CN102861265A - Medicinal tea for treating apocleisis and preparation method and application - Google Patents
Medicinal tea for treating apocleisis and preparation method and application Download PDFInfo
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- CN102861265A CN102861265A CN2012103561403A CN201210356140A CN102861265A CN 102861265 A CN102861265 A CN 102861265A CN 2012103561403 A CN2012103561403 A CN 2012103561403A CN 201210356140 A CN201210356140 A CN 201210356140A CN 102861265 A CN102861265 A CN 102861265A
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Abstract
The invention provides medicinal tea for treating apocleisis, which is prepared form the raw materials in part by weight: 8 to 12 parts of rhizoma atractylodis macrocephalae, 18 to 22 parts of rhizoma dioscoreae, 10 to 14 parts of codonopsis pilosula, 8 to 12 parts of fructus aurantii immaturus, 10 to 14 parts of fructus hordei germinatus, 18 to 22 parts of ficus carica, 18 to 22 parts of concha ostreae, 6 to 10 parts of cluster mallow fruit, 8 to 12 parts of neolitsea umbtosa gamble and 10 to 14 parts of semen raphani. A medicinal tea bag is obtained by drying, grinding and uniformly mixing the raw materials according to a conventional tea bag production technology. The medicinal tea for treating apocleisis, provided by the invention, has the effects of tonifying Qi and spleen, which is utilized to treat apocleisis.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of medicated tea and preparation method and application that are used for the treatment of anorexia.
Background technology
Apositia refers generally to see for a long time that food do not think, and appetite is not opened, inappetence, even a kind of disease of refusing to eat.This disease mainly is because due to the improper diet, deficiency of spleen-QI and stomach-QI, gastrointestinal function disorder.This disease is not controlled can affect growth promoter, reduces immunity, concurrent other diseases.At present, the medicine for the treatment of apositia both at home and abroad is more, but has the shortcomings such as drug price is high, medical expense is large, effect is not ideal enough.Such as Hu Guoliang (application number: 200610121196.5) a kind of decoction medicine and preparation method for the treatment of insufficiency of the spleen stomach-cold type apositia of application, relate to the Chinese herbal medicine formula for the treatment of insufficiency of the spleen stomach-cold type apositia, contain Radix Pseudostellariae, Fructus Setariae Germinatus (parched), each 13-15 gram of Fructus Hordei Germinatus (parched), the Radix Astragali, each 10-l2 gram of Poria, Endothelium Corneum Gigeriae Galli, each 8-10 gram of Massa Medicata Fermentata, Semen Alpiniae Katsumadai, each 4-6 gram of Rhizoma Zingiberis, said herbal medicine is through organic assembling, dialectical compatibility and mutually assisting a ruler in governing a country, strengthened this medicine tonify deficiency QI invigorating, the effect of invigorating the spleen and regulating the stomach, thereby reach the purpose of curing insufficiency of the spleen stomach-cold type apositia, but not through pharmacology's checking.
Summary of the invention
Goal of the invention: in order to address the above problem, the object of the present invention is to provide a kind of medicated tea and preparation method and application that are used for the treatment of anorexia.
Technical scheme: the objective of the invention is to realize by following scheme:
A kind of medicated tea that is used for the treatment of anorexia, it is prepared by the raw material of following parts by weight: Rhizoma Atractylodis Macrocephalae 8-12 part, Rhizoma Dioscoreae 18-22 part, Radix Codonopsis 10-14 part, Fructus Aurantii Immaturus 8-12 part, Fructus Hordei Germinatus 10-14 part, Fructus Fici 18-22 part, Concha Ostreae 18-22 part, Semen Abutili 6-10 part, little Fructus Litseae pungentis 8-12 part, Semen Raphani 10-14 part, drying, pulverizing, and mix homogeneously, adopt conventional production process of bagged tea, bagged medicine tea is made in pack again.
The above-mentioned medicated tea that is used for the treatment of anorexia, it is prepared by the raw material of following parts by weight: 10 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts of Rhizoma Dioscoreaes, 12 parts of Radix Codonopsis, 10 parts of Fructus Aurantii Immaturuss, 12 parts in Fructus Hordei Germinatus, 20 parts of Fructus Ficis, 20 parts of Concha Ostreaes, 8 parts of Semen Abutilis, 10 parts of little Fructus Litseae pungentiss, 12 parts of Semen Raphanis, drying, pulverizing, and mix homogeneously, adopt conventional production process of bagged tea, bagged medicine tea is made in pack again.
The above-mentioned application of medicated tea in preparation treatment anorexia medicated tea that is used for the treatment of anorexia.
Beneficial effect:
1, from theory of Chinese medical science, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Radix Codonopsis air making-up and spleen enlivening are the regulating qi-flowing for harmonizing stomach such as monarch drug, Fructus Aurantii Immaturus, Fructus Hordei Germinatus, Fructus Fici, elimination distension among the we, stimulating appetite be ministerial drug, Concha Ostreae, Semen Abutili, little Fructus Litseae pungentis, Semen Raphani intestinal stasis relieving and in be adjuvant, all medicines are harmonious, play altogether the effect of air making-up and spleen enlivening transporting, be used for the treatment of anorexia.
2, Formulation of the present invention is reasonable, and compatibility is rigorous, through long-term clinical verification, determined curative effect.
3, the present invention consists of Chinese crude drug, has no side effect low price.
The specific embodiment
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following example, all technology that realizes based on foregoing of the present invention all belong to scope of the present invention.
1, in conjunction with the specific embodiment, the present invention is further described as follows:
In the following raw material, Semen Abutili is for to be that the mature seed of Malvaceae annual herb plant Semen Abutili, little Fructus Litseae pungentis are the fruit of canella Fructus Litseae pungentis, and all the other all are selected from standards of pharmacopoeia.
Embodiment 1: get 8 parts of the Rhizoma Atractylodis Macrocephalaes, 22 parts of Rhizoma Dioscoreaes, 10 parts of Radix Codonopsis, 12 parts of Fructus Aurantii Immaturuss, 10 parts in Fructus Hordei Germinatus, 22 parts of Fructus Ficis, 18 parts of Concha Ostreaes, 10 parts of Semen Abutilis, 8 parts of little Fructus Litseae pungentiss, 14 parts of Semen Raphanis, drying, pulverizing, and mix homogeneously, adopt conventional production process of bagged tea, bagged medicine tea is made in pack again.
Embodiment 2: get 12 parts of the Rhizoma Atractylodis Macrocephalaes, 18 parts of Rhizoma Dioscoreaes, 14 parts of Radix Codonopsis, 8 parts of Fructus Aurantii Immaturuss, 14 parts in Fructus Hordei Germinatus, 18 parts of Fructus Ficis, 22 parts of Concha Ostreaes, 6 parts of Semen Abutilis, 12 parts of little Fructus Litseae pungentiss, 10 parts of Semen Raphanis, drying, pulverizing, and mix homogeneously, adopt conventional production process of bagged tea, bagged medicine tea is made in pack again.
Embodiment 3: get 10 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts of Rhizoma Dioscoreaes, 12 parts of Radix Codonopsis, 10 parts of Fructus Aurantii Immaturuss, 12 parts in Fructus Hordei Germinatus, 20 parts of Fructus Ficis, 20 parts of Concha Ostreaes, 8 parts of Semen Abutilis, 10 parts of little Fructus Litseae pungentiss, 12 parts of Semen Raphanis, drying, pulverizing, and mix homogeneously, adopt conventional production process of bagged tea, bagged medicine tea is made in pack again.
2. the present invention is on the impact of mouse small intestine ahead running
2.1 animal: healthy ICR mice, male and female half and half, heavy 18-22g is provided by Nanjing Medical University's animal center, production licence number SCXK(Soviet Union) 2002-0031.
2.2 medicine and reagent: press above-described embodiment 2 preparations medicated tea of the present invention, every bag of 10g, contain crude drug 10g/ bag, just bright Pharmaceutical Technology Co., Ltd provides by Nanjing, lot number 20110811, clinical people's consumption per day is the 20g crude drug, therefore determine that every mice consumption is the 20x0.0026=0.052g crude drug, calculate with kilogram, dosage is 2.6g crude drug/kg, and this is low dosage, dosage 5.2g crude drug/kg is middle dosage, dosage 10.4g crude drug/kg is high dose, uses the boiled water of 10 times of amounts to soak before each gavage 30 minutes, filters.
The preparation of contrast medicine: by Hu Guoliang (application number: 200610121196.5) a kind of decoction medicine and preparation method for the treatment of insufficiency of the spleen stomach-cold type apositia of application, get Radix Pseudostellariae, Fructus Setariae Germinatus (parched), each 13 gram of Fructus Hordei Germinatus (parched), the Radix Astragali, each 10 gram of Poria, Endothelium Corneum Gigeriae Galli, each 8 gram of Massa Medicata Fermentata, Semen Alpiniae Katsumadai, each 4 gram of Rhizoma Zingiberis, the preparation method of medicine is: first with the proportional quantity Radix Pseudostellariae, Fructus Setariae Germinatus (parched), Fructus Hordei Germinatus (parched), the Radix Astragali, Poria, Endothelium Corneum Gigeriae Galli, Massa Medicata Fermentata, Semen Alpiniae Katsumadai, the Chinese herbal medicine such as Rhizoma Zingiberis are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water is to surpass powder 2-3cm as degree.Enter to fry in shallow oil and front said herbal medicine is soaked half an hour, make it fully moistening, fully fried in order to medicine juice.Then, (suddenly) fire of useing force boils to be used literary composition (little) fire instead again and decocts.Stop when decocting about 20 minutes, remove medicinal residues, get filtrate, concentrated, be drying to obtain 20g dry powder, people's consumption per day 80g medical material, being equivalent to every mice consumption is 80*0.0026=0.208g crude drug amount, calculates with kilogram, dosage is 10.4g crude drug amount/kg.
The reserpine injection, ShangHai Fudan Fuhua Pharmaceutical Co., Ltd produces, lot number: 20100201, all the other reagent are domestic analytical pure.
2.3 animal, medicine and reagent are the same.
Process of the test: get 50 of ICR mices, every group about 10, male and female half and half, be divided into model group, contrast medicine group, medicated tea of the present invention is high, in, low three dosage groups, each is organized in lumbar injection reserpine 0.2mg/kg in morning every day, every afternoon model group gavage pure water 10ml/kg, contrast medicine group dosage is 10.4g crude drug amount/kg, medicated tea of the present invention is low, in, high dose group dosage is respectively 2.6,5.2,10.4g crude drug/kg, 14d tests front fasting and can't help water 12h, 2h after the last administration continuously, be that 5% charcoal end arabic gum suspension lml/g gavages with volume fraction respectively, put to death behind the 20min and respectively organize mice, cut open the belly and measure every Mus small intestinal charcoal end displacement and small intestinal total length, be converted into the percentage rate that charcoal end displacement accounts for the small intestinal total length, t test and judge group difference the results are shown in Table 1.
Table 1 medicine of the present invention is on the impact (n=10) of mouse small intestine ahead running
Compare with model group, * * P<0.01 * P<0.05 compares ##P<0.01 #P<0.05 with contrast medicine group
The result: medicine group of the present invention has obvious promotion intestinal propulsion motion, promotes the effect of gastrointestinal motility in mice, compares with the contrast medicine, and medicine group of the present invention is promoting aspect the mouse small intestine ahead running significant difference is being arranged.
Claims (3)
1. medicated tea that is used for the treatment of anorexia, it is characterized in that, it is prepared by the raw material of following parts by weight: Rhizoma Atractylodis Macrocephalae 8-12 part, Rhizoma Dioscoreae 18-22 part, Radix Codonopsis 10-14 part, Fructus Aurantii Immaturus 8-12 part, Fructus Hordei Germinatus 10-14 part, Fructus Fici 18-22 part, Concha Ostreae 18-22 part, Semen Abutili 6-10 part, little Fructus Litseae pungentis 8-12 part, Semen Raphani 10-14 part, drying, pulverizing, and mix homogeneously, adopt conventional production process of bagged tea, bagged medicine tea is made in pack again.
2. the medicated tea that is used for the treatment of anorexia according to claim 1, it is characterized in that, it is prepared by the raw material of following parts by weight: 10 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts of Rhizoma Dioscoreaes, 12 parts of Radix Codonopsis, 10 parts of Fructus Aurantii Immaturuss, 12 parts in Fructus Hordei Germinatus, 20 parts of Fructus Ficis, 20 parts of Concha Ostreaes, 8 parts of Semen Abutilis, 10 parts of little Fructus Litseae pungentiss, 12 parts of Semen Raphanis, drying, pulverizing, and mix homogeneously, adopt conventional production process of bagged tea, bagged medicine tea is made in pack again.
3. the according to claim 1 described application of medicated tea in preparation treatment anorexia medicated tea that is used for the treatment of anorexia.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106110084A (en) * | 2016-08-31 | 2016-11-16 | 瑞普(天津)生物药业有限公司 | A kind of Chinese medicine composition for treating pet dog anorexia |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106110084A (en) * | 2016-08-31 | 2016-11-16 | 瑞普(天津)生物药业有限公司 | A kind of Chinese medicine composition for treating pet dog anorexia |
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Application publication date: 20130109 |