CN106036916A - Postoperative repairing nutriment - Google Patents
Postoperative repairing nutriment Download PDFInfo
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- CN106036916A CN106036916A CN201610388248.9A CN201610388248A CN106036916A CN 106036916 A CN106036916 A CN 106036916A CN 201610388248 A CN201610388248 A CN 201610388248A CN 106036916 A CN106036916 A CN 106036916A
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Abstract
The invention discloses a postoperative repairing nutriment. The postoperative repairing nutriment is prepared from the following components in parts by weight: 52-78 parts of composite collagen peptide powder, 12-28 parts of haematococcus pluvialis sweets, 12-28 parts of oxycoccos sweets, and 12-28 parts of beta-glucan sweets. The postoperative repairing nutriment provided by the invention is a nutriment for rehabilitation in accordance with postoperative patients, and can strengthen the constitutions, improve immunity, and comprehensively provide nutrient substances required for postoperative repair.
Description
Technical field
The present invention relates to nutraceutical field, be specifically related to a kind of postoperative reparation nutriment.
Background technology
Collagen peptide is collagen or gelatin is made after treatment, has the higher property digested and assimilated, collagen peptide
The formation of bone can be promoted, strengthen the ossein structure under low calcium level, pre-anti-osteoporosis；Collagen peptide has protection stomach
Mucosa and antiulcer action, anti-allergic effects etc..In skin, collagen protein accounts for 70%, constitutes a fine and closely woven bullet in skin
Power net, pins moisture, supports skin.Therefore, timely replenishing collagen, for improving skin problem, slow down aging, have non-
The best effect.
Haematocoocus Pluvialls (Haematococcus pluvialis), is called again the raw Haematococcus Pluvialis in lake or lake hemopoietic ball algae, is
A kind of chlorella generally existed, belongs to volvocales, Haematococcus Pluvialis section.Currently, sky is produced during Haematocoocus Pluvialls is acknowledged as nature
So astaxanthin is best biological.Astaxanthin is a kind of Red carotenoids, and its anti-oxidation function is 500 times of vitamin E.Shrimp
Blue or green element has the effects such as protection skin and eyes, opposing radiation, cardiovascular Aging, senile dementia and cancer.Haematococcus Pluvialis extract
Special molecular configuration, can pass through human body cell outer wall, the oxygen-derived free radicals in direct scavenger cell, strengthen cell regeneration energy
Power, maintains function of human body balance and reduces the accumulation of senile cell, and protection cell and DNA are healthy from inside to outside.In sum, open
The Haematocoocus Pluvialls sending out natural is the astaxanthin of carrier, is one of effective means ensureing human intake's safety.
Cranberry, formal name used at school: Oxycoccos, also someone cries mossberry, cranberry, belongs to Ericaceae Vaccinium Fructus Mume
Estrade subgenus, some areas in North America are widely cultivated at present, the most relatively common in the Daxinganling District of China.
Beta glucan is the polysaccharide that a class is widely present in antibacterial, fungus, algae and plant, its main source it
One is saccharomyces cerevisiae (Saccharomyces cerevisisae).
The invention provides a kind of postoperative reparation nutriment, for postoperative patient, there is important repair.
Summary of the invention
For above-mentioned deficiency present in prior art, the technical problem to be solved is to provide a kind of postoperative repair
Multiple nutriment.
The present invention seeks to be achieved through the following technical solutions:
A kind of postoperative reparation nutriment, including the component of following weight portion: composite collagen Gly-His-Lys 52-78 part, red ball
Algae confectionary sheet 12-28 part, cranberry confectionary sheet 12-28 part, beta glucan confectionary sheet 12-28 part.
Described composite collagen Gly-His-Lys, is made up of the raw material of following weight parts: collagen protein Gly-His-Lys 58-62 part, sugarcane
Really trisaccharide 2-8 part, casein hydrolysate peptides 8-12 part, Fructus Lycii 12-18 part, composite enzyme 8-12 part, adjuvant 1-5 part, antistaling agent
0.01-1 part.
Described Haematococcus Pluvialis confectionary sheet, is made up of the raw material of following weight parts: haematococcus pluvialis powder 48-52 part, compound ammonia
Base acid chelating calcium 18-22 part, Pulvis Talci 0.5-5 part, microcrystalline Cellulose 0.5-5 part, maltodextrin 3-13 part, adjuvant 18-22 part.
Described cranberry confectionary sheet, is made up of the raw material of following weight parts: cranberry powder 88-92 part, Pulvis Talci 0.5-5
Part, microcrystalline Cellulose 0.5-5 part, maltodextrin 5-10 part, adjuvant 18-22 part.
Described beta glucan confectionary sheet, is made up of the raw material of following weight parts: Folium Kaki concentrates powder 45-55 part, β-Portugal gathers
Sugar 18-22 part, Pulvis Talci 0.5-5 part, microcrystalline Cellulose 0.5-5 part, maltodextrin 5-10 part, adjuvant 18-22 part.
Preferably, described composite collagen Gly-His-Lys, Haematococcus Pluvialis confectionary sheet, cranberry confectionary sheet, beta glucan confectionary sheet
In adjuvant by xylotriose, shell six sugar, cottonseed sugar mix, described xylotriose, shell six sugar, the mass ratio of cottonseed sugar be
(1-3): (1-3): (1-3).
Preferably, the described antistaling agent described in antistaling agent is the one in 4',5,7-trihydroxyflavone, dihydroquercetin, soybean isoflavone
Or multiple mixture.
Preferably, described collagen protein Gly-His-Lys can be morrhua collagen protein Gly-His-Lys, is specifically referred to application number:
201310064690.2 in prepared by method shown in detailed description of the invention.
Preferably, described casein hydrolysate peptides can be alkalescence casein antioxidant peptide dry powder, is specifically referred to Shen
Please number: in 201510672835.6 prepared by method shown in detailed description of the invention.
Preferably, described Fructus Lycii is Fructus Lycii powder, is specifically referred to application number: in 201110075273.9 embodiment 2
Method prepare.
Preferably, described composite enzyme is ferment powder, is specifically referred to application number: implement in 201510571336.8
Prepared by the method for example 1.
Preferably, described haematococcus pluvialis powder is obtained by Haematocoocus Pluvialls drying, pulverizing.
Preferably, described compound amino acid chelate calcium, it is referred to number of patent application: concrete in 201010210090.9
Shown in embodiment prepared by method.
Preferably, described cranberry powder is obtained by cranberry drying, pulverizing.
Preferably, described Folium Kaki concentrates powder, with reference to number of patent application: detailed description of the invention in 200810140214.3
Prepared by shown method.
Preferably, described beta glucan is yeast beta-dextran, can prepare or be commercially available, it is also possible to reference to patent
Application number: in 200910038724.4, shown in detailed description of the invention prepared by method.
The postoperative reparation nutriment that the present invention provides, is specific to the nutriment of rehabilitation of patients after surgical treatment, it is possible to reinforcement
Matter, improves immunity, provides the nutrient substance required for postoperative reparation in all directions.
Detailed description of the invention
Each raw material introduction in embodiment:
Collagen protein Gly-His-Lys is morrhua collagen protein Gly-His-Lys, with reference to application number: in 201310064690.2 the side of embodiment 1
Prepared by method.
Casein hydrolysate peptides is alkalescence casein antioxidant peptide dry powder, with reference to application number: implement in 201510672835.6
Prepared by the method for example 2.
Fructus Lycii is Fructus Lycii powder, with reference to application number: in 201110075273.9 prepared by the method for embodiment 2.
Composite enzyme is ferment powder, with reference to application number: in 201510571336.8 prepared by the method for embodiment 1.
Soybean isoflavone, No. CAS: 574-12-9.
Xylotriose, No. CAS: 47592-59-6.
Ketose, No. CAS: 470-69-9.
Cottonseed sugar, No. CAS: 512-69-6.
Shell six sugar, No. CAS: 41708-95-6.
Compound amino acid chelate calcium, with reference to number of patent application: method system shown in specific embodiment 1 in 201010210090.9
Standby.
Pulvis Talci, No. CAS: 14807-96-6, use Shanghai, river, Shanghai Fengxian branch company of titanium white heavy chemicals company limited to carry
1250 mesh food grade talc powder of confession.
Microcrystalline Cellulose, No. CAS: 9004-34-6, the food stage using Henan Qi Nuo food ingredient company limited to provide is micro-
Crystalline cellulose.
Maltodextrin, No. CAS: 9050-36-6, use Zouping dextrin branch company of Shandong Xiwang Sugar Co., Ltd to provide
Food stage maltodextrin.
Haematocoocus Pluvialls, use Yunnan cloud gold can the Haematocoocus Pluvialls that provides of Bioisystech Co., Ltd, moisture
For 52wt%.
Cranberry powder, uses the cranberry from northern US import.
Yeast beta-dextran, with reference to number of patent application: in 200810140214.3 prepared by method shown in embodiment 1.
Folium Kaki concentrates powder, with reference to number of patent application: in 200810140214.3 prepared by method shown in embodiment 1.Folium Kaki by
Bozhou City often rich Pharmaceutical sells company limited to be provided.
Embodiment 1
Postoperative reparation nutriment, including the component of following weight portion: composite collagen Gly-His-Lys 60 parts, Haematococcus Pluvialis confectionary sheet
20 parts, cranberry confectionary sheet 20 parts, beta glucan confectionary sheet 20 parts.
Composite collagen peptide powder raw material (weight portion): collagen protein Gly-His-Lys 60 parts, ketose 6 parts, casein hydrolysis
Peptide 10 parts, Fructus Lycii 14 parts, composite enzyme 10 parts, adjuvant 2.1 parts, soybean isoflavone 0.03 part.
Haematococcus Pluvialis confectionary sheet raw material (weight portion): Haematocoocus Pluvialls 50 parts, compound amino acid chelate calcium 20 parts, Pulvis Talci 1
Part, microcrystalline Cellulose 1 part, maltodextrin 10 parts, adjuvant 21 parts.
Cranberry confectionary sheet raw material (weight portion): 88 parts of cranberry powder, Pulvis Talci 1 part, microcrystalline Cellulose 1 part, Fructus Hordei Germinatus are stuck with paste
Essence 10 parts, adjuvant 21 parts.
Beta glucan confectionary sheet raw material (weight portion): Folium Kaki concentrate 50 parts of powder, yeast beta-dextran 20 parts, Pulvis Talci 1 part,
Microcrystalline Cellulose 1 part, maltodextrin 10 parts, adjuvant 21 parts.
Described adjuvant is uniformly mixed for 1:1:1 is in mass ratio obtained by xylotriose, shell six sugar, cottonseed sugar.
Postoperative reparation nutriment preparation method, comprises the following steps:
(1) prepared by composite collagen Gly-His-Lys: by collagen protein Gly-His-Lys, ketose, casein hydrolysate peptides, Fructus Lycii, answer
It is ground to 120 mesh after closing ferment, adjuvant, soybean isoflavone mix homogeneously, obtains composite collagen Gly-His-Lys.
(2) prepared by Haematococcus Pluvialis confectionary sheet:
A, Haematocoocus Pluvialls is placed in the baking oven of 50 DEG C and is dried 6 hours, dried Haematocoocus Pluvialls is crushed to 120
Mesh, obtains haematococcus pluvialis powder；
B, compound amino acid chelate calcium, adjuvant are crushed to 120 mesh respectively；
C, maltodextrin is uniformly mixed for 1:2 in mass ratio with water, obtains maltodextrin slurry；
D, by haematococcus pluvialis powder, pulverize after adjuvant and microcrystalline Cellulose, compound amino acid chelate calcium stirring mix equal
Even；Add maltodextrin slurry stirring, stir agglomerating to hold, the soft material i.e. dissipated pressed, pelletize with 16 mesh sieves, obtain wet
Grain；
E, wet granular is placed in 50 DEG C of drying baker be dried 12 hours, with 20 mesh sieve granulate, obtain dry granule；
F, by dry granule addition Pulvis Talci fully mix, tabletting makes confectionary sheet, every tablet quality 600mg.Obtain embodiment 1
Haematococcus Pluvialis confectionary sheet.
(3) prepared by cranberry confectionary sheet:
A, cranberry is placed in the baking oven of 50 DEG C and is dried 6 hours；By dried cranberry enucleation, it is crushed to 120 mesh,
Obtain cranberry powder；
B, ingredient powder is broken to 120 mesh；
C, maltodextrin is uniformly mixed for 1:2 in mass ratio with water, obtains maltodextrin slurry；
D, by cranberry powder, pulverize after adjuvant be uniformly mixed with microcrystalline Cellulose；Add maltodextrin slurry to stir
Mix, stir agglomerating to hold, the soft material i.e. dissipated pressed, pelletize with 16 mesh sieves, obtain wet granular；
E, wet granular is placed in 50 DEG C of drying baker be dried 12 hours, with 20 mesh sieve granulate, obtain dry granule；
F, by dry granule addition Pulvis Talci fully mix, tabletting makes confectionary sheet, every tablet quality 600mg.Obtain embodiment 1
Cranberry confectionary sheet
(4) prepared by beta glucan confectionary sheet:
A, yeast beta-dextran, adjuvant are crushed to 120 mesh respectively；
B, maltodextrin is uniformly mixed for 1:2 in mass ratio with water, obtains maltodextrin slurry；
C, Folium Kaki is concentrated powder, pulverize after adjuvant be uniformly mixed with microcrystalline Cellulose, yeast beta-dextran；Add again
Enter maltodextrin slurry stirring, stir agglomerating to hold, the soft material i.e. dissipated pressed, pelletize with 16 mesh sieves, obtain wet granular；
D, wet granular is placed in 50 DEG C of drying baker be dried 12 hours, with 20 mesh sieve granulate, obtain dry granule；
E, by dry granule addition Pulvis Talci fully mix, tabletting makes confectionary sheet, every tablet quality 600mg.Obtain embodiment 1
Rich in ascorbic beta glucan confectionary sheet.
Embodiment 2
Substantially the same manner as Example 1, differ only in: described adjuvant is 1:1 by shell six sugar, cottonseed sugar in mass ratio
It is uniformly mixed and obtains.Obtain the postoperative reparation nutriment of embodiment 2.
Embodiment 3
Substantially the same manner as Example 1, differ only in: described adjuvant is 1:1 in mass ratio by xylotriose, cottonseed sugar
It is uniformly mixed and obtains.Obtain the postoperative reparation nutriment of embodiment 3.
Embodiment 4
Substantially the same manner as Example 1, differ only in: described adjuvant is 1:1 in mass ratio by xylotriose, shell six sugar
It is uniformly mixed and obtains.Obtain the postoperative reparation nutriment of embodiment 4.
Test case 1
Postoperative reparation nutriment embodiment 1-4 prepared, is placed in 25 DEG C, preservation half a year under relative humidity 85% environment,
" GB/T 4789.2-2010 microbiological test of food hygiene total plate count mensuration " is used to carry out total plate count test.Concrete survey
Test result is shown in Table 1.
Table 1: postoperative reparation nutriment total plate count test list position: cfu/g
Inventor is found surprisingly that, comparing embodiment 1 and embodiment 2-4, embodiment 1 (xylotriose, shell six sugar, cottonseed sugar
Compounding) antiseptic property is apparently higher than embodiment 2-4 (in xylotriose, shell six sugar, cottonseed sugar, any two kinds compound).
Test case 2
The Haematococcus Pluvialis confectionary sheet preparing embodiment 1-4 carries out stability test.
The astaxanthin comprised in Haematococcus Pluvialis confectionary sheet of the present invention is the index composition of Haematocoocus Pluvialls.By embodiment 1-4
The Haematococcus Pluvialis confectionary sheet prepared uses aluminum-plastic composite membrane bag hermetic package respectively, places 3 months at a temperature of they are placed in 38 DEG C, surveys
In fixed each sample, astaxanthin during March is relative to residual content during this sample 0 month.Blue or green with ultraviolet-uisible spectrophotometer prawn
Element standard solution is scanned in the range of 400-600nm, determines a length of 480nm of its maximum absorption wave.Survey at 480nm respectively
Determine the absorbance of the astaxanthin standard solution of variable concentrations, obtain standard curve.Standard curve equation is y=0.0227x-
0.0098, and R2=0.9997, linear good at 0-50mg/L wide standards curve of astaxanthin concentration is described.
Concrete outcome is shown in Table 2.
Table 2: stability test result table
| Astaxanthin residual content % | |
| Embodiment 1 | 99.2 |
| Embodiment 2 | 93.6 |
| Embodiment 3 | 94.2 |
| Embodiment 4 | 93.8 |
Comparing embodiment 1 and embodiment 2-4, embodiment 1 (xylotriose, shell six sugar, cottonseed sugar compound) stability is the most excellent
In embodiment 2-4 (in xylotriose, shell six sugar, cottonseed sugar, any two kinds compound).
Test case 3
The beta glucan confectionary sheet preparing embodiment 1-4 carries out stability test.
The vitamin C comprised in beta glucan confectionary sheet of the present invention is the index composition of Malpighia glabra L. powder.By embodiment
The beta glucan confectionary sheet that 1-4 prepares uses aluminum-plastic composite membrane bag hermetic package respectively, places 3 at a temperature of they are placed in 38 DEG C
Month, vitamin C when measuring March in each sample is relative to residual content during this sample 0 month.Use reversed-phase high-performance liquid chromatography
Method measures, DiamonsilTM C18 chromatographic column (4.6mm × 250mm, 5 μm), and flowing for methanol-0.1% phosphoric acid (5:95) is mutually
Flowing phase, flow velocity 1mL min-1, column temperature 25 DEG C, detection wavelength is 242nm.
Concrete outcome is shown in Table 3.
Table 3: stability test result table
| Vitamin C residual content, % | |
| Embodiment 1 | 98.9 |
| Embodiment 2 | 94.2 |
| Embodiment 3 | 93.6 |
| Embodiment 4 | 93.9 |
Comparing embodiment 1 and embodiment 2-4, embodiment 1 (xylotriose, shell six sugar, cottonseed sugar compound) stability is the most excellent
In embodiment 2-4 (in xylotriose, shell six sugar, cottonseed sugar, any two kinds compound).
Test case 4
Postoperative reparation nutriment to embodiment 1 preparation, carries out post-operative recovery measure of merit.
Object: 50 fracture surgery rehabilitations.
Test object point in morning every day 9, at 5 in afternoon drink for twice, often organize the compound adhesive using embodiment 1-4 to prepare respectively
Former protein peptide powder 3 grams, takes the water that 300mL temperature is 45 DEG C and brews, take simultaneously Haematococcus Pluvialis confectionary sheet, cranberry confectionary sheet, β-
Glucosan confectionary sheet is each a piece of, continuous 2 weeks.
Result: subjects postoperative wound heals, and energy and antisecosis, wound is without cicatrix, effective percentage 100%.
It is demonstrated experimentally that the postoperative reparation nutriment of the present invention can effective enhancing immunity, postoperative reparation is provided in all directions
Required protein, vitamin, trace element, promote that human body recovers.
Claims (5)
1. a postoperative reparation nutriment, it is characterised in that include the component of following weight portion: composite collagen Gly-His-Lys 52-
78 parts, Haematococcus Pluvialis confectionary sheet 12-28 part, cranberry confectionary sheet 12-28 part, beta glucan confectionary sheet 12-28 part.
Postoperative reparation nutriment the most as claimed in claim 1, it is characterised in that: described composite collagen Gly-His-Lys, by under
The raw material stating weight portion forms: collagen protein Gly-His-Lys 58-62 part, ketose 2-8 part, casein hydrolysate peptides 8-12 part, Fructus Lycii
12-18 part, composite enzyme 8-12 part, adjuvant 1-5 part, antistaling agent 0.01-1 part；
Described antistaling agent is one or more mixture in 4',5,7-trihydroxyflavone, dihydroquercetin, soybean isoflavone.
Described adjuvant is mixed by xylotriose, shell six sugar, cottonseed sugar, described xylotriose, shell six sugar, the mass ratio of cottonseed sugar
For (1-3): (1-3): (1-3).
Postoperative reparation nutriment the most as claimed in claim 1, it is characterised in that: described Haematococcus Pluvialis confectionary sheet, by following heavy
The raw material composition of amount part: haematococcus pluvialis powder 48-52 part, compound amino acid chelate calcium 18-22 part, Pulvis Talci 0.5-5 part, crystallite
Cellulose 0.5-5 part, maltodextrin 3-13 part, adjuvant 18-22 part；
Described adjuvant is mixed by xylotriose, shell six sugar, cottonseed sugar, described xylotriose, shell six sugar, the mass ratio of cottonseed sugar
For (1-3): (1-3): (1-3).
Postoperative reparation nutriment the most as claimed in claim 1, it is characterised in that: described cranberry confectionary sheet, by following heavy
The raw material composition of amount part: cranberry powder 88-92 part, Pulvis Talci 0.5-5 part, microcrystalline Cellulose 0.5-5 part, maltodextrin 5-10
Part, adjuvant 18-22 part；
Described adjuvant is mixed by xylotriose, shell six sugar, cottonseed sugar, described xylotriose, shell six sugar, the mass ratio of cottonseed sugar
For (1-3): (1-3): (1-3).
Postoperative reparation nutriment the most as claimed in claim 1, it is characterised in that: described beta glucan confectionary sheet, by following
The raw material composition of weight portion: Folium Kaki concentrates powder 45-55 part, beta glucan 18-22 part, Pulvis Talci 0.5-5 part, microcrystalline Cellulose
0.5-5 part, maltodextrin 5-10 part, adjuvant 18-22 part；
Described adjuvant is mixed by xylotriose, shell six sugar, cottonseed sugar, described xylotriose, shell six sugar, the mass ratio of cottonseed sugar
For (1-3): (1-3): (1-3).
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| CN104605353A (en) * | 2015-01-27 | 2015-05-13 | 南阳市新天地生物科技有限公司 | Formula food suitable for being eaten by tumor patients after operation and preparation method of formula food |
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Application publication date: 20161026 |