CN106106469A - A kind of containing N (cyanoalkyl) benzamide compound and the agricultural pesticide composition of isotianil - Google Patents
A kind of containing N (cyanoalkyl) benzamide compound and the agricultural pesticide composition of isotianil Download PDFInfo
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- CN106106469A CN106106469A CN201610637663.3A CN201610637663A CN106106469A CN 106106469 A CN106106469 A CN 106106469A CN 201610637663 A CN201610637663 A CN 201610637663A CN 106106469 A CN106106469 A CN 106106469A
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- isotianil
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
Abstract
The present invention relates to a kind of agricultural pesticide composition, described Pesticidal combination is made up of according to weight ratio 1:1～1:10 with isotianil N (cyanoalkyl) benzamide compound, preferably 1:2～1:6.The invention still further relates to described agricultural pesticide composition purposes in preventing and treating rice leaf roller and striped rice borer.
Description
[technical field]
The invention belongs to technical field of pesticide.More particularly it relates to an containing N-(cyanoalkyl) Benzoylamide
Compounds and the agricultural pesticide composition of isotianil, further relate to the purposes of described agricultural pesticide composition.
[background technology]
Oryza sativa L. rice leaf roller, belongs to Lepidoptera Pyralidae, and another name scrapes Kattapillar.Mainly causing harm Oryza sativa L., larva is in tillering stage, pregnant
Fringe and heading stage endanger blade, and after Oryza sativa L. is injured, mass of 1000 kernel reduces, and empty flat rate increases, and period of duration is postponed, and general underproduction 2-3 becomes,
Weight reach 5 one-tenth more than, big when occurring rice leaf a piece of withered in vain, even No kernels or seeds are gathered, as in a year of scarcity.Rice leaf roller is a kind of migratory pest,
The generation number that China occurs for 1 year is different with latitude and the temperature difference of height above sea level formation, and generation overlap, and from north, south is sent out for 1 year
Raw 1～11 generations.
Striped rice borer, belongs to Lepidoptera Pyralidae, and another name borer, borer, moth stalk worm etc., be to endanger the most on China Oryza sativa L.
One of serious Occurrence.Striped rice borer harm point evil phase Oryza sativa L., causes withered sheath and withered heart Seedling；Cause harm booting, water at heading stage
Rice, causes withered booting and dead ears；Cause harm grouting, milk stage Oryza sativa L., cause half withered fringe and insect bite strain.The general time underproduction 3%～
5%, time serious, the underproduction is more than 3 one-tenth.
N-(cyanoalkyl) benzamide compound has good prevention effect to Oryza sativa L. rice leaf roller and striped rice borer.Shen
Please numbers 201010293074.0, denomination of invention " preparation method of a kind of N-(cyanoalkyl) benzamide compound " disclose one
Plant the preparation method of N-(cyanoalkyl) benzamide compound, in its general structure I, R1Selected from H, halogen or methyl；R2It is selected from
H or halogen；R3Selected from H or C1-C6Alkyl；R4Selected from C1-C6Alkyl；Or R3And R4C is formed together with the carbon connected3-C6Ring
Alkyl；R5Selected from halogen, C1-C6Alkyl, C1-C6Alkylhalide group or C1-C6Alkyl groups in the halogenalkoxy；R6Selected from halogen；R7Selected from H, halogen, C1-
C3Alkyl, C1-C3Haloalkyl；X is selected from CH, CF, CCl or N；Y is selected from Cl or Br.This compounds have high insecticidal activity and
Bactericidal activity.
Isotianil (isotianil), No. CAS [224049-04-1], chemical name 3, the chloro-N-of 4-bis-(2-itrile group benzene
Base)-5 isothiazole formamides.Isotianil belongs to isothiazole carboxamides.Isothiazole carboxamides includes different thiophene
Bacterium amine etc. has strong plant induced activity in plant, but pathogen is not produced direct antibacterial action, but passes through
The natural immunology defense exciting crop self reaches to resist the purpose of disease.Preventative use or morbidity early application, many
Kind of biotic factor and abiotic component can the defensive Resistant reaction i.e. Systemic induction resistance of activated plant self, and affect cause of disease
Multiple links of bacterium life cycle, so that the self-protection that plant produces wide spectrum to multiple fungus, antibacterial, insecticide and virus is made
With.The chief crop that isotianil is suitable for is Oryza sativa L., is registered as preventing and treating rice blast and the antibacterial of bacterial blight of rice.
[summary of the invention]
[solving the technical problem that]
It is an object of the invention to provide a kind of containing N-(cyanoalkyl) benzamide compound and the agricultural of isotianil
Pesticidal combination.
It is a further object to provide the purposes of described agricultural pesticide composition.
[technical scheme]
The present invention is achieved through the following technical solutions.
The present invention relates to a kind of agricultural pesticide composition, described agricultural pesticide composition is by having following chemical structural formula
(I) compound forms according to weight ratio 1:1～1:10 with isotianil:
A preferred embodiment of the invention, chemical constitution formula (I) compound with the weight ratio of isotianil is
1:2～1:6.
The present invention relates to a kind of agricultural fungicides, described agricultural fungicides contains by weight described in 0.5～95.0%
Agricultural pesticide composition and surplus be acceptable carrier and auxiliary agent on pesticide.
A preferred embodiment of the invention, described agricultural fungicides contains by weight described in 2～80%
Agricultural pesticide composition and surplus be acceptable carrier and auxiliary agent on pesticide.
A preferred embodiment of the invention, described agricultural fungicides contains by weight described in 5～70%
Agricultural pesticide composition and surplus be acceptable carrier and auxiliary agent on pesticide.
According to a kind of detailed description of the invention of the present invention, the dosage form of described agricultural fungicides is water dispersible granules, suspension
Agent, wettable powder, microemulsion or aqueous emulsion.
The invention still further relates to described agricultural pesticide composition or described agricultural fungicides at preventing and treating Oryza sativa L. cnaphalocrocis
Purposes in snout moth's larva and striped rice borer.
The present invention will be described in detail belows.
The present invention relates to a kind of agricultural pesticide composition, described agricultural pesticide composition is by having following chemical structural formula
(I) compound forms according to weight ratio 1:1～1:10 with isotianil:
This compound is equivalent to previously mentioned Chinese patent application CN201010293074.0, invention entitled " one
The preparation method of N-(cyanoalkyl) benzamide compound " disclosed in No. 18 compound, wherein R1=Cl, R2=Cl, R3
=CH3、R4=CH3、R5=Br, R6=Cl, R7=H and X=N (for simplicity, represents with 419).Its chemical bromo-1-of entitled 3-
(3-chloropyridine-2-base)-N-[the chloro-6-of 2,4-bis-(2-cyanopropyl-2-base formamido) phenyl]-1H-pyrazoles-5-formyl
Amine.It is prepared by the method described according to above-mentioned patent application CN201010293074.0.
In agricultural pesticide composition of the present invention, when the amount of isotianil is in described scope, if the amount of 419 exceedes
The scope of described amount, then can be high because of consumption, and safety declines, and poisoning easily occurs.
When the amount of 419 is in described scope, if the amount of isotianil exceedes the scope of described amount, also can be because of consumption
Height, safety declines, poisoning easily occurs.
Therefore, in agricultural pesticide composition of the present invention, 419 with the weight ratio of isotianil be 1:1～1:10 be reasonable
's.
Preferably, 419 is 1:2～1:6 with the weight ratio of isotianil.
The present invention relates to a kind of agricultural fungicides.Described agricultural fungicides contains by weight described in 0.5～95.0%
Agricultural pesticide composition and surplus be acceptable carrier and auxiliary agent on pesticide.
In the present invention, described carrier or auxiliary agent are it should be understood that be used for improving medicine in Pesticide formulation or use
Agent physicochemical property, improves drug effect, it is simple to the auxiliary substances of the transport performances such as storage, such as wetting agent, emulsifying agent, dispersant,
Sticker, stabilizer or synergist etc..According to the present invention, every have these performances and not appoint agricultural fungicides of the present invention
The chemical substance of what negative effect may be used to the present invention, and they are all within protection scope of the present invention.
According to the present invention, if the agricultural pesticide composition content of described agricultural fungicides is less than 0.5%, then can be because having
Effect composition is low, is unfavorable for the manufacturing of product from economic angle；If the agricultural pesticide composition of described agricultural fungicides
When content is higher than 95.0%, then can be unfavorable for the performance of drug effect because content is the highest and be easily generated poisoning；Therefore, described agricultural insecticidal
The agricultural pesticide composition content of agent is 0.5～95.0% to be appropriate.
Preferably, described agricultural fungicides contains agricultural pesticide composition described in 2～70% by weight, more preferably
Ground agricultural pesticide composition described in 10～80%, and surplus is acceptable carrier and auxiliary agent on pesticide.
According to the present invention, on pesticide acceptable auxiliary agent be one or more be selected from emulsifying agent, wetting agent, dispersant,
The auxiliary agent of thickening agent, antifreezing agent, disintegrating agent, binding agent, defoamer or filler.These auxiliary agents are conducive to stable effective ingredients,
And give full play to its drug effect.
According to method known in those skilled in the art, Pesticidal combination of the present invention can be joined when reality is applied
Making the dosage form agriculturally allowed, preferable dosage form is water dispersible granules, suspending agent, wettable powder, microemulsion or aqueous emulsion.
For water dispersible granules, those skilled in the art are very familiar with using corresponding auxiliary agent to complete the present invention.Dispersion
Agent is selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate；Wetting agent is selected from polyoxyethylene alcohol, alkyl sulfate, alkane
Base sulfonate, naphthalene sulfonate；Disintegrating agent is selected from ammonium sulfate, carbamide, sucrose, glucose, aluminum chloride, citric acid, succinic acid, carbonic acid
Hydrogen sodium；Binding agent is selected from kieselguhr, corn starch, PVA, carboxymethyl (ethyl) cellulose and microcrystalline Cellulose class；Filler is selected from
Kieselguhr, Kaolin, white carbon, fine particle calcium carbonate, meerschaum, Pulvis Talci, attapulgite, potter's clay etc..
To suspending agent, spendable auxiliary agent has: dispersant selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate,
TERSPERSE 2425 (Huntsman Corporation of the U.S. produces, alkyl naphthalene sulfonic acid salt)；Emulsifying agent selected from Nongru-700 # (common name:
Alkyl phenol formaldehyde resin polyoxyethylene ether), agriculture breast 2201, this dish-60# (common name: sorbitan monostearate), emulsifying agent
T-60 (common name: sorbitan monostearate polyoxyethylene ether), agriculture breast 1601# (common name: phenethyl phenol polyoxy second
Alkene polyethenoxy ether), TERSPERSE 4894 (Huntsman Corporation of U.S. product), FS3000 (phosphate type anionic surface live
Property agent)；Wetting agent is selected from alkylphenol-polyethenoxy poly-base ether formaldehyde condensation products sulfate, alkylphenol-polyethenoxy base ether phosphoric acid
Ester, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE 2500
(Huntsman Corporation of U.S. product), SXC (sulfonic acid type anion surfactant)；Thickening agent is selected from xanthan gum, polyvinyl alcohol, silicon
Acid magnalium, bentonite；Preservative is selected from benzoic acid, sodium benzoate, BIT (1,2-benzisothiazole-3-ketone)；Defoamer is for having
Machine silicon class defoamer；Antifreezing agent is selected from ethylene glycol, propylene glycol, glycerol, carbamide.
To wettable powder, spendable auxiliary agent has: dispersant is selected from polycarboxylate, lignosulfonates, alkylnaphthalene sulphur
Hydrochlorate；Wetting agent is selected from alkyl sulfate, alkylsulfonate, naphthalene sulfonate；Filler is selected from ammonium sulfate, carbamide, sucrose, Fructus Vitis viniferae
Sugar, kieselguhr, Kaolin, white carbon, fine particle calcium carbonate, Pulvis Talci, attapulgite, potter's clay etc..
To microemulsion, spendable auxiliary agent has: emulsifying agent is selected from calcium dodecyl benzene sulfonate (agriculture breast 500#), agriculture breast
700#, agriculture breast 2201#, this dish-60#, tween 80-60#, TX-10, agriculture breast 1601, agriculture breast 600#, agriculture breast 400#；Cosolvent selects
From methanol, isopropanol, n-butyl alcohol, ethanol；Solvent is selected from Ketohexamethylene, N-Methyl pyrrolidone, dimethylbenzene, toluene, solvent naphtha (board
Number: S-150, S-180, S-200)；Stabilizer is selected from triphenyl phosphite, epoxychloropropane.
To aqueous emulsion, spendable auxiliary agent has: emulsifying agent is selected from NPE (EO=10) phosphate ester, triphen
Ethyl-phenol polyoxyethylene ether phosphate (agriculture breast 600# phosphate ester), Nongru-700 #, agriculture breast 2201#, Span-60#, emulsifying agent T-
60, TX-10, agriculture breast 1601#, agriculture breast 600#, agriculture breast 400#；Solvent selected from dimethylbenzene, toluene, Ketohexamethylene, solvent naphtha (trade mark:
S-150、S-180、S-200)；Stabilizer is selected from triphenyl phosphite, epoxychloropropane, acetic anhydride；Antifreezing agent selected from ethylene glycol, third
Glycol, glycerol, carbamide, inorganic salts such as sodium chloride；Thickening agent is selected from xanthan gum, polyvinyl alcohol, bentonite, aluminium-magnesium silicate；Anti-
Rotten agent is selected from benzoic acid, sodium benzoate.
Bactericidal composition of the present invention can provide with finished product preparation form, and i.e. in compositions, each material has mixed
Close；Can also provide with unit dose preparation, directly mix in bucket (tank) before using.The concentrate of the present invention generally mixes with water
Concentration to required active substance.
The invention still further relates to described agricultural insecticidal composite or described agricultural insecticide preventing and treating Oryza sativa L. rice leaf roller and
Purposes in striped rice borer.
Pesticidal combination of the present invention and insecticide can use conventional method to use, such as, spray, spray.Its amount of application can
To change according to weather conditions or crop growthing state, can use before or after pest damage occurs.Protective effect
The content of persistent period generally compound individualized with compositions relevant, also relevant to extraneous factor, such as weather, but pass through
Use suitable dosage form can slow down the impact of weather.
Pesticidal combination of the present invention and insecticide can also have weeding with other, the compound of bactericidal property mixes makes
With, it is also possible to it is used in mixed way with nematicide, protective agent, growth regulator, nutrient for plants or soil conditioner.
[beneficial effect]
Pesticidal combination of the present invention has a following beneficial effect:
1,419 to compound isotianil good to rice leaf roller and striped rice borer prevention effect, solves 419 independent medications pair
Water rice hopper is double controls the problem that effect is poor, can reach Oryza sativa L. rice leaf roller, striped rice borer, the most double effect controlled of plant hopper；
2, reduce times for spraying, lower drug cost, reduce environmental pollution and pesticide residues；
3, compositions is made up of the effective ingredient of different mechanism of action, and action site increases, and is conducive to overcoming and delay evil
The drug-fast generation of worm.The present composition is equal without obvious harmful effect to trial crops, and leaf color, growing way etc. are all normal, safety
Property is good, meets the security requirement of pesticidal preparations.
[detailed description of the invention]
Below in conjunction with embodiment, the present invention will be further described, but is not limited to embodiment.
In the present invention, if no special instructions, " % " is all weight percentage, and ": " or " ratio " is weight ratio.
One, the preparation of agricultural fungicides of the present invention
1, water dispersible granules is prepared
Embodiment 1: prepare 66%419 isotianil water dispersible granules (effective ingredient 1:10)
Weigh in terms of this pesticide water dispersible granule gross weight 6% chemical constitution formula (I) 419,60% isotianil, 2%
Naphtholsulfonic acid formaldehyde condensation products, 1%N-methyl-oleoyl-sodium taurocholate, 1% soluble starch and the kaolinite being supplemented to 100%
Soil.By formula proportion, by former medicine and the mix homogeneously such as auxiliary agent, filler, after comminution by gas stream, obtain powder, add a certain amount of water
Mixing, carries out pelletize in comminutor, is then dried, sieves and i.e. obtain granular product.
Embodiment 2: prepare 56%419 isotianil water dispersion granules (effective ingredient 1:3)
Weigh in terms of this insecticide water dispersion granule gross weight 14% chemical constitution formula (I) 419,42% isotianil,
3% naphtholsulfonic acid formaldehyde condensation products, 4%N-methyl-oleoyl-sodium taurocholate, 3% soluble starch, 2% sodium sulfate are with supplementary
To the Kaolin of 100%.By formula proportion, by former medicine and the mix homogeneously such as auxiliary agent, filler, after comminution by gas stream, obtain powder,
Add the mixing of a certain amount of water, comminutor carries out pelletize, be then dried, sieve and i.e. obtain granular product.
2, suspending agent is prepared
Embodiment 3: prepare 48%419 isotianil suspending agents (effective ingredient 1:3)
Weigh in terms of this insecticide suspending agent gross weight 12% chemical constitution formula (I) 419,36% isotianil, 3%
TERSPERSE 4894,3.5%SXC (sulfonic acid type anion surfactant), 0.1% xanthan gum, 1% aluminium-magnesium silicate, 5% second
Glycol, 0.03%BIT (1,2-benzisothiazole-3-ketone), (Evonik Degussa Corp. goes out 0.5% organic silicon defoamer TA32H
Product), deionized water adds to 100%.By formula proportion, with water as medium, former medicine, dispersant, suspending agent and antifreezing agent etc. are added
Enter in high-shear emulsion machine shearing 30min, then with after sand mill sand milling, obtain suspending agent.
Embodiment 4: prepare 45%419 isotianil suspending agents (effective ingredient 1:2)
Weigh in terms of this insecticide suspending agent gross weight 15% chemical constitution formula (I) 419,30% isotianil, 3%
FS3000 (phosphate type anion surfactant), 1.5%SXC (sulfonic acid type anion surfactant), 0.25% xanthan
Glue, 0.5% aluminium-magnesium silicate, 5% ethylene glycol, 0.03%BIT (1,2-benzisothiazole-3-ketone), 0.3% organic silicon defoamer
TA32H (Evonik Degussa Corp.'s product), deionized water adds to 100%.By formula proportion, with water as medium, by former medicine, dispersion
Agent, suspending agent and antifreezing agent etc. join shearing 30min in high-shear emulsion machine, then with after sand mill sand milling, obtain suspending agent.
3, wettable powder is prepared
Embodiment 5: prepare 56%419 isotianil wettable powders (effective ingredient 1:6)
Weigh in terms of this insecticide wettable powder gross weight 8% chemical constitution formula (I) 419,48% isotianil, 2%
Sodium lauryl sulphate, 5% White Carbon black, 10% sodium lignin sulfonate and the precipitated calcium carbonate being supplemented to 100%.Want by formula
Ask, after various auxiliary agents, filler, former medicine are mixed after Roughpulverizer is pulverized, enter jet mill and be fully pulverized and mixed prepared
Wettable powder.
Embodiment 6: prepare 70%419 isotianil wettable powders (effective ingredient 2:5)
Weigh in terms of this insecticide wettable powder gross weight 20% chemical constitution formula (I) 419,50% isotianil, 2%
Sodium lauryl sulphate, 5% naphthalene sulfonic acid-formaldehyde condensation product, 4% sodium lignin sulfonate, 6% White Carbon black be supplemented to 100% light
Matter calcium carbonate.By recipe requirements, after various auxiliary agents, filler, former medicine being mixed after Roughpulverizer is pulverized, enter jet mill
Fully it is pulverized and mixed prepared wettable powder.
4, microemulsion is prepared
Embodiment 7: prepare 20%419 isotianil microemulsions (effective ingredient 1:4)
Weigh in terms of this insecticide microemulsion gross weight 4% chemical constitution formula (I) 419,16% isotianil, 5% agriculture breast
700#, 2% agriculture breast 500#, 2% agriculture breast 1601#, 15% cyclohexanone, 15%N-methyl pyrrolidone, through dissolving completely and mixing
Uniformly, deionized water adds to 100%, after stirring, obtains product.
Embodiment 8: prepare 30%419 isotianil microemulsions (effective ingredient 1:5)
Weigh in terms of this insecticide microemulsion gross weight 5% chemical constitution formula (I) 419,25% isotianil, 6% agriculture breast
700#, 3% agriculture breast 500#, 5% this dish-60#, 20% toluene, 10%N-methyl pyrrolidone, through dissolving completely and mixing all
Even, deionized water adds to 100%, after stirring, obtains product.
5, aqueous emulsion is prepared
Embodiment 9: prepare 45%419 isotianil aqueous emulsions (effective ingredient 1:8)
Weigh in terms of this insecticide aqueous emulsion gross weight 5% chemical constitution formula (I) 419,40% isotianil, 5% agriculture breast
2201#, 4% NPE (EO=10) phosphate ester, 3% agriculture breast 600#, 1% epoxychloropropane, 20% dimethylbenzene,
15% Ketohexamethylene, mixed dissolution obtains oil phase.5% ethylene glycol, 0.1% xanthan gum, 0.03%BIT (1,2-benzisothiazole-
3-ketone), deionized water add to 100%, be made into aqueous phase.Oil phase addition aqueous phase is sufficiently mixed, after high-shear emulsifying, is produced
Product.
Embodiment 10: prepare 40%419 isotianil aqueous emulsions (effective ingredient 1:4)
Weigh in terms of this insecticide aqueous emulsion gross weight 8% chemical constitution formula (I) 419,32% isotianil, 3% agriculture breast
1601,2% NPE (EO=10) phosphate ester, 3% agriculture breast 600#, 2%Span-60#, 1% epoxychloropropane,
20% dimethylbenzene, 20% Ketohexamethylene, mixed dissolution obtains oil phase.5% ethylene glycol, 0.1% xanthan gum, 0.03%BIT (1,2-benzene
And isothiazoline-3-ketone), deionized water add to 100%, be made into aqueous phase.Oil phase addition aqueous phase is sufficiently mixed, through high shear breast
After change, obtain product.
6, granule is prepared
Embodiment 11: prepare 11%419 isotianil granules (effective ingredient 1:10)
Weigh in terms of this insecticide granule agent gross weight 1% chemical constitution formula (I) 419,10% isotianil, 2% naphthols
Sulfonic formaldehyde condensation compound, 1%N-methyl-oleoyl-sodium taurocholate, 1% xanthan gum and the Kaolin being supplemented to 100%.By joining
Side's ratio, by former medicine and the mix homogeneously such as auxiliary agent, filler, obtains powder after comminution by gas stream, adds the mixing of a certain amount of water,
Comminutor carries out pelletize, is then dried, sieves and i.e. obtain granular product.
Embodiment 12: prepare 4%419 isotianil granules (effective ingredient 1:3)
Weigh in terms of this insecticide granule agent gross weight 1% chemical constitution formula (I) 419,3% isotianil, 3% naphthols sulphur
Acid formaldehyde condensation products, 4%N-methyl-oleoyl-sodium taurocholate, 3% soluble starch, 2% xanthan gum be supplemented to 100%
Kaolin.By formula proportion, by former medicine and the mix homogeneously such as auxiliary agent, filler, after comminution by gas stream, obtain powder, add a certain amount of
Water mixing, comminutor carries out pelletize, is then dried, sieves and i.e. obtain granular product.
Two, BIOLOGICAL ACTIVITY EXAMPLES
BIOLOGICAL ACTIVITY EXAMPLES is divided into indoor biological activity Example and land for growing field crops BIOLOGICAL ACTIVITY EXAMPLES.
Toxicity Determination to Oryza sativa L. rice leaf roller after activity Example 1:419 and isotianil are compounding
In order to further appreciate that the virulence of 419 and isotianil compositions, carry out a large amount of formulation screening test.
Pesticidal combination biological activity determination of the present invention is as follows:
According to pesticide indoor bioassay test rule (agricultural industry criteria NY/T1154.2-2006), in addition
Improvement, measures single dose LC50With mixture LC50。
Select indoor throughout the year with rice seedling raising worm kind (27 DEG C, 14h illumination/d).Select indoor feeding 3 age, size one
The rice leaf roller larvae caused is for experiment.Use stomach toxicity method.Beat with the card punch of diameter 1cm and take leaf dish, leaf dish is immersed medicine
After liquid 5～10s, suck unnecessary medicinal liquid with filter paper, put into culture dish, and note moisturizing, go to put into enough leaf dish by examination worm
Raising in culture dish, test sets the corresponding organic solvent without medicament and is processed as comparison, often processes and is repeated 4 times, often repeats to put worm
10～15, check result after 24h, touch polypide with brush pen, reactionless be considered as dead worm.Add up each borer population alive processed with total
Borer population, calculates the mortality rate of each process and corrected mortality (Abbott ' s formula)；Special with " DPS data handling system " V14.50
Industry version carries out data analysis statistical, obtains regression straight line, LC50Value.Toxicity index is calculated by the abundant method of Sun Yun (Sun etc., 1960), by
Following formula is calculated co-toxicity coefficient:
Toxicity index × the A of theoretical mixed toxicity index (TTI)=A content (%) in mixed
Toxicity index × the B of+B content (%) in mixed
When co-toxicity coefficient is more than 120, show that this mixture has potentiation；And co-toxicity coefficient less than 80 time, show
This mixture has antagonism；And co-toxicity coefficient more than 80 less than 120 time, show that this mixture has summation action.
419 see table 1 with isotianil different ratio mixture to the Toxicity Determination result of rice leaf roller.
Table 1:419 Toxicity Determination result to rice leaf roller compounding with isotianil
From above-mentioned Toxicity Determination result it can be seen that 419 with isotianil in the range of weight ratio 1:1～1:10
Time compounding, its co-toxicity coefficient (CTC) is all higher than 120, illustrates that Oryza sativa L. rice leaf roller is had significantly by 419 with isotianil mixture
Potentiation.
2, Toxicity Determination to striped rice borer after activity Example 2:419 and isotianil are compounding
Pesticidal combination biological activity determination of the present invention is as follows:
According to pesticide indoor bioassay test rule (agricultural industry criteria NY/T1154.2-2006 and agricultural
Industry standard NY/T1154.7-2006), and improved, measure single dose LC50With mixture LC50。
Select indoor throughout the year with rice seedling raising worm kind (27 DEG C, 14h illumination/d).Select indoor feeding low age, size
Consistent striped rice borer nymph is for experiment.Use stomach toxicity method.Beat with the card punch of diameter 1cm and take leaf dish, leaf dish is immersed medicinal liquid 5
～after 10s, suck unnecessary medicinal liquid with filter paper, put into culture dish, and note moisturizing, examination worm is gone to put into the cultivation of enough leaf dish
Raising in ware, test sets the corresponding organic solvent without medicament and is processed as comparison, often processes and is repeated 4 times, often repeat to put worm 10～
15, check result after 24h, touch polypide with brush pen, reactionless be considered as dead worm.Add up each borer population alive processed and total worm
Number, calculates the mortality rate of each process and corrected mortality (Abbott ' s formula)；By " DPS data handling system " V14.50 specialty
Version carries out data analysis statistical, obtains regression straight line, LC50Value.With the abundant method of Sun Yun (Sun etc., 1960) calculate toxicity index, by under
State formula and be calculated co-toxicity coefficient:
Toxicity index × the A of theoretical mixed toxicity index (TTI)=A content (%) in mixed
Toxicity index × the B of+B content (%) in mixed
When co-toxicity coefficient is more than 120, show that this mixture has potentiation；And co-toxicity coefficient less than 80 time, show
This mixture has antagonism；And co-toxicity coefficient more than 80 less than 120 time, show that this mixture has summation action.
419 see table 2 with isotianil different ratio mixture to the Toxicity Determination result of striped rice borer.
Table 2:419 Toxicity Determination result to striped rice borer compounding with isotianil
From above-mentioned Toxicity Determination result it can be seen that 419 with isotianil in the range of weight ratio 1:1～1:10
Time compounding, its co-toxicity coefficient (CTC) is all higher than 120, illustrates that 419 have significant potentiation work with isotianil mixture to striped rice borer
With.
3, activity Example 3: preventing and treating rice leaf roller field control effectiveness test
According to medicine inspecting institute of the Ministry of Agriculture " GB-T 17980.4-2000 pesticide field efficacy medicine test criterion (one) insecticide
Preventing and treating rice leaf roller " regulation carry out test.
Test method: paddy rice rice leaf roller low instar larvae peak period dispenser is once.
Formulation rate is 750kg/hm2, plant blade face even spraying.Plot area 25m2, repeating for 4 times, random district group arranges.
Every experimental plot 10 samplings of parallel jump method, investigate 2 clumps at every, and investigation 20 clumps, investigates the borer population alive of every 2 clumps altogether.
According to survey result, calculate Revision insect recluced rate and preventive effect according to formula below (1) with (2).Test data uses Deng
Ken Shi duncan's new multiple range method (DMRT) carries out statistical analysis.
Result of the test is listed in table 3 below.
Oryza sativa L. rice leaf roller field control effectiveness test result prevented and treated by table 3
From above-mentioned field control effectiveness test result it can be seen that 419 compounding with isotianil after can effectively prevent and treat the vertical volume of rice
Leaf snout moth's larva, preventive effect is better than compareing medicament.To trial crops safety in scope of medication.
4, activity Example 4: preventing and treating striped rice borer field control effectiveness test
According to medicine inspecting institute of the Ministry of Agriculture " GB-T 17980.1-2000 pesticide field efficacy medicine test criterion (one) insecticide
Preventing and treating Oryza sativa L. Lepidoptera borer pest " regulation carry out test.
Test method: striped rice borer hatching Sheng phase beginning in rice field is to the dispenser of hatching peak phase once.
Formulation rate is 750kg/hm2, plant blade face even spraying.Plot area 25m2, repeating for 4 times, random district group arranges.
Every experimental plot 10 samplings of parallel jump method, investigate 2 clumps at every, and investigation 20 clumps, investigates the borer population alive of every 2 clumps altogether.
According to survey result, calculate Revision insect recluced rate and preventive effect according to formula below (1) with (2).Test data uses Deng
Ken Shi duncan's new multiple range method (DMRT) carries out statistical analysis.
Test of pesticide effectiveness result is listed in table 4 below.
Striped rice borer field control effectiveness test result prevented and treated by table 4
From above-mentioned field control effectiveness test result it can be seen that 419 compounding with isotianil after can effectively prevent and treat striped rice borer,
Preventive effect is better than compareing medicament.To trial crops safety in scope of medication.
In sum, under indoor biometrics and field control effectiveness test result show that agricultural pesticide composition of the present invention has
State beneficial effect:
1, compared with single dose, this Pesticidal combination has significant potentiation to preventing and treating rice leaf roller and striped rice borer, prolongs
Grow the lasting period, improve effect；
2, reduce times for spraying, lower drug cost, reduce environmental pollution and pesticide residues；
3, compositions is made up of the effective ingredient of different mechanism of action, and action site increases, and is conducive to overcoming and delay evil
The drug-fast generation of worm.The present composition is equal without obvious harmful effect to trial crops, and leaf color, growing way etc. are all normal, safety
Property is good, meets the security requirement of pesticidal preparations.
Pesticidal combination of the present invention has good preventive effect to Oryza sativa L. rice leaf roller and striped rice borer.
Claims (7)
1. an agricultural pesticide composition, it is characterised in that described agricultural pesticide composition is by having following chemical constitution formula (I)
Compound and isotianil form according to weight ratio 1:1～1:10:
Agricultural pesticide composition the most according to claim 1, it is characterised in that chemical constitution formula (I) compound and different thiophene bacterium
The weight ratio of amine is 1:2～1:6.
3. an agricultural fungicides, it is characterised in that it contains 0.5～95.0% agriculture described in claim 1 or 2 by weight
Industry Pesticidal combination and surplus are acceptable carrier and auxiliary agent on pesticide.
Agricultural fungicides the most according to claim 3, it is characterised in that it contains by weight 2～80% claim 1
Or agricultural pesticide composition and the surplus described in 2 is acceptable carrier and auxiliary agent on pesticide.
Agricultural fungicides the most according to claim 3, it is characterised in that it contains by weight 5～70% claim 1
Or agricultural pesticide composition and the surplus described in 2 is acceptable carrier and auxiliary agent on pesticide.
6. according to the agricultural fungicides described in claim any one of claim 3-5, it is characterised in that its dosage form is moisture
Shot agent, suspending agent, wettable powder, microemulsion, aqueous emulsion or granule.
Agricultural pesticide composition the most according to claim 1 and 2 or according to claim institute any one of claim 3-7
The agricultural fungicides stated purposes in preventing and treating Oryza sativa L. rice leaf roller and striped rice borer.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008134969A1 (en) * | 2007-04-30 | 2008-11-13 | Sinochem Corporation | Benzamide compounds and applications thereof |
| CN101516196A (en) * | 2006-09-18 | 2009-08-26 | 巴斯夫欧洲公司 | Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide |
| CN101896064A (en) * | 2007-12-11 | 2010-11-24 | 拜尔农作物科学股份公司 | Active compound combinations |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101516196A (en) * | 2006-09-18 | 2009-08-26 | 巴斯夫欧洲公司 | Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide |
| WO2008134969A1 (en) * | 2007-04-30 | 2008-11-13 | Sinochem Corporation | Benzamide compounds and applications thereof |
| CN101896064A (en) * | 2007-12-11 | 2010-11-24 | 拜尔农作物科学股份公司 | Active compound combinations |
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Application publication date: 20161116 |