CN106110084A - A kind of Chinese medicine composition for treating pet dog anorexia - Google Patents

A kind of Chinese medicine composition for treating pet dog anorexia Download PDF

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Publication number
CN106110084A
CN106110084A CN201610777585.7A CN201610777585A CN106110084A CN 106110084 A CN106110084 A CN 106110084A CN 201610777585 A CN201610777585 A CN 201610777585A CN 106110084 A CN106110084 A CN 106110084A
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CN
China
Prior art keywords
anorexia
pet dog
rhizoma
chinese medicine
medicine composition
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Pending
Application number
CN201610777585.7A
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Chinese (zh)
Inventor
付春香
刘拓
刘桂兰
刘爱玲
李旭东
夏雪林
汪美泉
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Tianjin Ringpu Bio Technology Co Ltd
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Tianjin Ringpu Bio Technology Co Ltd
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Priority to CN201610777585.7A priority Critical patent/CN106110084A/en
Publication of CN106110084A publication Critical patent/CN106110084A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994—Coix (Job's tears)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses a kind of Chinese medicine composition treating pet dog anorexia.Described compositions is by the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Semen Coicis, Radix Scutellariae, Rhizoma Corydalis, Folium Sennae, Radix Glycyrrhizae and astragalus polysaccharides.Clinical tests prove that, said composition can effectively treat pet dog anorexia.

Description

A kind of Chinese medicine composition for treating pet dog anorexia
Technical field
The present invention relates to one and treat pet dog anorexia, and the Chinese medicine composition of energy enhancing human body immunity power.
Background technology
Seeming of modern society pet dog is lived very simply, except food and drink, it is simply that look for a comfortable place to sleep, one day Time dismiss like this.But perhaps owners do not know, will be according to the physiological stage of Canis familiaris L. and body condition during raising And concrete manifestation, draft the scheme that reasonably feeds, to ensure supply balanced in nutrition by feeding standard regulation.Some owners every day Feeding time is not fixed, and greasy thing is more, allows Canis familiaris L. Canis familiaris L. reach crapulent situation, is so easy to cause Canis familiaris L. Anorexia situation, if things go on like this causes the immunity degradation of Canis familiaris L. Canis familiaris L..
The invention discloses a kind of Chinese medicine composition treating pet dog anorexia for such situation, compositions is by vain Art, Rhizoma Dioscoreae, Semen Coicis, Radix Scutellariae, Rhizoma Corydalis, Folium Sennae, Radix Glycyrrhizae and astragalus polysaccharides composition.Wherein astragalus polysaccharides not only can significantly increase Strong non-specific immunity and humoral immune function can also be by regulation content and promotion phosphatidylinositol metabolism.Senna fruit Leaf has antibacterial action and few with for bitter tonic, energy facilitating digestion.Clinical tests prove that, this prescription effect apparently without Side effect and pet dog owner's plenty of time will not be taken；Meeting outside the edible required nutrition of pet dog, moreover it is possible to be improved its Immunity, and cheap, dog owner will not be caused big burden.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine composition treating pet dog anorexia.
Described compositions includes the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Semen Coicis, Radix Scutellariae, Rhizoma Corydalis, Folium Sennae, Radix Glycyrrhizae and astragalus polysaccharides.
The formula of described compositions is: Rhizoma Atractylodis Macrocephalae 4-9g, Rhizoma Dioscoreae 3-6g, Semen Coicis 1-3g, Radix Scutellariae 1-4g, Rhizoma Corydalis 2-6g, Folium Sennae 1-3g, Radix Glycyrrhizae 1-5g and astragalus polysaccharides 2-5g.
The formula of described compositions is preferably: Rhizoma Atractylodis Macrocephalae 6g, Rhizoma Dioscoreae 4g, Semen Coicis 2g, Radix Scutellariae 2g, Rhizoma Corydalis 2g, Folium Sennae 2g, Radix Glycyrrhizae 3g and astragalus polysaccharides 3g.
Described compositions is completed by following preparation technology:
The each composition weight of compositions is weighed according to recipe quantity, boiling twice, for the first time 8 times of water, for the second time 6 times of water, Keeping micro-boiling 2 hours after boiling, 200 mesh filter screens filter while hot every time；Merge twice filtrate.Add at a temperature of 40 DEG C after mixing 1% sodium alginate, filters after stirring 1h, and the relative density being concentrated into medicinal liquid is 1.1-1.2, and cold preservation 24 hours adds water and is settled to Every milliliter is equivalent to crude drug in whole 1g, to obtain final product.
Beneficial effects of the present invention:
This invention compatibility rationally, have no side effect, effective ingredient, simple to operate can be retained at technical study efficiently, Can treat the anorexia of Canis familiaris L. well, improve immunity of organisms, medical material is generally easy to get, and preparation technology is simple, it is adaptable to expand metaplasia Produce.
Detailed description of the invention:
Embodiment 1
Embodiment 2
Embodiment 3
Embodiment 4
Preparation method:
(1) each composition weight of compositions is weighed according to embodiment 1 recipe quantity, boiling twice, for the first time 128L water, Secondary 96L water, keeps micro-boiling 2 hours every time after boiling, 200 mesh filter screens filter while hot.Merge twice filtrate, at 40 DEG C after mixing At a temperature of add 160g sodium alginate, stirring 1h after filter, the relative density being concentrated into medicinal liquid is 1.1-1.2, cold preservation 24 hours, Add water and be settled to 16L, obtain (every milliliter is equivalent to crude drug in whole 1g).
(2) each composition weight of compositions is weighed according to embodiment 2 recipe quantity, boiling twice, for the first time 336L water, Secondary 252L water, keeps micro-boiling 2 hours every time after boiling, 200 mesh filter screens filter while hot.Merge twice filtrate, at 40 DEG C after mixing At a temperature of add 420g sodium alginate, stirring 1h after filter, the relative density being concentrated into medicinal liquid is 1.1-1.2, and cold preservation 24 is little Time, add water and be settled to 42L, obtain (every milliliter is equivalent to crude drug in whole 1g).
(3) each composition weight of compositions is weighed according to embodiment 3 recipe quantity, boiling twice, for the first time 784L water, Secondary 588L water, keeps micro-boiling 2 hours every time after boiling, 200 mesh filter screens filter while hot.Merge twice filtrate, at 40 DEG C after mixing At a temperature of add 980g sodium alginate, stirring 1h after filter, the relative density being concentrated into medicinal liquid is 1.1-1.2, and cold preservation 24 is little Time, add water and be settled to 98L, obtain (every milliliter is equivalent to crude drug in whole 1g).
(4) each composition weight of compositions is weighed according to embodiment 4 recipe quantity, boiling twice, for the first time 688L water, Secondary 516L water, keeps micro-boiling 2 hours every time after boiling, 200 mesh filter screens filter while hot.Merge twice filtrate, at 40 DEG C after mixing At a temperature of add 860g sodium alginate, stirring 1h after filter, the relative density being concentrated into medicinal liquid is 1.1-1.2, and cold preservation 24 is little Time, add water and be settled to 86L, obtain (every milliliter is equivalent to crude drug in whole 1g).
Embodiment 5 chooses the pet dog of 12 anorexia in certain pet clinic, for the present composition to pet dog anorexia The clinical trial that phenomenon treatment is carried out:
1. experiment material
1.1 compositionss using the proportions in embodiment 2.
1.2 pet dogs selected:
Numbering Kind Sex Body weight (kg)
1 Basenji Male 16
2 Sa Mo Female 40
3 Gold hair Female 50
4 Doberman Male 55
5 Ace base rubs Male 52
6 Chinese sharpei Male 31
7 Pine lion Male 50
8 Labrador Female 48
9 Canis lupus familiaris Female 64
10 Speckle Canis familiaris L. Male 36
11 Compare lattice Male 28
12 Pekinese Female 11
2. method
Body weight according to Canis familiaris L. is administered according to 1g/kg (according to crude drug in whole meter), 2 times on the one, takes continuously 15 days, inspection in every 5 days Surveying body weight and biochemistry refers to, body weight and health degree are shown in Tables 1 and 2；
Table one: the body weights of Canis familiaris L.
Table two: the blood biochemistry index of Canis familiaris L.
Observe each Canis familiaris L. during 5 days upon administration, 10 days and 15 days to be relatively administered front obvious active active appetite and significantly improve, Show that the anorexia of pet dog can effectively be treated by Chinese medicine of the present invention from data above.

Claims (4)

1. one kind for treating the Chinese medicine composition of pet dog anorexia, it is characterised in that described compositions include the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Semen Coicis, Radix Scutellariae, Rhizoma Corydalis, Folium Sennae, Radix Glycyrrhizae and astragalus polysaccharides.
A kind of Chinese medicine composition for treating pet dog anorexia the most according to claim 1, it is characterised in that described group The formula of compound is: Rhizoma Atractylodis Macrocephalae 4-9g, Rhizoma Dioscoreae 3-6g, Semen Coicis 1-3g, Radix Scutellariae 1-4g, Rhizoma Corydalis 2-6g, Folium Sennae 1-3g, Radix Glycyrrhizae 1-5g and astragalus polysaccharides 2-5g.
The most according to claim 2 a kind of for treating the pharmaceutical composition that pet dog is fat, it is characterised in that described group The formula of compound is: Rhizoma Atractylodis Macrocephalae 6g, Rhizoma Dioscoreae 4g, Semen Coicis 2g, Radix Scutellariae 2g, Rhizoma Corydalis 2g, Folium Sennae 2g, Radix Glycyrrhizae 3g and astragalus polysaccharides 3g。
4. according to the arbitrary described a kind of Chinese medicine composition for treating pet dog anorexia of claims 1 to 3, it is characterised in that Completed by following preparation technology:
The each composition weight of compositions is weighed according to recipe quantity, boiling twice, for the first time 8 times of water, for the second time 6 times of water, every time Keeping micro-boiling 2 hours after boiling, 200 mesh filter screens filter while hot；Merge twice filtrate.At a temperature of 40 DEG C, 1% is added after mixing Sodium alginate, stirring 1h filters, and the relative density being concentrated into medicinal liquid is 1.1-1.2, and cold preservation 24 hours adds water and is settled to every milliliter Be equivalent to crude drug in whole 1g, to obtain final product.
CN201610777585.7A 2016-08-31 2016-08-31 A kind of Chinese medicine composition for treating pet dog anorexia Pending CN106110084A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102861265A (en) * 2012-09-22 2013-01-09 南京正亮医药科技有限公司 Medicinal tea for treating apocleisis and preparation method and application
CN104248703A (en) * 2013-06-26 2014-12-31 瑞普（天津）生物药业有限公司 Traditional Chinese medicine composition for treating mycoplasma gallisepticum infection
CN104474202A (en) * 2014-12-04 2015-04-01 邹士东 Pharmaceutical composition for treating anorexia
CN105456406A (en) * 2014-09-12 2016-04-06 瑞普（天津）生物药业有限公司 Medicinal composition capable of improving autoimmunity of poultry
CN105726872A (en) * 2014-12-10 2016-07-06 瑞普（天津）生物药业有限公司 Medicinal composition for treating obesity of pet dogs

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102861265A (en) * 2012-09-22 2013-01-09 南京正亮医药科技有限公司 Medicinal tea for treating apocleisis and preparation method and application
CN104248703A (en) * 2013-06-26 2014-12-31 瑞普（天津）生物药业有限公司 Traditional Chinese medicine composition for treating mycoplasma gallisepticum infection
CN105456406A (en) * 2014-09-12 2016-04-06 瑞普（天津）生物药业有限公司 Medicinal composition capable of improving autoimmunity of poultry
CN104474202A (en) * 2014-12-04 2015-04-01 邹士东 Pharmaceutical composition for treating anorexia
CN105726872A (en) * 2014-12-10 2016-07-06 瑞普（天津）生物药业有限公司 Medicinal composition for treating obesity of pet dogs

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
曾俊: "番泻叶的不良反应", 《现代医药卫生》 *
葛秀英等: "《参苓白术散加味治疗小儿厌食症36例》", 31 December 2006 *

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Application publication date: 20161116