CN105998691A - Traditional Chinese medicine preparation for treating calcaneodynia and preparation method of traditional Chinese medicine preparation - Google Patents

Abstract

The invention provides a traditional Chinese medicine preparation for treating calcaneodynia and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the following medicine raw materials: rhizomes of smilax mairei, leaves of delavay neocinnamomum, herbs of fanshaped corallodiscus, roots of hairless rockvine, herba lycopodii, roots of double teeth pubescent angelica, roots of ficus beecheyana, evening primrose, boehmeria macrophylla hornem, pterocyclus rivulorum, bark of largeleaf dogwood, fewflower lysionotus, herbs of denseflower bulbophyllum, adenia chevaliert gagnep, goral fat, farges decaisnea roots, fruits of purpleflower holly, herbs of laminated sanicle and entire micromelum. The traditional Chinese medicine preparation for treating the calcaneodynia has the beneficial effects as follows: the calcaneodynia is treated in cooperation with a conventional western medicine method, the preparation is safe and convenient to use, the treatment effect is better, toxic and side effects and adverse reactions are avoided, and the preparation process is simple.

Description

A kind of Chinese medicine preparation treating calcaneodynia and preparation method thereof

Technical field

The present invention relates to engineering of traditional Chinese medicine technical field, particularly relate to a kind of Chinese medicine preparation treating calcaneodynia And preparation method thereof.

Background technology

Calcaneodynia is the general name of painful diseases around heel, is apt to occur in middle age or the old age in 40-60 year People.Great inconvenience is brought to middle-aged and elderly people live and work.According to medical statistics, more than 50 years old old people Suffering from talalgia disease and account for 25%, particularly overweight people is more easy to primary disease.In recent years, due to high-heel shoes Popular, the long-term damage being also easily caused heel through high heel.About the cause of disease of calcaneodynia, many with Strain and degeneration have substantial connection, pain caused by chronic strain, its onset around polyphyly calcaneal tuberosity Hidden attacking, the course of disease is longer.Due to walking, the aggravating activities of standing for a long time, cause the fat pad of heel portion, synovial bursa, Aponeurosis (aponeuroses), ligament by stretch injury, contrafluxion edema, produce aseptic inflammation, with the passing of time produce cicatrix, Regression atrophy, effect with lower fat pad decline so that it is damping, buffering ability reduces, long-term walking, Under for a long time inducement effect such as station, the existence of bony spur in addition, easily cause calcaneus periosteum, synovial bursa, aponeurosis (aponeuroses) Damage thus cause contrafluxion, edema, hypertrophy and generation aseptic inflammation, then produce pain symptom. The clinical common cause of disease is with end bursitis and calcanean spur, has data to show, calcaneodynia patient only has about 37% Patient have bony spur, say, that the Etiological of calcaneodynia is with end bursitis.It is generally divided into three clinically Big class: with rear pain, including rear bursitis, heel string stop lacerated wound, rheumatoid calcaneitis；With lower pain, Mainly have between the sole of the foot that film is scorching, bursitis, calcaneus fat pad inflammation under calcaneus；Calcaneus is sick, as calcaneal osteomyelitis, Bone tuberculosis, bone tumor.

Motherland's medical science thinks that the many Liver and kidney with age of calcaneus pain are deficient, and muscles and bones is lost and supported, again sense wind-cold damp pathogen institute Cause, because ferritic is weak, or because of wound, walking for a long time.Damage muscles and bones causes stagnation of QI-blood, phlegm resistance, for a long time Within give up in bone, invade and formed in bone, be i.e. Miraculous Pivot meaning " evil in kidney then sick osteopathia ".Heel is The stress heavy burden position that human body is main.Owing to overworking, waist feet wound is damaged, weak bone flaccidity of tendon and muscle, the highest year People, deficiency of spleen-YANG and kidneyYANG, kidney essense loss is not enough to moisten nourishing muscle and tendon bone, therefore sends out heel pain.If daily life is caused careless, Dew is sleeping greedy cool or occupies wetland for a long time, then the heresy that wind and cold is wet is taken advantage of a weak point in opponent's defence and people, and numbness resistance meridians, blood vessels are unsmooth, then send out Disease for numbness." generation of Plain Questions the five internal organs " piece is said: " the tissue connected with the kidney being bone "." Plain Questions YIN YANG classification of natural phenomena is big Opinion " say: " kidney producing bone marrow ", " being bone at body ".All cloud the kidney generating marrow and dominating bones, because kidney storing essence, the raw marrow of essence, Marrow nourishing bone, so the growth of bone, growing, repairing, must rely on nourishing and the promotion of kidney vital essence." all Source of disease waits opinion " say: " people of husband's impairment caused by overstrain, kidney qi is deficient, and kidney main waist foot ".Imply that due to kidney vital essence Loss can cause waist foot pain pain.

Summary of the invention

The technical problem to be solved is, utilizes the theory of Chinese medical science that China is traditional, it is provided that a kind of Determined curative effect and the Chinese medicine preparation for the treatment of calcaneodynia free of toxic effects and preparation method thereof.

In order to solve above-mentioned technical problem, the invention provides a kind of Chinese medicine preparation treating calcaneodynia, institute State Chinese medicine preparation and include following raw medicinal material: Rhizoma Smilacis, Folium Neocinnamomi Delavayi, Herba Corallodisci Flabellati, Radix Tetrastigmatis Glabri, steal muscle On Radix Angelicae Pubescentis careless, careless, Radix Fici beecheyanae, Radix Oenotherae erythrosepalae, Herba Boehmeriae platyphllae, Yunnan Rhizoma Et Radix Notopterygii, Cortex Corni macrophyllae, Herba Lysionoti Pauciflori, fruit Leaf, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep., Adeps Naemorhedi, Radix decaisneae fargesii, Fructus Ilicis Purpureae, Herba Saniculae lamelligerae and Radix Micromeli Integerrimi.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can be preferably: Rhizoma Smilacis 15～ 25 parts, Folium Neocinnamomi Delavayi 30～40 parts, Herba Corallodisci Flabellati 5～15 parts, Radix Tetrastigmatis Glabri 15～30 parts, Primula szechuanica 10～ 20 parts, grass Radix Angelicae Pubescentis 25～35 parts, Radix Fici beecheyanae 5～15 parts, Radix Oenotherae erythrosepalae 30～40 parts, Herba Boehmeriae platyphllae 15～ 25 parts, Yunnan Rhizoma Et Radix Notopterygii 20～30 parts, Cortex Corni macrophyllae 10～20 parts, Herba Lysionoti Pauciflori 15～30 parts, Herba Bulbophylli Odoratissim 5～ 15 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 10～20 parts, Adeps Naemorhedi 25～35 parts, Radix decaisneae fargesii 15～30 parts, Fructus Ilicis Purpureae 5～15 Part, Herba Saniculae lamelligerae 20～30 parts and Radix Micromeli Integerrimi 15～25 parts.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can also be more preferably: red Bi 15～20 parts, Folium Neocinnamomi Delavayi 30～35 parts, Herba Corallodisci Flabellati 10～15 parts, Radix Tetrastigmatis Glabri 20～25 parts, Primula szechuanica 10～15 parts, grass Radix Angelicae Pubescentis 30～35 parts, Radix Fici beecheyanae 10～15 parts, Radix Oenotherae erythrosepalae 30～35 Part, Herba Boehmeriae platyphllae 15～20 parts, Yunnan Rhizoma Et Radix Notopterygii 25～30 parts, Cortex Corni macrophyllae 15～20 parts, Herba Lysionoti Pauciflori 20～ 25 parts, Herba Bulbophylli Odoratissim 5～10 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 10～15 parts, Adeps Naemorhedi 25～30 parts, Radix decaisneae fargesii 20～25 Part, Fructus Ilicis Purpureae 5～10 parts, Herba Saniculae lamelligerae 20～25 parts and Radix Micromeli Integerrimi 15～20 parts.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can also be more preferably: red Bi 16 parts, Folium Neocinnamomi Delavayi 35 parts, Herba Corallodisci Flabellati 12 parts, Radix Tetrastigmatis Glabri 21 parts, Primula szechuanica 15 parts, grass Radix Angelicae Pubescentis 31 parts, Radix Fici beecheyanae 15 parts, Radix Oenotherae erythrosepalae 32 parts, Herba Boehmeriae platyphllae 19 parts, Yunnan Rhizoma Et Radix Notopterygii 26 parts, fourth Coated split leather 20 parts, Herba Lysionoti Pauciflori 21 parts, Herba Bulbophylli Odoratissim 10 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 15 parts, Adeps Naemorhedi 26 parts, Radix decaisneae fargesii 25 parts, Fructus Ilicis Purpureae 7 parts, Herba Saniculae lamelligerae 25 parts and Radix Micromeli Integerrimi 16 parts.

When the dosage form of described Chinese medicine preparation is granule, its preparation method comprises the following steps:

Step one: mixed in described ratio by described raw medicinal material, adds relative to mixture 5～the alcohol of 6 times Concentration is the ethanol of 80%～95%, is heated to boiling reflux 4～6 hours, filters, is molten with backflow Agent, with filtering residue as solute, uses percolation with the speed slowly percolation of per minute 1～2ml, collects percolation Liquid, when being evaporated to 50～60 DEG C subsequently under vacuum 0.06～0.08Mpa, relative density is The mastic of 1.05～1.10, is spray-dried, and the inlet temperature 160 of spray dryer～175 DEG C, goes out pathogenic wind-warm Spend 80～85 DEG C, be ground into powder subsequently, make dried cream powder；

Step 2: add relative to dried cream powder quality 0.2～the cane sugar powder of 0.4 times in the dried cream powder obtained With the dextrin of 0.1～0.2 times, make granule, be dried in 40～50 DEG C, it is thus achieved that granule.

When the dosage form of described Chinese medicine preparation is tablet, its preparation method comprises the following steps:

The first step, by Rhizoma Smilacis, Folium Neocinnamomi Delavayi, Herba Corallodisci Flabellati, Radix Tetrastigmatis Glabri, Primula szechuanica, grass Radix Angelicae Pubescentis, cattle Milk slurry root, Radix Oenotherae erythrosepalae, Herba Boehmeriae platyphllae, Yunnan Rhizoma Et Radix Notopterygii and Cortex Corni macrophyllae are mixed in proportion, and add relative to mixture 3 Times～alcohol reflux that 5 times amount determining alcohols are 55%～65% 2 times～4 times, each 2 hours～3 Hour, to filter, filtrate merges, and reclaims ethanol, and being concentrated into 70 DEG C of relative densities is 1.30～1.32 Mastic, standby；

Second step, is mixed in proportion surplus stock medical material, adds relative to mixture 3～5 times amount water, boils Boil 2～4 hours, filter, be concentrated into the mastic that 70 DEG C of relative densities are 1.27～1.29；

3rd step, the mastic mixing that the first step, second step are obtained, 55 DEG C～65 DEG C of reduced vacuum are dried, Get dry extract powder；

4th step, carries out mixing process by described dried cream powder and starch, obtains mastic mixture；Described Mastic and the weight ratio of starch be 1: 0.01～0.02；Described mastic mixture is carried out pelletization treatment, Dried, the mastic compound particles obtained；

5th step, is carried out at mixing successively by described mastic compound particles and Pulvis Talci, magnesium stearate Reason, tabletting process, Cotton seeds, obtain Chinese medicine preparation tablet finished product；Described granule, Pulvis Talci, The weight ratio of magnesium stearate is 100: 1～3: 0.15～0.3.

Beneficial effects of the present invention: the Chinese medicine preparation that calcaneodynia of the present invention uses, coordinates regular western medicine Treatment calcaneodynia, safe and convenient to use, therapeutic effect is more preferable, has no side effect and untoward reaction, preparation Technique is simple.

Detailed description of the invention

The invention provides a kind of Chinese medicine preparation treating calcaneodynia, Chinese medicine preparation includes following crude drug Material: Rhizoma Smilacis, Folium Neocinnamomi Delavayi, Herba Corallodisci Flabellati, Radix Tetrastigmatis Glabri, Primula szechuanica, grass Radix Angelicae Pubescentis, Radix Fici beecheyanae, the moon See grass, Herba Boehmeriae platyphllae, Yunnan Rhizoma Et Radix Notopterygii, Cortex Corni macrophyllae, Herba Lysionoti Pauciflori, Herba Bulbophylli Odoratissim, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep., Adeps Naemorhedi, Radix decaisneae fargesii, Fructus Ilicis Purpureae, Herba Saniculae lamelligerae and Radix Micromeli Integerrimi.

The pharmacology of various raw medicinal materials is as follows:

Rhizoma Smilacis: [another name] Yunnan red tea Bi, Rhizoma Smilacis Glabrae, little Bi, Hua Huateng, flower Bi.[come Source] medical material Ji Yuan: for the rhizome of the stingless Rhizoma Smilacis Chinensis of liliaceous plant.[nature and flavor] are bitter；Sweet；Flat.[merit Can cure mainly] expelling wind and removing dampness；Relieving stranguria by diuresis；Solve sore.Main air pain of dampness syndrome；Edema；Stranguria with turbid discharge；Skin ulcer Furuncle and phyma poison.[each discussion] 1. " Traditional Chinese Medicine in Sichuan will ": wind-damp dispelling, distinguish turbid, profit joint, solve skin ulcer Poison.Dispelling the wind and dampness pathogens pain, waist knee joint arthralgia pain, stranguria with turbid discharge and syphilis malignant boil.2. " choosing of Yunnan Chinese herbal medicine ": dispel Wind dehumidifies, treating stranguria, diuretic, antiinflammatory, removing toxic substances.Treating rheumatic arthritis, urinary system infection, chronic stomach Inflammation, menoxenia, furuncle.[extracts] " China's book on Chinese herbal medicine "

Folium Neocinnamomi Delavayi: [another name] Herba Pelargonii Graveolentis, Lignum nanmu is fragrant, Folium Mume is fragrant, Cornu Caprae seu Ovis is fragrant, Cortex Linderae Fragrantis.[source] Medical material Ji Yuan: for the leaf of the new Camphor tree of canella.[nature and flavor] are pungent；Puckery；Temperature.[return through] liver；Spleen channel. [function cures mainly] wind-damp dispelling；Relaxing muscles and tendons network；Dispersing cold for relieving pain；External is stopped blooding.Main air wet sense emits；Rheumatism numbness Bitterly；Cold syndrome of the stomach pain；Traumatic pain, knife injury is hemorrhage.[extracts] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "

Herba Corallodisci Flabellati: [another name] rock fingernail, relieving palpitation grass, stone lotus, Herba Hylotelephii Mingjiniani, Graptopelaum Paraguayense.[source] Medical material Ji Yuan: plant the herb of Herba Corallodisci Flabellati for Gesneriaceae.[nature and flavor] bitter in the mouth；Pungent；Cold in nature.[return through] Liver Channel.[function cures mainly] clearing away damp-heat；Solve sore；Promoting blood circulation and stopping pain.Main damp and hot arthralgia pain；Sore swollen toxin； Laryngopharynx swelling and pain；Leucorrhea with red and white discharge；Traumatic injury；Traumatic hemorrhage.[each discussion] 1. " Yunnan Chinese herbal medicine ": Promoting blood circulation and detoxication, reducing swelling and alleviating pain.Control menoxenia, leucorrhea with red and white discharge, cardiopalmus, traumatic injury, knife injury, carbuncle sore, Stubborn dermatitis.2. " Kunming conventional medical herbs among the people ": heat-clearing and toxic substances removing, dehumidifying.Control damp and hot arthromyodynia, parotitis, Laryngopharynx swelling and pain.[extracts] " China's book on Chinese herbal medicine "

Radix Tetrastigmatis Glabri: [another name] Radix seu Herba Tetrastigmatis Hypoglauci, Herba Parthenocissi Himalayanae, little red robe, Rhizoma Rohdeae Japonicae, slungshot lotus.[come Source] medical material Ji Yuan: climb root or the Herb of rattan without hair precipice for vitaceae.[nature and flavor] are pungent；Temperature.[return Warp] spleen；Kidney channel.[function cures mainly] expelling wind and removing dampness；Invigorating blood circulation can network.Main air pain of dampness syndrome；Traumatic injury； Traumatic hemorrhage.[each discussion] 1. " Yunnan Chinese herbal medicine ": synthetism granulation promoting, hemostasis and anti-inflammation.Control fracture, Scrofula, traumatic hemorrhage.2. " Kunming conventional medical herbs among the people ": relaxing muscles and tendons and activating QI and blood in the collateral, hemostasia and promoting granulation.Control traumatic injury Damage, rheumatic Bi syndrome, joint bones and muscles pain.[extracts] " China's book on Chinese herbal medicine "

Primula szechuanica: [source] medical material Ji Yuan: for the herb of Ofthe Primulaceae Herba Primulae szechuanicae.[nature and flavor] Pungent；Slightly warm in nature.[function cures mainly] promoting blood circulation and detumescence.Main treating swelling and pain by traumatic injury.[extracts] " China's book on Chinese herbal medicine "

Grass Radix Angelicae Pubescentis: [another name] NIUJIAOQI, JIUGUNIU, Radix Ariliae, pearl money grass, Colophonium infantile malnutrition medicine.[come Source] medical material Ji Yuan: for the root of Araliaceae Yunnan Radix Ariliae.[nature and flavor] bitter in the mouth；Pungent；Property is micro- Temperature.[function cures mainly] dispersing wind-cold；Invigorating spleen for diuresis；Relaxing muscles and tendons to promote blood circulation；Preventing the attack (or recurrence) of malaria.Main anemofrigid cold；Cough Cough；Edema due to deficiency of the spleen；Infantile malnutrition；Pain in chest and hypochondrium；Treating swelling and pain by traumatic injury；Rheumatalgia；Lumbago；Fracture； Menoxenia；Traumatic hemorrhage；Malaria.[extracts] " China's book on Chinese herbal medicine "

Radix Fici beecheyanae: [another name] hair Fructus Fici Beecheyanae root.[source] medical material Ji Yuan: for moraceae plants beauty The root of fruit.[nature and flavor] are sweet；Pungent；Warm in nature.[return through] lung；Spleen；Kidney channel.[function cures mainly] benefit Gas spleen invigorating；Promoting blood circulation to remove obstruction in the collateral；Expelling wind and removing dampness.Main overstrain is weak；Lack of appetite；Agalactia；Insufficiency of the spleen leucorrhea； Proctoptosis；Menoxenia；Wind syndrome of head pain；Traumatic injury；Rheumatic arthralgia.[each discussion] 1. " good fortune Build traditional herbal medicine ": promoting flow of QI and blood, removing toxic substances of dispeling the wind.Dispelling the wind and dampness pathogens arthralgia, traumatic injury.2. " Fujian East book on Chinese herbal medicine ": invigorating the spleen and replenishing QI, invigorating the spleen for eliminating dampness, bone and muscle strengthening, detumescence, promoting blood circulation and detoxication.Control the middle deficiency of vital energy weak, QI and blood is on the decline, and extremity are aching and limp, stiffness of the muscle and joint, amenorrhea, galactostasis.3. " Zhejiang conventional medical herbs among the people ": Mend waist kidney, bone and muscle strengthening, expelling wind and removing dampness.[extracts] " China's book on Chinese herbal medicine "

Radix Oenotherae erythrosepalae: [another name] Radix Helicteris, Radix Oenotherae erythrosepalae.[source] medical material Ji Yuan: plant for Oenotheraceae The root of thing Radix Oenotherae erythrosepalae.[nature and flavor] sweet in the mouth；Bitter；Warm in nature.[function cures mainly] wind-damp dispelling；Bone and muscle strengthening. Main anemofrigid-damp arthralgia；Soreness of bones and muscles.[extracts] " China's book on Chinese herbal medicine "

Herba Boehmeriae platyphllae: [another name] Debregeasia orientalis C. J. Chen, Sambucus chinensis, DAJIEGU, big glutinous leaf.[source] medical material Ji Yuan: Herb or root for contrayerva Herba Boehmeriae platyphllae.[nature and flavor] mildly bitter flavor；Pungent；Warm in nature.[function cures mainly] Expelling wind and removing dampness；Removing obstruction in the collateral to relieve pain.Main air pain of dampness syndrome；Traumatic injury.[each discussion] " Xinhua's book on Chinese herbal medicine guiding principle Want ": herb: treating rheumatic arthritis.[extracts] " China's book on Chinese herbal medicine "

Yunnan Rhizoma Et Radix Notopterygii: [another name] tap Rhizoma Et Radix Notopterygii, snakehead Rhizoma Et Radix Notopterygii.[source] medical material Ji Yuan: for Umbelliferae The root of plant lobus cardiacus rib celery.[nature and flavor] acrid in the mouth；Bitter；Warm in nature.[function cures mainly] expelling wind and removing dampness； Removing obstruction in the collateral to relieve pain.Main anemofrigid cold；Anemofrigid-damp arthralgia；Muscle arteries and veins contracture；Headache；Abdominal pain.[extracts] " in China's book on Chinese herbal medicine "

Cortex Corni macrophyllae: [another name] pine poplar skin.[source] medical material Ji Yuan: for Cornaceae plant wood Bark.[nature and flavor] bitter in the mouth；Property flat.[function cures mainly] dispelling wind and removing obstruction in the collateral；Dampness removing antidiarrheal.Main muscles and bones Pain；Quadriplegia；Dysentery；Watery diarrhea is suffered from abdominal pain.[each discussion] " Shaanxi Chinese herbal medicine ": only dispel the wind Bitterly, dredge the meridian passage.Control bones and muscles pain, lumbago and skelalgia, quadriplegia.[extracts] " China's book on Chinese herbal medicine "

Herba Lysionoti Pauciflori: [another name] black crow bone, Lysionotus pauciflorus Maxim., Herba Ophiorrhizae japonicae, rock orchid, Parmelia saxatilis Ach., Shi Hu, rock Ginseng.[source] medical material Ji Yuan: for the herb of Gesneriaceae Herba Lysionoti Pauciflori.[nature and flavor] bitter in the mouth；Pungent； Property flat.[function cures mainly] expelling wind and removing dampness；Preventing phlegm from forming and stopping coughing；Blood stasis dispelling stimulates the menstrual flow.Main air pain of dampness syndrome；Cough with asthma expectorant Many；Menoxenia；Dysmenorrhea；Traumatic injury.[each discussion] 1. " classifies herbal ": control haematemesis, Waist and knee, goes wind to dehumidify, traumatic injury.2. " Traditional Chinese Medicine in Sichuan will ": control women's metrorrhagia and leukorrhagia, rheumatic arthralgia, Infant malnutrition and internal injury are breathed with cough.3. " mountain of papers Chinese herbal medicine ": heat clearing and damp drying, reducing swelling and alleviating pain.Control bacillary dysentery, Rheumatalgia, cutization pyogenic infection.[extracts] " China's book on Chinese herbal medicine "

Herba Bulbophylli Odoratissim: [another name] little Herba Bulbophylli Odoratissim, Bulbophyllum calodictyon schlecht., extremely fragrant Bulbophyllum, elaeagnus conferta fruits.[source] Medical material Ji Yuan: for the herb of orchid Bulbophyllum odoratissimum Lindl..[nature and flavor] are sweet；Light；Cool.[return through] Lung；Liver；Kidney channel.[function cures mainly] moistening the lung and resolving phlegm；Removing obstruction in the collateral to relieve pain.Main hemoptysis of pulmonary tuberculosis；Chronic gas Guan Yan；Chronic pharyngitis；Hernia pain；Menoxenia；Rheumatic arthralgia；Traumatic injury.[each discussion] 1. " Kunming conventional medical herbs among the people ": wind-damp dispelling, active, circulation of qi promoting, pain relieving.2. " choosing of Yunnan Chinese herbal medicine ": Synthetism antiinflammatory, moistening the lung and resolving phlegm.Control fracture, pulmonary tuberculosis, spit blood, chronic tracheitis, pneumonia convalescent period, Chronic pharyngitis, menoxenia.3. " catalogue planted by Guizhou medicine ": clearing heat and moistening dryness, promoting the production of body fluid to quench thirst.[extracts] " China's book on Chinese herbal medicine "

Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep.: [another name] cartilage Sinomenium acutum, Yunlong party, cartilage wind, Caulis Entadae, Cipangopaludina chinensis are covered.[source] Medical material Ji Yuan: for the root of Passifloraceae plant Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep..[nature and flavor] sweet in the mouth；Micro-hardship；Cool in nature.[function Cure mainly] dispelling wind and removing obstruction in the collateral；Tonifying and lifting QI.Main gastric abscess；Rheumatic arthralgia；Uterine prolapse.[extracts] " in China's book on Chinese herbal medicine "

Adeps Naemorhedi: [source] medical material Ji Yuan: for bovid QINGYANG, ibex and argali fat Oil.[nature and flavor] are sweet；Temperature.[return through] heart channel.[function cures mainly] dispelling cold by warming the meridian；Regulating blood flow to alleviate pains. Main hernia disease.[extracts] " China's book on Chinese herbal medicine "

Radix decaisneae fargesii: [another name] cat melon, adhesion, cat dung bag, ghost finger, little bitter sugar, cat dung cylinder. [source] medical material Ji Yuan: for root or the stem of plants of Lardizabalaceae Radix decaisneae fargesii.[nature and flavor] Gan Xin；Pungent；Property Flat.[return through] returns lung；Liver Channel.[function cures mainly] expelling wind and removing dampness；Clearing away lung-heat to relieve cough.Main air pain of dampness syndrome； Anus is wet rotten；Pudendal pruritus；Pulmonary tuberculosis cough.[each discussion] 1. " Guizhou medical herbs ": clearing away lung-heat to relieve cough, drive Wind dehumidifies.[extracts] " China's book on Chinese herbal medicine "

Fructus Ilicis Purpureae: [another name] Ilicis Purpureae is real, freeze blue or green tree.[source] medical material Ji Yuan: plant for Aquifoliaceae The fruit of thing Ilicis Purpureae.[nature and flavor] are sweet；Bitter；Cool.[return through] liver；Kidney channel.[function cures mainly] mends Liver and kidney；Curing rheumatism；Arresting bleeding and healing up ulcer.Main early whitening of beard and hair；Wind shows arthralgia pain；Digestive ulcerative bleeding；Hemorrhoid； Ulcer being unable to heal.[each discussion] 1. " book on Chinese herbal medicine is looked for the truth ": the strong muscle of tonifying liver, reinforcing the kidney to strengthen the bone.2. " Jiangsu medicine Material will ": dispelling the wind and dampness pathogens arthralgia pain.[extracts] " China's book on Chinese herbal medicine "

Herba Saniculae lamelligerae: [another name] thin slice sanicle, Herba Saniculae lamelligerae, Herba boeae clarkeanae, goose palm foot grass, smallage. [source] medical material Ji Yuan: for samphire thin slice sanicle and the herb of sky blue sanicle.[nature and flavor] Acrid in the mouth；Sweet；Slightly warm in nature.[return through] returns lung；Liver Channel.[function cures mainly] is dispeled the wind and is delivered；Only reduce phlegm Cough；Promoting blood flow to regulate menstruation.Main flu；Cough；Asthma；Menoxenia；Amenorrhea；Dysmenorrhea；Skin ulcer swells；Traumatic injury Swell and ache；Traumatic hemorrhage.[each discussion] " Traditional Chinese Medicine in Sichuan will ": clearing heat and moistening lung, promoting the circulation of blood is stimulated the menstrual flow.Control Cough or void are coughed, women's amenorrhea lumbago.[extracts] " China's book on Chinese herbal medicine "

Radix Micromeli Integerrimi: [another name] chicken droppings tea wooden, wild is peppery, Flos Osmanthi Fragrantis, Pe1lionia tsoongii (Merr.) Merr..[source] medical material base Source: for root, bark or the leaf of rutaceae Radix Micromeli Integerrimi.[nature and flavor] bitter in the mouth, pungent；Warm in nature.[return Warp] stomach；Bladder；Lung meridian.[function cures mainly] dispelling wind to relieve the exterior syndrome；Warming middle-JIAO to promote flow of QI；Dissipating blood stasis for subsidence of swelling.Main flow Sense；Cold cough；Stomachache；Rheumatic arthralgia；Treating swelling and pain by traumatic injury；Fracture.[each discussion] 1. " Guangxi Chinese herbal medicine ": circulation of qi promoting is eliminated the phlegm, expelling wind and removing dampness, eliminating stasis to stop pain.Cure cold cough, stomachache, rheumatic ostalgia. 2. " choosing of Simao, Yunnan Chinese herbal medicine ": dispelling wind to relieve the exterior syndrome, warming middle-JIAO to promote flow of QI, dissipating blood stasis of subsiding a swelling, hemostasis.Control influenza, Malaria, traumatic injury, stomachache, rheumatic arthritis, traumatic hemorrhage, fracture.[extracts] " China Book on Chinese herbal medicine "

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can be preferably: Rhizoma Smilacis 15～ 25 parts, Folium Neocinnamomi Delavayi 30～40 parts, Herba Corallodisci Flabellati 5～15 parts, Radix Tetrastigmatis Glabri 15～30 parts, Primula szechuanica 10～ 20 parts, grass Radix Angelicae Pubescentis 25～35 parts, Radix Fici beecheyanae 5～15 parts, Radix Oenotherae erythrosepalae 30～40 parts, Herba Boehmeriae platyphllae 15～ 25 parts, Yunnan Rhizoma Et Radix Notopterygii 20～30 parts, Cortex Corni macrophyllae 10～20 parts, Herba Lysionoti Pauciflori 15～30 parts, Herba Bulbophylli Odoratissim 5～ 15 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 10～20 parts, Adeps Naemorhedi 25～35 parts, Radix decaisneae fargesii 15～30 parts, Fructus Ilicis Purpureae 5～15 Part, Herba Saniculae lamelligerae 20～30 parts and Radix Micromeli Integerrimi 15～25 parts.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can also be more preferably: red Bi 15～20 parts, Folium Neocinnamomi Delavayi 30～35 parts, Herba Corallodisci Flabellati 10～15 parts, Radix Tetrastigmatis Glabri 20～25 parts, Primula szechuanica 10～15 parts, grass Radix Angelicae Pubescentis 30～35 parts, Radix Fici beecheyanae 10～15 parts, Radix Oenotherae erythrosepalae 30～35 Part, Herba Boehmeriae platyphllae 15～20 parts, Yunnan Rhizoma Et Radix Notopterygii 25～30 parts, Cortex Corni macrophyllae 15～20 parts, Herba Lysionoti Pauciflori 20～ 25 parts, Herba Bulbophylli Odoratissim 5～10 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 10～15 parts, Adeps Naemorhedi 25～30 parts, Radix decaisneae fargesii 20～25 Part, Fructus Ilicis Purpureae 5～10 parts, Herba Saniculae lamelligerae 20～25 parts and Radix Micromeli Integerrimi 15～20 parts.

The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can also be more preferably: red Bi 16 parts, Folium Neocinnamomi Delavayi 35 parts, Herba Corallodisci Flabellati 12 parts, Radix Tetrastigmatis Glabri 21 parts, Primula szechuanica 15 parts, grass Radix Angelicae Pubescentis 31 parts, Radix Fici beecheyanae 15 parts, Radix Oenotherae erythrosepalae 32 parts, Herba Boehmeriae platyphllae 19 parts, Yunnan Rhizoma Et Radix Notopterygii 26 parts, fourth Coated split leather 20 parts, Herba Lysionoti Pauciflori 21 parts, Herba Bulbophylli Odoratissim 10 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 15 parts, Adeps Naemorhedi 26 parts, Radix decaisneae fargesii 25 parts, Fructus Ilicis Purpureae 7 parts, Herba Saniculae lamelligerae 25 parts and Radix Micromeli Integerrimi 16 parts.

When the dosage form of described Chinese medicine preparation is granule, and it comprises the following steps:

Step one: mixed in described ratio by described raw medicinal material, adds relative to mixture 5～the alcohol of 6 times Concentration is the ethanol of 80%～95%, is heated to boiling reflux 4～6 hours, filters, is molten with backflow Agent, with filtering residue as solute, uses percolation with the speed slowly percolation of per minute 1～2ml, collects percolation Liquid, when being evaporated to 50～60 DEG C subsequently under vacuum 0.06～0.08Mpa, relative density is The mastic of 1.05～1.10, is spray-dried, and the inlet temperature 160 of spray dryer～175 DEG C, goes out pathogenic wind-warm Spend 80～85 DEG C, be ground into powder subsequently, make dried cream powder；

Step 2: add relative to dried cream powder quality 0.2～the cane sugar powder of 0.4 times in the dried cream powder obtained With the dextrin of 0.1～0.2 times, make granule, be dried in 40～50 DEG C, it is thus achieved that granule.

When the dosage form of described Chinese medicine preparation is tablet, and it comprises the following steps:

The first step, by Rhizoma Smilacis, Folium Neocinnamomi Delavayi, Herba Corallodisci Flabellati, Radix Tetrastigmatis Glabri, Primula szechuanica, grass Radix Angelicae Pubescentis, cattle Milk slurry root, Radix Oenotherae erythrosepalae, Herba Boehmeriae platyphllae, Yunnan Rhizoma Et Radix Notopterygii and Cortex Corni macrophyllae are mixed in proportion, and add relative to mixture 3 Times～alcohol reflux that 5 times amount determining alcohols are 55%～65% 2 times～4 times, each 2 hours～3 Hour, to filter, filtrate merges, and reclaims ethanol, and being concentrated into 70 DEG C of relative densities is 1.30～1.32 Mastic, standby；

Second step, is mixed in proportion surplus stock medical material, adds relative to mixture 3～5 times amount water, boils Boil 2～4 hours, filter, be concentrated into the mastic that 70 DEG C of relative densities are 1.27～1.29；

3rd step, the mastic mixing that the first step, second step are obtained, 55 DEG C～65 DEG C of reduced vacuum are dried, Get dry extract powder；

4th step, carries out mixing process by described dried cream powder and starch, obtains mastic mixture；Described Mastic and the weight ratio of starch be 1: 0.01～0.02；Described mastic mixture is carried out pelletization treatment, Dried, the mastic compound particles obtained；

5th step, is carried out at mixing successively by described mastic compound particles and Pulvis Talci, magnesium stearate Reason, tabletting process, Cotton seeds, obtain Chinese medicine preparation tablet finished product；Described granule, Pulvis Talci, The weight ratio of magnesium stearate is 100: 1～3: 0.15～0.3.

Hereinafter use embodiment to describe embodiments of the present invention in detail, whereby how the present invention is applied Technological means solves technical problem, and the process that realizes reaching technique effect can fully understand and real according to this Execute.

Embodiment 1: granule prepared by the present invention

Take Rhizoma Smilacis 160g, Folium Neocinnamomi Delavayi 350g, Herba Corallodisci Flabellati 120g, Radix Tetrastigmatis Glabri 210g, Primula szechuanica 150g, Grass Radix Angelicae Pubescentis 310g, Radix Fici beecheyanae 150g, Radix Oenotherae erythrosepalae 320g, Herba Boehmeriae platyphllae 190g, Yunnan Rhizoma Et Radix Notopterygii 260g, fourth Coated split leather 200g, Herba Lysionoti Pauciflori 210g, Herba Bulbophylli Odoratissim 100g, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 150g, Adeps Naemorhedi 260g, Radix decaisneae fargesii 250g, Fructus Ilicis Purpureae 70g, Herba Saniculae lamelligerae 250g and Radix Micromeli Integerrimi 160g.

Its preparation method comprises the following steps:

Step one: mixed in described ratio by described raw medicinal material, add relative to 5 times of mixture is pure and strong Degree is the ethanol of 85%, is heated to boiling reflux 5 hours, filters, with backflow as solvent, with filtering residue For solute, use percolation with the speed slowly percolation of 2ml per minute, collect percolate, subsequently very Being evaporated to relative density when 55 DEG C under reciprocal of duty cycle 0.08Mpa is the mastic of 1.05, is spray-dried, spray The inlet temperature of mist drying machine 165 DEG C, leaving air temp 85 DEG C, be ground into powder subsequently, make dried cream powder；

Step 2: obtain dried cream powder in add relative to dried cream powder quality 0.32 times cane sugar powder and The dextrin of 0.17 times, makes granule, is dried in 45 DEG C, it is thus achieved that granule.

Embodiment 2: tablet prepared by the present invention

Take Rhizoma Smilacis 190g, Folium Neocinnamomi Delavayi 310g, Herba Corallodisci Flabellati 150g, Radix Tetrastigmatis Glabri 230g, Primula szechuanica 120g, Grass Radix Angelicae Pubescentis 340g, Radix Fici beecheyanae 120g, Radix Oenotherae erythrosepalae 350g, Herba Boehmeriae platyphllae 160g, Yunnan Rhizoma Et Radix Notopterygii 290g, fourth Coated split leather 170g, Herba Lysionoti Pauciflori 230g, Herba Bulbophylli Odoratissim 70g, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 120g, Adeps Naemorhedi 290g, Radix decaisneae fargesii 220g, Fructus Ilicis Purpureae 90g, Herba Saniculae lamelligerae 210g and Radix Micromeli Integerrimi 190g.

Its preparation method comprises the following steps:

The first step, by Rhizoma Smilacis, Folium Neocinnamomi Delavayi, Herba Corallodisci Flabellati, Radix Tetrastigmatis Glabri, Primula szechuanica, grass Radix Angelicae Pubescentis, cattle Milk slurry root, Radix Oenotherae erythrosepalae, Herba Boehmeriae platyphllae, Yunnan Rhizoma Et Radix Notopterygii and Cortex Corni macrophyllae are mixed in proportion, and add relative to mixture 5 Times amount determining alcohol is the alcohol reflux 2 of 65%, each 3 hours, filters, and filtrate merges, and reclaims second Alcohol, being concentrated into 70 DEG C of relative densities is the mastic of 1.30, standby；

Second step, is mixed in proportion surplus stock medical material, adds relative to mixture 4 times amount water, boils 4 hours, filtering, being concentrated into 70 DEG C of relative densities is the mastic of 1.29；

3rd step, the mastic mixing first step, second step obtained, 55 DEG C of reduced vacuum are dried, and obtain dry Cream powder；

4th step, carries out mixing process by described dried cream powder and starch, obtains mastic mixture；Described Mastic and the weight ratio of starch be 1: 0.02；Described mastic mixture is carried out pelletization treatment, is dried Process, the mastic compound particles obtained；

5th step, is carried out at mixing successively by described mastic compound particles and Pulvis Talci, magnesium stearate Reason, tabletting process, Cotton seeds, obtain Chinese medicine preparation tablet finished product；Described granule, Pulvis Talci, The weight ratio of magnesium stearate is 100: 2.5: 0.25.

Toxicity test:

Acute toxicity testing: application mice 60, male and female half and half, body weight 20-40g, carries out acute poison Property test.Mice is randomly divided into two groups, i.e. matched group and administration group, fasting 12 hours before experiment, incite somebody to action this The Chinese medicine granules of inventive embodiment 1 preparation is dissolved in water, (concentration is 8.63g crude drug/ml, High concentration) gavage, gavage volume is 5ml/kg (i.e. unit dosage form is 43.15 crude drugs/kg), Matched group gives normal saline, within one day, is administered 2 times, delivery time 6 hours, connects after administration Continuous observe 14 days, and record mice toxic reaction and death toll.Test result indicate that: with matched group Relatively, after administration, mice has no notable difference, experiment Continuous Observation 14 days, mouse systemic situation, diet, Drinking-water, body weight increase the most normal.Granule LD50 > 43.15 crude drugs/the kg of the Mouse oral gavage present invention, Every day, maximum dosage-feeding was 86.3 crude drugs/kg/ day.The Chinese medicine clinical application amount of the present invention is 8.35g crude drug / day/people, adult's body weight is in terms of 60KG, and average dosage is 0.139g crude drug/kg/ day.By body weight Meter: the dosis tolerata of the Chinese medicine of mice (average weight is in terms of 30g) the oral administration gavage present invention is as quantity 621 times.Therefore the Chinese medicine acute toxicity of the present invention is extremely low, clinical drug safety.

Long term toxicity test: three groups of mices (often group 20) are pressed by Chinese medicine embodiment 1 granule of the present invention 14.23,27.41 and 41.39g crude drugs/kg continuous use 15 weeks (1.0ml/100g body weight, every day 2 Secondary) and drug withdrawal 3 weeks after, result shows: Chinese medicine of the present invention is to the hair of mice, behavior, defecation, body The indexs such as weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat all have no significant effect, internal organs meat Eye does not find that difference change and histological indications show, after medication 15 weeks and drug withdrawal 3 weeks, and mice Each internal organs are all without substantially changing.Illustrate that Chinese medicine of the present invention is little, after drug withdrawal also to toxicity after mice long-term prescription There is no difference reaction, application safety.

Clinical data:

Case selection: all 126 example cases derive from this Out-patient Department and the calcaneodynia patient being in hospital.Will Patient is randomly divided into two groups, treatment group and each 63 examples of matched group.In treatment group 63 example, male 34 examples, female 29 examples, age 26～73 years old, year mean age (46.3 ± 4.6)；The course of disease 1～5 years, average (2.43 ± 1.2) year；Left foot 33 example, right foot 19 example, biped 11 example.In matched group 63 example, male 33 examples, Female 30 example, age 27～71 years old, year mean age (45.7 ± 3.7)；The course of disease 1～4 years, averagely (2.27 ± 1.5) year；Left foot 32 example, right foot 20 example, biped 11 example.Treatment group and matched group exist The aspects such as sex, age, the course of disease, site of pathological change and clinical symptoms compare no significant difference, have comparable Property.

Diagnostic criteria: 1, with end pain, function limitation, difficulty in walking；2, have a medical check-up with at the end or calcaneus Local tenderness point or full heel is had to have tenderness at lateral condyle；3, X-ray film shows with the end is with or without bony spur sample Proliferation；4, the calcaneodynia pathological changes that eliminating bone tuberculosis, infection of bone, bone tumor cause.

Therapeutic Method:

Matched group: application HK ESWO-AJ shock-wave therapeutic machine is treated, running voltage 6～9KV, Every Secondary Shocks 800～1000 times, treatment interval 7 days, treatment sum 3～4 times, measuring blood pressure before treatment, Pulse, body temperature etc., inquire relevant medical history, it is ensured that patient is without treatment contraindication.Rest 30～60min after treatment Without leaving after special discomfort, and exhort that patient lies up more.

Treatment group: on the basis for the treatment of of control group, is administered orally Chinese medicine embodiment 1 granule of the present invention simultaneously, 20g every time, three times a day；Within 7 days, it is a course for the treatment of, after four courses for the treatment of, adds up therapeutic outcome.

Curative effect judging standard: visual simulation rating method (Visual Analog Scale, VAS) evaluation pain Degree bitterly.(1) recovery from illness: symptom, sign are wholly absent, extensive recovery operation, VAS marks≤1 point, VAS weighted value^{[(A-B)/A × 100%]}>=75%.(2) effective: symptom major part disappears, and can resume work, labor Having slight discomfort after Lei, VAS marks≤3 points, VAS weighted value 50%～75%.(3) effective: clinical Symptom is improved, and VAS marks ＞ 3 points, but more preoperative minimizing more than 3 points, VAS weighted value 25%～50%. (4) invalid: symptom and sign is without improving, and the VAS more preoperative minimizing of scoring is inconspicuous, VAS weighted value ＜ 25%.

Therapeutic outcome: after two groups are treated 28 days respectively, statistical result sees table 1.

Clinical efficacy comparison (unit: example) after treating 28 days respectively organized by 1 liang of table

Group	Number of cases	Recovery from illness	Effective	Effectively	Invalid	Total effective rate
							Treatment group	63	43	9	8	3	60 (95.24%)
Matched group	63	32	11	9	11	52 (82.54%)

As it can be seen from table 1 treatment group uses the Chinese medicine of the present invention, coordinate western medical treatment calcaneodynia, phase For matched group, on therapeutic effect, have and be markedly improved.

Untoward reaction: matched group patient, during treating, hepatic and renal function injure, gastrointestinal tract does not all occur not Fit or other untoward reaction.

Concrete case: Chen, man, 67 years old, patient's private prosecution right heel portion pain March, sitting stand and Bearing a heavy burden when walking, the pain increased, and local is normal without swelling, color of the leather.In pressing right heel portion, front side pain is bright Aobvious, light red tongue, white and thin fur, thready pulse.X-ray photo calcaneus has no that calcanean spur is formed, and examines through clinic It is diagnosed as calcaneodynia.Take western medical treatment, the granule of inventive embodiments 1 be administered orally simultaneously, each 20g, Three times a day.After treating the 20th day, the clinical symptom disappearance such as heel portion pain, walking is normal, cures, Follow up a case by regular visits to 3 months without recurrence.

All above-mentioned primary implement these intellectual properties, do not set limit other forms enforcement this Plant new product or new method.Those skilled in the art will utilize this important information, and foregoing is revised, To realize similar implementation status.But, all modifications or transformation belong to reservation based on new product of the present invention Right.

The above, be only presently preferred embodiments of the present invention, is not that the present invention makees other form Restriction, any those skilled in the art are changed possibly also with the technology contents of the disclosure above Or it is modified as the Equivalent embodiments of equivalent variations.But every without departing from technical solution of the present invention content, depend on Any simple modification, equivalent variations and remodeling above example made according to the technical spirit of the present invention, Still fall within the protection domain of technical solution of the present invention.

Claims (8)

1. the Chinese medicine preparation treating calcaneodynia, it is characterised in that described Chinese medicine preparation includes following former Material medical material: Rhizoma Smilacis, Folium Neocinnamomi Delavayi, Herba Corallodisci Flabellati, Radix Tetrastigmatis Glabri, Primula szechuanica, grass Radix Angelicae Pubescentis, Radix Fici beecheyanae, Radix Oenotherae erythrosepalae, Herba Boehmeriae platyphllae, Yunnan Rhizoma Et Radix Notopterygii, Cortex Corni macrophyllae, Herba Lysionoti Pauciflori, Herba Bulbophylli Odoratissim, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep., Adeps Naemorhedi, cat Dung, Fructus Ilicis Purpureae, Herba Saniculae lamelligerae and Radix Micromeli Integerrimi.

2. Chinese medicine preparation as claimed in claim 1, it is characterised in that the weight portion of described raw medicinal material Number ratio is: Rhizoma Smilacis 15～25 parts, Folium Neocinnamomi Delavayi 30～40 parts, Herba Corallodisci Flabellati 5～15 parts, Radix Tetrastigmatis Glabri 15～30 parts, Primula szechuanica 10～20 parts, grass Radix Angelicae Pubescentis 25～35 parts, Radix Fici beecheyanae 5～15 part, month are seen Grass 30～40 parts, Herba Boehmeriae platyphllae 15～25 parts, Yunnan Rhizoma Et Radix Notopterygii 20～30 parts, Cortex Corni macrophyllae 10～20 parts, stone Bracketplant 15～30 parts, Herba Bulbophylli Odoratissim 5～15 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 10～20 parts, Adeps Naemorhedi 25～35 parts, cat Dung 15～30 parts, Fructus Ilicis Purpureae 5～15 parts, Herba Saniculae lamelligerae 20～30 parts and Radix Micromeli Integerrimi 15～25 parts.

3. Chinese medicine preparation as claimed in claim 1 or 2, it is characterised in that the weight of described raw medicinal material Amount portion rate is: Rhizoma Smilacis 15～20 parts, Folium Neocinnamomi Delavayi 30～35 parts, Herba Corallodisci Flabellati 10～15 parts, little by nine Joint bell 20～25 parts, Primula szechuanica 10～15 parts, grass Radix Angelicae Pubescentis 30～35 parts, Radix Fici beecheyanae 10～15 parts, Radix Oenotherae erythrosepalae 30～35 parts, Herba Boehmeriae platyphllae 15～20 parts, Yunnan Rhizoma Et Radix Notopterygii 25～30 parts, Cortex Corni macrophyllae 15～20 parts, Herba Lysionoti Pauciflori 20～25 parts, Herba Bulbophylli Odoratissim 5～10 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 10～15 parts, Adeps Naemorhedi 25～30 parts, cat Youngster's dung 20～25 parts, Fructus Ilicis Purpureae 5～10 parts, Herba Saniculae lamelligerae 20～25 parts and Radix Micromeli Integerrimi 15～20 parts.

4. the Chinese medicine preparation as described in claims 1 to 3, it is characterised in that the weight of described raw medicinal material Amount portion rate be: Rhizoma Smilacis 16 parts, Folium Neocinnamomi Delavayi 35 parts, Herba Corallodisci Flabellati 12 parts, Radix Tetrastigmatis Glabri 21 parts, Primula szechuanica 15 parts, grass Radix Angelicae Pubescentis 31 parts, Radix Fici beecheyanae 15 parts, Radix Oenotherae erythrosepalae 32 parts, Herba Boehmeriae platyphllae 19 parts, Yunnan Rhizoma Et Radix Notopterygii 26 parts, Cortex Corni macrophyllae 20 parts, Herba Lysionoti Pauciflori 21 parts, Herba Bulbophylli Odoratissim 10 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 15 parts, goat Oil 26 parts, Radix decaisneae fargesii 25 parts, Fructus Ilicis Purpureae 7 parts, Herba Saniculae lamelligerae 25 parts and Radix Micromeli Integerrimi 16 parts.

5. the Chinese medicine preparation as described in Claims 1-4, it is characterised in that the agent of described Chinese medicine preparation Type is granule, and its preparation method comprises the following steps:

Step one: mixed in described ratio by described raw medicinal material, adds relative to mixture 5～the alcohol of 6 times Concentration is the ethanol of 80%～95%, is heated to boiling reflux 4～6 hours, filters, is molten with backflow Agent, with filtering residue as solute, uses percolation with the speed slowly percolation of per minute 1～2ml, collects percolation Liquid, when being evaporated to 50～60 DEG C subsequently under vacuum 0.06～0.08Mpa, relative density is The mastic of 1.05～1.10, is spray-dried, and the inlet temperature 160 of spray dryer～175 DEG C, goes out pathogenic wind-warm Spend 80～85 DEG C, be ground into powder subsequently, make dried cream powder；

Step 2: add relative to dried cream powder quality 0.2～the cane sugar powder of 0.4 times in the dried cream powder obtained With the dextrin of 0.1～0.2 times, make granule, be dried in 40～50 DEG C, it is thus achieved that granule.

6. the Chinese medicine preparation as described in Claims 1-4, it is characterised in that the agent of described Chinese medicine preparation Type is tablet, and its preparation method comprises the following steps:

The first step, by Rhizoma Smilacis, Folium Neocinnamomi Delavayi, Herba Corallodisci Flabellati, Radix Tetrastigmatis Glabri, Primula szechuanica, grass Radix Angelicae Pubescentis, cattle Milk slurry root, Radix Oenotherae erythrosepalae, Herba Boehmeriae platyphllae, Yunnan Rhizoma Et Radix Notopterygii and Cortex Corni macrophyllae are mixed in proportion, and add relative to mixture 3 Times～alcohol reflux that 5 times amount determining alcohols are 55%～65% 2 times～4 times, each 2 hours～3 Hour, to filter, filtrate merges, and reclaims ethanol, and being concentrated into 70 DEG C of relative densities is 1.30～1.32 Mastic, standby；

Second step, is mixed in proportion surplus stock medical material, adds relative to mixture 3～5 times amount water, boils Boil 2～4 hours, filter, be concentrated into the mastic that 70 DEG C of relative densities are 1.27～1.29；

3rd step, the mastic mixing that the first step, second step are obtained, 55 DEG C～65 DEG C of reduced vacuum are dried, Get dry extract powder；

4th step, carries out mixing process by described dried cream powder and starch, obtains mastic mixture；Described Mastic and the weight ratio of starch be 1: 0.01～0.02；Described mastic mixture is carried out pelletization treatment, Dried, the mastic compound particles obtained；

5th step, is carried out at mixing successively by described mastic compound particles and Pulvis Talci, magnesium stearate Reason, tabletting process, Cotton seeds, obtain Chinese medicine preparation tablet finished product；Described granule, Pulvis Talci, The weight ratio of magnesium stearate is 100: 1～3: 0.15～0.3.

7. the preparation method of the Chinese medicine preparation described in a Claims 1-4, it is characterised in that described The dosage form of Chinese medicine preparation is granule, and it comprises the following steps:

Step one: mixed in described ratio by described raw medicinal material, adds relative to mixture 5～the alcohol of 6 times Concentration is the ethanol of 80%～95%, is heated to boiling reflux 4～6 hours, filters, is molten with backflow Agent, with filtering residue as solute, uses percolation with the speed slowly percolation of per minute 1～2ml, collects percolation Liquid, when being evaporated to 50～60 DEG C subsequently under vacuum 0.06～0.08Mpa, relative density is The mastic of 1.05～1.10, is spray-dried, and the inlet temperature 160 of spray dryer～175 DEG C, goes out pathogenic wind-warm Spend 80～85 DEG C, be ground into powder subsequently, make dried cream powder；

Step 2: add relative to dried cream powder quality 0.2～the cane sugar powder of 0.4 times in the dried cream powder obtained With the dextrin of 0.1～0.2 times, make granule, be dried in 40～50 DEG C, it is thus achieved that granule.

8. the preparation method of the Chinese medicine preparation described in a Claims 1-4, it is characterised in that described The dosage form of Chinese medicine preparation is tablet, and its preparation method comprises the following steps:

The first step, by Rhizoma Smilacis, Folium Neocinnamomi Delavayi, Herba Corallodisci Flabellati, Radix Tetrastigmatis Glabri, Primula szechuanica, grass Radix Angelicae Pubescentis, cattle Milk slurry root, Radix Oenotherae erythrosepalae, Herba Boehmeriae platyphllae, Yunnan Rhizoma Et Radix Notopterygii and Cortex Corni macrophyllae are mixed in proportion, and add relative to mixture 3 Times～alcohol reflux that 5 times amount determining alcohols are 55%～65% 2 times～4 times, each 2 hours～3 Hour, to filter, filtrate merges, and reclaims ethanol, and being concentrated into 70 DEG C of relative densities is 1.30～1.32 Mastic, standby；

Second step, is mixed in proportion surplus stock medical material, adds relative to mixture 3～5 times amount water, boils Boil 2～4 hours, filter, be concentrated into the mastic that 70 DEG C of relative densities are 1.27～1.29；

3rd step, the mastic mixing that the first step, second step are obtained, 55 DEG C～65 DEG C of reduced vacuum are dried, Get dry extract powder；

4th step, carries out mixing process by described dried cream powder and starch, obtains mastic mixture；Described Mastic and the weight ratio of starch be 1: 0.01～0.02；Described mastic mixture is carried out pelletization treatment, Dried, the mastic compound particles obtained；

5th step, is carried out at mixing successively by described mastic compound particles and Pulvis Talci, magnesium stearate Reason, tabletting process, Cotton seeds, obtain Chinese medicine preparation tablet finished product；Described granule, Pulvis Talci, The weight ratio of magnesium stearate is 100: 1～3: 0.15～0.3.