CN106109918A - A kind of antibacterial micro-ferment sealwort decoction piece of skin care QI invigorating and preparation method thereof - Google Patents
A kind of antibacterial micro-ferment sealwort decoction piece of skin care QI invigorating and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
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Abstract
The invention discloses a kind of antibacterial micro-ferment sealwort decoction piece of skin care QI invigorating and preparation method thereof, be made up of following raw materials in part by weight: Rhizoma Polygonati 50 60, collagen protein powder 30 35, propolis 13 15, rice bran protein powder 130 150, processed with wine Fructus Lycii 20 23, Semen Armeniacae Amarum 15 18, Semen Phaseoli 15 18, mulberry juice 50 60, Os Gallus Domesticus 50 60, Chinese liquor 30 35, Herba Boschniakiae Rossicae 10 12, mandarin oil 13 15.The antibacterial micro-ferment sealwort decoction piece of a kind of skin care QI invigorating of the present invention, contained effective ingredient has the functions such as skin care, QI invigorating, antibacterial, cough-relieving.
Description
Technical field
The present invention relates to prepared slices of Chinese crude drugs technical field, particularly relate to a kind of antibacterial micro-ferment sealwort decoction piece of skin care QI invigorating and system thereof
Preparation Method.
Background technology
The prepared slices of Chinese crude drugs are under guidance of traditional Chinese medicine theory, according to determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs principle and the needs of formulation dispensing, to Chinese medicine
The finished product of material Processing methods is tcm clinical practice medication, play dialectical plus-minus, embody the basis of personalized medicine principle.Chinese medicine is drunk
Sheet is one of big pillar of Chinese herbal medicine industry three, the important component part of Ye Shi China traditional medicine, diseases prevention, cure the disease in play
Important effect.Therefore the quality of The Quality of Sliced Herbal Medicine is by directly influencing the effect of tcm clinical practice treatment, has influence on the people
Masses' life and health and the safety of medication.
Chinese medicine wall cell disruption powder body and Chinese medicine wall cell disruption decoction pieces are the modern developments of Chinese medicinal powder application, the utilization rate of its material base
More traditional decoction pieces has a more substantial increase.Research work expands around association area and studies more than the tackling key problem of 300 sub-problems.
The Chinese crude drug overwhelming majority derives from natural plant, derives from animal, mineral and artifact on a small quantity.And plant medicine material
Being respectively provided with cell wall structure, use traditional decoction extracting mode, cell wall can stop intracellular active substance to a great extent
Dissolution, causes active ingredients from traditional Chinese medicinal utilization rate low, serious waste of resources.Chinese medicine wall cell disruption decoction pieces is broken by modern crushing technology
Cell wall, allows the material in cell wall be prone to dissolution and mix homogeneously, can be effectively improved Chinese crude drug because of its position and tissue etc. no
The problem of the material base inhomogeneities caused together, improves leaching rate and the utilization rate of effective ingredient in medical material, also achieves
Chinese medicine without long-time high temperature decoct extract process, and apply convenient.And in traditional Chinese herbs broken wall link, rational breaking cell wall
Diameter of particle is that it is crucial.The diameter of general cell is all about 10-100 μm.After being processed by cellular level pulverizing, in inciting somebody to action
Pulverizing medicinal materials is to 300 mesh (sieve aperture internal diameter is 47 μm), and cell-wall breaking ratio can reach 86.5%.The 300 above Chinese traditional powder of mesh, 98% is micro-
Powder can only see cell debris.The medium particle diameter that general 300 mesh Chinese medicinal powder microscope inspections measure is 4-10 μm.This grain
The ultrafine Chinese herb in footpath can make its components utilising rate improve to 60-90%.From economic and technical comprehensive examination and evaluation, Chinese medicine wall cell disruption decoction pieces selects
Selecting micronizing and be machined to D90 < 45 μm, < powder body of 45 μm (more than 300 mesh) breaks the diameter of particle of i.e. more than 90% as Chinese medicine
The standard of wall powder body.This breaking cell wall processes and belongs to fine physical refining process, intracellular material composition is not caused matter
Change.The wall breaking pulverization technology of Chinese medicine is the most mature in the industry two classes: one has rigid solid medium to participate in, by hitting
Hit, shear, the conventional size reduction principle such as friction breaks the technology of cell wall；Two do not have rigid solid medium to participate in, and utilize strong
Strong air-flow breaks the technology of cell wall by Chinese traditional powder self high frequency, fast ram.The pulverizing skill that rigid solid medium participates in
The feature of art is: medium, owing to being clashed into and rubbing, easy to wear comes off, and pollutes medical material；When medium high-speed impact, shearing medical material
, make medical material produce higher temperature, be unfavorable for the protection of heat-sensitive ingredients；But the subject range width that this technology is to medical material, to material
Physical property requires low.The feature of airflow pulverization is: do not have rigid solid medium contacting material, the suction of air-flow high speed pay-out
The heat production of heat and material impacting is offset, and material does not heats up at crushing process, so that heat-sensitive ingredients is effectively protected；But air-flow
The physical property of material is required higher by crushing technology, and subject range is narrower.For ensureing to greatest extent to process through cell wall breaking
Chinese traditional powder pollution-free, do not heat up, Chinese medicine wall cell disruption decoction pieces select airflow pulverization realize breaking cell wall.Chinese medicine wall cell disruption decoction pieces
After wall breaking pulverization processes, define the specific surface area moisture absorption big, easy, oxidizable and the powder body of poor fluidity, extremely unstable and difficulty
To meet the industrialized production requirement to its mobility.Therefore, allow Chinese medicine wall cell disruption powder body after breaking cellular wall again molding with reduce ratio
Surface area, improves the key problem in technology that stability is exactly its industrialization.
Summary of the invention
The object of the invention is contemplated to make up the defect of prior art, it is provided that a kind of skin care QI invigorating antibacterial micro-ferment Rhizoma Polygonati drink
Sheet.
The present invention is achieved by the following technical solutions:
A kind of antibacterial micro-ferment sealwort decoction piece of skin care QI invigorating, is made up of following raw materials in part by weight:
Rhizoma Polygonati 50-60, collagen protein powder 30-35, propolis 13-15, rice bran protein powder 130-150, processed with wine Fructus Lycii 20-23, bitter Fructus Pruni
Core 15-18, Semen Phaseoli 15-18, mulberry juice 50-60, Os Gallus Domesticus 50-60, Chinese liquor 30-35, Herba Boschniakiae Rossicae 10-12, mandarin oil 13-
15。
The antibacterial micro-ferment sealwort decoction piece of described a kind of skin care QI invigorating, is made up of the following step:
1), processed with wine Fructus Lycii, Herba Boschniakiae Rossicae, Os Gallus Domesticus, propolis, Chinese liquor being added in steamer, decoct altogether twice, the decoction liquor after filter takes
Go out, load in clean container；
2), by Rhizoma Polygonati, Semen Armeniacae Amarum, Semen Phaseoli mix homogeneously in rustless steel container, and put into pulverizer, be ground into fine powder
Rear 100-120 mesh sieve of crossing, recycling airflow pulverization, it is carried out fining-off so that it is reach 300-350 mesh；
3), step 2 gained mixture is added in mixer with mulberry juice, collagen protein powder, rice bran protein powder, wait to be sufficiently mixed
After, the mixing decoction liquor adding step 1 gained is stirred soft material processed, stirs 15-20 minute；
4), by step 3 gains taking out puts in stainless steel disc, adds mandarin oil mix homogeneously, piles up in heaps, and light is patted on surface
Sliding, cover tightly with non-woven fabrics, be 30-35 DEG C, humidity 70-80% in temperature, ferment, after 3-4 days, treat that stockpile surface is uniformly given birth to
Go out white mould clothing, and crackle occurs, break section into two with one's hands when having cellular, fermented standby；
5) mixture, by step 4 fermented is whole broken, puts in molding device, operates by molding device standard operating procedure, cuts
Become the cubed pieces of the long 1.0-1.5cm of rib；
6), by step 5 gained cubed pieces, load in a clean rustless steel drip pan, pave, must not extrude, put into hot air circulation
Drying in baking oven, operate according to heated-air circulation oven standard operating procedure, baking temperature is 70-80 DEG C, when being dried
Between be 4-5 hour, water content control is at 7-12%, after drying, takes out, cools, loads in clean container, use outer, interior two layers multiple
Closing the form of packaging, internal layer packaging is non-toxic polyethylene bag, and outer packaging is corrugated case, kept dry.
The invention have the advantage that
1, the antibacterial micro-ferment sealwort decoction piece of a kind of skin care QI invigorating of the present invention, is pulverized material by airflow pulverization, is not had
Having rigid solid medium contacting material, the heat absorption of air-flow high speed pay-out and the heat production of material impacting are offset, and material is at crushing process
Do not heat up, so that heat-sensitive ingredients is effectively protected.
2, the antibacterial micro-ferment sealwort decoction piece of a kind of skin care QI invigorating of the present invention, is replaced by collagen protein powder, rice bran protein powder
Conventional flours, carries out film-making, makes decoction pieces nutrition abundanter, mouthfeel after micro-fermentation
3, the present invention is mixed with material by mandarin oil, and heap is in heaps, and surface is patted smooth, is conducive to building the environment closed, makes
The internal anoxia of material, thus beneficially anaerobic fermentation, mandarin oil has and prevents moisture rapid evaporation, and having additional nutrients to wait acts on.
4, the antibacterial micro-ferment sealwort decoction piece of a kind of skin care QI invigorating of the present invention, contained effective ingredient has skin care, QI invigorating, presses down
The function such as bacterium, cough-relieving.
Detailed description of the invention
A kind of antibacterial micro-ferment sealwort decoction piece of skin care QI invigorating, is made up of following raw materials in part by weight:
Rhizoma Polygonati 50, collagen protein powder 30, propolis 13, rice bran protein powder 130, processed with wine Fructus Lycii 20, Semen Armeniacae Amarum 15, Semen Phaseoli 15, Mulberry
Shen juice 50, Os Gallus Domesticus 50, Chinese liquor 30, Herba Boschniakiae Rossicae 10, mandarin oil 13.
The antibacterial micro-ferment sealwort decoction piece of described a kind of skin care QI invigorating, is made up of the following step:
1), processed with wine Fructus Lycii, Herba Boschniakiae Rossicae, Os Gallus Domesticus, propolis, Chinese liquor being added in steamer, decoct altogether twice, the decoction liquor after filter takes
Go out, load in clean container；
2), by Rhizoma Polygonati, Semen Armeniacae Amarum, Semen Phaseoli mix homogeneously in rustless steel container, and put into pulverizer, be ground into fine powder
Rear mistake 100 mesh sieve, recycles airflow pulverization, it is carried out fining-off so that it is reach 320 mesh；
3), step 2 gained mixture is added in mixer with mulberry juice, collagen protein powder, rice bran protein powder, wait to be sufficiently mixed
After, the mixing decoction liquor adding step 1 gained is stirred soft material processed, stirs 15 minutes；
4), by step 3 gains taking out puts in stainless steel disc, adds mandarin oil mix homogeneously, piles up in heaps, and light is patted on surface
Sliding, cover tightly with non-woven fabrics, be 30 DEG C, humidity 70% in temperature, ferment, after 3 days, treat that white mould clothing is uniformly born on stockpile surface,
And crackle occurs, break section into two with one's hands when having cellular, fermented standby；
5) mixture, by step 4 fermented is whole broken, puts in molding device, operates by molding device standard operating procedure, cuts
Become the cubed pieces of the long 1.0cm of rib；
6), by step 5 gained cubed pieces, load in a clean rustless steel drip pan, pave, must not extrude, put into hot air circulation
Drying in baking oven, operate according to heated-air circulation oven standard operating procedure, baking temperature is 70 DEG C, and drying time is
4 hours, water content control was 7%, after drying, takes out, cools, and loaded in clean container, used outer, interior two layers of composite packaging
Form, internal layer packaging is non-toxic polyethylene bag, and outer packaging is corrugated case, kept dry.
Claims (2)
1. the antibacterial micro-ferment sealwort decoction piece of skin care QI invigorating, it is characterised in that be made up of following raw materials in part by weight:
Rhizoma Polygonati 50-60, collagen protein powder 30-35, propolis 13-15, rice bran protein powder 130-150, processed with wine Fructus Lycii 20-23, bitter Fructus Pruni
Core 15-18, Semen Phaseoli 15-18, mulberry juice 50-60, Os Gallus Domesticus 50-60, Chinese liquor 30-35, Herba Boschniakiae Rossicae 10-12, mandarin oil 13-
15。
A kind of antibacterial micro-ferment sealwort decoction piece of skin care QI invigorating the most according to claim 1, it is characterised in that be by the following step
Make:
1), processed with wine Fructus Lycii, Herba Boschniakiae Rossicae, Os Gallus Domesticus, propolis, Chinese liquor being added in steamer, decoct altogether twice, the decoction liquor after filter takes
Go out, load in clean container；
2), by Rhizoma Polygonati, Semen Armeniacae Amarum, Semen Phaseoli mix homogeneously in rustless steel container, and put into pulverizer, be ground into fine powder
Rear 100-120 mesh sieve of crossing, recycling airflow pulverization, it is carried out fining-off so that it is reach 300-350 mesh；
3), step 2 gained mixture is added in mixer with mulberry juice, collagen protein powder, rice bran protein powder, wait to be sufficiently mixed
After, the mixing decoction liquor adding step 1 gained is stirred soft material processed, stirs 15-20 minute；
4), by step 3 gains taking out puts in stainless steel disc, adds mandarin oil mix homogeneously, piles up in heaps, and light is patted on surface
Sliding, cover tightly with non-woven fabrics, be 30-35 DEG C, humidity 70-80% in temperature, ferment, after 3-4 days, treat that stockpile surface is uniformly given birth to
Go out white mould clothing, and crackle occurs, break section into two with one's hands when having cellular, fermented standby；
5) mixture, by step 4 fermented is whole broken, puts in molding device, operates by molding device standard operating procedure, cuts
Become the cubed pieces of the long 1.0-1.5cm of rib；
6), by step 5 gained cubed pieces, load in a clean rustless steel drip pan, pave, must not extrude, put into hot air circulation
Drying in baking oven, operate according to heated-air circulation oven standard operating procedure, baking temperature is 70-80 DEG C, when being dried
Between be 4-5 hour, water content control is at 7-12%, after drying, takes out, cools, loads in clean container, use outer, interior two layers multiple
Closing the form of packaging, internal layer packaging is non-toxic polyethylene bag, and outer packaging is corrugated case, kept dry.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610642877.XA CN106109918A (en) | 2016-08-09 | 2016-08-09 | A kind of antibacterial micro-ferment sealwort decoction piece of skin care QI invigorating and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610642877.XA CN106109918A (en) | 2016-08-09 | 2016-08-09 | A kind of antibacterial micro-ferment sealwort decoction piece of skin care QI invigorating and preparation method thereof |
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| CN106109918A true CN106109918A (en) | 2016-11-16 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103301311A (en) * | 2013-05-31 | 2013-09-18 | 安徽源和堂药业股份有限公司 | Preparation method of sealwort decoction piece |
| CN103432384A (en) * | 2013-08-10 | 2013-12-11 | 田克力 | Processing method of siberian solomoseal rhizome herbal pieces prepared for decoction |
| CN104324103A (en) * | 2014-10-17 | 2015-02-04 | 磐安县道地磐药中药研究所 | Medicated leaven pure powder superfine decoction piece and preparation method thereof |
-
2016
- 2016-08-09 CN CN201610642877.XA patent/CN106109918A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103301311A (en) * | 2013-05-31 | 2013-09-18 | 安徽源和堂药业股份有限公司 | Preparation method of sealwort decoction piece |
| CN103432384A (en) * | 2013-08-10 | 2013-12-11 | 田克力 | Processing method of siberian solomoseal rhizome herbal pieces prepared for decoction |
| CN104324103A (en) * | 2014-10-17 | 2015-02-04 | 磐安县道地磐药中药研究所 | Medicated leaven pure powder superfine decoction piece and preparation method thereof |
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Application publication date: 20161116 |