CN106074281A - A kind of preparation method and applications of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution - Google Patents

A kind of preparation method and applications of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution Download PDF

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Publication number
CN106074281A
CN106074281A CN201610550229.1A CN201610550229A CN106074281A CN 106074281 A CN106074281 A CN 106074281A CN 201610550229 A CN201610550229 A CN 201610550229A CN 106074281 A CN106074281 A CN 106074281A
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Prior art keywords
pers
bull
hericium erinaceus
extracting solution
eye cream
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CN201610550229.1A
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Chinese (zh)
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不公告发明人
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Foshan Jucheng Biochemical Technology Research and Development Co Ltd
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Guangzhou Danqi Daily Chemical Co Ltd
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Priority to CN201610550229.1A priority Critical patent/CN106074281A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses the preparation method and applications of a kind of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution, the preparation method of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution comprises the steps: that Hericium erinaceus (Bull. Ex Fr.) Pers. is crushed to 32 mesh or 35 mesh after removing impurity, the ethanol solution of addition 85% is as Extraction solvent, solid-liquid ratio is 1:5, Extracting temperature is 65 DEG C, ultrasonic extraction 40min.This Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution is applied in cosmetics, can play good crease-resistant, anti-aging effects, it is possible to firm skin, reduces microgroove, adds in eye cream, it is possible to quickly eliminate wrinkle near the eyes, keeps skin beauty water profit flexible.

Description

A kind of preparation method and applications of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution
Technical field
The present invention relates to cosmetic field, particularly relate to the preparation method and applications of a kind of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution.
Background technology
Hericium erinaceus (Bull. Ex Fr.) Pers. (latin name: Hericium erinaceus (Rull ex F.) Pers.), cry again Hericium erinaceus (Bull. Ex Fr.) Pers., monkey mushroom, Hericium erinaceus, Pilus Caprae seu Ovis bacterium, hedgehog hydnum, Rrinaceus earopaeus bacterium, hedgehog bacterium, monkey mushroom etc., belong to fungus, and its edible history has 3,000 years, and nutritional labeling is rich Richness, belongs to gourmet food ancient times, but to the domestication of wild Hedgehogt and promotes artificial culture due to the mankind now, market is supplied Hericium erinaceus (Bull. Ex Fr.) Pers. increase, it has also become the famous dish of normal food on people's dining table.Hericium erinaceus (Bull. Ex Fr.) Pers. contains plurality of active ingredients, predominantly polysaccharide, low Polysaccharide, sterol, fatty acid, erinacine, Hericium erinaceus (Bull. Ex Fr.) Pers. Ketone etc., have liver-protecting and stomach-protecting, blood sugar lowering, protection is neural, strengthen human body exempts from The effects such as epidemic disease power, anticancer, antioxidation.Wherein, the polysaccharide in Hericium erinaceus (Bull. Ex Fr.) Pers., polyphenol compound have significant anti-aging effects, Add in cosmetics, it is possible to removing wrinkle and resisting aging is old.
Chinese invention patent application number 201310725414.6, invention entitled " a kind of low stimulation eye cream " discloses one Eye cream, this eye cream includes following parts by weight ingredient: nonionic surfactant 15-20 part, alkyl polyglucoside 10-20 part, sarcosine Receive 5-10 part, bisabolol 0.1-0.6 part, natural oil 1.2-2.5 part, wetting agent 2.0-3.0 part, antioxidant 1.0-1.2 part, Thickening suspending agent 1.0-1.5 part, triethanolamine 1.5-2.0 part, skin protection silicone oil 1.0-2.0 part, remaining is distilled water.Although this eye Frost is non-stimulated to skin, but it contains silicone oil component, and the time that eye cream rests on skin is the longest, therefore life-time service Hair follicle can be blocked, and this eye cream can only reduce the generation of microgroove, can not wrinkle reduction, for the many people's effect of microgroove near the eyes not Greatly.
Chinese invention patent application 201410210095.X, invention entitled " a kind of eye cream and preparation method thereof " is open A kind of eye cream, the effective ingredient of this eye cream is made up of the component of following weight portion: Flos Camelliae Japonicae quintessence oil 3-5 part, Herba Salviae Japonicae essential oil 3-5 part, Semen Armeniacae Amarum quintessence oil 5-10 part, Fructus Citri Limoniae juice 15-20 part, Radix Dauci Sativae juice 15-20 part, vitamin C 3-5 part, Mel 5-8 part, glycerol 10-15 part, Fructus Lycopersici esculenti juice 5-8 part and water 10-15 part.The Herba Salviae Japonicae essential oil of one of the effective ingredient of this eye cream, containing estrogen, pregnant Woman and personage's age of sucking prohibit the use of, because it can stimulate the menstrual flow and move back breast, it is also possible to cause hysterospasm.Fructus Citri Limoniae in effective ingredient Juice then belongs to photosensitive material, uses daytime and speckle can even occurs because of its absorption effects but skin darkening.And Fructus Citri Limoniae skin protection It is generally suitable for oily skin, dry skin or sensitive skin then unsuitable multiplex so that it uses crowd restricted.Fructus Lycopersici esculenti juice Although there being whitening antioxidation effect, but the organic acid such as its malic acid contained, citric acid make its acidity higher, to skin spinosity Swash property, spread upon the mucosa on Diazolidinyl Urea top layer on the face.Although Mel can neutralize, still but sensitive or skin that cutin is thin not Can directly smear.
Eye cream, belongs to one of skin type cosmetic product, has moist effect, can lower black eye, eye pouch problem, it is also possible to Improve wrinkle, microgroove.Functionally dividing, eye cream can be divided into moist eye cream, consolidation eye cream, aging resistance eye cream, antiallergic eye cream etc.. Hericium erinaceus (Bull. Ex Fr.) Pers. is the delicacy from mountain on people's dining table the most always, and it takes orally has multiple efficacies, but outward in cosmetics not There is research.Therefore, its external is worth and has huge development prospect.Especially its removing wrinkle and resisting aging acts on always, and it is in eye cream Application prospect is the most considerable.
Summary of the invention
The present invention, by substantial amounts of experimentation, finds that Hericium erinaceus (Bull. Ex Fr.) Pers. external also has obvious anti-aging effects, adds to In cosmetics, it is possible to removing wrinkle and resisting aging is old, firm skin.
The concrete technical scheme of the present invention is as follows:
This preparation method providing a kind of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution, described preparation method comprises the steps: Hericium erinaceus (Bull. Ex Fr.) Pers. Being crushed to 32 mesh or 35 mesh after removing impurity, the ethanol solution of addition 85% is as Extraction solvent, and solid-liquid ratio is 1:5, extracts Temperature is 65 DEG C, ultrasonic extraction 40min.
The present invention is investigated its application in cosmetics of the Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution according to above-mentioned preparation method gained, Mainly Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution application in crease-resistant, anti-aging cosmetics.
Application in cosmetics, the content of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution is 5-30%.
Present invention also offers a kind of anti-wrinkle eye cream, described eye cream includes the raw material of following weight percentage ratio:
Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution: 5-30%,
Avenabeta glucosan: 1-4%,
Trehalose: 2-4%,
Hyaluronic acid: 0.15-0.75%,
Cetearyl alcohol: 1-2.5%,
Hydrogenated jojoba oil: 1.5-3.5%,
Tremella extract: 1-3%,
Soil melon root extract: 3-5%,
Stereth-2:2-3.2%,
Xanthan gum: 1-2.5%,
Tert-butyl group hydrogen-based methoxybenzene: 0.02-0.05%,
Phenoxyethanol: 0.1-0.3%,
Deionized water: surplus.
Further, described eye cream is made up of the raw material of following weight percentage ratio:
Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution: 15%,
Avenabeta glucosan: 2%,
Trehalose: 3%,
Hyaluronic acid: 0.5%,
Cetearyl alcohol: 1.8%,
Hydrogenated jojoba oil: 2.8%,
Tremella extract: 2.5%,
Soil melon root extract: 4%,
Stereth-2:2.4%,
Xanthan gum: 2.5%,
Tert-butyl group hydrogen-based methoxybenzene: 0.03%,
Phenoxyethanol: 0.2%,
Deionized water: surplus.
Advantages of the present invention and having the beneficial effect that:
(1) the Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution of the present invention uses natural plant raw material Hericium erinaceus (Bull. Ex Fr.) Pers., wide material sources, is suitable for extensive raw Produce;
(2) preparation method of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution of the present invention, its effective ingredient dissolution rate is high, and preparation technology is simple;
(3) application of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution of the present invention, is applied in cosmetics to play good crease-resistant, defying age effect Really, quickly eliminate wrinkle near the eyes, keep skin beauty water profit flexible, and its composition is safe, non-stimulated, have no side effect.
Detailed description of the invention
In order to make those skilled in the art be more fully understood that technical scheme, below in conjunction with embodiment to this Bright technical scheme is described in further detail.
Embodiment 1-5, comparative example 1
Table 1 embodiment 1-5, the eye cream composition of comparative example 1
Embodiment 6 efficacy assessments is tested
The eye cream preparing embodiment 1-5 and comparative example 1 carries out efficacy assessments test, chooses and has obvious microgroove near the eyes Women 80, is randomly divided into 8 groups, and experimental group 1-5 uses the eye cream that embodiment 1-5 prepares respectively, and matched group 1 uses comparative example 1 The eye cream prepared, matched group 2 uses commercially available eye cream, blank group not to use any product.Using method: morning and evening every day face cleaning After eye cream is spread upon near the eyes, be massaged into gently its absorb, continuous use is observed after two months and makes an appraisal.Table 2 is eye cream Eliminate microgroove effect assessment table near the eyes.
Table 2 eye cream eliminates microgroove effect assessment table near the eyes
Microgroove: 0=does not has effect to microgroove;1=microgroove has improvement;2=microgroove is completely eliminated;
As can be known from the results of Table 2, the eye cream that embodiment 1-5 prepares all has good effect eliminating microgroove, uses two Substantially microgroove near the eyes can be dispelled completely after Yue.Not containing Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution in comparative example, it dispels the effect of microgroove near the eyes The eye cream prepared well below embodiment 1-5, this explanation, Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution is applied in eye cream, it is possible to play good dispelling Effect of wrinkle defying age.Knowable to the experimental result of commercially available eye cream, being added with the eye cream of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution, its elimination is the thinnest Effect of stricture of vagina is better than general commercially available eye cream.
Embodiment 7 safety evaluatio is tested
1. test method
(1) test specimen: the eye cream that embodiment 1-5 prepares;
(2) experimental animal: test select 20 health, skin unabroken regular grade white rabbit, body weight be 2kg~ 3kg, male and female half and half, Female rabbits unpregnancy is for producing son;Animal House temperature is 20~25 DEG C, and relative humidity is 50~60%;
(3) test procedure: rabbit is randomly divided into 5 groups, often group 4, male and female half and half, by family's rabbit back spinal column both sides before test Hair cut, unhairing scope is respectively 3cm × 3cm, takes each test specimen 0.5ml respectively and is applied on the skin of side, opposite side skin Skin smears equivalent distilled water, smears every day once, smears 14 days continuously.Second day starts, and smears front cropping every time, uses distilled water Remove residual tested material, viewing test district and check plot after 1 hour, scoring record.
2, result of the test
Test scores is carried out with reference to " cosmetics health specification " (version in 2007) " skin irritation/corrosivity " standards of grading Scoring, the safety evaluatio result of the test of the eye cream that embodiment 1 prepares is shown in Table 3.
The safety evaluatio of the eye cream that table 3 embodiment 1 prepares
The integral mean value of this table is 0~< 0.5 to represent nonirritant, and 0.5~< 2.0 represents subexcite, 2.0~< 6.0 represent moderate stimulation, and 6.0~8.0 represent strong and stimulating.
As can be seen from result of Table 3, the eye cream that embodiment 1 prepares is to no skin irritation;The eye cream that embodiment 2-5 prepares The scoring of safety evaluatio result of the test is identical with table 3.As can be seen here, Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution is applied in cosmetics to skin not Produce zest, gentle pro-skin.
Embodiment described above only have expressed the several embodiments of the present invention, and it describes more concrete and detailed, but also Therefore the restriction to the scope of the claims of the present invention can not be interpreted as.It should be pointed out that, for those of ordinary skill in the art For, without departing from the inventive concept of the premise, it is also possible to make some deformation and improvement, these broadly fall into the guarantor of the present invention Protect scope.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.

Claims (5)

1. the application in preparation has the cosmetics of crease-resistant, senile-resistant efficacy of the Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution, described Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution Preparation method comprises the steps: that Hericium erinaceus (Bull. Ex Fr.) Pers. is crushed to 32 mesh or 35 mesh after removing impurity, and the ethanol solution adding 85% is made For Extraction solvent, solid-liquid ratio is 1:5, and Extracting temperature is 65 DEG C, ultrasonic extraction 40min.
Application the most according to claim 1, it is characterised in that in described cosmetics, the content of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution is 5- 30%.
Application the most according to claim 1 and 2, it is characterised in that described cosmetics are eye cream.
Application the most according to claim 3, it is characterised in that described eye cream includes the raw material of following weight percentage ratio:
The Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution that preparation method prepares as claimed in claim 1: 5-30%,
Avenabeta glucosan: 1-4%,
Trehalose: 2-4%,
Hyaluronic acid: 0.15-0.75%,
Cetearyl alcohol: 1-2.5%,
Hydrogenated jojoba oil: 1.5-3.5%,
Tremella extract: 1-3%,
Soil melon root extract: 3-5%,
Stereth-2:2-3.2%,
Xanthan gum: 1-2.5%,
Tert-butyl group hydrogen-based methoxybenzene: 0.02-0.05%,
Phenoxyethanol: 0.1-0.3%,
Deionized water: surplus.
Eye cream the most according to claim 4, it is characterised in that described eye cream includes the raw material of following weight percentage ratio:
The Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution that preparation method prepares as claimed in claim 1: 15%,
Avenabeta glucosan: 2%,
Trehalose: 3%,
Hyaluronic acid: 0.5%,
Cetearyl alcohol: 1.8%,
Hydrogenated jojoba oil: 2.8%,
Tremella extract: 2.5%,
Soil melon root extract: 4%,
Stereth-2:2.4%,
Xanthan gum: 2.5%,
Tert-butyl group hydrogen-based methoxybenzene: 0.03%,
Phenoxyethanol: 0.2%,
Deionized water: surplus.
CN201610550229.1A 2016-07-12 2016-07-12 A kind of preparation method and applications of Hericium erinaceus (Bull. Ex Fr.) Pers. extracting solution Pending CN106074281A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109875933A (en) * 2019-03-28 2019-06-14 广州市富宝日用化工有限公司 Compact eye cream cosmetics of a kind of U.S. pupil and preparation method thereof
CN110693922A (en) * 2019-11-22 2020-01-17 福建拓天生物科技有限公司 Hericium erinaceus spore powder wall breaking process

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Publication number Priority date Publication date Assignee Title
CN104758198A (en) * 2014-01-08 2015-07-08 南京美纯生物科技有限公司 Powerful antioxidant skin-care product containing blackberry extract and preparation method and application thereof
CN105030624A (en) * 2015-09-17 2015-11-11 福建绿宝食品集团有限公司 Mushroom hand cream and preparation method thereof
CN105232439A (en) * 2015-10-11 2016-01-13 庄健峰 Moisturizing skin care product and preparation method thereof
CN105434205A (en) * 2014-11-08 2016-03-30 马南行 Composition for quickly smoothening eye wrinkles and delaying senescence and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758198A (en) * 2014-01-08 2015-07-08 南京美纯生物科技有限公司 Powerful antioxidant skin-care product containing blackberry extract and preparation method and application thereof
CN105434205A (en) * 2014-11-08 2016-03-30 马南行 Composition for quickly smoothening eye wrinkles and delaying senescence and preparation method thereof
CN105030624A (en) * 2015-09-17 2015-11-11 福建绿宝食品集团有限公司 Mushroom hand cream and preparation method thereof
CN105232439A (en) * 2015-10-11 2016-01-13 庄健峰 Moisturizing skin care product and preparation method thereof

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* Cited by examiner, † Cited by third party
Title
吴美媛: "猴头菇不同活性部位体外抗氧化活性研究", 《食品研究与开发》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109875933A (en) * 2019-03-28 2019-06-14 广州市富宝日用化工有限公司 Compact eye cream cosmetics of a kind of U.S. pupil and preparation method thereof
CN110693922A (en) * 2019-11-22 2020-01-17 福建拓天生物科技有限公司 Hericium erinaceus spore powder wall breaking process
CN110693922B (en) * 2019-11-22 2022-01-14 福建拓天生物科技有限公司 Hericium erinaceus spore powder wall breaking process

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