CN106109685A - A kind of Chinese medicine oral liquid treating hypertension and preparation method - Google Patents

A kind of Chinese medicine oral liquid treating hypertension and preparation method Download PDF

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CN106109685A
CN106109685A CN201610587159.7A CN201610587159A CN106109685A CN 106109685 A CN106109685 A CN 106109685A CN 201610587159 A CN201610587159 A CN 201610587159A CN 106109685 A CN106109685 A CN 106109685A
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parts
portions
radix
herba
chinese medicine
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王泽珩
王夕芬
王栋
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a kind of Chinese medicine oral liquid treating hypertension and preparation method, belong to the field of Chinese medicines；The raw material of Chinese medicine oral liquid effective ingredient of the present invention consists of: gold lion rattan, Rhopilema esculenta, Herba mesonae chinensis, Folium Salicis Babylonicae, Radix Stephaniae hemandifoliae, Radix Ervatamiae Hainanensis, Semen Fagopyri Esculenti, Herba Artemisiae Japonicae, SHANGZI, Auricularia, Radix cocculi laurifolii, Radix Rehmanniae Preparata, Herba menyanthis, Fructus Phyllanthi, salt alkali and Herba Spinaciae；Selected by Chinese medicine oral liquid of the present invention, medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine and pharmacology research theory, and has clearing away heat and cooling blood, toxin expelling antiinflammatory, effect of expelling wind and removing dampness, treatment hypertension had significant curative effect, short treating period, instant effect, taking convenience, safe and reliable, have no side effect, non-relapse after healing, treating both the principal and secondary aspects of a disease, can normally work and live during taking medicine, special effect is practical, and should be widely promoted application.

Description

A kind of Chinese medicine oral liquid treating hypertension and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine oral liquid treating hypertension and preparation method.
Background technology
The symptom of hypertension varies with each individual, and early stage is possible asymptomatic or symptom is inconspicuous, only can be tired, spiritual tight , occur after anxious state of mind blood pressure to raise, and recover normal after rest, along with the course of disease extends, blood pressure the most persistently raises, Gradually there will be various symptom, be now referred to as benign hypertension.The common clinical symptoms of benign hypertension has head Bitterly, dizzy, absent minded, hypomnesis, numb limbs and tense tendons, nocturia increase, cardiopalmus, uncomfortable in chest, weak etc., when blood pressure is unexpected Even there will be the symptoms such as severe headache, vomiting, cardiopalmus, dizziness when being increased to a certain degree, can occur time serious obnubilation, Twitching, this just belongs to accelerated hypertension and hypertension critical illness, and how the organs such as the serious heart, brain, kidney can occur in a short time Infringement and pathological changes, such as apoplexy, heart infarction, renal failure etc..
In recent years, people to cardiovascular diseases's multiple risk factors effect and the heart, brain, kidney target-organ protection understanding continuous Deeply, the diagnostic criteria of hypertension is also constantly adjusting, it is now recognized that the patient of same blood pressure level occurs the danger of cardiovascular diseases Danger is different, has therefore had the concept that blood pressure is layered, the patient that cardiovascular diseases's risk factor is different i.e. occurs, and suitable blood pressure level should have Different.Early stage harm headache, position is many at hindbrain, and with symptoms such as Nausea and vomiting.If often feel like headache, and the most acute Strong, feel sick the most again and feel sick, it is possible to be the signal converted to malignant hypertension；Dizziness, female patient occurs more, may Feel when squatting down or stand up suddenly；Tinnitus, ears tinnitus, the persistent period is longer；Shortness of breath and palpitation, hypertension can cause the heart Flesh plumpness, cardiac dilatation, myocardial infarction, cardiac insufficiency, these are all the symptoms causing shortness of breath and palpitation；Insomnia, mostly is sleep Difficulty, early awakening, sleep is the most steady and sure, easily have horrible nightmares, easily wake up with a start.This lacks of proper care with cerebral cortex dysfunction and autonomic nervous function has Close；Numb limbs and tense tendons, common finger, toe numbness or skin such as ant row sense, finger is dumb.Other positions of health are likely to be occurred Numb, it is also possible to paraesthesia, even hemiplegia.The middle and late stage harm infringement to blood vessel: hypertension increases the weight of whole body small artery Hardening, makes the vitals generation ischemias such as the heart, brain, kidney, anoxia, function impaired；Form atherosclerosis, easily cause blood vessel Thrombosis occurs；Also can form aneurysm, once blood pressure rises sharply, and hemangioma ruptures and is i.e. in peril of one's life.Infringement to heart: blood pressure Higher make cardiac load increase the weight of, ventricular hypertrophy easily occurs, further results in hypertensive heart disease, coronary heart disease, heart failure, the heart Rule disorder.
At present, the domestic research utilizing Chinese medicine hypertension the deepest, but to the treatment aspect of hypertension still Inadequate, people are widely used the treatment of various western medicine, and western medicine therapy blood pressure lowering is relatively rapid, but once drug withdrawal blood pressure is again Original level can be returned to, cure the symptoms, not the disease, and have certain side effect.
Summary of the invention
The invention provides a kind of Chinese medicine oral liquid treating hypertension and preparation method；Selected by Chinese medicine oral liquid of the present invention Medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and have clearing away heat and cooling blood, toxin expelling antiinflammatory, expelling wind and removing dampness it Effect, has a significant curative effect to treatment hypertension, short treating period, instant effect, and taking convenience is safe and reliable, has no side effect, controls The recurrence after healing can be avoided, treating both the principal and secondary aspects of a disease, period of taking medicine can normally work and live, and special effect is practical, and should be widely promoted application.
For achieving the above object, technical scheme is implemented as follows:
A kind of Chinese medicine oral liquid treating hypertension, it is characterised in that: make the former of described Chinese medicine oral liquid effective ingredient Material forms and parts by weight are:
Make described Chinese medicine oral liquid effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine oral liquid effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine oral liquid effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of Chinese medicine oral liquid treating hypertension, comprises the following steps that:
(1) gold lion rattan and Radix Stephaniae hemandifoliae are put into container, carry out pulverization process, grind into powder, obtain the mesh fine powder of 180, standby；
(2) Rhopilema esculenta, Herba mesonae chinensis, Folium Salicis Babylonicae, Radix Ervatamiae Hainanensis, Auricularia, Radix cocculi laurifolii, Radix Rehmanniae Preparata and salt alkali are cleaned, put into container, add Enter the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～8 times amount distilled water, Boil 2～3 hours, extract；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract；Merge three extractions Liquid, filters, obtains filtrate, standby；
(3) being placed in pot by Semen Fagopyri Esculenti, it is yellow savory spilling that intense fire is fried to surface, and taking-up cools, and puts after cooling completely Enter in container, carry out pulverization process, grind into powder, obtained the fine powder of 160 mesh, standby；
(4) Herba Artemisiae Japonicae, Herba menyanthis, Fructus Phyllanthi and Herba Spinaciae are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby With；
(5) SHANGZI is cleaned, immerse 3 times amount 50% alcohol solution dipping 1～2 hours, heating extraction 3 hours, Reclaim ethanol, filter, obtain filtrate, standby；
(6) fine powder obtained by above-mentioned steps (1)～(5), filtrate and juice are mixed, and add 10-12 times amount Distilled water, after stirring and dissolving is uniform, heated and boiled 0.5 hour, to less than 60 DEG C, stand 1 hour, filter, obtain filtrate, by filtrate Fill is sealed up for safekeeping, 121 DEG C of pressure sterilizings 20 minutes, and packaging obtains the Chinese medicine oral liquid of described treatment hypertension.
The property of medicine of Chinese medicine used by the present invention is as follows:
Gold lion rattan: bitter in the mouth, pungent, cold nature；Return liver, stomach, large intestine channel.Heat-clearing and toxic substances removing, convergence analgesia.Suffer from abdominal pain for heatstroke, Stomachache, dysentery of suffering from abdominal pain, rheumatic arthritis, venom, hypertension, skin eczema.
Rhopilema esculenta: salty in the mouth, property is put down；Return liver, kidney, lung meridian.Reduce phlegm heat, eliminating stagnation, blood pressure lowering.Cure mainly cough due to lung-heat's abundant expectoration, calentura expectorant Many comas, apoplexy accumulation and obstruction of sputum, essential hypertension, scrofula, erysipelas." medical center bun will " carries: " reinforcing the heart lung benefiting, YIN nourishing is reduced phlegm, and goes Tuberculosis, row is evil wet, and quench one's thirst relieving alcoholic intoxication, antitussive relieving restlessness.”
Herba mesonae chinensis: sweet in the mouth, light, cool in nature.Clearing away heat-damp and promoting diuresis, removing heat from blood expelling summer-heat.For acute rheumatic arthritis, hypertension, in Summer-heat, flu, jaundice, acute nephritis, diabetes.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " clearing away summer-heat.Control heatstroke, sense Emit, hypertension, muscle, arthralgia.”
Folium Salicis Babylonicae: bitter in the mouth, cold in nature；Return lung, kidney, heart channel.Heat-clearing and toxic substances removing, diuresis suppressing the hyperactive liver, pain relieving rash.Main chronic tracheitis, Urethritis, cystitis, vesical calculus, nebulousurine, hypertension, swollen ulcer drug, burn and scald, arthralgia, toothache, acute diseases such as cholera and sunstroke rash, skin scabies Itch." not Lu " carries: " treat blood in trusted subordinate, pain relieving.”
Radix Stephaniae hemandifoliae: bitter in the mouth, cold in nature；GUIXIN, liver, large intestine channel.Heat-clearing and toxic substances removing, eliminating stasis to stop pain.Main flu, pharyngalgia, diarrhoea, dysentery Disease, cellulitis toxic swelling, stomachache, wind syndrome of head pain, rheumatic arthralgia, traumatic injury.
Radix Ervatamiae Hainanensis: bitter in the mouth, pungent, cool in nature.Heat-clearing and toxic substances removing, pain relieving, blood pressure lowering.For hypertension, laryngopharynx swelling and pain, rheumatism is closed Arthralgia, stomachache, dysentery；Mastitis, furuncle and phyma, venom are controlled in external.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " removing toxic substances dissipates Knot, wind-expelling pain-stopping.Control laryngopharynx swelling and pain, mastitis, rheumatalgia, traumatic injury, cold syndrome of the stomach pain, hypertension.”
Semen Fagopyri Esculenti: sweet in the mouth, flat, cold in nature；Enter spleen, stomach, large intestine channel.Stomach invigorating, convergence, blood pressure lowering, hemostasis.It is applicable to hypertension, hair Thin nagiopasthyrosis is hemorrhage, prevents and treats apoplexy, retinal hemorrhage, pneumorrhagia；External convergence hidroschesis, antiinflammatory.
Herba Artemisiae Japonicae: bitter in the mouth, micro-sweet, cold in nature.Heat clearing away, removing heat from blood, expelling summer-heat.For cold, fever, heatstroke, malaria, pulmonary tuberculosis hectic fever, Hypertension；Wound hemorrhage, furuncle furuncle and phyma poison are controlled in external." Luchuan book on Chinese herbal medicine " carries: " wind dispelling dissipates, and induces sweat and brings down a fever.Cure cold fever of the body head Bitterly.”
SHANGZI: sweet in the mouth, puckery, property is put down.Nourish blood, hemostasis, astringing intestine to stop diarrhea, controlling nocturnal emission with astringent drugs.Cure mainly blood deficiency, spit blood, epistaxis, have blood in stool, dysentery, Proctoptosis, tinnitus, seminal emission, metrorrhagia, leukorrhagia." detailed outline is picked up any lost article from the road " carries: " nourish blood, improving eyesight.”
Auricularia: sweet in the mouth, property is put down.Enter liver,spleen,kidney three warp.Fill blood, lung moistening, hemostasis.For Qi and blood deficiency, extremity are twitched, Cough due to deficiency of the lung, spitting of blood, spit blood, epistaxis, metrorrhagia, hypertension, constipation." property of medicine cuts use " carries: " dryness moistening and intestine benefiting.”
Radix cocculi laurifolii: bitter in the mouth, pungent, cold in nature.Wind-expelling pain-stopping, inducing diuresis to remove edema, removing toxic substances, blood pressure lowering.For rheumatic arthritis, intercostal Neuralgia, acute nephritis, urinary tract infection, hypertension, rheumatic heart disease, edema；Venom is controlled in external.
Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature；Return liver, kidney channel.There is Radix Rehmanniae Preparata there is nourishing yin effect of enriching blood, can be used for blood deficiency and yellow complexion, dizzy Dizzy, palpitation and insomnia, menoxenia, the disease such as metrorrhagia, also can be used for the hectic fever hectic fever due to YIN-deficiency of deficiency of kidney yin, night sweat, seminal emission etc..
Herba menyanthis: sweet in the mouth, micro-hardship, cold in nature；GUIXIN, spleen channel.Clearing away heat and promoting diuresis, stomach invigorating, calm the nerves.For gastritis, dyspepsia, gallbladder Capsulitis, jaundice, hypertension, cardiopalmus, insomnia." the conventional Chinese herbal medicine handbook in the north " carries: " strengthening the spleen to promote digestion, tranquilizing by nourishing the heart.Control gastritis, Stomachache, dyspepsia, palpitation and insomnia, irritability.”
Fructus Phyllanthi: bitter in the mouth, sweet, sour, cool in nature；Return spleen, stomach warp.Relieving sore-throat by clearing away heat, moistening the lung and resolving phlegm, promoting the production of body fluid to quench thirst.Main flu is sent out Heat, cough, pharyngalgia, diphtheria, dysphoria with smothery sensation is thirsty, hypertension.
Salt alkali: bitter in the mouth, salty, cold in nature, nontoxic；GUIXIN, lung, kidney channel.Heart tonifying, diuresis, calm, antiinflammatory, blood pressure lowering.For gram Mountain is sick, Kaschin-Beck disease, endemic goiter, rheumatic arthritis, silicosis, hypertension." Jilin Chinese herbal medicine " carries: " heart tonifying, Calmness, aid digestion, spasmolytic is fainted, antiinflammatory.Control chronic Keshan disease, goiter, Kaschin-Beck disease, chronic gastritis, chronic nephritis, liver Inflammation, chronic bronchitis, hypertension, dermatitis, tumor.”
Herba Spinaciae: sweet in the mouth, property is put down；Return liver, stomach, large intestine, small intestine meridian.YIN nourishing suppressing the hyperactive liver, cough-relieving intestine moistening.Cure mainly hypertension, headache, Dizzy, wind-fire acute conjunctivitis, diabetes, constipation." detailed outline " carries: " promoting blood circulation, opens chest and diaphragm, and in lower controlled atmosphere, profit of quenching the thirst is quick-fried.Root is the best.”
The present invention compared with prior art, has the advantages that
Selected by Chinese medicine oral liquid of the present invention, medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has Clearing away heat and cooling blood, toxin expelling antiinflammatory, effect of expelling wind and removing dampness, have significant curative effect, short treating period, instant effect, clothes to treatment hypertension With convenient, safe and reliable, have no side effect, non-relapse after healing, treating both the principal and secondary aspects of a disease, can normally work and live, very during taking medicine Effect practicality, should be widely promoted application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine oral liquid effective ingredient of the present invention forms and weight is:
The preparation method of a kind of Chinese medicine oral liquid treating hypertension, comprises the following steps that:
(1) gold lion rattan and Radix Stephaniae hemandifoliae are put into container, carry out pulverization process, grind into powder, obtain the mesh fine powder of 180, standby；
(2) Rhopilema esculenta, Herba mesonae chinensis, Folium Salicis Babylonicae, Radix Ervatamiae Hainanensis, Auricularia, Radix cocculi laurifolii, Radix Rehmanniae Preparata and salt alkali are cleaned, put into container, add Enter the distilled water of 8～10 times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～8 times amount distilled water, Boil 2～3 hours, extract；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract；Merge three extractions Liquid, filters, obtains filtrate, standby；
(3) being placed in pot by Semen Fagopyri Esculenti, it is yellow savory spilling that intense fire is fried to surface, and taking-up cools, and puts after cooling completely Enter in container, carry out pulverization process, grind into powder, obtained the fine powder of 160 mesh, standby；
(4) Herba Artemisiae Japonicae, Herba menyanthis, Fructus Phyllanthi and Herba Spinaciae are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby With；
(5) SHANGZI is cleaned, immerse 3 times amount 50% alcohol solution dipping 1～2 hours, heating extraction 3 hours, Reclaim ethanol, filter, obtain filtrate, standby；
(6) fine powder obtained by above-mentioned steps (1)～(5), filtrate and juice are mixed, and add 10-12 times amount Distilled water, after stirring and dissolving is uniform, heated and boiled 0.5 hour, to less than 60 DEG C, stand 1 hour, filter, obtain filtrate, by filtrate Fill is sealed up for safekeeping, 121 DEG C of pressure sterilizings 20 minutes, and packaging obtains the Chinese medicine oral liquid of described treatment hypertension.
Usage and dosage: oral, every day 2 times, each 20ml, within 6 days, it is 1 course for the treatment of, can fully recover 4～6 courses for the treatment of, the state of an illness is tight Severe one is followed the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material of Chinese medicine oral liquid effective ingredient of the present invention forms and weight is:
The extract oral liquid and preparation method thereof processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 3
The raw material of Chinese medicine oral liquid effective ingredient of the present invention forms and weight is:
The extract oral liquid and preparation method thereof processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 4
The raw material of Chinese medicine oral liquid effective ingredient of the present invention forms and weight is:
The extract oral liquid and preparation method thereof processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 5
The raw material of Chinese medicine oral liquid effective ingredient of the present invention forms and weight is:
The extract oral liquid and preparation method thereof processing step of the present embodiment and usage and dosage are same as in Example 1.
Clinical data:
1, case selection:
As the Chinese medicine oral liquid for the treatment of hypertension, selecting the hyperpietic 510 example clinical observation made a definite diagnosis, patient is random It is divided into treatment group and matched group two groups, treatment group 255 example, wherein male 127 example, women 128 example, age 30～71 years old, averagely 50.5 years old age, average course of disease 8 years；Matched group 255 example, wherein male 127 example, women 128 example, age 31～70 years old, averagely 50.5 years old age, average course of disease 8 years.
Treatment group and the course of disease of two groups of cases of matched group, degrees of symptoms are basically identical, without significant difference, have comparable Property.
2, medicament selection:
Treatment group takes Chinese medicine oral liquid of the present invention, oral, every day 2 times, and each 20ml 6 days is 1 course for the treatment of, takes continuously With 4～6 courses for the treatment of, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes Propranolol, oral, a 5mg, 4 times on the one, increases by 1/4 amount, at close observation after 1～2 week Lower daily amount can be gradually increased to 100mg.
3, efficacy determination:
(1) cure: dizziness that hypertension causes, shortness of breath and palpitation, anoxia, premature beat, arrhythmia symptom all disappear, through inspection Look into body index and recover normal.
(2) effective: above-mentioned symptom substantially alleviates, body index is clearly better on inspection.
(3) effective: above-mentioned symptom has alleviated, and body index has taken a turn for the better on inspection.
(4) invalid: by above-mentioned symptom after treatment without alleviating or increasing the weight of.
4, result:
Select in the treatment group of Chinese medicine oral liquid of the present invention, cure 178 examples, effective 53 examples, effective 21 examples, invalid 3 examples, control More rate 69.8%, total effective rate 98.8%.
Matched group is cured 131 examples, effective 50 examples, effective 23 examples, invalid 51 examples, cure rate 51.4%, total effective rate 80%.
Result above shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Zhang, man, 35 years old, Spring in Pig House of Shanghai Fengxian people from district.Patient's dizziness, dim eyesight, sometimes headache, conjunctival congestion, agnogenio, patient Blood pressure is: low pressure 116mmhg, high pressure 189mmhg, and the state of an illness continues 3 years, full and large pulse, dimly red tongue, thick and greasy fur.Through taking this Bright Chinese medicine oral liquid, after taking 2 courses for the treatment of, hypertension symptom substantially alleviates, after continuing to take 2 courses for the treatment of, transference cure, blood glucose The most stable, without sense of discomfort, follow up a case by regular visits to blood pressure and raise the most again.
2, Wang, female, 49 years old, people from Handan, Hebei.Patient suffers from hypertension 5 years, blood pressure 150/110mmHg, and dizzy, the crown is sent out Fiber crops, shortness of breath and palpitation, precordialgia, arrhythmia, frequent premature beat, highly anoxia, shakiness of walking, through multiple hospitals diagnosis and treatment, Therapeutic effect is the best, introduces to our hospital through friend, takes Chinese medicine oral liquid of the present invention, and after taking 1 course for the treatment of, hypertension has Being declined, after taking 2 courses for the treatment of, hypertension transfers to normally, fully recovers after taking 4 courses for the treatment of, shortness of breath and palpitation, anoxia, premature beat, the rhythm of the heart Not normal transference cure such as grade, follows up a case by regular visits to blood pressure always normal, without recurrence after 1 year.
3, week certain, female, 39 years old, Zhenjiang, Jiangsu people.Patient's private prosecution is weak, uncomfortable liver area, and companion's dizziness mesh is swollen.Original chronic Nearly 8 years of liver history, diabetic history 3 years, history of hypertension for many years, long-term taking metformin and depressor, liver function recurrent fluctuations, once Treating in multiple hospitals, the state of an illness has no improvement, the most to our hospital, takes Chinese medicine oral liquid of the present invention treatment, takes 2 After the individual course for the treatment of, hypertension substantially controls, and after continuing to take for 3 courses for the treatment of, transference cure, blood pressure recovers normal.
4, Feng, man, 46 years old, Jinhua, Zhejiang people.Patient suffers from hypertension 3 years, blood pressure 160/100mmhg, dizzy, loses Sleep, xerostomia and numb, not polydipsia, play dysphoria with smothery sensation morning, even retch, lossless, frequent micturition, big dry stool is dilute uncomfortable, time half congealed time secret；Stringy pulse, light red tongue Red fresh and tender yellow, greasy and thin fur, takes Chinese medicine oral liquid of the present invention treatment；After taking 1 course for the treatment of, above symptom is substantially alleviated, and continues clothes After 3 courses for the treatment of, above symptom all disappears, recovery from illness, and after half a year, check is without recurrence.
5, Fu, female, 50 years old, people from Chaozhou, Guangdong.Patient suffers from hypertension nearly 7 years, used several drugs to treat, and controlled Therapeutic effect is undesirable, easily recurs；The most to our hospital, take Chinese medicine oral liquid of the present invention treatment, after taking 2 courses for the treatment of, high blood Pressure is substantially alleviated, and after continuing to take 3 courses for the treatment of, transference cure, blood pressure recovers normal.
6, beam, man, 57 years old, Sanming, Fujian Province people.Patient suffers from hypertension 11 years, blood pressure often at 180/120mmHg, normal head Dizzy, unable, nausea and vomiting, palpitation and short breath, hydrosarca, repeatedly heart failure, take multiple western medicine, therapeutic effect is the best, warp Friend introduces to our hospital, takes Chinese medicine oral liquid of the present invention treatment, after taking 2 courses for the treatment of, dizzy, unable, nausea and vomiting, Palpitation and short breath, hydrosarca symptom substantially alleviates, and after taking 4 courses for the treatment of, symptom all disappears, and blood pressure recovers normal, after 2 years with Visit without recurrence.

Claims (5)

1. the Chinese medicine oral liquid treating hypertension, it is characterised in that: make the raw material of described Chinese medicine oral liquid effective ingredient Form and parts by weight be:
Gold lion rattan 33～33～57 parts of Herba mesonae chinensiss of 57 portions of Rhopilema esculentas 32～56 parts of Folium Salicis Babylonicaves 32～56 parts
Radix Stephaniae hemandifoliae 30～54 parts of Radix Ervatamiae Hainanensiss 28～52 portions of Semen Fagopyri Esculentis 28～52 portions of Herba Artemisiae Japonicaes 27～51 parts
SHANGZI 26～26～50 portions of Radix cocculi laurifoliis of 50 portions of Auricularias 23～47 parts of Radix Rehmanniaes Preparata 22～46 parts
Herba menyanthis 22～46 parts of Fructus Phyllanthis 21～43 parts of salt alkali 20～38 portions of Herba Spinaciaes 18～35 parts.
A kind of Chinese medicine oral liquid treating hypertension the most according to claim 1, it is characterised in that: make described traditional Chinese medicine mouth Take liquid effective ingredient raw material composition and parts by weight be:
Gold lion rattan 37～37～53 parts of Herba mesonae chinensiss of 53 portions of Rhopilema esculentas 36～52 parts of Folium Salicis Babylonicaves 36～52 parts
Radix Stephaniae hemandifoliae 34～50 parts of Radix Ervatamiae Hainanensiss 32～48 portions of Semen Fagopyri Esculentis 32～48 portions of Herba Artemisiae Japonicaes 31～47 parts
SHANGZI 30～30～46 portions of Radix cocculi laurifoliis of 46 portions of Auricularias 27～43 parts of Radix Rehmanniaes Preparata 26～42 parts
Herba menyanthis 26～42 parts of Fructus Phyllanthis 25～39 parts of salt alkali 23～35 portions of Herba Spinaciaes 21～33 parts.
A kind of Chinese medicine oral liquid treating hypertension the most according to claim 1, it is characterised in that: make described traditional Chinese medicine mouth Take liquid effective ingredient raw material composition and parts by weight be:
Gold lion rattan 41～41～49 parts of Herba mesonae chinensiss of 49 portions of Rhopilema esculentas 40～48 parts of Folium Salicis Babylonicaves 40～48 parts
Radix Stephaniae hemandifoliae 38～46 parts of Radix Ervatamiae Hainanensiss 36～44 portions of Semen Fagopyri Esculentis 36～44 portions of Herba Artemisiae Japonicaes 35～43 parts
SHANGZI 34～34～42 portions of Radix cocculi laurifoliis of 42 portions of Auricularias 31～39 parts of Radix Rehmanniaes Preparata 30～38 parts
Herba menyanthis 30～38 parts of Fructus Phyllanthis 29～35 parts of salt alkali 26～32 portions of Herba Spinaciaes 24～30 parts.
A kind of Chinese medicine oral liquid treating hypertension the most according to claim 1, it is characterised in that: make described traditional Chinese medicine mouth Take liquid effective ingredient raw material composition and parts by weight be:
Gold 45 portions of Rhopilema esculentas of lion rattan, 44 parts of Folium Salicis Babylonicaves of 45 parts of Herba mesonae chinensiss 44 parts
42 parts of Radix Ervatamiae Hainanensiss of Radix Stephaniae hemandifoliae, 40 portions of Herba Artemisiae Japonicaes of 40 portions of Semen Fagopyri Esculentis 39 parts
34 parts of 38 portions of Auricularias of SHANGZI, 35 parts of Radix Rehmanniaes Preparata of 38 portions of Radix cocculi laurifoliis
34 parts of Fructus Phyllanthis of Herba menyanthis, 29 portions of Herba Spinaciaes of 32 parts of salt alkali 27 parts.
5. treating a preparation method for the Chinese medicine oral liquid of hypertension as described in any one of Claims 1 to 4, its feature exists In: comprise the following steps that:
(1) gold lion rattan and Radix Stephaniae hemandifoliae are put into container, carry out pulverization process, grind into powder, obtain the mesh fine powder of 180, standby；
(2) Rhopilema esculenta, Herba mesonae chinensis, Folium Salicis Babylonicae, Radix Ervatamiae Hainanensis, Auricularia, Radix cocculi laurifolii, Radix Rehmanniae Preparata and salt alkali are cleaned, put into container, add 8 ～10 distilled water of times amount, after soaking 5～6 hours, boil 3～4 hours, extract；Again add 6～8 times amount distilled water, boil 2～3 hours, extract；Finally, add 4～6 times amount distilled water, heated and boiled 1～2 hours, extract；Merge three extracting solution, mistake Filter, obtains filtrate, standby；
(3) being placed in pot by Semen Fagopyri Esculenti, it is yellow savory spilling that intense fire is fried to surface, and taking-up cools, and puts into appearance after cooling completely In device, carry out pulverization process, grind into powder, obtain the fine powder of 160 mesh, standby；
(4) Herba Artemisiae Japonicae, Herba menyanthis, Fructus Phyllanthi and Herba Spinaciae are cleaned, chopping, put into container, twist juice, filter impurity, stay juice standby；
(5) SHANGZI is cleaned, immerse 3 times amount 50% alcohol solution dipping 1～2 hours, heating extraction 3 hours, reclaim second Alcohol, filters, obtains filtrate, standby；
(6) fine powder obtained by above-mentioned steps (1)～(5), filtrate and juice are mixed, and add the distillation of 10-12 times amount Water, after stirring and dissolving is uniform, heated and boiled 0.5 hour, to less than 60 DEG C, stand 1 hour, filter, obtain filtrate, by filtrate fill Seal up for safekeeping, 121 DEG C of pressure sterilizings 20 minutes, packaging, obtain the Chinese medicine oral liquid of described treatment hypertension.
CN201610587159.7A 2016-07-24 2016-07-24 A kind of Chinese medicine oral liquid treating hypertension and preparation method Pending CN106109685A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103933498A (en) * 2014-03-19 2014-07-23 王泽珩 Drug for treatment of chronic atrophic gastritis and preparation method thereof
CN105381069A (en) * 2015-11-30 2016-03-09 张银环 Traditional Chinese medicine oral liquid for treating hypertension

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103933498A (en) * 2014-03-19 2014-07-23 王泽珩 Drug for treatment of chronic atrophic gastritis and preparation method thereof
CN105381069A (en) * 2015-11-30 2016-03-09 张银环 Traditional Chinese medicine oral liquid for treating hypertension

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Application publication date: 20161116