black Mulberry, the Cortex Eucommiae 5 parts, Folium Alstoniae Scholaris 6 parts, real 12 parts of Ramulus et Folium Tamaricis, Folium Ilicis Purpureae 5 parts, largespike woodnettle root 5 parts, branch of the willow 6 parts, Semen allii fistulosi 5 parts, Fructus Corni 4 parts, river mouth lotus throne Herba pteridii latiusculi 5 parts, pittosporm root 4 parts.Clinical trial certificate, the present invention reasonable compatibility by Chinese crude drug, contribute to treating ankylosing spondylitis, and can effectively prevent recurrence, reach integrally-regulated and long-term effect good effects.

Description

A kind of Chinese medicine decoction for treating ankylosing spondylitis
Technical field
The present invention relates to a kind of Chinese medicine decoction, be specifically related to a kind of Chinese medicine decoction for treating ankylosing spondylitis.
Background technology
Ankylosing spondylitis is one of world medicine difficult problem, with male adults morbidity for many.This disease mainly involves bones of the body bone Joint and spinal column attachment point, it is possible to involving the big joint of extremity, early clinical manifestation is not true to type, may occur in which low grade fever, weak, become thin Symptom, causes many patients by mistaken diagnosis or to miss therapic opportunity, and middle and advanced stage then may result in stiff tetanic, the joint distortion change of spinal column Shape, makes patient lose basic somatic function, and patient brings serious misery, brings great bearing to its family or even society Load.Doctor trained in Western medicine its pathogenesis the clearest and the most definite to primary disease at present, treatment is still a stubborn problem.Conventional treatment by Chinese herbs, Only rely on several taste medicine to be difficult to look after comprehensively, multi-medicament suitably must be coordinated, improve curative effect or reduce untoward reaction, to adapt to The treatment of the complicated state of an illness.In view of the various active composition interaction in vivo of various Chinese crude drugs is sufficiently complex, various medicines The change of the aspects such as pharmacokinetics in vivo and pharmacodynamics can produce various impacts, medicine to the interaction between medicine During combination, both may produce Synergistic drug effect, it is also possible to produce antagonism, and then cause Drug therapy declines or Endodontic failure, some drug combination also can make drug toxicity strengthen, cause untoward reaction;Even if drug combination makes effect increase By force, but the tolerant ability of body can be exceeded when therapeutical effect excessively strengthens, it is possible to cause untoward reaction, or even harm suffered from Person.Part research to treatment ankylosing spondylitis, the most easily problem appear to is that the compatibility of medicines in a prescription not toward plan Chinese medicinal formulae certainly Rationally, may often be such that only to cure mainly from some single or polypharmaceutic discrete function and go to copy mechanically and apply indiscriminately Chinese medicine with some pharmacodynamic index Theory, prescription flavour of a drug are arbitrarily added and subtracted, and cause prescription unreasonable, contradict with Chinese medical theory.
Summary of the invention
It is desirable to provide a kind of Chinese medicine decoction for treating ankylosing spondylitis, by the Reasonable of Chinese crude drug 5, contribute to treating ankylosing spondylitis, and can effectively prevent recurrence, reach integrally-regulated and long-term effect good effects.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine decoction for treating ankylosing spondylitis, is prepared from by the Chinese crude drug of following weight proportion: Radix Achyranthis Bidentatae 8 Part, Dalbergia odorifera 9 parts, poison creeper 10 parts, Ramulus Cinnamomi 11 parts, 11 parts of Herba Ephedrae, Rhizoma Zingiberis 4 parts, Herba Taxilli 8 parts, Radix Stephaniae Tetrandrae 7 parts, Caulis Lonicerae 6 Part, Herba Murdanniae Divergentis 12 parts, Rhizoma Alismatis 9 parts, 8 parts of Radix Glycyrrhizae, inferior 10 parts of corruption, 6 parts of black Mulberry, the Cortex Eucommiae 5 parts, Folium Alstoniae Scholaris 6 parts, Ramulus et Folium Tamaricis 12 parts in fact, Folium Ilicis Purpureae 5 parts, largespike woodnettle root 5 parts, branch of the willow 6 parts, Semen allii fistulosi 5 parts, Fructus Corni 4 parts, river mouth lotus throne Herba pteridii latiusculi 5 parts, pittosporm root 4 parts.
Preparation method is: above-mentioned pulverizing medicinal materials is become coarse powder;Decoct twice, decoct 8 times amount that add water for the first time, soak 2h, Decoct 3h, filter;Second time decocts 6 times amount that add water, and decocts 2h, filters;Merge subpackage after twice decocting liquid mix homogeneously.
Further, above-mentioned Chinese medicine decoction purposes in preparation treatment or prevention ankylosing spondylitis medicine.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
The dry root of Radix Achyranthis Bidentatae [source] amaranthaceous plant Radix Achyranthis Bidentatae.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards. For soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.
Dalbergia odorifera [source] is the root of leguminous plant Lignum Dalbergiae Odoriferae wingceltis, stem's heartwood.[nature and flavor] mildly bitter flavor, gas is fragrant, warm in nature.Enter Wind, Tu Ta.[function cures mainly] Qinghuo Jiedu, regulating QI to relieve pain, stopping nausea and vomiting by lowering the adverse flow of QI.Cure mainly heating, laryngopharynx swelling and pain, Light-headedness, gastral cavilty Bitterly, alimentary toxicosis, nausea and vomiting.
Poison creeper [source] is Herb or the root of Anacardiaceae plant poison creeper.[nature and flavor] bitter in the mouth, micro-acid.Warm in nature.[function cures mainly] Heat-clearing and toxic substances removing, cough-relieving, reducing swelling and alleviating pain, except wind is antipruritic.Cure mainly cough, rheumatic fever arthromyodynia, limbs joint red and swollen heat pain, bend and stretch not Profit, lumbago, Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) allergy.
Ramulus Cinnamomi [source] this product is the dry twig of canella Cortex Cinnamomi.[nature and flavor] acrid, sweet, warm.[return through] GUIXIN, Lung, bladder warp.[function cures mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, gastral cavity abdomen is cold Bitterly, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Herba Ephedrae [source] this product is the dry herb stem of Ephedraceae plant plait Herba Ephedrae.[nature and flavor] hardship pungent, micro-, temperature.[return Warp] return lung, bladder warp.[function cures mainly] diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chest breath with cough, Edema due to wind pathogen edema;Bronchial asthma.
Rhizoma Zingiberis [source] this product is the dry rhizome of zingiber.[nature and flavor] are pungent, hot.[return through] return spleen, stomach, kidney, the heart, Lung meridian.[function cures mainly] Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG promotes blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, cold extremities faint pulse, Phlegm retention is breathed with cough.
Herba Taxilli [source] this product is the dry stem and branch with leaf of Loranthaceae plant Herba Taxilli.[nature and flavor] bitter, sweet, flat. [return through] returns liver, kidney channel.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.For rheumatic arthralgia, the acid of waist knee joint Soft, muscles and bones is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement;Hypertension.
Radix Stephaniae Tetrandrae [source] this product is the dry root of menispermaceous plants Radix stephaniae tetrandrae.[nature and flavor] are bitter, cold.[return through] returns bladder, lung Warp.[function cures mainly] inducing diuresis to remove edema, wind-expelling pain-stopping.For edema tinea pedis, dysuria, eczema sore, rheumatic arthralgia;High blood Pressure.
Caulis Lonicerae [source] this product is the dry stem branch of caprifoliaceae plant Radix Ophiopogonis.[function cures mainly] heat-clearing and toxic substances removing, dispelling wind Dredging collateral.Generate heat for epidemic febrile disease, toxic-heat and blood stasis, carbuncle skin infection, beriberoid pyretic arthralgia, redness and swelling of joints burning pain.
Herba Murdanniae Divergentis [source] medical material Ji Yuan: for root or the Herb of Commelianaceae plant purple back of the body Herba Pyrolae.[nature and flavor] are sweet;Micro- Bitter;Flat.[function cures mainly] clearing away lung-heat to relieve cough;Invigorating the lung and the kidney;Regulating menstruation, hemostasis.Main cough due to lung-heat;The deficiency of vital energy is breathed with cough;Dizziness and tinnitus;Fracture; Spit blood.
The dry tuber of Rhizoma Alismatis [source] Notes On Alism At Aceae Rhizoma Alismatis.[nature and flavor] are sweet, cold.[return through] returns kidney, bladder warp.[merit Can cure mainly] diuresis, clearing away damp-heat.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, Stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, tired Idle weak, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
The rotten inferior platymiscium corruption of rotten inferior [source] Verenaceae is inferior, is used as medicine with root and leaf.The four seasons can adopt, using fresh herb or dry. [nature and flavor] are bitter, puckery, cold.[function cures mainly] heat-clearing and toxic substances removing, reducing swelling and alleviating pain, astringing to arrest bleeding.For dysentery, appendicitis, Radix Tripterygii Wilfordii Poisoning;Burn and scald, lymphadenitis, carbuncle furuncle, venom, traumatic hemorrhage are controlled in external.
Radix Tripterygii Wilfordii [source] Celastraceae tripterygium plant Radix Tripterygii Wilfordii, is used as medicine with root, leaf, flower and fruit.[nature and flavor] are bitter, pungent, Cool.Very toxic.[function cures mainly] dispels the wind, removing toxic substances, parasite killing.External treating rheumatic arthritis, skin is itched, and kills maggot, wriggler, goes out Oncomelania, poison Mus.
Black Mulberry [source] is black or the erythrocarpus of the black Mulberry of moraceae plants.[nature and flavor] sour in the mouth is micro-sweet.[function cures mainly] adjusts Joint abnormal blood matter and bile matter, the pharyngolaryngitis that disappears swells, stops hot body fluid to flee in upper respiratory tract, and quench the thirst increasing food, except infections heals Skin ulcer, clearing away heat to stop diarrhea.Cure mainly hot or blood matter and bile matter disease, as pharyngolaryngitis swells, thirsty poor appetite, oral ulcer, intestinal Road skin ulcer wound, hot diarrhoea and dysentery.
The dry bark of the Cortex Eucommiae [source] the Eucommiaceae plant Cortex Eucommiae.[nature and flavor] are sweet, temperature.[return through] returns liver, kidney channel.[merit Can cure mainly] invigorating the liver and kidney, bone and muscle strengthening, antiabortive.
The dry lobule of Cassia siamea leaf [source] leguminosae cassia plant Cassia siamea.[nature and flavor] bitter in the mouth, cold in nature, enter water, wind Tower.[function cures mainly] expelling wind and removing dampness, reducing swelling and alleviating pain, killing parasites for relieving itching.
The dry leaves of Folium Alstoniae Scholaris [source] Apocynaceae Alstonia plant sugar gum.[nature and flavor] bitter in the mouth, micro-puckery, Cold.[function cures mainly] Qinghuo Jiedu, reducing swelling and alleviating pain, relieving cough and resolving phlegm.
Real [source] Tamaricaceae Ramulus et Folium Tamaricis of Ramulus et Folium Tamaricis or belong to the fruit of multiple Ramulus et Folium Tamaricis together.[nature and flavor] two grades are dry cold, acrid in the mouth. [function cures mainly] is raw dry cold, clearing away heat to stop bleeding, eliminating inflammation and expelling toxin, relieving cough and resolving phlegm, the strong flesh of dampness, softening hardness and disperse swelling, dispelling wind for relieving itching.Cure mainly wet Hot or blood matter disease, hot hemorrhage, pneumonia, flu, cough, moist proctoptosis, diarrhoea, liver is the most swollen, spleen enlargement, wet Rash, skin pruritus etc..
Folium Ilicis Purpureae [source] is the blade of holly plant Ilicis Purpureae.[nature and flavor] are pained, cold.[function cures mainly] controls scald, The long disunion of ulcer, thromboangiitis obliterans, acute and chronic bronchitis, pneumonia, urinary tract infection, bacillary dysentery, traumatic hemorrhage, freezes chilblain, chap Split.
Largespike woodnettle root [source] is the root of contrayerva bulbil Chinese mugwort fiber crops.[nature and flavor] acrid in the mouth, peppery, property heat.[function cures mainly] dispels Wind dehumidifies, blood circulation promoting and blood stasis dispelling.Curing mainly rheumatic arthralgia, numb limbs and tense tendons, tumbling down damages, fracture pain, menoxenia.
Branch of the willow [source] is the flower of Salicaceous Plants Salix babylonica L., branch or root bark.[nature and flavor] bitter in the mouth, property is cold.[function master Control] expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling, pain relieving.Curing mainly rheumatic arthralgia, stranguria with turbid discharge, infectious hepatitis, jaundice, rubella convulsion itches, furuncle Skin ulcer, erysipelas, dental caries, swelling around the eyes.
Semen allii fistulosi [source] is the seed of Bulbus Lilii kind plant Herba Alii fistulosi.[nature and flavor] are pungent, temperature.[function cures mainly] the kidney warming, improving eyesight.Control sun Flaccidity, dizzy.
Fructus Corni [source] this product is the drying and ripening sarcocarp of Cornaceae plant Fructus Corni.[nature and flavor] are sour, puckery, tepor. [return through] returns liver, kidney channel.[function cures mainly] liver and kidney tonifying, essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, lose Urinating frequently, bleeding not during menses, profuse sweating is collapsed.Interior-heat is quenched one's thirst.
River mouth lotus throne Herba pteridii latiusculi [source] medical material Ji Yuan: for the rhizome of Angiopteridaceae plant Angiopteris hokouensis Ching..[nature and flavor] taste Micro-hardship;Puckery;Cool in nature.[function cures mainly] heat-clearing and toxic substances removing;Dispersing swelling and dissipating binds.Main mumps;Scrofula;Carbuncle furuncle;Fracture;Venom.
Pittosporm root [source] is the root of Pittosporaceae plant sea gold, root bark.[nature and flavor] bitter in the mouth, peppery, property is cold.[function master Control] calm.Calm the nerves, qi-restoratives, blood pressure lowering.Cure mainly neurasthenia.Insomnia and dreamful sleep, the seminal emission of body void, hypertension.
Cortex Zingiberis [source] is the rhizome crust of the rhizome of zingiber.[nature and flavor] acrid in the mouth;Cool in nature.[function cures mainly] row water Detumescence.Edema is from the beginning of, dysuria.
The present invention compared with prior art, has the advantages that
1, the selected medicament composing prescription of the present invention, its drug component through dialectical compatibility, complements each other using, has synergism, Infection, anti-inflammatory and antalgic, regulation immunologic function, improve the effect such as hemorheological property and microcirculation, reach relief of symptoms, stop disease The purpose of feelings progress.Prescription is particular about monarch, four natures and five flavors of drug lifting, and waiting is monarch drug altogether, plays leading work in compound recipe With, treat disease by acting on major target class;Deng for ministerial drug, strengthen monarch by acting on the target spot identical with monarch drug The pharmacological action of medicine, thus reduce monarch drug required dosage;Remaining is assistant, makes medical herbs, to improve the bioavailability of monarch, ministerial drug, Coordinate the activity of their each composition.Ramulus Cinnamomi, Herba Ephedrae, largespike woodnettle root three medicine share, evil in exterior cold to dispel outward, inside lead at inner cold coagulation, Spine loses the deficiency supported, especially it is noted that after the Cassia siamea leaf that is especially added with of the present invention and Folium Alstoniae Scholaris compatibility, act on The different target spots of body, synergism can produce the special effect improving human immunologic function, can effectively regulate each internal organs of body Function, improves body and resists the ability of external toxin puzzlement, the generation of complication prevention and prevent old complaint from recurring.
2, the present invention is directed to ankylosing spondylitis mechanism, launch treatment from Mutiple Targets, too many levels, multipath, facing Bed practice in have rapid-action, determined curative effect, patient compliance are good, safe without toxic side effect, patient self can be significantly improved and exempt from Epidemic disease power, treating both the principal and secondary aspects of a disease prevents recurrence, thus has wide potential applicability in clinical practice.
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Weigh: Radix Achyranthis Bidentatae 8 grams, Dalbergia odorifera 9 grams, poison creeper 10 grams, Ramulus Cinnamomi 11 grams, 11 grams of Herba Ephedrae, Rhizoma Zingiberis 4 grams, Herba Taxilli 8 grams, anti- Oneself 7 grams, Caulis Lonicerae 6 grams, Herba Murdanniae Divergentis 12 grams, Rhizoma Alismatis 9 grams, 8 grams of Radix Glycyrrhizae, rotten inferior 10 grams, 6 grams of black Mulberry, the Cortex Eucommiae 5 grams, Folium Alstoniae Scholaris 6 Gram, real 12 grams of Ramulus et Folium Tamaricis, Folium Ilicis Purpureae 5 grams, largespike woodnettle root 5 grams, branch of the willow 6 grams, Semen allii fistulosi 5 grams, Fructus Corni 4 grams, river mouth lotus throne Herba pteridii latiusculi 5 grams, Pittosporm root 4 grams.
Preparation method is: above-mentioned pulverizing medicinal materials is become coarse powder;Decoct twice, decoct 8 times amount that add water for the first time, soak 2h, Decoct 3h, filter;Second time decocts 6 times amount that add water, and decocts 2h, filters;Merge subpackage after twice decocting liquid mix homogeneously.
Usage and dosage: oral, every day 2 times, the most each 1 time, each 100ml;Within 15 days, it is 1 course for the treatment of, takes 2 treatments continuously Journey.
Clinical data:
1, case selection:
Selecting the patients with ankylosing spondylitis 30 example clinical observation in my institute's diagnosis and treatment, clinical symptoms all meets ankylosing spondylitis and examines Take stopgap measures standard.Patient is randomly divided into treatment group and matched group two groups, treatment group 20 example, matched group 10 example.Treatment group and matched group two The group course of disease of case, degrees of symptoms are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes the Chinese medicine decoction obtained by the embodiment of the present invention 1, oral, every day 2 times, the most each 1 time, each 100ml; It within 15 days, it is 1 course for the treatment of.
Matched group is administered orally leflunomide tablet and Radix Paeoniae Alba total glucosides decoction, and the course for the treatment of is with treatment group.
2 courses for the treatment of are treated in smelting continuously, contrast two groups of curative effects.
3, efficacy determination:
(1) curing: clinical symptom disappearance, neck lumbar vertebra can be freely movable, and the sense of swelling and ache in joint disappears.
(2) take a turn for the better: the clinical symptom reliefs such as clinical symptoms has been alleviated, pain.
(3) do not heal: clinical symptoms does not has any alleviation.
4, result:
Selecting in the treatment group of the embodiment of the present invention 1 Chinese medicine decoction, cure 14 examples, take a turn for the better 5 examples, the most 1 example, cure rate 70%, always Effective percentage 95%.Average cure time 20.5 days.Healing and improvement patient are followed the tracks of and follows up a case by regular visits to 24 months, without 1 example recurrence.
Curing 8 examples in matched group, take a turn for the better 8 examples, the most 4 examples, cure rate 40%, total effective rate 80%.Average cure time 28 My god.Healing and improvement patient are followed the tracks of and follows up a case by regular visits to 24 months, 2 examples recurrences.
Result above shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Embodiment 2
Radix Achyranthis Bidentatae 8 grams, Dalbergia odorifera 9 grams, poison creeper 10 grams, Ramulus Cinnamomi 11 grams, 11 grams of Herba Ephedrae, Rhizoma Zingiberis 4 grams, Herba Taxilli 8 grams, Radix Stephaniae Tetrandrae 7 grams, Caulis Lonicerae 6 grams, Herba Murdanniae Divergentis 12 grams, Rhizoma Alismatis 9 grams, 8 grams of Radix Glycyrrhizae, inferior 10 grams of corruption, 6 grams of black Mulberry, the Cortex Eucommiae 5 grams, Folium Alstoniae Scholaris 6 grams, Ramulus et Folium Tamaricis Reality 12 grams, Folium Ilicis Purpureae 5 grams, largespike woodnettle root 5 grams, branch of the willow 6 grams, Semen allii fistulosi 5 grams, Fructus Corni 4 grams, river mouth lotus throne Herba pteridii latiusculi 5 grams, pittosporm root 4 Gram.Preparation method is with embodiment 1.
In 10 patients with ankylosing spondylitis of the Chinese medicine decoction that the selection embodiment of the present invention 2 is made, cure 5 examples, improvement 3 Example, the most 2 examples, cure rate 50%, total effective rate 80%.Healing and improvement patient are followed the tracks of and follows up a case by regular visits to 24 months, 1 example recurrence.
Embodiment 3
Radix Achyranthis Bidentatae 8 grams, Dalbergia odorifera 9 grams, poison creeper 10 grams, Ramulus Cinnamomi 11 grams, 11 grams of Herba Ephedrae, Rhizoma Zingiberis 4 grams, Herba Taxilli 8 grams, Radix Stephaniae Tetrandrae 7 grams, Caulis Lonicerae 6 grams, Herba Murdanniae Divergentis 12 grams, Rhizoma Alismatis 9 grams, 8 grams of Radix Glycyrrhizae, inferior 10 grams of corruption, 6 grams of black Mulberry, the Cortex Eucommiae 5 grams, Folium Alstoniae Scholaris 6 grams, Ramulus et Folium Tamaricis Reality 12 grams, Folium Ilicis Purpureae 5 grams, largespike woodnettle root 5 grams, branch of the willow 6 grams, Semen allii fistulosi 5 grams, Fructus Corni 4 grams, river mouth lotus throne Herba pteridii latiusculi 5 grams, pittosporm root 4 Gram.Preparation method is with embodiment 1.
In 12 patients with ankylosing spondylitis of the Chinese medicine decoction that the selection embodiment of the present invention 3 is made, cure 6 examples, improvement 2 Example, the most 2 examples, cure rate 60%, total effective rate 80%.Healing and improvement patient are followed the tracks of and follows up a case by regular visits to 24 months, 2 examples recurrences.
Embodiment 4
Radix Achyranthis Bidentatae 8 grams, Dalbergia odorifera 9 grams, poison creeper 10 grams, Ramulus Cinnamomi 11 grams, 11 grams of Herba Ephedrae, Rhizoma Zingiberis 4 grams, Herba Taxilli 8 grams, Radix Stephaniae Tetrandrae 7 grams, Caulis Lonicerae 6 grams, Herba Murdanniae Divergentis 12 grams, Rhizoma Alismatis 9 grams, 8 grams of Radix Glycyrrhizae, inferior 10 grams of corruption, 6 grams of black Mulberry, the Cortex Eucommiae 5 grams, Folium Alstoniae Scholaris 6 grams, Ramulus et Folium Tamaricis Reality 12 grams, Folium Ilicis Purpureae 5 grams, largespike woodnettle root 5 grams, branch of the willow 6 grams, Semen allii fistulosi 5 grams, Fructus Corni 4 grams, river mouth lotus throne Herba pteridii latiusculi 5 grams, pittosporm root 4 Gram.Preparation method is with embodiment 1.
Embodiment 5
Radix Achyranthis Bidentatae 8 grams, Dalbergia odorifera 9 grams, poison creeper 10 grams, Ramulus Cinnamomi 11 grams, 11 grams of Herba Ephedrae, Rhizoma Zingiberis 4 grams, Herba Taxilli 8 grams, Radix Stephaniae Tetrandrae 7 grams, Caulis Lonicerae 6 grams, Herba Murdanniae Divergentis 12 grams, Rhizoma Alismatis 9 grams, 8 grams of Radix Glycyrrhizae, inferior 10 grams of corruption, 6 grams of black Mulberry, the Cortex Eucommiae 5 grams, Folium Alstoniae Scholaris 6 grams, Ramulus et Folium Tamaricis Reality 12 grams, Folium Ilicis Purpureae 5 grams, largespike woodnettle root 5 grams, branch of the willow 6 grams, Semen allii fistulosi 5 grams, Fructus Corni 4 grams, river mouth lotus throne Herba pteridii latiusculi 5 grams, pittosporm root 4 Gram.Preparation method is with embodiment 1.
Embodiment 6
Radix Achyranthis Bidentatae 8 grams, Dalbergia odorifera 9 grams, poison creeper 10 grams, Ramulus Cinnamomi 11 grams, 11 grams of Herba Ephedrae, Rhizoma Zingiberis 4 grams, Herba Taxilli 8 grams, Radix Stephaniae Tetrandrae 7 grams, Caulis Lonicerae 6 grams, Herba Murdanniae Divergentis 12 grams, Rhizoma Alismatis 9 grams, 8 grams of Radix Glycyrrhizae, inferior 10 grams of corruption, 6 grams of black Mulberry, the Cortex Eucommiae 5 grams, Folium Alstoniae Scholaris 6 grams, Ramulus et Folium Tamaricis Reality 12 grams, Folium Ilicis Purpureae 5 grams, largespike woodnettle root 5 grams, branch of the willow 6 grams, Semen allii fistulosi 5 grams, Fructus Corni 4 grams, river mouth lotus throne Herba pteridii latiusculi 5 grams, pittosporm root 4 Gram.Preparation method is with embodiment 1.
Embodiment 7
Radix Achyranthis Bidentatae 8 grams, Dalbergia odorifera 9 grams, poison creeper 10 grams, Ramulus Cinnamomi 11 grams, 11 grams of Herba Ephedrae, Rhizoma Zingiberis 4 grams, Herba Taxilli 8 grams, Radix Stephaniae Tetrandrae 7 grams, Caulis Lonicerae 6 grams, Herba Murdanniae Divergentis 12 grams, Rhizoma Alismatis 9 grams, 8 grams of Radix Glycyrrhizae, inferior 10 grams of corruption, 6 grams of black Mulberry, the Cortex Eucommiae 5 grams, Folium Alstoniae Scholaris 6 grams, Ramulus et Folium Tamaricis Reality 12 grams, Folium Ilicis Purpureae 5 grams, largespike woodnettle root 5 grams, branch of the willow 6 grams, Semen allii fistulosi 5 grams, Fructus Corni 4 grams, river mouth lotus throne Herba pteridii latiusculi 5 grams, pittosporm root 4 Gram.Preparation method is with embodiment 1.
Embodiment 8
Radix Achyranthis Bidentatae 8 grams, Dalbergia odorifera 9 grams, poison creeper 10 grams, Ramulus Cinnamomi 11 grams, 11 grams of Herba Ephedrae, Rhizoma Zingiberis 4 grams, Herba Taxilli 8 grams, Radix Stephaniae Tetrandrae 7 grams, Caulis Lonicerae 6 grams, Herba Murdanniae Divergentis 12 grams, Rhizoma Alismatis 9 grams, 8 grams of Radix Glycyrrhizae, inferior 10 grams of corruption, 6 grams of black Mulberry, the Cortex Eucommiae 5 grams, Folium Alstoniae Scholaris 6 grams, Ramulus et Folium Tamaricis Reality 12 grams, Folium Ilicis Purpureae 5 grams, largespike woodnettle root 5 grams, branch of the willow 6 grams, Semen allii fistulosi 5 grams, Fructus Corni 4 grams, river mouth lotus throne Herba pteridii latiusculi 5 grams, pittosporm root 4 Gram.Preparation method is with embodiment 1.
Selecting the patients with ankylosing spondylitis 20 example clinical observation in my institute's diagnosis and treatment, clinical symptoms all meets rigid spine Scorching diagnosis and treatment standard.Patient is randomly divided into 5 groups, takes the Chinese medicine decoction that embodiment of the present invention 4-8 is made respectively, oral, every day 2 Secondary, the most each 1 time, each 100ml, record curative effect is as follows:
Case Cure Take a turn for the better Do not heal Untoward reaction Recur in 2 years Average cure time
Embodiment 4 4 3 1 0 0 1 29 days
Embodiment 5 4 3 1 0 0 1 28 days
Embodiment 6 4 4 0 0 0 0 24 days
Embodiment 7 4 4 0 0 0 0 21 days
Embodiment 8 4 4 0 0 0 0 18 days
Obviously, the above embodiment of the present invention is only for clearly demonstrating example of the present invention, and is not to this The restriction of bright embodiment, the such as present invention, in addition to making decoction agent, can also be used with common technology and make other peroral dosage forms.Phase Close Chinese medicine and pharmacology thereof all can be obtained by existing open source literature and network, it is also possible to the medical material by close effect is the most alternative. For those of ordinary skill in the field, the change of other multi-form can also be made on the basis of the above description Or variation.Here cannot all of embodiment be given exhaustive.Every belong to that technical scheme extended out aobvious And the change being clear to or variation are still in the row of protection scope of the present invention.

Claims (3)

1. the Chinese medicine decoction being used for treating ankylosing spondylitis, it is characterised in that by the Chinese crude drug system of following weight proportion For forming: Radix Achyranthis Bidentatae 8 parts, Dalbergia odorifera 9 parts, poison creeper 10 parts, Ramulus Cinnamomi 11 parts, 11 parts of Herba Ephedrae, Rhizoma Zingiberis 4 parts, Herba Taxilli 8 parts, Radix Stephaniae Tetrandrae 7 Part, Caulis Lonicerae 6 parts, Herba Murdanniae Divergentis 12 parts, Rhizoma Alismatis 9 parts, 8 parts of Radix Glycyrrhizae, inferior 10 parts of corruption, 6 parts of black Mulberry, the Cortex Eucommiae 5 parts, Folium Alstoniae Scholaris 6 parts, Gui Real 12 parts of willow, Folium Ilicis Purpureae 5 parts, largespike woodnettle root 5 parts, branch of the willow 6 parts, Semen allii fistulosi 5 parts, Fructus Corni 4 parts, river mouth lotus throne Herba pteridii latiusculi 5 parts, pittosporm root 4 parts.
The preparation method of a kind of Chinese medicine decoction for treating ankylosing spondylitis the most according to claim 1, its feature It is, above-mentioned pulverizing medicinal materials is become coarse powder;Decoct twice, decoct 8 times amount that add water for the first time, soak 2h, decoct 3h, filter;The Secondary decocts 6 times amount that add water, and decocts 2h, filters;Merge subpackage after twice decocting liquid mix homogeneously.
The Chinese medicine decoction the most according to claim 1 purposes in preparation treatment or prevention ankylosing spondylitis medicine.
CN201610764996.2A 2016-08-31 2016-08-31 A kind of Chinese medicine decoction for treating ankylosing spondylitis Pending CN106237290A (en)

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Application publication date: 20161221