CN105997638A - Traditional Chinese medicine composition containing Fructus Quisqualis and used for acarid-eliminating cosmetics - Google Patents
Traditional Chinese medicine composition containing Fructus Quisqualis and used for acarid-eliminating cosmetics Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition containing Fructus Quisqualis and used for acarid-eliminating cosmetics. The composition is prepared from the following raw materials by weight: 10 to 18 parts of phellodendron bark, 20 to 30 parts of Fructus Quisqualis, 10 to 15 parts of tree peony bark, 6 to 10 parts of divaricate saposhnikovia root, 0.2 to 0.5 part of camphor and 6 to 9 parts of mint. Through optimization of combination of the raw materials, synergistic interaction of the raw materials is realized, so the composition has acarid-eliminating effect; and the composition is composed of purely natural plant extract, mild in drug effect, small in side-effect, wide in application scope and low in cost.
Description
Technical field
The present invention relates to cosmetic field, particularly to a kind of Chinese medicine for acaricide worm cosmetics containing Fructus Quisqualis fruit
Compositions.
Background technology
Acarid belongs to the animal that a class build of Arthropoda Arachnoidea wide abdomen subclass is small, and body size the most all exists
0.5 millimeter, some little to 0.1 millimeter, most of kinds are less than 1 millimeter.It is now discovered that the healthy relation of acarid and people is very
Closely, such as gamasid, trombiculid, acaricide, compacted demodicid mite, flour mite, dust mite and Pu demodicid mite etc. can sting people and suck blood, encroach on skin, causes " distiller grains
Nose " or demodicidosis, anaphylaxis, urinary tract demodicid mite disease, pulmonary acariasis, intestinal acariasis and scabies, the serious harm mankind's is healthy.
Mention acarid, first affirmed the acarid harm to skin, be not as described in some people " acarid is normal bacteria
Group, acaricide does not affects the whole.Acarid is ' worm ', by no means ' flora ' ", it is belonging to the parasite of human of Arthropoda Arachnoidea,
Also it is a lot of harmful levels of pathogens carriers simultaneously.Adult's mite infection rate is the highest, and the skin infecting acarid shows as under normal circumstances
Lighter symptom, such as heavy wool, corse sweat pore are with blackhead, little red pimple or red papules, skin pruritus or decortication etc., severe
The infected can cause demodicid mite property acne rosacea and allergic disease.
Acarid draws nutritional labeling inside skin, stimulates blood capillary and cell tissue, causes cutaneous malignancies.Skin
Acarid accelerates the generation of fine wrinkles, accelerates the pigmentation such as chloasma, freckle, black speck, can also result in acne, pox scar, acne,
Pachylosis, cutin are thickening, form concavo-convex skin.Cutaneous mites can also be formed pruritus, acne rosacea and blush, red blood streak
Deng.
The method of existing acaricide worm has a variety of, has and directly uses compound pesticides to carry out acaricide, acaricide instant effect, but
Big, the most repeatedly to skin harm；Also having employing natural Chinese medicinal herb composition acaricide worm, side effect is little, low price, and can repair damage
Hinder skin histology, but it is slow to there is the speed that takes effect, the defect of weak effect, thus, improving Chinese medicine formula is to remove to improve its drug effect
The optimal path of acarid.
Summary of the invention
It is an object of the invention to overcome the acaricide worm weak effect existing for existing acaricide worm Chinese medicine composition, acaricide worm to see
Imitate slow deficiency, it is provided that a kind of Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit.Said composition is by excellent
Change the compatibility of raw material, make to produce between raw medicinal material synergistic function, add the acaricide worm effect of compositions and the speed that takes effect
Degree, drug effect is gentle；Said composition is combined by pure natural plant extract, and side effect is little, and wide adaptability is with low cost.
In order to realize foregoing invention purpose, the invention provides a kind of containing Fructus Quisqualis fruit for acaricide worm cosmetics
Chinese medicine composition, said composition is to be prepared from by the raw material of following weight: Cortex Phellodendri 10-18 part, Fructus Quisqualis fruit 20-
30 parts, Cortex Moutan 10-15 part, Radix Saposhnikoviae 6-10 part, Camphora 0.2-0.5 part, Herba Menthae 6-9 part.
Above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit, wherein said Cortex Phellodendri, taste
Bitter；Cold in nature；Return kidney, bladder warp；Having heat clearing and damp drying, pathogenic fire purging is except steaming, effect of detoxification sore treatment；It is mainly used in treating damp and hot rushing down
Dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, tinea pedis flaccidity is preesed, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.
Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Wherein said Fructus Quisqualis fruit, for the mature fruit of Combretum Racemosum plant Fructus Quisqualis, sweet in the mouth, warm in nature；Return spleen, stomach
Warp；There is effect of killing insect and eliminating accumulation；It is mainly used in treating ascarid, enterobiasis, abdominal pain due to worm stagnation, infantile malnutrition.
Wherein said Cortex Moutan, bitter in the mouth, pungent；Cold nature；GUIXIN, liver, kidney channel；There is clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling
Effect；It is mainly used in treating thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, falls and flutter wound
Bitterly, carbuncle sore tumefacting virus.
Wherein said Radix Saposhnikoviae, acrid in the mouth, sweet, slightly warm in nature；Return bladder, lung, spleen, Liver Channel；There is expelling pathogenic wind from the body surface, win wet stopping
Bitterly, effect of relieving convulsion, be mainly used in treat diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus just, insufficiency of the spleen leading to overabundance of dampness.
Wherein said Camphora, acrid in the mouth；Property heat；GUIXIN, spleen channel；There is orifice opening, qi stagnation removing, ward off foul, killing parasites for relieving itching,
Effect of reducing swelling and alleviating pain；It is mainly used in treating calentura coma；Attacked by pestiferous factors is dampinged off, and acute filthy disease is vomited and diarrhoea and suffered from abdominal pain；The disturbance of lower legs due to pathogenic cold and dampness；Scabies stubborn dermatitis；
Tinea alba；Chilblain；Ecthyma；Burn due to hot liquid or fire；Traumatic pain；Toothache；Wind-fire acute conjunctivitis.
Wherein said Herba Menthae, acrid in the mouth, cool in nature；Return liver, lung meridian；There is dispelling wind-heat, refresh oneself, effect of rash；Main
Be used for treating anemopyretic cold, epidemic febrile disease from the beginning of, headache, conjunctival congestion, sore throat, aphtha, rubella, measles, breast the side of body rise vexed.
Above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit, it is preferred that said composition is
It is prepared from by the raw material of following weight: Cortex Phellodendri 12-15 part, Fructus Quisqualis fruit 22-25 part, Cortex Moutan 12-15 part, anti-
Wind 8-10 part, Camphora 0.2-0.4 part, Herba Menthae 7-9 part；It is further preferred that said composition is former by following weight
Material is prepared from: Cortex Phellodendri 15 parts, Fructus Quisqualis fruit 25 parts, Cortex Moutan 12 parts, Radix Saposhnikoviae 9 parts, Camphora 0.3 part, Herba Menthae 8 parts.Pass through
Above-mentioned preferably the synergistic function that can make compositions is maximum, and acaricide worm effect reaches optimal, side effect minimum.
Above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit, except above-mentioned necessary raw material
Outward, auxiliary material, such as, wetting agent, surfactant, ultraviolet ray-resistant material, alcohols, water can also be added according to actual needs
Deng.
Above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit, can arbitrary proportion and conventional base
Cosmetics made by material, and State of cosmetics can be the one in solution, suspension, emulsion, paste, quintessence oil, spray.
Above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit, said composition is by multiple gentleness
Natural material make, with Fructus Quisqualis fruit as monarch drug, Cortex Phellodendri, Cortex Moutan be ministerial drug, Radix Saposhnikoviae and Herba Menthae be adjuvant drug, Camphora is for making
Medicine, has synergistic function between each compatibility medical material, if having the rapid osmotic acarid that enters skin thus rapid ejection is grown up, rear
Worm, kills larva, pronymph, repairs injured skin, pore refining, reduces the effects such as acarid parasitic probability again, thus reaches
Quickly acaricide worm and the effect of lasting acaricide worm, acaricide worm is effective, and speed is fast, and drug effect is gentle, has no side effect, and is suitable for all kinds of
Skin quality.
Further, the invention provides a kind of Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit
Preparation method, its concrete preparation process is as follows:
1, pulverize after Cortex Phellodendri, Fructus Quisqualis fruit, Cortex Moutan, Radix Saposhnikoviae, Herba Menthae being separately dried, extract and concentrate, obtain Cortex Phellodendri and carry
Take liquid, Fructus Quisqualis fruit extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae extracting solution；
2, the cortex phellodendri extract of step 1 gained, Fructus Quisqualis fruit extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae are extracted
Liquid carries out maturation process respectively, carries out filtering, purifying to obtain each raw material essence after cooling, by each raw material essence mix homogeneously,
Add Camphora, after dissolving, again carry out filtering, purifying, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtain containing Fructus Quisqualis fruit in acaricide worm cosmetics
Drug composition.
The preparation method of above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit, wherein step
To Cortex Phellodendri in 1, Fructus Quisqualis fruit, Cortex Moutan, Radix Saposhnikoviae, the extraction of Herba Menthae, method for concentration are conventional plant extract, method for concentration,
Effective medical active composition in plant can be separated, and increase activity component concentration, improve acaricide worm effect.
The preparation method of above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit, wherein step
In 2, cortex phellodendri extract, Fructus Quisqualis fruit extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae extracting solution are carried out ripening respectively
Process, i.e. carry out plant extraction liquid heating pressurized treatments, destroy the easy allergin in extracting solution, reduce side effect, improve
Adaptability to different skin quality, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, it is right to improve
The seepage velocity of skin.
Wherein, in described curing process, the cooking conditions to each raw material is different, effectively can remove in maximum guarantee
Under the reactive conditions of miticidal activities material, destroy the easy allergin in extracting solution, reduce side effect, and molecular weight is bigger
Active ingredient breaks down becomes the active component of molecular weight, improves the seepage velocity to skin, the tool of its temperature, pressure and time
Body selects as follows:
| Material name | Curing temperature (DEG C) | Ripening pressure (MPa) | Time (h) |
| Cortex Phellodendri | 75-80 | 0.1-0.2 | 1-2 |
| Fructus Quisqualis fruit | 75-80 | 0.1-0.2 | 1-2 |
| Cortex Moutan | 70-75 | 0.1-0.2 | 1-2 |
| Radix Saposhnikoviae | 65-70 | 0.1-0.2 | 2-3 |
| Herba Menthae | 55-60 | 0.1-0.2 | 0.5-1 |
The preparation method of above-mentioned a kind of Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit, by former to difference
Material extracting solution ripening at different conditions, inactivates the easy allergin in raw material extracting solution or decomposes, and retaining and can work in coordination with
Effective medicinal active ingredient of potentiation, and active ingredient breaks down bigger for molecular weight is become the active component of molecular weight, from
And not only reduce the allergy probability of Chinese medicine composition, and improve adaptability, moreover it is possible to improve skin-permeation rate, acaricide worm is imitated
Fruit is more preferable, faster.
Compared with prior art, beneficial effects of the present invention:
1, the present composition passes through the rational compatibility of each raw material, makes different effective active compositions produce synergistic function,
Exciting the property of medicine of effective active matter greatly, acaricide worm is effective, faster.
2, the present composition selects multiple gentle raw material, and formulated by optimal compatibility, drug effect is gentle, has no side effect.
3, Large molecule active substance decomposition is become small-molecule active substance by curing process by the present composition, to skin
Permeability more preferable, improve acaricide worm speed.
4, the easy allergin in raw material extracting solution is processed by the present composition by curing process, reduces easily
Anaphylaxis and side reaction, improve the adaptability of compositions.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But this should not understood
Scope for the above-mentioned theme of the present invention is only limitted to below example, and all technology realized based on present invention belong to this
The scope of invention.
Embodiment 1
1, by Cortex Phellodendri 15 parts, Fructus Quisqualis fruit 25 parts, Cortex Moutan 12 parts, Radix Saposhnikoviae 9 parts, Herba Menthae 8 parts is pulverized after being separately dried, uses ethanol
Solution extracts and concentrates, and obtains cortex phellodendri extract, Fructus Quisqualis really extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae and carries
Take liquid；
2, by the cortex phellodendri extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cold
But Cortex Phellodendri essence is obtained；By the Fructus Quisqualis fruit extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure
Filter, purify, cool down to obtain Fructus Quisqualis fruit essence；By the Cortex Moutan extracting solution of step 1 gained at 73 DEG C, enter under 0.1Mpa pressure
Carry out after row ripening 2h filtering, purifying, cool down to obtain Cortex Moutan essence；By the Radix Saposhnikoviae extracting solution of step 1 gained at 70 DEG C,
Carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Radix Saposhnikoviae essence；The Herba Menthae of step 1 gained is extracted
Liquid, at 58 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Herba Menthae essence under 0.2Mpa pressure；By the Huang of gained
Cypress essence, Fructus Quisqualis fruit essence, Cortex Moutan essence, Radix Saposhnikoviae essence, Herba Menthae essence mix homogeneously, add 0.3
Part Camphora, after dissolving, again purifies, obtains mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtain containing Fructus Quisqualis fruit in acaricide worm cosmetics
Drug composition；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
It is effective that this cosmetic emulsion has acaricide worm, and speed is fast, has no side effect, the advantage of suitable various skin skin quality.
Embodiment 2
1, by Cortex Phellodendri 18 parts, Fructus Quisqualis fruit 30 parts, Cortex Moutan 10 parts, Radix Saposhnikoviae 6 parts, Herba Menthae 9 parts is pulverized after being separately dried, uses ethanol
Solution extracts and concentrates, and obtains cortex phellodendri extract, Fructus Quisqualis really extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae and carries
Take liquid；
2, by the cortex phellodendri extract of step 1 gained at 75 DEG C, carry out after carrying out ripening 2h under 0.1Mpa pressure filtering, purifying, cold
But Cortex Phellodendri essence is obtained；By the Fructus Quisqualis fruit extracting solution of step 1 gained at 70 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure
Filter, purify, cool down to obtain Fructus Quisqualis fruit essence；By the Cortex Moutan extracting solution of step 1 gained at 75 DEG C, enter under 0.1Mpa pressure
Carry out after row ripening 2h filtering, purifying, cool down to obtain Cortex Moutan essence；By the Radix Saposhnikoviae extracting solution of step 1 gained at 65 DEG C,
Carry out after carrying out ripening 3h under 0.1Mpa pressure filtering, purifying, cool down to obtain Radix Saposhnikoviae essence；The Herba Menthae of step 1 gained is extracted
Liquid, at 60 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Herba Menthae essence under 0.2Mpa pressure；By the Huang of gained
Cypress essence, Fructus Quisqualis fruit essence, Cortex Moutan essence, Radix Saposhnikoviae essence, Herba Menthae essence mix homogeneously, add 0.5
Part Camphora, after dissolving, again purifies, obtains mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtain containing Fructus Quisqualis fruit in acaricide worm cosmetics
Drug composition；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
It is effective that this cosmetic emulsion has acaricide worm, has no side effect, the advantage of suitable various skin skin quality.
Embodiment 3
1, by Cortex Phellodendri 10 parts, Fructus Quisqualis fruit 20 parts, Cortex Moutan 15 parts, Radix Saposhnikoviae 10 parts, Herba Menthae 6 parts is pulverized after being separately dried, uses second
Alcoholic solution extracts and concentrates, and obtains cortex phellodendri extract, Fructus Quisqualis fruit extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae
Extracting solution；
2, by the cortex phellodendri extract of step 1 gained at 70 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cold
But Cortex Phellodendri essence is obtained；By the Fructus Quisqualis fruit extracting solution of step 1 gained at 75 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure
Filter, purify, cool down to obtain Fructus Quisqualis fruit essence；By the Cortex Moutan extracting solution of step 1 gained at 70 DEG C, enter under 0.1Mpa pressure
Carry out after row ripening 2h filtering, purifying, cool down to obtain Cortex Moutan essence；By the Radix Saposhnikoviae extracting solution of step 1 gained at 65 DEG C,
Carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Radix Saposhnikoviae essence；The Herba Menthae of step 1 gained is extracted
Liquid, at 55 DEG C, carries out after carrying out ripening 1h filtering, purifying, cool down to obtain Herba Menthae essence under 0.1Mpa pressure；By the Cortex Phellodendri of gained
Essence, Fructus Quisqualis fruit essence, Cortex Moutan essence, Radix Saposhnikoviae essence, Herba Menthae essence mix homogeneously, add 0.2 part
Camphora, after dissolving, purifies again, obtains mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtain containing Fructus Quisqualis fruit in acaricide worm cosmetics
Drug composition；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
It is effective that this cosmetic emulsion has acaricide worm, has no side effect, the advantage of suitable various skin skin quality.
Comparative example 1
1, by Cortex Phellodendri 15 parts, Cortex Moutan 12 parts, Radix Saposhnikoviae 9 parts, Herba Menthae 8 parts is pulverized after being separately dried, extracts with ethanol solution
And concentrate, obtain cortex phellodendri extract, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae extracting solution；
2, by the cortex phellodendri extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cold
But Cortex Phellodendri essence is obtained；By the Cortex Moutan extracting solution of step 1 gained at 73 DEG C, carried out after carrying out ripening 2h under 0.1Mpa pressure
Filter, purification, cool down to obtain Cortex Moutan essence；By the Radix Saposhnikoviae extracting solution of step 1 gained at 70 DEG C, under 0.2Mpa pressure, carry out ripening
Carry out after 2h filtering, purifying, cool down to obtain Radix Saposhnikoviae essence；By the Herba Menthae extracting solution of step 1 gained at 58 DEG C, under 0.2Mpa pressure
Carry out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Herba Menthae essence；By the Cortex Phellodendri essence of gained, Fructus Quisqualis fruit elite
Liquid, Cortex Moutan essence, Radix Saposhnikoviae essence, Herba Menthae essence mix homogeneously, add 0.3 part of Camphora, after dissolving, again carries out
Purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, the Chinese medicine composition for acaricide worm cosmetics obtained；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
Comparative example 2
1, by Fructus Quisqualis fruit 25 parts, Cortex Moutan 12 parts, Radix Saposhnikoviae 9 parts, Herba Menthae 8 parts is pulverized after being separately dried, carries out with ethanol solution
Extract and concentrate, obtain Fructus Quisqualis fruit extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae extracting solution；
2, by the Fructus Quisqualis fruit extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, carrying
Pure, cool down to obtain Fructus Quisqualis fruit essence；By the Cortex Moutan extracting solution of step 1 gained at 73 DEG C, under 0.1Mpa pressure, carry out ripening
Carry out after 2h filtering, purifying, cool down to obtain Cortex Moutan essence；By the Radix Saposhnikoviae extracting solution of step 1 gained at 70 DEG C, 0.2Mpa pressure
Under carry out ripening 2h after carry out filtering, purifying, cool down to obtain Radix Saposhnikoviae essence；By the Herba Menthae extracting solution of step 1 gained at 58 DEG C,
Carry out after carrying out ripening 0.5h under 0.2Mpa pressure filtering, purifying, cool down to obtain Herba Menthae essence；By the Cortex Phellodendri essence of gained,
Fructus Quisqualis fruit essence, Cortex Moutan essence, Radix Saposhnikoviae essence, Herba Menthae essence mix homogeneously, add 0.3 part of Camphora, molten
Xie Hou, purifies again, obtains mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtain containing Fructus Quisqualis fruit in acaricide worm cosmetics
Drug composition；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
Comparative example 3
1, by Cortex Phellodendri 15 parts, Fructus Quisqualis fruit 25 parts, Cortex Moutan 12 parts, Radix Saposhnikoviae 9 parts is pulverized after being separately dried, carries out with ethanol solution
Extract and concentrate, obtain cortex phellodendri extract, Fructus Quisqualis fruit extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution；
2, by the cortex phellodendri extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cold
But Cortex Phellodendri essence is obtained；By the Fructus Quisqualis fruit extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure
Filter, purify, cool down to obtain Fructus Quisqualis fruit essence；By the Cortex Moutan extracting solution of step 1 gained at 73 DEG C, enter under 0.1Mpa pressure
Carry out after row ripening 2h filtering, purifying, cool down to obtain Cortex Moutan essence；By the Radix Saposhnikoviae extracting solution of step 1 gained at 70 DEG C,
Carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Radix Saposhnikoviae essence；By the Cortex Phellodendri essence of gained, make
Gentleman fruit essence, Cortex Moutan essence, Radix Saposhnikoviae essence mix homogeneously, add 0.3 part of Camphora, after dissolving, again carry out
Purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtain containing Fructus Quisqualis fruit in acaricide worm cosmetics
Drug composition；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
Comparative example 4
1, by Cortex Phellodendri 20 parts, Fructus Quisqualis fruit 15 parts, Cortex Moutan 12 parts, Radix Saposhnikoviae 9 parts, Herba Menthae 8 parts is pulverized after being separately dried, uses ethanol
Solution extracts and concentrates, and obtains cortex phellodendri extract, Fructus Quisqualis really extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae and carries
Take liquid；
2, by the cortex phellodendri extract of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure filtering, purifying, cold
But Cortex Phellodendri essence is obtained；By the Fructus Quisqualis fruit extracting solution of step 1 gained at 78 DEG C, carry out after carrying out ripening 1h under 0.2Mpa pressure
Filter, purify, cool down to obtain Fructus Quisqualis fruit essence；By the Cortex Moutan extracting solution of step 1 gained at 73 DEG C, enter under 0.1Mpa pressure
Carry out after row ripening 2h filtering, purifying, cool down to obtain Cortex Moutan essence；By the Radix Saposhnikoviae extracting solution of step 1 gained at 70 DEG C,
Carry out after carrying out ripening 2h under 0.2Mpa pressure filtering, purifying, cool down to obtain Radix Saposhnikoviae essence；The Herba Menthae of step 1 gained is extracted
Liquid, at 58 DEG C, carries out after carrying out ripening 0.5h filtering, purifying, cool down to obtain Herba Menthae essence under 0.2Mpa pressure；By the Huang of gained
Cypress essence, Fructus Quisqualis fruit essence, Cortex Moutan essence, Radix Saposhnikoviae essence, Herba Menthae essence mix homogeneously, add 0.3
Part Camphora, after dissolving, again purifies, obtains mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtain containing Fructus Quisqualis fruit in acaricide worm cosmetics
Drug composition；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
Comparative example 5
1, by Cortex Phellodendri 15 parts, Fructus Quisqualis fruit 25 parts, Cortex Moutan 12 parts, Radix Saposhnikoviae 9 parts, Herba Menthae 8 parts is pulverized after being separately dried, uses ethanol
Solution extracts and concentrates, and obtains cortex phellodendri extract, Fructus Quisqualis really extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae and carries
Take liquid；
2, the cortex phellodendri extract of step 1 gained, Fructus Quisqualis fruit extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Camphora are extracted
Liquid, Herba Menthae extracting solution mix homogeneously, add 0.3 part of Camphora, after dissolving, again purify, obtain mixing essence；
3, mixing essence step 2 obtained carries out homogenizing, obtain containing Fructus Quisqualis fruit in acaricide worm cosmetics
Drug composition；
4, take respectively acaricide worm Chinese medicine composition that percentage by weight is 10%, the glycerol of 15%, the sorbitol olein of 10%,
The purified water of 65% makes acaricide worm cosmetic emulsion.
Acaricide worm cosmetics above-described embodiment 1-3 and comparative example 1-5 obtained are tried out, and randomly choose 50 by demodicid mite
The mild skin disease volunteer that worm causes, is divided into 10 groups, and wherein 1-8 uses the cosmetic that embodiment and comparative example prepare respectively
Product, select the acaricide worm cosmetics that commercial type is best for the 9th group, and the 10th group, for not use acaricide worm cosmetics, uses respectively
5, after 10,15 days and suspend and use after 10 days, acaricide worm effect is detected and evaluates, records as follows:
| Group Not | Use front acarid par (individual/cm2) | Acarid average after using 5 days Amount (individual/cm2) | Acarid average after using 10 days Amount (individual/cm2) | Use 15 days acarid pars (individual/cm2) | Suspend and use 10 days acarid averages Amount (individual/cm2) |
| 1 | 10.1 | 4.0 | 0.6 | 0.3 | 0.5 |
| 2 | 9.5 | 3.2 | 0.4 | 0.2 | 0.6 |
| 3 | 10.5 | 3.5 | 0.5 | 0.2 | 0.6 |
| 4 | 9.9 | 8.6 | 6.3 | 6.1 | 7.3 |
| 5 | 10.6 | 6.3 | 5.2 | 4.6 | 6.8 |
| 6 | 11.1 | 6.8 | 5.8 | 4.8 | 6.5 |
| 7 | 9.6 | 7.6 | 7.2 | 6.5 | 8.3 |
| 8 | 10.2 | 4.6 | 2.7 | 1.4 | 1.5 |
| 9 | 9.8 | 6.8 | 4.2 | 3.5 | 5.1 |
| 10 | 10.3 | 10.4 | 10.5 | 10.5 | 10.6 |
From above proof test data, 1-3 group (embodiment 1-3) have employed present composition raw material composition and joins
The acaricide worm Chinese medicine composition that side prepares, has synergistic function, and acaricide worm effect is notable, and speed is fast, and persistently has
Effect；4th group (comparative example 1) does not adds monarch drug Fructus Quisqualis fruit, and compositions compatibility changes completely, and drug effect changes, and acaricide worm effect is very
Difference；5th group (comparative example 2) does not adds ministerial drug Cortex Phellodendri, and compositions compatibility changes, and loses synergistic function, acaricide between medical material
Worm effect is deteriorated；6th group (comparative example 3) does not adds adjuvant drug Herba Menthae, and compositions compatibility changes, and loses Synergistic and make between medical material
With, acaricide worm effect is deteriorated；7th group (comparative example 4) does not use the raw material number of the present composition, and compatibility changes, yellow
Bai Chengwei monarch drug, Fructus Quisqualis fruit becomes ministerial drug, and the overall property of medicine of compositions prepared changes, and also loses collaborative increasing between medical material
Effect effect, acaricide worm effect is deteriorated；The method that 8th group (comparative example 5) does not use the present invention to prepare compositions, has relatively equally
Good acaricide worm effect, but the onset of drug effect slows, and the acaricide worm time is elongated；9th group is that existing acaricide worm cosmetics make
Using rear situation, its acaricide worm effect is general, and speed is general, after cutting time-out use, and acarid secondary parasite the most again.
Claims (9)
1. the Chinese medicine composition for acaricide worm cosmetics containing Fructus Quisqualis fruit, it is characterised in that described compositions is
It is prepared from by the raw material of following weight: Cortex Phellodendri 10-18 part, Fructus Quisqualis fruit 20-30 part, Cortex Moutan 10-15 part, anti-
Wind 6-10 part, Camphora 0.2-0.5 part, Herba Menthae 6-9 part.
Chinese medicine composition the most according to claim 1, it is characterised in that described compositions is former by following weight
Material is prepared from: Cortex Phellodendri 12-15 part, Fructus Quisqualis fruit 22-25 part, Cortex Moutan 12-15 part, Radix Saposhnikoviae 8-10 part, Camphora 0.2-0.4
Part, Herba Menthae 7-9 part.
Chinese medicine composition the most according to claim 2, it is characterised in that described compositions is former by following weight
Material is prepared from: Cortex Phellodendri 15 parts, Fructus Quisqualis fruit 25 parts, Cortex Moutan 12 parts, Radix Saposhnikoviae 9 parts, Camphora 0.3 part, Herba Menthae 8 parts.
4. according to Chinese medicine composition described in any one of claim 1-3, it is characterised in that the preparation side of described Chinese medicine composition
Method, its concrete preparation process is as follows:
(1), Cortex Phellodendri, Fructus Quisqualis fruit, Cortex Moutan, Radix Saposhnikoviae, Herba Menthae are separately dried after pulverize, extract and concentrate, obtain Cortex Phellodendri
Extracting solution, Fructus Quisqualis fruit extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae extracting solution；
(2), the cortex phellodendri extract of step 1 gained, Fructus Quisqualis fruit extracting solution, Cortex Moutan extracting solution, Radix Saposhnikoviae extracting solution, Herba Menthae are carried
Take liquid and carry out maturation process respectively, carry out after cooling filtering, purifying to obtain each raw material essence, by the mixing of each raw material essence all
Even, add Camphora, after dissolving, again carry out filtering, purifying, obtain mixing essence；
(3) the mixing essence, by step 2 obtained carries out homogenizing, obtain containing Fructus Quisqualis fruit for acaricide worm cosmetics
Chinese medicine composition.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Cortex Phellodendri
The curing temperature of extracting solution is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, make monarch
The curing temperature of son fruit extracting solution is 75-80 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Paeonia suffruticosa
The curing temperature of peel extract is 70-75 DEG C, pressure is 0.1-0.2Mpa, the time is 1-2h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Radix Saposhnikoviae
The curing temperature of extracting solution is 65-70 DEG C, pressure is 0.1-0.2Mpa, the time is 2-3h.
Chinese medicine composition the most according to claim 4, it is characterised in that in the preparation method step 2 of described compositions, Herba Menthae
The curing temperature of extracting solution is 55-60 DEG C, pressure is 0.1-0.2Mpa, the time is 0.5-1h.
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