CN105997780A

CN105997780A - Cosmetic for reducing fine wrinkles and tightening face

Info

Publication number: CN105997780A
Application number: CN201610335980.XA
Authority: CN
Inventors: 秦瑜
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-05-20
Filing date: 2016-05-20
Publication date: 2016-10-12

Abstract

The invention discloses a cosmetic for reducing fine wrinkles and tightening the face. The cosmetic is prepared from, by weight parts, 0.4-0.6 part of vitamin B3, 0.5-0.6 part of xanthan gum, 0.3-0.4 part of 2-bromo-2-nitro-1,3-propandiol, 20-25 parts of milk thistle, 33-37 parts of dendrobium officinale, 10-13 parts of protea cynaroides, 16-20 parts of cranberry, 40-50 parts of discarded hair, 13-15 parts of shell powder, 3-4 parts of glyceryl monostearate, 0.5-1 part of allicin, 2-3 parts of jojoba oil, 5-7 parts of sweet almond oil, 18-22 parts of freeze-drying carrot powder, 8-12 parts of lotus leaf powder, 0.5-0.6 part of xanthan gum, 2-3 parts of dicaprylyl carbonate, 0.5-0.6 part of coco-glucoside, 1-2 parts of inulin and 55-65 parts of water. The cosmetic has effects of flattening the fine wrinkles, moistening cells, recovering skin elasticity, improving loose and coarse skin, creating smooth and tender skin and presenting shining lustre.

Description

A kind of microgroove that reduces lifts the face cosmetic that compacts

Technical field

The present invention relates to technical field of skin care, particularly relate to a kind of microgroove that reduces and lift the face cosmetic that compacts.

Background technology

In recent years, along with expanding economy and growth in the living standard, people increasingly pay attention to the maintenance of skin, so that cosmetics quickly grow.Having and beautify and treat double effects, character causes between the functional type cosmetics of cosmetics and medicine and pays close attention to widely.Unlike Traditional makeup, functional type cosmetics should make functional components pass through horny layer as far as possible, and lasting plays nutrition, protection or therapeutical effect, less entrance blood circulation, thus improve effect local organization and cell.The method of searching promotion functions composition percutaneous absorbtion is one of key of these type of cosmetics of R and D.The skin of people is the cellularity fine and close by a layer, and cell membrane is impermeable to macromole bioactive substance.Active component nutrition to be reached in cosmetics, improve skin and effect of prevention dermatosis, it is important to active substance must be transmitted through horny layer and reaches corresponding site of action and maintain certain time.Liposome is the completely enclosed multilamellar vesicle of the bilayer formed by lipoids such as phospholipid, it is similar to that cell, water solublity and fat-soluble two kinds of materials can be encapsulated, have that targeting is efficient, slow release is controlled and the feature of safety non-toxic, but a lot of problem can be there is in liposome solutions long term storage, the seepage of such as active substance, the gathering of liposome particles and phospholipid are the most oxidized etc. under liquid condition, and these problems limit liposome application in cosmetics.

Liao Jinyan is studied mainly for ginseng aqueous extract liposome in " research of liposomal encapsulated Radix Ginseng extractive solution and the application in cosmetics thereof " literary composition, at the content measuring Radix Ginseng aqueous extract Radix Ginseng total saponins, on the basis of determining entrapment efficiency determination method and method for preparing lipidosome, Radix Ginseng aqueous extract liposome application performance in cosmetics is studied, and the particle diameter of liposome is calculated, all within 600nm, illustrate that liposome can readily penetrate skin for cosmetics, but liposome belongs to fine dispersion system, it it is thermodynamic unstable system, do not possesses good shelf characteric, period of storage length is easily subject to temperature, illumination, size, the interference of the factors such as envelop rate, thus largely effect on the character of cosmetics.The present invention, in order to ensure the stability in liposome long term storage, is prepared as freeze-dried lipidosome dosage form in conjunction with Freeze Drying Technique and is greatly improved stability, improve the quality of cosmetics.

Summary of the invention

The object of the invention is contemplated to make up the defect of prior art, it is provided that a kind of microgroove that reduces lifts the face cosmetic that compacts.

The present invention is achieved by the following technical solutions:

A kind of microgroove that reduces lifts the face cosmetic that compacts, it is made up of the raw material of following weight portion: vitamin B3 0.4-0.6, xanthan gum 0.5-0.6, 2-bromo-2-nitro-1, ammediol 0.3-0.4, Milk Thistle 20-25, Herba Dendrobii flower 33-37, Tilia europaea 10-13, cranberry 16-20, discarded hair 40-50, conch meal 13-15, glyceryl monostearate 3-4, garlicin 0.5-1, Jojoba oil 2-3, Semen pruni armeniacae oil 5-7, lyophilizing Radix Dauci Sativae powder 18-22, Folium Nelumbinis powder 8-12, xanthan gum 0.5-0.6, dicaprylyl carbonate 2-3, Coco-Glucoside 0.5-0.6, inulin 1-2, water 55-65.

Described a kind of microgroove that reduces lifts the face cosmetic that compacts, and is made up of step in detail below:

(1) by after Milk Thistle, Herba Dendrobii flower, Tilia europaea and cranberry co-grinding, heating extraction 1.5-2h in 75% ethanol solution, centrifugation is carried out after being cooled to room temperature, centrifugal speed is 4000-5000rpm, and centrifugation time is 10-20min, then takes its supernatant and carries out fine straining, filtrate after fine straining is concentrated to give extractum, again extractum propylene glycol is dissolved, filter, obtain the extracting solution that content is 10mg/ml standby；

(2) by discarded hair, conch meal cleans after drying and lyophilizing Radix Dauci Sativae powder, Folium Nelumbinis powder mixing add zymocyte and ferment, fermentation temperature is 36-45 DEG C, time is 12-15h, gained fermentation liquid is carried out sterilizing again and is centrifuged, centrifugal rotational speed is 8000-12000r/min, centrifugation time is 10-20min, then collects supernatant standby；

(3) soybean lecithin, 18-amine. and cholesterol are mixed, with appropriate ether dissolution mixture, after all dissolving on Rotary Evaporators 30-35 DEG C be evaporated film forming, then take product 3.5-5ml prepared by step (1), product 2.5-4ml prepared by step (2) and appropriate pH value are the PBS of 6.8, Tween 80 and sorbester p17 is added after stirring, in ice bath, ultrasonic emulsification 40-50min obtains suspension, carry out lyophilization by suspension adding after inulin stirs, obtain lipidosome freeze-dried powder standby；

(4) Jojoba oil, Semen pruni armeniacae oil, glyceryl monostearate and Coco-Glucoside are mixed and heated to 70-75 DEG C, add glycerol, xanthan gum and water homogenisation stirring 30-35min, it is cooled to when 30-40 DEG C add remaining surplus materials stir, product prepared by step (3) is added after being cooled to room temperature, quality inspection after stirring, discharging, packs.

nullThe invention have the advantage that the present invention utilizes Milk Thistle、Herba Dendrobii flower、Tilia europaea and cranberry cooperate and use alcohol extraction to go out to have maintenance Skin Cell、Reduce endotoxins on cells infringement、Also can remove free radical、Convergence、Soft skin、Antiinflammatory、Infection、The effective ingredient of the good natural cover for defense is set up for skin，Also by discarded hair、Conch meal and lyophilizing Radix Dauci Sativae powder、Folium Nelumbinis powder hydrolysis fermentation together goes out multiple beneficial composition，Nutrition is provided for skin，And nutrition can be injected for skin，Delaying cell aging，Resist various radiation、The ultraviolet injury to skin，Skin care，Reduce the effect of microgroove，By both effective ingredient with liposomal encapsulated，And the 18-amine. added makes surface of liposome positively charged，The most electronegative Skin Cell compatibility is good，Good penetrability，Its bin stability is increased also by cryodesiccated method，Improve the stability of cosmetics，The cosmetics of the present invention have to put down comforts microgroove、Moisten cellular-restoring elasticity of skin、Improve cutis laxa、Coarse effect，Create smooth tender skin，Present the brilliance that glitters.

Detailed description of the invention

A kind of microgroove that reduces lifts the face cosmetic that compacts, be made up of the raw material of following weight portion (kilogram): vitamin B3 0.4, xanthan gum 0.5,2 bromine nitro, 3 propylene glycol 0.3, Milk Thistle 20, Herba Dendrobii spend 33, Tilia europaea 10, cranberry 16, discarded hair 40, conch meal 13, glyceryl monostearate 3, garlicin 0.5, Jojoba oil 2, Semen pruni armeniacae oil 5, lyophilizing Radix Dauci Sativae powder 18, Folium Nelumbinis powder 8, xanthan gum 0.5, dicaprylyl carbonate 2, Coco-Glucoside 0.5, inulin 1, water 55.

(1) by after Milk Thistle, Herba Dendrobii flower, Tilia europaea and cranberry co-grinding, heating extraction 1.5h in 75% ethanol solution, centrifugation is carried out after being cooled to room temperature, centrifugal speed is 4000rpm, and centrifugation time is 10min, then takes its supernatant and carries out fine straining, filtrate after fine straining is concentrated to give extractum, again extractum propylene glycol is dissolved, filter, obtain the extracting solution that content is 10mg/ml standby；

(2) by discarded hair, conch meal cleans after drying and lyophilizing Radix Dauci Sativae powder, Folium Nelumbinis powder mixing add zymocyte and ferment, fermentation temperature is 36 DEG C, time is 12h, gained fermentation liquid is carried out sterilizing again and is centrifuged, centrifugal rotational speed is 8000r/min, centrifugation time is 10min, then collects supernatant standby；

(3) soybean lecithin, 18-amine. and cholesterol are mixed, with appropriate ether dissolution mixture, after all dissolving on Rotary Evaporators 30 DEG C be evaporated film forming, then take product 3.5ml prepared by step (1), product 2.5ml prepared by step (2) and appropriate pH value are the PBS of 6.8, Tween 80 and sorbester p17 is added after stirring, in ice bath, ultrasonic emulsification 40min obtains suspension, carry out lyophilization by suspension adding after inulin stirs, obtain lipidosome freeze-dried powder standby；

(4) Jojoba oil, Semen pruni armeniacae oil, glyceryl monostearate and Coco-Glucoside are mixed and heated to 70 DEG C, add glycerol, xanthan gum and water homogenisation stirring 30min, it is cooled to when 30 DEG C add remaining surplus materials stir, product prepared by step (3) is added after being cooled to room temperature, quality inspection after stirring, discharging, packs.

Its performance is detected by the cosmetics prepared according to embodiment, and result is as follows:

Thermostability (40 ± 1 DEG C, 24h): without oil-water separation phenomenon after recovery room temperature；Tolerance to cold (-5-10 DEG C, 24h): no significant difference front with test after recovering room temperature；Lead content (mg/Kg): 0.1；Mercury content (mg/Kg): 0.03；Arsenic content (mg/Kg): 0.05: total number of bacteria (CFU/g): ＜ 10；Yeast and mold sum (CFU/g): ＜ 10；Excrement colibacillus group: do not detect；Bacillus pyocyaneus: do not detect；Golden yellow Fructus Vitis viniferae bacillus: do not detect.

Claims

1. a minimizing microgroove lifts the face cosmetic that compacts, it is characterized in that, it is made up of the raw material of following weight portion: vitamin B3 0.4-0.6, xanthan gum 0.5-0.6, 2-bromo-2-nitro-1, ammediol 0.3-0.4, Milk Thistle 20-25, Herba Dendrobii flower 33-37, Tilia europaea 10-13, cranberry 16-20, discarded hair 40-50, conch meal 13-15, glyceryl monostearate 3-4, garlicin 0.5-1, Jojoba oil 2-3, Semen pruni armeniacae oil 5-7, lyophilizing Radix Dauci Sativae powder 18-22, Folium Nelumbinis powder 8-12, xanthan gum 0.5-0.6, dicaprylyl carbonate 2-3, Coco-Glucoside 0.5-0.6, inulin 1-2, water 55-65.

The most according to claim 1, a kind of microgroove that reduces lifts the face cosmetic that compacts, it is characterised in that be made up of step in detail below: