CN105997951A - 一种包含卡巴拉汀的透皮给药系统及制备方法 - Google Patents
一种包含卡巴拉汀的透皮给药系统及制备方法 Download PDFInfo
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- CN105997951A CN105997951A CN201610411017.5A CN201610411017A CN105997951A CN 105997951 A CN105997951 A CN 105997951A CN 201610411017 A CN201610411017 A CN 201610411017A CN 105997951 A CN105997951 A CN 105997951A
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- Prior art keywords
- rivastigmine
- acid
- drug delivery
- transdermal drug
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- GDSOZVZXVXTJMI-SNAWJCMRSA-N (e)-1-methylbut-1-ene-1,2,4-tricarboxylic acid Chemical compound OC(=O)C(/C)=C(C(O)=O)\CCC(O)=O GDSOZVZXVXTJMI-SNAWJCMRSA-N 0.000 description 1
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- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
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- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
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- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (46)
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CN201610411017.5A CN105997951B (zh) | 2016-06-12 | 2016-06-12 | 一种包含卡巴拉汀的透皮给药系统及制备方法 |
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Cited By (7)
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CN107929267A (zh) * | 2017-12-01 | 2018-04-20 | 安徽安科余良卿药业有限公司 | 卡巴拉汀透皮贴剂及其制备方法 |
CN107951863A (zh) * | 2016-10-14 | 2018-04-24 | 北京泰德制药股份有限公司 | 一种含有卡巴拉汀及其药用盐的皮肤外用制剂及其制备方法 |
CN108926549A (zh) * | 2018-09-27 | 2018-12-04 | 安徽安科余良卿药业有限公司 | 卡巴拉汀凝胶贴膏及其制备方法 |
JP2019026608A (ja) * | 2017-08-01 | 2019-02-21 | 久光製薬株式会社 | 貼付剤 |
CN110642751A (zh) * | 2016-03-01 | 2020-01-03 | 巴斯特医药科技(常州)有限公司 | 卡巴拉汀盐处理方法及透皮给药贴剂 |
CN111093639A (zh) * | 2017-09-05 | 2020-05-01 | 罗曼治疗系统股份公司 | 用于卡巴拉汀经皮给药的经皮治疗系统 |
CN111195242A (zh) * | 2018-11-16 | 2020-05-26 | 得生制药股份有限公司 | 经皮吸收贴片 |
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CN110642751A (zh) * | 2016-03-01 | 2020-01-03 | 巴斯特医药科技(常州)有限公司 | 卡巴拉汀盐处理方法及透皮给药贴剂 |
CN107951863A (zh) * | 2016-10-14 | 2018-04-24 | 北京泰德制药股份有限公司 | 一种含有卡巴拉汀及其药用盐的皮肤外用制剂及其制备方法 |
CN107951863B (zh) * | 2016-10-14 | 2020-05-12 | 北京泰德制药股份有限公司 | 一种含有卡巴拉汀及其药用盐的皮肤外用制剂及其制备方法 |
JP2019026608A (ja) * | 2017-08-01 | 2019-02-21 | 久光製薬株式会社 | 貼付剤 |
JP7029244B2 (ja) | 2017-08-01 | 2022-03-03 | 久光製薬株式会社 | 貼付剤 |
CN111093639A (zh) * | 2017-09-05 | 2020-05-01 | 罗曼治疗系统股份公司 | 用于卡巴拉汀经皮给药的经皮治疗系统 |
CN107929267A (zh) * | 2017-12-01 | 2018-04-20 | 安徽安科余良卿药业有限公司 | 卡巴拉汀透皮贴剂及其制备方法 |
CN108926549A (zh) * | 2018-09-27 | 2018-12-04 | 安徽安科余良卿药业有限公司 | 卡巴拉汀凝胶贴膏及其制备方法 |
CN111195242A (zh) * | 2018-11-16 | 2020-05-26 | 得生制药股份有限公司 | 经皮吸收贴片 |
CN111195242B (zh) * | 2018-11-16 | 2022-10-25 | 得生制药股份有限公司 | 经皮吸收贴片 |
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Address after: Room 116, Floor 1, Transportation Bureau Building, No. 95, Yingbin Avenue, Huacheng Street, Huadu District, Guangzhou, Guangdong Province, 510801 Patentee after: Guangzhou Iconas Biomedical Technology Co.,Ltd. Patentee after: Yang Mingjing Address before: 515063 in Rongsheng science and Technology Park, University Road, Shantou City, Guangdong Province Patentee before: RUNBIO BIOTECH Co.,Ltd. Patentee before: Yang Mingjing |
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Correction item: Patentee|Address|Patentee Correct: RUNBIO BIOTECH Co.,Ltd.|515063 in Rongsheng science and Technology Park, University Road, Shantou City, Guangdong Province|Yang Mingjing False: Guangzhou Iconas Biomedical Technology Co.,Ltd.|Room 116, Floor 1, Transportation Bureau Building, No. 95, Yingbin Avenue, Huacheng Street, Huadu District, Guangzhou, Guangdong Province, 510801|Yang Mingjing Number: 10-02 Volume: 39 |
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Address after: Room 116, Floor 1, Transportation Bureau Building, No. 95, Yingbin Avenue, Huacheng Street, Huadu District, Guangzhou, Guangdong Province, 510801 Patentee after: Guangdong Iconas Biomedical Technology Co.,Ltd. Patentee after: Yang Mingjing Address before: Room 116, Floor 1, Transportation Bureau Building, No. 95, Yingbin Avenue, Huacheng Street, Huadu District, Guangzhou, Guangdong Province, 510801 Patentee before: Guangdong Iconas Biomedical Technology Co.,Ltd. Patentee before: Yang Mingjing |
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Address after: Room 116, Floor 1, Transportation Bureau Building, No. 95, Yingbin Avenue, Huacheng Street, Huadu District, Guangzhou, Guangdong Province, 510801 Patentee after: Guangdong Iconas Biomedical Technology Co.,Ltd. Patentee after: Yang Mingjing Address before: 515063 in Rongsheng science and Technology Park, University Road, Shantou City, Guangdong Province Patentee before: RUNBIO BIOTECH Co.,Ltd. Patentee before: Yang Mingjing |