CN1413627A - Medicine for treating dematosis - Google Patents
Medicine for treating dematosis Download PDFInfo
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- CN1413627A CN1413627A CN 02118272 CN02118272A CN1413627A CN 1413627 A CN1413627 A CN 1413627A CN 02118272 CN02118272 CN 02118272 CN 02118272 A CN02118272 A CN 02118272A CN 1413627 A CN1413627 A CN 1413627A
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Abstract
A Chinese medicine in the form of powder for treating dermatopathy is prepared from 12 Chinese-medicinal materials including cnidium fruit, flavescent sophora root, dittany bark, China root, etc. through drying, pulverizing and proportional mixing, and separately packing realgar and alums. It has high curative effect.
Description
One, technical field
The present invention relates to the dermopathic medicine of a kind of treatment, particularly relating to a kind of is the dermopathic medicine of treatment that raw material is made with plant, mineral Chinese herbal medicine.
Two, background technology
Dermatosis is commonly encountered diseases, frequently-occurring disease clinically, also is the stubborn disease that is difficult to cure.Though it is more to treat dermopathic medicine now, but most medicines also can only play the effect of relief of symptoms, fundamentally cure difficulty, the Western medicine medicine for external use of synthetic mainly is a hormone medicine, certain side effect is arranged again, " JIEERYIN " arranged in the Chinese medicine, and this medicine is to the dermatosis DeGrain of fungal infection.
Chinese patent 97116484.3 discloses " the dermopathic pharmaceutical composition of a kind of treatment ", and technical scheme is Fructus Kochiae 10-20, Fructus Xanthii 10-20, Fructus Cnidii 10-20, favus skin 15-25, Radix Scrophulariae 5-15, Rhizoma Acori Graminei 5-15, Herba Ecliptae 5-15, money wind 5-15, Herba Hieracii Umbellati 0.5-2, Radix Sophorae Flavescentis 5-15, Folium Eucalypti Robustae 10-20, Borneolum Syntheticum 3-10.Effective in cure to dermatosis such as psoriasis, chronic eczema, skin itching, vitiligo.
Another Chinese patent 00100275.9 discloses " the dermopathic medicine of a kind of treatment ", and it is Radix Bupleuri 10-20, Cortex Phellodendri 10-20, Radix Gentianae 10-20, Radix Saposhnikoviae 10-20, Fructus Kochiae 10-15, Rhizoma Smilacis 10-20, Herba Taraxaci 15-25, Fructus Forsythiae 15-25, Radix Angelicae Sinensis 10-20, Rhizoma Atractylodis Macrocephalae 10-18, Radix Angelicae Dahuricae 5-15, Rhizoma Smilacis Glabrae 10-20, lid intelligence core 10-15, favus skin 10-15, Medulla Tetrapanacis 10-15, Rhizoma Alismatis 10-15, Cornu Bubali 10-20, Flos Carthami 10-15 that its medicine is formed.Cure mainly diseases such as rheumatism poison rash, skin infection scabies carbuncle, gonorrhea, syphilis, condyloma acuminatum, pathological changes dermatoses, lupus erythematosus.
Above-mentioned binomial all can not be brought into play drug effect rapidly, promotes the fast Absorption of medicine, can not quicken the partial blood circulation of skin lesion.
Three, summary of the invention
The object of the present invention is to provide a kind of Chinese medicine that can treat the various skin disease.
Another object of the present invention provides the sick preparation method of Chinese medicine of treatment various skin.
Solution of the present invention is based on motherland's medical science to pathogenetic understanding of various dermatosiss and Therapeutic Principle, achieve with reference to modern pharmacological research, from motherland's medicine treasure-house, filter out the detoxifcation of dampness removing to stop itchin, parasite killing, drying damp and strengthening spleen, expelling pathogenic wind from the body surface, delousing parasite killing, relieving stranguria by diuresis, the natural plants of heat-clearing and toxic substances removing, mineral drug, press the tcm theory prescription, skim the cream off milk, make the original therapeutic effect of its performance, reach the purpose of curing the various skin disease.
Medicine of the present invention is made by following ingredients: (consumption is a weight portion)
Fructus Cnidii 20-10, Radix Sophorae Flavescentis 20-10, favus skin 20-10,
Rhizoma Smilacis Glabrae 20-10, native skin 20-10, Radix Stemonae 20-10,
Fructus Quisqualis 20-10, Radix Saposhnikoviae 20-10, Rhizoma Atractylodis 20-10,
Cortex Phellodendri 20-10, Realgar 8-4, Alumen 8-4
Formula optimization weight (part) ratio range of preparation medicine of the present invention is: Fructus Cnidii 15-8, Radix Sophorae Flavescentis 15-8, favus skin 15-8, Rhizoma Smilacis Glabrae 15-8, native skin 15-8, Radix Stemonae 15-8, Fructus Quisqualis 15-8, Radix Saposhnikoviae 15-8, Rhizoma Atractylodis 15-8, Cortex Phellodendri 15-8, Realgar 6-3, Alumen 6-3.
The best in quality of medicine of the present invention (part) proportioning is:
Fructus Cnidii 10, Radix Sophorae Flavescentis 10, favus skin 10, Rhizoma Smilacis Glabrae 10, the Fructus Kochiae 10, the Radix Stemonae 10, Fructus Quisqualis 10, Radix Saposhnikoviae 10, Rhizoma Atractylodis 10, Cortex Phellodendri 10, Realgar 4, Alumen 4.
The pharmaceutically dosage form of medicine of the present invention can be a said dosage form on any pharmaceutics, usually medicine of the present invention is made into powder or piece agent.
The using method of pharmaceutical composition of the present invention is: with (1)-(10) ten flavor Chinese medicines, use clear water 1000-2000ml, soak 10-20min, 50-60min is fried in shallow oil with slow fire is slow in the back, medicine juice is blended in the basin, respectively with Realgar end 2g, Alumen end 2g, be sprinkled in the medicine juice, take advantage of heat to smoke earlier and afterwards wash affected part.(adult, or people among a small circle bathe the time of washing and can suitably grow, and child and large-area, the bath time of washing can lack, with anti-poisoning).Can add clear water 1000-2000ml again next day with frying in shallow oil the back medicinal residues, continues to fry in shallow oil equally to wash.Each agent Chinese medicine can be fried in shallow oil to smoke and wash secondary, once a day.Two doses of general logotypes, smoking and washing four times is a course of treatment.(and child especially smoked with interior child and washes at interval and should prolong in three years old, general first dose of Chinese medicine, and secondary smokes to be washed, midfeather one day---and smoked in promptly three days and to wash secondary; At interval 3-5 days again, smoke and wash second dose, at interval as before, smoked in three days and to wash secondary).
Each material medicine uses the raw medicinal material that meets the medical material standard in the aforementioned pharmaceutical compositions, and the pharmacology of its each crude drug is:
(1) Fructus Cnidii: hot, bitter, warm, slightly poisonous, return kidney channel, removing dampness and killing parasites, cold expelling dispel the wind, warming the kidney to invigorate YANG;
(2) Radix Sophorae Flavescentis: bitter, cold, GUIXIN, liver, stomach, large intestine, urinary bladder channel
Wind dispelling insecticide, heat clearing and damp drying, diuresis
Also have effects such as antiallergic, diuresis, blood pressure lowering, to dysentery bacterium, escherichia coli, and infusorian etc. inhibitory action is all arranged.
(3) favus skin: bitter, tremble with fear, return spleen, stomach warp
Heat clearing and damp drying, dispelling wind for relieving itching
Multiple pathomycete there is inhibitory action.
(4) Rhizoma Smilacis Glabrae: sweet, light, put down, return liver, stomach warp
Heat-clearing and toxic substances removing, sharp joint
Treponema pallidum and leptospira are all had inhibition and killing action, are the main specially medicines of controlling syphilis.
(5) Fructus Kochiae: sweet, bitter, tremble with fear, return kidney, urinary bladder channel
Relieving stranguria by diuresis, removing damp to relieve itching, make eye bright
Fungus there is inhibitory action, also has anti rheumatism action.
(6) Radix Stemonae: sweet, bitter, put down, return lung meridian, slightly poisonous
Nourishing the lung to arrest cough, delousing parasite killing
Antihistamine effect is arranged, staphylococcus aureus, Bacillus tuberculosis, streptococcus pneumoniae, escherichia coli, dysentery bacterium, influenza virus and dermatophytes etc. are all had inhibitory action, its water and pure immersion all have killing action to mosquito, fly larva and head louse and Cimex bedbug.
(7) Fructus Quisqualis: sweet, wet, slightly poisonous, return spleen, stomach warp
Parasite killing, spleen invigorating removing food stagnancy
To ascarid, Lumbricus, dawn worm etc. all have and suppress and killing action, the various skin fungus is had inhibitory action.
(8) Radix Saposhnikoviae: hot, sweet, warm, return bladder, lung, spleen channel
Expelling pathogenic wind from the body surface, pain relieving, spasmolytic, antipruritic
Experimental arthritis there is inhibitory action, some antiepileptic action is arranged, bacillus pyocyaneus and staphylococcus aureus are all had certain antibacterial action.
(9) Rhizoma Atractylodis: hot, bitter, temperature, return spleen, stomach warp
Drying damp and strengthening spleen, diaphoresis is dispeled the wind, is made eye bright
Calmness, anticonvulsant action are arranged, hepatocyte is had protective effect, external esophageal cancer cell is had inhibitory action.
(10) Cortex Phellodendri; Bitter, tremble with fear, return kidney, bladder, large intestine channel
Heat clearing and damp drying, eliminating fire and detoxication, hemostasis
To staphylococcus aureus, dysentery bacterium, escherichia coli, tubercule bacillus, multiple pathogenic dermatophytes, vagina three infusorian, leptospira etc. all have inhibitory action.
(11) Realgar: hot, bitter, warm, poisonous, GUIXIN, liver, stomach warp
Composition: mainly contain realgar (AS
2S
2) and a small amount of other slaine
Parasite killing detoxifies, the arresting convulsion preventing the attack (or recurrence) of malaria eliminates the phlegm
Multiple pathogenic dermatophytes there is inhibitory action in various degree, schistosomicide and plasmodium effect are arranged.Annotate easily from skin, mucosa absorption.Avoid fire and forge and fry in shallow oil stir-fry.
(12) Alumen: composition: aluminium potassium sulfate
Sour, puckery, tremble with fear, return lung, spleen, stomach, large intestine channel
Detoxifcation parasite killing, dampness removing to stop itchin, hemostasis, antidiarrheal, heat clearing away expectorant
Antiinflammatory, convergence, antisepsis are arranged, and can coagulated protein, sclerosis skin, hemostasis; Various bacteria there is inhibitory action.
Toxicity test:
Select 10 one group of white mice for use, amount to 5 groups:
First group, with the former dose of this powder prescription, take juice and be blended in the basin, when being cooled to 30 ℃-40 ℃ approximately, 10 white mice are dropped into, soak about 30min, take out white mice, observe 24h, the white mice vigor does not have any variation.
Second group, amplify 2 times with each dose of this powder prescription, carry out the same test, come to the same thing.
The 3rd group: amplify 3 times with each dose of this powder prescription, test equally, can find have 1 white mice fidgety a bit, uneasiness.
The 4th group: amplify 4 times with each dose of this powder prescription, test equally, can find half (4-5 only) white mice, some dysphoria.
The 5th group: amplify 5 times with each dose of this powder prescription, test equally, can find, (6-8 only) more than half white mice dysphoria is arranged, but do not have drowsiness shape, do not have the phenomena of mortality.
Model case:
1, Yu Rangping, the man, 26 years old, tame people from shallow lake deceived in river mouth, Qianshan County town, and the carpenter is unmarried, suffers from head (deceiving) tinea about 5 years, fails to respond to any medical treatment through many prescription drugss, so come institute to go to a doctor October 16 calendar year 2001.The heart, lung, liver,spleen,kidney (), rarely seen skin ulcer of tinea all over the face, the oil spilling fat that has, the knot scab that has, have because of the hands hemorrhage of scratching, with a large amount of alopecias, abnormal smells from the patient raw meat, acid, smelly; Especially with the forehead hairline place for very.The private prosecution scalp is very itched, and after fatigue, during perspiration, ambient temperature increases the weight of when raising, and has a large amount of dandruff to come off, and a large amount of alopecias is arranged when hands scratches.Through using two doses of pharmaceutical compositions of the present invention, smoke and wash 4 times, recovery from illness, not recurrence so far.
2, section builds loyalty, man, 22 years old, river mouth, Qianshan County town anxiety household, peasant.Patient's both hands ten refer to tinea unguium, about 7 years.Private prosecution before 7 years, because of suffering from " tinea pedis-smelly feet (mycotic toenail, toe ditch inflammation) ", hands scratching foot pruritus commonly used, tinea unguium is caused in the back, the foot disease is because of fully recovering with " JIAOXIAN YICIJING ", and tinea unguium does not heal so far, so come institute's prescription on individual diagnosis.PE: the heart, lung (), rarely seen both hands ten fingernails rewind, thick, dry, matt always, are grey black, embrittlement, easy fracture, no gargalesthesia.Advise elder generation with little paper cutter, nail polisher is extremely belittled, two doses of the same usefulness (frying in shallow oil lotion) add and take 21 JIWEITA (people's livelihood).Be almost recovered, imitate good.
3, Zhang Aidi, the woman, 68 years old, the strong bridge in river mouth, Qianshan County took the household.The private prosecution biped itches, dry, peel, chap, the pain of walking about ten years.PE: the heart, lung () biped are " bow bridge " shape deformity (due to binding the feet of women), the decortication of vola large tracts of land, and drying is chapped, and dehiscence furrow has and mark, and the toes ditch is pale, stench.Clinical diagnosis is sufficient fungal infection, nervus plantaris dermatitis, baldness.The same use smokes for four doses and washes, recovery from illness.
4, Liu Xiaoqing, man, 18M
+, river mouth, Qianshan County town good fortune favour people, its mother tells in generation, and itch all over sends out malicious the rash pact half a year, and fail to respond to any medical treatment in many places.PE: the vital sign balance, the heart, lung (), liver, spleen () see that whole body has a large amount of, old grey black scar, and the purpureal macule point of a large amount of New Developments is also arranged, the infection suppurates that has is very itched.Illustrate by this (frying in shallow oil lotion), use 2 doses, add the intramuscular injection penicillin, polyinosini.Recovery from illness, not recurrence so far.
5, Lv Meisheng, man, 32 years old, the new beach village people in Qianshan County.The electrician has 6 years chronic prostatitis medical histories, now cures.Very itch in 2001.9.10 sense pudendum, wet greasy, twinge is difficult to adhere to work.Come institute to go to a doctor in 2001.9.22.PE: cardiopulmonary (), see that urethral orifice has a small amount of pus to overflow, urethral orifice is rubescent to be with redly, and dampness of scrotum has lichenification trend, the femoribus internus flushing.At microscopically, can find gonococcus.Clinical diagnosis: gonococcus urethritis, eczema scrotum.Give anti-gonococcus antiinflammatory, add usefulness (frying in shallow oil lotion) and smoke and wash 4 times, smoke at every turn wash after, add and pounce on six refreshing talcum powder, recovery from illness.
6, Hu Wenhua, the woman, 5 years old, people sieve was close in the Qianshan County.Suffer from the multiple impetigo of child's whole body, some is formed a scab, have in New Development, be full of pus in the herpes that has.T39.5 ℃, P28 time, xerostomia, the uneasiness of crying and screaming.Use two doses with this (frying in shallow oil lotion) by its explanation, add the intramuscular injection penicillin, polyinosini, recovery from illness.
7, Jiang Ailan, woman, 36 years old, river mouth, Qianshan County people from town.Private prosecution pudendal pruritus, twinge, dysurea, frequent micturition is anxious, lower abdomen dull pain, soreness of waist pain.PE:T37.8 ℃ (mouth), BP109/70mmHg, the pudendum flushing, urethral orifice is rubescent swollen, and the vaginal orifice adularescent is bean curd slag specimen secretions.Vaginal speculum expands vagina to be opened, and intravaginal has a large amount of whites, the bean curd slag specimen, and thing in the form of sheets, orifice of uterus three degree are rotten to the corn, and rotten odor is arranged.Mirror is looked into, and is fungal infection.Orifice of uterus is given heat and is burnt, and smoke with this (frying in shallow oil lotion) row pudendum and wash, and the vagina lavation, recovery from illness.
8, Hu Jianmin, man, 28 years old, people from Zhejiang, trade.Large hospital is diagnosed as syphilis in Zhejiang, 1 phase.PE: cardiopulmonary (), penis coronary sulcus has the stone wart, and quality is hard, and it is not obvious to keenly feel.Use this (frying in shallow oil lotion) 4 doses, recovery from illness was married after 1 year, gave birth to boy, child's health.
Begin in March, 2002 from October nineteen ninety, with Drug therapy of the present invention dissimilar dermatosiss, comprise multiple ringworm, intractable scabies disease, skin infection, intractable rot skin ulcer, the malicious rash of unknown cause, impetigo, bubble rash, neurodermatitis, silver bits disease, decortication disease, various wet disease, and some skin carcinoma, especially man, women various pudendal pruritus diseases, gonorrhea, syphilis all have good curative effect reliably.Accumulative total has been accepted 466 routine patients for medical treatment, has carried out treatment and has observed, and has proved that this powder agent medicine has original curative effect to the various skin disease.
The clinical efficacy table
The sick kind | Case load | Cure | Produce effects | Effectively | Invalid | Effective percentage |
Eczema, sexually transmitted disease (STD) ringworm, scabies disease skin infection, dermatitis etc. | ?466 | ???412 | ??30 | ??20 | ???4 | ???99.14% |
Clinical drug of the present invention uses the result to show to have following advantage:
1, to select natural plant, mineral drug for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation.Utilize the comprehensive function treatment dermatosis of the Chinese medicine of respectively distinguishing the flavor of, harmless to the human body low toxicity.
2, the present invention is an external used medicine, need not be oral, and need only smoke to wash and get final product.Employing smokes the lotion type, and local patholoic change is utilized to smoke and washed, and helps medicine and brings into play effects such as cleaning, sterilization, sterilization rapidly, helps drug absorption, helps the local blood circulation of skin lesion and accelerates, and promotes rehabilitation.
3, light disease person can use separately, can unite use with other drug than serious symptom person, and therapeutic effect obviously increases, and is easy to use, safe, effective.
4, medicine of the present invention is to the various fungus-caused multiple ringworms of body surface, and malicious rash, obstinate mashed skin ulcer, pustule, herpes, neurodermatitis, the silver of scabies disease, skin infection, unknown cause is considered disease, decortication disease, various wet disease to be worth doing due to the acarid, some skin carcinoma, various poisonous snakes, insect-bite, especially man, the various pudendal pruritus diseases of female genital, gonorrhea, syphilis all have better curative effect reliably.
Four, embodiment
Take by weighing raw material (gram) by following proportioning:
Fructus Cnidii: 10 Radix Sophorae Flavescentiss: 10 favus skins: 10 Rhizoma Smilacis Glabraes: 10
The Fructus Kochiae: 10 Radixs Stemonae: 10 Fructus Quisqualis: 10 Radix Saposhnikoviaes: 10
Rhizoma Atractylodis: 10 Cortex Phellodendris: 10 Realgars: 4 Alumen: 4
Above-mentioned each component is made medicine production method of the present invention is: pulverize separately, be mixed in proportion the back packing by preceding ten flavors, and back two flavors are packing respectively.
Claims (5)
1, the dermopathic medicine of a kind of treatment is characterized in that it is the medicament of being made by the following weight proportion raw material:
Fructus Cnidii: 20-10 Radix Sophorae Flavescentis: 20-10
Favus skin: 20-10 Rhizoma Smilacis Glabrae: 20-10
The Fructus Kochiae: the 20-10 Radix Stemonae: 20-10
Fructus Quisqualis: 20-10 Radix Saposhnikoviae: 20-10
Rhizoma Atractylodis: 20-10 Cortex Phellodendri: 20-10
Realgar: 8-4 Alumen: 8-4
2, the dermopathic medicine of treatment according to claim 1, wherein the weight proportion of each raw material is:
Fructus Cnidii: 15-8 Radix Sophorae Flavescentis: 15-8
Favus skin: 15-8 Rhizoma Smilacis Glabrae: 15-8
The Fructus Kochiae: the 15-8 Radix Stemonae: 15-8
Fructus Quisqualis: 15-8 Radix Saposhnikoviae: 15-8
Rhizoma Atractylodis: 15-8 Cortex Phellodendri: 15-8
Realgar: 6-3 Alumen: 6-3
3, the dermopathic medicine of treatment according to claim 1, wherein the weight proportion of each raw material is:
Fructus Cnidii: 10 Radix Sophorae Flavescentiss: 10
Favus skin: 10 Rhizoma Smilacis Glabraes: 10
The Fructus Kochiae: 10 Radixs Stemonae: 10
Fructus Quisqualis: 10 Radix Saposhnikoviaes: 10
Rhizoma Atractylodis: 10 Cortex Phellodendris: 10
Realgar: 4 Alumen: 4
4,, it is characterized in that said medicament is a said dosage form on any pharmaceutics according to claim 1, the dermopathic medicine of 2 or 3 described treatments.
5, the dermopathic medicine of treatment according to claim 4 is characterized in that said medicament is powder or piece agent.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CNB021182728A CN1190217C (en) | 2002-05-04 | 2002-05-04 | Medicine for treating dematosis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CNB021182728A CN1190217C (en) | 2002-05-04 | 2002-05-04 | Medicine for treating dematosis |
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Publication Number | Publication Date |
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CN1413627A true CN1413627A (en) | 2003-04-30 |
CN1190217C CN1190217C (en) | 2005-02-23 |
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CNB021182728A Expired - Fee Related CN1190217C (en) | 2002-05-04 | 2002-05-04 | Medicine for treating dematosis |
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