CN102813113B - Composition capable of regulating human flora and immune function - Google Patents
Composition capable of regulating human flora and immune function Download PDFInfo
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- CN102813113B CN102813113B CN201210278247.0A CN201210278247A CN102813113B CN 102813113 B CN102813113 B CN 102813113B CN 201210278247 A CN201210278247 A CN 201210278247A CN 102813113 B CN102813113 B CN 102813113B
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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Abstract
The invention relates to a healthcare product, in particular to a composition capable of regulating human flora and immune function and a preparation method of the composition. The composition capable of regulating human flora and immune function comprises one of dried vegetable and fruit plant powder or water extract of the vegetable and fruit, fried dried coarse grain powder or the water extract of the coarse grain, and fruit juice together with natural active polysaccharide, propolis, etc. The composition provided by the invention is capable of regulating the imbalance of human flora and reinforcing human immune function, and has functions of regulating intestine and stomach, promoting gastrointestinal motility, dredging qi, protecting stomach membrane, relieving alcoholism and protecting digestive system well. A product containing the composition provided by the invention is capable of preventing and treating dental ulcer, and plays a helping role in treating gingival bleeding, halitosis or gastric acid and stomachache.
Description
Technical field
The present invention relates to a kind of health products, be specifically related to a kind of composition its preparation method that can regulate human body flora and immunologic function.
Background technology
Immunity is the defense mechanism of human body self, is human body identification and any foreign matter (virus, bacterium etc.) of eliminating external intrusion; Process old and feeble, disease, self cell of damage, dead, sex change and the ability of identification and processing vivo mutations cell and virus infected cell.Modern immunology thinks, immunity is human body identification and the physiological reaction of getting rid of " dissident ".
Cause that the reason that immunity reduces has a lot, as 1. dog-eat-dog, work, learning pressure is large; 2. life, work rhythm is fast, nervous; 3. dietary structure changes; 4. partial eclipse, dietary unbalance; 5. lack motion etc.In recent years, people are in office, and the time that computer is sat is above oversize, think little of motion and make disease of digestive tract incidence of disease rising, cause constipation, gastric ulcer, hydrochloric acid in gastric juice, even fat etc. being on the rise, it is exactly liable to illness that hypoimmunity the most directly shows.Because of often ill, increase the weight of the consumption of body, so generally have a delicate constitution, malnutritive, aphthae; Easily constipation, the performances such as hydrochloric acid in gastric juice, One's spirits are drooping, fatigue and weak, appetite reduction, sleep-disorder, sick, have an injection and take medicine the normal potluck that just gets married.Each sickly all will could recover for a long time, and usually outbreak repeatedly.If things go on like this can cause health and intelligence development bad, also easily bring out major disease.Underlying causes is that hypoimmunity or immunity are unsound.When immune function of human body imbalance, or immune system is when unsound, and stomach or gastral flora change; Through scientific experiment and clinical discovery, harmful bacteria in human body (as this bacterium of Weir etc.) surpasses beneficial bacterium (as Bifidobacterium etc.) causes intestinal bacilli illness, causes constipation, diarrhoea and immunocompromised.Together with two kinds of diseases of intestines problem and hypoimmunity interweave, cause intestines disorder, can not normally play a role, thereby cause many complication, as hypoimmunity, intestinal cancer, breast cancer, diabetes, hypertension, high fat of blood etc.Intestines problem harm is large, relates to crowd wide, is one of fiendish killer in modern disease today.
Immunity and human body flora population are closely related, and except mental element, the various materials that body immunity and human body are taken in body are closely related.It is generally acknowledged, the material that strengthens immunity has several classes below: one. protein, and protein is the basic element that forms human body cell, same is also the main component that forms white blood cell and antibody; If health famine protein, can impel lymphocytic quantity to reduce, cause immunity function degradation, therefore the food of many picked-up high proteins, for example: fresh meat, the chicken and duck flesh of fish, eggs, cow's milk and dairy products, abundant animal protein, the globulin including can help you to improve immunity.Two. the integrality of vitamin A vitamin A and cell is relevant, can help cell to anti-oxidant, the A if health is deficient in vitamin, can make the volume-diminished of thymus gland and spleen, the vigor of relative cell also can be along with reduction, therefore absorb enough vitamin As, just can promote the vigor of immunocyte, improve the quantity of immunocyte.Three. vitamin C vitamin C has the effect of Promote immunity system, and increase the ability that white corpuscles engulf bacteria, and enhancing thymus gland and lymphocytic ability, help human body to increase the content of interferon in opposing content and lifting blood, it is effective polyphenoils, can resist destructive molecule, one of vitamin strengthening immunity, be full of ascorbic vegetables, fruit (for example: apple, lemon, orange etc.) be all the good food source that promotes immunity, four. the jinx that vitamin E vitamin E is free radical, also can produce by enhancing antibody simultaneously, from resisting viral viewpoint, there is antioxidation, strengthen the effect of immunocyte, in general food, have the vitamin E of more content with beans, wheat embryo, vegetables and fruits, vegetable oil, drupe class, still, because modern's eating habit changes, diet is unbalanced, and the content of vitamin E that therefore can absorb from food is very low.
So, must be improving immunity and adjusting Biology Barrier of Gastrointestinal Tract, balanced diet, adding the attention such as sharp movement is equal to, the comprehensive regulation to disease of digestive tract.In disease of digestive tract, except for cause of disease medication, supplement the nutrients, improve immunity, change flora in body, regulating and recovering digestion and absorption function is effective approach.Have at present much for gastral health products, but it emphasizes the nutrition such as an interior absorption and protein more, and ignored balanced nutritious as vitamin (especially rare vitamin is as vitamin, K), mineral matter digestion, the compound synergy of dietary fibre etc.
Summary of the invention
For overcoming the defect of prior art; the object of the present invention is to provide a kind of composition that can regulate human body flora and immunologic function; can be processed into tablet, oral liquid, pulvis of Foods or drinks etc.; to improve immunity, change human body flora, thereby reach prevention or treatment disease of digestive tract; protection stomach environment; prevention of obesity, reduces seat sore, promotes and keeps fit.
The technical solution adopted in the present invention is as follows for achieving the above object:
Can regulate a composition for human body flora and immunologic function, it comprises the following component in weight portion:
In preferred scheme, the composition that can regulate human body flora and immunologic function of the present invention comprises the following component in weight portion
In the present invention, described vegetables and fruits water extract and natural activity polysaccharide are respectively to extract concentrate by following steps
1) select raw material: fruits and vegetables are selected fresh feed;
2) raw material processing: the above-mentioned raw material of choosing is cleaned to impurity elimination, is cut into silk or block;
3) extract: raw material after treatment adds water, the 5-30 that water is raw material doubly, extract or ultrasonic wave extracts 2-3 time by Soxhlet, by each extracting liquid filtering, and merging filtrate, wherein each extraction time is 1-3 hour, temperature is controlled at room temperature-100 ° C;
4) concentrated: the 1/3-1/2 that the filtrate decompression after above-mentioned merging is concentrated into former filtrate volume;
5) dry: spraying is dried or heats the dry 5-40 of static state second, preserves stand-by.
Wherein vegetables and fruits class dry powder be fresh vegetables and fruits are cleaned, are dehydrated after with the directly powder of the 20-80 μ m of pulverizing of ball mill, wherein the rotating speed of ball mill barrel is 18-38r/min.Dry method can make natural drying or hyperthermia drying or freeze drying, and the method, for the conventional method that those skilled in the art can grasp, is not described in detail at this; In order to facilitate the follow-up different preparations such as tablet, capsule, spraying that are easily processed into.
In the present invention, preferred vegetables and fruits class plant is that greengrocery is or/and one or more in melon and fruit class; Wherein vegetables are that the root of cabbage, wild cabbage class, mustard, aquatic vegetables, radish kind is or/and one or more mixing in leaf, celery, asparagus, capsicum etc., wherein cabbage is selected from pakchoi, cabbage heart, Chinese cabbage, purple tsai-tai, spinach, rape, turnip, celery, one or more in purple flowering stalk; Wild cabbage class is selected from one or more in cabbage, cauliflower, cabbage mustard, broccoli, kohlrabi etc.; Mustard be in leaf mustard, stem mustard (dish), root mustard (root-mustard) etc. one or more, aquatic vegetables, radish kind.Wherein melon and fruit is one or more mixing in apple, pears, orange, watermelon, blueberry, tomato, eggplant, strawberry, pawpaw etc., the invention is not restricted to above several.
Can regulate a composition for human body flora and immunologic function, it comprises the following component in weight portion:
Coarse food grain extract described in the present invention is to extract concentrate by following steps:
1) select raw material: coarse food grain is selected the raw material of full grains;
2) raw material processing: the above-mentioned raw material of choosing is cleaned to impurity elimination, is cut into silk or block;
3) extract: raw material after treatment adds water, the 5-30 that water is raw material doubly, extract or ultrasonic wave extracts 2-3 time by Soxhlet, by each extracting liquid filtering, and merging filtrate, wherein each extraction time is 1-3 hour, temperature is controlled at 60-100 ° of C;
4) concentrated: the 1/3-1/2 that the filtrate decompression after above-mentioned merging is concentrated into former filtrate volume;
5) dry: spraying is dried 5-40 second, preserves stand-by.
Coarse food grain described in the present invention is one or more mixing in corn, millet, purple rice, Chinese sorghum, oat, buckwheat, wheat bran, soya bean, green soya bean, red bean, mung bean, Ipomoea batatas etc., but is not limited to above several; After coarse food grain drying, again with the directly powder of the 20-80 μ m of pulverizing of ball mill, wherein the rotating speed of ball mill barrel is 18-38r/min.Dry method can make natural drying or hyperthermia drying or freeze drying, and the method, for the conventional method that those skilled in the art can grasp, is not described in detail at this.
Can regulate a composition for human body flora and immunologic function, it comprises the following component in weight portion:
In such scheme, described fruit juice is that the fresh of one or both in apple, tangerine, pears, blueberry, strawberry, tomato squeezed the juice.
Natural activity polysaccharide of the present invention is to extract concentrate by following steps:
1) select raw material: the Radix Astragali is selected without worm without the mould raw material that meets Chinese pharmacopoeia standard;
2) raw material processing: the above-mentioned raw material of choosing is cleaned to impurity elimination, is cut into silk or block;
3) extract: raw material after treatment adds water, the 5-30 that water is raw material doubly, extract or ultrasonic wave extracts 2-3 time by Soxhlet, by each extracting liquid filtering, and merging filtrate, wherein each extraction time is 1-3 hour, temperature is controlled at 60-100 ° of C;
4) concentrated: the 1/3-1/2 that the filtrate decompression after above-mentioned merging is concentrated into former filtrate volume;
5) dry: spraying is dried 5-40 second, preserves, stand-by.
On the basis of such scheme, the composition that can regulate human body flora and immunologic function of the present invention also comprises the edible algae 0-50 part in weight portion, and described edible algae is one or more mixing in laver, asparagus, undaria pinnitafida, Ma Nizao, sea-tangle.
In the present invention, mentioned natural activity polysaccharide is the polysaccharose substance that can improve immunity; Preferably one or more mixing in astragalus polyose, date polysaccharide, Polysaccharides in Bamboo Leaves, Gynostemma pentaphylla polysaccharide, Cordyceps sinensis polysaccharide, the thick polysaccharide of black soya bean, fig polysaccharide, hericium erinaceum polysaccharide, Chinese gooseberry polysaccharide, soluble polysaccharide, Dihuang polysaccharide, LBP-X, spirulina polysaccharide, eucommia bark polycose, Fructus Ligustri Lucidi polysaccharide.Natural activity polysaccharide has activating cell, it is aging to suppress, strengthen immunologic function, prevent disease, the recovery from illness of promotion disease, regulate human physiological functions, antitumor, radioresistance, anti-oxidant, anti-anoxic, antiallergy, anti-inflammatory, reducing blood lipid, reduction blood viscosity, hypoglycemic effect.
And vitamin C have promote ossein biosynthesis, be beneficial to tissue injury mouth the metabolism of healing sooner, promote tyrosine and tryptophan in amino acid, extend the human body life-span, improve iron, calcium and folic acid utilization, improve fat and lipoid particularly cholesterol metabolism, prevention cardiovascular disease, promote tooth and bone growth, prevent that gum is hemorrhage, the enhancing human body anti-stress ability of environment and the function of immunity to external world.The present invention adopts the mutual coordinated of flavonoids water extract and propolis and vitamin C, make antibacterial and strengthen immune effect improve and improve, lead to again and in formula, add vegetables and fruits dry powder/water extract or coarse food grain dry powder/or water extract or fruit juice, in improving human body flora and immunity, be conducive to the balanced diet of human body.
Beneficial effect of the present invention is: composition of the present invention can regulate the unbalance of human body flora and strengthen immune function of human body; there is the stomach of conciliation, increase enterogastric peristalsis, ventilation and protect the effects such as stomach film, to relieving the effect of alcohol and protecting digestive system to have good effect.The product that contains composition of the present invention can anti-treating dental ulcer, to bleeding gums, and halitosis or hydrochloric acid in gastric juice, stomachache all has certain booster action.Prescription of the present invention is simple, and raw material sources are easy, in extensive range; Easy to make, can greatly promote the bioavilability of material, and can carry out harmony to material composition well and distribute combination, bring into play its optimal efficacy.Can effectively regulate human body flora and immunologic function, for human health is created good condition.
Below in conjunction with concrete embodiment, the present invention is described in further detail.
Detailed description of the invention
Scheme one: described a kind of composition that can regulate human body flora and immunologic function, it comprises the following component in weight portion:
Wherein embodiment 1-6 is according to the formula preparation of scheme one, and the concrete formulation selection of embodiment 1-6 is in table 1:
Table 1
Application Example 1
Get any composition 1.8g in embodiment 1-3 or embodiment 5-6, add 0.2g microcrystalline cellulose, mix, be pressed into tablet, can suitably add sugar and flavouring agent in order to improve taste.Investigate and suffer from case 30 examples of canker sore because of hypoimmunity, the male sex 10 people, women 20 people, there is this product of taking for second day of canker sore in patient, and every day three times, 28 examples that heal in 3 days, reach 90%, wherein all healed after five days.
Application Example 2
Get the composition 10g in embodiment 4, add 5g white sugar, mix, make beverage.Drink once every day.Investigate constipation patient case 20 examples, the male sex 10 people, women 10 people, patient is occurring to take this product after constipation, and every day three times, 17 examples that heal in 3 days, reach 85%, wherein all healed after five days.
Scheme two: a kind of composition that can regulate human body flora and immunologic function, it comprises the following component in weight portion:
Wherein embodiment 7-12 is according to the formula preparation of scheme two, and the concrete formulation selection of embodiment 7-12 is in table 2:
Table 2
Application Example 3
Get any composition 10g in embodiment 7-9 or embodiment 11-12, add white sugar and water, be modulated into pasty state.Investigate easy catching a cold physique patient 30 examples, the male sex 10 people, women 20 people, these crowds are easy to catch cold, and the frequency of flu is about 1 month once, adhere to taking product of the present invention, the number that occurs flu in twice, 3 of every day is 14 people, has the flu that do not occur in these 3 months over half.
Application Example 2
Get the composition 10g in embodiment 10, add 5g white sugar, mix, make beverage.Investigation suffers from patient's 30 examples of hydrochloric acid in gastric juice, the male sex 10 people, and women 20 people, adhere to taking product of the present invention, and the number that fully recover twice, 7 day every day is afterwards 18 people.
Scheme three: a kind of composition that can regulate human body flora and immunologic function, it comprises the following component in weight portion:
Wherein embodiment 13-18 is according to the formula preparation of scheme two, and the concrete formulation selection of embodiment 13-18 is in table 2:
Table 2
Application Example 5
Get respectively embodiment 13-18 composition 20ml add syrup to be mixed with the beverage of 50ml, and add the Tea Polyphenols that accounts for beverage quality 1 ‰.Investigate easy catching a cold physique patient 30 examples, the male sex 10 people, women 20 people, these crowds are easy to catch cold, and the frequency of flu is about 1 month at every turn, adheres to taking product of the present invention, every day three times, occurs that the number of flu is 12 people in 3, has 60% people in these 3 months, not occur flu.
Claims (3)
1. the composition that can regulate human body flora and immunologic function, is characterized in that: the component by following weight portion meter forms:
Described natural activity polysaccharide is one or more mixing in astragalus polyose, date polysaccharide, Polysaccharides in Bamboo Leaves, Gynostemma pentaphylla polysaccharide, Cordyceps sinensis polysaccharide, the thick polysaccharide of black soya bean, fig polysaccharide, hericium erinaceum polysaccharide, Chinese gooseberry polysaccharide, soluble polysaccharide, Dihuang polysaccharide, LBP-X, spirulina polysaccharide, eucommia bark polycose, Fructus Ligustri Lucidi polysaccharide;
Described vegetables and fruits are that vegetables are or/and melon and fruit; Wherein vegetables be the root of cabbage, wild cabbage class, mustard, aquatic vegetables, radish kind or/and one or more in leaf, celery, asparagus, capsicum mix, melon and fruit is one or more mixing in apple, pears, orange, watermelon, blueberry, strawberry, pawpaw;
Described edible algae is one or more mixing in laver, asparagus, undaria pinnitafida, Ma Nizao, sea-tangle;
Described vegetables and fruits water extract is that after extracting concentrate by following steps, spraying is dried acquisition:
1) select raw material: vegetables and fruits are selected fresh feed;
2) raw material processing: the above-mentioned raw material of choosing is cleaned to impurity elimination, is cut into silk or block;
3) extract: raw material after treatment adds water, doubly, ultrasonic wave extracts 2-3 time the 5-30 that water is raw material, by each extracting liquid filtering, and merging filtrate, wherein each extraction time is 1-3 hour, temperature is controlled at 60-100 DEG C;
4) concentrated: the 1/3-1/2 that the filtrate decompression after above-mentioned merging is concentrated into former filtrate volume;
5) dry: spraying is dried 5-40 second, preserves stand-by.
2. the composition that can regulate human body flora and immunologic function according to claim 1, is characterized in that: the component by following weight portion meter forms:
3. the composition that can regulate human body flora and immunologic function according to claim 1, is characterized in that: when ultrasonic wave extracts, hyperacoustic frequency is 20-100kHz.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210278247.0A CN102813113B (en) | 2012-08-06 | 2012-08-06 | Composition capable of regulating human flora and immune function |
| PCT/CN2013/072131 WO2014023096A1 (en) | 2012-08-06 | 2013-03-04 | Composition capable of regulating human flora and immune function |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210278247.0A CN102813113B (en) | 2012-08-06 | 2012-08-06 | Composition capable of regulating human flora and immune function |
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| CN102813113A CN102813113A (en) | 2012-12-12 |
| CN102813113B true CN102813113B (en) | 2014-06-25 |
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| CN102813113B (en) * | 2012-08-06 | 2014-06-25 | 广州博能生物科技有限公司 | Composition capable of regulating human flora and immune function |
| CN103125802B (en) * | 2013-03-11 | 2014-07-30 | 宁夏原野蜂业有限公司 | Nutrition taking propolis cream, medlar cream, honey and desert ginseng powder as raw materials and preparation method of nutrition |
| CN103190626B (en) * | 2013-04-17 | 2014-12-03 | 肖天存 | Fruit and vegetable food for treating oral ulcer and preparation method of fruit and vegetable food |
| CN103461612A (en) * | 2013-10-09 | 2013-12-25 | 北京绿源求证科技发展有限责任公司 | Food stomach-nourishing tea electuary protecting stomach lining |
| CN104543811B (en) * | 2013-10-21 | 2018-05-15 | 广州博能生物科技有限公司 | Improve natural composite powder of immunity and its preparation method and application |
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| CN102813113A (en) | 2012-12-12 |
| WO2014023096A1 (en) | 2014-02-13 |
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